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Risk Assessment for Workers with Wearable Medical Devices Exposed to Electromagnetic Fields. 佩戴可穿戴医疗设备的工人暴露于电磁场的风险评估。
IF 1 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 Epub Date: 2024-02-17 DOI: 10.1097/HP.0000000000001798
Cecilia Vivarelli, Federica Censi, Giovanni Calcagnini, Rosaria Falsaperla, Eugenio Mattei

Abstract: The exponential diffusion of wearable medical devices (WMD) in recent years has involved people of all ages, including workers. Workers who use WMDs should be considered at a particular risk from electromagnetic fields, and in accordance with EU Directive 2013/35/EU, they require an individual risk assessment. Currently, there is no international standard that provides specific guidance on how to perform such a risk assessment. This paper focuses on the effects of electromagnetic fields on WMDs and does not consider the direct effects on human body tissues. It aims to offer practical recommendations to employers and/or health physicists for the risk assessment of workers with WMDs. Focusing on EU countries, we first describe the requirements outlined by the technical standard for the electromagnetic compatibility (EMC) of medical electrical equipment EN 60601-1-2. Then, some general guidelines on how to perform the risk assessment are provided. The assessment can be conducted by comparing the field values measured in the workplace with the immunity test levels specified in the technical standards of medical electrical equipment. If the measured values are lower than the immunity test levels indicated in the standard and the distance from the electromagnetic source is greater than the distance used by the manufacturer during the EMC (electromagnetic compatibility) tests (typically 30 cm), the risk for the worker may be considered acceptable. However, if the measured values exceed the immunity test levels or the distance criteria, a specific evaluation based on a case-by-case analysis is required.

摘要:近年来,可穿戴医疗设备(WMD)呈指数级增长,涉及各个年龄段的人群,包括工人。使用 WMD 的工人应被视为具有电磁场的特殊风险,根据欧盟指令 2013/35/EU,他们需要进行个人风险评估。目前,还没有国际标准为如何进行此类风险评估提供具体指导。本文侧重于电磁场对大规模毁灭性武器的影响,而不考虑对人体组织的直接影响。本文旨在为雇主和/或健康物理学家提供实用建议,以便对使用大规模毁灭性武器的工人进行风险评估。以欧盟国家为重点,我们首先介绍了医疗电气设备电磁兼容性 (EMC) 技术标准 EN 60601-1-2 中列出的要求。然后,就如何进行风险评估提供一些一般性指导。可以通过比较工作场所测得的场值和医疗电气设备技术标准中规定的抗扰度测试水平来进行评估。如果测量值低于标准中规定的抗扰度测试水平,且与电磁源的距离大于制造商在 EMC(电磁兼容性)测试中使用的距离(通常为 30 厘米),则可以认为工人面临的风险是可以接受的。但是,如果测量值超过了抗扰度测试水平或距离标准,则需要根据具体情况进行具体分析。
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引用次数: 0
How Hermann J. Muller Viewed the Ernest Sternglass Contributions to Hereditary and Cancer Risk Assessment: Erratum. 赫尔曼-穆勒(Hermann J. Muller)如何看待欧内斯特-斯特恩格拉斯(Ernest Sternglass)对遗传和癌症风险评估的贡献:勘误。
IF 1 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 DOI: 10.1097/HP.0000000000001851
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引用次数: 0
HEALTH PHYSICS SOCIETY . 2024 AFFILIATE MEMBERS. 健康物理学会 .
IF 1 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 DOI: 10.1097/01.HP.0001025980.46535.34
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引用次数: 0
The Relationship Between Cancer and Radiation: A New Paradigm: Erratum. 癌症与辐射的关系:新范例:勘误。
IF 1 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 DOI: 10.1097/HP.0000000000001837
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引用次数: 0
Decommissioning of a Medical Cyclotron Vault: The Case Study of the National Cancer Institute of Milano. 医疗回旋加速器保险库的退役:米兰国家癌症研究所的案例研究。
IF 1 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 Epub Date: 2024-02-17 DOI: 10.1097/HP.0000000000001801
Andrea Pola, Davide Bortot, Stefano Pasquato, Davide Mazzucconi, Carlo Chiesa, Fabio Zanellati, Anna Brusa

Abstract: In the widespread use of medical cyclotrons for isotope production, radiological and economic consequences related to the decommissioning of particle accelerators are often neglected. However, decommissioning regulation and its related procedures always demand efforts and costs that can unexpectedly impact on budgets. The magnitude of this impact depends strongly on the residual radioactivity of the accelerator and of the vault, and more specifically on the kind and activity concentration of residual radionuclides. This work reports and discusses a case study that analyzes in detail the characterization activities needed for optimized management of the decommissioning of a medical cyclotron vault. In particular, this paper presents the activities carried out for assessing the activity concentrations and for guiding the disposal of the cyclotron vault of the Italian National Cancer Institute of Milano (INT). An unshielded 17 MeV cyclotron vault was characterized by high resolution gamma-ray spectrometry both in-situ and in-laboratory on extracted samples. Monte Carlo simulations were also carried out to assess the overall distribution of activation in the vault. After a few months from the final shutdown of the accelerator, activity concentrations in the concrete walls due to neutron activation exceeded the clearance levels in many regions, especially close to the cyclotron target. Due to the relatively long half-lives of some radionuclides, a time interval of about 20 y after the end of bombardment is necessary for achieving clearance in some critical positions. Far from the target or in positions shielded by the cyclotron, activation levels were below the clearance level. The comparison between Monte Carlo simulations and experimental results shows a good agreement. The in-situ measurements, simpler and economically advantageous, cannot completely replace the destructive measurements, but they may limit the number of required samples and consequently the decommissioning costs. The methodology described and the results obtained demonstrated that it is possible to obtain accurate estimations of activity concentrations with cheap and quick in-situ measurements if the concentration profile in-depth inside the wall is well known. This profile can be obtained either experimentally or numerically through suitably validated Monte Carlo simulations.

摘要:在广泛使用医用回旋加速器生产同位素的过程中,与粒子加速器退役有关的辐射和经济后果往往被忽视。然而,退役监管及其相关程序总是需要付出努力和成本,这可能会对预算产生意想不到的影响。这种影响的大小在很大程度上取决于加速器和拱顶的残余放射性,更具体地说,取决于残余放射性核素的种类和放射性浓度。这项工作报告和讨论了一个案例研究,详细分析了优化管理医用回旋加速器拱顶退役所需的特征描述活动。本文特别介绍了为评估放射性浓度和指导意大利米兰国家癌症研究所(INT)回旋加速器拱顶的处置而开展的活动。通过对提取的样品进行现场和实验室高分辨率伽马射线光谱分析,确定了无屏蔽 17 兆电子伏回旋加速器拱顶的特征。此外,还进行了蒙特卡罗模拟,以评估穹顶内活化的总体分布情况。加速器最终关闭几个月后,在许多区域,特别是靠近回旋加速器靶的区域,中子活化引起的混凝土墙内的放射性浓度超过了清除水平。由于某些放射性核素的半衰期相对较长,因此需要在轰击结束后间隔 20 年左右的时间才能在某些关键位置实现清除。在远离目标或被回旋加速器屏蔽的位置,活化水平低于清除水平。蒙特卡洛模拟与实验结果之间的比较显示出很好的一致性。原位测量比较简单,在经济上也有优势,但不能完全取代破坏性测量,但可以限制所需样品的数量,从而降低退役成本。所描述的方法和获得的结果表明,如果对深入墙内的浓度分布非常了解,就有可能通过廉价、快速的原位测量获得对放射性浓度的准确估计。这种分布可以通过实验获得,也可以通过经过适当验证的蒙特卡罗模拟以数值方式获得。
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引用次数: 0
Mechanical and Architectural Changes in Animal Bone Following Fast Neutron Irradiation. 快速中子辐照后动物骨骼的机械和结构变化
IF 1 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 Epub Date: 2024-03-15 DOI: 10.1097/HP.0000000000001811
Eduardo Galiano, Jinlu Liu, Beide Ren, Penghao Xu

Abstract: Damage to healthy bone following exposure to ionizing radiation has been well documented for at least seven decades. Among the reported effects are a transient increase in stiffness and a reduction in breaking strength. These changes have been linked to a decrease in osteoblast proliferation and differentiation, inducing cell cycle arrest, reducing collagen production, and increasing sensitivity to apoptotic agents. In this work, we analyzed some mechanical and structural changes in compact costal bovine bone (Hereford breed, n = 9) subjected to escalating doses of fast neutrons from a 7 Li(p,n) 7 Be reaction. The mean neutron energy was 233 keV with calculated absorbed doses ranging from 0 to 4.05 ± 10% Gy. Samples were subjected to Young's Modulus (YM) and breaking strength testing with a Universal Testing Machine (UTM). We found an increase in Young's Modulus and a decrease in breaking strength as functions of increasing dose equivalent. Optical coherence tomography (OCT) revealed trabecular displacement into compact bone in an irradiated sample (D = 4.05 ± 10% Gy), with breaching of the endosteal wall. OCT further revealed a "crack-like" structure across the irradiated sample, potentially consistent with damage from a proton track resulting from an elastic (n,p) reaction. No previous report has been found on mechanical changes in large mammalian bones following fast neutron doses, nor of the OCT imaging of such samples.

摘要:电离辐射对健康骨骼的损害至少已有七十年的记录。所报道的影响包括刚度的短暂增加和断裂强度的降低。这些变化与成骨细胞增殖和分化减少、细胞周期停滞、胶原蛋白生成减少以及对凋亡剂的敏感性增加有关。在这项研究中,我们分析了在7Li(p,n)7Be反应产生的快中子剂量不断增加的情况下,致密肋骨牛骨(Hereford 品种,n = 9)的一些机械和结构变化。平均中子能量为 233 keV,计算吸收剂量为 0 至 4.05 ± 10% Gy。用万能试验机(UTM)对样品进行了杨氏模量(YM)和断裂强度测试。我们发现,随着剂量当量的增加,杨氏模量增加,断裂强度降低。光学相干断层扫描(OCT)显示,在辐照样本(D = 4.05 ± 10% Gy)中,骨小梁移位到致密骨中,骨内壁被破坏。OCT 进一步显示,整个辐照样本出现了 "裂缝状 "结构,这可能与质子轨道造成的弹性(n,p)反应损伤一致。关于大型哺乳动物骨骼在受到快中子剂量照射后的机械变化,以及此类样本的 OCT 成像,目前还没有任何报道。
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引用次数: 0
HAZMAT Technician-level Emergency Response: A Mental Model Framework for Radiological Dispersal Device (RDD) Incidents. HAZMAT 技术员级应急响应:放射性扩散装置 (RDD) 事件的心理模型框架。
IF 1 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 Epub Date: 2024-05-26 DOI: 10.1097/HP.0000000000001809
Angela E Leek, Nir Keren, Daniel Blumenthal, William Irwin, Stephen Musolino

Abstract: This research examines the cognitive frameworks used by HAZMAT technicians when responding to incidents involving Radiological Dispersal Devices (RDDs), which are conventional explosive devices with radioactive materials incorporated. The objective is to introduce the Expected Mental Model State (EMMS) as a comprehensive evaluation tool for assessing and enhancing the expertise and situational awareness of emergency responders dealing with radiation crises. Through a series of expert focus group sessions using the well-established qualitative methodology of grounded theory, an Expected Mental Model State (EMMS) was developed. The methodology used an influence diagram architecture to conceptually capture and codify key areas relevant to effective emergency response. The research identifies fourteen EMMS key conceptual domains, further elaborated into 301 subtopics, providing a multi-dimensional structure for the proposed mental model framework. Three pivotal notions of mental model emerged within the EMMS framework: Knowledge Topology, Envisioning (Belief), and Response and Operability. These notions were found to align with previous theories of mental models and are vital for understanding how HAZMAT technicians conceptualize and respond to RDD incidents. The study emphasizes the critical role of mental models in enhancing preparedness and effective response strategies during radiation emergencies. The EMMS framework offers a versatile methodology that can be adapted across various kinds of emergency responders and high-risk situations, including the broader Chemical, Biological, Radiological, and Nuclear (CBRN) spectrum. Using this EMMS framework to develop an EMMS Diagnostic Matrix can provide a roadmap for identifying areas for the development of specialized training modules that have the potential to significantly elevate both the quality and efficacy of responder training and preparation.

摘要:本研究探讨了危险品、有害物质和有毒物质处理(HAZMAT)技术人员在应对涉及放射性扩散装置(RDD)的事件时所使用的认知框架。研究的目的是引入预期心理模型状态(EMMS),将其作为一种综合评估工具,用于评估和提高应急人员在处理辐射危机时的专业知识和态势感知能力。通过一系列专家焦点小组会议,利用成熟的基础理论定性方法,开发了预期心理模型状态(EMMS)。该方法采用影响图架构,从概念上捕捉并编纂与有效应急响应相关的关键领域。研究确定了 14 个 EMMS 关键概念领域,并进一步细化为 301 个子主题,为拟议的心智模式框架提供了一个多维结构。心智模式框架中出现了三个关键概念:知识拓扑结构、设想(信念)以及反应和可操作性。研究发现,这些概念与以往的心智模式理论相吻合,对于了解危险品、有害物质和有毒物质技术人员如何构思和应对 RDD 事件至关重要。这项研究强调了心智模式在加强辐射紧急情况下的准备工作和有效应对策略中的关键作用。EMMS 框架提供了一种通用方法,可适用于各种应急响应人员和高风险情况,包括更广泛的化学、生物、辐射和核(CBRN)领域。使用 EMMS 框架来开发 EMMS 诊断矩阵,可以为确定开发专门培训模块的领域提供路线图,这些模块有可能显著提高应急响应人员培训和准备工作的质量和效率。
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引用次数: 0
Theoretical Prediction of the 210 Pb Burden in the Skeleton from Radon Exposure and Other Intake Routes. 从氡暴露和其他摄入途径对骨骼中 210Pb 负担的理论预测。
IF 1 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-08-01 Epub Date: 2024-03-27 DOI: 10.1097/HP.0000000000001807
Jing Wang, Yuanyuan Liu, Bin Wu, Xiangpeng Meng, Yu Wang, Jianping Cheng

Abstract: The 210 Pb burden in the skeleton is a measurement value suitable for the estimation of the cumulative exposure to radon, based on which the resultant risk of lung cancer can be derived. There have been a handful of studies that successfully measured 210 Pb activity in the bones of volunteers who had chronic exposure to high concentrations of radon occupationally or in their residences. However, the quantitative relationship between measured 210 Pb activity and radon exposure remains elusive. Herein, we investigate the origin of the skeletal burden by employing the biokinetic model recommended by the International Commission on Radiological Protection and modeling various routes of intake. First, the baseline 210 Pb burden for the general public regarding eating assorted foodstuffs and breathing normal air is obtained. It is found that this baseline burden ranges between 7.3 to 46.5 Bq for a 50-y-old (male) person, which characterizes a large variance due to the uncertainty of each route of intake. Next, we concentrate on radon exposure by referring to two experimental studies where the accounts of exposure and the measured 210 Pb burden for each volunteer are documented in detail. From comparing our prediction and measurements, it is found that exposure to higher concentration of radon is the most significant source of 210 Pb intake, and the quantitative differences can be reasonably explained by the uncertainty resulting from regular intake routes. This study establishes the theoretical foundation for assessing one's risk of lung cancer due to radon exposure by measuring the 210 Pb burden in bones.

摘要:骨骼中的 210Pb 负荷是一个测量值,适用于估算氡的累积暴露量,并据此得出肺癌风险。已有少数研究成功测量了长期暴露于高浓度氡的职业或居住地志愿者骨骼中的 210Pb 活性。然而,所测得的 210Pb 活度与氡暴露之间的定量关系仍然难以捉摸。在此,我们采用国际辐射防护委员会推荐的生物动力学模型,并对各种摄入途径进行建模,从而研究骨骼负荷的来源。首先,我们获得了普通公众在食用各种食品和呼吸正常空气时的 210Pb 基准负荷。结果发现,一个 50 岁(男性)的人的基准负荷介于 7.3 至 46.5 Bq 之间,由于各种摄入途径的不确定性,差异很大。接下来,我们参考了两项实验研究,其中详细记录了每位志愿者的氡暴露情况和测得的 210Pb 负荷。通过比较我们的预测和测量结果,我们发现暴露于较高浓度的氡气是摄入 210Pb 的最主要来源,而数量上的差异可以通过常规摄入途径所产生的不确定性得到合理解释。这项研究为通过测量骨骼中的 210Pb 负荷来评估因暴露于氡气而罹患肺癌的风险奠定了理论基础。
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引用次数: 0
Conversion of Site-Specific Meteorological Data for use in CAP-88 PC. 将特定地点的气象数据转换用于 CAP-88 PC。
IF 1 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-07-25 DOI: 10.1097/HP.0000000000001857
B G Fritz, J A Peterson

Abstract: CAP-88 PC is a commonly used radiological atmospheric dispersion model. This US EPA-approved model is used to demonstrate compliance with atmospheric emission regulations for radionuclides. While the model includes a large library of meteorological data for use across the United States, there are applications when users may wish to use onsite meteorological data as an input to the CAP-88 PC model. Here we present a work-around process for preparing and converting onsite data for use in CAP-88 PC. However, the use of local data should provide a more realistic estimate of doses to members of the public in the immediate vicinity of a facility, although the regulatory agency having jurisdiction may not accept the use of local data for compliance. Additionally, the historical meteorological records from 20+ years ago (at a site many kilometers away) might not be representative of current local weather patterns, highlighting another benefit of using local meteorological data.

摘要:CAP-88 PC 是一种常用的放射性大气扩散模型。该模型经美国环保局批准,用于证明是否符合放射性核素大气排放法规。虽然该模型包含一个供全美使用的大型气象数据库,但在某些应用中,用户可能希望使用现场气象数据作为 CAP-88 PC 模型的输入。在此,我们将介绍一个准备和转换现场数据供 CAP-88 PC 使用的变通过程。不过,使用当地数据应能更真实地估算出设施附近公众所受的剂量,尽管具有管辖权的监管机构可能不接受使用当地数据来满足要求。此外,20 多年前的历史气象记录(在数公里之外的地点)可能并不代表当前的当地天气模式,这也凸显了使用当地气象数据的另一个好处。
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引用次数: 0
A Survey of Mean Glandular Doses and Suggestions on National Diagnostic Reference Levels for Digital Mammography in China. 中国数字乳腺 X 射线平均腺体剂量调查及国家诊断参考水平建议》。
IF 1 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-07-25 DOI: 10.1097/HP.0000000000001853
Hui Xu, Baorong Yue, Jinsheng Cheng, Jun Deng, Yinping Su, Qiaoqiao Zhao, Ke Xue, Zechen Feng, Yantao Niu, Quanfu Sun

Abstract: The primary purpose of this study was to report the mean glandular doses and to determine the national diagnostic reference levels for digital mammography based on data between 2016 and 2018 in China. The data from 19,076 mammograms (4,769 examinations) by random sampling from 118 digital mammography systems were compiled. Exposure factors included age, compressed breast thickness, kVp, mAs, target/filter combination, entrance surface air kerma, and mean glandular doses, which were retrospectively surveyed and recorded from the monitor. The national diagnostic reference levels (75th percentiles) in mean glandular dose were calculated across median value obtained for all included data and stratified to specific compressed breast thickness ranges. The patients' ages ranged from 22 to 88 y, with a median age of 45. The applied voltage and output medians were 28 kVp and 75.1 mAs for all exposure, respectively. The median CBTs were 45 mm and 48 mm for craniocaudal views and mediolateral oblique views, and the corresponding median mean glandular doses were 1.32 mGy and 1.40 mGy, respectively. The national diagnostic reference level at compressed breast thickness of 40-50 mm was 1.67 mGy for CC views and 1.71 mGy for MLO views. The median mean glandular doses varied significantly and increased with compressed breast thickness, demonstrating the necessity of establishing DRL according to breast thickness and optimizing the clinic's digital mammography practice in China.

摘要:本研究的主要目的是根据中国2016年至2018年的数据,报告平均腺体剂量并确定国家数字乳腺X光摄影诊断参考水平。研究汇编了从118套数字乳腺X光摄影系统中随机抽样的19076例乳腺X光检查(4769次检查)的数据。暴露因素包括年龄、压缩乳腺厚度、kVp、mAs、靶/滤光片组合、入口表面空气热玛和平均腺体剂量,这些因素都是通过监控器进行回顾性调查和记录的。平均腺体剂量的国家诊断参考水平(第 75 百分位数)是根据所有纳入数据的中位值计算得出的,并按照特定的压缩乳腺厚度范围进行了分层。患者年龄从 22 岁到 88 岁不等,中位年龄为 45 岁。所有暴露的应用电压和输出中值分别为 28 kVp 和 75.1 mAs。颅尾切面和内外侧斜切面的 CBT 中位数分别为 45 mm 和 48 mm,相应的平均腺体剂量中位数分别为 1.32 mGy 和 1.40 mGy。在压缩乳房厚度为 40-50 毫米时,CC 切面的国家诊断参考水平为 1.67 mGy,MLO 切面为 1.71 mGy。中位平均腺体剂量差异显著,并随压缩乳腺厚度的增加而增加,这表明根据乳腺厚度确定DRL并优化中国临床数字乳腺X光检查实践的必要性。
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引用次数: 0
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