Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609253
E. Natarajan, Sindhu Suuki, Anitha.
In this study, we report the synthesis of silver nanoparticles (AgNPs) using Azadirachta indica leaf extract and its characterization by UV-Vis spectroscopy, SEM and EDS. The UV-Vis spectral analysis showed a peak around 420nm which is the characteristic λmax of AgNPs. The SEM analysis revealed that AgNPs were largely spherical in shape with average size of 22nm. EDS data indicate that silver was the major component with small amount of gold which was used during processing of sample. The Polyurethane(PU) foam was impregnated with biosynthesized AgNPs and the antibacterial activity against E.coli ATCC 25922 was evaluated by zone of clearance test and tube test. The obtained results indicate the potential of using biosynthesized AgNPs impregnated PU foam as an effective antibacterial water treatment system.
{"title":"Removal of E.coli ATCC 25922 (indicator of fecal contamination) from drinking water by biosynthesized silver nanoparticles impregnated polyurethane foam","authors":"E. Natarajan, Sindhu Suuki, Anitha.","doi":"10.1109/ICANMEET.2013.6609253","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609253","url":null,"abstract":"In this study, we report the synthesis of silver nanoparticles (AgNPs) using Azadirachta indica leaf extract and its characterization by UV-Vis spectroscopy, SEM and EDS. The UV-Vis spectral analysis showed a peak around 420nm which is the characteristic λmax of AgNPs. The SEM analysis revealed that AgNPs were largely spherical in shape with average size of 22nm. EDS data indicate that silver was the major component with small amount of gold which was used during processing of sample. The Polyurethane(PU) foam was impregnated with biosynthesized AgNPs and the antibacterial activity against E.coli ATCC 25922 was evaluated by zone of clearance test and tube test. The obtained results indicate the potential of using biosynthesized AgNPs impregnated PU foam as an effective antibacterial water treatment system.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"82 1","pages":"252-255"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85483895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609359
B. Goswami, A. Choudhury
Cadmium Selenide (CdSe) nanoparticles are synthesized by a simple and cost effective one pot synthesis method and incorporated size selective precipitation to get powder samples. We have studied structural, morphological and optical properties by High resolution transmission electron microscope (HR-TEM), X-ray diffraction (XRD), Uv-vis reflectance spectra and photoluminescence spectra (PL). We have doped CdSe nanoparticles with Manganese (Mn2+) ions and saw the modifications in optical and morphological properties. Band gap and crystallite size of the nanoparticles are quite antiphonal to doping concentration. Calculated Urbach energies and Lattice parameters are also seemed to be changed with dopant concentration due to substitutional doping.
{"title":"Dopant induced changes in optical and structural properties of Cadmium Selenide nanoparticles","authors":"B. Goswami, A. Choudhury","doi":"10.1109/ICANMEET.2013.6609359","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609359","url":null,"abstract":"Cadmium Selenide (CdSe) nanoparticles are synthesized by a simple and cost effective one pot synthesis method and incorporated size selective precipitation to get powder samples. We have studied structural, morphological and optical properties by High resolution transmission electron microscope (HR-TEM), X-ray diffraction (XRD), Uv-vis reflectance spectra and photoluminescence spectra (PL). We have doped CdSe nanoparticles with Manganese (Mn2+) ions and saw the modifications in optical and morphological properties. Band gap and crystallite size of the nanoparticles are quite antiphonal to doping concentration. Calculated Urbach energies and Lattice parameters are also seemed to be changed with dopant concentration due to substitutional doping.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"61 1","pages":"532-535"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80478522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609378
A. Ranjan, Kumar Phanishwar, Ajitesh Ranjan, Md Khalid Hakim
Hydraulic fracturing of rocks is a frequently practiced technique in upstream hydrocarbon industry. However, the phenomena relates to brittle fracture. Fracture formation in visco-elastic materials is a relatively poorly understood process. Inspired by hydraulic fracturing of rocks, fluid fracturing of viscoelastic materials is the proposed technique for the development of micro fractures or pores in a viscoelastic material which is not only simple but effective too. In this method fluid is injected inside the material and at sufficient pressure fractures are observed. In our research, we have found that this method can be used to develop micro fractures of controlled morphology, size and orientation, and thus can have vital applications. Micro fracture development can find a wide range of application including micro filtration, microfluidics, micro reactors, adsorption etc. This paper discusses the basic methodology and the results of experiments conducted on cross-linked polydimethylsiloxane (PDMS), mainly focussing upon the morphology and size variation of fracture depending upon the degree of cross linking and fluid injection pressure.
{"title":"Micro-fracture development in visco-elastic material through fluid fracturing","authors":"A. Ranjan, Kumar Phanishwar, Ajitesh Ranjan, Md Khalid Hakim","doi":"10.1109/ICANMEET.2013.6609378","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609378","url":null,"abstract":"Hydraulic fracturing of rocks is a frequently practiced technique in upstream hydrocarbon industry. However, the phenomena relates to brittle fracture. Fracture formation in visco-elastic materials is a relatively poorly understood process. Inspired by hydraulic fracturing of rocks, fluid fracturing of viscoelastic materials is the proposed technique for the development of micro fractures or pores in a viscoelastic material which is not only simple but effective too. In this method fluid is injected inside the material and at sufficient pressure fractures are observed. In our research, we have found that this method can be used to develop micro fractures of controlled morphology, size and orientation, and thus can have vital applications. Micro fracture development can find a wide range of application including micro filtration, microfluidics, micro reactors, adsorption etc. This paper discusses the basic methodology and the results of experiments conducted on cross-linked polydimethylsiloxane (PDMS), mainly focussing upon the morphology and size variation of fracture depending upon the degree of cross linking and fluid injection pressure.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"84 1","pages":"663-665"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89683315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609377
R. Joselin, D. Sudharsan, R. Robert
Metal Matrix Composites (MMC's) have created a better interest in recent times for various applications. Advance composite materials like AlSiC metal matrix composite is gradually becoming very important materials manufactu ring aerospace, satellite, automotive and automobile Indus tries due to their superior properties such as light weight, low density, high strength to weight ratio,hardness, temperature withstand and thermal shock resistance, superior wear and corrosive resistance, high specific modulus, highfatigue strength etc. In this paper, aluminium Al-6063&SiC are produced reinforced particles metal matrix composites using manual stir casting technique. In the prepared MMCs flats and round cross section rods are prepared with varying reinforced particles bychanging the weight fraction ranging from 5%, 10%, 15%, and 20%of SiC. The stirring process is carried out manually by a graphite stirrer. The prepared specimens are further tested using a On line monitoring technique namely, Acoustic Emission. Further the same specimens were tested in to various conventional mechanical testing via. Impact strength, microstructure test and micro hardnesstest, Finally it is clearly viewed that hardness of the specimen might be increased with an increase of weight fraction of SiC particle. Also it is observed that the tensile strength and impact strength propertiesare increased with addition of weight fraction of SiC reinforced particle. Similarly by varying the particle size and weight fraction of SiC more other mechanical test can be attempted.
{"title":"Determination of mechanical properties in AlSiC specimen using non destructive method","authors":"R. Joselin, D. Sudharsan, R. Robert","doi":"10.1109/ICANMEET.2013.6609377","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609377","url":null,"abstract":"Metal Matrix Composites (MMC's) have created a better interest in recent times for various applications. Advance composite materials like AlSiC metal matrix composite is gradually becoming very important materials manufactu ring aerospace, satellite, automotive and automobile Indus tries due to their superior properties such as light weight, low density, high strength to weight ratio,hardness, temperature withstand and thermal shock resistance, superior wear and corrosive resistance, high specific modulus, highfatigue strength etc. In this paper, aluminium Al-6063&SiC are produced reinforced particles metal matrix composites using manual stir casting technique. In the prepared MMCs flats and round cross section rods are prepared with varying reinforced particles bychanging the weight fraction ranging from 5%, 10%, 15%, and 20%of SiC. The stirring process is carried out manually by a graphite stirrer. The prepared specimens are further tested using a On line monitoring technique namely, Acoustic Emission. Further the same specimens were tested in to various conventional mechanical testing via. Impact strength, microstructure test and micro hardnesstest, Finally it is clearly viewed that hardness of the specimen might be increased with an increase of weight fraction of SiC particle. Also it is observed that the tensile strength and impact strength propertiesare increased with addition of weight fraction of SiC reinforced particle. Similarly by varying the particle size and weight fraction of SiC more other mechanical test can be attempted.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"69 1","pages":"658-662"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74493652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609323
B. Mondal, S. Hungyo, C. Roychaudhury, H. Saha
We report on the fabrication of Zinc Oxide (ZnO) nanorod based H2 sensor using a simple chemical route. ZnO films were deposited on Si substrate followed by annealing and used to detect hydrogen. The surface morphology and crystal structure of the fabricated ZnO system was investigated by scanning electron microscopy (SEM) and X-ray diffraction (XRD). The gas sensing of H2 in the concentration range 0.1-1 vol % in dry air was studied using current-voltage measurements. Gas sensing mechanism is discussed.
{"title":"ZnO nano-rod based hydrogen sensor","authors":"B. Mondal, S. Hungyo, C. Roychaudhury, H. Saha","doi":"10.1109/ICANMEET.2013.6609323","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609323","url":null,"abstract":"We report on the fabrication of Zinc Oxide (ZnO) nanorod based H2 sensor using a simple chemical route. ZnO films were deposited on Si substrate followed by annealing and used to detect hydrogen. The surface morphology and crystal structure of the fabricated ZnO system was investigated by scanning electron microscopy (SEM) and X-ray diffraction (XRD). The gas sensing of H2 in the concentration range 0.1-1 vol % in dry air was studied using current-voltage measurements. Gas sensing mechanism is discussed.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"6 1","pages":"376-378"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74825279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609273
R. Naresh Kumar, Balaji Padya, S. Chandrasekhar, P. K. Jain, V. Srikanth, K. BhanuSankaraRao
Multiwall Carbon Nanotubes (MWCNTs)/Copper (Cu) nanocomposites with different loadings of MWCNTs have been fabricated by conventional sintering. Morphological, structural and phase characteristics of thesenanocomposites have been studied.
{"title":"Morphological, structural and phase characteristics of conventionally sintered MWCNTs/Cu composite","authors":"R. Naresh Kumar, Balaji Padya, S. Chandrasekhar, P. K. Jain, V. Srikanth, K. BhanuSankaraRao","doi":"10.1109/ICANMEET.2013.6609273","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609273","url":null,"abstract":"Multiwall Carbon Nanotubes (MWCNTs)/Copper (Cu) nanocomposites with different loadings of MWCNTs have been fabricated by conventional sintering. Morphological, structural and phase characteristics of thesenanocomposites have been studied.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"53 3 1","pages":"190-192"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79717945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609320
S. K. Kumar, K. Kavyashree, B. Pallavi, S. Kiran, N. S. Kumar, P. Sharanappa
Nanomaterials have been found to exhibit interesting properties like semiconducting, piezoelectricity etc. Among all metal oxides nanoparticles, particularly Zinc Oxide has become a material of interest among scientific community, due to the commercial importance. Zinc Oxide materials are biocompatible, chemically stable, nontoxic, electrochemically active and have fast electron transfer rate. In the present work a method of fabricating glucose sensor is described. ZnO nanoparticles are synthesized using wet chemical method. The synthesized nanoparticles are dip coated onto a silicon substrate. Enzyme immobilization is done on the nanoparticles by keeping the thin film in 4°C for 24 hrs. Optical and structural characterization of the synthesized sample is studied. The result of UV spectrometer reveals the formation of ZnO nanoparticles by showing absorption peak at 376.27 nm. The XRD pattern taken for the ZnO nanoparticles showed that the average particle size is to be 21.6 nm. SEM image of the sample is taken by depositing on the silicon wafer. Finally sensing property of sensor is examined by establishing contacts. The studies showed that the sensor has a linear response to the change in glucose concentration.
{"title":"Fabrication and characterization of enzymatic glucose sensor based on ZnO nanoparticles","authors":"S. K. Kumar, K. Kavyashree, B. Pallavi, S. Kiran, N. S. Kumar, P. Sharanappa","doi":"10.1109/ICANMEET.2013.6609320","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609320","url":null,"abstract":"Nanomaterials have been found to exhibit interesting properties like semiconducting, piezoelectricity etc. Among all metal oxides nanoparticles, particularly Zinc Oxide has become a material of interest among scientific community, due to the commercial importance. Zinc Oxide materials are biocompatible, chemically stable, nontoxic, electrochemically active and have fast electron transfer rate. In the present work a method of fabricating glucose sensor is described. ZnO nanoparticles are synthesized using wet chemical method. The synthesized nanoparticles are dip coated onto a silicon substrate. Enzyme immobilization is done on the nanoparticles by keeping the thin film in 4°C for 24 hrs. Optical and structural characterization of the synthesized sample is studied. The result of UV spectrometer reveals the formation of ZnO nanoparticles by showing absorption peak at 376.27 nm. The XRD pattern taken for the ZnO nanoparticles showed that the average particle size is to be 21.6 nm. SEM image of the sample is taken by depositing on the silicon wafer. Finally sensing property of sensor is examined by establishing contacts. The studies showed that the sensor has a linear response to the change in glucose concentration.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"108 1","pages":"363-366"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75623817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609259
V. Bansal, Manu Dalela, Manoj Kumar, H. Brahmne, Harpal Singh
At present choice of adjuvants for human vaccination reflects a compromise between a requirement for adjuvanticity and an acceptable level of side-effects. To overcome the side effects, encapsulation of antigen in the biodegradable polymeric nanoparticles (NPs) may be a promising approach, which may be developed as adjuvants. Moreover, small size of these nano-formulations may help to project the antigen directly to the antigen presenting cells (APCs) for stimulating cell mediate immunity. The present study was directed towards the evaluation of PLA and PCL based nanoformulations as potential adjuvants by using tetanus toxoid as model antigen. The particles size was observed in the range from 92.9 ± 2.6 to 124.6 ± 3.7 nm having zeta potential of -12.4 ± 1.2 to -3.4 ± 1.5. The loading efficiency of different formulations ranges from 46.3 - 56.8 %. Highest loading of 56.8% and burst release (82 % in 48 days) was observed in PLA-PEG based nanoformulation. In terms of anti-tetanus antibodies (determined by ELISA) titer of > 0.5 IU/ml was observed upto 70 days in all the survived mice. Efficacy of nanoformulations was studied in mice by challenge method over different time intervals wherein tetanus loaded PLA, PLA-PEG and PCL NPs shows maximum efficacy at 28, 56 and 21 days respectively. The study shows that the biodegradable nanoparticle based formulations has no toxicity, comparable efficacy and therefore has a strong potential as vaccine adjuvant and delivery system.
{"title":"Evaluation of effectiveness of polymeric nanoparticles based vaccine delivery system over varying time intervals using tetanus toxoid as model antigen","authors":"V. Bansal, Manu Dalela, Manoj Kumar, H. Brahmne, Harpal Singh","doi":"10.1109/ICANMEET.2013.6609259","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609259","url":null,"abstract":"At present choice of adjuvants for human vaccination reflects a compromise between a requirement for adjuvanticity and an acceptable level of side-effects. To overcome the side effects, encapsulation of antigen in the biodegradable polymeric nanoparticles (NPs) may be a promising approach, which may be developed as adjuvants. Moreover, small size of these nano-formulations may help to project the antigen directly to the antigen presenting cells (APCs) for stimulating cell mediate immunity. The present study was directed towards the evaluation of PLA and PCL based nanoformulations as potential adjuvants by using tetanus toxoid as model antigen. The particles size was observed in the range from 92.9 ± 2.6 to 124.6 ± 3.7 nm having zeta potential of -12.4 ± 1.2 to -3.4 ± 1.5. The loading efficiency of different formulations ranges from 46.3 - 56.8 %. Highest loading of 56.8% and burst release (82 % in 48 days) was observed in PLA-PEG based nanoformulation. In terms of anti-tetanus antibodies (determined by ELISA) titer of > 0.5 IU/ml was observed upto 70 days in all the survived mice. Efficacy of nanoformulations was studied in mice by challenge method over different time intervals wherein tetanus loaded PLA, PLA-PEG and PCL NPs shows maximum efficacy at 28, 56 and 21 days respectively. The study shows that the biodegradable nanoparticle based formulations has no toxicity, comparable efficacy and therefore has a strong potential as vaccine adjuvant and delivery system.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"96 1","pages":"137-139"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75935730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609219
V. Ganesan, A. Deepak
In this paper we are reporting the different methods of synthesis and characterization of gold colloid, silver colloid and Multiwall carbon nanotube based composites and the potential applications. Three types of gold colloids (negative, neutral, positive) were produced by chemical reduction of uric chloride using either sodium citrate or sodium borohydride or diethyl amino pyridine (DMAP) as reducing agents. Silver colloid was produced by reduction of silver nitrate solution. Multiwall Carbon Nanotubes (MWCNT's) based composites are synthesized using solvent casting method. The formation of Au and Ag nanoparticles was confirmed by the appearance of surface Plasmon absorption maxima at 560 and 420 nm for Au and Ag nanoparticles respectively using UV-Visible spectroscopy. All these nano materials and MWCNT based composites are characterized using SEM, TEM, AFM and XRD. XRD analysis of gold and silver colloids revealed all relevant Bragg's reflections corresponding to the FCC crystal structure as given in the JCPDS data for gold and silver colloid. However some new peaks which do not belong to the above structure were also present in the data for both Au and Ag. In this paper we are also reporting the possibility of using Polyvinylidene Fluoride (PVDF)/CNT composite as strain sensors. Different weight percentage (2 Wt%, 3 Wt%, 4 Wt %) of CNT-PVDF polymer nanocomposite films are prepared and they are characterized using various techniques and reported. The strain and defect measurements using the CNT-PVDF nanocomposite as a novel Non-destructive technique (NDT) is briefly explained.
{"title":"Synthesis, characterization and applications of some nanomaterials","authors":"V. Ganesan, A. Deepak","doi":"10.1109/ICANMEET.2013.6609219","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609219","url":null,"abstract":"In this paper we are reporting the different methods of synthesis and characterization of gold colloid, silver colloid and Multiwall carbon nanotube based composites and the potential applications. Three types of gold colloids (negative, neutral, positive) were produced by chemical reduction of uric chloride using either sodium citrate or sodium borohydride or diethyl amino pyridine (DMAP) as reducing agents. Silver colloid was produced by reduction of silver nitrate solution. Multiwall Carbon Nanotubes (MWCNT's) based composites are synthesized using solvent casting method. The formation of Au and Ag nanoparticles was confirmed by the appearance of surface Plasmon absorption maxima at 560 and 420 nm for Au and Ag nanoparticles respectively using UV-Visible spectroscopy. All these nano materials and MWCNT based composites are characterized using SEM, TEM, AFM and XRD. XRD analysis of gold and silver colloids revealed all relevant Bragg's reflections corresponding to the FCC crystal structure as given in the JCPDS data for gold and silver colloid. However some new peaks which do not belong to the above structure were also present in the data for both Au and Ag. In this paper we are also reporting the possibility of using Polyvinylidene Fluoride (PVDF)/CNT composite as strain sensors. Different weight percentage (2 Wt%, 3 Wt%, 4 Wt %) of CNT-PVDF polymer nanocomposite films are prepared and they are characterized using various techniques and reported. The strain and defect measurements using the CNT-PVDF nanocomposite as a novel Non-destructive technique (NDT) is briefly explained.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"105 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80714643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609393
D. Bennet, Sanghyo Kim
Various bioactive molecules help to cure skin diseases from solar radiation. Exploring the cellular behavior and real-time estimation of photo-oxidative stress in skin cells require advanced sensitive methods. In our present research describes an analytical tool, which unprecedented, simple and real-time in vitro light setup was established using a bioimpedance system to measure the skin cell photo-oxidative damage and protective effect of drugs. In order to overcome the stability of drugs, biodegradable permeation enhanced poly(D,L-lactide-coglycolide) (PLGA) nanoparticles (NPs) had been used to improve the therapeutic efficacy. Quercetin-loaded PLGA NPs were synthesized. Structural characterization confirmed a spherical mono-dispersed particle size distribution of 96 nm. In the present study, investigated photo-oxidative stress damage and addressed the HDFn cell behavior using continuous measurement of electrical cell-substrate impedance sensing technique, and compared with standard viability assay. Also photo-protective effects of prepared quercetin-loaded NPs and raw drugs were examined by real-time manner. The produced NPs shows high encapsulation efficiency, less toxicity, enhanced cellular uptake. Also the NPs shows high photo-protective effect on HDFn cells through scavenging of free radicals, and it can shows their better action to target sites. The proposed system identifies the phototoxic effects in skin cells and provides high throughput drug screening during early stages of photo-oxidative stress, and would be of broad interest in the field of therapeutics.
各种生物活性分子有助于治疗太阳辐射引起的皮肤病。探索细胞行为和实时估计皮肤细胞的光氧化应激需要先进的敏感方法。本研究利用生物阻抗系统，建立了一种前所未有的、简单的、实时的体外光装置来测量皮肤细胞的光氧化损伤和药物的保护作用。为了克服药物的稳定性，采用可生物降解的渗透增强聚(D, l -丙交酯-乙醇酸酯)(PLGA)纳米颗粒(NPs)来提高治疗效果。合成了负载槲皮素的PLGA NPs。结构表征证实了96 nm的球形单分散粒度分布。在本研究中，研究了光氧化应激损伤和HDFn细胞的行为，使用连续测量的电-基质阻抗传感技术，并与标准的活力测定进行了比较。实时检测槲皮素负载NPs和原料药的光保护作用。制备的NPs包封效率高，毒性小，细胞摄取增强。NPs通过清除自由基对hdf细胞表现出较高的光保护作用，对靶部位具有较好的作用。该系统可识别皮肤细胞中的光毒性作用，并在光氧化应激的早期阶段提供高通量药物筛选，将在治疗学领域引起广泛关注。
{"title":"ECIS to assess human skin cell photo-oxidative damage","authors":"D. Bennet, Sanghyo Kim","doi":"10.1109/ICANMEET.2013.6609393","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609393","url":null,"abstract":"Various bioactive molecules help to cure skin diseases from solar radiation. Exploring the cellular behavior and real-time estimation of photo-oxidative stress in skin cells require advanced sensitive methods. In our present research describes an analytical tool, which unprecedented, simple and real-time in vitro light setup was established using a bioimpedance system to measure the skin cell photo-oxidative damage and protective effect of drugs. In order to overcome the stability of drugs, biodegradable permeation enhanced poly(D,L-lactide-coglycolide) (PLGA) nanoparticles (NPs) had been used to improve the therapeutic efficacy. Quercetin-loaded PLGA NPs were synthesized. Structural characterization confirmed a spherical mono-dispersed particle size distribution of 96 nm. In the present study, investigated photo-oxidative stress damage and addressed the HDFn cell behavior using continuous measurement of electrical cell-substrate impedance sensing technique, and compared with standard viability assay. Also photo-protective effects of prepared quercetin-loaded NPs and raw drugs were examined by real-time manner. The produced NPs shows high encapsulation efficiency, less toxicity, enhanced cellular uptake. Also the NPs shows high photo-protective effect on HDFn cells through scavenging of free radicals, and it can shows their better action to target sites. The proposed system identifies the phototoxic effects in skin cells and provides high throughput drug screening during early stages of photo-oxidative stress, and would be of broad interest in the field of therapeutics.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"24 1","pages":"696-701"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75496122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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