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A Comparative Study of 137 Cs Dose Factors for Constant and Depth-dependent Soil Densities. 土壤密度恒定与深度相关137Cs剂量因子的比较研究。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-01-01 Epub Date: 2025-05-09 DOI: 10.1097/HP.0000000000001995
Necati Çelik, Nilay Akçay, Uğur Çevik

Accurate assessment of external radiation dose rates from 137 Cs is essential for evaluating radiological risk in environmental and occupational settings. This study refines dose conversion coefficient calculations by incorporating depth-dependent soil density and addressing limitations in conventional methods that assume constant soil density. We calculated dose conversion coefficients for 137 Cs in soil, considering both exponential and Gaussian distributions of activity concentration. Using two models, one with constant density and another with variable density as a function of depth, we compared dose rates to quantify the effect of soil density variations. Results indicate that dose rates are consistently higher when depth-dependent density is applied. The effect is more pronounced when 137 Cs activity is distributed over larger depths (i.e., greater relaxation lengths) or when broader Gaussian distributions are considered. This suggests that assuming constant soil density may lead to underestimations of dose rates, especially in heterogeneous or compacted soils. Our findings emphasize the importance of accounting for density variability in dose calculations to enhance radiological risk assessments for areas contaminated with 137 Cs.

摘要:准确评估137Cs外辐射剂量率对于评估环境和职业环境中的辐射风险至关重要。本研究通过纳入与深度相关的土壤密度和解决假设土壤密度恒定的传统方法的局限性,改进了剂量转换系数的计算。考虑土壤中137Cs活性浓度的指数分布和高斯分布,计算了土壤中137Cs的剂量转换系数。使用两个模型,一个是恒定密度,另一个是变密度作为深度的函数,我们比较了剂量率,以量化土壤密度变化的影响。结果表明,当应用与深度相关的密度时,剂量率始终较高。当137Cs活度分布在更大的深度(即更大的松弛长度)或考虑更宽的高斯分布时,效果更为明显。这表明,假设土壤密度恒定可能会导致剂量率的低估,特别是在非均匀或压实的土壤中。我们的研究结果强调了在剂量计算中考虑密度变异性对加强137Cs污染地区的放射风险评估的重要性。健康物理杂志,129(0):000-000;2025.
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引用次数: 0
Insights into Testicular Radiation Exposure in the Orthopedic Surgeon. 对骨科医生睾丸辐射暴露的认识。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-01-01 Epub Date: 2025-05-07 DOI: 10.1097/HP.0000000000001993
Taylor K Zak, Stephan Zmugg, Daniel Bouton, Jennifer Rodgers, Vivek Kalia, Neil Stewart, Jordan Polk, Kaitlyn Brown, Yassine Kanaan, Anthony I Riccio

Testicular radiation exposure has been linked to diminished spermatogenesis, male infertility, and potentially testicular cancer. Despite this, the risk of testicular exposure from intraoperative fluoroscopy to the male orthopedic surgeon has yet to be studied. The purpose of this study is to determine factors associated with unnecessary testicular radiation exposure in male orthopedic surgeons. The study was designed to answer the following questions: (1) Do the designs of lead apron protection result in any differential testicular radiation exposure? (2) Does the position of the surgeon (standing, sitting, and knee position while sitting) alter the amount of testicular radiation exposure? (3) Does any combination of lead apron design and surgeon positioning increase the degree of testicular radiation exposure? A life-sized, whole-body, anthropomorphic phantom simulating an orthopedic surgeon was positioned adjacent to a hand table attached to a standard radiolucent operating table. A digital dosimeter was attached to the groin region beneath a lead apron. Scatter radiation dose equivalent rates were measured during continuous anteroposterior C-arm fluoroscopy of a forearm/hand phantom. Four trials were conducted using three different types of protective lead aprons (cross-back, full-skirt, and half-skirt) in three different positions (standing, sitting with knees 10 cm apart, and sitting with knees 25 cm apart). Radiation dose-equivalent rates were compared using the Student's t-test and analysis of variance. No scatter radiation (measured value of 0.0 mrem min -1 [0.0 Sv min -1 ]; below minimum detectability of dosimeter) was detected underneath the lead aprons in the standing position and when sitting with the knees 25 cm apart, using all three types of lead. When sitting with the knees 10 cm apart, the mean dose equivalent rate of scatter radiation was higher using the half-skirt (0.01 mrem min -1 [0.000001 Sv min -1 ]) than the cross-back (below minimum detectability of dosimeter) and skirt aprons (below minimum detectability of dosimeter), but this did not reach statistical significance (p = 0.44). For all apron types and all positions, the use of an apron resulted in significantly less scatter radiation exposure when compared to no protection (p < 0.001). Protective lead aprons are effective at preventing testicular radiation exposure in both the standing and sitting positions. As the only detectable radiation exposure occurred with use of a half-skirt apron when sitting with the knees spread 10 cm apart, cross-back and full-skirt aprons may provide slightly enhanced protection over half-skirt aprons in the sitting position.

摘要:睾丸辐射暴露与精子发生减少、男性不育和潜在的睾丸癌有关。尽管如此,术中透视对男性骨科医生睾丸暴露的风险还有待研究。本研究的目的是确定与男性骨科医生不必要的睾丸辐射暴露有关的因素。本研究旨在回答以下问题:(1)铅围裙防护的设计是否会导致睾丸辐射暴露的差异?(2)外科医生的体位(站立、坐着和坐着时的膝盖位置)是否会改变睾丸辐射暴露量?(3)铅围裙的设计和外科医生的体位是否会增加睾丸的辐射暴露程度?一个真人大小的、全身拟人化的模拟整形外科医生的假体被放置在一个连接到标准放射手术台上的手台上。一个数字剂量计连接在腹股沟区域铅围裙下面。在前臂/手幻影的连续正位c臂透视期间测量散射辐射剂量当量率。采用三种不同类型的保护性铅围裙(横背式、全裙式和半裙式)在三种不同的姿势(站立、两膝相距10厘米坐着、两膝相距25厘米坐着)下进行了四项试验。使用学生t检验和方差分析比较辐射剂量当量率。无散射辐射(实测值0.0 mrem min-1 [0.0 Sv min-1];使用三种类型的铅,在站立位置和坐着时,在铅围裙下检测到低于剂量计最小可检测值的铅。双膝相距10 cm坐姿时,穿半裙(0.01 mrem min-1 [0.000001 Sv min-1])的平均散射辐射剂量当量率高于穿背(低于剂量计最小可探测性)和围裙(低于剂量计最小可探测性),但差异无统计学意义(p = 0.44)。对于所有围裙类型和位置,与不防护相比,使用围裙导致的散射辐射暴露显著减少(p < 0.001)。铅护圈在站立和坐姿时都能有效防止睾丸受到辐射。由于唯一可检测到的辐射暴露发生在双膝分开10厘米坐着时使用半裙围裙时,交叉背围裙和全裙围裙可能比坐着时使用半裙围裙提供略微增强的保护。
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引用次数: 0
Measurement of Effective Half-life of Iodine-131 to Optimize Safety Release Instructions after Treatment for Patients with Differentiated Thyroid Cancer. 测量碘-131的有效半衰期以优化分化型甲状腺癌患者治疗后的安全释放说明。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-01-01 Epub Date: 2025-05-30 DOI: 10.1097/HP.0000000000001997
Timothy Greist, Aaron Smith

Iodine-131 ( 131 I) is a common therapy for treatment of differentiated thyroid carcinoma (DTC); however, its radioactivity poses a radiation safety risk to public health. There is inter-facility variation in release instructions to minimize incident exposure to other individuals. Isolation measures are not without harm. Most studies on this topic rely upon cumulative dosimetry to measure exposure, but this does not provide the researcher with critical dose protraction information. Refining estimation of elimination kinetics with more frequent exposure readings would help optimize radiation safety recommendations. Measuring radiation exposure from patients with DTC post-thyroidectomy receiving 131 I would better quantify its elimination kinetics to improve radiation safety recommendations. Patients with DTC post-thyroidectomy undergoing radioiodine remnant ablation with 131 I were instructed to measure exposure at a distance of 1 m, three times a day for 14 d, using an ion chamber at home. These data were used to form an exponential decay model and estimate the time after which cumulative exposure is below a reasonably low threshold. The average effective half-life was 15.8 h when calculated using real-time exposure readings from 32 patients. Among patients administered less than 4.22 GBq, cumulative effective dose is ≤1 mSv after 24 h of isolation. Between 4.22 and 6.03 GBq, cumulative effective dose is ≤1mSv after 48 h of isolation. Cumulative gamma radiation exposure at 1 m remains low enough to consider re-evaluating isolation protocols that encourage long-term distancing past the first 24 h in post-thyroidectomy patients treated with 131I for remnant ablation.

摘要:碘-131 (131I)是治疗分化型甲状腺癌(DTC)的常用药物;然而,其放射性对公众健康构成辐射安全风险。为了尽量减少事故对其他人员的暴露,各设施之间的释放指令有所不同。隔离措施并非没有危害。关于这一主题的大多数研究依赖于累积剂量法来测量暴露,但这并不能为研究人员提供关键的剂量延长信息。用更频繁的暴露读数来改进消除动力学的估计将有助于优化辐射安全建议。测量甲状腺切除术后DTC患者接受131I的辐射暴露可以更好地量化其消除动力学,从而改进辐射安全建议。DTC甲状腺切除术后接受放射性碘残留消融131I的患者被指示在家中使用离子室测量1 m距离的暴露量,每天三次,持续14天。这些数据被用来形成指数衰减模型,并估计累积暴露低于合理低阈值的时间。根据32例患者的实时暴露读数计算,平均有效半衰期为15.8小时。在剂量小于4.22 GBq的患者中,隔离24小时后累积有效剂量≤1 mSv。在4.22 ~ 6.03 GBq之间,隔离48 h后累积有效剂量≤1mSv。累积1 m的伽马辐射暴露仍然足够低,可以考虑重新评估隔离方案,鼓励甲状腺切除术后接受131I残余消融治疗的患者在最初24小时后保持长期距离。
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引用次数: 0
pyDOSEIA: A Python Package for Radiological Impact Assessment during Long-term or Accidental Atmospheric Releases. pyDOSEIA:用于长期或意外大气释放期间辐射影响评估的Python软件包。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-01-01 Epub Date: 2025-11-24 DOI: 10.1097/HP.0000000000002014
Biswajit Sadhu, Tanmay Sarkar, S Anand, Kapil Deo Singh, D K Aswal

pyDOSEIA is a Python package designed for meteorological data processing and radiological impact assessment in diverse scenarios, including nuclear and radiological accidents. Built upon robust computational models and using modern programming techniques, pyDOSEIA employs the Gaussian Plume Model and follows IAEA and AERB guidelines, offering a comprehensive suite of tools for estimating radiation doses from various exposure pathways, including inhalation, ingestion, groundshine, submersion, and plumeshine. The package enables age-specific, distance-specific, and radionuclide-specific radiation dose computations, providing accurate and reliable calculations for both short-term and long-term exposures. Additionally, pyDOSEIA leverages up-to-date dose conversion factors, features parallel processing capabilities for rapid analysis of large datasets, and facilitates applications in machine learning and deep learning research. With its user-friendly interface and extensive documentation, pyDOSEIA empowers researchers, practitioners, and policymakers to assess radiation risks effectively, aiding in decision making and emergency preparedness efforts. The package is open-source and available on GitHub at https://github.com/BiswajitSadhu/pyDOSEIA .

摘要:pyDOSEIA是一个Python软件包,专为各种场景下的气象数据处理和辐射影响评估而设计,包括核事故和辐射事故。pyDOSEIA建立在强大的计算模型和使用现代编程技术的基础上,采用高斯羽流模型,并遵循IAEA和AERB的指导方针,提供了一套全面的工具来估计各种暴露途径的辐射剂量,包括吸入、摄入、地面照射、淹没和羽流照射。该软件包能够计算特定年龄、特定距离和特定放射性核素的辐射剂量,为短期和长期照射提供准确可靠的计算。此外,pyDOSEIA利用最新的剂量转换因子,具有并行处理能力,可快速分析大型数据集,并促进机器学习和深度学习研究中的应用。通过用户友好的界面和广泛的文档,pyDOSEIA使研究人员、从业人员和决策者能够有效地评估辐射风险,帮助决策和应急准备工作。该软件包是开源的,可以在GitHub上获得https://github.com/BiswajitSadhu/pyDOSEIA。
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引用次数: 0
Radiation Dose Reconstruction Using Q-Band EPR Analysis of Mini-biopsy Dental Enamel Samples. 用q波段EPR分析微活检牙釉质样品的辐射剂量重建。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-01-01 Epub Date: 2025-11-24 DOI: 10.1097/HP.0000000000002041
Lekhnath Ghimire, Edward Waller

This study focuses on recent advancements in biodosimetry using continuous wave (CW) Q-band electron paramagnetic resonance (EPR) spectroscopy and mini-biopsy samples from tooth enamel. When radiation is absorbed, the carbonate impurities in enamel (i.e., hydroxyapatite) are changed into •CO2- (carbon dioxide radical anions), which become trapped within the crystal lattice and remain stable for durations far exceeding human lifespans. This stability makes tooth enamel an ideal material for assessing radiation doses in both accident and retrospective scenarios. In contrast to traditional, more invasive CW X-band EPR (9.8 GHz) methods, the CW Q-band EPR technique allows for the non-invasive (or minimally invasive) collection of smaller enamel fragments. This enables faster, more comfortable sampling. Operating at approximately 34 GHz, CW Q-band EPR offers enhanced sensitivity and a significantly improved signal to noise ratio (S/N) compared to CW X-band EPR. This increased sensitivity is crucial for detecting lower radiation doses in smaller samples, making it particularly useful for accurately identifying high-risk individuals in radiation triage situations. For this study, mini biopsies weighing around 2 mg were extracted from teeth and analyzed at room temperature using CW Q-band EPR. Calibration curves were established using reference doses, allowing the precise calculation of doses from signal intensity. Radiation doses higher than 100 mSv were estimated with high precision and accuracy. The combination of CW Q-band EPR spectroscopy and mini-biopsy sampling of tooth enamel provides a rapid, reliable method for dose assessment in radiation triage scenarios. This advancement is essential for developing efficient biodosimetry techniques, enabling the timely identification and management of individuals exposed to ionizing radiation during radiation incidents. Additionally, this method proves invaluable for retrospective dose reconstruction in cases of chronic exposure applicable to individuals, groups, or entire populations.

本研究的重点是使用连续波q波段电子顺磁共振(EPR)光谱和牙釉质微型活检样本进行生物剂量测定的最新进展。当辐射被吸收时,牙釉质中的碳酸盐杂质(即羟基磷灰石)转变为•CO2-(二氧化碳自由基阴离子),它们被困在晶格中,并在远远超过人类寿命的时间内保持稳定。这种稳定性使牙釉质成为在事故和回顾性情况下评估辐射剂量的理想材料。与传统的更具侵入性的CW x波段EPR (9.8 GHz)方法相比,CW q波段EPR技术允许非侵入性(或微创性)收集更小的牙釉质碎片。这使得更快,更舒适的采样。工作频率约为34 GHz,与连续波x波段EPR相比,连续波q波段EPR具有更高的灵敏度和显著改善的信噪比(S/N)。这种增加的灵敏度对于在较小的样本中检测较低的辐射剂量至关重要,使其在辐射分诊情况下准确识别高风险个体特别有用。在本研究中,从牙齿中提取重量约为2 mg的微型活组织,并在室温下使用CW q波段EPR进行分析。使用参考剂量建立校准曲线,允许根据信号强度精确计算剂量。对高于100毫西弗的辐射剂量进行了高精度和准确的估计。连续波q波段EPR光谱和牙釉质显微活检的结合为辐射分诊场景中的剂量评估提供了一种快速、可靠的方法。这一进展对于开发有效的生物剂量测定技术至关重要,能够在辐射事件中及时识别和管理暴露于电离辐射的个体。此外,该方法对于慢性照射病例的回顾性剂量重建非常宝贵,适用于个人、群体或整个人群。
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引用次数: 0
Fractional Deposition of Radioactive Aerosols in the Respiratory Tract: Effects of Anatomical and Physiological Differences between Chinese and Caucasians. 放射性气溶胶在呼吸道的分散沉积:中国人和白种人解剖和生理差异的影响。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-01-01 Epub Date: 2025-11-24 DOI: 10.1097/HP.0000000000001999
Lai Zhou, Yuanyuan Liu, Bin Wu, Xiangpeng Meng, Yu Wang, Ao Ju, Jianping Cheng

For the calculation of fractional deposition of radioactive aerosols, the deposition model in ICRP Publication 130 has been widely used. However, the deposition model is based on the anatomical and physiological characteristics of Caucasians. Since physiology and anatomical parameters of Chinese differ from those of Caucasians, this difference can affect the applicability of depositional models to Chinese people. ICRP suggests that the corresponding parameters can be replaced when the parameters of concerned people are known. Therefore, this paper investigates the physiological and anatomical parameters of Chinese people and establishes a respiratory deposition model applicable to Chinese people. It is found that the dependence of fractional deposition on aerosol particle size on Chinese people is qualitatively similar to that in Caucasian people. However, the value of fractional deposition is quantitatively different. When the AMAD (activity median aerodynamic diameter) is 1 μm (public exposure), the ratio of fractional deposition between Chinese and Caucasian light workers could reach up to 1.22 in the AI region, and the ratios of fractional deposition in other regions also ranged from 0.87-0.93; when the AMAD is 5 μm (occupational exposure), the ratio of fractional deposition between Chinese and Caucasian light workers could reach up to 1.35 in the AI region, and the ratios of fractional deposition in other regions also ranged from 0.95-1.30. The fractional deposition is used as input to biokinetic models to simulate the transport of radionuclides through the body after inhalation and ultimately impacts the dose conversion factor calculations.

摘要:对于放射性气溶胶的分级沉降计算,ICRP第130号出版物中的沉降模型得到了广泛的应用。然而,沉积模型是基于白种人的解剖和生理特征。由于中国人的生理和解剖参数与高加索人不同,这种差异会影响沉积模式对中国人的适用性。ICRP建议,当相关人员的参数已知时,可以替换相应的参数。因此,本文通过调查中国人的生理解剖参数,建立适用于中国人的呼吸沉积模型。研究发现,中国人的气溶胶颗粒大小对气溶胶分级沉降的依赖性与高加索人的相似。然而,分数沉积的价值在数量上是不同的。当活动中值空气动力直径(AMAD)为1 μm(公众暴露)时,中国光工与白种人光工在AI地区的分数沉积比最高可达1.22,其他地区的分数沉积比也在0.87 ~ 0.93之间;当AMAD为5 μm(职业暴露)时,AI地区华裔光工与白种人光工的分数沉积比最高可达1.35,其他地区的分数沉积比也在0.95 ~ 1.30之间。分数沉积被用作生物动力学模型的输入,以模拟吸入后放射性核素在体内的运输,并最终影响剂量转换因子的计算。
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引用次数: 0
Differences between Radiation Dose Values under Wearing and Non-wearing Geometries of Personal Dosimeters during Sleep. 睡眠中佩戴与不佩戴个人剂量计几何形状下辐射剂量值的差异。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-01-01 Epub Date: 2025-06-16 DOI: 10.1097/HP.0000000000002001
Jun Hirouchi, Shogo Takahara, Masatoshi Watanabe

With the return of residents after the Fukushima Daiichi Nuclear Power Station accident, the measurement results of radiation doses to residents can be used to assess the risk or safety of remaining in their homes. However, personal radiation doses vary depending on the behavior and residential environment of each subject, even for a group of subjects living in the same region at the same time. In past studies, subjects were required to wear a personal dosimeter on their chests outdoors, but they were not required to wear the device indoors. This study investigated the difference between the dose values indicated for the wearing and non-wearing geometries of personal dosimeters during sleep. In particular, an adult human phantom was used to compare the indicated dose values when personal dosimeters were placed on the chest (reproducing the wearing geometry) and near the head (reproducing the non-wearing geometry) in two houses with a high measured radiation dose. Furthermore, to understand the reason for the difference in the indicated dose values, the radiation dose rate during sleep was calculated using a radiation transport calculation code. The dose values for the wearing geometry were approximately 4% lower on the first floor and approximately 15% lower on the second floor than those for the non-wearing geometry. In addition, the radiation dose rates and radiation dose rate ratios (head/chest) differed by approximately 30% and 20%, respectively, depending on the distance from the nearest window (1 to 3 m).

摘要:福岛第一核电站事故发生后,随着居民陆续返回家园,居民辐射剂量测量结果可用于评估居民留在家中的风险或安全性。然而,个人辐射剂量取决于每个受试者的行为和居住环境,即使是同一时间生活在同一地区的一组受试者也是如此。在过去的研究中,受试者被要求在户外胸前佩戴个人剂量计,但不要求在室内佩戴。本研究探讨了睡眠期间佩戴和不佩戴个人剂量计几何形状所显示的剂量值之间的差异。特别是,在两个高辐射测量剂量的房屋中,使用成人幻影来比较个人剂量计放在胸部(再现佩戴几何形状)和靠近头部(再现非佩戴几何形状)时的指示剂量值。此外,为了了解指示剂量值差异的原因,使用辐射传输计算代码计算睡眠期间的辐射剂量率。磨损几何结构的剂量值在一楼比不磨损几何结构的剂量值低约4%,在二楼比不磨损几何结构低约15%。此外,辐射剂量率和辐射剂量率比(头部/胸部)分别约有30%和20%的差异,这取决于与最近窗口的距离(1至3米)。
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引用次数: 0
Radiation Doses and Lifetime Attributable Risk of Cancer in Sweden after the Chernobyl Nuclear Power Plant Accident. 切尔诺贝利核电站事故后瑞典的辐射剂量和癌症的终生归因风险。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-01-01 Epub Date: 2025-06-13 DOI: 10.1097/HP.0000000000001998
Martin Tondel, Katja Gabrysch, Mats Isaksson, Christopher Rääf

Methods for estimating radiological consequences in terms of radiation doses and cancer risks are needed for informed decisions on mitigation efforts after a radionuclide event. The 1986 Chernobyl Nuclear Power Plant accident fallout in Sweden was used as a case study. Open-source data on annual sex-specific population data in 1-y classes by municipality (n = 290), counties (n = 21), and future projection were retrieved from Statistics Sweden from 1986 to 2035. Published organ dose coefficients, cancer risk coefficients, and established methods for dose calculations and cancer risk projections were applied to estimate organ absorbed doses (mGy), effective dose (mSv), collective dose (person-Sv), and lifetime attributable risk (LAR). Due to the geographically variable Chernobyl fallout in Sweden, the variability in absorbed organ doses was greater between municipalities and counties than between organs or sexes. LAR was translated into 377 male and 448 female extra cancer cases over 50 y post-Chernobyl. Overall, 38% of these cancer cases could be attributed to the internal dose in males and 32% in females. The highest number of cancer cases was estimated for Västernorrland county, with only 3% of the Swedish population in 1986, but 18% of the excess cancer cases 1986 to 2035. The collective dose was calculated to 6,028 person-Sv, whereas 2,148 person-Sv (36%) was internal dose. Like for LAR, the population of Västernorrland county got 18% of the total collective dose. The excess number of cancer cases derived from LAR and collective dose gave similar results. Our methods can be adopted to other countries and different fallout scenarios.

摘要:放射性核素事件发生后,需要在辐射剂量和癌症风险方面评估辐射后果的方法,以便在知情的情况下做出缓解努力的决策。1986年瑞典切尔诺贝利核电站事故的放射性尘埃被用作案例研究。从1986年到2035年,从瑞典统计局检索了按直辖市(n = 290)、县(n = 21)和未来预测的1-y年级年度性别人口数据的开源数据。已发表的器官剂量系数、癌症风险系数和已建立的剂量计算和癌症风险预测方法被用于估计器官吸收剂量(mGy)、有效剂量(mSv)、集体剂量(人-西沃特)和终生归因风险(LAR)。由于瑞典切尔诺贝利放射性尘降物的地理差异,不同市和县之间吸收器官剂量的差异大于不同器官或性别之间的差异。在切尔诺贝利事故后的50年里,LAR被翻译成377名男性和448名女性额外的癌症病例。总的来说,这些癌症病例中有38%可归因于男性的内剂量,32%可归因于女性的内剂量。据估计,癌症病例数最高的是Västernorrland县,1986年仅占瑞典人口的3%,但1986年至2035年的超额癌症病例占18%。集体剂量为6028人西沃特,而内剂量为2148人西沃特(36%)。与LAR一样,Västernorrland县的人口获得了总集体剂量的18%。LAR和集体剂量导致的过量癌症病例数给出了类似的结果。我们的方法可以适用于其他国家和不同的放射性尘降情景。
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引用次数: 0
HEALTH PHYSICS SOCIETY . 2025 AFFILIATE MEMBERS. 健康物理学会。2025个附属会员。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-01-01 Epub Date: 2025-11-24 DOI: 10.1097/01.HP.0001174608.53040.2c
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引用次数: 0
Cobalt: An Update Review from Biokinetic and Toxicological Data to Treatment after Internal Exposure. 钴:从生物动力学和毒理学数据到内暴露后治疗的最新综述。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-01-01 Epub Date: 2025-06-27 DOI: 10.1097/HP.0000000000002005
Géraldine Landon, Céline Bouvier-Capely, François Fay, Elias Fattal, Guillaume Phan

Cobalt is an essential element with a wide range of applications. It is made up of one stable isotope ( 59 Co) and 36 radioactive isotopes, including 60 Co, the only one with a half-life of more than one year. It is an activation product, and irradiation is the main mode of exposure to 60 Co. Nevertheless, the risk of internal contamination should not be overlooked, particularly for workers who may be involved in maintenance tasks in nuclear power plants or on dismantling sites. The general population may also be affected in the event of a reactor accident where 60 Co would be released with other radionuclides. The health effects of exposure to stable cobalt are mainly respiratory and cutaneous. However, the recently revealed carcinogenic nature of certain cobalt compounds calls for vigilance. Otherwise, the radiotoxicity of cobalt has not yet been explored. In view of the many uses of cobalt and the potential exposures identified, effective means of protection for humans and their environment are of paramount importance. To date, in the event of incorporation by inhalation, ingestion, or cutaneous injury, the current pharmacological treatments offer perfectible efficacy. This review article outlines an updated state of knowledge on cobalt, with a special focus on its biokinetic and toxicological data, the recommended medical countermeasures, and the research in progress in this field. Finally, this review suggests new research perspectives, particularly in the field of medical countermeasures, an area of utmost importance in terms of radiation protection and occupational health.

摘要:钴是一种具有广泛用途的必需元素。它由一种稳定同位素(59Co)和36种放射性同位素组成,其中60Co是唯一一种半衰期超过一年的同位素。它是一种活化产物,辐照是60Co的主要暴露方式。然而,内部污染的危险不应被忽视,特别是对于可能参与核电厂维修任务或拆除地点的工人。如果发生反应堆事故,60Co将与其他放射性核素一起释放,一般民众也可能受到影响。接触稳定钴对健康的影响主要是呼吸和皮肤。然而,最近发现的某些钴化合物的致癌性需要警惕。除此之外,钴的放射性毒性尚未被探索。鉴于钴的多种用途和已查明的潜在暴露,为人类及其环境提供有效的保护手段至关重要。迄今为止,在吸入、摄入或皮肤损伤合并的情况下,目前的药理学治疗提供了完美的疗效。这篇综述文章概述了关于钴的最新知识状况,特别侧重于其生物动力学和毒理学数据,建议的医疗对策以及该领域的研究进展。最后,本综述提出了新的研究前景,特别是在医疗对策领域,这是辐射防护和职业健康方面最重要的领域。
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