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Evaluating the Impact of Toolbox Training on Health Professionals in Radiation Environments: A Randomized Controlled Trial. 评估工具箱训练对辐射环境中卫生专业人员的影响:一项随机对照试验。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-03-01 Epub Date: 2026-01-28 DOI: 10.1097/HP.0000000000002101
Bircan Kara, Turan Şahmaran

In recent years, the use of radiation diagnostics, treatment services, and many areas of health services has become widespread with technological developments. The widespread use of radioactive substances and radiation-producing devices in health services has increased the need for effective radiation protection programs, and the need for training in terms of the applicability of these programs is also increasing. This randomized controlled trial was conducted to evaluate the effect of on-the-job toolbox training defined as a short, informal safety meeting led by a supervisor that focuses on specific workplace hazards or safe work practices on the knowledge, practices, and safety-related behaviors of healthcare professionals working in radiation environments. Sixty-three participants from the radiology units of a university hospital in Hatay, Türkiye, were randomly assigned to an intervention group (n=33) or a control group (n=30). The intervention group received brief, face-to-face training sessions using visual materials in their work environments. Data was collected before and after the training and at two follow-up periods. After the training, radiation protection knowledge increased significantly in the intervention group (p<0.001), while no change was observed in the control group. Observational assessments revealed that there was an improvement in practice scores in the intervention group and that the gains were largely maintained over time. Additionally, adverse event reporting, an important quality indicator, increased significantly in the intervention group, indicating increased safety awareness. These results confirm that toolbox training is an effective method for improving both knowledge and safe practices among healthcare professionals. Its brief, practical, and workplace-based format contributes to increased engagement and retention of learning. The findings support the integration of toolbox training into in-service training programs as a complement or alternative to traditional methods. Future studies should examine its long-term effectiveness and applicability in a variety of healthcare settings.

近年来,随着技术的发展,辐射诊断、治疗服务和许多卫生服务领域的使用已变得广泛。随着放射性物质和放射线装置在卫生服务中的广泛使用,对有效的辐射防护方案的需求日益增加,对这些方案适用性的培训需求也日益增加。本随机对照试验旨在评估在职工具箱培训的效果,该培训定义为由主管领导的短期非正式安全会议,重点介绍在辐射环境中工作的医疗保健专业人员的特定工作场所危害或安全工作实践的知识、实践和安全相关行为。来自基耶州哈塔伊市一所大学医院放射科的63名参与者被随机分配到干预组(n=33)或对照组(n=30)。干预组在他们的工作环境中使用视觉材料接受简短的面对面培训。在培训前后和两个随访期间收集数据。培训后,干预组患者的辐射防护知识显著增加(p
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引用次数: 0
Modeling and Evaluating the Effective Use of Sheltering-in-place for Protection against a Radiological Release during a Nuclear Power Plant Severe Accident. 核电厂严重事故中防护辐射释放的就地遮蔽物的有效使用建模与评估。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-03-01 Epub Date: 2026-01-28 DOI: 10.1097/HP.0000000000002057
Todd Smith, Steven Reese

Evacuation and sheltering-in-place are key protective actions during the early phase of a radiological emergency. Protective action strategies and decisions require balancing risks to ensure they provide more benefit than harm. While evacuations are generally safe, there are deterministic, long-term health consequences from prolonged displacement that outweigh the stochastic radiological health risk. In many cases, sheltering-in-place provides a viable alternative to evacuation, yet guidance and tools are lacking to aid decisionmakers on the best choice of action during an emergency caused by a nuclear power plant. Therefore, a method was developed to evaluate the effectiveness of sheltering-in-place and to explore ways to make better use of shelters during a radiological emergency. A model to estimate the radiological protection afforded by a typical residential shelter was developed and incorporated into a tool to examine the effectiveness of shelters during a hypothetical severe accident for typical BWR and PWR reactor designs and potential small modular reactor (SMR) design. The resultant analysis tool provides valuable insights into the parameters important to effective sheltering. Results demonstrate that typical residential homes can provide substantial dose reduction for an extended period of time following a significant radiological release. A sensitivity study was performed to identify important parameters and to inform how to implement sheltering-in-place for radiological emergencies involving different types of reactors and accidents with different radiological source terms. The model and results compared well to similar models and studies that also suggest shelters are more protective than previously understood. Additionally, contrary to the conventional shelter-in-place strategies, which recommend securing building ventilation, the results of this study suggest that sheltering strategies may benefit from a judicious operation of heating and ventilation systems for use in purifying indoor air to reduce inhalation dose.

在辐射紧急情况的早期阶段,疏散和就地避难是关键的防护行动。保护性行动战略和决策需要平衡风险,以确保利大于弊。虽然疏散总体上是安全的,但长期流离失所造成的确定的长期健康后果超过了随机放射健康风险。在许多情况下,就地避难提供了一种可行的疏散替代方案,但在核电站造成的紧急情况下,缺乏指导和工具来帮助决策者选择最佳行动。因此,制定了一种方法来评估就地掩体的有效性,并探讨如何在辐射紧急情况下更好地利用掩体。开发了一个估计典型住宅掩体所提供的辐射防护的模型,并将其纳入一个工具,以检验典型沸水堆和压水堆反应堆设计和潜在的小型模块化反应堆(SMR)设计在假设的严重事故期间掩体的有效性。由此产生的分析工具为有效遮蔽的重要参数提供了有价值的见解。结果表明,典型的住宅可以在重大放射释放后的较长时间内提供大量的剂量减少。进行了敏感性研究,以确定重要参数,并告知如何在涉及不同类型反应堆和具有不同放射源项的事故的放射性紧急情况下实施就地遮蔽。该模型和结果与类似的模型和研究进行了很好的比较,这些模型和研究也表明庇护所比以前所理解的更具保护性。此外,与传统的原地遮蔽策略(建议确保建筑物通风)相反,本研究的结果表明,在净化室内空气以减少吸入剂量时,明智地操作加热和通风系统可能有利于遮蔽策略。
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引用次数: 0
Uranium Concentration in Drinking Water and the Age-dependent Radiation Exposure in Chengalpattu District of Tamil Nadu, India. 印度泰米尔纳德邦Chengalpattu地区饮用水中的铀浓度和年龄相关的辐射暴露。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-03-01 Epub Date: 2025-07-07 DOI: 10.1097/HP.0000000000002015
S Palani, Satyanarayan Bramha, S Suja, S Chandrasekaran, A Vidyasakar, R Ravii Sankar

The current investigation involved collecting and analyzing groundwater samples from the Chengalpattu district in the state of Tamil Nadu. The content of uranium was determined using an LED fluorimeter. The uranium concentration exhibited a range of 0.02 μg L -1 to 2.814 μg L -1 , with a mean value of 0.347 μg L -1 and a standard deviation 3.05 μg L -1 . The uranium concentration levels calculated in this study are significantly below the recommended limits set by various agencies, including WHO (2011), US EPA (1991), ICRP (1995), UNSCEAR (1982), and AERB (2004), and these limits are used for critical in protecting public health. The annual ingestion dosage from uranium consumption via drinking water is estimated for all age groups and compared to the prescribed limits. The annual uranium intake in drinking water for various age groups ranges from 0.0224 μSv y -1 to 7.0674 μSv y -1 . The analysis shows that the doses are far below the recommended safety threshold. The average yearly intake dosage is well below the required threshold, indicating that the drinking water sources in the study region do not pose any harmful health risks related to uranium.

摘要:目前的调查包括在泰米尔纳德邦的Chengalpattu地区收集和分析地下水样本。铀的含量是用LED荧光计测定的。铀浓度范围为0.02 ~ 2.814 μ L-1,平均值为0.347 μ L-1,标准差为3.05 μ L-1。本研究计算的铀浓度水平大大低于各机构规定的建议限值,这些机构包括世卫组织(2011年)、美国环保署(1991年)、ICRP(1995年)、联合国科委会(1982年)和AERB(2004年),这些限值在保护公众健康方面至关重要。对所有年龄组通过饮用水消耗铀的年摄入剂量进行了估计,并与规定限值进行了比较。各年龄组饮用水中铀的年摄入量在0.0224 ~ 7.0674 μSv -1之间。分析表明,剂量远远低于建议的安全阈值。平均年摄入量远低于规定的阈值,表明研究区域的饮用水源不构成与铀有关的任何有害健康风险。
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引用次数: 0
Effective Dose Estimation with IDAC and OLINDA for 18 F-FDG and 68 Ga-PSMA PET/CT Procedures. 用IDAC和OLINDA估计18F-FDG和68Ga-PSMA PET/CT程序的有效剂量。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-03-01 Epub Date: 2025-08-29 DOI: 10.1097/HP.0000000000002034
Fatma Hilal Bikirli, Nesrin Altinsoy, Türkay Toklu

Internal dosimetry is a part of radiation safety for patients and radiation workers in nuclear medicine procedures. This study retrospectively determined the effective dose for oncology patients undergoing PET/CT scans by using widely used computer codes, and the results were compared with each other and literature. The study focused on the radiopharmaceuticals 18 F-FDG (n = 220) and 68 Ga-PSMA (n = 85), administered to 305 patients for cancer imaging at Yeditepe University Kosuyolu Hospital's nuclear medicine department. PET dose was calculated using OLINDA/EXM, IDAC-Dose 1.0 and IDAC-Dose 2.1 programs while ImPACT software was used to determine the effective dose from the CT scan. All effective doses were derived in accordance with ICRP 60 and ICRP 103 tissue weighting factors. PET effective doses from highest to lowest were calculated with OLINDA/EXM, IDAC-Dose 1.0, IDAC-Dose 2.1 (ICRP 60) and IDAC-Dose 2.1 (ICRP 103) as 9.96, 9.07, 7.01, 6.28 mSv respectively for 18 F-FDG. The highest PET effective dose was also calculated with OLINDA/EXM software as 3.65 mSv for 68 Ga-PSMA. For the total effective dose in PET/CT scans, CT contributed about 92% for 68 Ga-PSMA protocol and 75% for 18 F-FDG protocol.

摘要:内剂量测定是核医学过程中患者和放射工作人员辐射安全的重要组成部分。本研究采用广泛使用的计算机编码,回顾性确定肿瘤患者PET/CT扫描的有效剂量,并将结果与文献进行对比。该研究的重点是放射性药物18F-FDG (n = 220)和68Ga-PSMA (n = 85),在Yeditepe大学Kosuyolu医院核医学科对305名患者进行癌症成像。PET剂量采用OLINDA/EXM、IDAC-Dose 1.0和IDAC-Dose 2.1程序计算,CT扫描有效剂量采用ImPACT软件计算。所有有效剂量均根据ICRP 60和ICRP 103组织加权因子得出。采用OLINDA/EXM计算PET有效剂量,IDAC-Dose 1.0、IDAC-Dose 2.1 (ICRP 60)和IDAC-Dose 2.1 (ICRP 103)对18F-FDG的有效剂量从高到低分别为9.96、9.07、7.01、6.28 mSv。用OLINDA/EXM软件计算68Ga-PSMA的最高PET有效剂量为3.65 mSv。对于PET/CT扫描的总有效剂量,CT对68Ga-PSMA方案贡献约92%,对18F-FDG方案贡献约75%。关键词:有效剂量;内部剂量测定法;18 f-fdg;68 ga-psma;城/ EXM;IDAC剂量2.1;IDAC-Dose 1.0;PET / CT。
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引用次数: 0
Heating Rate Optimization for Enhanced Precision in Thermoluminescent Dosimetry. 提高热释光剂量测定精度的加热速率优化。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-03-01 Epub Date: 2025-08-12 DOI: 10.1097/HP.0000000000002017
Jordan D Noey, Joseph S Kopke, Kimberlee J Kearfott

This study investigates the impact of heating rates, ranging from 1 °C s- 1 to 20 °C s- 1 , on the precision of integrated peak counts determined using various thermoluminescent dosimeter materials. Lower heating rates influence precision due to prolonged integration of signal noise, while higher heating rates affect precision by pronounced thermal quenching effects. Using time-temperature profiles constructed with a linear heating ramp and a constant hold at maximum temperature, a range of heating rates was evaluated to identify an optimal condition that minimizes variance in integrated peak counts resulting from these effects. In addition, kinetic parameters of glow peaks were determined through peak deconvolution of each glow curve obtained and analyzed as a function of heating rate, with observed trends fit to appropriate models. These results were then compared to trapping parameters - namely the activation energy and frequency factor - independently extracted using the variable heating rate method to assess consistency across techniques. The results indicate that peak temperatures and intensities exhibit strong exponential dependence on heating rate, while activation energies and frequency factors show weak linear correlations. Trapping parameters obtained using the variable heating rate method fell within the range of values derived from peak deconvolution, supporting consistency between the two approaches. An optimal heating rate of 4 °C s- 1 was identified for minimizing variance in integrated peak counts across all dosimeter types tested. Both noise and thermal effects were shown to influence measurement variance, with thermal quenching effects having a more pronounced impact at higher heating rates. Additional factors affecting precision included dosimeter material, glow peak temperature, and overall glow curve complexity. These findings enhance the understanding of thermoluminescent dosimeter behavior and highlight the importance of optimizing the heating rate for improved measurement reliability.

摘要:本研究探讨了加热速率(从1°C s⁻1到20°C s⁻1)对使用各种热释光剂量计材料测定的综合峰数精度的影响。较低的加热速率由于信号噪声的长时间集成影响精度,而较高的加热速率由于明显的热淬火效应影响精度。利用线性加热坡道和最高温度下的恒定保持构造的时间-温度曲线,评估了一系列加热速率,以确定一个最佳条件,使这些影响导致的综合峰值计数方差最小化。此外,通过对获得的每条辉光曲线进行峰反褶积来确定辉光峰的动力学参数,并将其作为加热速率的函数进行分析,将观测到的趋势拟合到适当的模型中。然后将这些结果与捕获参数(即活化能和频率因子)进行比较,这些参数是使用可变加热速率方法独立提取的,以评估不同技术之间的一致性。结果表明,峰值温度和强度与升温速率呈指数相关,而活化能与频率因子呈弱线性相关。变升温速率法获得的捕获参数在峰值反褶积的范围内,支持了两种方法之间的一致性。4°C s的最佳加热速率被确定为最小限度地减少所有测试剂量计类型的综合峰值计数的差异。噪声和热效应都显示影响测量方差,热淬火效应在较高的加热速率下具有更明显的影响。影响精度的其他因素包括剂量计材料、辉光峰值温度和总体辉光曲线复杂性。这些发现增强了对热释光剂量计行为的理解,并强调了优化加热速率以提高测量可靠性的重要性。
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引用次数: 0
Development of a Physical Phantom for Occupational Eye Lens Dosimetry in a Non-homogeneous Radiation Field. 非均匀辐射场中职业性晶状体剂量测量物理模体的研制。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-03-01 Epub Date: 2025-08-29 DOI: 10.1097/HP.0000000000002030
Jeongin Kim, Seokon Kang, Yun-Mi Baek, Hyunjun Na, Seonghoon Cho, Seungjin Choi

Following the reduction in the occupational eye lens dose limit by the International Commission on Radiological Protection (ICRP), a physical phantom was developed to enable lens dose monitoring in complex radiation environments. The design is based on a validated eye model used to derive lens dose conversion coefficients. After evaluating various materials using Monte Carlo simulations, polymethyl methacrylate (PMMA) was selected for its ease of manufacturing and decontamination. The phantom's dose conversion coefficients were calculated for a range of photon energies and irradiation angles. Lens doses were measured using thermoluminescent dosimeter (TLD) chips embedded in the phantom and exposed to a 137 Cs reference field. Measurements were compared with simulation results, demonstrating good agreement. This newly developed PMMA phantom offers a practical solution for evaluating lens dose in non-uniform radiation fields such as those found in nuclear power plants.

摘要:随着国际放射防护委员会(ICRP)对职业性眼晶状体剂量限值的降低,开发了一种物理模体,用于复杂辐射环境下的晶状体剂量监测。该设计基于一个经过验证的眼睛模型,该模型用于推导晶状体剂量转换系数。在使用蒙特卡罗模拟评估各种材料后,选择了聚甲基丙烯酸甲酯(PMMA),因为它易于制造和净化。在一定的光子能量和照射角度范围内,计算了光体的剂量转换系数。透镜剂量测量使用热释光剂量计(TLD)芯片嵌入模体并暴露在137Cs参考场中。测量结果与仿真结果进行了比较,结果吻合较好。这种新开发的PMMA幻影为核电厂等非均匀辐射场中透镜剂量的评估提供了一种实用的解决方案。
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引用次数: 0
Improved Clearance Verification: Direct Application of Measurements' Distribution. 改进的间隙验证:测量分布的直接应用。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-03-01 Epub Date: 2026-01-28 DOI: 10.1097/HP.0000000000002098
Jonatan Jiselmark, Steven Adams, Robert A Meck

We have developed a method for calculating the probability of doses during clearance of land that makes no a priori assumptions about the statistical distribution of radionuclide measurements. Our method uses the actual distribution of survey and sampling measurements rather than assuming a specific distribution. It applies Monte Carlo simulations to the Sum of Fractions calculation and accounts for all known uncertainties. In addition, it defines the probability and uncertainty of complying with the clearance criterion. In contrast, nearly all demonstrations of compliance with clearance criteria currently are based on nonparametric statistics. As such, the analysis is for the median dose to an individual in the critical group. They are based on an assumed statistical distribution and do not account for all known uncertainties. In contrast, regulatory authorities base compliance on either the dose to representative person or the dose to the average member of the critical group - not the median member of the critical group. Accounting for uncertainties is required as noted in the assertion of at least eight international authorities, including the International Organization for Standardization and the International Union of Pure and Applied Chemistry. They state that a measurement without its stated uncertainties is incomplete, not technically sound, and may not be considered defensible. Our Monte Carlo Sum of Fractions method provides the highly accurate quantified probability and uncertainty of compliance with the clearance criterion because we simulate all the data with randomized uncertainties. Therefore, it improves verification of clearance. In this work we demonstrate the application of Monte Carlo Sum of Fractions method to measurement data from a real site as a "Proof of Concept" for clearance of land. The evaluation of the dose to either of the representative person or the mean dose, and quantified uncertainty due to known parameters are technically sound basis for demonstration of compliance with clearance criteria.

我们已经发展出一种计算清理土地期间剂量概率的方法,这种方法对放射性核素测量的统计分布不作任何先验假设。我们的方法使用调查和抽样测量的实际分布,而不是假设一个特定的分布。它将蒙特卡罗模拟应用于分数和计算,并考虑所有已知的不确定性。此外,还定义了符合间隙准则的概率和不确定性。相比之下,目前几乎所有符合清除标准的证明都是基于非参数统计。因此,分析是针对临界组中个体的中位剂量。它们基于假设的统计分布,不考虑所有已知的不确定性。相比之下,监管机构的依从性依据要么是对代表人物的剂量,要么是对临界组平均成员的剂量,而不是临界组中位数成员的剂量。至少有八个国际权威机构,包括国际标准化组织和国际纯粹与应用化学联合会的断言指出,需要考虑不确定性。他们指出,没有其规定的不确定度的测量是不完整的,在技术上不合理的,并且可能不被认为是站得住脚的。我们的蒙特卡罗分数和方法提供了高度精确的符合间隙标准的量化概率和不确定性,因为我们模拟了所有具有随机不确定性的数据。因此,它改善了间隙的验证。在这项工作中,我们展示了蒙特卡罗分数和方法在实际场地测量数据中的应用,作为土地清理的“概念证明”。对代表人员的剂量或平均剂量的评估,以及对已知参数的不确定性的量化,在技术上是证明符合清除标准的可靠依据。
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引用次数: 0
Skin Uptake of 131I in a Veterinary Practice. 兽医执业中131I的皮肤摄取。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-03-01 Epub Date: 2026-01-28 DOI: 10.1097/HP.0000000000002071
James P Abraham, Thomas E Johnson

Accidental trace 131I skin contamination resulted in an intake to a veterinary nuclear medicine technician at Colorado State University (CSU). The resulting dose to the technician was determined through an in-vivo measurement of radioactivity in the thyroid. Inhalation and ingestion of the isotope were ruled out due to the chemical nature of the 131I, as determined by a previous study. The CSU Radiation Control Office performed measurements of the technician's thyroid daily and then weekly to quantify the uptake [2.2 kBq (60.1 nCi)] as well as the effective half-life of 131I (7.61 days) for the technician. Establishing a technician-specific effective half-life by graphing in-vivo measurements also showed near agreement with established effective half-life determinations specified in ICRP 30 for inhalation. The university assessed the committed dose equivalent (CDE) to the thyroid using three different methods and assigned a the highest CDE calculated (4.1 mSv), and an SDE of 0.22 mSv from external contamination. The average of the CDE calculated via each method was 3.68 ± 0.38 mSv. A comparison of the 3 thyroid dose calculation methods resulted in a 10% coefficient of variation. Close agreement between the various calculations demonstrates that any of these methods would be sufficient in determining a committed effective dose to the thyroid, while providing a level of confidence to the technician that the determination is accurate and appropriate. A key aspect of this report is how even trace amounts of radioiodine on intact skin can result in measurable doses.

意外痕量131I皮肤污染导致科罗拉多州立大学(CSU)兽医核医学技术人员摄入。技术人员的剂量是通过体内甲状腺放射性测量来确定的。根据先前的一项研究,由于131I的化学性质,因此排除了吸入和摄入同位素的可能性。CSU辐射控制办公室每天和每周对技术员的甲状腺进行测量,以量化技术员的摄取[2.2 kBq (60.1 nCi)]以及131I的有效半衰期(7.61天)。通过绘制体内测量图来建立技术人员特有的有效半衰期,也显示出与ICRP 30中规定的吸入有效半衰期测定方法接近一致。该大学使用三种不同的方法评估了甲状腺的承诺剂量当量(CDE),并指定了计算出的最高CDE(4.1毫西弗)和外部污染的SDE 0.22毫西弗。各方法计算的CDE平均值为3.68±0.38 mSv。对3种甲状腺剂量计算方法进行比较,变异系数为10%。各种计算之间的密切一致表明,这些方法中的任何一种都足以确定对甲状腺的承诺有效剂量,同时为技术人员提供了确定准确和适当的信心。本报告的一个关键方面是,即使是在完整皮肤上的微量放射性碘也会产生可测量的剂量。
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引用次数: 0
Retrospective Reconstruction of Biological Dose in Early Radiation Accident Cases Through Chromosomal Translocations Analysis Using G-Banding. 用g带染色体易位分析早期放射事故病例的生物剂量回顾性重建。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-03-01 Epub Date: 2026-01-28 DOI: 10.1097/HP.0000000000002096
Yu Gao, Ping Wang, Jie Li, Lin Han, Fengling Zhao, Qiang Liu, Yumin Lyu

Objective: To analyze stable chromosomal aberrations and reconstruct the biological dose in 6 victims of the Henan "4.26" 60Co radiation accident, 9 and 20 years after irradiation.

Methods: G-banding chromosomal specimens were prepared using conventional culture and trypsin digestion methods. Stable chromosomal aberrations in six victims were analyzed with an automated chromosome scanning system and karyotype analysis software to estimate the biological dose based on chromosomal translocation indicators.

Results: The number of stable chromosomal aberrations per cell at the two follow-ups demonstrated a significant dose-effect relationship with the radiation dose. A noticeable increase in translocations per cell was observed 20 years after the accident compared with 9 years. At 9 years post-irradiation, the mean absorbed doses for four cases, estimated from translocations per cell, were similar to those estimated from dicentrics plus rings at 5 days post-irradiation, while a slight decrease was observed in one case. At 20 years post-irradiation, the mean absorbed dose based on translocations per cell for five cases was essentially the same as the dose estimated from dicentrics plus rings at 5 days post-irradiation.

Conclusion: The G-banding approach, characterized by its simplicity and low cost, is feasible for analyzing chromosomal translocations and retrospectively reconstructing the biological dose of early radiation accidents.

目的:分析河南“4.26”60Co辐射事故6名受伤者在照射后9年和20年的稳定染色体畸变并重建其生物剂量。方法:采用常规培养法和胰蛋白酶消化法制备g带染色体标本。采用染色体自动扫描系统和核型分析软件对6例患者的稳定染色体畸变进行分析,根据染色体易位指标估算生物剂量。结果:在两次随访中,每个细胞的稳定染色体畸变数与辐射剂量呈显著的剂量效应关系。与事故发生后9年相比,事故发生后20年每个细胞的易位明显增加。在辐照后9年,根据每个细胞易位估计的4例患者的平均吸收剂量与辐照后5天通过双中心加环估计的剂量相似,而在1例患者中观察到略有下降。在辐照后20年,5例病例中基于每个细胞易位的平均吸收剂量与辐照后5天由双心正环估计的剂量基本相同。结论:g带法简便、成本低,是早期放射事故染色体易位分析和生物剂量回顾性重建的可行方法。
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引用次数: 0
Medical Radiation Exposures in Canada: 2017. 加拿大医疗辐射暴露:2017。
IF 1.4 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2026-02-06 DOI: 10.1097/HP.0000000000002091
Julie J Burtt, Seshan Anandarajah, Andra Morrison, Ruth C Wilkins

Radiation-based medical techniques and devices provide significant benefits to patients through the diagnosis, treatment, and management of illness and disease. Documenting trends and frequency of use offer important insights into radiation protection and help address gaps in the documentation of medical exposures. Here, we present the retrospective Canadian data collected for the recent United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) global survey on medical exposure. The global survey included three modality categories: diagnostic and interventional radiology, nuclear medicine, and radiotherapy and reports the total number of devices, physicians, examinations, and procedures. Due to the inability to collect high-quality dose data from Canadian sources, the average doses for specific examinations and treatments were estimated using internationally pooled data. The total annual per capita dose from medical exposures was determined to be 1.56 mSv, excluding radiotherapy, resulting in approximately 47% of all radiation doses received by Canadians, compared to natural, industrial, and consumer product sources. This assessment of Canadian medical radiation exposures contributes to global improvement of patient protection, helps establish trends, and identifies where Canadian data collection is lacking, particularly dose data.

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Health physics
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