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ADIPOGENESIS FEATURES OF WHITE, BEIGE AND BROWN ADIPOSE TISSUES 白色、米色和棕色脂肪组织的脂肪形成特征
Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-358-359
E. Kotenkova
White and brown adipose tissue is present in the human body and is well described. As well as the effect of the type of fat on human health, in particular obesity, type 2 diabetes, insulin tolerance. The presence and distribution of different types of fat in pigs has not been adequately described. As well as the factors contributing to the "browning" of white fat and the ability to influence this process in pigs.
白色和棕色脂肪组织存在于人体中,并被很好地描述。以及脂肪类型对人体健康的影响,特别是肥胖症、2型糖尿病、胰岛素耐受性。猪体内不同类型脂肪的存在和分布尚未得到充分的描述。以及导致猪白色脂肪“褐变”的因素和影响这一过程的能力。
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引用次数: 0
MODIFICATION OF THE SOLID-PHASE METHOD FOR THE SYNTHESIS OF MEDICAL DIOPSIDE FROM MATERIALS OF BIOLOGICAL ORIGIN 生物源材料固相法合成药用透辉苷的改进
Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-35-36
F. Senatov, R. Choudhary, E. Kolesnikov
A modified method for synthesis of diopside for biological applications from biowaste was developed.
研究了一种以生物废弃物为原料合成薯蓣皂苷的改进方法。
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引用次数: 0
WAYS TO IMPROVE THE TRADITIONAL COCARBOXYLASE SORPTION PURIFICATION TECHNOLOGY 改进传统的辅羧化酶吸附纯化工艺
Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-189-191
N. Kotova, A.V. Kovaneva, S.V. Kholodaeva, T.A. Pyatiizbyantsev
This work presents the results of experiments of cocarboxylase sorption from a model solution on sorbents of various structures under static and dynamic conditions. The sorbent was selected for the development of a sorption-chromatographic method for the isolation of cocarboxylase from a mixture of thiamine esters.
本文介绍了在静态和动态条件下,不同结构的吸附剂在模型溶液中吸附辅羧化酶的实验结果。选择该吸附剂用于开发从硫胺素酯混合物中分离辅酶羧化酶的吸附-色谱方法。
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引用次数: 0
APPLICATION OF AMBR15 MINIBIOREACTORS IN CHARACTERIZATION OF SUSPENSION MONOCLONAL ANTIBODY CHO-PRODUCER CELL CULTURE PROCESS BASED ON QBD PRINCIPLES 基于QBD原理的ambr15微型反应器在悬浮单克隆抗体产生细胞培养过程中的应用
Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-180-181
A. N. Morozov, I. R. Yakhin
A systematic approach to characterizing the cell culture process of CHO-producers of monoclonal antibodies within the framework of the concept "Quality by design" (QbD) with the use of ambr15 mini-bioreactors (TAP Biosystems) is shown.
在“质量设计”(QbD)的概念框架内,使用ambr15微型生物反应器(TAP Biosystems),系统地描述了单克隆抗体cho生产者的细胞培养过程。
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引用次数: 0
VISUAL STIMULATION CHANGES THE RATIO OF CONCENTRATIONS OF PARTICIPANTS OF THE GLUTAMINE-GLUTAMATE CYCLE IN THE ACTIVATED HUMAN CEREBRAL CORTEX 视觉刺激改变了被激活的人类大脑皮层中谷氨酰胺-谷氨酸循环参与者的浓度比例
Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-116-117
N. Semenova, A. Yakovlev, M. V. Ublinsky, T. Akhadov
A significant increase in the concentrations of Glu and Gln was found. Gln growth characterizes the activation of the Glu-Gln cycle in the visual cortex under constant stimulation. The increase in Glu in response to exercise is most likely caused by the activation of its synthesis.
谷氨酸和谷氨酰胺的浓度显著升高。在持续的刺激下,Gln的生长表现为视觉皮层中Gln -Gln循环的激活。运动后Glu的增加很可能是由其合成的激活引起的。
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引用次数: 0
ANALYTICAL SYSTEMS BASED ON RECOMBINASE POLYMERASE AMPLIFICATION FOR RAPID DETECTION OF VIRAL, VIROID AND BACTERIAL PLANT PATHOGENS 基于重组酶聚合酶扩增的快速检测病毒、类病毒和细菌植物病原体的分析系统
Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-242-244
A. Ivanov, A. Zherdev, B. Dzantiev
Test systems have been developed for the detection of phytopathogens, combining recombinase polymerase amplification and membrane test strips. Test systems provide detection of potato virus X, potato spindle tuber viroid, potato blackleg pathogen (Dickeya solani), as well as multi-analysis of three viruses. Amplification is carried out at 37 °C. The analysis time does n ot exceed 30 min.
结合重组酶聚合酶扩增和膜试纸,开发了植物病原体检测系统。检测系统可检测马铃薯X病毒、马铃薯梭形块茎类病毒、马铃薯黑腿病菌(Dickeya solani),以及三种病毒的多重分析。在37℃下进行扩增。分析时间不超过30分钟。
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引用次数: 0
THERMOHELIOX INFLUENCE ON THE PROTEOMIC COMPOSITION OF EXHALED BREATH CONDENSATE 热日光对呼出冷凝物蛋白质组学组成的影响
Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-119-121
L. V. Shogenova, A. Kononikhin, A. Kozyr, A. Panin, S. D. Varfolomeev, A. Chuchalin
The proteome of exhaled breath condensate was analyzed by mass spectrometry before, immediately after the thermoheliox procedure and after a 3 h relaxation. The major part of the proteome remained unchanged and there was no extensive cell destruction
用质谱法分析呼出气体凝析液的蛋白质组,并在热heliox程序之前、之后立即进行分析。蛋白质组的主要部分保持不变,没有广泛的细胞破坏
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引用次数: 0
DEOXYURIDINE TRIPHOSPHATES MODIFIED WITH AROMATIC GROUPS OF TYROSINE OR TRYPTOPHAN FOR DIRECT ELECTROCHEMICAL DETERMINATION OF DOUBLE-STRANDED DNA AMPLIFICATION PRODUCTS 用酪氨酸或色氨酸芳香基团修饰的三磷酸脱氧尿嘧啶直接电化学测定双链DNA扩增产物
Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-248-250
S. Khmeleva, G. Kutdusova, I. F. Duskaev, K. Ptitsyn, V. E. Kuznetsova, S. Lapa, A. V. Chudinov, S. Radko
A set of deoxyuridine triphosphates modified with aromatic groups of tyrosine or tryptophan was studied as substrates for amplification (by polymerase chain reaction or recombinase polymerase amplification) and as carriers of an electroactive ‘label’ for direct electrochemical detection of double-stranded DNA.
研究了一组由酪氨酸或色氨酸芳香基团修饰的脱氧尿苷三磷酸作为扩增底物(通过聚合酶链反应或重组酶聚合酶扩增)和作为直接电化学检测双链DNA的电活性“标签”载体。
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引用次数: 0
QUANTUM CHEMICAL ARTIFICIAL NEURAL NETWORK QSAR-MODELLING FOR ANTIGLYCATION ACTIVITY PREDICTION 用于抗糖化活性预测的量子化学人工神经网络qsar建模
Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-201-202
P.M. Vasilev, U.M. Ibragimova, A. Rzaeva
As a result of work to create the optimal quantum-chemical neural network model for antiglycation activity prediction, a set of different neural network models was received.
为了建立用于抗糖化活性预测的最佳量子化学神经网络模型,我们得到了一组不同的神经网络模型。
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引用次数: 0
BIOCONVERSION OF PLANT RAW MATERIALS INTO ETHANOL AND FEED PRODUCTS IN A CLOSED CYCLE 在一个封闭的循环中将植物原料转化为乙醇和饲料产品
Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-324-326
I. Abramova, М.V. Turshatov, V. Krivchenko, V. D. Nikitenko
In the process of bioconversion of grain raw materials into ethyl alcohol and protein feedstuffs, liquid effluents are formed. There is a possibility of effluent using in the treatment process in a closed cycle. The article presents the results of studies on the use of stillage filtrate and acidic condensate and their effect on yeast metabolism.
粮食原料在生物转化为乙醇和蛋白质饲料的过程中,会形成液体流出物。在处理过程中,废水有可能在封闭循环中使用。本文介绍了使用蒸馏滤液和酸性冷凝液及其对酵母代谢影响的研究结果。
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引用次数: 0
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