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Prevalence and Concentration of Airborne Microorganisms Isolated from Domestic Toilets in Port Harcourt, Rivers State, Nigeria 从尼日利亚里弗斯州哈科特港家庭厕所分离的空气传播微生物的流行率和浓度
Pub Date : 2024-03-07 DOI: 10.9734/ijtdh/2024/v45i41526
Agi V. N., Ollor O. A., Azike C. A., Chukwu G. C.
Introduction: Microorganisms are ubiquitous in nature and transient airborne microorganisms have been shown to constitute major health hazards. Aim: This study was carried out to assess the microbial air quality in ten (10) domestic toilets located in mile-3, Alakahia, Choba, Ada-George and Rumuokwuta, Port Harcourt, Rivers state, Nigeria. Methodology: Microbial air quality was sampled using sedimentation techniques. Freshly prepared Nutrient Agar, MacConkey and Sabouraud Dextrose Agar (SDA) plates were placed one meter above the floor of the toilets for 1 hours at different sections of each toilet exposed to an open air. The agar plates were closed and transported to the Laboratory were incubation took place at 37°C for 24 hours and 25°C for 3-5 days for growth of bacteria and fungi respectively. Isolates were characterized and identified by standard microbiological methods. Results: The bacteria isolated were Staphylococcus species 22(22.45%), Bacillus species 20 (20.41%), Enterococcus species 20(20.41%), Escherichia coli 16(16.32%), Micrococcus species 15 (15.31%), Klebsiella species 3(3.06%), and Proteus species 2(2.04%) while Aspergillus species 14(27.45%), Penicillium species 16(23.53%), Fusarium species 10(19.60%), Mucor species 8(15.69%), and Rhizopus species 7(13.73%) were the fungi identified. The highest bacteria colony count before and after flushing were 52.380×103CFU/m3/hr & 67.261× 103CFU/m3/ hrrespectively while the lowest bacteria counts observed before and after flushing 19.047× 103CFU/m3/hr & 39.286×103CFU/m3/hr while the highest and lowest fungal count before and after flushing were 10.119×103CFU/m3/hr & 13.690×103CFU/m3/hr and 5.952×103CFU/m3/hr & 5.953×103CFU/m3/hr respectively. Conclusion: This study shows that considerable numbers of both pathogenic bacteria and fungi particles were released into the air in higher quantity after flushing domestic toilets when compared to air quality before flushing. These organisms have been implicated in major and minor infectious diseases. Inhalation or contact may easily lead to infection especially in immunocompromised individuals and the older adults. To maintain the health of users, it is necessary to carefully manage the environmental factors that promote the growth and multiplication of microorganisms in domestic toilet environment.
导言:微生物在自然界中无处不在,瞬时传播的空气微生物已被证明对健康构成重大危害。目的:本研究旨在评估位于尼日利亚河流州哈科特港 mile-3、Alakahia、Choba、Ada-George 和 Rumuokwuta 的十(10)个家庭厕所的微生物空气质量。方法:使用沉降技术对空气中的微生物质量进行采样。将新鲜制备的营养琼脂、麦康凯琼脂和沙保葡萄糖琼脂(SDA)平板放在离厕所地面一米高的地方,在每个厕所暴露于露天的不同区域放置 1 小时。琼脂平板封口后运到实验室,分别在 37°C 和 25°C 温度下培养 24 小时和 3-5 天,以检测细菌和真菌的生长情况。采用标准微生物学方法对分离物进行特征描述和鉴定。结果:分离出的细菌有葡萄球菌 22(22.45%)、芽孢杆菌 20(20.41%)、肠球菌 20(20.41%)、大肠杆菌 16(16.32%)、微球菌 15(15.31%)、克雷伯菌 3(3.鉴定出的真菌有曲霉菌 14 种(27.45%)、青霉 16 种(23.53%)、镰刀菌 10 种(19.60%)、粘菌 8 种(15.69%)和根霉 7 种(13.73%)。冲洗前后的最高菌落数分别为 52.380×103CFU/m3/hr 和 67.261×103CFU/m3/hr,而冲洗前后的最低菌落数为 19.冲洗前后的最高和最低真菌计数分别为 10.119×103CFU/m3/hr 和 13.690×103CFU/m3/hr,以及 5.952×103CFU/m3/hr 和 5.953×103CFU/m3/hr。结论这项研究表明,与冲厕之前的空气质量相比,冲厕之后空气中释放的致病细菌和真菌微粒数量较多。这些有机物与主要和次要传染病有关。吸入或接触容易导致感染,尤其是免疫力低下的人和老年人。为了维护使用者的健康,有必要仔细管理促进家庭厕所环境中微生物生长和繁殖的环境因素。
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引用次数: 0
Natural Bioactive Compounds against Schistosoma haematobium and Schistosoma mansoni 抗血吸虫和曼氏血吸虫的天然生物活性化合物
Pub Date : 2024-03-04 DOI: 10.9734/ijtdh/2024/v45i31523
Aristide Ouattara, Harouna Sorè, Adama Zida
Aim: This documentary review aimed to make a synthesis of bioactive plants or natural compounds on schistosomes. We carried out a review from 2000 to 2022, oriented towards the plants in order to search natural compounds bioactive on schistosomes which can be a great contribution for new drugs discovering. Terms such as “schistosomiasis and medicinal plants”, “natural anti-schistosome compounds”, “phytochemical screening”, “bioactive compounds on schistosomes” were used for the online literature search through the following sites: PubMed; Google Scholar; ScienceDirect and Hinari. Results: There are many plants already used for the traditional treatment of schistosomiasis. This review found nearly 72 families of plants belonging to 228 botanical species have been listed. Some of these have been studied in vitro / in vivo and preliminary results have shown their schistosomicidal properties. Moreover, the results of qualitative phytochemical screening and toxicity testing of these natural compounds provide hope for new drug discoveries. Conclusion: Even if plants efficacy is proven, we need more in-depth investigations to determine their chemical components in order to minimize the undesirable effects and to guarantee their safety by assessing their toxicity.
目的:这篇文献综述旨在综述对血吸虫具有生物活性的植物或天然化合物。我们对 2000 年至 2022 年期间的植物进行了综述,目的是寻找对血吸虫具有生物活性的天然化合物,从而为新药的发现做出巨大贡献。我们使用了 "血吸虫病与药用植物"、"天然抗血吸虫化合物"、"植物化学筛选"、"血吸虫生物活性化合物 "等术语,通过以下网站进行在线文献检索:PubMed、Google Scholar、ScienceDirect 和 Hinari。结果有许多植物已被用于血吸虫病的传统治疗。本综述发现,有近 72 个植物科、228 个植物物种被列入其中。对其中一些植物进行了体外/体内研究,初步结果显示了它们的杀血吸虫特性。此外,这些天然化合物的定性植物化学筛选和毒性测试结果也为新药的发现带来了希望。结论:即使植物的功效已得到证实,我们仍需要进行更深入的研究,以确定其化学成分,从而最大限度地减少不良影响,并通过评估其毒性来保证其安全性。
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引用次数: 0
Mother’s Perception on Childbirth: Cesarean Section vs Normal Birth 母亲对分娩的看法:剖腹产与顺产
Pub Date : 2024-02-27 DOI: 10.9734/ijtdh/2024/v45i31521
Inke Malahayati, Zuraidah
Background: Cesarean section has increased from year to year. The 2018 Indonesia Basic Health Research found that the percentage of cesarean deliveries was 17.6% of 78.736 deliveries. It has almost twice from the 2013 Indonesia Basic Health Research of 9.8%. Various reasons were given by mothers for choosing cesarean section. Aims: To explore differences in mothers' perceptions of cesarean section and normal birth.  Here clearly write the aims of this study. Study Design: This study used a comparative study. Place and Duration of Study: This study was conducted in Simalungun Regency (North Sumatera, Indonesia) between July and September 2022. Methodology: We conducted on 106 women after 24 hours of labor (normal labor and cesarean section). Sampling was done by consecutive sampling. Data were collected using the Perception of Birth Scale/PBS questionnaire (29 questions) with a Likert scale of 1-5 and the Labor Agentry Scale/LAS (10 questions) with a Likert scale of 1-7 that had been translated and validated. Statistical test using Mann-Whitney U. Results: The mean PBS scores in the normal labor vs cesarean section group were 105.68 ± 10.95 and 109.09 ± 8.79 (p=0.026). The mean LAS score in the normal labor vs cesarean section group was 34.57 ± 5.27 vs 31.51 ± 4.37 (P value 0.000). Conclusion: Mothers who gave birth by cesarean section had a positive perception. Mothers who gave birth normally had high birth control. Education and information about the risks of the cesarean section should be promoted and mothers are supported to give birth naturally.
背景:剖宫产率逐年上升。2018 年印尼基本健康研究发现,在 78 736 例分娩中,剖宫产的比例为 17.6%。与2013年印尼基本健康调查的9.8%相比,几乎翻了一番。母亲们给出了选择剖宫产的各种原因。目的:探讨母亲对剖腹产和顺产的认知差异。 在此明确写出本研究的目的。研究设计:本研究采用比较研究法。研究地点和时间:本研究于 2022 年 7 月至 9 月期间在西马伦贡地区(印度尼西亚北苏门答腊)进行。研究方法:我们对 106 名分娩(顺产和剖腹产)24 小时后的产妇进行了研究。抽样采用连续抽样法。数据收集采用了经过翻译和验证的分娩感知量表/PBS 问卷(29 个问题)和分娩代理量表/LAS(10 个问题),前者采用 1-5 级李克特量表,后者采用 1-7 级李克特量表。统计检验采用 Mann-Whitney U:顺产组与剖宫产组的 PBS 平均得分分别为(105.68 ± 10.95)和(109.09 ± 8.79)(P=0.026)。顺产组和剖宫产组的平均 LAS 评分分别为(34.57 ± 5.27)和(31.51 ± 4.37)(P 值为 0.000)。结论剖宫产的母亲对分娩有积极的看法。正常分娩的母亲有较高的生育控制能力。应推广有关剖腹产风险的教育和信息,支持母亲自然分娩。
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引用次数: 0
Puerperal Sepsis and its Associated Factors: Review of Cases in a Tertiary Hospital in Jigawa, North-West Nigeria 产褥败血症及其相关因素:尼日利亚西北部吉加瓦一家三级医院的病例回顾
Pub Date : 2024-02-21 DOI: 10.9734/ijtdh/2024/v45i31520
Abdullahi Abba Habib, M. Ibrahim, Mubarak Abdulkareem Jabbo
Background: Puerperal sepsis is the 3rd leading cause of direct maternal death in developing countries. The case fatality rate of puerperal sepsis was reported to be as high as 8%, and it complicates 1-8% of all deliveries. It is an infection of the genital tract occurring anytime between the rupture of membranes and 42nd day postpartum.  Objective: The aim of the study was to determine the prevalence of puerperal sepsis and associated factors. Materials and Methods: This was a retrospective cross-sectional study carried out in the Department of Obstetrics and Gynecology of Rasheed Shekoni Federal University Teaching Hospital. The study participants were all the patients managed for puerperal sepsis during the period under review. The patients” data were collected using a structured proforma from their case files. Data obtained was analyzed with IBM SPSS version 21.0. Measured variables were expressed in descriptive statistics; mean ± SD for normally distributed quantitative variables, median and interquartile range for skewed quantitative variables. Qualitative variables were expressed in percentage and proportions. Results: The prevalence of puerperal sepsis was of 10.7%.  The mean age of the patients was 25.85 + 7.5. The mean parity was 3.89 + 4.5. Most (74.71%) of the women were unbooked and had home delivery (69.3%). Fever (90.7%) was the most frequent presenting complaints. The commonest (75.0%) organism cultured was staphylococcus aureus. Anemia was the commonest (63.6%) complication. Conclusion: The prevalence of Puerperal sepsis in this study is high. Low literacy level, unemployment, un-booked status and home delivery were found to be predisposing factors.
背景:在发展中国家,产褥败血症是导致产妇直接死亡的第三大原因。据报道,产褥败血症的病死率高达 8%,并发症占所有分娩的 1-8%。产褥败血症是一种生殖道感染,发生在胎膜破裂至产后第 42 天之间的任何时间。 研究目的本研究旨在确定产褥败血症的发病率及相关因素。材料和方法:这是一项在拉希德-谢科尼联邦大学教学医院妇产科进行的回顾性横断面研究。研究对象是在研究期间接受产褥败血症治疗的所有患者。使用结构化表格从病例档案中收集患者数据。获得的数据使用 IBM SPSS 21.0 版进行分析。测量变量用描述性统计量表示;正态分布的定量变量用均数±标准差表示,偏态的定量变量用中位数和四分位距表示。定性变量用百分比和比例表示。结果产褥败血症的发病率为 10.7%。 患者的平均年龄为 25.85+7.5 岁。平均胎次为 3.89 + 4.5。大多数产妇(74.71%)没有预约,在家中分娩(69.3%)。发热(90.7%)是最常见的主诉。最常见(75.0%)的细菌是金黄色葡萄球菌。贫血是最常见的并发症(63.6%)。结论本研究中产褥败血症的发病率很高。低文化水平、失业、未预约和在家分娩被认为是易发因素。
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引用次数: 0
Prevalence of Helicobacter pylori, Mycobacterium tuberculosis, Malaria Infections, and High Serum Prostate Specific Antigen Levels among Individuals at the Rivers State University, Nigeria: Findings of a Free Medical Outreach 尼日利亚河流州立大学学生幽门螺杆菌、结核分枝杆菌、疟疾感染和血清前列腺特异抗原水平偏高的患病率:免费医疗推广活动的结果
Pub Date : 2024-02-01 DOI: 10.9734/ijtdh/2024/v45i21515
I. Elekima, B. S. Mbeera, Thankgod Prince Ohaka, C. Azike, Onyemaechi Collins Micah, E. Nwokah, Onyemaechi Uchechukwu, V. N. Agi, Amarachi Bridget Ibuchim-Owabie, Chinyere Omereji-David, O. A. Ollor, Helen Waribo, I. George-Opuda, A. Ben-Chioma, Tombari Pius Monsi
Background: Co-morbidity of infections and non-infectious diseases is increasing in developing societies with little effort in identifying these trends. The study aimed to estimate the prevalence of Helicobacter pylori, Mycobacterium tuberculosis, malaria infections, and high serum prostate-specific antigen levels among individuals and residents at Rivers State University, Port Harcourt, Nigeria. Experimental Design: The study is a cross-sectional descriptive study, which consisted of 501 participants in a free medical outreach organized by the Association of Medical Laboratory Scientists of Nigeria, Rivers State University Chapter, Rivers State, Nigeria, in commemoration of the 2022 International Biomedical Day. The test subjects consisted of males and females, who were students, staff, and residents at the Rivers State University, Port Harcourt, Nigeria. The age range of the test subjects was 18-64 years. Methods: The cross-sectional descriptive study encompassed 501 adults (males and females) who gave consent for their blood screening during our free medical outreach. As a procedure, venous blood specimens were collected at the antecubital fossa from the attendees by venipuncture technique and were screened forH. Pylori antibody, Mycobacterium tuberculosis, malaria parasite, and prostate-specific antigen with the use of Accu-Tell rapid diagnostic test kits. Each test was read within 10 minutes. Red lines on the test zone and control zones of the test kits were read and recorded as positive cases, while a red line on the control zone and the absence of a red line on the test zone of the test kit were read, and recorded as negative case, in line with the rapid diagnostic manufacturer’s instructions. Results: Out of a total of 501 participants, the prevalence of H. pylori, M. tuberculosis, Plasmodium falciparum, and prostate-specific antigen were 9 (1.79 %), 3 (0.6 %), 12 (2.40 %), 6 (4.65 %%) respectively. The sex-based comparison showed that males have the same prevalence for all infectious diseases (H. pylori, M. tuberculosis, and P. falciparum) of 3 (2.32 %), and 6 (4.65 %) for a prostate-specific antigen. For the females, the prevalence of H. pylori, M. tuberculosis and P. falciparum were 6 (2.20 %), 0 (0.00 %), and 9 (2.42 %) respectively. Conclusion: M. tuberculosis prevalence was observed to be greater in the males than in the females of the studied population while that of H. pylori was observed to be higher in the females than the male participants. So continuous screening of the public to monitor and prepare them against the insurgence of these diseases which are of public health concern is important.
背景:在发展中社会,感染性疾病和非感染性疾病的并发率正在不断上升,但在确定这些趋势方面却鲜有作为。本研究旨在估算幽门螺杆菌、结核分枝杆菌、疟疾感染以及血清前列腺特异性抗原水平较高的个人和尼日利亚哈科特港河流州立大学居民的患病率。实验设计:本研究是一项横断面描述性研究,共有 501 人参加了由尼日利亚医学实验室科学家协会河流州立大学分会为纪念 2022 年国际生物医学日而组织的义诊活动。测试对象包括男性和女性,他们是尼日利亚哈科特港河流州立大学的学生、教职员工和居民。测试对象的年龄范围为 18-64 岁。研究方法这项横断面描述性研究包括 501 名成年人(男性和女性),他们在我们的免费医疗推广活动中同意接受血液筛查。按照程序,通过静脉穿刺技术在参会者的眶前窝采集静脉血标本,并对其进行幽门螺杆菌抗体、分枝杆菌和支原体筛查。使用 Accu-Tell 快速诊断试剂盒对幽门螺杆菌抗体、结核分枝杆菌、疟原虫和前列腺特异性抗原进行筛查。每次检测均在 10 分钟内读取结果。按照快速诊断试剂盒制造商的说明,在试剂盒的测试区和对照区读取红线并记录为阳性病例,而在对照区读取红线和在试剂盒的测试区没有红线则记录为阴性病例。结果在 501 名参与者中,幽门螺杆菌、结核杆菌、恶性疟原虫和前列腺特异性抗原的感染率分别为 9(1.79 %)、3(0.6 %)、12(2.40 %)和 6(4.65 %)。性别比较显示,男性在所有传染病(幽门螺杆菌、结核杆菌和恶性疟原虫)中的发病率相同,分别为 3(2.32 %)和 6(4.65 %)。女性幽门螺杆菌、结核杆菌和恶性疟原虫的感染率分别为 6(2.20 %)、0(0.00 %)和 9(2.42 %)。结论在研究人群中,男性的结核杆菌感染率高于女性,而女性的幽门螺杆菌感染率高于男性。因此,必须对公众进行持续筛查,以监测和防范这些与公共健康有关的疾病的肆虐。
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引用次数: 0
The Socioeconomic Impact: Assessing the Risk and Burden of Malaria on Vulnerable Populations in Kenya 社会经济影响:评估疟疾给肯尼亚弱势群体带来的风险和负担
Pub Date : 2024-02-01 DOI: 10.9734/ijtdh/2024/v45i21516
Thomas Opiyo Okumu
This paper seeks to explore the significance and impact of malaria on Kenya’s economic growth. This will help to understand the impact that malaria has or have had on household economic status especially for the vulnerable population in Kenya and how it has been unfolding slowly over time. This will also seek to understand the coping strategies adopted by the said population and the negative implications that have influenced these household’s abilities to withstand malaria and other eventualities that may happen in the future. The risk and burden of malaria on vulnerable population together with its economic effects have been presented. Search engines such as Google Scholar and PubMed as well as related economics and medical journals were instrumental for this study. To protect the poor and vulnerable population against these adverse effects of malaria and from malaria itself, there is a great need to draft and enact policies that will be able control the effects as well as integration development and poverty reduction programs. The future work and focus for government and all stakeholders should be to focus more energy and work on achievable health services that will eliminate the burden of health especially malaria and its effects on Kenyan economic activities undertaken by the vulnerable population and to address the burden and risk of malaria on the productive under privileged within their environment, as well as study the epidemiological and socio-economic geographical dissimilarities of the vulnerable population and the normal population.
本文旨在探讨疟疾对肯尼亚经济增长的意义和影响。这将有助于了解疟疾对家庭经济状况,尤其是肯尼亚弱势群体的家庭经济状况已经或已经产生的影响,以及这种影响是如何随着时间的推移而缓慢发展的。这还将有助于了解上述人群所采取的应对策略,以及影响这些家庭抵御疟疾和未来可能发生的其他事件的能力的负面影响。疟疾对弱势人群造成的风险和负担及其经济影响已得到介绍。谷歌学术、PubMed 等搜索引擎以及相关的经济学和医学期刊对本研究很有帮助。为了保护穷人和弱势群体免受疟疾的不利影响以及疟疾本身的危害,亟需起草和颁布能够控制疟疾影响以及整合发展和减贫计划的政策。政府和所有利益相关者今后的工作和重点应该是将更多的精力和工作放在可实现的保健服务上,以消除健康负担,特别是疟疾及其对肯尼亚弱势人口所从事的经济活动的影响,解决疟疾对其所处环境中的生产性弱势群体造成的负担和风险,以及研究弱势人口和正常人口在流行病学和社会经济地理方面的差异。
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引用次数: 0
National Surveillance Data on the Epidemiology of Meningitis in Niger, 2005 - 2020 2005-2020 年尼日尔脑膜炎流行病学全国监测数据
Pub Date : 2024-01-24 DOI: 10.9734/ijtdh/2024/v45i21514
Alkassoum S. I., Abdoulaye Z., Goni A., Amadou O., Djibo A., Emoud T., Ibrahim M. L., Adeossi E.
Background: Bacterial meningitis is a major public health problem, especially in low-income countries. We analyzed national surveillance data and isolates from Niger to describe the epidemiology of bacterial meningitis from 2005 to 2020. Methods: We conducted a retrospective study of nationwide case-based surveillance data of all reported meningitis cases in Niger from 2005 to 2020. Modified case definition was used to classify the cases. Results: A total of 47,953 suspected meningitis cases and 3,276 deaths (CFR=6.83%) were reported, corresponding to an incidence of 189.01 cases per 100,000 population. The male represented 55.41% ( sex-ratio male : female = 1.30) and 40.52% were 5 -14 y. A total of 29,998 cases were reported through RNL, of which 10,979 (36.60%) were confirmed, of which 6,149 (56.01%), were confirmed by culture. The predominant organism identified was N. meningitidis serogroup A (33.91%). All regions reported meningitis cases and a consistent and substantial reduction was seen in confirmed NmA cases, with no cases occurring in the country after the completion of mass campaigns. Nevertheless, other pathogen species and Nm variants, including NmX, NmC, and Streptococcus pneumoniae, have become more prevalent. Conclusion: Increased surveillance of multiple serogroups throughout is necessary, as well as consideration of vaccination with combination vaccines rather than just using a single strain as is currently the case with NmA.
背景:细菌性脑膜炎是一个重大的公共卫生问题,尤其是在低收入国家。我们分析了尼日尔的国家监测数据和分离物,以描述 2005 年至 2020 年细菌性脑膜炎的流行病学。研究方法我们对 2005 年至 2020 年尼日尔所有报告脑膜炎病例的全国病例监测数据进行了回顾性研究。采用修改后的病例定义对病例进行分类。研究结果共报告 47953 例疑似脑膜炎病例和 3276 例死亡病例(CFR=6.83%),发病率为每 10 万人 189.01 例。通过 RNL 报告的病例共有 29,998 例,其中 10,979 例(36.60%)得到确诊,6,149 例(56.01%)通过培养得到确诊。经鉴定的主要病原体是脑膜炎奈瑟菌 A 血清群(33.91%)。所有地区都报告了脑膜炎病例,经确诊的 NmA 病例持续大幅减少,在大规模宣传活动结束后,全国没有出现任何病例。然而,其他病原体种类和 Nm 变体(包括 NmX、NmC 和肺炎链球菌)变得更加流行。结论有必要在各地加强对多种血清群的监测,并考虑使用联合疫苗接种,而不是像目前 NmA 那样只使用单一菌株。
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引用次数: 0
Socio-economic Correlates of Intestinal Helminthiasis Infestation in Children with Human Immunodeficiency Virus Presenting in the University of Nigeria Teaching Hospital, Ituku-ozalla, Enugu 埃努古伊图库-奥扎拉尼日利亚大学教学医院人类免疫缺陷病毒感染儿童肠道螺旋体感染的社会经济相关因素
Pub Date : 2024-01-17 DOI: 10.9734/ijtdh/2024/v45i11512
Onyia Jo, Onyia Oa, Nzeduba Cd, Maduka Nc, Agu G, Chime P, Asinobi In, Chinawa Jm
Background: Children infected with Human Immunodeficiency virus (HIV) may be more prone to helminthic infestation and this may be modified by their socio-demographic and hygiene-related variables.Objectives: This study was aimed at eliciting the various socioeconomic correlates that affect helminth infections among children with HIV and comparing it with their normal counterparts who had no HIV.Methods: A cross-sectional study where a total of 140 subjects including 70 HIV-infected children and 70 children without HIV infection. They were consecutively recruited from the Paediatric HIV clinic and matched for age and sex with.Results: Socio-economic class, area of residence, hygienic practices such as method of feacal disposal, hand washing practices and footwear practices were significantly associated with helminthic infestation at the bivariate level of analysis (p < 0.05). Using bivariate analysis, of the independent variables that were significant at the bivariate analysis, only lower socioeconomic class was an independent predictor of helminthic infestation (AOR = 6.403, 95% CI: 1.303 to 31.469)Conclusion: Socio-demographic and hygiene-related risk factors are similar in HIV-positive and negative children. However, lower socioeconomic status is an independent predictor of helminthic intestinal infestation after controlling for potential confounders such as age and gender.
背景:感染了人类免疫缺陷病毒(HIV)的儿童可能更容易受到蠕虫感染,而这可能会受到他们的社会人口和卫生相关变量的影响:本研究旨在了解影响艾滋病毒感染儿童蠕虫感染的各种社会经济相关因素,并将其与未感染艾滋病毒的正常儿童进行比较:这项横断面研究共有 140 名受试者,包括 70 名感染 HIV 的儿童和 70 名未感染 HIV 的儿童。这些儿童是从儿科艾滋病诊所连续招募的,年龄和性别与未感染艾滋病的儿童相匹配:社会经济阶层、居住地区、卫生习惯(如粪便处理方法、洗手习惯和穿鞋习惯)在二元分析水平上与蠕虫感染显著相关(p < 0.05)。通过双变量分析,在双变量分析中显著的自变量中,只有较低的社会经济阶层是螺旋体感染的独立预测因素(AOR = 6.403,95% CI:1.303 至 31.469):艾滋病毒抗体阳性和阴性儿童的社会人口和卫生相关风险因素相似。然而,在控制了年龄和性别等潜在混杂因素后,较低的社会经济地位是螺旋体肠道感染的一个独立预测因素。
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引用次数: 0
Regional Variation in Chikungunya Viral Infection Prevalence in Meghalaya: A Study from Tertiary Teaching Center from North East India 梅加拉亚邦基孔肯雅病毒感染流行率的地区差异:印度东北部高等教学中心的一项研究
Pub Date : 2024-01-16 DOI: 10.9734/ijtdh/2024/v45i11511
S. Agarwal, Cleopatra K. Shadap, W. V. Lyngdoh, K. Lyngrah, Manika Agarwal
Aim: The aim of the study is to investigate the sero-prevalence of chikungunya presented within NEIGRIHMS (North Eastern Indira Gandhi Regional Institute of Health and Medical sciences), a regional institute located in Shillong, Meghalaya, India. Study Design: This was a cross-sectional study. Place and Duration of the Study: The study was carried out in NEIGRIHMS covering patients within Meghalaya apart from the Garo Hills, India, during the months of June to November,              2023. Methodology: Blood samples from patients were collected and were subjected to CHIKV IgM ELISA for detection of chikungunya virus infection. A total of 100 samples (46 males and 54 females; age range: 18 above) from patientswith chikungunya-like symptoms commonly fever, arthralgia, myalgia and headache were recruited for the study. Results: Out of 100 samples tested for CHIKV IgM Elisa, 10 samples came out positive. Conclusion: An active surveillance of cases and identification of their sources can help to identify where the resources for chikungunya prevention program should be distributed within the state of Meghalaya for optimum utilization of resources and effective disease control.
目的:本研究旨在调查位于印度梅加拉亚邦新隆市的东北英迪拉-甘地健康与医学科学地区研究所(NEIGRIHMS)内基孔肯雅病的血清流行率。研究设计:这是一项横断面研究。研究地点和时间:研究于 2023 年 6 月至 11 月期间在印度梅加拉亚邦除加罗山以外的其他地区进行。研究方法:采集患者血液样本,并采用 CHIKV IgM ELISA 检测基孔肯雅病毒感染。研究共收集了 100 份样本(46 名男性和 54 名女性;年龄范围:18 岁以上),这些样本来自具有基孔肯雅病类似症状的患者,这些症状通常包括发烧、关节痛、肌痛和头痛。研究结果在对 100 份样本进行的 CHIKV IgM Elisa 检测中,10 份样本呈阳性。结论积极监测病例并确定病例来源有助于确定梅加拉亚邦预防基孔肯雅病计划的资源分配,从而优化资源利用和有效控制疾病。
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引用次数: 0
Prevalence and Predictors of Depression among Medical Students of Imo State University, Owerri, South Eastern Nigeria. 尼日利亚东南部奥韦里伊莫州立大学医学生抑郁症的患病率和预测因素。
Pub Date : 2023-12-22 DOI: 10.9734/ijtdh/2023/v44i241507
Oluoha R. U., Offiong A. A., Okafor P. N., Nwaigbo Ernest, Nwachukwu Ifeanyi
Background: Depression has been recognized as one of the significant public health problems of the 21st century. Previous studies have revealed higher prevalence of psychological morbidity among medical students in comparison to their age – matched non – medical counterparts. Objective: This study evaluated the prevalence and predictors of depression among medical students of Imo State University, Owerri, South Eastern Nigeria. Methods: An institution based cross – sectional survey was conducted among 180 medical students selected using a systematic sampling technique. Data collection was with the aid of a pretested semi – structured self – administered questionnaire. Prevalence of depression was assessed using a modified Depression, Anxiety and Stress Scale (DASS – 21). Data was analysed using Statistical Package for Social Sciences (SPSS), version 22. Descriptive statistics was presented using summary indices, frequency tables and percentages. Associations between variables were done using the Chi –square and logistic regression. A p – value of < 0.05 was considered statistically significant. Results: The mean age of the respondents was 26.9 ± 4.1 years. Only 10.6% of the students were very well informed about depression with social media (45.9%) as the main source of information. The prevalence of depression in this study was 41.2%. Sociodemographic variables significantly associated with depression were body mass index (p < 0.0001) and psychoactive substance use (p < 0.0001). Being overweight (OR = 8.41) or obese (OR = 4.25) were significant predictors of depression. Likewise, respondents who often (OR = 8.50) or always (OR = 7.40) use psychoactive substances were significantly more likely to be depressed in comparison to those who do not. Conclusion: Depression is a burning public health problem among medical students. There is need for institutional reforms to help address depression among medical students. Also, majority of students getting information about depression from social media is indicative of the fact that they are not getting adequate exposure to Psychiatry. In view of this, review of the medical curriculum should be considered.
背景:抑郁症已被认为是 21 世纪重大的公共卫生问题之一。以往的研究显示,与年龄匹配的非医学生相比,医学生的心理疾病发病率更高。 研究目的本研究评估了尼日利亚东南部奥韦里伊莫州立大学医学生抑郁症的患病率和预测因素。 方法: 以院校为单位进行横断面调查:采用系统抽样技术在 180 名医科学生中进行了一项基于院校的横断面调查。数据收集采用了预先测试的半结构化自填问卷。采用改良的抑郁、焦虑和压力量表(DASS - 21)对抑郁症患病率进行评估。数据使用社会科学统计软件包(SPSS)第 22 版进行分析。使用汇总指数、频率表和百分比进行描述性统计。变量之间的关联采用卡方检验和逻辑回归检验。P 值小于 0.05 视为具有统计学意义。 结果受访者的平均年龄为 26.9 ± 4.1 岁。只有 10.6% 的学生非常了解抑郁症,而社交媒体(45.9%)是主要的信息来源。本研究中抑郁症的患病率为 41.2%。体重指数(p < 0.0001)和使用精神活性物质(p < 0.0001)是与抑郁症明显相关的社会人口变量。超重(OR = 8.41)或肥胖(OR = 4.25)是抑郁症的重要预测因素。同样,经常(OR = 8.50)或总是(OR = 7.40)使用精神活性物质的受访者与不使用精神活性物质的受访者相比,患抑郁症的几率明显更高。 结论抑郁症是医学生中一个紧迫的公共卫生问题。有必要进行体制改革,以帮助解决医学生中的抑郁症问题。此外,大多数学生从社交媒体上获取有关抑郁症的信息,这表明他们没有充分接触精神病学。有鉴于此,应考虑对医学课程进行审查。
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引用次数: 0
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International Journal of TROPICAL DISEASE &amp; Health
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