European Journal of Dentistry最新文献

Objective:  The aim of this study was to assess the color stability of two microhybrid composite resins after immersion in different coloring solutions for 4 weeks.

Materials and methods:  Sixty disc-shaped samples (2 mm in thickness and 10 mm in diameter) were prepared according to ISO standard 4049. Two composite resins were used: Filtek Z350 XT (3M ESPE) and Harvard Restore (Harvard Dental International GmbH). After initial color measurements, five samples of each resin were immersed in artificial saliva, Turkish coffee, lemonade, black tea, Coca-Cola 0%, and green tea for 4 weeks. The spectrophotometric measurements were carried out after 24 hours of immersion in the various solutions and then weekly, using a VITA Easyshade Advance 4.0 spectrophotometer (CIE L*a*b* system). Statistical analysis was carried out with SPSS 25.0 software.

Results:  The two composite resins tested revealed discoloration after immersion in all the drinks at a variable immersion period showing different color behaviors. The one-way analysis of variance showed a significant difference in the values of brightness (L), in chromaticity from green to red (a), in chromaticity from blue to yellow (b), and in the color (ΔE) of the two materials at different time intervals. The greatest color change in all the groups was caused by coffee followed by lemonade and black tea followed by green tea, Coca-Cola 0%, and artificial saliva.

Clinical significance:  The importance of color stability of dental restorations is crucial for dental professionals and patients. Indeed, the quality of a restoration is considered from both a functional and esthetic points of view. The information obtained from this study should prove useful for clinicians to make informed decisions in selecting the best materials for their patients' esthetic restorations.

Conclusion:  The Harvard Restore showed a better colorimetric behavior compared with the Filtek Z350. Coffee, black tea, and green tea had the most marked effects on the discoloration of composites, especially on Filtek Z350. Coca-Cola 0% showed a similar behavior to artificial saliva.

Objective:  Intraoral radiographs are used in periodontal therapy to understand interdental bony health and defects. However, identifying three-wall bony defects is challenging due to their variations. Therefore, this study aimed to classify three-wall intrabony defects using deep learning-based convolutional neural network (CNN) models to distinguish between three-wall and non-three-wall bony defects via intraoral radiographs.

Materials and methods:  A total of 1,369 radiographs were obtained from 556 patients who had undergone periodontal surgery. These radiographs, each featuring at least one area of intrabony defect, were categorized into 15 datasets based on the presence of three-wall or non-three-wall intrabony defects. We then trained six CNN models-InceptionV3, InceptionResNetV2, ResNet50V2, MobileNetV3Large, EfficientNetV2B1, and VGG19-using these datasets. Model performance was assessed based on the area under curve (AUC), with an AUC value ≥ 0.7 considered acceptable. Various metrics were thoroughly examined, including accuracy, precision, recall, specificity, negative predictive value (NPV), and F1 score.

Results:  In datasets excluding circumferential defects from bitewing radiographs, InceptionResNetV2, ResNet50V2, MobileNetV3Large, and VGG19 achieved AUC values of 0.70, 0.73, 0.77, and 0.75, respectively. Among these models, the VGG19 model exhibited the best performance, with an accuracy of 0.75, precision of 0.78, recall of 0.82, specificity of 0.67, NPV of 0.88, and an F1 score of 0.75.

Conclusion:  The CNN models used in the study showed an AUC value of 0.7 to 0.77 for classifying three-wall intrabony defects. These values demonstrate the potential clinical application of this approach for periodontal examination, diagnosis, and treatment planning for periodontal surgery.

Objectives:  This study aims to examine the effects of silver diamine fluoride and potassium iodide (SDF/KI) treatment on the possible color changes and the microtensile bond strength of composite restorations to carious dentin in different dentitions.

Material and methods:  A total of 48 sound human teeth were utilized in this study. Twenty-four primary molar teeth were divided into two groups. Each group has 12 teeth; group 1 received no pretreatment, while group 2 received SDF/KI treatment. Also, 24 permanent premolar teeth were divided into two groups. Group 3 received no pretreatment, and group 4 received SDF/KI treatment. For 7 days at 25 °C, every sample was submerged in a demineralizing solution. Following the manufacturer's guidelines for SDF/KI treatments, exposed dentin surfaces were promptly preserved in artificial saliva (pH 7.4) for 14 days. On the prepared teeth surfaces of the nontreated groups, deionized water was administered rather than SDF/KI. A self-etching bonding agent was used, and a 4-mm-thick composite restoration was constructed. Evaluations were conducted on color measurement, microtensile bond strength, and mode of failure.

Statistical analysis:  The groups were compared using a one-way analysis of variance test, and a post hoc test was used for pairwise comparisons.

Result:  Regarding color measurement, in deciduous dentition, there were no statistically significant differences between the groups. Additionally, there is no discernible variation in ΔE values among various pretreatment groups in the permanent dentition. Microtensile bond strength did not differ significantly between permanent and deciduous teeth.

Conclusion:  A 14-day delay in the application of composite restoration can successfully conceal the color of SDF/KI without compromising the microtensile bond strength.

When vertical bone loss results in insufficient crestal height to place standard-length implants without the use of osseous grafting, this poses clinical issues to implant usage. Based on an analysis of the literature and clinical experience, it has been found that it is possible to optimally use the available bone volume of the maxillary and mandibular ridges for implant placement without extensive osseous grafting to increase vertical height. This case report will examine several uses of ultrashort implants utilizing the Bicon system in common clinical situations in the maxillary and mandibular arches without the need for osseous reconstruction to improve the available vertical height of the crest to permit implant placement.

Objectives:  Guided tissue regeneration (GTR) is a widely used technique in contemporary dentistry which helps achieve regeneration of periodontal tissues. This study aims to identify leading countries, authors, institutes, journals, scientific publications, and mostly used keyword regarding role of GTR in treatment for periodontal disease using the Scopus database.

Materials and methods:  A well-curated search through Scopus database for significant literature related to GTR published between 1987 and 2023 was performed. Bibliographical data which comprised of abstracts, title, keywords, references, citations, and other relevant information were composed. The data was analyzed using MS Excel and VOSviewer.

Results:  Scientific literature on GTR was manually scrutinized, and 308 paper were analyzed using the Scopus database. The first paper on GTR was published in 1987. Journal of Periodontology was identified as the leading journal, while the United States and Italy were the top contributing countries. University of Sienna was the most productive organization. Roberto Pontoriero was identified as the highly cited author. A highly cited scientific paper was published by Pintippa Bunyaratavej in 2001.

Conclusion:  The present bibliometric study gives useful information related to the total number of scientific articles published from 1987 to 2023. A rising trend of scientific publication was identified which continued followed by a notable decline after 2004. The analysis also recognized the United States and University of Sienna, from Italy as most active country and organizations, while the Journal of Periodontology as the leading journal.

Clinical relevance:  This study may assist in continuing education and evidence-based practice for clinicians and new researchers by providing knowledge and aiding literature searches in the domain of GTR used in treatment for periodontal conditions.

Objectives:  Fabrication processes affect accuracy of restoration. This study compared marginal accuracy of ceramic veneer metal upon different metal substructure fabrication techniques, ceramic veneering methods, stages, and sites of restoration.

Material and methods:  A prepared premolar metal abutment was used to fabricate 96 metal substructures from 4 techniques: cast metal with traditionally impressed tooth (CmTt), cast metal with digitally milled wax (CmDw), sintered metal with digitally impressed tooth (SmDt), and sintered metal with digitally impressed stone model (SmDm). As-cast (A) substructures were degassed (D), opaqued (O), and contoured (C) with porcelain layering (Pl) or press-on (Pp) methods and glazed (G). Marginal fit was measured at A, D, O, C, and G stages, on buccal (Bu), lingual (Li), mesial (Me), and distal (Di) sites using silicone replica.

Statistical analysis:  Analysis of variance and Bonferroni test were analyzed for significant differences of marginal fit upon different factors (α = 0.05).

Results:  Significantly different accuracy was found upon metal substructures fabrication technique, veneering methods, stages, and sites of restoration (p < 0.05). SmDt and SmDm revealed significantly better accuracy than CmTt and CmDw (p < 0.05). Pp generated significantly better accuracy than Pl (p < 0.05). Significant increasing inaccuracy was found at D stage (p < 0.05). Me and Di sites exhibited larger inaccuracy than Bu and Li sites (p < 0.05). However, marginal inaccuracy for all groups was under clinically acceptable marginal fit.

Conclusions:  Increasing marginal inaccuracies upon stages of fabrication were noticed, with highly observed at the proximal site. Sintered metal provided better accuracy than cast metal, while press-on veneering generated better accuracy than the layering method. Porcelain press-on sintered metal was suggested for fabrication restoration.

This review aims to provide an overall picture of the three-dimensional (3D) printing contributions to endodontic practice in treatment planning and execution. The methodology entails a comprehensive literature review of the technological processes and 3D printing applications in the field. Some key findings show that 3D printing is highly effective in producing the right dental models for training, helps in complex surgeries, and supports the transition toward personalized therapies. The review reveals that 3D printing has many benefits but that the broader adoption of this technology faces issues, including high technical requirements, high costs, and the need for safety standards. The study concludes that although in the future some challenges need to be addressed, the potential of 3D printing in endodontics is enormous and this means that the treatment methods of dentistry could be more efficient and innovative.

Objectives:  To investigate the association of E-cadherin single nucleotide polymorphisms (SNPs) with periodontitis and the potential of these SNPs for identifying susceptibility to periodontitis.

Materials and methods:  Periodontal clinical parameters were recorded followed by collecting venous blood for DNA extraction. Polymerase chain reaction was used to amplify target segments of the E-cadherin gene. Determination of the genotype and allele frequencies was performed using Sanger sequencing. All statistical analyses were performed using GraphPad Prism (version 9) using a statistically significant difference of p < 0.05.

Results:  A total of 207 participants were recruited into two groups of healthy controls (n = 105) and cases diagnosed with periodontitis stage 2 or 3, grade B or C (n = 102). Analyses indicated that the genotypes and alleles of rs3743674 and rs5030625 E-cadherin SNPs were significantly associated with periodontitis. Results from a binary regression model suggested that the presence of these SNPs may indicate susceptibility to periodontitis and increase the rate of progression. Linkage disequilibrium analysis indicated that E-cadherin variants rs3743674 and rs5030625, and rs10272115 and rs16260 were correlated in a nonrandom manner (r ² = 0.638 and 0.495, respectively).

Conclusion:  E-cadherin gene variants, rs3743674 and rs5030625, were associated with the periodontitis phenotype. These biomarkers may identify individuals susceptible to periodontitis and the rate of disease progression.

Objectives:  Pulp capping is a pivotal treatment in dentistry aimed at preserving pulp vitality. While calcium hydroxide has long been considered the gold standard in pulp capping materials, its long-term use can induce chronic inflammation, ultimately leading to pulp necrosis and affecting human health. In this context, ellagic acid, a natural compound with potent anti-inflammatory properties, emerged as a promising adjunct to mitigate inflammation associated with calcium hydroxide application, thereby sustaining pulp vitality. This study aimed to investigate the inflammatory response by alterations in neutrophil, macrophage, lymphocyte, and tumor necrosis factor-α (TNF-α) expression following the treatment with a combination of calcium hydroxide and ellagic acid.

Materials and methods:  Dental pulp perforation was made on 27 male Wistar rats on the upper first molar and then pulp capped with calcium hydroxide and ellagic acid. The pulp of the control positive group was capped with calcium hydroxide, and the control group was not capped. The teeth were then extracted after 1, 3, and 7 days posttreatment. The differences in the number of neutrophils, macrophages, lymphocytes, and TNF-α expression were analyzed using one-way analysis of variance (ANOVA) and Tukey's honestly significant difference (HSD) test.

Results: The treatment combination of calcium hydroxide and ellagic acid showed the lowest neutrophil number and TNF-α expression compared with the other groups (p < 0.05), while the macrophage and lymphocyte numbers were the highest compared with the other groups (p < 0.05).

Conclusion:  The combination of calcium hydroxide and ellagic acid as a pulp capping material exhibited a dual effect on the inflammatory response in dental pulp. These findings suggest that calcium hydroxide and ellagic acid modulate the inflammatory response in a complex manner, promoting a more controlled and potentially beneficial healing process.

Objective:  The aim of this randomized, controlled, split-mouth study was to compare full-mouth air polishing followed by ultrasonic debridement (known as Guided Biofilm Therapy [GBT]) versus traditional Scaling and Root Planing (SRP), in terms of pocket closure in patients with stages III and IV periodontitis.

Materials and methods:  The patients underwent periodontal therapy in two sessions. At the beginning of the first session, quadrants I and IV and II and III were randomly assigned to GBT or SRP treatment. Periodontal parameters were collected at baseline, 6 weeks (T1), and 3 months (T2) after therapy. The primary outcome was the number of experimental sites (pocket probing depth [PPD] >4 and <10 mm) becoming closed pockets (PPD ≤ 4 mm bleeding on probing [BOP] negative) at T1 and T2. Secondary outcomes were PPD, recession, clinical attachment level, BOP, and plaque index variations at the experimental sites and treatment time.

Statistical analysis:  A 10% difference in the primary outcome between the two protocols was set as the threshold to define inferiority/noninferiority of the test treatment. The primary outcome was modeled using a generalized estimating equation model to account for intrapatient measurement correlation. The estimates are reported as differences between groups' percentages (treatments or time points) and corresponding 95% confidence interval (95% CI). All analyses assumed a significance level of 5%.

Results:  A total of 32 patients were selected. Mean PPD (mm) reduced from 6.23 (6.06-6.40) to 3.33 (3.06-3.61) at T2 for GBT, and from 6.21 (6.04-6.38) to 3.32 (3.11-3.53) at T2 for SRP. Both treatments reached a comparable percentage of closed pockets at T1 (77.9% for GBT vs. 80.1% for SRP, p = 0.235) and T2 (84.1% for GBT vs. 84.4% for SRP, p = 0.878), with no statistically or clinically significant difference. GBT and traditional SRP with ultrasonic and hand instruments reach satisfactory clinical results in the active treatment of patients with stages III and IV periodontitis, with comparable rates of closed pockets and treatment time.

Conclusion:  GBT is a suitable option in the active phase of periodontitis management in patients with stages III and IV periodontitis.