Amaç: Fetal dönemde büyüme kısıtlılığı, ileri yaşlarda metabolik hastalıkların gelişimini etkileyebilir. Bu çalışmada, fetal malnütrisyonu olan ve olmayan term yenidoğan bebeklerin ilk iki yaştaki büyümelerinin ve ikinci yaştaki glukoz, insülin ve lipid profillerinin karşılaştırılması amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya Mayıs 2019 ile Ekim 2019 tarihleri arasında hastanemizde doğan, CANSCORE yöntemi kullanılarak fetal malnütrisyon saptanan ve saptanmayan term bebekler alındı. Umblikal kord kanında insülin, glukoz, total kolesterol, LDL kolesterol, HDL kolesterol, VLDL kolesterol, trigliserid değerlerine bakıldı. Bu bebeklerin iki yaşına kadar büyümeleri takip edildi. İkinci yıl sonunda aynı paramtrelere yeniden bakıldı. Bulgular: Fetal malnutrisyon saptanan 40 bebekten 26’sı, fetal malnutrisyon saptanmayan 40 bebekten 22’si iki yıl boyunca takip edildi. Fetal malnütrisyonu olan bebeklerin 6. ayında vücut ağırlığı, boy uzunluğu ve baş çevresinin, fetal malnütrisyonlu olmayan bebeklere göre daha yüksek olduğu ancak 12 ve 24. ayda bu farkın gerilediği görüldü. Yaşamının ikinci yılında bakılan glikoz, insülin, total kolesterol, LDL kolesterol, HDL kolesterol düzeyleri arasında her iki grup arasında anlamlı farklılık yokken, VLDL kolesterol ve trigliserid düzeyleri fetal malnütrisyonu olan grupta anlamlı olarak daha yüksek saptandı. Sonuç: Fetal malnütrisyonlu bebeklerde yaşamının ilk 6 ayındaki hızlı kilo artışı erken çocukluk dönemindeki lipid profilini etkileyebilir.
{"title":"Growth, glucose, insulin and lipid profile in the first two years of term infants with fetal malnutrition","authors":"S. Tanrıverdi","doi":"10.38136/jgon.1061312","DOIUrl":"https://doi.org/10.38136/jgon.1061312","url":null,"abstract":"Amaç: Fetal dönemde büyüme kısıtlılığı, ileri yaşlarda metabolik hastalıkların gelişimini etkileyebilir. Bu çalışmada, fetal malnütrisyonu olan ve olmayan term yenidoğan bebeklerin ilk iki yaştaki büyümelerinin ve ikinci yaştaki glukoz, insülin ve lipid profillerinin karşılaştırılması amaçlanmıştır. \u0000 \u0000Gereç ve Yöntemler: Çalışmaya Mayıs 2019 ile Ekim 2019 tarihleri arasında hastanemizde doğan, CANSCORE yöntemi kullanılarak fetal malnütrisyon saptanan ve saptanmayan term bebekler alındı. Umblikal kord kanında insülin, glukoz, total kolesterol, LDL kolesterol, HDL kolesterol, VLDL kolesterol, trigliserid değerlerine bakıldı. Bu bebeklerin iki yaşına kadar büyümeleri takip edildi. İkinci yıl sonunda aynı paramtrelere yeniden bakıldı. \u0000 \u0000Bulgular: Fetal malnutrisyon saptanan 40 bebekten 26’sı, fetal malnutrisyon saptanmayan 40 bebekten 22’si iki yıl boyunca takip edildi. Fetal malnütrisyonu olan bebeklerin 6. ayında vücut ağırlığı, boy uzunluğu ve baş çevresinin, fetal malnütrisyonlu olmayan bebeklere göre daha yüksek olduğu ancak 12 ve 24. ayda bu farkın gerilediği görüldü. Yaşamının ikinci yılında bakılan glikoz, insülin, total kolesterol, LDL kolesterol, HDL kolesterol düzeyleri arasında her iki grup arasında anlamlı farklılık yokken, VLDL kolesterol ve trigliserid düzeyleri fetal malnütrisyonu olan grupta anlamlı olarak daha yüksek saptandı. \u0000 \u0000Sonuç: Fetal malnütrisyonlu bebeklerde yaşamının ilk 6 ayındaki hızlı kilo artışı erken çocukluk dönemindeki lipid profilini etkileyebilir.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115372839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Serdar, Günsu KİMYON CÖMERT, Özgün Ceylan, İrem Kar, H. Yalçin, Taner Turan
Aim: The aim of this study is evaluating the predictive value of preoperative inflammatory blood parameters for differential of serous cystadenoma, serous borderline ovarian tumor (BOT) and high-grade serous ovarian (HGSOC) carcinoma. Materials and Method: In this single-center study, we retrospectively enrolled 370 patients with ovarian tumors were divided into three groups. The groups were classified as serous cystadenoma, serous BOT and HGSOC. The potential association of preoperative hemoglobin (Hb), red cell distribution width (RDW), Hb/RDW ratio, ratio of neutrophils to lymphocytes (N/L) and ratio of platelets to lymphocytes (P/L) were analyzed. Results: P/L and N/L were significantly lower in benign serous cystadenoma or serous BOT than HGSOC (p
{"title":"Over tümörlerinin ayırıcı tanısında sistemik inflamatuar belirteçlerin rolü","authors":"S. Serdar, Günsu KİMYON CÖMERT, Özgün Ceylan, İrem Kar, H. Yalçin, Taner Turan","doi":"10.38136/jgon.1278471","DOIUrl":"https://doi.org/10.38136/jgon.1278471","url":null,"abstract":"Aim: The aim of this study is evaluating the predictive value of preoperative inflammatory blood parameters for differential of serous cystadenoma, serous borderline ovarian tumor (BOT) and high-grade serous ovarian (HGSOC) carcinoma. \u0000Materials and Method: In this single-center study, we retrospectively enrolled 370 patients with ovarian tumors were divided into three groups. The groups were classified as serous cystadenoma, serous BOT and HGSOC. The potential association of preoperative hemoglobin (Hb), red cell distribution width (RDW), Hb/RDW ratio, ratio of neutrophils to lymphocytes (N/L) and ratio of platelets to lymphocytes (P/L) were analyzed. \u0000Results: P/L and N/L were significantly lower in benign serous cystadenoma or serous BOT than HGSOC (p","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132319203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amaç: Antenatal bakıma ulaşamayan sığınmacı gebelerin maternal ve neonatal sonuçlarının değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Bu çalışmada bir eğitim ve araştıma hastanesi doğum salonuna Ocak 2013-Ocak 2015 tarihleri arasında yatrılan ve gebeliği boyunca takip almayan 202 sığınmacı gebe dahil edildi. Çalışma etik kurul tarafından onaylandı. Suriyeli sığınmacı gebelerin maternal ve neonatal sonuçları değerlendirildi. Bulgular: Gebelerin labaratuar bulgularının ortalaması sırasıyla hemoglobin 11,3 g/dl,ferritin 15,1 ng/ml,vitamin B12 179,5 pg/ml, demir 57,1 mcg/dl, folik asit 10 ng/ml, 25 hidroksi D(25 OH D) vitamin 6,6 ng/ml’dir. Gebelik komplikasyonlarına bakıldığında ; %19,3’ünde oligohidramnios, %3’ünde gebelik haftasına göre düşük doğum ağırlığı , %2’sinde anhidramnios, %1,5’inde intrauterin büyüme kısıtlılığı, %1,5’inde makrozomik fetus, %0,5’inde polihidramnios ve %0,5’inde ablasyo plasenta görülmüştür. Yenidoğanların %55,9’u erkek, doğum ağırlığı ortalaması 3096 gr, boy ortalaması 48,9 cm idi. Yenidoğanların üçünde polisitemi tespit edildi.Yenidoğanlarda görülen anomaliler nöral tüp defekti (n=1), hipoplastik sol kalp sendromu(n=1), duodenal atrezi(n=1), hidrosel(n=1), ambigus genitale(n=1),anensefali(n=1), fasial paralizi(n=1) ve özofagus atrezi(n=1) idi. Hastaların gebelik sayısı arttıkça hemoglobin, ferritin ve folik asit değerlerinin referans değerlerine göre anlamlı olarak azaldığı (sırasıyla p=0.036,p=0.012,p=0.044), demir değeri düşük olanların 1. ve 5. dakika Apgar skorunun anlamlı olarak daha düşük olduğu saptanmıştır(sırasıyla p=0.000, p=0.002).25 OH D vitamin değeri ile ultrasonla ölçülen femur uzunluğu ve doğum boyu arasında anlamlı pozitif korelasyon olduğu tespit edilmiştir(sırasıyla p=0,020, p=0,050). Sonuç: Yetersiz beslenme ve aşırı beslenme olumsuz gebelik sonuçları ile ilişkili olabilir iken gebelik sırasında makrobesinlerin ve mikrobesinlerin yeterli alımı olumlu etki etmektedir.
{"title":"Evaluation of Maternal and Neonatal Outcomes of Pregnant Syrian Refugees Not Receiving Antenatal Care","authors":"Dilek MENEKŞE BEŞER, B. Seven, T. Küçüközkan","doi":"10.38136/jgon.1240950","DOIUrl":"https://doi.org/10.38136/jgon.1240950","url":null,"abstract":"Amaç: Antenatal bakıma ulaşamayan sığınmacı gebelerin maternal ve neonatal sonuçlarının değerlendirilmesi amaçlanmıştır. \u0000Gereç ve Yöntem: Bu çalışmada bir eğitim ve araştıma hastanesi doğum salonuna Ocak 2013-Ocak 2015 tarihleri arasında yatrılan ve gebeliği boyunca takip almayan 202 sığınmacı gebe dahil edildi. Çalışma etik kurul tarafından onaylandı. Suriyeli sığınmacı gebelerin maternal ve neonatal sonuçları değerlendirildi. \u0000Bulgular: Gebelerin labaratuar bulgularının ortalaması sırasıyla hemoglobin 11,3 g/dl,ferritin 15,1 ng/ml,vitamin B12 179,5 pg/ml, demir 57,1 mcg/dl, folik asit 10 ng/ml, 25 hidroksi D(25 OH D) vitamin 6,6 ng/ml’dir. Gebelik komplikasyonlarına bakıldığında ; %19,3’ünde oligohidramnios, %3’ünde gebelik haftasına göre düşük doğum ağırlığı , %2’sinde anhidramnios, %1,5’inde intrauterin büyüme kısıtlılığı, %1,5’inde makrozomik fetus, %0,5’inde polihidramnios ve %0,5’inde ablasyo plasenta görülmüştür. Yenidoğanların %55,9’u erkek, doğum ağırlığı ortalaması 3096 gr, boy ortalaması 48,9 cm idi. Yenidoğanların üçünde polisitemi tespit edildi.Yenidoğanlarda görülen anomaliler nöral tüp defekti (n=1), hipoplastik sol kalp sendromu(n=1), duodenal atrezi(n=1), hidrosel(n=1), ambigus genitale(n=1),anensefali(n=1), fasial paralizi(n=1) ve özofagus atrezi(n=1) idi. Hastaların gebelik sayısı arttıkça hemoglobin, ferritin ve folik asit değerlerinin referans değerlerine göre anlamlı olarak azaldığı (sırasıyla p=0.036,p=0.012,p=0.044), demir değeri düşük olanların 1. ve 5. dakika Apgar skorunun anlamlı olarak daha düşük olduğu saptanmıştır(sırasıyla p=0.000, p=0.002).25 OH D vitamin değeri ile ultrasonla ölçülen femur uzunluğu ve doğum boyu arasında anlamlı pozitif korelasyon olduğu tespit edilmiştir(sırasıyla p=0,020, p=0,050). \u0000Sonuç: Yetersiz beslenme ve aşırı beslenme olumsuz gebelik sonuçları ile ilişkili olabilir iken gebelik sırasında makrobesinlerin ve mikrobesinlerin yeterli alımı olumlu etki etmektedir.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130131590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. A. Oskovi Kaplan, A. S. ÖZGÜ-ERDİNÇ, G. Buyuk, Eda Üreyen Özdemir, C. Tayman, B. Dinç, Özlem Moraloğlu Tekin
Studies evaluating the safety and efficacy of currently available vaccines for SARS-CoV-2 do not include pregnant women and newborns. Safety data for vaccinating pregnant women with the COVID-19 vaccine is urgently needed since the vaccine is the only way to protect the vulnerable population. The 33 years-old pregnant women, a healthcare worker as an obstetrician and gynecologist, was vaccinated with inactivated SARS-CoV-2 vaccine with two doses within 28 days apart as the recommended protocol, on her 29th week and 33rd week of pregnancy. The rest of the pregnancy was uneventful and she gave birth on the 38th week to a healthy infant. The infant was a healthy boy upon first evaluation. Maternal blood was sampled immediately after birth, cord blood was obtained from a neonate for the immunoglobulin testing method. COVID-19 IgG and IgM antibodies for spike antigen was reported maternal as 2.04 (reactive) and the cord blood as 1.36 (reactive in a low titration). In this case we report an infant with SARS-CoV-2 IgG and IgM antibodies detectable in cord blood after maternal vaccination with inactivated vaccine.
{"title":"Neonatal antibodies are detected in cord blood after vaccination of pregnant woman with the inactivated SARS-CoV-2 vaccine: A case report","authors":"Z. A. Oskovi Kaplan, A. S. ÖZGÜ-ERDİNÇ, G. Buyuk, Eda Üreyen Özdemir, C. Tayman, B. Dinç, Özlem Moraloğlu Tekin","doi":"10.38136/jgon.1083930","DOIUrl":"https://doi.org/10.38136/jgon.1083930","url":null,"abstract":"Studies evaluating the safety and efficacy of currently available vaccines for SARS-CoV-2 do not include pregnant women and newborns. Safety data for vaccinating pregnant women with the COVID-19 vaccine is urgently needed since the vaccine is the only way to protect the vulnerable population. The 33 years-old pregnant women, a healthcare worker as an obstetrician and gynecologist, was vaccinated with inactivated SARS-CoV-2 vaccine with two doses within 28 days apart as the recommended protocol, on her 29th week and 33rd week of pregnancy. The rest of the pregnancy was uneventful and she gave birth on the 38th week to a healthy infant. The infant was a healthy boy upon first evaluation. Maternal blood was sampled immediately after birth, cord blood was obtained from a neonate for the immunoglobulin testing method. COVID-19 IgG and IgM antibodies for spike antigen was reported maternal as 2.04 (reactive) and the cord blood as 1.36 (reactive in a low titration). In this case we report an infant with SARS-CoV-2 IgG and IgM antibodies detectable in cord blood after maternal vaccination with inactivated vaccine.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132792802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Ünsal, Uğurcan Zorlu, Pelin Ünsal, Nur Karaaslan, N. Özcan, T. Turan
Özet Amaç: Jinekolojik kanserler nedeniyle opere edilen hastalarda, hastaların operasyon öncesinde kullandığı ilaç sayısı ve potansiyel uygunsuz ilaç kullanımının yoğun bakım yatış süresiyle ilişkili olup olmadığını değerlendirmektir. Gereçler ve Yöntem: Çalışmaya 2020 Haziran ve 2022 Aralık tarihleri arasında Ankara Bilkent Şehir Hastanesi Jinekolojik Onkoloji Cerrahisi Kliniği’nde endometrium, over, serviks ve diğer jinekolojik kanserler nedeniyle opere edilen ve operasyon sonrasında en az 24 saat yoğun bakımda takip edilen hastalar, retrospektif olarak dahil edilmiştir. Polifarmasi, 5 ve üzerinde ilaç kullanımı olarak tanımlanmıştır. Uygunsuz ilaç kullanımı için Türkiye Yaşlıda Uygunsuz İlaç Kullanım Kriterleri (TIME-to-STOP, TIME-to-START) kullanılmıştır. Bulgular: Çalışmaya toplam 253 hasta dahil edilmiştir. 220 (%87) hasta endometrium kanseri, 25 (%9.9) hasta over kanseri, 2 (%0.8) hasta serviks kanseri, 6 (%2.4) hastada diğer jinekolojik kanserler nedeniyle opere edilip yoğun bakımda postoperatif takip edilmiştir. Hastalar postoperatif dönemde yoğun bakımda 2 gün (aralık; 1-21 gün) takip edilmiştir. Polifarmasi 34 (%13.4) hastada, potansiyel uygunsuz ilaç kullanımı ise 83 (%32.8) hastada bulunmuştur. Yoğun bakım yatış süresi ve ilaç sayısı arasında pozitif bir korelasyon izlenmiştir (r=0.142; p=0.024). Çok değişkenli regresyon analizinde, ilaç sayısı (OR:1.228 %95 CI:1.034-1.460, p=0.020) diğer tüm nedenlerden bağımsız olarak yoğun bakımda yatış süresiyle ilişkili bulunmuştur. Sonuç: Jinekolojik kanserler nedeniyle opere edilen ve post operatif dönemde yoğun bakımda takip edilen hastalarda, polifarmasi yatış süresiyle ilişkilidir. Hastaların yoğun bakım kalış sürelerini ön görmek için her hastada, hastaların yatış öncesi ko-morbiditeleri ve ilaç kullanımlarını değerlendirmek anahtar noktalardan biridir.
{"title":"IS POLYPHARMACY RELATED TO THE INTENSIVE CARE UNIT LENGTH OF STAY IN PATIENTS WHO HAVE BEEN OPERATED ON DUE TO GYNECOLOGICAL CANCERS?","authors":"Mehmet Ünsal, Uğurcan Zorlu, Pelin Ünsal, Nur Karaaslan, N. Özcan, T. Turan","doi":"10.38136/jgon.1279562","DOIUrl":"https://doi.org/10.38136/jgon.1279562","url":null,"abstract":"Özet \u0000Amaç: Jinekolojik kanserler nedeniyle opere edilen hastalarda, hastaların operasyon öncesinde kullandığı ilaç sayısı ve potansiyel uygunsuz ilaç kullanımının yoğun bakım yatış süresiyle ilişkili olup olmadığını değerlendirmektir. \u0000Gereçler ve Yöntem: Çalışmaya 2020 Haziran ve 2022 Aralık tarihleri arasında Ankara Bilkent Şehir Hastanesi Jinekolojik Onkoloji Cerrahisi Kliniği’nde endometrium, over, serviks ve diğer jinekolojik kanserler nedeniyle opere edilen ve operasyon sonrasında en az 24 saat yoğun bakımda takip edilen hastalar, retrospektif olarak dahil edilmiştir. Polifarmasi, 5 ve üzerinde ilaç kullanımı olarak tanımlanmıştır. Uygunsuz ilaç kullanımı için Türkiye Yaşlıda Uygunsuz İlaç Kullanım Kriterleri (TIME-to-STOP, TIME-to-START) kullanılmıştır. \u0000Bulgular: Çalışmaya toplam 253 hasta dahil edilmiştir. 220 (%87) hasta endometrium kanseri, 25 (%9.9) hasta over kanseri, 2 (%0.8) hasta serviks kanseri, 6 (%2.4) hastada diğer jinekolojik kanserler nedeniyle opere edilip yoğun bakımda postoperatif takip edilmiştir. Hastalar postoperatif dönemde yoğun bakımda 2 gün (aralık; 1-21 gün) takip edilmiştir. Polifarmasi 34 (%13.4) hastada, potansiyel uygunsuz ilaç kullanımı ise 83 (%32.8) hastada bulunmuştur. Yoğun bakım yatış süresi ve ilaç sayısı arasında pozitif bir korelasyon izlenmiştir (r=0.142; p=0.024). Çok değişkenli regresyon analizinde, ilaç sayısı (OR:1.228 %95 CI:1.034-1.460, p=0.020) diğer tüm nedenlerden bağımsız olarak yoğun bakımda yatış süresiyle ilişkili bulunmuştur. \u0000 \u0000Sonuç: Jinekolojik kanserler nedeniyle opere edilen ve post operatif dönemde yoğun bakımda takip edilen hastalarda, polifarmasi yatış süresiyle ilişkilidir. Hastaların yoğun bakım kalış sürelerini ön görmek için her hastada, hastaların yatış öncesi ko-morbiditeleri ve ilaç kullanımlarını değerlendirmek anahtar noktalardan biridir.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124665356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Refika SİRMA DOKUZBOY, Fatma Nur Sari, E. Çakar, Şehribanu Işik, A. Yazici, Evrim ALYAMAC DİZDAR
In this article, we aim to represent a neonatal fatal case of CHARGE syndrome and make a mini-review of the literature to underline the wide range of congenital abnormalities and clinical symptoms of individuals with CHARGE syndrome face early in life. This patient, with his characteristic dysmorphic features, congenital heart defects, and severe feeding intolerance, is a good example of how complex the syndrome could be. CHARGE syndrome might affect numerous organ systems and result in severe early lethal cases for some, while some of the cases show a very mild phenotypic spectrum and may go unrecognized.
{"title":"Fatal Seyirli Bir Neonatal CHARGE Sendromu Olgusu ve Kısa Literatür Taraması","authors":"Refika SİRMA DOKUZBOY, Fatma Nur Sari, E. Çakar, Şehribanu Işik, A. Yazici, Evrim ALYAMAC DİZDAR","doi":"10.38136/jgon.1037244","DOIUrl":"https://doi.org/10.38136/jgon.1037244","url":null,"abstract":"In this article, we aim to represent a neonatal fatal case of CHARGE syndrome and make a mini-review of the literature to underline the wide range of congenital abnormalities and clinical symptoms of individuals with CHARGE syndrome face early in life. This patient, with his characteristic dysmorphic features, congenital heart defects, and severe feeding intolerance, is a good example of how complex the syndrome could be. CHARGE syndrome might affect numerous organ systems and result in severe early lethal cases for some, while some of the cases show a very mild phenotypic spectrum and may go unrecognized.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126618779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eda ÜREYEN ÖZDEMİR, Gul Nihal Buyuk, H. Keski̇n, Özlem MORALOĞLU TEKİN, A. S. ÖZGÜ-ERDİNÇ
Aim: To show the change in the rates of vaginal delivery and cesarean section during the Covid-19 Pandemic in Ankara City Hospital. Materials and Method: This cross-sectional study included pregnant women who gave birth between 37 and 42 gestational weeks. Cesarean birth rates for each of the 10 Robson categories, compared between Covid-19 and before Covid-19 groups. Results: 21366 pregnant women were included in the study. The cesarean section rates were examined by dividing the patients who gave birth during covid -19 into two groups those who were infected with covid and those who were not. During the Covid-19 pandemic, women with previous CS (Robson group 5) and the nulliparous women who had spontaneous labor with a cephalic presentation at term (Robson group 1) were the most common contributors to the global CS rate, 21,68% and 6.5%, respectively regardless of being infected with Covid-19. Similarly, Robson group 5 makes the greatest contribution to the overall cesarean section rate (% 21,68) when we evaluate the patients by separating them as covid positive and covid negative. Conclusion: At the beginning of the epidemic higher rates of cesarean section are expected in the group of pregnant women with Covid-19 infection due to our limited knowledge. Although the mother's infection complicates the delivery, the timing and mode of delivery should be individualized according to the clinical condition of the pregnant woman, the week of gestation, and the condition of the fetus.
{"title":"Covid-19 Pandemisi Sırasında Doğum Şeklinin Robson Sınıflandırma Sistemine Göre Değerlendirilmesi","authors":"Eda ÜREYEN ÖZDEMİR, Gul Nihal Buyuk, H. Keski̇n, Özlem MORALOĞLU TEKİN, A. S. ÖZGÜ-ERDİNÇ","doi":"10.38136/jgon.1262571","DOIUrl":"https://doi.org/10.38136/jgon.1262571","url":null,"abstract":"Aim: To show the change in the rates of vaginal delivery and cesarean section during the Covid-19 Pandemic in Ankara City Hospital. Materials and Method: This cross-sectional study included pregnant women who gave birth between 37 and 42 gestational weeks. Cesarean birth rates for each of the 10 Robson categories, compared between Covid-19 and before Covid-19 groups. Results: 21366 pregnant women were included in the study. The cesarean section rates were examined by dividing the patients who gave birth during covid -19 into two groups those who were infected with covid and those who were not. During the Covid-19 pandemic, women with previous CS (Robson group 5) and the nulliparous women who had spontaneous labor with a cephalic presentation at term (Robson group 1) were the most common contributors to the global CS rate, 21,68% and 6.5%, respectively regardless of being infected with Covid-19. Similarly, Robson group 5 makes the greatest contribution to the overall cesarean section rate (% 21,68) when we evaluate the patients by separating them as covid positive and covid negative. Conclusion: At the beginning of the epidemic higher rates of cesarean section are expected in the group of pregnant women with Covid-19 infection due to our limited knowledge. Although the mother's infection complicates the delivery, the timing and mode of delivery should be individualized according to the clinical condition of the pregnant woman, the week of gestation, and the condition of the fetus.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130028690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract: Objective: COVID-19 has caused a rapid transformation in the healthcare system, including in particular, the care of vulnerable cancer patients. The aim of this study was to present our clinical experience in gynecological cancer surgeries in a COVID-19-free cancer hospital during the pandemic. Methods: A retrospective analysis was made of the data of patients with ovarian, endometrium, cervix and vulva cancers who were treated with surgery between March 2020 and March 2021, with particular focus on the complication rates on day 30, and at the end of one year. Results: The study included a total of 74 patients with mean age of 59 years. The most common diagnosis was ovarian cancer (48.6%) followed by endometrial (43.2%), cervical (6.8%) and vulvar cancer (1.4%). Most of the patients were in advanced stage (FIGO 3 and 4) of ovarian (86%), endometrial (59.4%) and cervical local advanced (60%) cancer. The complication rate was 17.6 %. Surgery was delayed in one patient with a preoperative positive polymerase chain reaction (PCR) test for COVID-19 infection, and none of the patients had a positive test result in the early postoperative period. Conclusion: COVID-19-free institutions for cancer surgery, is an effective treatment strategy in the context of the pandemic. The results of this study indicate that continuity of cancer treatment can be achieved safely, with strict adherence to COVID-19 precautions for both patients and healthcare workers. Keywords: COVID-19, gynecological cancer, surgery, treatment
{"title":"Analysis of the Gynecologic Cancer Surgery with Pre-pandemic Protocols in a COVID-19 Free Cancer Center Gynecologic Cancer Surgery in COVID-19 Free Center","authors":"F. Atalay, Zehra ÖZTÜRK BAŞARIR","doi":"10.38136/jgon.1217870","DOIUrl":"https://doi.org/10.38136/jgon.1217870","url":null,"abstract":"Abstract: \u0000Objective: COVID-19 has caused a rapid transformation in the healthcare system, including in particular, the care of vulnerable cancer patients. The aim of this study was to present our clinical experience in gynecological cancer surgeries in a COVID-19-free cancer hospital during the pandemic. \u0000 \u0000Methods: A retrospective analysis was made of the data of patients with ovarian, endometrium, cervix and vulva cancers who were treated with surgery between March 2020 and March 2021, with particular focus on the complication rates on day 30, and at the end of one year. \u0000 \u0000Results: The study included a total of 74 patients with mean age of 59 years. The most common diagnosis was ovarian cancer (48.6%) followed by endometrial (43.2%), cervical (6.8%) and vulvar cancer (1.4%). Most of the patients were in advanced stage (FIGO 3 and 4) of ovarian (86%), endometrial (59.4%) and cervical local advanced (60%) cancer. The complication rate was 17.6 %. Surgery was delayed in one patient with a preoperative positive polymerase chain reaction (PCR) test for COVID-19 infection, and none of the patients had a positive test result in the early postoperative period. \u0000 \u0000Conclusion: COVID-19-free institutions for cancer surgery, is an effective treatment strategy in the context of the pandemic. The results of this study indicate that continuity of cancer treatment can be achieved safely, with strict adherence to COVID-19 precautions for both patients and healthcare workers. \u0000 \u0000Keywords: COVID-19, gynecological cancer, surgery, treatment","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124433850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction Anatomy, physiology, and flora of the female genital system change due to pregnancy-related hormonal, metabolic, endocrinological, and immunological reasons. Dysbiosis increases the risk of spontaneous preterm birth with chronic inflammatory processes by causing infections in the fetoplacental unit by the ascending or hematogenous route. Our study aimed to reveal the bad personal habits and practices predispose to vaginitis, create resistance to treatment, and cause recurrences in pregnant women with vaginitis. Material-Methods Our descriptive study was conducted on a group of patients who applied to the Department of Obstetrics and Gynecology, between December 2021 and April 2022, with the ethics committee's approval. Our study group consists of 178 pregnant women over 18 who are literate, cooperative, and volunteered to answer all the questions in the questionnaire. Results Vaginal douching in 71.9% (128 people) of the participants, not ironing their underwear at all in 67.4% (120 people), cleaning the perineum from back to front in 66.9% (119 people), 61.2% daily pad use in 61.2% (109 people), synthetic laundry use in 41% (73 people), use of genital cleaning products in 16.3% (29 people), hand washing underwear in 7.3% (13 people) and 5.6% (10 people) had frequent sexual intercourse behavior. Regarding genital area cleaning, 11.2% (20 people) of the patients knew about using white vinegar, and 3.4% (6 people) used the acidic mixture. 6.7% (12 people) of the participants knew the use of vaginal probiotics. Conclusion Considering the results of our study, it can be said that wrong practices regarding genital hygiene continue, especially in women from low socio-economic and cultural levels. In this respect, the women need training on genital hygiene as a preventive measure due to the mistakes they make in practice related to genital hygiene and the possibility of experiencing a genital infection in a significant part of them. In conclusion, considering that the most significant deficiency in the occurrence of genital infections in women is the lack of education, it is recommended that all health professionals develop a training plan to prevent genital infections and apply it to women in the regions they work.
{"title":"Factors Affecting The Success Of Vaginitis Treatment In Pregnant Women ; A Prospective Cohort Study","authors":"M. Canday, A. Yurtkal","doi":"10.38136/jgon.1136075","DOIUrl":"https://doi.org/10.38136/jgon.1136075","url":null,"abstract":"Introduction \u0000Anatomy, physiology, and flora of the female genital system change due to pregnancy-related hormonal, metabolic, endocrinological, and immunological reasons. Dysbiosis increases the risk of spontaneous preterm birth with chronic inflammatory processes by causing infections in the fetoplacental unit by the ascending or hematogenous route. \u0000Our study aimed to reveal the bad personal habits and practices predispose to vaginitis, create resistance to treatment, and cause recurrences in pregnant women with vaginitis. \u0000 \u0000Material-Methods \u0000Our descriptive study was conducted on a group of patients who applied to the Department of Obstetrics and Gynecology, between December 2021 and April 2022, with the ethics committee's approval. Our study group consists of 178 pregnant women over 18 who are literate, cooperative, and volunteered to answer all the questions in the questionnaire. \u0000 \u0000Results \u0000Vaginal douching in 71.9% (128 people) of the participants, not ironing their underwear at all in 67.4% (120 people), cleaning the perineum from back to front in 66.9% (119 people), 61.2% daily pad use in 61.2% (109 people), synthetic laundry use in 41% (73 people), use of genital cleaning products in 16.3% (29 people), hand washing underwear in 7.3% (13 people) and 5.6% (10 people) had frequent sexual intercourse behavior. Regarding genital area cleaning, 11.2% (20 people) of the patients knew about using white vinegar, and 3.4% (6 people) used the acidic mixture. 6.7% (12 people) of the participants knew the use of vaginal probiotics. \u0000Conclusion \u0000Considering the results of our study, it can be said that wrong practices regarding genital hygiene continue, especially in women from low socio-economic and cultural levels. \u0000In this respect, the women need training on genital hygiene as a preventive measure due to the mistakes they make in practice related to genital hygiene and the possibility of experiencing a genital infection in a significant part of them. \u0000In conclusion, considering that the most significant deficiency in the occurrence of genital infections in women is the lack of education, it is recommended that all health professionals develop a training plan to prevent genital infections and apply it to women in the regions they work.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"618 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133058571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: To evaluate the variability of anti-Mullerian hormone (AMH) and antral follicle count (AFC) in an unstimulated menstrual cycle. Materials and Method: The study was designed on 50 women who had regular menstrual cycles and did not have any systemic disease or previous ovarian surgery. Serum AMH levels and antral follicle counts of all participants were evaluated three times in the same menstrual cycle in the early and late follicular phase and luteal phase. To evaluate the intracyclic AMH fluctuation according to age, participants were divided into two groups; younger (
{"title":"Variability of serum anti-Mullerian hormone level and antral follicle count in an unstimulated menstrual cycle","authors":"Merve Dizdar, I. Kale, İlgi Esen, R. Bayık","doi":"10.38136/jgon.1162167","DOIUrl":"https://doi.org/10.38136/jgon.1162167","url":null,"abstract":"Aim: To evaluate the variability of anti-Mullerian hormone (AMH) and antral follicle count (AFC) in an unstimulated menstrual cycle. \u0000Materials and Method: The study was designed on 50 women who had regular menstrual cycles and did not have any systemic disease or previous ovarian surgery. Serum AMH levels and antral follicle counts of all participants were evaluated three times in the same menstrual cycle in the early and late follicular phase and luteal phase. To evaluate the intracyclic AMH fluctuation according to age, participants were divided into two groups; younger (","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131051435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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