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Neuroleptic malignant syndrome after abrupt discontinuation of neuroleptic and anticholinergic drugs 神经安定剂和抗胆碱能药物突然停药后的神经安定剂恶性综合征
Pub Date : 2023-11-01 DOI: 10.4103/ipj.ipj_207_23
Sameer Bhargava, Khushboo Bairwa, Yogesh Motwani
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引用次数: 0
Psychiatric morbidity among patients suffering from Vitiligo 白癜风患者的精神病发病率
Pub Date : 2023-11-01 DOI: 10.4103/ipj.ipj_220_23
Sandeep Kapur, Ekram Goyal, Ajay Kumar, Alka Puria, Richa Raj
Background: Vitiligo is a chronic acquired, stigmatizing disease characterized by discoloration of skin and mucous membranes. Patients suffering from this condition suffer from a lack of confidence and psychological stress. Aim: To assess depression, anxiety, and social anxiety among patients suffering from vitiligo. Material and Method: This hospital-based cross-sectional, observational, descriptive study was carried out in a tertiary care center on 100 patients suffering from vitiligo, who were consecutively enrolled after informed consent from the outpatient department (OPD) of the dermatology department. Permission was obtained from the institutional ethics committee Diagnosis of vitiligo was made by two consultants from the department of dermatology. Sociodemographic variables were recorded in the sociodemographic form. The General Health Questionnaire-12 (GHQ-12) was applied to all 100 patients. Patients who scored >3 on GHQ-12 were further subjected to the Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), and Social Interaction Anxiety Scale. Results were statistically analyzed on SPSS-22.0 (IBM, Armonk, USA). Results: Of all the patients, 55% (n = 55) had a GHQ score >3 (i.e., Psychiatric morbidity was present in 55% of patients.). Out of 50 patients in the age group of 18–25 years, 41 patients in the age groups of 26–35 years, and 9 patients in the age groups of 36–45 years, 22 (44%), 17 (42.1%), and 6 patients had psychiatric morbidity, respectively. Of the total number of patients, 46% had depression according to the HAM-D scale. Of all the patients, 18% had mild, 22% had moderate, and 6% had severe depression. Age-wise analysis showed that out of 50 patients in the age group of 18–25 years, 41 patients in the age group of 26–35 years, and 9 patients in the age group of 36–45 years, 22 (44%), 20 (48.7%), and 4 patients had depression, respectively. Of the patients who had depression, 39% were male and 58% were female. On HAM-A, 47% of the patients had anxiety; 33% had mild, 12% had moderate, and 2% had severe anxiety. Age-wise analysis showed that out of 50 patients in the age group of 18–25, 41 patients in the age group of 26–35 years, and 9 patients in the age group of 36–45 years, 20 (40%), 23 (56.1%), and 3 patients had anxiety, respectively. On SIAS, 36% of the patients had social anxiety. Out of 50 patients in the age group of 18–25 years, 41 patients in the age group of 26–35 years, and 9 patients in the age group of 36–45 years, 23 (46%), 9 (7.8%) and 4 patients had social anxiety, respectively. According to gender-wise distribution, 17% of male and 63% of female patients had social anxiety. Conclusion: A high prevalence of anxiety, depression, and social anxiety has been observed in this present study. Therefore, importance should be given to psychiatric evaluation of such patients and, if required, necessary interventions should be undertaken to improve their quality of life.
背景:白癜风是一种以皮肤和粘膜脱色为特征的慢性后天性污名化疾病。该病患者缺乏自信,心理压力大。目的:评估白癜风患者的抑郁、焦虑和社交焦虑。材料与方法:这项基于医院的横断面、观察性、描述性研究在一家三级医疗中心进行,100 名白癜风患者在获得皮肤科门诊部(OPD)的知情同意后连续入组。这些患者在获得皮肤科门诊部(OPD)的知情同意后连续入选,并获得了机构伦理委员会的许可,由皮肤科的两名顾问进行白癜风诊断。社会人口学变量记录在社会人口学表格中。所有 100 名患者均采用了《一般健康问卷-12》(GHQ-12)。对 GHQ-12 得分超过 3 分的患者进一步进行了汉密尔顿抑郁评定量表(HAM-D)、汉密尔顿焦虑评定量表(HAM-A)和社会交往焦虑量表的测试。结果通过 SPSS-22.0 (IBM,美国阿蒙克)进行统计分析。结果在所有患者中,55%(n = 55)的 GHQ 得分大于 3(即 55% 的患者存在精神疾病)。在 18-25 岁年龄组的 50 名患者、26-35 岁年龄组的 41 名患者和 36-45 岁年龄组的 9 名患者中,分别有 22 名(44%)、17 名(42.1%)和 6 名患者患有精神疾病。根据 HAM-D 量表,46%的患者患有抑郁症。在所有患者中,18% 患有轻度抑郁症,22% 患有中度抑郁症,6% 患有重度抑郁症。年龄分析显示,在 50 名 18-25 岁、41 名 26-35 岁和 9 名 36-45 岁的患者中,分别有 22 人(44%)、20 人(48.7%)和 4 人患有抑郁症。在抑郁症患者中,39% 为男性,58% 为女性。在 HAM-A 中,47% 的患者有焦虑症;33% 有轻度焦虑症,12% 有中度焦虑症,2% 有重度焦虑症。年龄分析显示,在 50 名 18-25 岁、41 名 26-35 岁和 9 名 36-45 岁的患者中,分别有 20 人(40%)、23 人(56.1%)和 3 人患有焦虑症。在 SIAS 中,36% 的患者患有社交焦虑症。在 50 名 18-25 岁、41 名 26-35 岁和 9 名 36-45 岁的患者中,分别有 23 人(46%)、9 人(7.8%)和 4 人患有社交焦虑症。从性别分布来看,17%的男性患者和 63%的女性患者患有社交焦虑症。结论本研究观察到焦虑、抑郁和社交焦虑的高发病率。因此,应重视对这类患者进行精神评估,如有必要,应采取必要的干预措施来改善他们的生活质量。
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引用次数: 0
Tobacco and alcohol use among adolescents in Northern India 印度北部青少年的烟酒使用情况
Pub Date : 2023-11-01 DOI: 10.4103/ipj.ipj_200_23
Sadhana Lakhute, Hetal K Rathod, Suman Ray, Tanvi Lijhara, Kshitij Anand Agarwal, Kajal Srivastava
Background: Alcohol and cigarette usage are major public health issues that particularly affect young people worldwide. Because most users begin using these drugs well before the age of 18, there are significant psychosocial and health consequences. This study seeks to identify the incidence of underage drinking and smoking in northern India and the multiple risk factors associated with this exposure. Materials and Methods: A cross-sectional study was conducted on adolescents (13–18 years) from Northern India, to assess their knowledge, attitude, and practice of usage of alcohol and tobacco. The study was conducted using a semi-structured questionnaire for interview purposes and analyzed via Epi Info version 7. Results: The mean age of the participants was 16.15 (1.34) years, of which 65.74% are males and 34.26% are females. 18.25% of students stay in a hostel. Of 108 participants, about 24.07% of students have tried their first cigarette before 18 years of age. 28.70% of students have people in their homes, and 41.67% have friends who use tobacco. Among the 108 respondents, 26.85% of students have tried or used alcohol before 18 years of age. Conclusion: It is crucial to create preventive techniques to lessen tobacco use in light of the significant negative health effects that come along with tobacco addiction. Spreading awareness among at-risk children and adolescents by limiting advertising and promotional efforts, early user detection and treatment are all examples of preventive techniques.
背景:酗酒和吸烟是主要的公共健康问题,对全世界的年轻人影响尤为严重。由于大多数使用者远在 18 岁之前就开始使用这些药物,因此会产生严重的社会心理和健康后果。本研究旨在确定印度北部未成年人饮酒和吸烟的发生率,以及与这种接触相关的多种风险因素。材料和方法:对印度北部的青少年(13-18 岁)进行了一项横断面研究,以评估他们对烟酒的认识、态度和使用习惯。研究采用半结构式问卷进行访谈,并通过 Epi Info 第 7 版进行分析。研究结果参与者的平均年龄为 16.15 (1.34)岁,其中 65.74% 为男性,34.26% 为女性。18.25%的学生住在宿舍。在 108 名参与者中,约 24.07% 的学生在 18 岁前尝试过第一次吸烟。28.70%的学生家中有人吸烟,41.67%的学生有朋友吸烟。在 108 名受访者中,26.85% 的学生在 18 岁前尝试过或使用过酒精。结论鉴于烟草成瘾对健康造成的重大负面影响,制定减少烟草使用的预防技术至关重要。通过限制广告和促销活动来提高高危儿童和青少年的意识,及早发现和治疗烟草使用者,这些都是预防技术的范例。
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引用次数: 0
The attitude of medical undergraduate students from North India toward transgender and change thereafter by educational intervention 北印度医学本科生对变性人的态度及其后通过教育干预发生的变化
Pub Date : 2023-11-01 DOI: 10.4103/ipj.ipj_194_23
Harshdeep Kaur, Rajnish Raj, Namita Sharma, Jaskaran Singh, Ekram Goyal
Background: There is a widespread gap among medical professionals about transgender, and it needs to be addressed through proper educational intervention to inculcate positive attitudes toward transgender people. Aim: This study aimed to assess the attitude of medical undergraduate students toward transgender and change thereafter by educational intervention. Materials and Methods: A total of 169 final-year undergraduate students (aged 22–25 years; 50.3% males; all having heterosexual orientation) were assessed for their attitudes toward transgender people using the Genderism and Transphobia Scale (GTS) and Attitude toward Transgender Individuals Scale (ATTIS). Subsequently, an educational intervention was conducted. The attitude scores were again evaluated immediately and after one month of post-intervention. A paired t-test, independent-samples t-test, and analysis of variance (ANOVA) were used to compare the data. Results: Mean ATTIS and GTS scores before intervention were 67.02 ± 9.20 and 80.84 ± 26.07, respectively. After the educational intervention, these scores were 79.27 ± 7.18 and 63.20 ± 12.11, respectively, thus showing a significant change in both scores. The change in GTS score was significantly higher in males than in females (P < 0.001) and in urban than in rural residents (P = 0.017). No significant association of demographic factors was observed concerning the change in ATTIS scores. On evaluating the recall value, no significant decline in GTS or ATTIS scores was observed following a one month of interval. Conclusion: There is a need to positively reinforce these changes brought about by educational intervention in the attitude of undergraduate medical students toward transgender people. Such cognitive gains are achievable in developing a humanistic society.
背景:医学专业人员对变性人的认识普遍存在差距,这需要通过适当的教育干预来解决,以灌输对变性人的积极态度。目的:本研究旨在评估医学本科生对变性人的态度,并通过教育干预改变他们的态度。材料与方法:使用性别主义和跨性别恐惧症量表(GTS)和对跨性别者的态度量表(ATTIS)评估了 169 名本科应届生(22-25 岁;50.3% 为男性;均为异性恋倾向)对跨性别者的态度。随后,进行了教育干预。在干预后的第一时间和一个月后,再次对态度评分进行评估。数据比较采用了配对 t 检验、独立样本 t 检验和方差分析(ANOVA)。结果干预前的 ATTIS 和 GTS 平均得分分别为 67.02 ± 9.20 和 80.84 ± 26.07。教育干预后,这两项得分分别为(79.27 ± 7.18)和(63.20 ± 12.11),因此这两项得分均有显著变化。男性的 GTS 分数变化明显高于女性(P < 0.001),城市居民的 GTS 分数变化明显高于农村居民(P = 0.017)。人口统计学因素与 ATTIS 分数的变化无明显关联。在评估回忆值时,没有发现间隔一个月后 GTS 或 ATTIS 分数有明显下降。结论:有必要通过教育干预积极加强本科医学生对变性人态度的改变。在发展人文社会的过程中,这种认知上的进步是可以实现的。
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引用次数: 0
Childhood trauma and bipolar affective disorder: Is there a linkage? 童年创伤与双相情感障碍:两者之间有联系吗?
Pub Date : 2023-11-01 DOI: 10.4103/ipj.ipj_206_23
V. Chauhan, Markanday Sharma, K. Chatterjee, J. Prakash, K. Srivastava, Suprakash Chaudhury
Bipolar affective disorder (BPAD) is a major psychiatric illness impairing the quality of life. The etiology of BPAD is influenced by different factors possibly related to gene-environment interactions. Approximately 30% to 50% of individuals with BPAD have experienced some traumatic event in childhood. Serious adverse experiences that children may suffer early in life are often described as childhood trauma (CT). It includes physical, emotional, and sexual abuse and physical and emotional neglect. CT is linked with an elevated risk of developing BPAD. Childhood adversities play a role in modulating the early onset of illness, increased number of depressive episodes, increased suicide attempts, and other clinical severity of BPAD. Hospital-based studies comprising heterogeneous populations had researched the specific role of each trauma subtype as a predisposing factor for BPAD. Identifying and addressing CT through early intervention methods may prevent the future development of chronic disorders like BPAD. This review article is an attempt to explore and highlight the existing literature regarding the association of different subtypes of CT with BPAD.
躁郁症(BPAD)是一种严重影响生活质量的精神疾病。躁郁症的病因受不同因素的影响,可能与基因和环境的相互作用有关。大约 30%至 50%的 BPAD 患者在童年时期经历过一些创伤事件。儿童早期可能遭受的严重不良经历通常被描述为儿童创伤(CT)。它包括身体、情感和性虐待,以及身体和情感上的忽视。童年创伤与罹患 BPAD 的风险升高有关。童年时期的逆境对早发性疾病、抑郁发作次数增加、自杀企图增加以及 BPAD 的其他临床严重性起着调节作用。由不同人群组成的基于医院的研究对每种创伤亚型作为 BPAD 易感因素的具体作用进行了研究。通过早期干预方法来识别和解决 CT 问题,可以预防 BPAD 等慢性疾病在未来的发展。这篇综述文章试图探讨和强调有关不同亚型 CT 与 BPAD 相关性的现有文献。
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引用次数: 0
Study of knowledge, attitude, and perception toward LGBTQ people amongst medical students 关于医学生对 LGBTQ 的了解、态度和看法的研究
Pub Date : 2023-11-01 DOI: 10.4103/ipj.ipj_219_23
Reeva Sorathiya, Anup Bharati, Ayushree Patil, S. Gorade
Background: People across cultures have had negative stereotypes, prejudice, and discriminatory attitudes toward the LGBTQ community for many years. Unfortunately, this perception exists within the medical fraternity as well, which in turn has a negative impact on the provision of healthcare facilities to individuals. Change in awareness and perception of LGBTQ among medical undergraduate students may remedy the situation. Aim: To find out the knowledge, attitude, and perception of medical graduates toward the LGBTQ community. Materials and Methods: The study is a cross-sectional observation study and was designed as an online survey using stratified random sampling incorporating the questions from California State University, Northridge (CSUN) questionnaire, Acceptance of Homosexuals (AHO), Homosexuality Attitude Scale (HAS), and relevant sociodemographic details. The data were collected using Google Forms for 3 months. Result: A total of 300 medical undergraduate students were included in the study. Around 87.6% (n = 263) of participants are comfortable having a friend with a homosexual orientation in their circle and 63% (n = 189) disagree that the acceptance of LGBTQ people has anything to do with the morality of our society. Conclusion: Although the overall knowledge and attitude of medical graduates toward LGBTQ is positive, a considerable percentage of students have negative attitudes. Despite the overwhelmingly accepting attitudes and perceptions, some individuals are slightly reluctant to interact comfortably with LGBTQ people. Medical students need to be trained to maintain a non-homophobic attitude.
背景:多年来,不同文化背景下的人们一直对 LGBTQ 群体抱有负面的成见、偏见和歧视态度。不幸的是,医学界也存在这种观念,这反过来又对为个人提供医疗保健设施产生了负面影响。医学本科生对 LGBTQ 的认识和看法的改变可能会纠正这种情况。目的:了解医科毕业生对 LGBTQ 群体的认识、态度和看法。材料与方法:本研究是一项横断面观察研究,采用分层随机抽样的方式进行在线调查,调查内容包括加州州立大学北岭分校(CSUN)问卷、同性恋者接受度(AHO)、同性恋态度量表(HAS)以及相关社会人口学细节。数据使用谷歌表格收集,为期 3 个月。研究结果共有 300 名医学本科生参与了研究。约 87.6%(n = 263)的参与者认为在自己的圈子里有同性恋倾向的朋友是件舒服的事,63%(n = 189)的参与者不同意接受 LGBTQ 与社会道德有关。结论尽管医学毕业生对 LGBTQ 的总体认识和态度是积极的,但仍有相当比例的学生持消极态度。尽管绝大多数人的态度和观念都是接受的,但有些人还是不太愿意与 LGBTQ 进行舒适的互动。医科学生需要接受培训,以保持不仇视的态度。
{"title":"Study of knowledge, attitude, and perception toward LGBTQ people amongst medical students","authors":"Reeva Sorathiya, Anup Bharati, Ayushree Patil, S. Gorade","doi":"10.4103/ipj.ipj_219_23","DOIUrl":"https://doi.org/10.4103/ipj.ipj_219_23","url":null,"abstract":"Background: People across cultures have had negative stereotypes, prejudice, and discriminatory attitudes toward the LGBTQ community for many years. Unfortunately, this perception exists within the medical fraternity as well, which in turn has a negative impact on the provision of healthcare facilities to individuals. Change in awareness and perception of LGBTQ among medical undergraduate students may remedy the situation. Aim: To find out the knowledge, attitude, and perception of medical graduates toward the LGBTQ community. Materials and Methods: The study is a cross-sectional observation study and was designed as an online survey using stratified random sampling incorporating the questions from California State University, Northridge (CSUN) questionnaire, Acceptance of Homosexuals (AHO), Homosexuality Attitude Scale (HAS), and relevant sociodemographic details. The data were collected using Google Forms for 3 months. Result: A total of 300 medical undergraduate students were included in the study. Around 87.6% (n = 263) of participants are comfortable having a friend with a homosexual orientation in their circle and 63% (n = 189) disagree that the acceptance of LGBTQ people has anything to do with the morality of our society. Conclusion: Although the overall knowledge and attitude of medical graduates toward LGBTQ is positive, a considerable percentage of students have negative attitudes. Despite the overwhelmingly accepting attitudes and perceptions, some individuals are slightly reluctant to interact comfortably with LGBTQ people. Medical students need to be trained to maintain a non-homophobic attitude.","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139302037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of internet gaming addiction and its association with sleep quality in medical students 医学生网络游戏成瘾及其与睡眠质量的关系
Pub Date : 2023-11-01 DOI: 10.4103/ipj.ipj_236_23
Makhan Shakya, Rajesh Singh, Amrita Chauhan, Daisy Rure, Akshat Shrivastava
Background: In Asia, there are approximately 2.3 billion internet users. Addiction to internet gaming takes a multifaceted toll on an individual's physical and mental well-being, casting a long shadow over their daily endeavors and also their sleep cycle. Aim: To study the prevalence of internet gaming addiction and how it affects sleep quality in medical students. Materials and Methods: A cross-sectional study was performed with a sample size (n = 112) in the Government Medical College, Datia (M.P.), and data were collected using a semi-structured proforma including the Internet Gaming Disorder Scale and Mini Sleep Questionnaire in the study population. Results: In the study population with age group 18–28 years (mean age: 21 ± 1.7 years), the majority of them belong to the Hindu religion (91.1%), nuclear family (66.1%), and urban community (75.9%). Most students (n = 74) had mild to moderate sleep difficulty related to internet gaming addiction, that is, 65.1%. The most common response was “sometimes” on the Internet Gaming Disorder Scale. A significant association was observed between gaming disorder and parameters of sleep mainly in waking up too early, daytime sleepiness, snoring, feeling tired, and headache upon waking up with gaming disorder. Conclusion: Among medical students, gaming addiction is significantly associated with poor sleep quality. Steps need to be taken to promote healthy internet use to improve sleep quality and mitigate negative effects to avoid long-term health impacts.
背景:亚洲约有 23 亿互联网用户。沉迷于网络游戏会对个人的身心健康造成多方面的影响,给他们的日常工作和睡眠周期蒙上一层阴影。目的:研究医学生网络游戏成瘾的普遍程度及其对睡眠质量的影响。材料与方法:在达蒂亚(M.P.)政府医学院进行了一项横断面研究,样本量(n = 112),使用半结构式问卷收集数据,包括网络游戏障碍量表和迷你睡眠问卷。研究结果研究对象的年龄段为 18-28 岁(平均年龄:21 ± 1.7 岁),其中大多数人信奉印度教(91.1%)、核心家庭(66.1%)和城市社区(75.9%)。大多数学生(n = 74)有轻度至中度睡眠困难,与网络游戏成瘾有关,占 65.1%。在网络游戏成瘾量表中,最常见的回答是 "有时"。研究发现,游戏障碍与睡眠参数之间存在明显关联,主要表现在过早醒来、白天嗜睡、打鼾、疲倦感和醒来后头痛。结论在医学生中,游戏成瘾与睡眠质量差有很大关系。需要采取措施促进健康上网,以改善睡眠质量,减轻负面影响,避免对健康造成长期影响。
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引用次数: 0
Guided imagery for anxiety disorder: Therapeutic efficacy and changes in quality of life 引导想象治疗焦虑症:治疗效果和生活质量的变化
Pub Date : 2023-11-01 DOI: 10.4103/ipj.ipj_238_23
Dolly Kumari, J. Patil
Background: Patients with anxiety disorder were showing severity of anxiety symptoms as well as poor quality of life. Guided imagery (GI) provides immediate relaxation, and improves the severity of anxiety symptoms and the quality of life of patients with anxiety disorder. Anxiety is a basic emotion that is required as a motivation for everyday work of life. Anxiety presents a complex cognitive, affective, physiological, and behavioral response that is related to future harm (real or perceived). Aim: To study the efficacy of GI intervention on patients with anxiety disorder and their quality of life. Materials and Methods: This longitudinal, interventional study was done in a state institute of mental health, psychiatric unit on 20 patients (outpatients) with anxiety disorder, diagnosed according to diagnostic criteria of research ICD-10 DCR. Patients were assessed using a sociodemographic and clinical data sheet, Hamilton anxiety scale, and World Health Organization QOL instrument, short-form (WHOQOL-BREF), Hindi version. Results: Patients with anxiety disorder in the experimental group improved as compared with the control group significantly. The mean QOL-BREF score was also improved after intervention in the intervention group. Conclusion: GI intervention helps reduce the severity of anxiety symptoms and improve the quality of life in patients with anxiety disorder.
背景焦虑症患者焦虑症状严重,生活质量低下。引导想象(GI)能让焦虑症患者立即放松,并改善焦虑症状的严重程度和生活质量。焦虑是一种基本情绪,是日常生活工作所需的动力。焦虑是一种复杂的认知、情感、生理和行为反应,与未来的伤害(真实的或感知到的)有关。目的:研究 GI 干预对焦虑症患者的疗效及其生活质量。材料与方法:这项纵向干预研究是在一家州立精神卫生研究所的精神科进行的,研究对象是 20 名焦虑症患者(门诊患者),根据 ICD-10 DCR 研究的诊断标准进行诊断。研究人员使用社会人口学和临床数据表、汉密尔顿焦虑量表和世界卫生组织 QOL 短式问卷(WHOQOL-BREF)印地语版对患者进行了评估。结果与对照组相比,实验组焦虑症患者的病情明显好转。干预后,干预组的 QOL-BREF 平均得分也有所提高。结论GI 干预有助于减轻焦虑症患者焦虑症状的严重程度并提高其生活质量。
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引用次数: 0
Association between thyroid functions, cognition, and functional connectivity of the brain in early-course schizophrenia: A preliminary study 早期精神分裂症患者的甲状腺功能、认知能力和大脑功能连接之间的关系:初步研究
Pub Date : 2023-11-01 DOI: 10.4103/ipj.ipj_198_23
A. B. George, RamPratap Beniwal, Sadhana Singh, T. Bhatia, Subhash Khushu, S. Deshpande
Background: The functional outcome of the debilitating mental illness schizophrenia (SZ) has an integral role in cognition. The thyroid hormone has a vital role in the developmental stages and functioning of the human brain. Aim: This study aimed to evaluate the relationship between thyroid functions, cognition, and functional imaging of the brain in persons with SZ. Materials and Methods: Sixty SZ (Diagnostic and Statistical Manual (DSM-5)) persons, aged 18–50 years of both genders, were recruited in this cross-sectional observational study. Positive and Negative Syndrome Scale (PANSS) and Trail Making Tests (TMTs) A and B were administered to all patients. To assess the level of thyroid hormone, a test was conducted. Functional connectivity of the brain was assessed using resting-state functional magnetic resonance imaging (rs-fMRI). Data analysis was performed by descriptive and analytical statistical methods. FSL version 5.9 (FMRIB's) software was used for analyses of fMRI neuroimages. Results: There were no significant differences between the two populations on sociodemographic factors. The average value for thyroid-stimulating hormone (TSH) in the hypothyroid group (n = 12) and the euthyroid group (n = 47) was 8.38 mIU/l and 2.44 mIU/l, respectively. The average time in seconds for TMT-A and TMT-B was 87.27 and 218.27 in the hypothyroid group and 97.07 and 293.27 in the euthyroid group, respectively. Similarly, in the sample matched on age, gender, and age at onset of illness, there were no significant differences in demographic and clinical factors and resting-state network (RSN) between the hypothyroid (N = 10) and euthyroid (N = 10) groups. Conclusion: No differences were found in the functional brain network between the hypothyroid and euthyroid groups as the study sample did not include clinically hypothyroid persons with SZ.
背景:使人衰弱的精神疾病精神分裂症(SZ)的功能结果与认知有着不可分割的关系。甲状腺激素对人脑的发育阶段和功能起着至关重要的作用。目的:本研究旨在评估精神分裂症患者的甲状腺功能、认知能力和大脑功能成像之间的关系。材料与方法:这项横断面观察性研究共招募了60名SZ(《诊断与统计手册》(DSM-5))患者,年龄在18-50岁之间,男女不限。研究人员对所有患者进行了阳性和阴性综合量表(PANSS)以及追踪测试(TMTs)A和B的测试。为了评估甲状腺激素水平,还进行了一项测试。使用静息态功能磁共振成像(rs-fMRI)评估大脑的功能连接性。数据分析采用描述性和分析性统计方法。FSL 5.9 版(FMRIB's)软件用于分析 fMRI 神经图像。结果两种人群的社会人口学因素无明显差异。甲状腺功能减退组(12 人)和甲状腺功能正常组(47 人)的促甲状腺激素(TSH)平均值分别为 8.38 mIU/l 和 2.44 mIU/l。甲减组 TMT-A 和 TMT-B 的平均时间(秒)分别为 87.27 和 218.27,甲状腺功能正常组分别为 97.07 和 293.27。同样,在年龄、性别和发病年龄相匹配的样本中,甲状腺功能减退组(10 人)和甲状腺功能亢进组(10 人)在人口统计学和临床因素以及静息状态网络(RSN)方面没有显著差异。结论由于研究样本不包括临床甲状腺功能减退的SZ患者,因此甲状腺功能减退组和甲状腺功能亢进组在大脑功能网络方面没有发现差异。
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引用次数: 0
Translation and psychometrics of the Bengali adaptation of Coronavirus Anxiety Scale 孟加拉语改编版冠状病毒焦虑量表的翻译和心理测量学研究
Pub Date : 2023-11-01 DOI: 10.4103/ipj.ipj_235_23
Tahoora Ali, Suprakash Chaudhury, Santosh Kumar, Vidhata Dixit, C. Diwan, Parisha Kelkar
Background: The Coronavirus Anxiety Scale (CAS) was developed in April 2020 as an instrument to gauge the symptoms of stress and anxiety occurring secondary to the COVID-19 pandemic. It was constructed using the English language due to which its application to a multi-linguistic country like India became a hindrance. Aim: To establish psychometric validity and reliability of the Bengali translation of CAS. Materials and Methods: Experts well-versed in the English and Bengali languages translated CAS from English to Bengali. This was followed by further correction by forward and backward translation processes until a version with high accuracy and low redundancy was procured. The original scale was applied to 91 volunteers, and the translated version was applied to the same group after 14 days. Results: The mean scores of the original version and the translated version showed a significant correlation. The Bengali version of CAS had high internal consistency, significant concurrent validity, and acceptable split-half reliability. It was hence deemed easily understandable and capable of measuring anxiety due to COVID-19 similar to the original scale. Conclusion: The Bengali translation of the CAS can be accurately used to assess symptoms of anxiety and stress with high reliability and validity in those who are able to read the Bengali language.
背景:冠状病毒焦虑量表(CAS)于 2020 年 4 月编制完成,用于测量因 COVID-19 大流行而产生的压力和焦虑症状。该量表使用英语编制,因此在印度这样的多语言国家使用该量表存在障碍。目的:确定 CAS 孟加拉语译本的心理测量有效性和可靠性。材料与方法:精通英语和孟加拉语的专家将 CAS 从英语翻译成孟加拉语。然后通过正向和反向翻译过程进行进一步修正,直到获得一个准确性高、冗余度低的版本。原量表适用于 91 名志愿者,14 天后,翻译版本适用于同一组志愿者。结果显示原始版本和翻译版本的平均得分显示出显著的相关性。孟加拉语版 CAS 具有较高的内部一致性、显著的并发效度和可接受的分半信度。因此,孟加拉语版 CAS 与原量表相似,易于理解,能够测量 COVID-19 导致的焦虑。结论孟加拉语翻译的 CAS 可以准确地用于评估焦虑和压力症状,对于能够阅读孟加拉语的人来说,具有很高的信度和效度。
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引用次数: 0
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Industrial Psychiatry Journal
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