Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609298
Sumali Bansal, Priyanka, R. Bhandari, K. Dharamvir
Under tensile deformation at 0K, gold nanowires progressively thin through a series of metastable ordered structures such as closed structure bond formations, kinks, Zig - Zag chain, straightening of the chain and then finally leading to its breaking at various stages of stretching possessing both structural and mechanical stabilities. Using atomistic simulations, we study the impact of stretching on the structural evolution of Monatomic gold nanochains (MACs) undergoing elongation along with its application in Tubular gold structure using SIESTA (Spanish Initiative for Electronic Simulation with Thousands of Atoms), the computational code based on Density Functional theory method. In particular, our simulations result in a large number of monatomic chains and intermediate structures.
在0K的拉伸变形下，金纳米线通过一系列亚稳态有序结构，如闭合结构键形成、扭结、之字形链、链的拉直，最终导致其在拉伸的各个阶段断裂，从而逐渐变细，具有结构和机械稳定性。本文利用SIESTA (Spanish Initiative for Electronic Simulation with thousand Atoms)基于密度泛函理论方法的计算程序，研究了拉伸对单原子金纳米链(MACs)结构演化的影响及其在管状金结构中的应用。特别是，我们的模拟得到了大量的单原子链和中间结构。
{"title":"Monatomic Gold Nanochains and their encapsulation in Au60Au9 tubular structure","authors":"Sumali Bansal, Priyanka, R. Bhandari, K. Dharamvir","doi":"10.1109/ICANMEET.2013.6609298","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609298","url":null,"abstract":"Under tensile deformation at 0K, gold nanowires progressively thin through a series of metastable ordered structures such as closed structure bond formations, kinks, Zig - Zag chain, straightening of the chain and then finally leading to its breaking at various stages of stretching possessing both structural and mechanical stabilities. Using atomistic simulations, we study the impact of stretching on the structural evolution of Monatomic gold nanochains (MACs) undergoing elongation along with its application in Tubular gold structure using SIESTA (Spanish Initiative for Electronic Simulation with Thousands of Atoms), the computational code based on Density Functional theory method. In particular, our simulations result in a large number of monatomic chains and intermediate structures.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"9 1","pages":"305-308"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90711144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609274
Prabin Pradhan, V. Muthukumar, Muralikrishna Molli, S. Srivastava, S. Sai, S. Mitra
We report here the nonlinear optical response of Solubilized Multiwalled Carbon Nanotubes (MWNTs) and these decorated with Platinum and Palladium Nanoparticles. Pristine MWNTs were functionalized with COOH group through microwave assisted synthesis route which rendered them soluble in water and other solvents too. Metal salts of Platinum and Palladium were further reduced to metal nanoparticles in presence of MWNT-COOH under microwave irradiation. These hybrid metal decorated carbon nanostructures were morphologically and functionally well characterized using SEM, EDAX, FTIR, UV-Visible etc., Using Z-scan technique, we carried out nonlinear optical studies on aqueous dispersions (stable) of these metal decorated (Pt/Pd-MWNT-COOH) using a high power Nd:YAG Laser with 532 nm excitation with 10 nanosecond pulse width. These samples exhibited significant nonlinear absorption and scattering. The metal decorated MWNT-COOH (Pt-MWNT-COOH:2 Jcm-2; Pd-MWNT-COOH: 1.7Jcm-2) exhibited enhanced optical limiting which is more than plain MWNT-COOH samples and similar Metal-Graphene hybrid dispersions reported earlier in literature. These could be ideally suited for optical power limiting applications.
{"title":"Enhanced optical limiting of solubilized carbon nanotubesdecorated with Pt/Pd nanoparticles","authors":"Prabin Pradhan, V. Muthukumar, Muralikrishna Molli, S. Srivastava, S. Sai, S. Mitra","doi":"10.1109/ICANMEET.2013.6609274","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609274","url":null,"abstract":"We report here the nonlinear optical response of Solubilized Multiwalled Carbon Nanotubes (MWNTs) and these decorated with Platinum and Palladium Nanoparticles. Pristine MWNTs were functionalized with COOH group through microwave assisted synthesis route which rendered them soluble in water and other solvents too. Metal salts of Platinum and Palladium were further reduced to metal nanoparticles in presence of MWNT-COOH under microwave irradiation. These hybrid metal decorated carbon nanostructures were morphologically and functionally well characterized using SEM, EDAX, FTIR, UV-Visible etc., Using Z-scan technique, we carried out nonlinear optical studies on aqueous dispersions (stable) of these metal decorated (Pt/Pd-MWNT-COOH) using a high power Nd:YAG Laser with 532 nm excitation with 10 nanosecond pulse width. These samples exhibited significant nonlinear absorption and scattering. The metal decorated MWNT-COOH (Pt-MWNT-COOH:2 Jcm-2; Pd-MWNT-COOH: 1.7Jcm-2) exhibited enhanced optical limiting which is more than plain MWNT-COOH samples and similar Metal-Graphene hybrid dispersions reported earlier in literature. These could be ideally suited for optical power limiting applications.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"16 1","pages":"193-196"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91141589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609264
P. Vanga, M. Ashok
Fe and Co co-doped ZnO nanoparticles were synthesized by hydrothermal method. Limit of substitution was identified using XRD. Magnetic measurements at room temperature for doped samples showed paramagnetic and ferromagnetic in nature. The reflectance spectra exhibited the absorption peaks corresponding to both dopant and host ions. Emission spectra show defect related peaks, suppression of visible spectra peaks is observed in doped samples.
{"title":"Magnetic and optical studies of Fe and Co co-doped ZnO","authors":"P. Vanga, M. Ashok","doi":"10.1109/ICANMEET.2013.6609264","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609264","url":null,"abstract":"Fe and Co co-doped ZnO nanoparticles were synthesized by hydrothermal method. Limit of substitution was identified using XRD. Magnetic measurements at room temperature for doped samples showed paramagnetic and ferromagnetic in nature. The reflectance spectra exhibited the absorption peaks corresponding to both dopant and host ions. Emission spectra show defect related peaks, suppression of visible spectra peaks is observed in doped samples.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"33 1","pages":"154-156"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88728984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609241
P. Yuvasree, K. Nithya, N. Neelakandeswari
Aloe vera is a stem less or very shortstemmed succulent plant growing to 60-100 cm (24-39 in) tall, spreading by offsets. The leaves are thick and fleshy, green to grey-green, with some varieties showing white flecks on the upper and lower stem surfaces. In recent years, researchers in the field of nanotechnology are finding that metal nanoparticles have all kinds of previously unexpected benefits.A new branch of nanotechnology is nanobiotechnology. Nanobiotechnology represents an economic alternative for chemical and physical methods of nanoparticles formation. When compare to physical and chemical methods biological methods have emerged as an alternative to the conventional methods for synthesis of NPs. Synthesis of inorganic nanoparticles by biological systems makes nanoparticles more biocompatible and environmentally benign. Many bacterial as well as fungal species have been used for silver nanoparticles synthesis. But most of them have been reported to accumulate silver nanoparticles intracellularly. Intracellular synthesis always takes longer reaction times and also demands subsequent extraction and recovery steps. On the contrary, plant extract mediated synthesis always takes place extracellularly, and the reaction times have also been reported to be very short compared to that of microbial synthesis. In the present study young fresh plant stems were collected and the inner green flesh was used for the synthesis of silver nanoparticles. 20 mL of aqueous extract was added to 20 mL of 1mM silver nitrate solution. The solution was allowed to react at room temperature and incubated in dark condition. After 24hrs the color change was observed and the extract was subjected to UV - Visible studies. Though the plasmon band is broad due to the presence of components in extract which are also being read in the spectrophotometric range, it is observed that the silver surface plasmon resonance (SPR) occurs at 460nm. Here is no change in peak position, suggesting that nucleation of silver nanoparticles starts with initiation of reaction time only, and the size remains unchanged throughout the course of reaction. The antibacterial activity was conducted against E.coli, and Bacillus Species. Bioreduced silver nanoparticles showed considerable growth inhibition of two of the well-known pathogenic bacteria species. Zones of 11 mm and 10 mm were observed for E. coli and Bacillus Species respectively.
芦荟是一种茎少或茎短的多肉植物，生长到60-100厘米(24-39英寸)高，通过offset展开。叶子厚而肉质，绿色到灰绿色，一些品种在茎的上下表面显示白色斑点。近年来，纳米技术领域的研究人员发现，金属纳米颗粒具有各种以前意想不到的优点。纳米技术的一个新分支是纳米生物技术。纳米生物技术代表了化学和物理方法形成纳米颗粒的经济替代方案。与物理和化学方法相比，生物方法已成为合成NPs的传统方法的替代方法。生物系统合成无机纳米粒子使纳米粒子更具生物相容性和环境友好性。许多细菌和真菌物种已被用于银纳米颗粒的合成。但据报道，它们中的大多数在细胞内积聚银纳米粒子。细胞内合成总是需要较长的反应时间，也需要随后的提取和回收步骤。相反，植物提取物介导的合成总是发生在细胞外，与微生物合成相比，反应时间也很短。在本研究中，我们收集了新鲜的植物幼嫩茎，并利用其内部的绿色果肉来合成纳米银。将20 mL水提取物加入20 mL 1mM硝酸银溶液中。溶液在室温下反应，在黑暗条件下孵育。24h后观察颜色变化，并进行紫外可见研究。虽然由于萃取物中存在的组分也在分光光度范围内被读取，等离子体带很宽，但观察到银表面等离子体共振(SPR)发生在460nm处。这里峰的位置没有变化，说明银纳米粒子的成核只从反应时间开始，在整个反应过程中尺寸保持不变。对大肠杆菌和芽孢杆菌进行了抑菌试验。生物还原银纳米颗粒对两种众所周知的致病菌显示出相当大的生长抑制作用。大肠杆菌和芽孢杆菌分别为11 mm和10 mm。
{"title":"Biosynthesis of silver nanoparticles from Aloe vera plant extract and its antimicrobial activity against multidrug resistant pathogens","authors":"P. Yuvasree, K. Nithya, N. Neelakandeswari","doi":"10.1109/ICANMEET.2013.6609241","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609241","url":null,"abstract":"Aloe vera is a stem less or very shortstemmed succulent plant growing to 60-100 cm (24-39 in) tall, spreading by offsets. The leaves are thick and fleshy, green to grey-green, with some varieties showing white flecks on the upper and lower stem surfaces. In recent years, researchers in the field of nanotechnology are finding that metal nanoparticles have all kinds of previously unexpected benefits.A new branch of nanotechnology is nanobiotechnology. Nanobiotechnology represents an economic alternative for chemical and physical methods of nanoparticles formation. When compare to physical and chemical methods biological methods have emerged as an alternative to the conventional methods for synthesis of NPs. Synthesis of inorganic nanoparticles by biological systems makes nanoparticles more biocompatible and environmentally benign. Many bacterial as well as fungal species have been used for silver nanoparticles synthesis. But most of them have been reported to accumulate silver nanoparticles intracellularly. Intracellular synthesis always takes longer reaction times and also demands subsequent extraction and recovery steps. On the contrary, plant extract mediated synthesis always takes place extracellularly, and the reaction times have also been reported to be very short compared to that of microbial synthesis. In the present study young fresh plant stems were collected and the inner green flesh was used for the synthesis of silver nanoparticles. 20 mL of aqueous extract was added to 20 mL of 1mM silver nitrate solution. The solution was allowed to react at room temperature and incubated in dark condition. After 24hrs the color change was observed and the extract was subjected to UV - Visible studies. Though the plasmon band is broad due to the presence of components in extract which are also being read in the spectrophotometric range, it is observed that the silver surface plasmon resonance (SPR) occurs at 460nm. Here is no change in peak position, suggesting that nucleation of silver nanoparticles starts with initiation of reaction time only, and the size remains unchanged throughout the course of reaction. The antibacterial activity was conducted against E.coli, and Bacillus Species. Bioreduced silver nanoparticles showed considerable growth inhibition of two of the well-known pathogenic bacteria species. Zones of 11 mm and 10 mm were observed for E. coli and Bacillus Species respectively.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"2012 1","pages":"84-86"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86408052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609376
Greeni Navin, T. Basavaraj
As the world is on lookout for the smarter and faster and energy efficient technology, CNTFETs are considered as one of the emerging elements of nanotechnology for future logic applications, with high figures for mobility, achievable current density thereby creating high performance systems on chip with lower cost. CNTFETs are promising devices but what makes it difficult to model a CNT is that nanotubes have a very broad range of electronic, thermal, and structural properties that change depending on parameters defined by its diameter, length, gate parameters and chirality or twist. In this paper various device parameters are discussed which can affect the switching and storing of data in the CNTFET memory cells. Hysteresis was clearly observed in the curve of the drain current versus gate voltage, which makes the CNTFET possible for a nonvolatile memory cell. In this paper the various parameters which can affect the performance of CNT as memory cell has been discussed.
{"title":"Factors affecting performance of CNT FET as a switch in memory cell","authors":"Greeni Navin, T. Basavaraj","doi":"10.1109/ICANMEET.2013.6609376","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609376","url":null,"abstract":"As the world is on lookout for the smarter and faster and energy efficient technology, CNTFETs are considered as one of the emerging elements of nanotechnology for future logic applications, with high figures for mobility, achievable current density thereby creating high performance systems on chip with lower cost. CNTFETs are promising devices but what makes it difficult to model a CNT is that nanotubes have a very broad range of electronic, thermal, and structural properties that change depending on parameters defined by its diameter, length, gate parameters and chirality or twist. In this paper various device parameters are discussed which can affect the switching and storing of data in the CNTFET memory cells. Hysteresis was clearly observed in the curve of the drain current versus gate voltage, which makes the CNTFET possible for a nonvolatile memory cell. In this paper the various parameters which can affect the performance of CNT as memory cell has been discussed.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"24 1","pages":"655-657"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85627101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609311
T. Shyju, R. Gopalakrishnan
Nanocrystalline lead sulphide (PbS) thin films were deposited on glass and ITO coated glass substrates by photochemical method. To improve the adhesive nature and properties the films were deposited on ITO coated substrate using photochemical deposition. The deposited films were characterized to study their structural, morphological and electrical properties. The photochemically deposited PbS thin films possess tetragonal system. The dislocation densities of the deposited thin films were evaluated from the X-ray diffraction data. High Resolution Scanning Electron Micrographs of the deposited film shows the oval shape arrangement of particles. The elemental composition of the film was confirmed by Energy Dispersive X-ray analysis. Hall measurements were carried out for the films and their electrical parameters were evaluated. The as-deposited PbS films have positive Hall coefficient, which confirms p-type conductivity.
{"title":"Studies on lead sulphide thin films deposited by photochemical method","authors":"T. Shyju, R. Gopalakrishnan","doi":"10.1109/ICANMEET.2013.6609311","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609311","url":null,"abstract":"Nanocrystalline lead sulphide (PbS) thin films were deposited on glass and ITO coated glass substrates by photochemical method. To improve the adhesive nature and properties the films were deposited on ITO coated substrate using photochemical deposition. The deposited films were characterized to study their structural, morphological and electrical properties. The photochemically deposited PbS thin films possess tetragonal system. The dislocation densities of the deposited thin films were evaluated from the X-ray diffraction data. High Resolution Scanning Electron Micrographs of the deposited film shows the oval shape arrangement of particles. The elemental composition of the film was confirmed by Energy Dispersive X-ray analysis. Hall measurements were carried out for the films and their electrical parameters were evaluated. The as-deposited PbS films have positive Hall coefficient, which confirms p-type conductivity.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"102 1","pages":"340-343"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80563303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609322
J. P. Devadhasan, Sanghyo Kim
Complementary metal oxide semiconductor (CMOS) technology has an emerging filed in molecular diagnostics and other biological applications. The present study demonstrated that CMOS image sensor based glucose monitoring in mouse plasma by simple photon number changes. The photon number varied in the basis of color differences of oxidized glucose in polydimethylsiloxane (PDMS) chip. The high concentration of glucose produces more color and was allowed to pass less number of photons; the photon numbers are gradually increased with less concentration of glucose. Number of photons are depends on the density of color in mouse glucose. The photons are captured and converted as a digital numbers. The UV-spectral study helps to confirmed that the CMOS image sensor is a precise detection system for glucose measurement by point-of-care approach.
{"title":"CMOS image sensor for measurement of glucose in mouse plasma","authors":"J. P. Devadhasan, Sanghyo Kim","doi":"10.1109/ICANMEET.2013.6609322","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609322","url":null,"abstract":"Complementary metal oxide semiconductor (CMOS) technology has an emerging filed in molecular diagnostics and other biological applications. The present study demonstrated that CMOS image sensor based glucose monitoring in mouse plasma by simple photon number changes. The photon number varied in the basis of color differences of oxidized glucose in polydimethylsiloxane (PDMS) chip. The high concentration of glucose produces more color and was allowed to pass less number of photons; the photon numbers are gradually increased with less concentration of glucose. Number of photons are depends on the density of color in mouse glucose. The photons are captured and converted as a digital numbers. The UV-spectral study helps to confirmed that the CMOS image sensor is a precise detection system for glucose measurement by point-of-care approach.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"18 1","pages":"371-375"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83661574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609258
G. Apoorva, K. Lavanya, Vidisha, Pavani, R. R. Kumar, Q. Hasan, D. Ramakrishna
We investigated the genotoxic effects of 10-20 nm silver (Ag) and Titanium dioxide (TiO2) nanoparticles (NPs) by evaluating chromosome aberrations and polyploidy status and micronucleus (MN) assay. Methods Before testing, we confirmed that the Ag-NPs were completely dispersed in the experimental medium by sonication (three times in 1 minute) and filtration (0.2 μm pore size filter), and then we measured their size in a zeta potential analyzer. After that the genotoxicity was measured. Results After incubation with the defined concentration and size of the Silver and TiO2 nanoparticles, 100 metaphases were analyzed under microscope, 9%, 12% structural aberrations and 3%, 2% numerical aberrations were observed respectively. There was no aberration found in the control sample. After incubation with the defined concentration and size of the Ag & TiO2 nanoparticles, 1000 bi-nucleated cells were analyzed under microscope, 3% and 1% of these cells were observed with micronuclei respectively.Conclusions All of our findings indicate that Ag-and TiO2 NPs show genotoxic effects in mammalian cell system. In addition, present study suggests that the genotoxicity effect of Ag and TiO2 nanoparticles is concentration and size dependent.
{"title":"Genotoxic effects of silver and Titanium dioxide nanoparticles","authors":"G. Apoorva, K. Lavanya, Vidisha, Pavani, R. R. Kumar, Q. Hasan, D. Ramakrishna","doi":"10.1109/ICANMEET.2013.6609258","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609258","url":null,"abstract":"We investigated the genotoxic effects of 10-20 nm silver (Ag) and Titanium dioxide (TiO2) nanoparticles (NPs) by evaluating chromosome aberrations and polyploidy status and micronucleus (MN) assay. Methods Before testing, we confirmed that the Ag-NPs were completely dispersed in the experimental medium by sonication (three times in 1 minute) and filtration (0.2 μm pore size filter), and then we measured their size in a zeta potential analyzer. After that the genotoxicity was measured. Results After incubation with the defined concentration and size of the Silver and TiO2 nanoparticles, 100 metaphases were analyzed under microscope, 9%, 12% structural aberrations and 3%, 2% numerical aberrations were observed respectively. There was no aberration found in the control sample. After incubation with the defined concentration and size of the Ag & TiO2 nanoparticles, 1000 bi-nucleated cells were analyzed under microscope, 3% and 1% of these cells were observed with micronuclei respectively.Conclusions All of our findings indicate that Ag-and TiO2 NPs show genotoxic effects in mammalian cell system. In addition, present study suggests that the genotoxicity effect of Ag and TiO2 nanoparticles is concentration and size dependent.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"13 1","pages":"133-136"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90090790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609290
S. Chauhan, M. Kumar, S. Chhoker, S. C. Katyal
Ba and Mn doped BiFeO3 nanoparticles were synthesized by sol-gel method. X-ray diffraction and Raman spectroscopy results showed the presence of distorted rhombohedral structure for Bi0.85Ba0.15FeO3 nanoparticles and the substitution induced phase transition (rhombohedral to orthorhombic) phase for Bi0.85Mn0.15FeO3 nanoparticles. FESEM images of both the samples revealed grain size in the range from 50 to 100 nm. Magnetic measurement showed room temperature ferromagnetic behavior, which may be attributed to the antiferromagnetic core and the ferromagnetic surface of the nanoparticles, together with the structural distortion caused by Ba and Mn substitution in BiFeO3 samples. The magnetoelectric coupling was evidenced by the observation of the dielectric anomaly in the dielectric constant near antiferromagnetic Neel temperature in both the samples.
{"title":"Structural, raman, dielectric, magnetic and magnetoelectric properties of Ba and Mn doped BiFeO3 nanoparticles","authors":"S. Chauhan, M. Kumar, S. Chhoker, S. C. Katyal","doi":"10.1109/ICANMEET.2013.6609290","DOIUrl":"https://doi.org/10.1109/ICANMEET.2013.6609290","url":null,"abstract":"Ba and Mn doped BiFeO3 nanoparticles were synthesized by sol-gel method. X-ray diffraction and Raman spectroscopy results showed the presence of distorted rhombohedral structure for Bi0.85Ba0.15FeO3 nanoparticles and the substitution induced phase transition (rhombohedral to orthorhombic) phase for Bi0.85Mn0.15FeO3 nanoparticles. FESEM images of both the samples revealed grain size in the range from 50 to 100 nm. Magnetic measurement showed room temperature ferromagnetic behavior, which may be attributed to the antiferromagnetic core and the ferromagnetic surface of the nanoparticles, together with the structural distortion caused by Ba and Mn substitution in BiFeO3 samples. The magnetoelectric coupling was evidenced by the observation of the dielectric anomaly in the dielectric constant near antiferromagnetic Neel temperature in both the samples.","PeriodicalId":13708,"journal":{"name":"International Conference on Advanced Nanomaterials & Emerging Engineering Technologies","volume":"17 1","pages":"275-278"},"PeriodicalIF":0.0,"publicationDate":"2013-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90312597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-07-24DOI: 10.1109/ICANMEET.2013.6609263
N. Kulkarni, S. Dhole, N. Ranpise
Bioavailability of a drug depends upon the solubility of the drug in gastrointestinal environment; most of the new chemical entities coming out through synthesis are of low solubility (less than 1 mg/ml). The oral bioavailability of Rosuvastatin calcium is less, it may be due to its low water solubility. The objective of the study is to improve solubility of Rosuvastatin Calcium by development of liquid self micro-emulsifying dosage form development. The solubility of Rosuvastatin Calcium is determined in different oils (Sefsol 228, IAS, Ethyl oleate, Olive oil, castor oil, HCO 40), surfactant ( Tween 20, Tween 80, Cremophore RH 40, Lauroglycol) and co-surfactant ( PEG 400, Propylene glycol, Transcutol P, Lutrol 400). The identification of micro emulsifying region is identified by constructing pseudo ternary phase diagram using water titration method. The optimized formulation contain oil phase as LAS (20 % w/w), Tween 20 (5 % w/w) as surfactant and co-surfactant as lutrol 400 (5 % w/w) containing 100 mg Rosuvastatin Calcium. The prepared liquid self micro-emulsion is evaluated for Phase separation (No phase separation for 24 hrs at room temperature), Self micro emulsifying time (less than 1 min), Particle size (0.2 micron), robustness to dilution (no phase separation), In-vitro dissolution study in distilled water. The in-vitro dissolution study showed improvement in solubility of Rosuvastatin Calcium over plain Rosuvastatin calcium.
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