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Pharmaceutical Significance of Oxotungsten and Oxochromium Complexes of Schiff Bases Derived from Thiosemicarbazones 硫代氨基脲基席夫碱氧化钨和氧化铬配合物的药理意义
Pub Date : 2023-08-28 DOI: 10.9734/ijtdh/2023/v44i151457
Charu Khanna, Hemendra Gautam, R. Shukla
The thiosemicarbazones of bis(5-chlorosalicylaldehyde), bis(trifluoroacetylacetone), and their complexes with oxotungsten and oxochromium have been produced as metal complexes. These complexes have been identified by their IR, electronic, molar, and magnetic moment spectra. These studies have shown that the metal ion is surrounded by an octahedral geometry. Additionally, the complexes were examined for potential medicinal uses. Microbial agents acquiring drug resistant tendencies, have infected human beings, this research explores synthesis and characterization of these Schiff base metal complexes showing biological properties and were evaluated for their in-vitro anti-microbial activity. Antibacterial activity was examined by agar plate diffusion technique. Antifungal properties were examined by the radial growth method using agar-agar culture. The results show that activity increases on chelation. This activity is affected by the nature of substituents. This in relation to the lipophilicity of the ligands and their membrane permeability, is a key factor in determining their entry inside the cell.
以金属配合物的形式制备了双(5-氯水杨醛)、双(三氟乙酰丙酮)的硫代氨基脲及其与氧化钨、氧化铬配合物。这些配合物通过红外光谱、电子光谱、摩尔光谱和磁矩谱进行了鉴定。这些研究表明,金属离子被八面体几何结构所包围。此外,还研究了这些复合物的潜在药用价值。微生物制剂获得耐药倾向,感染了人类,本研究探索了这些具有生物学特性的希夫贱金属配合物的合成和表征,并对其体外抗菌活性进行了评价。采用琼脂平板扩散法检测其抑菌活性。采用琼脂培养的径向生长法检测其抗真菌性能。结果表明,螯合作用使活性增加。这种活性受取代基性质的影响。这与配体的亲脂性及其膜渗透性有关,是决定其进入细胞的关键因素。
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引用次数: 0
Risk Factors Associated with Diabetic Retinopathy among Patients Aged 50-75 Years Attending Diabetic Clinic at Mbagathi Hospital Nairobi County, Kenya 肯尼亚内罗毕县Mbagathi医院糖尿病门诊50-75岁患者糖尿病视网膜病变相关危险因素
Pub Date : 2023-08-28 DOI: 10.9734/ijtdh/2023/v44i151459
Tom Michira Nyakaba, D. Mogere, L. Koyio, Peterson Kariuki
Background: According to research, nearly 60% of persons with type 1 diabetes are likely to experience diabetes retinopathy after 20 years after the initial diagnosis of diabetes type 1. Nearly 40 % of all persons with unrestrained type 2 diabetes are likely to experience diabetes retinopathy during their lifetime. Objective: The study aimed to determine the risk factors associated with Diabetes Retinopathy among patients aged between 50 - 75 years seeking care at Mbagathi Hospital Nairobi County, Kenya. Method: This study used an analytical cross-sectional study design. A systematic random sampling design was used to recruit study partakers. The sample size for this study was 151 study respondents. Both Bivariate and binary logistic regression techniques were also utilized to evaluate the degree of association between the independent and the dependent variable. Statistical significance was set at p=<0.05. Results: The prevalence of diabetes retinopathy (non-proliferati ve diabetes retinopathy) in this study was 31.5% indicating this is a real public health concern that needs an urgent multisectoral approach. From this study, The presence of laboratory services (OR=10,95%CI=3.56-30.99), support group (OR=5.2,95%CI=1.81-14.85), provision of health care message (OR=11.6,95%CI=3.46-38.59), normal BMI (OR=3.6.95%CI=19.88-65.36) reduced the odds of diabetes retinopathy. Drinking alcohol (OR=22,95%CI=0.003-0.771), smoking (OR=33.95%, CI=0.004-0.262), uncontrolled blood sugars (OR=4,95%CI=19.89-65.36) increased the odds of diabetes retinopathy. Low education level (OR=5.9,95%CI=0.03-0.79), earning less than 6000 Ksh per month (OR=9,95%CI=0.04-0.29) smoking (OR=33.3,95%CI=0.004-0.262), uncontrolled blood sugars (OR=4,95%CI=19.89-65.36) increased the odds of diabetes retinopathy. Conclusion: The prevalence of diabetic retinopathy was high, earning less than 6000 Ksh per month, drinking alcohol, smoking, Low education level, and having uncontrolled blood sugars increased the odds of diabetes retinopathy. The presence of laboratory services, support group, provision of health care messages, and normal BMI reduced the odds of diabetes retinopathy
背景:根据研究,近60%的1型糖尿病患者在1型糖尿病初诊20年后可能会出现糖尿病视网膜病变。近40%的无约束2型糖尿病患者在其一生中可能会经历糖尿病视网膜病变。目的:本研究旨在确定在肯尼亚内罗毕县Mbagathi医院就诊的年龄在50 - 75岁之间的糖尿病视网膜病变患者的相关危险因素。方法:本研究采用分析性横断面研究设计。采用系统随机抽样设计招募研究参与者。本研究的样本量为151名研究受访者。双变量和二元逻辑回归技术也被用来评估自变量和因变量之间的关联程度。p=<0.05。结果:在这项研究中,糖尿病视网膜病变(非增殖性糖尿病视网膜病变)的患病率为31.5%,这表明这是一个真正的公共卫生问题,需要紧急采取多部门方法。在本研究中,实验室服务(OR=10,95%CI=3.56-30.99)、支持小组(OR=5.2,95%CI=1.81-14.85)、提供卫生保健信息(OR=11.6,95%CI=3.46-38.59)、正常BMI (OR=3.6.95%CI=19.88-65.36)降低了糖尿病视网膜病变的发生率。饮酒(OR=22,95%CI=0.003-0.771)、吸烟(OR=33.95%, CI=0.004-0.262)、血糖不控制(OR=4,95%CI=19.89-65.36)增加了糖尿病视网膜病变的发生几率。低教育水平(OR=5.9,95%CI=0.03-0.79)、月收入低于6000 Ksh (OR=9,95%CI=0.04-0.29)、吸烟(OR=33.3,95%CI=0.004-0.262)、血糖不控制(OR=4,95%CI=19.89-65.36)增加了糖尿病视网膜病变的发生几率。结论:糖尿病视网膜病变患病率高,月收入低于6000 Ksh、饮酒、吸烟、教育程度低、血糖不受控制增加了糖尿病视网膜病变的发生率。实验室服务、支持小组、提供保健信息和正常的BMI降低了糖尿病视网膜病变的几率
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引用次数: 0
Prevalence and Determinants of Undetectable Viremia among Recipients of Care Receiving HIV/AIDS Care in Akwa Ibom State, Nigeria 尼日利亚阿夸伊博姆州接受艾滋病毒/艾滋病护理的患者中无法检测到的病毒血症的患病率和决定因素
Pub Date : 2023-08-28 DOI: 10.9734/ijtdh/2023/v44i151458
R. Oladigbolu, D. Akpenna, C. Immanuel, E. Okwor, C. Ekeh, O. A. Akinjeji, P. Anyanwu, G. B. Obasa, F. Abbah, V. N. Nnanna, D. Iniama, P. Abah, C. Majekodunmi, Afamefune H. Nwafejeokwu
Background: Globally the benefits of undetectable viremia in preventing the transmission of HIV/AIDS have been established. Objective: The study aimed to assess the prevalence and determinants of undetectable viral load amongst HIV/AIDS clients receiving care and treatment in RISE-supported facilities in Akwa Ibom State, Nigeria. Methods: A descriptive cross-sectional study was conducted using secondary data from a validated Retention and Audit Determination Tool (RADET) file generated in September 2021. This was cleaned, imported into, and analyzed using a statistical package for social sciences (IBM SPSS) statistical package version 25. The prevalence of undetectable viremia was determined using descriptive statistics, and factors associated with undetectable viremia were assessed using chi-square analysis. Binary logistic regression was used to identify the determinants of undetectable viremia at an alpha level of <0.05 at a 95% confidence interval. Results: out of 47,575 recipients on care, 85.7% had undetectable viremia. Residing in rural areas (p<0.001, OR=1.3), respondents aged 25-49 years (p=0.008, OR=1.32), and those placed on Multi-Month Dispensing (MMD 6) (p<0.001, OR=1.45) were more likely to have undetectable viremia. While students (p=0.035, OR=1.2), and those employed (p=0.001, OR=1.102) were less likely to have undetectable viremia. Conclusion: This study reported a high prevalence of undetectable viremia. The determinants were occupation, residing in rural areas, productive age group, and being on MMD 6. Multiple interventions that include phone reminders and behavioral models to support self-care amongst urban dwellers are imperative. Differentiated interventions that include operation Triple Zero (OTZ) and Community Adolescent Treatment Supports (CATs) targeting the pediatric age group are needed to support the adherence to ART and undetectable viremia.
背景:在全球范围内,无法检测到的病毒血症在预防艾滋病毒/艾滋病传播方面的益处已经确立。目的:该研究旨在评估在尼日利亚阿夸伊博姆州rise支持的设施中接受护理和治疗的艾滋病毒/艾滋病患者中无法检测到的病毒载量的流行情况和决定因素。方法:使用来自2021年9月生成的经过验证的保留和审计确定工具(RADET)文件的辅助数据进行描述性横断面研究。使用社会科学统计包(IBM SPSS)统计包版本25对其进行清理、导入和分析。使用描述性统计确定不可检测病毒血症的患病率,使用卡方分析评估与不可检测病毒血症相关的因素。在95%的置信区间内,采用二元逻辑回归来确定无法检测到的病毒血症的决定因素,α水平<0.05。结果:在47,575名接受治疗的患者中,85.7%的患者存在无法检测到的病毒血症。居住在农村地区(p<0.001, OR=1.3)、25-49岁的应答者(p=0.008, OR=1.32)和使用多月配药(mmd6)的应答者(p<0.001, OR=1.45)更容易出现无法检测到的病毒血症。而学生(p=0.035, OR=1.2)和在职人员(p=0.001, OR=1.102)患无法检测到的病毒血症的可能性较小。结论:本研究报告了无法检测到的病毒血症的高患病率。决定因素是职业、居住在农村地区、生产年龄组和是否患有MMD。必须采取多种干预措施,包括电话提醒和行为模式,以支持城市居民的自我保健。需要有区别的干预措施,包括针对儿科年龄组的三零手术(OTZ)和社区青少年治疗支持(CATs),以支持坚持抗逆转录病毒治疗和无法检测到的病毒血症。
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引用次数: 0
Utilization of Reproductive Health Services and Associated Factors among Youths in Mombasa County, Kenya 肯尼亚蒙巴萨县青少年生殖健康服务的利用及其相关因素
Pub Date : 2023-08-21 DOI: 10.9734/ijtdh/2023/v44i141456
S. Yonge, B. Opiyo, Agnes W. Kibira, Rekha R. Sharma
Background: Reproductive health has become a global concern that is either poorly understood or not fully appreciated among the youth. Access to reproductive health services is important for protecting youth from STIs and unwanted pregnancy problems. Aim: The study sought to establish utilization of reproductive healthcare services and associated factors among youths in Mombasa County, Kenya.  Study Design: A descriptive cross-sectional study was carried out between August 2018 and January 2019.  Methodology: A self-administered, structured questionnaire was utilized to gather information. The information gathered was summarized using an SPSS database. The data was analyzed with SPSS version 22. Logistic regression was done to identify possible factors associated with reproductive health service utilization.  p-value less than 0.05 was considered as a level of significance.  Results: A total of 384 youth participated in the study, including 200 (62.2% females and 184 (37.8%) males. The media was the main source of information for modern family planning methods 200 (50. 1%). The majority of users 326 (84.9%) sought contraceptives from pharmacies. 213 (55.5%) were utilizing modern contraceptives. HIV/AIDS risk perception was significantly associated with utilization of reproductive health services [COR=2.34, 95% CI: 2.19-5.34].The condom was the most used method 134 (34.9%). Having knowledge about reproductive health services [COR=2.87; 95% CI: 1.92-3.94] was positively associated with the outcome. Male respondents were three (3) times more likely to use condoms [OR = 2.86, 95% Cl: 1.82-4.91] than female respondents. Conclusion: There was low uptake of contraceptive services among the youth who were sexually active. The condom was the most commonly used contraceptive. Strengthening urban healthcare systems is key to have equality and improve accessibility of FP services among the teenagers and young women.
背景:生殖健康已成为一个全球关注的问题,但青年对这一问题要么知之甚少,要么没有充分认识。获得生殖健康服务对于保护青年免受性传播感染和意外怀孕问题的侵害非常重要。目的:本研究旨在确定肯尼亚蒙巴萨县青少年生殖保健服务的利用情况及其相关因素。研究设计:一项描述性横断面研究于2018年8月至2019年1月进行。方法:采用自我管理的结构化问卷来收集信息。使用SPSS数据库对收集到的信息进行汇总。数据采用SPSS version 22进行分析。采用Logistic回归方法确定与生殖健康服务利用相关的可能因素。p值小于0.05为显著性水平。结果:共有384名青少年参与研究,其中女性200人(62.2%),男性184人(37.8%)。媒体是现代计划生育方法的主要信息来源。1%)。大多数使用者326(84.9%)从药店寻求避孕药具。213人(55.5%)使用现代避孕药具。艾滋病毒/艾滋病风险认知与生殖健康服务的利用显著相关[COR=2.34, 95% CI: 2.19-5.34]。安全套是使用最多的避孕方法134(34.9%)。了解生殖健康服务[COR=2.87;(95% CI: 1.92-3.94)与预后呈正相关。男性受访者使用安全套的可能性是女性受访者的3倍[OR = 2.86, 95% Cl: 1.82-4.91]。结论:性行为活跃的青少年对避孕服务的接受程度较低。避孕套是最常用的避孕工具。加强城市卫生保健系统是实现青少年和年轻妇女计划生育服务平等和改善其可及性的关键。
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引用次数: 0
Effect of Healthcare Facilities on Climate Change: A Systematic Review of the Carbon Footprint of the Nigerian Healthcare Sector 医疗保健设施对气候变化的影响:尼日利亚医疗保健部门碳足迹的系统审查
Pub Date : 2023-08-17 DOI: 10.9734/ijtdh/2023/v44i141455
Al-Mansur Sumayya, Adeniji Abdur-Rahman Adekunle, Tijani Yusuf Olatunji, Lawal Abdulwahab Oluwatomisin, Ogunleke Praise, Akin-Adewale Rolake, Shittu Rasheedat, Akande Maryam, Solagbade Remi Sanyolu
Background: Climate change has continued to pose a global concern, as the resulting effect of the increase in greenhouse gas (GHG) emissions continues to have significant consequences on the planet and its inhabitants. One of the major sectors contributing to the greenhouse effect is the healthcare sector, however, it is one of the sectors that has been overlooked and under reported. Objective: This article aims at reviewing the carbon footprint of healthcare facilities in Nigeria and its impact on climate change, while highlighting important and effective strategies towards addressing it. Methods: Data was obtained through a systematic review of available research articles obtained online via PubMed and Google scholar search engines, using the key words; climate change, healthcare facilities, global warming, and carbon footprint. Results: Effective policy and regulatory frame works are essential towards addressing the carbon footprint of healthcare facilities; however a lot of gap still exists in curbing the effect of GHG emissions by healthcare facilities in Nigeria, as majority of healthcare facilities in Nigeria still rely significantly on the combustion of fossil fuels for generation of power due to its epileptic electrical power supply. Conclusion: There is great need in addressing the effect of the carbon footprint of healthcare facilities on climate change. This can be achieved through the use of renewable energy technologies like solar and wind power, as well as the use of energy conservative measures such as the use of LED lighting and High-efficiency Heating, Ventilation, and Air Conditioning (HVAC) systems.
背景:由于温室气体(GHG)排放增加所产生的影响继续对地球及其居民产生重大影响,气候变化继续引起全球关注。造成温室效应的主要部门之一是医疗保健部门,然而,它是被忽视和报告不足的部门之一。目的:本文旨在审查尼日利亚医疗设施的碳足迹及其对气候变化的影响,同时强调解决这一问题的重要和有效战略。方法:系统回顾通过PubMed和谷歌学者搜索引擎在线获取的现有研究论文,使用关键词;气候变化、医疗设施、全球变暖和碳足迹。结果:有效的政策和监管框架对于解决医疗设施的碳足迹至关重要;然而,在遏制尼日利亚医疗保健设施温室气体排放的影响方面仍然存在很大差距,因为尼日利亚的大多数医疗保健设施仍然严重依赖燃烧化石燃料发电,因为其电力供应不稳定。结论:医疗卫生设施碳足迹对气候变化的影响亟须解决。这可以通过使用太阳能和风能等可再生能源技术,以及使用LED照明和高效采暖、通风和空调(HVAC)系统等节能措施来实现。
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引用次数: 0
Epidemiology of Candida Species Colonizing Mucosae of HIV-Infected Patients in Two Healthcare Centers of Cameroon During 2018-2020 2018-2020年喀麦隆两所卫生保健中心hiv感染者粘膜定殖念珠菌的流行病学
Pub Date : 2023-08-10 DOI: 10.9734/ijtdh/2023/v44i141453
C. Kountchou, Yves Somo Iwewe, D. Kamdem, Ekpo Alfred Itor, J. Dzoyem
Aims: This study aimed to investigate Candida species colonizing HIV-infected patients in Bafoussam and Yaounde in Cameroon. Study Design: Cross-sectional study. Place and Duration of Study: Yaoundé Central Hospital (YCH) and Bafoussam Regional Hospital (BRH) between October 2018 and December 2020. Methodology: We included 804 HIV-infected (681 women; 123 men; age range 21-81 years). Vaginal discharge, oral swab, stools, and urine were collected, and mycological diagnosis including direct macroscopic and microscopic analyses, culture on Sabouraud chloramphenicol medium, culture on chromogenic medium, germ tube test, evidence of chlamydospores production, biochemical analysis was performed. Yeast isolates were identified using matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS). Results: Eight hundred and four patients were recruited, and 2754 samples were collected. The colonization frequency was 17.35%, and 513 yeasts were isolated. Overall, Candida albicans 251 (48.92%) was the most frequently isolated. Non-albicans Candida (NAC) isolates have been classified into 16 species, including Candida krusei (14.23%), Candida glabrata (9.94%), Candida parapsilosis (8.18%), and Candida tropicalis (7.99%) as the major ones. There was a relationship (P-value= 0.00) between antiretroviral therapy and Candida species colonization. Conclusion: The results provide information on the epidemiology of Candida species in HIV-infected patients in Cameroon.
目的:调查喀麦隆巴富萨姆和雅温得地区hiv感染者的念珠菌菌种。研究设计:横断面研究。学习地点和时间:2018年10月至2020年12月,雅温顿中心医院(YCH)和巴福萨姆地区医院(BRH)。方法:我们纳入了804名艾滋病毒感染者(681名妇女;123人;年龄21-81岁)。收集阴道分泌物、口腔拭子、粪便和尿液,进行真菌学诊断,包括直接宏观和微观分析、沙伯罗德氯霉素培养基培养、显色培养基培养、胚管试验、衣孢子产生证据、生化分析。采用基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)对酵母菌分离物进行鉴定。结果:共招募患者884例,收集样本2754份。定植频率为17.35%,共分离到513株酵母菌。总体而言,白色念珠菌251(48.92%)是最常见的分离株。非白色念珠菌(NAC)分离株共分为16种,其中以克鲁氏念珠菌(14.23%)、光秃念珠菌(9.94%)、假丝念珠菌(8.18%)和热带念珠菌(7.99%)为主。抗逆转录病毒治疗与念珠菌定殖之间存在相关性(p值= 0.00)。结论:该结果为喀麦隆hiv感染者念珠菌的流行病学提供了信息。
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引用次数: 0
Profile of Oral Diseases and Associated Factors in the Elderly in the Buea Health District, Cameroon 喀麦隆布埃亚卫生区老年人口腔疾病及相关因素概况
Pub Date : 2023-08-04 DOI: 10.9734/ijtdh/2023/v44i141452
Tiayah Munge, P. J. Ngunde, K. O. Dzemo, Tendongfor Nicholas
Background: Demographic projections estimate a future global increase in the number of elderly with increase susceptibility to chronic and life-threatening diseases increases such as poor oral health conditions. This reduces quality of life, as it restricts food choices, affects esthetics and reduces self-esteem among the elderly. The aim of this study was to determine the profile of oral health pathologies of the elderly in the Buea Health District.   Materials and Methods: A cross- sectional study was conducted in four communities and major health facilities of the Buea Health District. Participants were interviewed to collect data on socio-demographic characteristics, determinants of oral health, and oral hygiene behavior.  Oral cavity examination was also carried out to assess the oral hygiene behavior of the elderly. The data was analyzed in SPSS version 26. Results: Out of 386 participants examined, 372 (96.4%) had at least one oral pathology. Dental caries was most prevalent (67.9%) with mean decay- missing- filled index (DMF) of 14.3 ± 8.7, followed by periodontitis (45.6%), gingivitis (45.6%) and edentulism (39.1%). Determinants of oral pathologies included tooth brushing frequency, health area, level of education, marital status and occupation. The mean score of oral hygiene behavior was 2.88±1.36, with 71.2% of participants with good oral hygiene behavior. There was a significant association between poor oral hygiene behavior and dental caries. Conclusion: There was a high prevalence of oral pathologies amongst the elderly of Buea Health District. Poor oral hygiene practice was associated with dental caries which was the most prevalent oral pathology.
背景:人口预测估计,未来全球老年人的数量将增加,他们对慢性和危及生命的疾病(如口腔健康状况不佳)的易感性将增加。这降低了生活质量,因为它限制了食物的选择,影响了审美,降低了老年人的自尊心。本研究的目的是确定老年人口腔健康病理的概况在布埃亚卫生区。材料和方法:在布埃亚卫生区的四个社区和主要卫生机构进行了一项横断面研究。对参与者进行访谈,以收集有关社会人口统计学特征、口腔健康决定因素和口腔卫生行为的数据。同时进行口腔检查,评估老年人口腔卫生行为。数据采用SPSS version 26进行分析。结果:在386名参与者中,372名(96.4%)至少有一种口腔病理。龋齿发生率最高(67.9%),平均龋缺补指数(DMF)为14.3±8.7,其次为牙周炎(45.6%)、牙龈炎(45.6%)和牙髓病(39.1%)。口腔疾病的决定因素包括刷牙频率、健康领域、教育程度、婚姻状况和职业。口腔卫生行为平均得分为2.88±1.36分,口腔卫生行为良好者占71.2%。不良的口腔卫生行为与龋齿之间存在显著的关联。结论:布埃亚卫生区老年人口腔疾病患病率较高。不良的口腔卫生习惯与龋齿有关,龋齿是最常见的口腔病理。
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引用次数: 0
Determinants of Community HIV Index Testing among HIV Index Clients in Yirol West County, South Sudan 南苏丹伊罗尔西县艾滋病毒指数检测人群中社区艾滋病毒指数检测的决定因素
Pub Date : 2023-08-02 DOI: 10.9734/ijtdh/2023/v44i131451
Zachariah Mabor Nyinypiu, D. Mogere, J. Mugo
Background: Index case HIV/AIDS testing  is a useful approach for addressing and enhancing the efficiency and yield of testing in high-risk populations among the high-risk groups for contracting HIV/AIDS partners and relatives of those existing with the disease. Objective: The research aimed to establish the determinants of community HIV index testing among HIV index clients in Yirol West County, South Sudan. Methods: The research employed an analytical cross-sectional research strategy, where a mixed approach entailing both questionnaire guides and interview guides were utilized. The sample size was premeditated using Fischer's formula where 252 study respondents were recruited in this study. The chi-square test and regression (logistic analysis) were applied to identify the determinants of community HIV clients index testing. For qualitative data, thematic analysis was carried out. While data collection took one month, the entire study consumed one year to be completed. Results: The utilization of community HIV index testing services was low in this study with only 24.2 % of the study respondents reporting utilizing these health services. Discussing HIV testing and counseling services (OR=3.3,95%CI=0.11-0.84),counseling to bring family members for HIV testing(OR=1.9,95%CI=0.29-0.97), and education level(OR=6.1,95%CI=0.04-0.65) was found to increase the odds of utilizing community HIV index testing. The presence of stigma (OR=8.3,95% CI=0.05-0.24) and lack of trust (OR=2,95%CI=0.27-0.96) among healthcare providers reduced the odds of utilizing community HIV index testing. Conclusion: The utilization of community HIV index testing services was low. Discussing HIV testing and counseling services, the status of marriage, gender, age, counseling to bring family members for HIV testing .and education level were found to increase the odds of utilizing community HIV index testing while the presence of stigma and discrimination, and duration lived with a partner lack of trust among health care providers reduced the odds of utilizing community HIV index testing. There is a need to put the necessary measures to enhance the increased uptake of community HIV index testing services.
背景:指数病例艾滋病毒/艾滋病检测是解决和提高高风险人群中艾滋病毒/艾滋病感染者的伴侣和亲属的检测效率和成果的有用方法。目的:研究南苏丹西伊罗尔县艾滋病毒感染者社区艾滋病毒指数检测的影响因素。方法:该研究采用了分析横断面研究策略,其中混合的方法包括问卷调查指南和访谈指南。样本量是预先使用费舍尔的公式,其中252研究的受访者在这项研究中招募。应用卡方检验和回归(逻辑分析)来确定社区HIV客户指数检测的决定因素。对定性数据进行了专题分析。虽然数据收集花了一个月的时间,但整个研究花费了一年的时间才完成。结果:本研究中社区艾滋病毒指数检测服务的使用率较低,只有24.2%的研究受访者报告使用这些卫生服务。讨论艾滋病毒检测和咨询服务(OR=3.3,95%CI=0.11-0.84)、咨询带家庭成员进行艾滋病毒检测(OR=1.9,95%CI=0.29-0.97)和教育程度(OR=6.1,95%CI=0.04-0.65)增加了利用社区艾滋病毒指数检测的几率。医疗服务提供者中存在的耻辱感(OR=8.3,95% CI=0.05-0.24)和缺乏信任(OR=2,95%CI=0.27-0.96)降低了使用社区HIV指数检测的几率。结论:社区艾滋病病毒指数检测服务使用率较低。讨论艾滋病毒检测和咨询服务、婚姻状况、性别、年龄、咨询带家庭成员进行艾滋病毒检测和受教育程度增加了利用社区艾滋病毒指数检测的几率,而存在耻辱和歧视以及与伴侣生活的时间缺乏卫生保健提供者的信任降低了利用社区艾滋病毒指数检测的几率。有必要采取必要措施,提高社区艾滋病毒指数检测服务的使用率。
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引用次数: 0
A Case of Hookworm Infection in a Child Causing Severe Anemia Diagnosed by Endoscopy: A Neglected Tropical Disease 内窥镜诊断儿童钩虫感染引起严重贫血一例:一种被忽视的热带病
Pub Date : 2023-07-29 DOI: 10.9734/ijtdh/2023/v44i131450
Romya Singh, Nidhi Tejan, Sabba Mussadiq, Awadhesh Kumar, Shikha Singh
Hookworm (Necator americanus, Ancylostoma duodenale) infection are common in tropical and subtropical countries. These are still an neglected tropical disease in rural areas,leading to severe iron deficiency anemia and even mortality. Here we present a case from a tertiary care center in northern India of a 3 year old child with progressive complaint of pallor and generalised body swelling. On upper gastrointestinal gastroscopy hookworms were visualised and recovered. Patients stool sample was sent to lab in which egg of hookworm was also seen on microscopy. The child was treated with albendazole and anemia was also cured
钩虫(美洲钩虫,十二指肠钩虫)感染在热带和亚热带国家很常见。在农村地区,这些疾病仍然是一种被忽视的热带病,导致严重缺铁性贫血,甚至死亡。在这里,我们提出一个病例,从三级保健中心在印度北部的一个3岁的儿童进行性投诉苍白和全身肿胀。在上消化道胃镜检查中发现并恢复了钩虫。将患者粪便样本送到实验室,显微镜下观察到钩虫卵。患儿接受阿苯达唑治疗,贫血也得以治愈
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引用次数: 0
Rice Grain Bursitis: Rare Manifestation of TB in Wrist Joint 米粒滑囊炎:结核在腕关节的罕见表现
Pub Date : 2023-07-19 DOI: 10.9734/ijtdh/2023/v44i131449
Isra Khan, S. Khalid, Emad Alvi, Sameera Khanam, S. Mohammad, M. Khalid
This case report highlights about rice grain bursitis- rare manfiestation of TB in wrist joint. Subacromial-subdeltoid bursitis of a shoulder with rice bodies is relatively uncommon. The understanding of the pathogenesis of rice body formation is yet approximate only but some clinical conditions like rheumatoid arthritis, tuberculous arthritis, seronegative inflammatory arthritis, juvenile rheumatoid arthritis and osteoarthritis are related to it. A 30yr Male patient presented with complaints of pain and swelling in the wrist joint , which was insidious in onset. It was associated with evening rise in temperature. Frequenetly erosion of the underlying bone, secondary osteomyelitis and median nerve encasement are present.
本病例报告强调稻米滑囊炎-罕见的结核在腕关节的表现。肩峰下-三角下滑囊炎伴米体是比较少见的。目前对稻体形成的发病机制尚不清楚,但类风湿关节炎、结核性关节炎、血清阴性炎症性关节炎、幼年型类风湿关节炎、骨关节炎等临床疾病均与稻体形成有关。一个30岁的男性患者提出的投诉疼痛和肿胀的手腕关节,这是潜伏的开始。这与夜间气温升高有关。经常出现底层骨侵蚀、继发性骨髓炎和正中神经包膜。
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引用次数: 0
期刊
International Journal of TROPICAL DISEASE &amp; Health
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