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Risk Assessment for Nuclear Terrorism Probability and Its Application on a Hypothetical Nuclear Facility. 核恐怖主义概率风险评估及其在假想核设施中的应用。
IF 2.2 4区 医学 Q2 Medicine Pub Date : 2024-06-18 DOI: 10.1097/HP.0000000000001842
Joeun L Kot, Jason T Harris

Abstract: Radiation protection contains the key elements of nuclear safety and security. Despite the overlap between nuclear safety and security, their objectives differ fundamentally, focusing on unintentional accidents and intentional malicious events, respectively. As such, the Potential Facility Risk Index (PFRI), originally created for security purposes, has evolved into an approach that combines conventional probabilistic risk assessment (PRA), which is a widely employed method to evaluate the safety risks of nuclear facilities. This research has developed a risk assessment model within the PFRI framework to calculate the probability of nuclear terrorism. Three essential components of the model are integrated: an analysis of historical nuclear terrorism data to determine an initial threat frequency; the target-specific factor using analytical hierarchy process (AHP) target attractiveness analysis; and the adversary motivation factor based on site-specific social influences from the Profiles of Individual Radicalization in the United States (PIRUS) dataset. Applied to a hypothetical nuclear facility, the model produces a nuclear terrorism probability of 8.97 × 10-3 y - 1. The systematic methodology proposed in the study enables the derivation of nuclear terrorism probability with results in the same risk unit as safety risk assessment. This method allows decision makers to seamlessly incorporate nuclear safety and security risk assessments, offering a comprehensive perspective. Consequently, it enriches comprehension of nuclear facility risks and establishes the groundwork for future advancements.

摘要:辐射防护包含核安全与核安保的关键要素。尽管核安全与核安保之间存在重叠,但两者的目标却有本质区别,分别侧重于非蓄意事故和蓄意恶意事件。因此,最初为安保目的而创建的 "潜在设施风险指数"(PFRI)已发展成为一种结合了传统概率风险评估(PRA)的方法,这是一种广泛用于评估核设施安全风险的方法。这项研究在 PFRI 框架内开发了一个风险评估模型,用于计算核恐怖主义的概率。该模型集成了三个基本组成部分:分析历史核恐怖主义数据以确定初始威胁频率;使用分析层次过程(AHP)进行目标吸引力分析的特定目标因素;以及基于美国个人激进化概况(PIRUS)数据集的特定场所社会影响的对手动机因素。将该模型应用于假定的核设施,可得出核恐怖主义概率为 8.97 × 10-3 y - 1。研究中提出的系统方法可推导出核恐怖主义概率,其结果与安全风险评估的风险单位相同。这种方法允许决策者将核安全与核安保风险评估无缝结合,提供了一个全面的视角。因此,它丰富了对核设施风险的理解,并为未来的进步奠定了基础。
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引用次数: 0
Prediction Model for Defects in Lead and Lead-free Aprons. 铅和无铅围裙缺陷预测模型。
IF 2.2 4区 医学 Q2 Medicine Pub Date : 2024-06-17 DOI: 10.1097/HP.0000000000001847
Pieter-Jan Kellens, An De Hauwere, Sandrine Bayart, Klaus Bacher, Tom Loeys

Abstract: Personal radiation protective equipment (PRPE) is prone to defects in the attenuating layers, resulting in inadequate protection. Hence, quality control (QC) of PRPE is needed to assess its integrity. Unfortunately, QC of PRPE is laborious and time consuming. This study aimed to predict the QC outcome of PRPE without x-ray imaging based on readily available predictors. PRPE QC data of a general hospital from 2018 to 2023 was used for both prediction models based on logistic regression and random forests (RF). The data were divided into a training set containing all data from 2018 to 2022 and a holdout set containing the data from 2023. The predictors were brand, age, size, type, visual defects, and department. The prediction performances were compared using confusion matrices and visualized with receiver operating characteristic (ROC) curves. Prediction accuracies of at least 80% were achieved. Further model tuning especially improved the RF model to a precision up to 97% with a sensitivity of 80% and specificity of 86%. All predictors, except visual defects, significantly impacted the probability of passing. The predictor brand had the largest contribution to the predictive performance. The difference in pass probability between the best-performing and the worst-performing brand was 35.1%. The results highlight the potential of predicting PRPE QC outcome without x rays. The proposed prediction approach is a significant contribution to an effective QC strategy by reducing time consuming x-ray QC tests and focusing on garments with higher probability of being defective. Further research is recommended.

摘要:个人辐射防护设备(PRPE)的衰减层容易出现缺陷,导致防护效果不佳。因此,需要对 PRPE 进行质量控制 (QC),以评估其完整性。遗憾的是,PRPE 的质量控制费时费力。本研究旨在根据现成的预测指标,在没有 X 射线成像的情况下预测 PRPE 的质量控制结果。一家综合医院 2018 年至 2023 年的 PRPE QC 数据被用于基于逻辑回归和随机森林(RF)的预测模型。数据分为包含 2018 年至 2022 年所有数据的训练集和包含 2023 年数据的保留集。预测因子为品牌、年龄、大小、类型、视觉缺陷和科室。预测结果使用混淆矩阵进行比较,并通过接收器操作特征曲线(ROC)进行可视化。预测准确率至少达到了 80%。对模型的进一步调整尤其提高了 RF 模型的精确度,精确度高达 97%,灵敏度为 80%,特异度为 86%。除视觉缺陷外,所有预测因子都对通过概率有显著影响。预测因子品牌对预测性能的贡献最大。表现最好的品牌和表现最差的品牌之间的通过概率相差 35.1%。结果凸显了在没有 X 射线的情况下预测 PRPE 质量控制结果的潜力。所提出的预测方法减少了耗时的 X 射线质量控制测试,并将重点放在瑕疵概率较高的服装上,对有效的质量控制策略做出了重大贡献。建议进一步开展研究。
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引用次数: 0
Abstract 摘要
IF 2.2 4区 医学 Q2 Medicine Pub Date : 2024-06-01 DOI: 10.1097/hp.0000000000001806
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引用次数: 0
Protecting Our Own: A Method for Reducing Breast Radiation Exposure in Healthcare Workers. 保护我们自己:减少医护人员乳房辐射暴露的方法》(Protecting Our Own: A Method for Reducing Breast Radiation Exposure in Healthcare Workers)。
IF 2.2 4区 医学 Q2 Medicine Pub Date : 2024-05-06 DOI: 10.1097/HP.0000000000001832
Lauren Zammerilla Westcott, Gerald O Ogola, Chet R Rees

Abstract: Standard lead aprons do not protect the female breast adequately from radiation exposure, which has been associated with breast cancer in healthcare workers. A novel lead shield was designed to reduce radiation to the breast, axilla, and thyroid (BAT). A procedure room was simulated with an anthropomorphic phantom representing the operator. Dosimeters were positioned on the outer quadrant of each breast, the chest, the thyroid, and deep inside of a phantom acrylic female torso with neck and head. Standard lead vest plus a thyroid shield was used as control and compared to standard lead vest plus BAT shield. Three operator and two image receptor positions were tested. The reductions in radiation exposure were calculated. The standard vest plus BAT shield provided significant reductions in radiation exposure for all anatomic locations compared to control. When averaging all operator positions, the BAT provided reductions of 91% (p < 0.0001) for near breast. Reductions for far breast, chest, thyroid, and deep tissues were 76% (p = 0.016), 94% (p < 0.0001), 52% (p = 0.026), and 60% (p = 0.004). With operator 90° to the table using a cross-table lateral beam, the BAT provided a 97.7% reduction in radiation to the near breast and significant reduction in radiation to the chest, thyroid, and deep tissues. The BAT shield reduces radiation exposure to the breast, chest, thyroid and deep hematopoietic tissues. Such shields could benefit healthcare workers to reduce the risk of breast cancer and other radiation-associated cancers.

摘要:标准的铅围裙不能充分保护女性乳房免受辐射照射,而辐射照射与医护人员患乳腺癌有关。为了减少乳房、腋窝和甲状腺(BAT)的辐射,我们设计了一种新型铅防护罩。用一个代表操作者的拟人化模型模拟了一个手术室。剂量计被放置在每个乳房的外象限、胸部、甲状腺以及带有颈部和头部的丙烯酸女性躯干模型的内部深处。标准铅背心加甲状腺防护罩作为对照,并与标准铅背心加 BAT 防护罩进行比较。测试了三个操作员和两个图像接收器位置。计算了辐射照射的减少量。与对照组相比,标准背心加 BAT 防护罩可显著减少所有解剖位置的辐照量。如果对所有操作者位置进行平均,BAT 可使近乳房的辐射量减少 91%(p < 0.0001)。远乳房、胸部、甲状腺和深层组织的辐射量分别减少了 76% (p = 0.016)、94% (p < 0.0001)、52% (p = 0.026) 和 60% (p = 0.004)。操作者与手术台成 90°,使用跨台横向射束时,BAT 可将近处乳房的辐射减少 97.7%,并显著减少胸部、甲状腺和深部组织的辐射。BAT 防护罩可减少对乳房、胸部、甲状腺和深部造血组织的辐射照射。这种防护罩可以使医护人员受益,降低罹患乳腺癌和其他辐射相关癌症的风险。
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引用次数: 0
Neutron Activation Analysis Based on AB-BNCT Treatment Room. 基于 AB-BNCT 治疗室的中子活化分析。
IF 2.2 4区 医学 Q2 Medicine Pub Date : 2024-04-26 DOI: 10.1097/hp.0000000000001819
Yunzhu Cai, Shaoxian Gu, Ningyu Wang, Fengjie Cui, Wei Liu, Tianhang Li, Zhangwen Wu, Chengjun Gou
Boron neutron capture therapy (BNCT) is an ideal binary targeted radiotherapy for treating refractory tumors. An accelerator-based BNCT (AB-BNCT) neutron source has attracted more and more attention due to its advantages such as higher neutron yield in the keV energy region, less gamma radiation, and higher safety. In addition to 10B, neutrons also react with other elements in the treatment room during BNCT to produce many activation products. Due to the long half-life of some activation products, there will be residual radiation after the end of treatment and the shutdown of the accelerator, which has adverse effects on radiation workers. Therefore, the ambient dose equivalent rate in the treatment room needs to be evaluated. The AB-BNCT neutron source model proposed by Li is studied in this paper. Based on the Monte Carlo method, the Geant4 platform was used to simulate the dose induced by radionuclides near the Beam Shaping Assembly (BSA) of the source. It is concluded that the concrete wall contributed the most to the radiation dose. The dose rate of 2.45 μSv h-1 after 13 min of shutdown meets the dose rate limit of 2.5 μSv h-1, at which point it is safe for workers to enter the treatment room area.
硼中子俘获疗法(BNCT)是治疗难治性肿瘤的理想二元靶向放射疗法。基于加速器的硼中子俘获疗法(AB-BNCT)中子源因其在keV能量区具有较高的中子产率、较少的伽马辐射和较高的安全性等优点而受到越来越多的关注。除 10B 外,中子还会在 BNCT 期间与治疗室内的其他元素发生反应,产生许多活化产物。由于一些活化产物的半衰期较长,在治疗结束、加速器关闭后会有残余辐射,对辐射工作人员产生不利影响。因此,需要对治疗室的环境剂量当量率进行评估。本文研究了 Li 提出的 AB-BNCT 中子源模型。基于蒙特卡洛方法,利用 Geant4 平台模拟了放射源光束整形组件(BSA)附近放射性核素引起的剂量。结果表明,混凝土墙对辐射剂量的影响最大。关闭 13 分钟后的剂量率为 2.45 μSv h-1,符合剂量率限值 2.5 μSv h-1,此时工人进入治疗室区域是安全的。
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引用次数: 0
Consequences of Violating Conditions of Counting Statistics Are Not Severe When Measuring Radon Progeny Concentrations with the Thomas and Kusnetz Methods. 用托马斯法和库斯奈兹法测量氡子体浓度时,违反计数统计条件的后果并不严重。
IF 2.2 4区 医学 Q2 Medicine Pub Date : 2024-04-16 DOI: 10.1097/hp.0000000000001817
Phillip H Jenkins
When analyzing samples of radon progeny using the Thomas or Kusnetz methods, we violate one of the conditions of counting statistics because we use counting times that are not short compared with the half-lives of the radionuclides. The result is that we overestimate the uncertainties of the counts if we use counting statistics without correction. In this work, I describe the method by which I adjusted the values of variance of the counts theoretically to values that are more accurate and calculated the amounts by which I overestimate the values of counting uncertainty by using counting statistics without correction. These values are surprisingly small: 4-5% for the Thomas method and 2-3% for the Kusnetz method. Now, I can correct uncertainty values of radon progeny measurements if it is appropriate to do so. The detailed calculations I present here may be used for determining corrections to the counting uncertainty for a method for measuring radon progeny concentration using different sampling and/or counting times than those described here. Further, they may be used for any sample, not necessarily radon progeny, that requires a long counting time to acquire a significant number of observed counts.
在使用托马斯或库斯耐茨方法分析氡后代样本时,我们违反了计数统计的一个条件,因为我们使用的计数时间与放射性核素的半衰期相比并不短。结果就是,如果我们使用计数统计而不进行修正,我们就会高估计数的不确定性。在这项工作中,我介绍了将理论上的计数方差值调整为更精确值的方法,并计算了在使用计数统计而不进行校正的情况下高估计数不确定度的数值。这些数值小得出奇:托马斯方法为 4-5%,库斯涅茨方法为 2-3%。现在,我可以对氡后代测量的不确定度值进行修正,如果这样做是合适的。我在这里介绍的详细计算方法可用于确定对使用与这里所述不同的取样和/或计数时间测量氡原浓度的方法的计数不确定度的修正。此外,它们还可用于任何需要较长计数时间才能获得大量观测计数的样品,不一定是氡原。
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引用次数: 0
Why This Special Issue? 为什么要出版这期特刊?
IF 2.2 4区 医学 Q2 Medicine Pub Date : 2024-04-03 DOI: 10.1097/HP.0000000000001825
Mike Mahathy
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引用次数: 0
Science-informed Policy Making for Protecting People and the Environment from Radiation. 以科学为依据制定保护人类和环境免受辐射影响的政策。
IF 2.2 4区 医学 Q2 Medicine Pub Date : 2024-04-03 DOI: 10.1097/hp.0000000000001831
David Borrego, Jonathan S Nagata, Michael A Boyd, Sara D DeCair, Lauren R Matakas, Ellen W Wang, David J Pawel, Armin J Ansari
The process to arrive at the radiation protection practices of today to protect workers, patients, and the public, including sensitive populations, has been a long and deliberative one. This paper presents an overview of the US Environmental Protection Agency's (US EPA) responsibility in protecting human health and the environment from unnecessary exposure to radiation. The origins of this responsibility can be traced back to early efforts, a century ago, to protect workers from x rays and radium. The system of radiation protection we employ today is robust and informed by the latest scientific consensus. It has helped reduce or eliminate unnecessary exposures to workers, patients, and the public while enabling the safe and beneficial uses of radiation and radioactive material in diverse areas such as energy, medicine, research, and space exploration. Periodic reviews and analyses of research on health effects of radiation by scientific bodies such as the National Academy of Sciences, National Council on Radiation Protection and Measurements, United Nations Scientific Committee on the Effects of Atomic Radiation, and the International Commission on Radiological Protection continue to inform radiation protection practices while new scientific information is gathered. As a public health agency, US EPA is keenly interested in research findings that can better elucidate the effects of exposure to low doses and low dose rates of radiation as applicable to protection of diverse populations from various sources of exposure. Professional organizations such as the Health Physics Society can provide radiation protection practitioners with continuing education programs on the state of the science and describe the key underpinnings of the system of radiological protection. Such efforts will help equip and prepare radiation protection professionals to more effectively communicate radiation health information with their stakeholders.
为了保护工人、病人和公众(包括敏感人群),今天的辐射防护实践是一个漫长而慎重的过程。本文概述了美国环境保护局(US EPA)在保护人类健康和环境免受不必要的辐射照射方面的责任。这一责任的起源可以追溯到一个世纪前保护工人免受 X 射线和镭辐射的早期努力。今天,我们所采用的辐射防护系统是健全的,并以最新的科学共识为依据。它有助于减少或消除对工人、病人和公众的不必要照射,同时使辐射和放射性物质在能源、医学、研究和太空探索等不同领域得到安全有益的利用。美国国家科学院、国家辐射防护和测量委员会、联合国原子辐射影响问题科学委员会和国际辐射防护委员会等科学机构对辐射对健康影响的研究进行定期审查和分析,在收集新的科学信息的同时,继续为辐射防护实践提供信息。作为一个公共卫生机构,美国环保局对能够更好地阐明低剂量和低剂量率辐射照射的影响的研究成果非常感兴趣,这些研究成果适用于保护不同人群免受各种辐射源的照射。健康物理学会等专业组织可以为辐射防护从业人员提供有关科学现状的继续教育课程,并介绍辐射防护系统的关键基础。这些努力将帮助辐射防护专业人员做好准备,更有效地与利益相关者交流辐射健康信息。
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引用次数: 0
Society and Nuclear Energy: What Is the Role for Radiological Protection? 社会与核能:辐射防护的作用是什么?
IF 2.2 4区 医学 Q2 Medicine Pub Date : 2024-04-03 DOI: 10.1097/hp.0000000000001795
Wade Allison
The harm that society expects from ionizing radiation does not match experience. Evidently there is some basic error in this assumption. A reconsideration based on scientific principles shows how simple misunderstandings have exaggerated dangers. The consequences for society are far-reaching. The immediate impact of ionizing radiation on living tissue is destructive. However, this oxidative damage is similar to that produced during normal metabolic activity where the subsequent biological reaction is not only protective but also stimulates enhanced protection. This adaptation means that the response to oxidative damage depends on past experience. Similarly, social reaction to a radiological accident depends on the regulations and attitudes generated by the perception of previous instances. These shape whether nuclear technology and ionizing radiation are viewed as beneficial or as matters to avoid. Evidence of the spurious damage to society caused by such persistent fear in the second half of the 20th century suggests that these laws and attitudes should be rebased on evidence. The three stages of radiological impact-the initial physical damage, the subsequent biological response, and the personal and social reaction-call on quite different logic and understanding. When these are confused, they lead to regulations and public policy decisions that are often inept, dangerous, and expensive. One example is when the mathematical rigor of physics, appropriate to the immediate impact, is misapplied to the adaptive behavior of biology. Another, the tortured historical reputation of nuclear technology, is misinterpreted as justifying a radiological protection policy of extreme caution.Specialized education and closed groups of experts tend to lock in interdisciplinary misperceptions. In the case of nuclear technology, the resulting lack of independent political confidence endangers the adoption of nuclear power as the replacement for fossil fuels. In the long term, nuclear energy is the only viable source of large-scale primary energy, but this requires a re-working of public understanding.
社会对电离辐射危害的预期与实际情况不符。显然,这一假设存在一些基本错误。基于科学原理的重新考虑表明,简单的误解如何夸大了危险。电离辐射对社会的影响是深远的。电离辐射对活体组织的直接影响是破坏性的。然而,这种氧化损伤与正常新陈代谢活动中产生的氧化损伤相似,在正常新陈代谢活动中,随后的生物反应不仅具有保护作用,而且还能刺激加强保护。这种适应性意味着对氧化损伤的反应取决于过去的经验。同样,社会对放射性事故的反应也取决于对以往事件的认知所产生的法规和态度。这些因素决定了核技术和电离辐射是被视为有益的,还是被视为应该避免的。20 世纪下半叶,这种持续恐惧对社会造成的虚假损害的证据表明,这些法律和态度应该重新建立在证据的基础上。放射性影响的三个阶段--最初的物理损害、随后的生物反应以及个人和社会反应--需要完全不同的逻辑和理解。如果混淆了这三个阶段,就会导致制定的法规和公共政策决定往往是无能、危险和昂贵的。一个例子是,物理学的数学严谨性适用于直接影响,却被错误地应用于生物学的适应行为。另一个例子是,核技术饱受折磨的历史声誉被曲解为极端谨慎的辐射防护政策的正当理由。就核技术而言,由此导致的缺乏独立的政治信心危及到采用核能替代化石燃料。从长远来看,核能是唯一可行的大规模一次能源来源,但这需要公众重新认识核能。
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引用次数: 0
Protracted Exposure to a Sub-background Radiation Environment Negatively Impacts the Anhydrobiotic Recovery of Desiccated Yeast Sentinels. 长期暴露于亚背景辐射环境会对脱水酵母哨兵的无水生物恢复产生负面影响
IF 2.2 4区 医学 Q2 Medicine Pub Date : 2024-04-03 DOI: 10.1097/hp.0000000000001804
Michel R Lapointe, Taylor Laframboise, Jake Pirkkanen, T C Tai, Simon J Lees, Sergio R Santa Maria, Sujeenthar Tharmalingam, Douglas R Boreham, Christopher Thome
Experiments that examine the impacts of subnatural background radiation exposure provide a unique approach to studying the biological effects of low-dose radiation. These experiments often need to be conducted in deep underground laboratories in order to filter surface-level cosmic radiation. This presents some logistical challenges in experimental design and necessitates a model organism with minimal maintenance. As such, desiccated yeast (Saccharomyces cerevisiae) is an ideal model system for these investigations. This study aimed to determine the impact of prolonged sub-background radiation exposure in anhydrobiotic (desiccated) yeast at SNOLAB in Sudbury, Ontario, Canada. Two yeast strains were used: a normal wild type and an isogenic recombinational repair-deficient rad51 knockout strain (rad51Δ). Desiccated yeast samples were stored in the normal background surface control laboratory (68.0 nGy h-1) and in the sub-background environment within SNOLAB (10.1 nGy h-1) for up to 48 wk. Post-rehydration survival, growth rate, and metabolic activity were assessed at multiple time points. Survival in the sub-background environment was significantly reduced by a factor of 1.39 and 2.67 in the wild type and rad51∆ strains, respectively. Post-rehydration metabolic activity measured via alamarBlue reduction remained unchanged in the wild type strain but was 26% lower in the sub-background rad51∆ strain. These results demonstrate that removing natural background radiation negatively impacts the survival and metabolism of desiccated yeast, highlighting the potential importance of natural radiation exposure in maintaining homeostasis of living organisms.
研究亚天然本底辐射照射影响的实验为研究低剂量辐射的生物效应提供了一种独特的方法。这些实验通常需要在地下深处的实验室进行,以过滤地表水平的宇宙辐射。这给实验设计带来了一些后勤方面的挑战,而且需要一种维护成本最低的模式生物。因此,干燥酵母(Saccharomyces cerevisiae)是这些研究的理想模型系统。本研究旨在确定加拿大安大略省萨德伯里 SNOLAB 的无水生物(干燥)酵母受到长期次背景辐射照射的影响。研究使用了两种酵母菌株:正常野生型和同源重组修复缺陷rad51基因敲除菌株(rad51Δ)。干燥的酵母样品在正常背景表面控制实验室(68.0 nGy h-1)和 SNOLAB 内的次背景环境(10.1 nGy h-1)中保存长达 48 周。在多个时间点评估了补水后的存活率、生长率和代谢活动。野生型和 rad51∆ 菌株在亚背景环境中的存活率分别显著降低了 1.39 倍和 2.67 倍。通过茜草蓝还原法测量的补水后代谢活性在野生型菌株中保持不变,但在亚背景辐射 51∆ 菌株中则降低了 26%。这些结果表明,去除天然本底辐射会对干燥酵母的存活和新陈代谢产生负面影响,突出了天然辐射照射在维持生物体平衡方面的潜在重要性。
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