Pub Date : 2021-01-01DOI: 10.37747/2312-640x-2021-19-358-359
E. Kotenkova
White and brown adipose tissue is present in the human body and is well described. As well as the effect of the type of fat on human health, in particular obesity, type 2 diabetes, insulin tolerance. The presence and distribution of different types of fat in pigs has not been adequately described. As well as the factors contributing to the "browning" of white fat and the ability to influence this process in pigs.
{"title":"ADIPOGENESIS FEATURES OF WHITE, BEIGE AND BROWN ADIPOSE TISSUES","authors":"E. Kotenkova","doi":"10.37747/2312-640x-2021-19-358-359","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-358-359","url":null,"abstract":"White and brown adipose tissue is present in the human body and is well described. As well as the effect of the type of fat on human health, in particular obesity, type 2 diabetes, insulin tolerance. The presence and distribution of different types of fat in pigs has not been adequately described. As well as the factors contributing to the \"browning\" of white fat and the ability to influence this process in pigs.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91040897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.37747/2312-640x-2021-19-35-36
F. Senatov, R. Choudhary, E. Kolesnikov
A modified method for synthesis of diopside for biological applications from biowaste was developed.
研究了一种以生物废弃物为原料合成薯蓣皂苷的改进方法。
{"title":"MODIFICATION OF THE SOLID-PHASE METHOD FOR THE SYNTHESIS OF MEDICAL DIOPSIDE FROM MATERIALS OF BIOLOGICAL ORIGIN","authors":"F. Senatov, R. Choudhary, E. Kolesnikov","doi":"10.37747/2312-640x-2021-19-35-36","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-35-36","url":null,"abstract":"A modified method for synthesis of diopside for biological applications from biowaste was developed.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78234433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.37747/2312-640x-2021-19-189-191
N. Kotova, A.V. Kovaneva, S.V. Kholodaeva, T.A. Pyatiizbyantsev
This work presents the results of experiments of cocarboxylase sorption from a model solution on sorbents of various structures under static and dynamic conditions. The sorbent was selected for the development of a sorption-chromatographic method for the isolation of cocarboxylase from a mixture of thiamine esters.
{"title":"WAYS TO IMPROVE THE TRADITIONAL COCARBOXYLASE SORPTION PURIFICATION TECHNOLOGY","authors":"N. Kotova, A.V. Kovaneva, S.V. Kholodaeva, T.A. Pyatiizbyantsev","doi":"10.37747/2312-640x-2021-19-189-191","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-189-191","url":null,"abstract":"This work presents the results of experiments of cocarboxylase sorption from a model solution on sorbents of various structures under static and dynamic conditions. The sorbent was selected for the development of a sorption-chromatographic method for the isolation of cocarboxylase from a mixture of thiamine esters.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78239189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.37747/2312-640x-2021-19-180-181
A. N. Morozov, I. R. Yakhin
A systematic approach to characterizing the cell culture process of CHO-producers of monoclonal antibodies within the framework of the concept "Quality by design" (QbD) with the use of ambr15 mini-bioreactors (TAP Biosystems) is shown.
{"title":"APPLICATION OF AMBR15 MINIBIOREACTORS IN CHARACTERIZATION OF SUSPENSION MONOCLONAL ANTIBODY CHO-PRODUCER CELL CULTURE PROCESS BASED ON QBD PRINCIPLES","authors":"A. N. Morozov, I. R. Yakhin","doi":"10.37747/2312-640x-2021-19-180-181","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-180-181","url":null,"abstract":"A systematic approach to characterizing the cell culture process of CHO-producers of monoclonal antibodies within the framework of the concept \"Quality by design\" (QbD) with the use of ambr15 mini-bioreactors (TAP Biosystems) is shown.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85654701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.37747/2312-640x-2021-19-116-117
N. Semenova, A. Yakovlev, M. V. Ublinsky, T. Akhadov
A significant increase in the concentrations of Glu and Gln was found. Gln growth characterizes the activation of the Glu-Gln cycle in the visual cortex under constant stimulation. The increase in Glu in response to exercise is most likely caused by the activation of its synthesis.
{"title":"VISUAL STIMULATION CHANGES THE RATIO OF CONCENTRATIONS OF PARTICIPANTS OF THE GLUTAMINE-GLUTAMATE CYCLE IN THE ACTIVATED HUMAN CEREBRAL CORTEX","authors":"N. Semenova, A. Yakovlev, M. V. Ublinsky, T. Akhadov","doi":"10.37747/2312-640x-2021-19-116-117","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-116-117","url":null,"abstract":"A significant increase in the concentrations of Glu and Gln was found. Gln growth characterizes the activation of the Glu-Gln cycle in the visual cortex under constant stimulation. The increase in Glu in response to exercise is most likely caused by the activation of its synthesis.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85730331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.37747/2312-640x-2021-19-242-244
A. Ivanov, A. Zherdev, B. Dzantiev
Test systems have been developed for the detection of phytopathogens, combining recombinase polymerase amplification and membrane test strips. Test systems provide detection of potato virus X, potato spindle tuber viroid, potato blackleg pathogen (Dickeya solani), as well as multi-analysis of three viruses. Amplification is carried out at 37 °C. The analysis time does n ot exceed 30 min.
{"title":"ANALYTICAL SYSTEMS BASED ON RECOMBINASE POLYMERASE AMPLIFICATION FOR RAPID DETECTION OF VIRAL, VIROID AND BACTERIAL PLANT PATHOGENS","authors":"A. Ivanov, A. Zherdev, B. Dzantiev","doi":"10.37747/2312-640x-2021-19-242-244","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-242-244","url":null,"abstract":"Test systems have been developed for the detection of phytopathogens, combining recombinase polymerase amplification and membrane test strips. Test systems provide detection of potato virus X, potato spindle tuber viroid, potato blackleg pathogen (Dickeya solani), as well as multi-analysis of three viruses. Amplification is carried out at 37 °C. The analysis time does n ot exceed 30 min.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88215452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.37747/2312-640x-2021-19-119-121
L. V. Shogenova, A. Kononikhin, A. Kozyr, A. Panin, S. D. Varfolomeev, A. Chuchalin
The proteome of exhaled breath condensate was analyzed by mass spectrometry before, immediately after the thermoheliox procedure and after a 3 h relaxation. The major part of the proteome remained unchanged and there was no extensive cell destruction
{"title":"THERMOHELIOX INFLUENCE ON THE PROTEOMIC COMPOSITION OF EXHALED BREATH CONDENSATE","authors":"L. V. Shogenova, A. Kononikhin, A. Kozyr, A. Panin, S. D. Varfolomeev, A. Chuchalin","doi":"10.37747/2312-640x-2021-19-119-121","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-119-121","url":null,"abstract":"The proteome of exhaled breath condensate was analyzed by mass spectrometry before, immediately after the thermoheliox procedure and after a 3 h relaxation. The major part of the proteome remained unchanged and there was no extensive cell destruction","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82531141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.37747/2312-640x-2021-19-248-250
S. Khmeleva, G. Kutdusova, I. F. Duskaev, K. Ptitsyn, V. E. Kuznetsova, S. Lapa, A. V. Chudinov, S. Radko
A set of deoxyuridine triphosphates modified with aromatic groups of tyrosine or tryptophan was studied as substrates for amplification (by polymerase chain reaction or recombinase polymerase amplification) and as carriers of an electroactive ‘label’ for direct electrochemical detection of double-stranded DNA.
{"title":"DEOXYURIDINE TRIPHOSPHATES MODIFIED WITH AROMATIC GROUPS OF TYROSINE OR TRYPTOPHAN FOR DIRECT ELECTROCHEMICAL DETERMINATION OF DOUBLE-STRANDED DNA AMPLIFICATION PRODUCTS","authors":"S. Khmeleva, G. Kutdusova, I. F. Duskaev, K. Ptitsyn, V. E. Kuznetsova, S. Lapa, A. V. Chudinov, S. Radko","doi":"10.37747/2312-640x-2021-19-248-250","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-248-250","url":null,"abstract":"A set of deoxyuridine triphosphates modified with aromatic groups of tyrosine or tryptophan was studied as substrates for amplification (by polymerase chain reaction or recombinase polymerase amplification) and as carriers of an electroactive ‘label’ for direct electrochemical detection of double-stranded DNA.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85271949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.37747/2312-640x-2021-19-201-202
P.M. Vasilev, U.M. Ibragimova, A. Rzaeva
As a result of work to create the optimal quantum-chemical neural network model for antiglycation activity prediction, a set of different neural network models was received.
为了建立用于抗糖化活性预测的最佳量子化学神经网络模型，我们得到了一组不同的神经网络模型。
{"title":"QUANTUM CHEMICAL ARTIFICIAL NEURAL NETWORK QSAR-MODELLING FOR ANTIGLYCATION ACTIVITY PREDICTION","authors":"P.M. Vasilev, U.M. Ibragimova, A. Rzaeva","doi":"10.37747/2312-640x-2021-19-201-202","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-201-202","url":null,"abstract":"As a result of work to create the optimal quantum-chemical neural network model for antiglycation activity prediction, a set of different neural network models was received.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79822413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.37747/2312-640x-2021-19-324-326
I. Abramova, М.V. Turshatov, V. Krivchenko, V. D. Nikitenko
In the process of bioconversion of grain raw materials into ethyl alcohol and protein feedstuffs, liquid effluents are formed. There is a possibility of effluent using in the treatment process in a closed cycle. The article presents the results of studies on the use of stillage filtrate and acidic condensate and their effect on yeast metabolism.
{"title":"BIOCONVERSION OF PLANT RAW MATERIALS INTO ETHANOL AND FEED PRODUCTS IN A CLOSED CYCLE","authors":"I. Abramova, М.V. Turshatov, V. Krivchenko, V. D. Nikitenko","doi":"10.37747/2312-640x-2021-19-324-326","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-324-326","url":null,"abstract":"In the process of bioconversion of grain raw materials into ethyl alcohol and protein feedstuffs, liquid effluents are formed. There is a possibility of effluent using in the treatment process in a closed cycle. The article presents the results of studies on the use of stillage filtrate and acidic condensate and their effect on yeast metabolism.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83502197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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