Pub Date : 2024-06-02DOI: 10.9734/ijtdh/2024/v45i61552
Suman Kumar, V. Munda, Neha Sharad, Rajan Kumar, Maneesh Kumar, Ratnesh Kumar, M. Jha, Shashank Nand Tiwari, Pratima Gupta
Microbial keratitis is a serious disease of the cornea that poses a major risk to the health and vision of people all over the world. It is caused by various microbial invaders, including bacteria, fungi and viruses, making it difficult to diagnose and treat. Combating microbial keratitis requires understanding the intricate web of immune responses and pathogenic pathways that cause the infection. To develop innovative strategies to treat the disease and improve patient survival, we need to understand how the immune system works, how hosts and infections interact and how complicated the pathophysiology is. Looking to the future, we are on the cusp of a transformative era in treating microbial keratitis. Innovations in therapeutic technology, such as targeted antimicrobial drugs, immunomodulatory therapies and precision medicine techniques, are set to revolutionise the field. These advancements will enable customised treatments for specific microbiological causes and patient characteristics. Integrating molecular biology, imaging and artificial intelligence into novel diagnostic techniques will enhance early diagnosis and personalised treatment programmes, leading to better clinical outcomes and reduced ocular morbidity. Collaboration between clinicians, researchers, and industry representatives is critical to accelerating the translation of scientific knowledge into clinical practice. Improving patient care, increasing treatment efficacy and saving eyesight are the goals for the future of microbial keratitis treatment.
{"title":"Understanding Host-Pathogen Interaction in the Cornea: Inflammatory Response and Cure","authors":"Suman Kumar, V. Munda, Neha Sharad, Rajan Kumar, Maneesh Kumar, Ratnesh Kumar, M. Jha, Shashank Nand Tiwari, Pratima Gupta","doi":"10.9734/ijtdh/2024/v45i61552","DOIUrl":"https://doi.org/10.9734/ijtdh/2024/v45i61552","url":null,"abstract":"Microbial keratitis is a serious disease of the cornea that poses a major risk to the health and vision of people all over the world. It is caused by various microbial invaders, including bacteria, fungi and viruses, making it difficult to diagnose and treat. Combating microbial keratitis requires understanding the intricate web of immune responses and pathogenic pathways that cause the infection. To develop innovative strategies to treat the disease and improve patient survival, we need to understand how the immune system works, how hosts and infections interact and how complicated the pathophysiology is. Looking to the future, we are on the cusp of a transformative era in treating microbial keratitis. Innovations in therapeutic technology, such as targeted antimicrobial drugs, immunomodulatory therapies and precision medicine techniques, are set to revolutionise the field. These advancements will enable customised treatments for specific microbiological causes and patient characteristics. Integrating molecular biology, imaging and artificial intelligence into novel diagnostic techniques will enhance early diagnosis and personalised treatment programmes, leading to better clinical outcomes and reduced ocular morbidity. Collaboration between clinicians, researchers, and industry representatives is critical to accelerating the translation of scientific knowledge into clinical practice. Improving patient care, increasing treatment efficacy and saving eyesight are the goals for the future of microbial keratitis treatment.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE & Health","volume":"6 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141273535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-21DOI: 10.9734/ijtdh/2024/v45i61550
Abebe E. Stephen, Obaseki I. Flourish, Dongo E. Naomi, Idialu. O. Perpetual, Uhomoibhi O. David, Omokaro J. Endurance, Ehizuelen G. Ehis, Osejele I. Meshach, Uangbaoje A. Cyril, Ugwoke O. Albert, Okpu U. Jeremiah, Ighodaro T. Osazuwa, Ogedegbe S. Idemudia, Jerhovwen Joshua, Okolo C. Caleb, Akhaine J. Precious
Introduction: Vaccine hesitancy is a major challenge to public health, particularly in the context of the COVID-19 pandemic. This research was aimed at examining COVID-19 vaccine hesitancy in the Idumebo Community, Irrua, Edo State, Nigeria, to understand the factors influencing vaccine acceptance and refusal. Objective: The primary objective of this research was to determine the level of knowledge, uptake, and reasons for vaccine hesitancy among residents of Idumebo, Irrua Edo State. By exploring these factors, the study aimed to provide insights that can inform targeted interventions to improve vaccine acceptance rates in the community. Method: A descriptive cross-sectional study was done among residents of age 18-60 years in Idumebo, utilizing structured questionnaires to gather data on socio-demographic characteristics, knowledge of COVID-19, and attitudes towards vaccination. Ethical considerations were prioritized, with institutional and community consent obtained before data collection. Results: The findings showed a high degree of awareness of COVID-19 among participants, with a majority acknowledging the contagious nature of the disease. However, vaccine hesitancy was observed among a subset of respondents, with reasons ranging from concerns about safety and efficacy to misinformation and mistrust. These results underscore the need for targeted educational campaigns and community engagement to address vaccine hesitancy effectively. Conclusion: It was concluded that the study brought to light the complex dynamics of COVID-19 vaccine hesitancy in the Idumebo Community, revealing the necessity of tailored interventions to address barriers to vaccine acceptance. By fostering a better understanding of community attitudes and concerns, public health authorities can develop strategies to enhance vaccine uptake and combat the spread of COVID-19 in the region.
{"title":"COVID-19 Vaccine Hesitancy in a Rural Community of Nigeria","authors":"Abebe E. Stephen, Obaseki I. Flourish, Dongo E. Naomi, Idialu. O. Perpetual, Uhomoibhi O. David, Omokaro J. Endurance, Ehizuelen G. Ehis, Osejele I. Meshach, Uangbaoje A. Cyril, Ugwoke O. Albert, Okpu U. Jeremiah, Ighodaro T. Osazuwa, Ogedegbe S. Idemudia, Jerhovwen Joshua, Okolo C. Caleb, Akhaine J. Precious","doi":"10.9734/ijtdh/2024/v45i61550","DOIUrl":"https://doi.org/10.9734/ijtdh/2024/v45i61550","url":null,"abstract":"Introduction: Vaccine hesitancy is a major challenge to public health, particularly in the context of the COVID-19 pandemic. This research was aimed at examining COVID-19 vaccine hesitancy in the Idumebo Community, Irrua, Edo State, Nigeria, to understand the factors influencing vaccine acceptance and refusal. \u0000Objective: The primary objective of this research was to determine the level of knowledge, uptake, and reasons for vaccine hesitancy among residents of Idumebo, Irrua Edo State. By exploring these factors, the study aimed to provide insights that can inform targeted interventions to improve vaccine acceptance rates in the community. \u0000Method: A descriptive cross-sectional study was done among residents of age 18-60 years in Idumebo, utilizing structured questionnaires to gather data on socio-demographic characteristics, knowledge of COVID-19, and attitudes towards vaccination. Ethical considerations were prioritized, with institutional and community consent obtained before data collection. \u0000Results: The findings showed a high degree of awareness of COVID-19 among participants, with a majority acknowledging the contagious nature of the disease. However, vaccine hesitancy was observed among a subset of respondents, with reasons ranging from concerns about safety and efficacy to misinformation and mistrust. These results underscore the need for targeted educational campaigns and community engagement to address vaccine hesitancy effectively. \u0000Conclusion: It was concluded that the study brought to light the complex dynamics of COVID-19 vaccine hesitancy in the Idumebo Community, revealing the necessity of tailored interventions to address barriers to vaccine acceptance. By fostering a better understanding of community attitudes and concerns, public health authorities can develop strategies to enhance vaccine uptake and combat the spread of COVID-19 in the region.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE & Health","volume":"55 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141116573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-23DOI: 10.9734/ijtdh/2024/v45i61543
T. Kuete, Henri Essome, Larissa Boukam Moche, Nadège Anabianina, Christiane Keddy Mangamba, A. Ekobo
Pregnancy malaria is a life-threatening condition to the mother, the fetus and the newborn. Since the implementation of the World Health Organization’s recommendations of specific malaria control strategies to pregnant women in malaria endemic countries, evaluation studies are needed to assess the prevalence of malaria in pregnancy. This cross-sectional prospective study was therefore set to determine the prevalence and associated factors as well as the treatment outcomes of Plasmodium infection among pregnant women attending antenatal care in three hospitals of Douala in Cameroon. Each volunteered pregnant woman received for antenatal care was questioned according to the study questionnaire to collect sociodemographic data, use of malaria prevention tools and pregnancy history. Then a laboratory test was carried for Plasmodium detection in the peripheral blood using microscopy and a HRP2-based rapid diagnostic test. Plasmodium carrying pregnant women were treated according to the national malaria program scheme followed by post-treatment follow-up. Data were processed and analyzed using SPSS.20 software. Association of Plasmodium infection with risk factors was analyzed as univariate using Pearson Chi-square and Fisher Exact tests considering a P-value < 0.05 as statistically significant. A total of 487 pregnant women aged between 18 years and 42 years were included in the study. The prevalence of Plasmodium infection was 3.5% and 4.3% by malaria rapid diagnostic test and microscopy respectively. Only Plasmodium falciparum asexual stage was detected. Parasite loads were low. Factors associated with Plasmodium falciparum higher prevalence were being less than 21 years old (0.02), not sleeping under mosquitoe net daily (p=0.04) and having fever during the pregnancy (p=0.04). Parenteral treatment with either artesunate, artemether or quinine sulfate showed good efficacy. Conclusion: Pregnant women attending the antenatal cares harbored low Plasmodium infection prevalence and loads. Being of young age, not sleeping under mosquitoe bednet daily and having fever during the pregnancy were predictive Plasmodium falciparum. Plasmodium infected pregnant women were successfully treated with antimalarial medications recommended by the national Ministry of Public Health. The authors recommend increasing efforts by health authorities to strengthen malaria prevention in pregnant women through more adherence to sleeping under ITNs daily and taking IPT-sp as well as systematic detection of Plasmodium infection at each antenatal visit.
{"title":"Prevalence, Associated Factors and Treatment Outcomes of Laboratory-confirmed Pregnancy Malaria at Antenatal Care in Three Healthcare Facilities of Douala, Cameroon","authors":"T. Kuete, Henri Essome, Larissa Boukam Moche, Nadège Anabianina, Christiane Keddy Mangamba, A. Ekobo","doi":"10.9734/ijtdh/2024/v45i61543","DOIUrl":"https://doi.org/10.9734/ijtdh/2024/v45i61543","url":null,"abstract":"Pregnancy malaria is a life-threatening condition to the mother, the fetus and the newborn. Since the implementation of the World Health Organization’s recommendations of specific malaria control strategies to pregnant women in malaria endemic countries, evaluation studies are needed to assess the prevalence of malaria in pregnancy. This cross-sectional prospective study was therefore set to determine the prevalence and associated factors as well as the treatment outcomes of Plasmodium infection among pregnant women attending antenatal care in three hospitals of Douala in Cameroon. \u0000Each volunteered pregnant woman received for antenatal care was questioned according to the study questionnaire to collect sociodemographic data, use of malaria prevention tools and pregnancy history. Then a laboratory test was carried for Plasmodium detection in the peripheral blood using microscopy and a HRP2-based rapid diagnostic test. Plasmodium carrying pregnant women were treated according to the national malaria program scheme followed by post-treatment follow-up. Data were processed and analyzed using SPSS.20 software. Association of Plasmodium infection with risk factors was analyzed as univariate using Pearson Chi-square and Fisher Exact tests considering a P-value < 0.05 as statistically significant. \u0000A total of 487 pregnant women aged between 18 years and 42 years were included in the study. The prevalence of Plasmodium infection was 3.5% and 4.3% by malaria rapid diagnostic test and microscopy respectively. Only Plasmodium falciparum asexual stage was detected. Parasite loads were low. Factors associated with Plasmodium falciparum higher prevalence were being less than 21 years old (0.02), not sleeping under mosquitoe net daily (p=0.04) and having fever during the pregnancy (p=0.04). Parenteral treatment with either artesunate, artemether or quinine sulfate showed good efficacy. \u0000Conclusion: Pregnant women attending the antenatal cares harbored low Plasmodium infection prevalence and loads. Being of young age, not sleeping under mosquitoe bednet daily and having fever during the pregnancy were predictive Plasmodium falciparum. Plasmodium infected pregnant women were successfully treated with antimalarial medications recommended by the national Ministry of Public Health. The authors recommend increasing efforts by health authorities to strengthen malaria prevention in pregnant women through more adherence to sleeping under ITNs daily and taking IPT-sp as well as systematic detection of Plasmodium infection at each antenatal visit.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE & Health","volume":"26 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140672252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-17DOI: 10.9734/ijtdh/2024/v45i61542
Nnenna Victoria Ezugwu, Alicia Gayle, Chris Anyamene
Aim: To assess the impact of WASH services in mitigating the proliferation of AMR in Nigeria, with the United Kingdom serving as a reference population. Study Design: This is a review article. Duration of Study: An extensive review was conducted in relevant databases, specifically focusing on research studies published in peer-reviewed journals in English. These studies were conducted in both the United Kingdom and Nigeria, with the primary objective of investigating the relationship between Water, Sanitation, and Hygiene practices and Antimicrobial Resistance. The search spanned from May 2015, coinciding with the adoption of the global action on antimicrobial resistance by the World Health Assembly, to July 2023. The literature search was completed on August 10, 2023. Methodology: The search involved electronic databases such as EBSCO, PubMed, Science Direct, and CINAHL Complete. Additionally, relevant literature was searched on the websites of organizations such as the World Health Organization, Nigeria Centre for Disease Control and Prevention, and the Centre for Disease Control and Prevention, Public Health England. The quality of the papers was evaluated using CASP tools to determine their reproducibility, credibility, dependability, and confirmability. Out of the initial 705 articles that were drawn from the different databases, 12 studies were included in the literature review. Results: The review of the various literature showed that WASH interventions in Nigeria are geared toward disease transmission/infection prevention and control and not the combatting of AMR while studies in the UK have shown positive advances in tackling AMR utilizing WASH services. Conclusion: Promoting the development and provision of WASH infrastructure in diverse Nigerian settings is crucial for addressing antimicrobial resistance (AMR). This literature review serves as a call to action for stakeholders at the national, regional, and local levels in Nigeria, emphasizing the necessity of nationwide investment in WASH infrastructure, the development of policies that support the implementation of WASH in all the communities and villages, extensive health promotion campaigns to raise awareness about AMR, and community-level interventions to contain the spread of AMR in Nigeria.
{"title":"Epidemiology of Antimicrobial Resistance and the Wash Project: Averting a Potential Public Health Crisis in Nigeria Using the United Kingdom as a Case Study","authors":"Nnenna Victoria Ezugwu, Alicia Gayle, Chris Anyamene","doi":"10.9734/ijtdh/2024/v45i61542","DOIUrl":"https://doi.org/10.9734/ijtdh/2024/v45i61542","url":null,"abstract":"Aim: To assess the impact of WASH services in mitigating the proliferation of AMR in Nigeria, with the United Kingdom serving as a reference population.\u0000Study Design: This is a review article.\u0000Duration of Study: An extensive review was conducted in relevant databases, specifically focusing on research studies published in peer-reviewed journals in English. These studies were conducted in both the United Kingdom and Nigeria, with the primary objective of investigating the relationship between Water, Sanitation, and Hygiene practices and Antimicrobial Resistance. The search spanned from May 2015, coinciding with the adoption of the global action on antimicrobial resistance by the World Health Assembly, to July 2023. The literature search was completed on August 10, 2023.\u0000Methodology: The search involved electronic databases such as EBSCO, PubMed, Science Direct, and CINAHL Complete. Additionally, relevant literature was searched on the websites of organizations such as the World Health Organization, Nigeria Centre for Disease Control and Prevention, and the Centre for Disease Control and Prevention, Public Health England. The quality of the papers was evaluated using CASP tools to determine their reproducibility, credibility, dependability, and confirmability. Out of the initial 705 articles that were drawn from the different databases, 12 studies were included in the literature review.\u0000Results: The review of the various literature showed that WASH interventions in Nigeria are geared toward disease transmission/infection prevention and control and not the combatting of AMR while studies in the UK have shown positive advances in tackling AMR utilizing WASH services.\u0000Conclusion: Promoting the development and provision of WASH infrastructure in diverse Nigerian settings is crucial for addressing antimicrobial resistance (AMR). This literature review serves as a call to action for stakeholders at the national, regional, and local levels in Nigeria, emphasizing the necessity of nationwide investment in WASH infrastructure, the development of policies that support the implementation of WASH in all the communities and villages, extensive health promotion campaigns to raise awareness about AMR, and community-level interventions to contain the spread of AMR in Nigeria.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE & Health","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140692130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-15DOI: 10.9734/ijtdh/2024/v45i61540
Bombey Mary-Flavie Nkanjo, Tendongfor Nicholas, E. Ojong
Introduction: Malnutrition refers to deficiencies, excesses, or imbalances in a person’s intake of energy and/or nutrients and HIV which infects CD4 cells causes immune suppression which can further be worsened by poor nutrition. More than 37.7 million people are living with HIV in the world out of which about 36 million are adults. Aims: The study aimed to determine the prevalence of malnutrition and associated factors among human immunodeficiency virus (HIV) seropositive adults on antiretroviral therapy at the HIV care and treatment center of the Buea Regional hospital, Cameroon. Study Design: A Hospital-based Cross sectional study design. Place and duration of study: Buea regional hospital at the HIV care and treatment centre, South West Region of Cameroon between April 2022 to June 2022. Materials and method: We included 139 HIV seropositive individuals (17 men, 177 women age range 26 to 59 years). Nutritional status was assessed using anthropometric and clinical methods. A 24-hour dietary diversity was assessed using a questionnaire. Data was analyzed using SPSS version 25.0. Results: The prevalence of underweight, overweight and obesity among the participants were 1.4 %, 38.8%, and 24.4% respectively. In the bivariate analysis, sex of the participants (χ2 = 4.715, p = 0.030) and attendance to HIV-related counseling sessions (χ2 = 4.512, p = 0.034) were significantly associated with malnutrition. The mean dietary diversity score of the study respondents was 4.97±1.6 with only 37% of the respondents achieving a minimum dietary diversity. In the multivariate logistic regression analysis, the odds of those who received HIV-related counselling being malnourished(overweight) was 3.29 times more than those who did not receive HIV-related counselling (AOR=3.29, p=0.036). Conclusions: There is a high burden of overweight and obesity in the HIV population of the Regional Hospital Buea. The only factor independently associated to malnutrition(overweight) was uptake of nutrition related counselling. Majority of the HIV seropositive patients in the Regional Hospital Buea had a poor dietary diversity. Nutritional counseling should be an important part of persons living with HIV/AIDS (PLWHA) routine follow-up.
{"title":"Prevalence of Malnutrition and Associated Factors among HIV Seropositive Adults on Antiretroviral Therapy at the Regional Hospital, Buea, Cameroon","authors":"Bombey Mary-Flavie Nkanjo, Tendongfor Nicholas, E. Ojong","doi":"10.9734/ijtdh/2024/v45i61540","DOIUrl":"https://doi.org/10.9734/ijtdh/2024/v45i61540","url":null,"abstract":"Introduction: Malnutrition refers to deficiencies, excesses, or imbalances in a person’s intake of energy and/or nutrients and HIV which infects CD4 cells causes immune suppression which can further be worsened by poor nutrition. More than 37.7 million people are living with HIV in the world out of which about 36 million are adults.\u0000Aims: The study aimed to determine the prevalence of malnutrition and associated factors among human immunodeficiency virus (HIV) seropositive adults on antiretroviral therapy at the HIV care and treatment center of the Buea Regional hospital, Cameroon.\u0000Study Design: A Hospital-based Cross sectional study design.\u0000Place and duration of study: Buea regional hospital at the HIV care and treatment centre, South West Region of Cameroon between April 2022 to June 2022.\u0000Materials and method: We included 139 HIV seropositive individuals (17 men, 177 women age range 26 to 59 years). Nutritional status was assessed using anthropometric and clinical methods. A 24-hour dietary diversity was assessed using a questionnaire. Data was analyzed using SPSS version 25.0.\u0000Results: The prevalence of underweight, overweight and obesity among the participants were 1.4 %, 38.8%, and 24.4% respectively. In the bivariate analysis, sex of the participants (χ2 = 4.715, p = 0.030) and attendance to HIV-related counseling sessions (χ2 = 4.512, p = 0.034) were significantly associated with malnutrition. The mean dietary diversity score of the study respondents was 4.97±1.6 with only 37% of the respondents achieving a minimum dietary diversity. In the multivariate logistic regression analysis, the odds of those who received HIV-related counselling being malnourished(overweight) was 3.29 times more than those who did not receive HIV-related counselling (AOR=3.29, p=0.036). \u0000Conclusions: There is a high burden of overweight and obesity in the HIV population of the Regional Hospital Buea. The only factor independently associated to malnutrition(overweight) was uptake of nutrition related counselling. Majority of the HIV seropositive patients in the Regional Hospital Buea had a poor dietary diversity. Nutritional counseling should be an important part of persons living with HIV/AIDS (PLWHA) routine follow-up.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE & Health","volume":"33 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140699430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-15DOI: 10.9734/ijtdh/2024/v45i61541
O. Ekwebene, Ijeoma Chukwu Amaechi, Ipinoluwa Akintola, Ezera Emetu
The “Type of Article” of this paper is “Letter to the Editor”. This paper discuses about: “Analyzing the Flint Water Crisis: Insights and Suggestions for Future Resilience”. No formal abstract is available. Readers are requested to read the full article.
{"title":"Analyzing the Flint Water Crisis: Insights and Suggestions for Future Resilience","authors":"O. Ekwebene, Ijeoma Chukwu Amaechi, Ipinoluwa Akintola, Ezera Emetu","doi":"10.9734/ijtdh/2024/v45i61541","DOIUrl":"https://doi.org/10.9734/ijtdh/2024/v45i61541","url":null,"abstract":"The “Type of Article” of this paper is “Letter to the Editor”. This paper discuses about: “Analyzing the Flint Water Crisis: Insights and Suggestions for Future Resilience”. No formal abstract is available. Readers are requested to read the full article.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE & Health","volume":"5 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140700977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-11DOI: 10.9734/ijtdh/2024/v45i61538
L. K. Sigey
Aim: The aim of this study was to explore factors that influence intentional self-poisoning among patients aged 15-30 years in Kericho County. The study's specific goals were to explore the influence of family factors, on intentional self-organophosphate poisoning. Study Design: The study adopted cross-sectional study design. Place and Duration of Study: Study was conducted in Kericho County, health facilities for a period of 4 months. Methodology: 100 respondents were included in the study (88 males and 12 females). Sample size of 100 respondents was used which was estimated population of patients who might have been affected with poisoning during study period. Data was collected from respondents who were attended and recovered during the study period of four months. Data Analysis: The collected quantitative data was analyzed using Statistical Package for Social Sciences (SPSS) version 21. Correlation and regression analysis were carried out to establish relationship between categorical variables. The analyzed data were presented in tables, charts and the corresponding thematic areas. Statistical significance was set at p<0.05. Result: The results indicated that family factors showed positive influenced on self-poisoning. had correlation of 13.319 where significance was set at p=0.0001 indicating a high likelihood of influencing one to self-poison. Conclusion: This study suggested counselors to have a prediction model to classify patients at a higher risk of self-harm by use of poisons and to focus on individual preventive strategies. Patients in the high-risk group require referral for mental health assessment and counseling both individual and family to alleviate helplessness and hopelessness, healthy lifestyle like come together party, and restriction of access to poison .This will eventually reduce these cases of self-poisoning in our Counties and Country at large.
{"title":"Family Factors Influencing Intentional Self-organophosphate Poisoning Among Persons of Age 15-30 Years in Kericho County, Kenya","authors":"L. K. Sigey","doi":"10.9734/ijtdh/2024/v45i61538","DOIUrl":"https://doi.org/10.9734/ijtdh/2024/v45i61538","url":null,"abstract":"Aim: The aim of this study was to explore factors that influence intentional self-poisoning among patients aged 15-30 years in Kericho County. The study's specific goals were to explore the influence of family factors, on intentional self-organophosphate poisoning.\u0000Study Design: The study adopted cross-sectional study design.\u0000Place and Duration of Study: Study was conducted in Kericho County, health facilities for a period of 4 months.\u0000Methodology: 100 respondents were included in the study (88 males and 12 females).\u0000Sample size of 100 respondents was used which was estimated population of patients who might have been affected with poisoning during study period. Data was collected from respondents who were attended and recovered during the study period of four months.\u0000Data Analysis: The collected quantitative data was analyzed using Statistical Package for Social Sciences (SPSS) version 21. Correlation and regression analysis were carried out to establish relationship between categorical variables. The analyzed data were presented in tables, charts and the corresponding thematic areas. Statistical significance was set at p<0.05.\u0000Result: The results indicated that family factors showed positive influenced on self-poisoning. had correlation of 13.319 where significance was set at p=0.0001 indicating a high likelihood of influencing one to self-poison.\u0000 Conclusion: This study suggested counselors to have a prediction model to classify patients at a higher risk of self-harm by use of poisons and to focus on individual preventive strategies. Patients in the high-risk group require referral for mental health assessment and counseling both individual and family to alleviate helplessness and hopelessness, healthy lifestyle like come together party, and restriction of access to poison .This will eventually reduce these cases of self-poisoning in our Counties and Country at large.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE & Health","volume":"33 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140714221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-11DOI: 10.9734/ijtdh/2024/v45i61539
L. K. Sigey
Background: Suicide has been among the leading causes of death in 15-29-year-old people worldwide. Over three quarters (79%) of all suicides occur in lower and mid-level economic countries. Aim: The study's specific goal was to assess factors influencing personal specific life events on intentional self-organophosphate poisoning. Place and Duration of Study: Study was conducted in Kericho County, health facilities year 2023. Design: The study adopted cross-sectional study design and purposive sampling technique. Methodology: 100 respondents were included in the study(88 males and 12 females). Data Analysis: The collected quantitative data were analyzed using Statistical Package for Social Sciences (SPSS) version 21. Correlation and regression analysis was carried out to establish relationship between variables. Chi-square also was used to measure correlation of variables.The analyzed data were presented in tables, charts and the corresponding thematic areas. Statistical significance was set at p<0.05. Results: The results indicated that personal life specific perspective showed positive influenced on self-poisoning. The results indicated that personal specific perspectives/events had chi-square of 13.867 where significance was set at p=0.0001 indicating a high likelihood of influencing one to self-poison. Conclusion: Self-poisoning study offers important knowledge on one of the commonest popular methods of self- suicidal attempts; that can guide on public health approaches to mitigate this phenomenon, and the lack of research on the influences of personality traits and self-poisoning is the main reason for this study. These cases of self-poisoning influence by self-perfection may increase morbidity and mortality incidences and also overburdening family financially to meet cost of hospitalization.
{"title":"Study of Person-specifc Life Events Influencing Intentional Self-harm in Young Population in Kericho County, Kenya","authors":"L. K. Sigey","doi":"10.9734/ijtdh/2024/v45i61539","DOIUrl":"https://doi.org/10.9734/ijtdh/2024/v45i61539","url":null,"abstract":"Background: Suicide has been among the leading causes of death in 15-29-year-old people worldwide. Over three quarters (79%) of all suicides occur in lower and mid-level economic countries.\u0000Aim: The study's specific goal was to assess factors influencing personal specific life events on intentional self-organophosphate poisoning.\u0000Place and Duration of Study: Study was conducted in Kericho County, health facilities year 2023.\u0000Design: The study adopted cross-sectional study design and purposive sampling technique.\u0000Methodology: 100 respondents were included in the study(88 males and 12 females).\u0000Data Analysis: The collected quantitative data were analyzed using Statistical Package for Social Sciences (SPSS) version 21. Correlation and regression analysis was carried out to establish relationship between variables. Chi-square also was used to measure correlation of variables.The analyzed data were presented in tables, charts and the corresponding thematic areas. Statistical significance was set at p<0.05. \u0000Results: The results indicated that personal life specific perspective showed positive influenced on self-poisoning. The results indicated that personal specific perspectives/events had chi-square of 13.867 where significance was set at p=0.0001 indicating a high likelihood of influencing one to self-poison.\u0000Conclusion: Self-poisoning study offers important knowledge on one of the commonest popular methods of self- suicidal attempts; that can guide on public health approaches to mitigate this phenomenon, and the lack of research on the influences of personality traits and self-poisoning is the main reason for this study. These cases of self-poisoning influence by self-perfection may increase morbidity and mortality incidences and also overburdening family financially to meet cost of hospitalization.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE & Health","volume":"59 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140713591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-09DOI: 10.9734/ijtdh/2024/v45i61537
Nnenna Ihua, Owhorchukwu Amadi-Wali, E. Onosakponome, Chidi L. C. Ndukwu, R. A. Ikpeama, C. U. Okorocha
Water, sanitation and hygiene (WASH) play key roles in management of infectious diseases like cholera and other waterborne diseases; given that millions of people globally have no access to safe water. This cross-sectional study, conducted in 7 communities of Ogoni region (Khana, Gokana, Tai and Eleme LGAs), Orashi region (Abua/Odual, Ahoada West, Ahoada East and Ogba-Egbema-Ndoni LGAs) and Obolo region (Andoni LGA) all in Rivers State, Nigeria, enrolled 274 inhabitants comprising 164 females and 110 males. These included persons passing watery stools accompanied with vomiting, abdominal cramps and those with such prehistory. Questionnaires were used to obtain socio-demographic data. A total of 274 faecal samples were collected and transported in Cary-Blair stool culture transport medium to Rivers State University Teaching Hospital laboratory; and inoculated on Thiosulphate sulphate citrate bile salt-sucrose agar. Gram staining and biochemical tests were performed using standard procedures. Among the 274 subjects, 40 were infected giving a prevalence rate of 14.6%, including 26(15.9%) females and 14(12.7%) males though this was statistically insignificant, (U=8738.000, p=0.474). On educational levels, those who attended secondary schools had the highest prevalence rate (26.3%), compared with others and it was statistically significant, (p=0.00). WASH perceived predisposing factor showed the prevalence rate among those without access to safe water was 33(21.6%) against those with access to safe water 7(5.8%) and was statistically significant, (p=0.00). Subjects engaged in routine environmental sanitation and hygiene practices had lower prevalence 7(7.6%) than their counterparts, 33(18.1%), p=0.02. Respondents who think climate change had a positive impact on cholera transmission had prevalence of 34(23.3%) against those who disagreed, 6(4.7%), which was statistically significant. The study deduced that unavailability of safe drinking water, climate change, and unhygienic practices were major predisposing factors to cholera infection. Provision of safe water is advocated as greater percentage of the communities lacked access to safe drinking water. Routine environmental sanitation exercise should be revisited and enforced.
{"title":"Public Health Implications of Cholera- a Water Sanitation and Hygiene (WASH) Related Infectious Disease in the Era of Climate Change: The Nigeria Experience","authors":"Nnenna Ihua, Owhorchukwu Amadi-Wali, E. Onosakponome, Chidi L. C. Ndukwu, R. A. Ikpeama, C. U. Okorocha","doi":"10.9734/ijtdh/2024/v45i61537","DOIUrl":"https://doi.org/10.9734/ijtdh/2024/v45i61537","url":null,"abstract":"Water, sanitation and hygiene (WASH) play key roles in management of infectious diseases like cholera and other waterborne diseases; given that millions of people globally have no access to safe water. This cross-sectional study, conducted in 7 communities of Ogoni region (Khana, Gokana, Tai and Eleme LGAs), Orashi region (Abua/Odual, Ahoada West, Ahoada East and Ogba-Egbema-Ndoni LGAs) and Obolo region (Andoni LGA) all in Rivers State, Nigeria, enrolled 274 inhabitants comprising 164 females and 110 males. These included persons passing watery stools accompanied with vomiting, abdominal cramps and those with such prehistory. Questionnaires were used to obtain socio-demographic data. A total of 274 faecal samples were collected and transported in Cary-Blair stool culture transport medium to Rivers State University Teaching Hospital laboratory; and inoculated on Thiosulphate sulphate citrate bile salt-sucrose agar. Gram staining and biochemical tests were performed using standard procedures. Among the 274 subjects, 40 were infected giving a prevalence rate of 14.6%, including 26(15.9%) females and 14(12.7%) males though this was statistically insignificant, (U=8738.000, p=0.474). On educational levels, those who attended secondary schools had the highest prevalence rate (26.3%), compared with others and it was statistically significant, (p=0.00). WASH perceived predisposing factor showed the prevalence rate among those without access to safe water was 33(21.6%) against those with access to safe water 7(5.8%) and was statistically significant, (p=0.00). Subjects engaged in routine environmental sanitation and hygiene practices had lower prevalence 7(7.6%) than their counterparts, 33(18.1%), p=0.02. Respondents who think climate change had a positive impact on cholera transmission had prevalence of 34(23.3%) against those who disagreed, 6(4.7%), which was statistically significant. The study deduced that unavailability of safe drinking water, climate change, and unhygienic practices were major predisposing factors to cholera infection. Provision of safe water is advocated as greater percentage of the communities lacked access to safe drinking water. Routine environmental sanitation exercise should be revisited and enforced.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE & Health","volume":"67 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140721825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Many causes, including the efficiency of plant medicines and their lower side effects when compared to contemporary medications, have contributed to the current rebirth of plant therapies. Given the current situation, basic scientific research on the therapeutic herbs utilized in indigenous systems is urgently needed. The purpose of this review is to provide information on current developments in the study of medicinal plants recognized for their antiurolithiatic properties. This could assist researchers in determining and creating suitable lead compounds or plant products that are advantageous in the treatment of urolithiasis. A series of physicochemical processes, including supersaturation, nucleation, growth, aggregation, and retention inside the kidneys, combine to form kidney stones. In developed nations, 10–12% of people suffer from urinary stones. There are very few places in the world where stone disease is uncommon, such as Germany and the coastal regions of Japan. Thus, the purpose of this review is to provide information about current developments in the study of medicinal plants recognized for their antiurolithiatic properties. Researchers may find this article useful in identifying the primary compounds or herbal products that exhibit urolithiatic activity.
{"title":"Evaluation of Anti-urolithiasis Activity by Nucleation Assay","authors":"Siddhartha Lolla, Harika Peddinti, Sravanthi Gojuvaka, Samrin Saba, Uma Devi Dasari, Madhavi Pillalamarri","doi":"10.9734/ijtdh/2024/v45i61535","DOIUrl":"https://doi.org/10.9734/ijtdh/2024/v45i61535","url":null,"abstract":"Many causes, including the efficiency of plant medicines and their lower side effects when compared to contemporary medications, have contributed to the current rebirth of plant therapies. Given the current situation, basic scientific research on the therapeutic herbs utilized in indigenous systems is urgently needed. The purpose of this review is to provide information on current developments in the study of medicinal plants recognized for their antiurolithiatic properties. This could assist researchers in determining and creating suitable lead compounds or plant products that are advantageous in the treatment of urolithiasis. A series of physicochemical processes, including supersaturation, nucleation, growth, aggregation, and retention inside the kidneys, combine to form kidney stones. In developed nations, 10–12% of people suffer from urinary stones. There are very few places in the world where stone disease is uncommon, such as Germany and the coastal regions of Japan. Thus, the purpose of this review is to provide information about current developments in the study of medicinal plants recognized for their antiurolithiatic properties. Researchers may find this article useful in identifying the primary compounds or herbal products that exhibit urolithiatic activity.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE & Health","volume":"136 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140731348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}