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Pediatric lumbar spine MRI: structural imaging findings and anatomical variants associated with disc herniation. 小儿腰椎MRI:与椎间盘突出相关的结构成像结果和解剖变异。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-22 DOI: 10.1007/s00586-025-09691-2
Şükriye Yılmaz, Hasan Bulut, Muhammed Erkan Emrahoğlu

Background: This study aimed to evaluate the clinical indications, imaging findings, and structural factors identified on pediatric lumbar MRI, with a specific focus on non-traumatic low back pain and lumbar disc herniation (LDH).

Materials and methods: A retrospective review was conducted of 1,253 lumbar MRI examinations performed in pediatric patients aged 0-18 years between November 2022 and March 2024. Clinical indications were documented for all patients. Imaging findings were systematically analyzed in children presenting with non-traumatic low back pain. In patients diagnosed with LDH, the presence of lumbosacral transitional vertebrae (LSTV), spondylolysis, and spondylolisthesis was reassessed. LSTVs were categorized using the Castellvi classification.

Results: Low back pain was the most common indication for MRI (n=650, 51.9%). Among these children, 62.3% had normal examinations. Disc protrusion (15.1%), degenerative disc or endplate changes (8.9%), spondylolysis (5.5%), and spondylolisthesis (2.8%) were the most frequent abnormalities. LDH predominantly occurred at the L5-S1 level. LSTVs were identified in 52 patients (8%) with LDH, and higher-grade Castellvi types were significantly associated with LDH (p<0.001). Lumbarization of S1 was observed in 10 LDH patients, typically showing squaring of S1 and prominence of the S1-2 disc space.

Conclusion: Although most pediatric lumbar MRI examinations performed for low back pain are normal, MRI remains essential for identifying clinically relevant structural abnormalities. LDH is more common in older adolescents and is associated with anatomical variants such as LSTV and lumbarization. Recognition of these variations, combined with adherence to evidence-based imaging recommendations, is crucial for accurate diagnosis and appropriate clinical management in children with low back pain.

背景:本研究旨在评估儿童腰椎MRI的临床适应症、影像学表现和结构因素,特别关注非创伤性腰痛和腰椎间盘突出症(LDH)。材料和方法:回顾性分析了2022年11月至2024年3月期间0-18岁儿童患者进行的1253次腰椎MRI检查。记录了所有患者的临床适应症。系统分析了非创伤性腰痛患儿的影像学表现。在诊断为LDH的患者中,重新评估腰骶移行椎体(LSTV)、峡部裂和峡部滑脱的存在。使用Castellvi分类对lstv进行分类。结果:腰痛是MRI最常见的指征(n=650, 51.9%)。其中62.3%检查正常。椎间盘突出(15.1%)、退变性椎间盘或终板改变(8.9%)、峡部裂(5.5%)和峡部滑脱(2.8%)是最常见的异常。LDH主要发生在L5-S1水平。52例(8%)LDH患者中发现LSTVs,高级别Castellvi型与LDH显著相关(结论:尽管大多数儿童腰痛MRI检查正常,但MRI仍然是识别临床相关结构异常的必要条件。LDH在年龄较大的青少年中更为常见,并与LSTV和腰椎化等解剖变异有关。认识到这些差异,并遵循循证影像学建议,对于儿童腰痛的准确诊断和适当的临床治疗至关重要。
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引用次数: 0
Answer to Letter to the Editor of C. Lu, et al. concerning "Mortality for pneumonia and risk of pneumonia in children with cerebral palsy treated with and without surgery" by M. Ahonen, et al. (Eur Spine J [2025]; doi: 10.1007/s00586-025-09625-y). C. Lu, et al.关于M. Ahonen, et al.“脑瘫患儿肺炎死亡率和肺炎风险”的回复[J]; [2025]; doi: 10.1007/s00586-025-09625-y)。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-22 DOI: 10.1007/s00586-025-09701-3
Matti Ahonen, Ira Jeglinsky-Kankainen, Mika Gissler, Ilkka Helenius
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引用次数: 0
Analysis of root causes of adverse events with Mazor X and Mazor X stealth edition-guided spine surgeries: an FDA MAUDE database study. Mazor X和Mazor X隐形版引导脊柱手术不良事件的根本原因分析:FDA MAUDE数据库研究
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-22 DOI: 10.1007/s00586-025-09683-2
Apratim Maity, Ethan D L Brown, Max Ward, Emily A Orsino, Daniel M Schneider, Daniel M Sciubba, Sheng-Fu Larry Lo

Purpose: This study aimed to analyze adverse events associated with Mazor X surgical guidance robots, focusing on parameters such as root causes, vertebral distribution, surgical delay, robot abandonment, and more.

Methods: 330 adverse events reported within the Manufacturer and User Facility Device Experience (MAUDE) database for the Mazor X (MX) and Mazor X Stealth Edition (MXSE) robot guidance systems were analyzed and categorized based on the root causes, vertebral distribution, surgical delay, robot abandonment, and patient outcomes.

Results: Both the MX and MXSE adverse events were primarily due to external root causes (35% and 52%, respectively), with user error being the most common. Deviations were most likely to affect the L3, L4, and L5 vertebra, and deviate either medially or laterally. Motor deficits were the most common adverse patient outcome for MX, while sensory deficits were the most common for MXSE. There were two deaths associated with the MX, compared to zero deaths with the MXSE.

Conclusion: While the MAUDE database cannot be used to calculate the incidence or prevalence of adverse events, it provides insight into the types of adverse events that tend to occur with medical devices. MAUDE reports suggest that user-related errors account for most of the adverse events that occur, underscoring the need for focused surgeon training. Our study highlights the importance of understanding both the types of adverse events and their root causes to promote patient safety and reduce complication rates.

目的:本研究旨在分析与Mazor X手术引导机器人相关的不良事件,重点关注诸如根本原因、椎体分布、手术延迟、机器人遗弃等参数。方法:对Mazor X (MX)和Mazor X Stealth Edition (MXSE)机器人引导系统的制造商和用户设施设备体验(MAUDE)数据库中报告的330起不良事件进行分析,并根据根本原因、椎体分布、手术延误、机器人放弃和患者结果进行分类。结果:MX和MXSE不良事件主要是由外部根本原因引起的(分别为35%和52%),用户错误是最常见的。偏移最可能影响L3、L4和L5椎体,并向内侧或外侧偏移。运动缺陷是MX最常见的不良患者结果,而感觉缺陷是MXSE最常见的。与MX相关的死亡有2例,而与MXSE相关的死亡为0例。结论:虽然MAUDE数据库不能用于计算不良事件的发生率或患病率,但它提供了对医疗器械可能发生的不良事件类型的深入了解。MAUDE报告显示,与用户相关的错误是发生的大部分不良事件的原因,这强调了对外科医生进行重点培训的必要性。我们的研究强调了了解不良事件的类型及其根本原因对促进患者安全和减少并发症发生率的重要性。
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引用次数: 0
Treatment strategies and outcomes in the first reported case of severe "Reverse-Folding" spinal deformity: A 2-year follow-up case report. 首例报道的严重“反向折叠”脊柱畸形的治疗策略和结果:2年随访病例报告。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-22 DOI: 10.1007/s00586-025-09698-9
Jianming Zhang, Chao Li, Beiyu Xu, Yao Zhao, Longtao Qi, Lei Yue, Chunde Li, Yu Wang

Introduction: Severe spinal deformities represent rare and complex conditions requiring highly individualized treatment strategies. Among these, the "reverse-folding human" deformity has never before been reported in the medical literature. This study presents the first documented case of this condition, managed successfully through a multidisciplinary team approach and staged posterior spinal instrumentation and fusion. It also establishes the first framework for risk stratification and perioperative management of such extreme deformities.

Methods: Case report.

Case presentation: A 36-year-old woman presented with progressive cervical hyperextension over 26 years and thoracolumbar deformity over 17 years. Clinical and radiological evaluation revealed severe cervical hyperextension, spinal lordosis (Cobb angle: 140.1°), scoliosis (Cobb angle: 87.6°), and severe restrictive pulmonary impairment. The patient underwent a two-stage posterior spinal fusion (C2-S1). Postoperative outcomes included substantial improvement in alignment and gait, with no neurological or mechanical complications over two years of follow-up.

Conclusion: This case demonstrates the feasibility and efficacy of a staged full-spine surgical approach in managing unprecedented spinal deformities. The successful outcome highlights key elements for similar cases: patient-specific surgical planning, staged correction to reduce risks, and coordinated MDT involvement. This report provides a critical clinical reference and treatment framework for managing rare and severe spinal deformities, including the newly defined "reverse-folding human" condition.

简介:严重的脊柱畸形是罕见和复杂的情况,需要高度个性化的治疗策略。其中,“反折叠人”畸形在医学文献中从未报道过。本研究提出了第一例记录在案的这种情况,通过多学科团队的方法和分期后路脊柱内固定和融合术成功治疗。它还建立了这种极端畸形的风险分层和围手术期管理的第一个框架。方法:病例报告。病例介绍:一名36岁女性,表现为26年进行性颈椎过伸和17年胸腰椎畸形。临床和放射学评估显示严重的颈椎过伸、脊柱前凸(Cobb角:140.1°)、脊柱侧凸(Cobb角:87.6°)和严重的限制性肺损伤。患者接受了两期后路脊柱融合术(C2-S1)。术后结果包括对齐和步态的显著改善,在两年的随访中没有出现神经或机械并发症。结论:本病例证明了分阶段全脊柱手术入路治疗前所未有的脊柱畸形的可行性和有效性。成功的结果突出了类似病例的关键因素:针对患者的手术计划,分阶段纠正以降低风险,以及协调MDT介入。本报告为管理罕见和严重的脊柱畸形提供了重要的临床参考和治疗框架,包括新定义的“反向折叠人”状况。
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引用次数: 0
Old technique, new applications: can the H-reflex be a possible real-time indicator in endoscopic surgery for decompression of acute disc herniation at the S1 root? 旧技术,新应用:h反射能否成为内镜手术治疗急性S1根椎间盘突出减压的实时指标?
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-19 DOI: 10.1007/s00586-025-09634-x
Marta Rodrigues Carvalho, Vitor Caldas Marques, Baldomero Pinto Soares, Gabriel Pokorny, Thiego Pedro, Mario Bringel, Rodrigo Grion

Background: The Hoffmann (H-) reflex is a monosynaptic electrophysiological response that reflects S1-root integrity. Although widely used in experimental and in clinical outpatient neurophysiological testing, its intra-operative application during endoscopic lumbar surgery is rarely reported. We present the first real-time documentation of H-reflex normalization immediately after endoscopic decompression of an acute L5-S1 disc herniation.

Case description: A 49-year-old woman presented with acute right-sided S1 radiculopathy (ankle dorsiflexion/plantar-flexion MRC grade III; hallux extension grade I). MRI showed a large, right sub-articular L5-S1 disc extrusion compressing the S1 nerve root. Unilateral biportal endoscopic discectomy was performed under general anesthesia with multimodal intra-operative neuromonitoring (MEPs, free-run EMG, and continuous tibial-nerve H-reflex). Baseline recordings revealed marked side-to-side asymmetry: right-leg MEP amplitudes were depressed, and the right H-reflex was low and unstable. During foraminoplasty and fragment removal, a sudden, sustained 100% surge in right H-reflex amplitude occurred, coincidence with root decompression, while MEPs remained unchanged. Free-run EMG discharges abated after the H-reflex improved. Post-operative recovery was uneventful. At 2 months the patient demonstrated near-complete motor recovery (MRC IV-V) and full pain relief.

Conclusion: Continuous H-reflex monitoring provided an immediate, sensitive marker of S1-root decompression when conventional MEPs failed to reflect functional recovery. This single-case experience supports the feasibility and potential prognostic value of adding H-reflex surveillance to the neuromonitoring toolkit for endoscopic lumbar surgery. Prospective studies in larger cohorts are warranted to validate threshold criteria, refine stimulation parameters, and determine cost-effectiveness.

背景:Hoffmann (H-)反射是一种反映s1根完整性的单突触电生理反应。虽然广泛用于实验和临床门诊神经生理检测,但其在腰椎内镜手术中的术中应用却很少报道。我们提出了急性L5-S1椎间盘突出症内镜减压后立即h反射正常化的第一个实时记录。病例描述:一名49岁女性,表现为急性右侧S1神经根病(踝关节背屈/跖屈MRC III级;拇伸I级)。MRI显示右侧大的关节下L5-S1椎间盘挤压S1神经根。全麻下行单侧双门静脉内窥镜椎间盘切除术,术中多模式神经监测(mep、自由行肌电图和连续胫骨神经h反射)。基线记录显示明显的左右不对称:右腿MEP振幅下降,右侧h反射低且不稳定。在椎间孔成形术和碎片去除过程中,右h反射振幅突然持续100%激增,与根减压一致,而MEPs保持不变。h反射改善后自由运动肌电图放电减弱。术后恢复顺利。2个月时,患者表现出接近完全的运动恢复(MRC IV-V)和完全疼痛缓解。结论:当常规mep不能反映功能恢复时,连续h反射监测提供了快速、敏感的s1根减压标志。这一单一病例的经验支持了在腰椎内窥镜手术的神经监测工具包中增加h反射监测的可行性和潜在的预后价值。在更大的队列中进行前瞻性研究是有必要的,以验证阈值标准,完善刺激参数,并确定成本效益。
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引用次数: 0
Correction: The higher cellular elastic modulus of the nucleus pulposus with degenerative changes in the cervical intervertebral discs. 矫正:髓核较高的细胞弹性模量伴颈椎间盘退行性改变。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-19 DOI: 10.1007/s00586-025-09604-3
Bowei Xiao, Tianchi Zhou, Juying Huang, Tianhua Rong, Bingxuan Wu, Baoge Liu
{"title":"Correction: The higher cellular elastic modulus of the nucleus pulposus with degenerative changes in the cervical intervertebral discs.","authors":"Bowei Xiao, Tianchi Zhou, Juying Huang, Tianhua Rong, Bingxuan Wu, Baoge Liu","doi":"10.1007/s00586-025-09604-3","DOIUrl":"https://doi.org/10.1007/s00586-025-09604-3","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of risk factors for deep vein thrombosis after lumbar endoscopic single-segment decompression without fusion. 腰椎内镜单节段无融合减压术后深静脉血栓形成危险因素分析。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-18 DOI: 10.1007/s00586-025-09591-5
Zhiqiang Wang, Jianguo Zhang, Yongzhuang Ma, Liming He, Yue Wang, Haoyu Feng, Lin Sun
{"title":"Analysis of risk factors for deep vein thrombosis after lumbar endoscopic single-segment decompression without fusion.","authors":"Zhiqiang Wang, Jianguo Zhang, Yongzhuang Ma, Liming He, Yue Wang, Haoyu Feng, Lin Sun","doi":"10.1007/s00586-025-09591-5","DOIUrl":"https://doi.org/10.1007/s00586-025-09591-5","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metagenomic next-generation sequencing for the diagnosis of suspected spinal infections from biopsy samples: a novel biopsy toolkit design and real-life diagnostic value. 从活检样本中诊断疑似脊柱感染的新一代宏基因组测序:一种新的活检工具包设计和现实生活中的诊断价值。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-18 DOI: 10.1007/s00586-025-09686-z
Zhuoyue Li, Shangjie Yang, Chaoran Li, Lin Zhang, Na Xi, Dawei Li, Litao Li
{"title":"Metagenomic next-generation sequencing for the diagnosis of suspected spinal infections from biopsy samples: a novel biopsy toolkit design and real-life diagnostic value.","authors":"Zhuoyue Li, Shangjie Yang, Chaoran Li, Lin Zhang, Na Xi, Dawei Li, Litao Li","doi":"10.1007/s00586-025-09686-z","DOIUrl":"https://doi.org/10.1007/s00586-025-09686-z","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Announcements. 公告。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-18 DOI: 10.1007/s00586-025-09658-3
{"title":"Announcements.","authors":"","doi":"10.1007/s00586-025-09658-3","DOIUrl":"https://doi.org/10.1007/s00586-025-09658-3","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor concerning "Mortality for pneumonia and risk of pneumonia in children with cerebral palsy treated with and without surgery" by Ahonen, et al. (Eur Spine J [2025]; doi: 10.1007/s00586-025-09625-y). Ahonen等人关于“脑瘫患儿肺炎死亡率和肺炎风险”的致编辑信(Eur Spine J [2025]; doi: 10.1007/s00586-025-09625-y)。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2025-12-18 DOI: 10.1007/s00586-025-09694-z
Changzhu Lu, Long Zheng
{"title":"Letter to the Editor concerning \"Mortality for pneumonia and risk of pneumonia in children with cerebral palsy treated with and without surgery\" by Ahonen, et al. (Eur Spine J [2025]; doi: 10.1007/s00586-025-09625-y).","authors":"Changzhu Lu, Long Zheng","doi":"10.1007/s00586-025-09694-z","DOIUrl":"https://doi.org/10.1007/s00586-025-09694-z","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
European Spine Journal
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