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Update Research of TCM -for – COVID-19 COVID-19中药的最新研究成果
Pub Date : 2023-11-25 DOI: 10.9734/ijtdh/2023/v44i221495
Du Ning, Liu Jing, Furong Zheng, Fuyong Jiao, Shixia Liang
Objective: To explore the role of traditional Chinese medicine in the treatment of COVID-19. Methods: By consulting the relevant literature, to find out the relevant studies of TCM treatment of COVID-19. We refer to the existing domestic articles for analysis and find that TCM plays a crucial role in the treatment of COVID-19. It has been recognized in the world. Many countries took the lead in treating COVID-19, and their novel coronavirus control is more effective than other way-s. Results: Clinical practice has shown that TCM is an important means of treatment for COVID-19. Chinese acupuncture, cupping, massage, and Chinese medicine are all crucial to the treatment of COVID-19, achieving accurate identification, timely diagnosis, symptomatic treatment, and reduction of complications. Conclusion: TCM has better-effects in the from COVID-19 because of its arrangement and regulation effect.
目的探讨中药在治疗 COVID-19 中的作用。方法:通过查阅相关文献,了解中医药治疗 COVID-19 的相关研究:通过查阅相关文献,了解中医药治疗 COVID-19 的相关研究。参考国内现有文章进行分析,发现中医药在 COVID-19 的治疗中起着至关重要的作用。它已被世界所认可。许多国家在治疗COVID-19方面走在了前列,其新型冠状病毒控制方法比其他方法更有效。结果:临床实践表明,中医是治疗 COVID-19 的重要手段。中医针灸、拔罐、推拿、中药等都是治疗 COVID-19 的关键,能做到准确辨证、及时诊断、对症治疗、减少并发症。结论中医药对 COVID-19 有较好的调理作用。
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引用次数: 0
Antityphoid and Antioxidant Activities of Leaf Extracts of Dracaena deisteliana Eng. (Dracaenaceae) 龙脑香(龙脑香科)叶提取物的抗呕吐和抗氧化活性
Pub Date : 2023-11-23 DOI: 10.9734/ijtdh/2023/v44i221494
H. B. L. Feudjio, M. Goka, J. Djenguemtar, G. T. Kamsu, J. B. Sokoudjou, L. N. Famen, N. Kodjio, D. Gatsing
Salmonellosis is a major public health problem in developing countries where it is endemic. The genus Salmonella express the oxyR gene that codes for several proteins that allow them to resist free radicals. To investigate the antioxidant activity in vitro (aqueous and hydroethanolic extracts in vivo (of the 55% hydroethanolic extract)) of Dracaena deisteliana leaves in albino’s rats of Wistar strain previously infected with the Salmonella Typhi ATCC 6539 strain. The in vitro antioxidant activity of these extracts was determined by studying their anti-radical power with DPPH●, then their iron-reducing power and determining their flavonoids and total phenols content. The in vivo antioxidant activity was determined in plasma and tissues of albino’s rats of wistar strain aged between 8 and 10 weeks previously infected with Salmonella typhi ATCC 6539. These infected rats concurrently received daily doses of Dracaena deisteliana extract (10, 20 and 51.84 mg/kg) and ciprofloxacin (14 mg/kg) as positive control, for 15 days. At the end of the treatment period, the animals were sacrificed and blood, liver, kidney, heart, lung, spleen testis and ovaris were collected for evaluation of antioxidants parameters, which included malondialdehyde, nitric oxide, catalase and peroxidase, as well as biological responses. Regarding the in vitro antioxidant tests, the 55% hydroethanolic extract had the best IC50 (11.99 μg/ml). The iron reducing power of this extract was higher than the other extracts at 200 μg/ml. The highest levels of flavonoids and total phenols were obtained respectively with this extract. This extract (10, 20 and 51.84 mg/kg) cured the infected rats between the 8th and 12th day of treatment. The extract also significantly reduced blood malondialdehyde and nitric oxide levels, and significantly increased the activity of catalase and peroxidase in the infected rats. The results suggest that leaves extract of Dracaena deisteliana contains antisalmonella and antioxidant substances, which could be used for the treatment of typhoid fever and reduces the state of oxidative stress caused by Salmonella. Typhi during rat’s infection.
在沙门氏菌病流行的发展中国家,沙门氏菌病是一个主要的公共卫生问题。沙门氏菌属表达氧R基因,该基因编码多种蛋白质,使其能够抵抗自由基。本研究的目的是对之前感染了伤寒沙门氏菌 ATCC 6539 株的 Wistar 型白化大鼠进行龙脑香叶的体外抗氧化活性(水提取物和水乙醇提取物(55% 水乙醇提取物))研究。这些提取物的体外抗氧化活性是通过使用 DPPH● 研究其抗辐射能力,然后研究其还原铁的能力,并测定其黄酮类化合物和总酚的含量来确定的。在感染了伤寒沙门氏菌(ATCC 6539)的 8 至 10 周龄的白化大鼠血浆和组织中测定了其体内抗氧化活性。这些受感染的大鼠同时接受了每日剂量的龙脑香提取物(10、20 和 51.84 mg/kg)和作为阳性对照的环丙沙星(14 mg/kg),共 15 天。治疗结束后,动物被处死,收集血液、肝脏、肾脏、心脏、肺脏、脾脏、睾丸和卵巢,以评估抗氧化剂参数,包括丙二醛、一氧化氮、过氧化氢酶和过氧化物酶,以及生物反应。在体外抗氧化测试中,55% 水乙醇提取物的 IC50 值最高(11.99 μg/ml)。在 200 μg/ml 时,该提取物的还原铁能力高于其他提取物。该提取物中黄酮类化合物和总酚的含量最高。该提取物(10、20 和 51.84 mg/kg)在治疗的第 8 至 12 天治愈了感染的大鼠。该提取物还能明显降低受感染大鼠血液中丙二醛和一氧化氮的含量,并能明显提高过氧化氢酶和过氧化物酶的活性。结果表明,Dracaena deisteliana 的叶提取物含有抗沙门氏菌和抗氧化物质,可用于治疗伤寒,降低沙门氏菌在大鼠感染过程中引起的氧化应激状态。大鼠感染 Typhi 时引起的氧化应激状态。
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引用次数: 0
Therapeutic Itinerary of Patients with Chronic Heart Failure at the Bafoussam Regional Hospital, West Region, Cameroon 喀麦隆西部大区巴富萨姆地区医院慢性心力衰竭患者的治疗路线
Pub Date : 2023-11-22 DOI: 10.9734/ijtdh/2023/v44i211493
Yimelong Tsayem Sibylle, Kouam Kouam Charles, Samuel Kingue, Nguemaim Flore Ngoufo, Mohamed Isah, Egbe Sangasu Eni, Misonge Kapnang Ivan, Sintieh N. N. Ekongefeyin
Background: Cardiovascular diseases have emerged as a growing public health problem worldwide, with heart failure being the end point of a greater majority of poorly diagnosed and managed heart diseases. In Sub-Saharan Africa, traditional medicine still has a remarkable influence on health care systems, and in Cameroon, the referral/counter-referral system thought to be implemented is not efficiently applied. Heart failure patients fall amongst the group of victims affected by this problem. Many studies have been carried on heart failure in Cameroon, but data on this subject remains sparse. Objective: To identify the therapeutic itinerary adopted by symptomatic patients with chronic heart failure seen at the Bafoussam Regional Hospital (BRH) and determine the outcome following management by cardiologists, so as to provide results-driven interventions to increase the rate of  early management of heart failure by appropriate health services and limit complications due to wrong therapeutic orientations. Methods: A hospital-based cross-sectional descriptive study was carried, from February 2019 to May 2019 at the Bafoussam Regional Hospital. A consecutive sampling technique using objective-related structured questionnaire was used to select patients aged above 18 years seen at the study site.  Data was analyzed using SPSS (Statistical Package for Social Sciences) version 23. A p-value less than 0.05 was considered statistically significant. Results: The BRH Cardiologist consultation was the 1st station sought by 32 (23.7%) of patients. We found 14.8% of cases and 8.9% who had as first therapeutic stations home management and traditional healers respectively. Majority of participants went through a total of 2 stations, 60 (44.4%), and only 5 (3.7%) went through 5 therapeutic stations. Most participants (36.3%), delayed for 1-3 weeks after onset of symptoms before seeking a means of intervention. NYHA (New York Heart Association) stages were generally improved after cardiologists’ follow up (54.1% and 26.7% for stages I and II respectively), compared to that before entry (0.7% stage I, 41.5% stage II, 38.5% stage 3, and 19.3% stage IV), which was statistically significant with P < 0.0005. Conclusion: There is a high proportion of HF patients who do no adopt an ideal therapeutic itinerary following the health pyramid from the onset of symptoms, hence the need to educate the population on cardinal signs of heart failure, especially patients with known risk factors, and to encourage the referral of patients in order to limit complications between the onset of symptoms till cardiologist consultation.
背景:心血管疾病已成为全球范围内日益严重的公共卫生问题,而心力衰竭是绝大多数诊断和管理不善的心脏病的终结点。在撒哈拉以南的非洲地区,传统医学对医疗保健系统仍有显著的影响,而在喀麦隆,人们认为已经实施的转诊/反转诊系统并未得到有效应用。心力衰竭患者就是受这一问题影响的受害者之一。关于喀麦隆心力衰竭的研究很多,但相关数据仍然很少。 研究目的确定在巴富萨姆地区医院(Bafoussam Regional Hospital,BRH)就诊的有症状的慢性心力衰竭患者所采取的治疗路线,并确定心脏病专家治疗后的结果,从而提供以结果为导向的干预措施,以提高通过适当的医疗服务对心力衰竭进行早期治疗的比率,并限制因错误的治疗方向而导致的并发症。 研究方法2019 年 2 月至 2019 年 5 月,在巴富萨姆地区医院开展了一项基于医院的横断面描述性研究。采用连续抽样技术,使用客观相关的结构化问卷,选择在研究地点就诊的 18 岁以上患者。 数据使用 SPSS(社会科学统计软件包)第 23 版进行分析。P 值小于 0.05 视为具有统计学意义。 结果32(23.7%)名患者的第一站是到 BRH 心脏科医生处就诊。我们发现,分别有 14.8% 和 8.9% 的病例将家庭治疗和传统疗法作为第一治疗站。大多数参与者(60 人,占 44.4%)总共进行了 2 次治疗,只有 5 人(3.7%)进行了 5 次治疗。大多数参与者(36.3%)在出现症状 1-3 周后才寻求干预手段。经心脏病专家随访后,NYHA(纽约心脏协会)分期普遍有所改善(I 期和 II 期分别为 54.1%和 26.7%),与随访前相比(I 期为 0.7%,II 期为 41.5%,3 期为 38.5%,IV 期为 19.3%),统计学意义显著,P < 0.0005。 结论有很高比例的心力衰竭患者从出现症状开始就没有按照健康金字塔采取理想的治疗路线,因此有必要教育民众了解心力衰竭的主要征兆,尤其是有已知危险因素的患者,并鼓励患者转诊,以减少从出现症状到心脏病专家会诊之间的并发症。
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引用次数: 0
Effect of Inhaling of Perfume on the Blood of Human Healthy Male Using Electrochemical Method by Cyclic Voltammetry 利用循环伏安法的电化学方法研究吸入香水对健康男性血液的影响
Pub Date : 2023-11-20 DOI: 10.9734/ijtdh/2023/v44i211491
H. J. Hassoon, M. Radhi, Asmaa Abdulsattar Obaid
All people in the world were used perfume in different manufactures and marker, in this study, we wanted to be found the effect of continues using of perfume and still inhaling these compound on the human healthy by electrochemical analysis using cyclic voltammetry. In the scientific knowledge, the inhaling of perfume by breathed and then reach to the blood stream through lungs and pulmonary alveoli passing to the blood vessels. The study focused on the   oxidation – reduction peaks current of the cyclic voltammogram which can be found from the perfume in healthy blood of male samples. It was found from the results that many oxidation peaks current appeared in the cyclic voltammogram in the blood medium with presence of the perfume, also, in different concentration, and different temperatures were studied, so all perfume compound were effected on the blood components of the male. The oxidative effect of the perfume on blood medium which may be caused the damage of blood components through the continuance of using it and appeared a risk cases of different diseases. the advices for correct using of the perfume in a little amount and in limited using every day, also avoid using the perfume to the patients with high fever.
在这项研究中,我们希望通过使用循环伏安法进行电化学分析,发现持续使用香水和继续吸入这些化合物对人体健康的影响。根据科学知识,吸入的香水通过呼吸,然后通过肺和肺泡到达血管进入血液。这项研究的重点是环形伏安图的氧化-还原峰电流,它可以从男性健康血液样本中的香水中发现。研究结果发现,在血液介质中存在香水的情况下,循环伏安图中出现了许多氧化峰电流,而且,在不同浓度和不同温度下进行了研究,因此所有香水化合物都对男性血液成分产生了影响。香水对血液介质的氧化作用可能会通过持续使用香水而导致血液成分的损坏,并出现不同疾病的风险病例。建议正确使用香水,每天使用少量和有限的香水,同时避免对高烧患者使用香水。
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引用次数: 0
Antibiotic Prescribing Practice in a Paediatric Outpatient Clinic in Owerri, Imo State, Nigeria 尼日利亚伊莫州奥韦里一家儿科门诊的抗生素处方实践
Pub Date : 2023-11-20 DOI: 10.9734/ijtdh/2023/v44i211492
E. Nwolisa, Udochukwuka Ikejiaku, J. Ezeogu, Kingsley Asinobi, K. Odinaka, Ezinne Nwankwo
Background: Antibiotics are amongst the most frequently prescribed drugs for children in outpatient clinics but irrational prescribing can cause medication errors, antibiotic resistance and treatment failure.  Examples of irrational prescribing includes poly-pharmacy, over use of injections, inappropriate use of antimicrobials and failure to prescribe in accordance with treatment guidelines. This study sought to assess antibiotic prescribing practice in the children’s outpatient clinic of the Federal university teaching hospital Owerri, Imo state. Materials and Methods: This was a descriptive prospective study carried out in the Children’s Outpatient Clinic (CHOP) of the Federal university teaching hospital Owerri, Imo state Nigeria between April and June 2021. During the study period, medical record of patients who attended the CHOP and who had antibiotic(s) prescribed were collated. Prescribing practice was assessed using the World Health Organization prescribing indicators. Results: A total of 495 antibiotic prescriptions were made for 478 patients.  This gave 1.04 as the average number of medicines prescribed per patient encounter.  1.6% of the antibiotics were prescribed as injections and 79.2% of the prescriptions were in generic names. While only 96.8% of the prescriptions were from the Nigerian essential drug list, the three most prescribed antibiotics Amoxicillin/Clavulanic acid, Cefuroxime and Amoxicillin are all listed in it. Conclusion: The antibiotic prescribing practice in the children’s outpatient clinic was rational with regards to average number of medications per patient encounter and percentage of encounters with injection prescribed.  It was irrational in terms of percentage of antibiotics prescribed in generic names and percentage of antibiotics prescribed from the Nigerian essential drug list.
背景:抗生素是门诊中最常给儿童开的药物之一,但不合理处方会导致用药错误、抗生素耐药性和治疗失败。 不合理处方的例子包括多药合用、过度使用注射剂、抗菌药物使用不当以及未按照治疗指南处方等。 本研究旨在评估伊莫州奥韦里联邦大学教学医院儿童门诊的抗生素处方实践。 材料与方法:这是一项描述性前瞻性研究,于 2021 年 4 月至 6 月期间在尼日利亚伊莫州奥韦里联邦大学教学医院儿童门诊(CHOP)进行。在研究期间,整理了在儿童门诊就诊并开具抗生素处方的患者的医疗记录。使用世界卫生组织的处方指标对处方实践进行了评估。 结果:共为 478 名患者开具了 495 份抗生素处方。 因此,每位患者平均处方 1.04 种药物。 1.6%的抗生素处方为注射剂,79.2%的处方为通用名。虽然只有 96.8% 的处方来自尼日利亚基本药物清单,但处方量最大的三种抗生素阿莫西林/克拉维酸、头孢呋辛和阿莫西林均列在清单中。 结论儿童门诊的抗生素处方做法在每次就诊的平均用药次数和注射处方的就诊百分比方面是合理的。 但从抗生素通用名处方比例和尼日利亚基本药物目录中抗生素处方比例来看,处方不合理。
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引用次数: 0
Knowledge and Utilization of the Glasgow Coma Scale (GCS) in Evaluating Unconscious Patients among Clinical Nurses in a Nigerian Referral Health Centre 知识和利用格拉斯哥昏迷量表(GCS)在评估昏迷患者在尼日利亚转诊保健中心的临床护士
Pub Date : 2023-09-07 DOI: 10.9734/ijtdh/2023/v44i161465
Galadima, A. U.
Introduction: Glasgow Coma Scale (GCS) is the foundation of the neurological appraisal of patients utilized by both nursing and clinical staff. The study was conducted to ascertain the level of knowledge, utilization and variables that prevent nurses using the GCS to evaluate unconscious patients at the teaching hospital of Modibbo Adama University in Yola, Adamawa state, Nigeria. Materials and Methods: The study utilized descriptive research cross-sectional design. the sample size for the study was calculated using Taro Yamane’s method, a structured questionnaire was administered to 131 respondents to collect data for the study out of which 117 were successfully filled and retrieved. Data collected was analysed and presented on tables. Finding: The findings revealed that more than half of the respondents (60%) were female with post basic nursing qualification, majority (61%) of the nurses surveyed were knowledgeable of GCS, 88% & 84% of respondents respectively reported that lack of knowledge regarding the GCS’s use and not having self-confidence regarding the application of GCS were the main factors that hindered them to their capacity to apply the GCS in their routine practice. Conclusion: It was concluded that the study subjects had good knowledge of GCS, so also utilization status of the GCS was very good. Recommendation: Based on the findings, it was recommended that Nurses must work harder to stay current with their knowledge and practice doing the GCS examination, and management should create an educational team to evaluate, instruct and make sure that nurses adhere to utilizing the GCS appropriately.
格拉斯哥昏迷量表(GCS)是护理人员和临床工作人员对患者进行神经系统评估的基础。该研究旨在确定尼日利亚阿达马瓦州约拉市莫迪博阿达马大学教学医院的护士使用GCS评估昏迷患者的知识水平、使用率和变量。材料与方法:本研究采用描述性研究横断面设计。本研究的样本量采用Yamane太郎的方法计算,对131名受访者进行了结构化问卷调查,以收集研究数据,其中117人成功填写并检索。对收集到的数据进行了分析并以表格形式呈现。结果:超过一半(60%)的受访护士为具有后基础护理资格的女性,61%的受访护士对GCS有所了解,88%和84%的受访护士分别表示对GCS的使用缺乏了解和对GCS的应用缺乏自信是阻碍其在日常实践中应用GCS的主要因素。结论:研究对象对GCS有较好的认识,对GCS的利用状况也较好。建议:根据调查结果,建议护士必须更加努力地保持他们在GCS检查方面的知识和实践,管理层应该建立一个教育团队来评估、指导和确保护士坚持正确使用GCS。
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引用次数: 0
The Knowledge and Utilization of Traditional Birth Attendants by Women in a Rural Community of Ilorin, Northern Nigeria 尼日利亚北部伊洛林农村社区妇女对传统助产士的知识和利用
Pub Date : 2023-09-05 DOI: 10.9734/ijtdh/2023/v44i161463
Lawal Abdulwahab, Salawu Wuraola, Makanjuola Oluwanifemi, Ambali Ambali, Alabi Oreoluwa, Kareem Ahmed, Chijindu Nwakama, Akande Maryam, Akande Tanimola, Al-Mansur Sumayya, Tijani Yusuf, Ahmed Mahmud, Aleem-Ghandi Taofeek, Adeyeye John, Nwafor Oni, Obateru Peace, Lawal Lukman
Background: One of the major factors contributing towards high maternal morbidity and mortality in many developing countries is the lack of access to skilled maternal healthcare services, as traditional birth attendants (TBAs) continue to serve as predominant providers of maternal healthcare in many rural communities. Aim: This study explores the knowledge and utilization of TBAs by women in a rural community, in order to identify healthcare gaps towards the provision of needed intervention. Study Design: This study is a descriptive cross-sectional study which was conducted in Alanamu community of Ilorin, northern Nigeria, in the year 2019. Methodology: A well-structured interviewer based questionnaire was administered to 212 women of reproductive age-group to collect data on their knowledge and utilization of the services of TBAs. Analysis was done using Statistical Product and Service Solutions (SPSS) software version 20. Results: One hundred and fifty three respondents (72.2%) had background knowledge of TBAs, 91 (40.8%) had visited a TBA at least once to carry out their deliveries, of which 73 (80.2%) of them had successful deliveries, 18 (19.8%) had complications during their deliveries, of which 7 (7.7%) were referred to health care facilities for expect management. The study showed statistical significance between the level of education of respondents and their patronage of TBAs with a P-value of .04. Conclusion: Our study showed adequate knowledge and utilization of the services of TBAs by members of the community. The use of TBAs has continued to thrive in this rural community especially among the uneducated population and has been associated with maternal complications. The integration of TBAs with standard healthcare system as well as continuous sensitization of the public on their roles and limitations would go a long way in reducing maternal morbidity and mortality associated with the use of untrained TBAs.
背景:在许多发展中国家,造成产妇发病率和死亡率高的主要因素之一是缺乏获得熟练产妇保健服务的机会,因为在许多农村社区,传统助产士仍然是主要的产妇保健提供者。目的:本研究探讨农村社区妇女对TBAs的知识和利用情况,以确定在提供所需干预措施方面的卫生保健差距。研究设计:本研究是一项描述性横断面研究,于2019年在尼日利亚北部伊洛林的Alanamu社区进行。方法:对212名育龄妇女进行问卷调查,了解她们对传统助产士服务的了解和利用情况。采用SPSS (Statistical Product and Service Solutions)软件进行分析。结果:153名受访妇女(72.2%)具有TBA背景知识,91名(40.8%)至少去过TBA一次分娩,其中73名(80.2%)分娩成功,18名(19.8%)分娩过程中出现并发症,其中7名(7.7%)转诊到卫生保健机构进行预期管理。研究显示,被调查者的受教育程度与他们对TBAs的赞助之间存在统计学意义,p值为0.04。结论:我们的研究表明社区成员对TBAs的服务有充分的了解和利用。在这个农村社区,特别是在未受教育的人口中,使用tba继续蓬勃发展,并与产妇并发症有关。将传统助产士与标准保健系统结合起来,并不断提高公众对其作用和局限性的认识,将大大有助于减少与使用未经训练的传统助产士有关的产妇发病率和死亡率。
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引用次数: 0
Determination of Plasmodial Species Prevalence among Patients Received at Cotonou Boni Clinic during Rainy Season in the Year 2022 2022年雨季科托努博尼诊所收治病人的疟原虫流行情况分析
Pub Date : 2023-09-05 DOI: 10.9734/ijtdh/2023/v44i161464
F. Tokponnon, R. Ossè, Jean Gille Egui, Gylchrist Houndjo, Zoulkifilou Sare Dabou, Festus Houessinon, Idayath Joachelle Gounou Yerima, Brice Fanou, M. Akogbéto
Aims: Malaria is a life-threatening disease caused by parasites transmitted by bites from infected female anopheles. It is a preventable and treatable illness. It remains a recurring disease among public health diseases that exposes many people to a risk of infection, including children under the age of 05 in Benin. Methods: To determine the prevalence of malaria and different plasmodial species at the Dr Pierre BONI Clinic, we performed venous and capillary samples on 731 patients for the realization of thick drops and blood smears between June and July 2022. Results: Three plasmodial species were identified in 228 patients (31%) as malaria of the 731 patients included in the study with 3 species of plasmodium found: Plasmodium falciparum (95.5%), Plasmodium malariae (2.85%), Plasmodium ovale (1.65%). Mixed or double species was also recorded in some patients: Plasmodium falciparum+ Plasmodium malariae and Plasmodium falciparum+ Plasmodium ovale. The majority of patients have the presence of trophozoites at Plasmodium falciparum, 95.5%.  The parasitic density of P. falciparum is higher than that of P. malariae and that of P. ovale. Conclusion: Although evaluated during a period of low transmission, malaria remains a real public health problem. The distribution of the disease is closely related to the presence in the blood of plasmodial species.
目的:疟疾是一种威胁生命的疾病,由受感染的雌性按蚊叮咬传播的寄生虫引起。这是一种可以预防和治疗的疾病。它仍然是公共卫生疾病中的一种反复出现的疾病,使许多人,包括贝宁的5岁以下儿童,面临感染的风险。方法:2022年6月至7月,我们对皮埃尔·博尼博士诊所731例患者进行静脉和毛细血管取样,实现浓滴和血涂片检测,以确定疟疾和不同疟原虫的流行情况。结果:在纳入研究的731例患者中,228例(31%)患者共检出3种疟原虫,其中恶性疟原虫(95.5%)、疟疾疟原虫(2.85%)、卵形疟原虫(1.65%)3种。部分患者出现恶性疟原虫+疟疾疟原虫、恶性疟原虫+卵形疟原虫等混合种或双种。大多数患者存在恶性疟原虫滋养体,占95.5%。恶性疟原虫的寄生密度高于疟疾疟原虫和卵形疟原虫。结论:虽然在低传播期进行了评估,但疟疾仍然是一个真正的公共卫生问题。该病的分布与血液中存在的疟原虫种类密切相关。
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引用次数: 0
Attitudes and Practices of Insecticide Treated Bed Nets Usage among Rural Dwellers in Oyo State, Nigeria 尼日利亚奥约州农村居民使用经杀虫剂处理的蚊帐的态度和做法
Pub Date : 2023-09-05 DOI: 10.9734/ijtdh/2023/v44i151462
N. C. Ekeleme, C. E. Ijioma, N. A. Unachukwu, P. I. Ejikem, J. E. Areh, C. I. Ogwu, E. O. Jeffery, I. J. Esangbedo, A. C. Amuta, P. C. Ojiri, N. O. Amoji, O. E. Aminu-Ayinde, E. S. Amadi, N. Onyeukwu, I. Abali, A. I. Airaodion
Aim: Malaria, a life-threatening disease transmitted to humans by the bites of infected female Anopheles mosquitoes, continues to be a significant public health issue, particularly in sub-Saharan Africa. This study was aimed at understanding the attitudes and practices regarding the use of insecticide-treated bed nets (ITNs) among rural dwellers in Oyo state, Nigeria. Methodology: The study adopted a cross-sectional design. The questionnaire was developed based on the objectives of the study. Sample size was calculated using the Fisher’s formula. The minimum sample size was 278 and was adjusted to 306 to account for non-response rate of 10%. A multi-stage cluster sampling technique was employed to select the participants. Results: The primary understanding of the purpose of ITNs was prevention of mosquito bites (59.67%), and prevention of malaria (40.33%). However, only 74% believed that ITNs could effectively prevent malaria and just 66% considered ITNs safe for use. The practice of ITN usage was quite high, with 93% of respondents possessing ITNs in their households. ITNs were obtained predominantly through free distribution (49%) or purchase (29.67%). Use of ITNs varied among participants, with 28.67% always using it, 41% often using it, and 7% never using it. The reasons for not always using ITNs included discomfort sleeping under it (49%) and perceptions of heat (30%). An analysis of the factors affecting the usage of ITNs indicated a significant association with the age, marital status, level of education, knowledge of ITNs, and beliefs about ITN's effectiveness and safety. The usage of ITNs was particularly low among younger respondents, those who were single or widowed/divorced/separated, those with no formal education or primary education, and those who were unaware of ITNs or did not believe in their effectiveness or safety. Conclusion: This study reveals a gap between knowledge and practice in ITN use, with significant barriers being discomfort and a lack of belief in the effectiveness of ITNs. While ownership rates are high, usage rates, especially consistent usage, is low. This was due to misconceptions, especially around the efficacy and safety of ITNs. Moreover, maintenance practices are suboptimal.
目的:疟疾是一种通过受感染的雌性按蚊叮咬传播给人类的威胁生命的疾病,它仍然是一个重大的公共卫生问题,特别是在撒哈拉以南非洲。这项研究的目的是了解尼日利亚奥约州农村居民对使用驱虫蚊帐的态度和做法。方法:本研究采用横断面设计。调查问卷是根据研究的目的编制的。样本量采用费雪公式计算。最小样本量为278例,考虑到10%的无反应率,调整为306例。采用多阶段整群抽样的方法进行调查。结果:对蚊帐目的的主要理解是预防蚊虫叮咬(59.67%),其次是预防疟疾(40.33%)。然而,只有74%的人认为ITNs可以有效预防疟疾,只有66%的人认为ITNs可以安全使用。使用个人信息网络的情况相当高,93%的受访者在家中拥有个人信息网络。itn主要通过免费分发(49%)或购买(29.67%)获得。参与者使用itn的情况各不相同,28.67%的人经常使用,41%的人经常使用,7%的人从不使用。不总是使用蚊帐的原因包括在蚊帐下睡觉不舒服(49%)和感觉热(30%)。对ITN使用影响因素的分析表明,年龄、婚姻状况、受教育程度、ITN知识以及对ITN有效性和安全性的信念与ITN使用有显著相关性。年轻的受访者、单身或丧偶/离婚/分居的受访者、没有受过正规教育或初等教育的受访者、不知道或不相信其有效性或安全性的受访者中,使用蚊帐的比例尤其低。结论:本研究揭示了ITN使用的知识和实践之间的差距,主要障碍是不适和对ITN有效性缺乏信心。虽然拥有率很高,但使用率,特别是一致性使用率很低。这是由于误解造成的,特别是对ITNs的有效性和安全性的误解。此外,维护实践是次优的。
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引用次数: 0
The Liver Function Score – “ALBI” Sets Apart Melioidosis, Scrub Typhus from Viral Hepatitis, Tuberculosis, Enteric Fever in a III-II Grade Score: Useful in Machine Learning and AI 肝功能评分-“ALBI”将类鼻疽病,恙虫病与病毒性肝炎,结核病,肠热区分为III-II级评分:在机器学习和人工智能中有用
Pub Date : 2023-09-04 DOI: 10.9734/ijtdh/2023/v44i151460
Sriram Kannan, Apoorva Pandey, Suchita Singh, Soumi Chowdhury, Venkat Abhiram Earny, Mohammed Ashiq, Vandana K. E., Chiranjay Mukhopadhyay, Harpreet Kaur
ALBI (Albumin-Bilirubin) score is routinely used in grading liver function of hepatocarcinoma and hepatitis patients. In this purposive review, the published values of serum albumin, bilirubin in Viral hepatitis, Tuberculosis, Scrub typhus, Enteric fever has been compared with that of melioidosis. Since PubMed yielded zero searches with key words “albumin, bilirubin, melioidosis”, it was searched in Google Scholar, a better retrievable search engine. This yielded 46 relevant  articles with 53 ALBI scores for Melioidosis. An equivalent search to retrieve 53 ALBI scores was made in Google Scholar for other confounding diseases of Melioidosis with search words “albumin, bilirubin, hepatitis” “albumin, bilirubin, tuberculosis”, “albumin, bilirubin, scrub typhus”, “albumin, bilirubin, enteric fever”. This raw data was deposited in Harvard dataverse  (https://doi.org/10.7910/DVN/QEW20J) and subsequent analysis done is documented in this article. This placed Melioidosis patients and Scrub typhus patients to be on an average grade III ALBI and the patients of Viral hepatitis, Tuberculosis, and Enteric fever in grade II ALBI. GRAPHICAL ABSTRACT
ALBI(白蛋白-胆红素)评分是肝癌和肝炎患者肝功能分级的常规方法。本文对病毒性肝炎、结核、恙虫病、肠热患者血清白蛋白、胆红素的测定值与类鼻疽的测定值进行了比较。由于PubMed以“白蛋白,胆红素,类melioidosis”为关键词的搜索结果为零,因此在谷歌Scholar(一个更好的检索引擎)中进行了搜索。这产生了46篇相关文章,53个类鼻疽的ALBI评分。在谷歌Scholar中搜索其他类鼻疽性混淆疾病,搜索词为“albumin, bilirubin, hepatitis”“albumin, bilirubin, tuberculosis”“albumin, bilirubin, scrub typhus”,“albumin, bilirubin, entericfever”,检索53个ALBI评分。这些原始数据保存在Harvard dataverse (https://doi.org/10.7910/DVN/QEW20J)中,本文记录了后续的分析。这使得类鼻疽患者和恙虫病患者的ALBI平均为III级,病毒性肝炎、结核病和肠热患者的ALBI平均为II级。图形抽象
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引用次数: 0
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International Journal of TROPICAL DISEASE &amp; Health
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