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Effect of herbal medicine (Jodeungsan) on migraine: A double-blind randomized clinical trial 中草药(九登山)对偏头痛的影响:一项双盲随机临床试验
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.imr.2022.100885
Seyoung Kim , Jihye Seo , Cheol-hyun Kim , Hyun-Kyung Sung , Ho-Yeon Go , Woo Sang Jung , Seungwon Kwon , Minjung Kwak , Sangkwan Lee

Background

Migraine is a relatively common disease that has a significant effect on the daily activities of affected individuals. The purpose of this study was to explore the effects of herbal medicine (Jodeungsan, JDS) on migraine.

Methods

Sixty-four patients with migraine were recruited and randomized to either the JDS or placebo group at a 1:1 ratio. The subjects received JDS or placebo daily for four weeks. The primary outcome was a change in the number of headache attack days (HADs), and the secondary outcome measures were the headache impact test (HIT), migraine-specific quality of life (MSQoL), the deficiency and excess pattern identification questionnaire (DEPIQ), the cold and heat pattern identification questionnaire (CHPIQ), and the blood stasis pattern questionnaire (BSPQ).

Results

In all, 61 of the 64 patients took the investigational drugs for four weeks. The number of HADs did not significantly differ between the JDS and placebo groups at the end of the study. However, the HIT and MSQoL results showed significant improvement over the baseline in both groups.

Conclusions

JDS did not have a significant effect on chronic migraine. Larger studies are needed to confirm this result.

Trial registration

Clinical Research Information Service (https://cris.nih.go.kr/): KCT0003121.

背景:偏头痛是一种相对常见的疾病,对患者的日常活动有显著影响。本研究的目的是探讨中草药(Jodeungsan, JDS)对偏头痛的影响。方法招募64例偏头痛患者,按1:1的比例随机分为JDS组和安慰剂组。受试者每天服用JDS或安慰剂,持续四周。主要结局指标为头痛发作天数(HADs)的变化,次要结局指标为头痛影响试验(HIT)、偏头痛特异性生活质量(MSQoL)、虚虚证型识别问卷(DEPIQ)、寒热证型识别问卷(CHPIQ)和血瘀证型调查问卷(BSPQ)。结果64例患者中,61例患者连续用药4周。在研究结束时,JDS组和安慰剂组的HADs数量没有显著差异。然而,HIT和MSQoL结果显示两组均较基线有显著改善。结论sjds对慢性偏头痛无明显治疗作用。需要更大规模的研究来证实这一结果。临床研究信息服务(https://cris.nih.go.kr/): KCT0003121)。
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引用次数: 0
Robustness of meta-analysis results in Cochrane systematic reviews: A case for acupuncture trials Cochrane系统评价中meta分析结果的稳健性:一个针灸试验的案例
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.imr.2022.100890
Jiyoon Won

Background

Fragility index (FI) refers to the smallest value that change statistical significance of study results. Meta-analyses of Cochrane systematic reviews are considered as the best evidence for stake holders because they enable effect size estimation that cannot be derived by individual studies, particularly in the field of complementary and integrative medicine (CIM). Thus, this study aimed to evaluate robustness of meta-analysis in Cochrane systematic reviews of acupuncture, one of the most used CIM treatment, using FI of meta-analysis.

Methods

Meta-analyses of acupuncture Cochrane systematic reviews with binary benefit outcome measures were searched in PubMed, Embase, and CENTRAL and subject to analysis. Randomized clinical trials (RCTs) or quasi RCTs adopted penetrating needles as treatment and compared with controls such as sham acupuncture, usual care, and active control were included. FI of meta-analyses was calculated in web (https://clinicalepidemio.fr/fragility_ma/); and fragility quotient (FQ) was calculated by dividing FI by total sample size of meta-analysis.

Results

Of 248 retrieved studies, 12 Cochrane systematic reviews with 48 meta-analyses were analyzed. The median FI for statistically significant and non-significant meta-analyses was 7 [interquartile range: 3 - 12] and 6 [interquartile range: 3 - 10]. FQ was similar irrespective of statistical significance. Among controls, meta-analyses adopting sham acupuncture displayed the widest range of FI and FQ.

Conclusion

Robustness of meta-analyses in Cochrane systematic reviews for acupuncture was similar irrespective of statistical significance. Impact of control intervention cannot be determined in this study. As FI enables intuitive interpretation, applications for CIM field can be useful.

脆弱性指数(FI)是指研究结果改变统计显著性的最小值。Cochrane系统评价的荟萃分析被认为是利益相关者的最佳证据,因为它们使个体研究无法得出的效应大小估计成为可能,特别是在补充和综合医学(CIM)领域。因此,本研究旨在利用meta分析的FI来评估针灸(最常用的CIM治疗方法之一)在Cochrane系统评价中meta分析的稳健性。方法在PubMed、Embase和CENTRAL中检索具有二元获益结局指标的Cochrane系统评价并进行分析。随机临床试验(rct)或准rct采用穿透针作为治疗,并与假针灸、常规护理、主动对照等对照进行比较。meta分析的FI在web (https://clinicalepidemio.fr/fragility_ma/)中计算;脆弱性商(FQ)由FI除以meta分析的总样本量计算。结果在248项被检索的研究中,对12项Cochrane系统评价和48项meta分析进行了分析。统计显著和非显著荟萃分析的中位FI分别为7[四分位数范围:3 - 12]和6[四分位数范围:3 - 10]。FQ相似,无统计学意义。在对照组中,采用假针灸的meta分析显示FI和FQ的范围最广。结论针灸的Cochrane系统评价meta分析的稳健性相似,无统计学意义。本研究无法确定控制干预的影响。由于FI能够实现直观的解释,因此CIM领域的应用程序非常有用。
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引用次数: 0
Effectiveness of herbal medicines to prevent and control symptoms of urinary tract infections and to reduce antibiotic use: A literature review 草药预防和控制尿路感染症状和减少抗生素使用的有效性:文献综述
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.imr.2022.100892
Herman van Wietmarschen , Noortje van Steenbergen , Esther van der Werf , Erik Baars

Background

Antimicrobial resistance is a rapidly growing global issue affecting the effective treatment of infectious diseases. This provides a window of opportunity for the use and implementation of well researched effective complementary therapies such as herbal medicines. In this literature review, an overview is provided of the effectiveness of herbal medicine to control symptoms of urinary tract infections and reduce antibiotic use.

Methods

PubMed, CAM-Quest, CORE-Hom, ScienceDirect, CAMBase, Anthromedics.org and AnthroMedLibrary databases were searched for peer-reviewed meta-analyses, systematic reviews and randomized controlled trials from 2005 till 8 October 2020. Included were clinical studies on the use of herbal medicine for clinically diagnosed urinary tract infection with any control group except another herbal medicine. Study quality was assessed using the Joanna Briggs Institute critical appraisal tools.

Results

Of the 408 citations identified, 23 met the inclusion criteria: 5 meta-analyses, 3 systematic reviews and 15 randomized controlled trials. Of these studies 13 involved the use of cranberry products, 4 studies concerned traditional Chinese herbal medicines, and 6 studies dealt with other herbal medicines.

Conclusions

The latest published meta-analysis including 28 trials reports a clear benefit of Cranberry products for the prevention of recurrent UTIs in women. Five TCM formulas were found to be equally or more effective than antibiotics in the treatment of UTIs. Furthermore, Rosa canina seems to have the potential to prevent UTI in women undergoing a caesarean section. ‘Acidif Plus Tablets’ as well as ‘Canephron’ seem to be promising candidates for treating women with uncomplicated recurrent UTI.

抗生素耐药性是一个迅速增长的全球性问题,影响着传染病的有效治疗。这为使用和实施经过充分研究的有效补充疗法(如草药)提供了机会。在这篇文献综述中,概述了草药在控制尿路感染症状和减少抗生素使用方面的有效性。方法从2005年至2020年10月8日检索spubmed、CAM-Quest、core - hm、ScienceDirect、CAMBase、Anthromedics.org和AnthroMedLibrary数据库,检索同行评介的meta分析、系统评价和随机对照试验。包括在临床诊断为尿路感染的任何对照组中使用草药的临床研究,除了另一种草药。使用乔安娜布里格斯研究所的关键评估工具评估研究质量。结果在408篇文献中,23篇符合纳入标准:5篇荟萃分析、3篇系统评价和15篇随机对照试验。在这些研究中,13项研究涉及蔓越莓产品的使用,4项研究涉及传统中草药,6项研究涉及其他草药。最新发表的荟萃分析包括28项试验,报告了蔓越莓产品对预防女性复发性尿路感染的明显益处。五种中药方剂治疗尿路感染的效果与抗生素相同或更有效。此外,Rosa canina似乎具有预防剖腹产妇女尿路感染的潜力。“Acidif Plus片剂”和“Canephron”似乎是治疗女性无并发症复发性尿路感染的有希望的候选药物。
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引用次数: 3
The role of acupuncture and moxibustion in the treatment, prevention, and rehabilitation of patients with COVID-19: A scoping review 针灸在COVID-19患者的治疗、预防和康复中的作用:一项范围综述
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.imr.2022.100886
Mengjuan Ren , Yunlan Liu , Xiaojia Ni , Zhuoran Kuang , Xufei Luo , Yikai Zhang , Huishan Li , Yaolong Chen

Background

This study aims to summarize the available evidence and guideline/consensus recommendations for acupuncture and moxibustion in the treatment, prevention and rehabilitation of patients with coronavirus disease 2019 (COVID-19).

Methods

A scoping review was performed. Eight electronic databases and other related websites were searched. All studies related to acupuncture and moxibustion for COVID-19 were considered. Descriptive analysis was applied to analyze the all included studies and guideline recommendations.

Results

We ultimately included 131 eligible studies. The main topics of the included studies were the treatment (82.4%) and prevention (38.9%) of COVID-19. The most included studies were literature reviews (65, 49.6%), protocols of systematic reviews (20, 15.3%), and guidelines and consensuses (18, 13.7%). The 18 (13.7%) COVID-19 guidelines and consensuses included 47 recommendations on acupuncture and moxibustion, which focused on the treatment (21/47, 44.7%), rehabilitation (17/47, 36.2%) and prevention (6, 12.8%) of COVID-19 patients. Zusanli (ST36), Feishu (BL13), Guanyuan (RN4) were recommended mostly for the treatment, rehabilitation and prevention respectively.

Conclusions

Acupuncture and moxibustion are effective in the treatment of COVID-19 patients to some extent. However, more high-quality of clinical trials still needed to determine the feasibility of acupuncture and moxibustion in COVID-19 patients to better guide clinical practice.

Study registration

Open Science Framework Registries (Registration DOI: 10.17605/OSF.IO/Z35WN; https://osf.io/z35wn).

本研究旨在总结针灸治疗、预防和康复冠状病毒病2019 (COVID-19)患者的现有证据和指南/共识建议。方法进行范围综述。检索了8个电子数据库和其他相关网站。纳入了所有与针灸治疗COVID-19相关的研究。采用描述性分析对所有纳入的研究和指南建议进行分析。结果我们最终纳入了131项符合条件的研究。纳入研究的主要主题是COVID-19的治疗(82.4%)和预防(38.9%)。纳入最多的研究是文献综述(65篇,49.6%)、系统评价方案(20篇,15.3%)和指南和共识(18篇,13.7%)。新冠肺炎指南和共识共18份(13.7%),其中针灸建议47项,重点关注新冠肺炎患者的治疗(21/47,44.7%)、康复(17/47,36.2%)和预防(6,12.8%)。分别推荐足三里(ST36)、肺舒(BL13)、冠源(RN4)进行治疗、康复和预防。结论针灸治疗新冠肺炎患者有一定疗效。但仍需要更多高质量的临床试验来确定针灸治疗新冠肺炎患者的可行性,以更好地指导临床实践。研究注册开放科学框架注册(注册DOI: 10.17605/OSF.IO/Z35WN;https://osf.io/z35wn)。
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引用次数: 9
Integrative medicine research for improving female reproductive health during COVID-19 新冠肺炎期间改善女性生殖健康的中西医结合研究
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.imr.2022.100894
Jue Zhou , Weihuan Hu , Fan Qu
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引用次数: 0
Randomized, single-blind, placebo-controlled trial on Hominis placenta extract pharmacopuncture for hot flashes in peri- and post-menopausal women Hominis胎盘提取物药物穿刺治疗绝经前后妇女潮热的随机、单盲、安慰剂对照试验
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.imr.2022.100891
Su-Ji Choi , Dong-Il Kim , Sang Ho Yoon , Chang-Min Choi , Jeong-Eun Yoo

Background

Hominis placenta pharmacopuncture is widely used for climacteric symptoms. This study examined the efficacy and safety of pharmacopuncture with PLC (the extract of Hominis placenta) on hot flashes for perimenopausal and postmenopausal women.

Methods

This study was a randomized placebo-controlled single-blind trial, which recruited 128 perimenopausal and postmenopausal women, randomly assigned to receive pharmacopuncture with PLC or normal saline (NS) for eight weeks. The primary outcome was the mean changes in the hot flash score (HFS) and the secondary outcomes were the mean changes in the Menopause Rating Scale (MRS), follicle-stimulating hormone (FSH) levels, and estradiol (E2) levels from baseline to eight weeks. Missing values were imputed using the last-observation-carried-forward method.

Results

After treatment (week 9), the HFS decreased significantly in both groups (p = 0.000). The residual HFS was 47.09 ± 41.39% and 56.45 ± 44.92 % in the PLC and control groups, respectively (p = 0.262). One month after the treatment (week 13), the score of the PLC group was reduced, but the score increased in the control group (p = 0.077). There were no statistically significant differences in the mean changes in MRS, FSH, and E2 between the two groups. No serious adverse events related to this trial were noted.

Conclusion

In this study, Hominis placenta extract pharmacopuncture did not differ significantly from NS in reducing the hot flash score. While this therapy appears safe, the potential for long-term effect of PLC extract needs to be examined in a large randomized controlled trial with appropriate controls.

Trial registration

Clinical Research Information Service, Republic of Korea, KCT0 0 03533.

人类胎盘药物穿刺术广泛应用于更年期症状的治疗。本研究考察了PLC(人胎盘提取物)药物穿刺治疗围绝经期和绝经后妇女潮热的有效性和安全性。方法本研究是一项随机安慰剂对照单盲试验,招募128名围绝经期和绝经后妇女,随机分配接受PLC或生理盐水(NS)药物穿刺,为期8周。主要结果是潮热评分(HFS)的平均变化,次要结果是绝经评分量表(MRS)、促卵泡激素(FSH)水平和雌二醇(E2)水平从基线到8周的平均变化。缺失值采用最后一次观测结转法进行估算。结果治疗后(第9周),两组患者HFS均显著降低(p = 0.000)。PLC组和对照组的残余HFS分别为47.09±41.39%和56.45±44.92% (p = 0.262)。治疗1个月后(第13周),PLC组评分降低,对照组评分升高(p = 0.077)。两组患者MRS、FSH、E2平均变化差异无统计学意义。本试验未发现严重不良事件。结论在本研究中,人胎素提取物药物穿刺在降低热闪评分方面与NS无显著差异。虽然这种疗法似乎是安全的,但PLC提取物的长期潜在效果需要在适当对照的大型随机对照试验中进行检验。韩国临床研究信息服务中心,KCT0 0 03533。
{"title":"Randomized, single-blind, placebo-controlled trial on Hominis placenta extract pharmacopuncture for hot flashes in peri- and post-menopausal women","authors":"Su-Ji Choi ,&nbsp;Dong-Il Kim ,&nbsp;Sang Ho Yoon ,&nbsp;Chang-Min Choi ,&nbsp;Jeong-Eun Yoo","doi":"10.1016/j.imr.2022.100891","DOIUrl":"10.1016/j.imr.2022.100891","url":null,"abstract":"<div><h3>Background</h3><p><em>Hominis placenta</em> pharmacopuncture is widely used for climacteric symptoms. This study examined the efficacy and safety of pharmacopuncture with PLC (the extract of <em>Hominis placenta</em>) on hot flashes for perimenopausal and postmenopausal women.</p></div><div><h3>Methods</h3><p>This study was a randomized placebo-controlled single-blind trial, which recruited 128 perimenopausal and postmenopausal women, randomly assigned to receive pharmacopuncture with PLC or normal saline (NS) for eight weeks. The primary outcome was the mean changes in the hot flash score (HFS) and the secondary outcomes were the mean changes in the Menopause Rating Scale (MRS), follicle-stimulating hormone (FSH) levels, and estradiol (E<sub>2</sub>) levels from baseline to eight weeks. Missing values were imputed using the last-observation-carried-forward method.</p></div><div><h3>Results</h3><p>After treatment (week 9), the HFS decreased significantly in both groups (<em>p</em> = 0.000). The residual HFS was 47.09 ± 41.39% and 56.45 ± 44.92 % in the PLC and control groups, respectively (<em>p</em> = 0.262). One month after the treatment (week 13), the score of the PLC group was reduced, but the score increased in the control group (<em>p</em> = 0.077). There were no statistically significant differences in the mean changes in MRS, FSH, and E<sub>2</sub> between the two groups. No serious adverse events related to this trial were noted.</p></div><div><h3>Conclusion</h3><p>In this study, <em>Hominis placenta</em> extract pharmacopuncture did not differ significantly from NS in reducing the hot flash score. While this therapy appears safe, the potential for long-term effect of PLC extract needs to be examined in a large randomized controlled trial with appropriate controls.</p></div><div><h3>Trial registration</h3><p>Clinical Research Information Service, Republic of Korea, KCT0 0 03533.</p></div>","PeriodicalId":13644,"journal":{"name":"Integrative Medicine Research","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7b/f8/main.PMC9634366.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40450133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Comparison of the acupuncture manipulation properties of traditional East Asian medicine and Western medical acupuncture 东亚传统医学与西医针灸手法特性比较
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.imr.2022.100893
Da-Eun Yoon, In-Seon Lee, Younbyoung Chae

Background

Acupuncture treatments frequently use manipulation techniques. The therapeutic advantages of acupuncture differ depending on the acupuncture manipulation. The purpose of this article was to compare manipulation techniques in traditional East Asian medicine (TEAM) and Western medical acupuncture (WMA).

Methods

Manipulation techniques in TEAM and WMA were compared according to purpose, modulating parameters, and indications. The practical understanding of manipulation in terms of acupuncture stimulation intensity was also explored. The TEAM manipulation techniques of twirling and lifting and thrusting are discussed in terms of the objectives of tonification and sedation.

Results

The main therapeutic effect of WMA is mediated through activation of the nervous system, which is achieved with adequate intensity of needling. The TEAM tonification and sedation techniques were designed to produce mild or intense stimulation, respectively, to elicit varying degrees of deqi sensation.

Conclusions

Further research is needed to clarify the differences between the TEAM and WMA practices, and to determine whether different needling manipulations affect treatment outcomes.

针灸治疗经常使用手法技术。针灸的治疗优势因针灸手法的不同而不同。本文的目的是比较传统东亚医学(TEAM)和西医针灸(WMA)的手法。方法根据目的、调节参数及适应证对TEAM和WMA的手法进行比较。探讨了针刺刺激强度对手法的实际理解。在团队操作技术的旋转和提升和推力方面讨论了补益和镇静的目标。结果WMA的主要治疗作用是通过激活神经系统来实现的,在适当的针刺强度下可以实现。TEAM的滋补和镇静技术分别设计为产生轻度或强烈的刺激,以引起不同程度的deqi感觉。结论TEAM与WMA针刺手法的差异,以及不同针刺手法对治疗效果的影响有待进一步研究。
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引用次数: 1
Prevalence and predictors of naturopathic practitioners’ self-reported practice behaviours: results of an international survey 自然疗法从业者自我报告的实践行为的患病率和预测因素:一项国际调查的结果
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.imr.2022.100897
Amie Steel , Iva Lloyd , Hope Foley , Matthew Leach

Background

The naturopathic workforce spans over 108 countries and is estimated to provide care to over 5.5 million patients globally per month. Despite such demand, naturopathic practitioners are not well integrated into mainstream health systems, in part due to poor knowledge about naturopathy among policy makers and other health professionals. This study aims to describe naturopathic practitioners’ practice behaviours and examine the characteristics that predict the use of naturopathic treatments and practices around the world.

Methods

An international cross-sectional online survey was distributed through World Naturopathic Federation membership organisations and social media accounts. Multivariate reverse stepwise logistic regression was undertaken to examine potential predictors of practice behaviours, adjusting for the influence of demographic and practice characteristics

Results

A response rate of 78.4% was achieved (n=478). Lifestyle modifications, dietary changes, nutritional products and herbal medicines were most consistently prescribed Always or Most of the time. At least one-half of participants discussed nine of the ten health topics during clinical practice Always or Most of the time. More than one-half (55.1%) of participants practiced in a location with statutory regulation/occupational certification. Compared to participants located in countries with voluntary certification/no regulation, those in countries with statutory registration/occupational licensing had higher odds of prescribing nutritional products (adjusted odds ratio (aOR)=2.5) or IV/injection therapies (aOR=18.4).

Conclusion

The findings of this study provide important insights into contemporary naturopathic practice behaviour, which may help to overcome misconceptions about such practice among other health professionals, policy makers and the community.

自然疗法从业人员遍布108个国家,估计每月为全球550多万患者提供护理。尽管有这样的需求,但自然疗法从业者并没有很好地融入主流卫生系统,部分原因是政策制定者和其他卫生专业人员对自然疗法的了解不足。本研究旨在描述自然疗法从业者的实践行为,并研究预测世界各地自然疗法治疗和实践使用的特征。方法通过世界自然疗法联合会会员组织和社交媒体账户进行国际横断面在线调查。采用多变量反向逐步logistic回归,对人口统计学和执业特征的影响进行校正,以检验执业行为的潜在预测因素。结果应答率为78.4% (n=478)。生活方式的改变、饮食习惯的改变、营养产品和草药的使用一直或大部分时间都是一致的。至少有一半的参与者在临床实践中总是或大部分时间讨论了10个健康主题中的9个。超过一半(55.1%)的参与者在有法定法规/职业认证的场所执业。与来自自愿认证/无监管国家的参与者相比,那些来自法定注册/职业许可国家的参与者开营养品处方的几率更高(调整优势比(aOR)=2.5)或静脉/注射疗法(aOR=18.4)。结论本研究的发现对当代自然疗法的实践行为提供了重要的见解,这可能有助于克服其他卫生专业人员、政策制定者和社区对自然疗法的误解。
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引用次数: 0
Enablers and barriers to evidence implementation in complementary medicine: A systematic review 辅助医学证据实施的推动因素和障碍:一项系统综述
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.imr.2022.100899
Matthew J. Leach , Yasamin Veziari

Background

Despite the push for complementary medicine (CM) practitioners to engage in evidence implementation, and arguments in support of evidence-based practice (EBP), uptake of EBP amongst most CM professions remains low. This review aimed to synthesise the evidence examining the barriers and enablers to evidence implementation in CM.

Methods

Any primary study examining enablers and barriers to evidence implementation in CM were eligible for inclusion. Eight databases and search engines were searched for eligible studies. Reference lists of included studies were screened, and authors of included studies were contacted to identify current or unpublished studies that met the inclusion criteria.

Results

Thirty-nine published and unpublished studies were included in this review. The seven published qualitative studies and 25 published quantitative studies were rated as moderate to high quality. Fifty-two distinct barriers and 62 discrete enablers were identified. Reported barriers were predominantly structural (e.g. limited availability of time and clinical evidence) and cognitive (e.g. skills deficits), with relatively fewer studies reporting cultural (e.g. lack of industry support) or attitudinal barriers (e.g. lack of interest in, or relevance to CM). Enablers of evidence implementation largely focussed on improving access to bibliographic databases and evidence reviews, supporting skills acquisition, and cultivating leadership and interprofessional/interagency collaboration.

Conclusions

The findings of this review highlight the diverse barriers and enablers to evidence implementation in CM that span multiple dimensions. The interplay between these various factors highlights the complexity of evidence implementation, and the need for a targeted multistakeholder, multidimensional solution to optimise evidence-based practice in CM.

Study registration

The protocol of this review was registered at PROSPERO (CRD42022308527).

尽管补充医学(CM)从业者参与证据实施的推动,以及支持循证实践(EBP)的争论,但大多数CM专业对EBP的吸收仍然很低。本综述旨在综合证据,检查CM中证据实施的障碍和促成因素。方法任何检查CM证据实施的促成因素和障碍的初步研究都符合纳入条件。在8个数据库和搜索引擎中搜索了符合条件的研究。筛选纳入研究的参考文献,并联系纳入研究的作者,以确定符合纳入标准的当前或未发表的研究。结果本综述纳入39项已发表和未发表的研究。7项已发表的定性研究和25项已发表的定量研究被评为中等至高质量。确定了52个不同的障碍和62个离散的使能因素。报告的障碍主要是结构性障碍(如时间和临床证据有限)和认知障碍(如技能缺陷),报告文化障碍(如缺乏行业支持)或态度障碍(如缺乏兴趣或与CM相关)的研究相对较少。证据实施的推动因素主要侧重于改善书目数据库的获取和证据审查,支持技能获取,培养领导力和专业间/机构间合作。本综述的发现突出了CM中证据实施的各种障碍和推动因素,这些障碍和推动因素跨越多个维度。这些不同因素之间的相互作用突出了证据实施的复杂性,以及需要有针对性的多利益相关者、多维解决方案来优化CM中的循证实践。研究注册本综述的方案在PROSPERO注册(CRD42022308527)。
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引用次数: 4
Artificial intelligence in ophthalmology: A multidisciplinary approach 眼科学中的人工智能:多学科方法
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-12-01 DOI: 10.1016/j.imr.2022.100888
Abhimanyu S. Ahuja , Isabella V. Wagner , Syril Dorairaj , Leticia Checo , Richard Ten Hulzen
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引用次数: 3
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