Pub Date : 2024-07-10DOI: 10.47552/ijam.v15i2.4604
S. Rathod, Supriya S Kaule, P. Bawankar
Background: The therapeutic effects of Picrorhiza kurroa Royle ex benth and Ficus benghalensis L. for treatment of chronic inflammatory diseases is well known. Objective: The purpose of the present study is assessment of the efficacy of gel containing combination of Picrorhiza kurroa Royle ex benth and Ficus benghalensis L. against periodontopathogens and hydroalcoholic extracts of Picrorhiza kurroa Royle ex benth (PK) and Ficus benghalensis L. (FB) against periodontopathogens. Material & Methods: The preparation of the herbal Water extracts, Alcohol extracts and Hydro Alcoholic extracts was done by Soxhlet extraction method. MIC of different extracts of PK and FB and its combination was determined. Results: The MIC of the PK water extract against Aggregatibacter actinomycetemcomitans (Aa) and Porphyromonas gingivalis (Pg) was 0.8 μg/ml. For Aa and Pg, the MIC of water extract of FB was 1.6 μg/ml and 6.25 μg/ml, respectively. The combination of PK and FB alcoholic extract was shown to have a MIC of 1.6 μg/ml. Conclusion: The presence of antibacterial activity could be confirmed in periodontopathogens species which were assayed in this study. However, the MIC for the species employed showed a very large range, and were mostly very high. Nevertheless, traditional knowledge might provide some leads to elucidate potential candidates for future development of new antibiotic agents.
背景：Picrorhiza kurroa Royle ex benth 和 Ficus benghalensis L.治疗慢性炎症性疾病的疗效众所周知。研究目的本研究的目的是评估含有本酸豆属植物和榕属植物复方凝胶以及本酸豆属植物（PK）和榕属植物（FB）水醇提取物的凝胶对牙周病原体的疗效。材料与方法： 采用索氏提取法制备草药水提取物、醇提取物和水醇提取物。测定了 PK 和 FB 不同提取物及其组合的 MIC。结果：PK 水提取物对放线菌（Aa）和牙龈卟啉单胞菌（Pg）的 MIC 为 0.8 μg/ml。对于 Aa 和 Pg，FB 水提取物的 MIC 分别为 1.6 μg/ml 和 6.25 μg/ml。PK 和 FB 酒精提取物组合的 MIC 为 1.6 μg/ml。结论本研究中检测的牙周病原体种类均具有抗菌活性。不过，所采用的物种的 MIC 值范围很大，而且大多很高。不过，传统知识可能会提供一些线索，为今后开发新的抗生素制剂提供潜在的候选药物。
{"title":"Determination of Minimal Inhibitory Concentration of Gel containing combination of Picrorhiza Kurroa and Ficus Benghalensis for Treatment of Periodontitis","authors":"S. Rathod, Supriya S Kaule, P. Bawankar","doi":"10.47552/ijam.v15i2.4604","DOIUrl":"https://doi.org/10.47552/ijam.v15i2.4604","url":null,"abstract":"Background: The therapeutic effects of Picrorhiza kurroa Royle ex benth and Ficus benghalensis L. for treatment of chronic inflammatory diseases is well known. Objective: The purpose of the present study is assessment of the efficacy of gel containing combination of Picrorhiza kurroa Royle ex benth and Ficus benghalensis L. against periodontopathogens and hydroalcoholic extracts of Picrorhiza kurroa Royle ex benth (PK) and Ficus benghalensis L. (FB) against periodontopathogens. Material & Methods: The preparation of the herbal Water extracts, Alcohol extracts and Hydro Alcoholic extracts was done by Soxhlet extraction method. MIC of different extracts of PK and FB and its combination was determined. Results: The MIC of the PK water extract against Aggregatibacter actinomycetemcomitans (Aa) and Porphyromonas gingivalis (Pg) was 0.8 μg/ml. For Aa and Pg, the MIC of water extract of FB was 1.6 μg/ml and 6.25 μg/ml, respectively. The combination of PK and FB alcoholic extract was shown to have a MIC of 1.6 μg/ml. Conclusion: The presence of antibacterial activity could be confirmed in periodontopathogens species which were assayed in this study. However, the MIC for the species employed showed a very large range, and were mostly very high. Nevertheless, traditional knowledge might provide some leads to elucidate potential candidates for future development of new antibiotic agents.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141661682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.47552/ijam.v15i2.4242
Shubhangi Kale, Sachin Bhagwat, S. Tavhare, Amrut S. Salunke, S. Sathaye
Background: Chronic hyperglycemia induced oxidative stress may leads to many complications in diabetic patient i.e. nephropathy, neuropathy, retinopathy, stroke, ischemic heart diseases etc. The present study was designed to find the protective effect of polyherbal formulation in rat model of diabetic retinopathy. Material & Methods: Healthy 36 male Wistar rats were randomly divided into four groups namely normal control (n=6), diabetic (n=10), standard metformin (n=10) and test drug (n=10) consisting Triphala (Haritaki, Aamlaki, Bibhitaki), Devdaru, Daruharidra and Musta After induction of diabetes with streptozotocin (45mg/kg), rats were kept without any treatment for period of three weeks for induction of diabetic retinopathy followed by treatment with test drug (540mg/kg) for further 8weeks. HbA1c level was tested. Eye tissue homogenates were subjected to biochemical analysis to evaluate the aldose reductase (AR) activity, oxidative stress parameters namely Superoxide dismutase (SOD), catalase, glutathione (GSH), lipid peroxidation (LPO). Histopathological analysis of retinal tissue was conducted. Results: Test drug showed significant reduction in HBA1C level equivalent to standard metformin. Significant reduction was observed in AR and LPO levels and non-significant reduction in SOD, GSH were observed. Histopathological evaluation indicative of restoration and enhancement in cellular stability of retinal tissues. Conclusion: The herbal formulation showed potent hypoglycemic and antioxidant effect. It can be used as an adjuvant medication in prevention and treatment of diabetic retinopathy.
{"title":"Assessment of polyherbal formulations in managing diabetic retinopathy: An in-vivo experimental model study","authors":"Shubhangi Kale, Sachin Bhagwat, S. Tavhare, Amrut S. Salunke, S. Sathaye","doi":"10.47552/ijam.v15i2.4242","DOIUrl":"https://doi.org/10.47552/ijam.v15i2.4242","url":null,"abstract":"Background: Chronic hyperglycemia induced oxidative stress may leads to many complications in diabetic patient i.e. nephropathy, neuropathy, retinopathy, stroke, ischemic heart diseases etc. The present study was designed to find the protective effect of polyherbal formulation in rat model of diabetic retinopathy. Material & Methods: Healthy 36 male Wistar rats were randomly divided into four groups namely normal control (n=6), diabetic (n=10), standard metformin (n=10) and test drug (n=10) consisting Triphala (Haritaki, Aamlaki, Bibhitaki), Devdaru, Daruharidra and Musta After induction of diabetes with streptozotocin (45mg/kg), rats were kept without any treatment for period of three weeks for induction of diabetic retinopathy followed by treatment with test drug (540mg/kg) for further 8weeks. HbA1c level was tested. Eye tissue homogenates were subjected to biochemical analysis to evaluate the aldose reductase (AR) activity, oxidative stress parameters namely Superoxide dismutase (SOD), catalase, glutathione (GSH), lipid peroxidation (LPO). Histopathological analysis of retinal tissue was conducted. Results: Test drug showed significant reduction in HBA1C level equivalent to standard metformin. Significant reduction was observed in AR and LPO levels and non-significant reduction in SOD, GSH were observed. Histopathological evaluation indicative of restoration and enhancement in cellular stability of retinal tissues. Conclusion: The herbal formulation showed potent hypoglycemic and antioxidant effect. It can be used as an adjuvant medication in prevention and treatment of diabetic retinopathy.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141660037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Traditional medicine is also known by several other terms such as alternative or complementary or folk medicine'. It includes the sum of the total knowledge, health practices approaches and beliefs incorporating plants, animals, minerals, medicines, spiritual therapies, yoga and physical exercises used by different cultures for generations to prevent, diagnose and treat physical and mental illness or to maintain health in a holistic sense. Documentation and evaluation of this indigenous remedial knowledge is essential for the development of the pharmaceutical industry. Some researchers have made an attempt to study and document the usage of medicinal animals by traditional healers. However, there is no scientific documentation on the use of medicinal animals in the treatment for various diseases in the primary health care system by the tribal communities in Goa. Present study is aimed to document different zoo therapeutic medicinal animals and their utilization in the traditional health care system among the Gawda and Dhangar communities, the native tribes of Goa.
{"title":"Zootherapy and ethnozoological studies of Medicinal animals and their products used by the tribal communities in Goa","authors":"Harshada Gaonkar, Akshita Gaonkar, Anjali Velip, Kulkarni Rajender Rao","doi":"10.47552/ijam.v15i2.4624","DOIUrl":"https://doi.org/10.47552/ijam.v15i2.4624","url":null,"abstract":"Traditional medicine is also known by several other terms such as alternative or complementary or folk medicine'. It includes the sum of the total knowledge, health practices approaches and beliefs incorporating plants, animals, minerals, medicines, spiritual therapies, yoga and physical exercises used by different cultures for generations to prevent, diagnose and treat physical and mental illness or to maintain health in a holistic sense. Documentation and evaluation of this indigenous remedial knowledge is essential for the development of the pharmaceutical industry. Some researchers have made an attempt to study and document the usage of medicinal animals by traditional healers. However, there is no scientific documentation on the use of medicinal animals in the treatment for various diseases in the primary health care system by the tribal communities in Goa. Present study is aimed to document different zoo therapeutic medicinal animals and their utilization in the traditional health care system among the Gawda and Dhangar communities, the native tribes of Goa.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141659646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.47552/ijam.v15i2.4679
Aditi Batra, Jayshree V. Changade
Background: Ferula asafoetida Linn. and Coriandrum sativum Linn. belonging to Umbelliferae (Apiaceae) family are used in food for seasoning, restoration of taste, to increase shelf-life and to restore health. Their essential oils and extracts are extensively employed by industrial sector like food industry, beverage industry, fragrance industry, cosmetic industry and pharma industry. However, their use is not limited to food and industrial sector. They have diverse usage in physical ailments, psychological disorder, environmental health. Materials and methods: Data is collected from search engines like Scopus, PubMed, Research Gate, and Google Scholar. Result: Among several herbs used, asafoetida and coriander are only herbs used in spices, medical and environmental well-being. In tradition medicine asafoetida and coriander is used in epilepsy, hysteria, dental carries, alcoholism, stomach-ache, flatulence and coriander in rheumatoid arthritis, emesis, indigestion, fever, conjunctivitis and indolent swelling etc. Aside of this, they are widely used as botanical pesticides since pharmacological researches has shown that they have insecticidal, larvicidal, insect repellent, ovicidal, and acaricidal properties. As compared to manufactured chemicals, botanicals are thought to be less hazardous to the environment and human health. Recently, neuroprotective, antidepressant/ anxiolytic, learning and memory improvement, insecticidal, larvicidal, insect repellent, antifungal, antimicrobial, anti-helminthic, gastroprotective etc properties are proven pharmacologically and biologically in animal models and humans. Conclusion: Use of essential oils should be employed in physical, psychological and environmental health by various means such as aroma therapy, topical application, inhalation, ingestion, colognes, spray and baths, not only eradicate the disease but also to rejuvenate the whole body.
{"title":"Ferula asafoetida Linn. and Coriandrum sativum Linn. - A review on physical, psychological and environmental health","authors":"Aditi Batra, Jayshree V. Changade","doi":"10.47552/ijam.v15i2.4679","DOIUrl":"https://doi.org/10.47552/ijam.v15i2.4679","url":null,"abstract":"Background: Ferula asafoetida Linn. and Coriandrum sativum Linn. belonging to Umbelliferae (Apiaceae) family are used in food for seasoning, restoration of taste, to increase shelf-life and to restore health. Their essential oils and extracts are extensively employed by industrial sector like food industry, beverage industry, fragrance industry, cosmetic industry and pharma industry. However, their use is not limited to food and industrial sector. They have diverse usage in physical ailments, psychological disorder, environmental health. Materials and methods: Data is collected from search engines like Scopus, PubMed, Research Gate, and Google Scholar. Result: Among several herbs used, asafoetida and coriander are only herbs used in spices, medical and environmental well-being. In tradition medicine asafoetida and coriander is used in epilepsy, hysteria, dental carries, alcoholism, stomach-ache, flatulence and coriander in rheumatoid arthritis, emesis, indigestion, fever, conjunctivitis and indolent swelling etc. Aside of this, they are widely used as botanical pesticides since pharmacological researches has shown that they have insecticidal, larvicidal, insect repellent, ovicidal, and acaricidal properties. As compared to manufactured chemicals, botanicals are thought to be less hazardous to the environment and human health. Recently, neuroprotective, antidepressant/ anxiolytic, learning and memory improvement, insecticidal, larvicidal, insect repellent, antifungal, antimicrobial, anti-helminthic, gastroprotective etc properties are proven pharmacologically and biologically in animal models and humans. Conclusion: Use of essential oils should be employed in physical, psychological and environmental health by various means such as aroma therapy, topical application, inhalation, ingestion, colognes, spray and baths, not only eradicate the disease but also to rejuvenate the whole body.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141660902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.47552/ijam.v15i2.4653
Gulten Okmen, Ayhan Guler
Dental caries and periodontal diseases are common oral conditions associated with the formation of dental plaque. Dental plaque is composed of the oral microbiota and accumulates on the tooth surface. Despite the development of numerous antiseptic agents to control bacterial growth, the issue of bacterial resistance has prompted scientists to explore new avenues. As the problem of bacterial resistance continues to grow, studies in this field become increasingly crucial. Medicinal plants offer the best resources for this purpose, and Melissa officinalis L. is one such plant. This study aims to determine the antibacterial and antioxidant activities of Melissa officinalis against bacteria isolated from the oral microbiota. In the study, 8 bacteria were used as the organism source, and Melissa officinalis was utilized as the plant source. The extraction of the plant was carried out using ethanol, methanol, and water. All extracts were evaluated for their antibacterial activities using the disk diffusion method. Antioxidant activity studies were conducted using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method. At the end of the study, the highest antibacterial activity was obtained from the ethanol extract of Melissa officinalis, with a 26 mm inhibition zone diameter against Staphylococcus epidermidis MBKK7. The highest antioxidant activity was determined to be 87.34% DPPH radical scavenging activity from the methanol extract of Melissa officinalis. As a result, it has been determined that Melissa officinalis exhibits both high antibacterial and antioxidant activities. It can be suggested that M. officinalis may serve as an effective natural protector against oral pathogens.
{"title":"Antibacterial activities of Melissa officinalis (Lamiaceae) aerial parts extracts against bacteria isolated from the oral microflora, and their antioxidant properties","authors":"Gulten Okmen, Ayhan Guler","doi":"10.47552/ijam.v15i2.4653","DOIUrl":"https://doi.org/10.47552/ijam.v15i2.4653","url":null,"abstract":"Dental caries and periodontal diseases are common oral conditions associated with the formation of dental plaque. Dental plaque is composed of the oral microbiota and accumulates on the tooth surface. Despite the development of numerous antiseptic agents to control bacterial growth, the issue of bacterial resistance has prompted scientists to explore new avenues. As the problem of bacterial resistance continues to grow, studies in this field become increasingly crucial. Medicinal plants offer the best resources for this purpose, and Melissa officinalis L. is one such plant. This study aims to determine the antibacterial and antioxidant activities of Melissa officinalis against bacteria isolated from the oral microbiota. In the study, 8 bacteria were used as the organism source, and Melissa officinalis was utilized as the plant source. The extraction of the plant was carried out using ethanol, methanol, and water. All extracts were evaluated for their antibacterial activities using the disk diffusion method. Antioxidant activity studies were conducted using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method. At the end of the study, the highest antibacterial activity was obtained from the ethanol extract of Melissa officinalis, with a 26 mm inhibition zone diameter against Staphylococcus epidermidis MBKK7. The highest antioxidant activity was determined to be 87.34% DPPH radical scavenging activity from the methanol extract of Melissa officinalis. As a result, it has been determined that Melissa officinalis exhibits both high antibacterial and antioxidant activities. It can be suggested that M. officinalis may serve as an effective natural protector against oral pathogens.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141660047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.47552/ijam.v15i2.4394
Manisha Panda, Jyothy Kb, Srihari S, Renu Rathi
Prakriti (body constitution) is amalgamation of psychosomatic traits. The inherited features depend upon shukra(sperm) and shonita(ovum), whereas acquired features develop due to environmental elements. Aim of this contemporary study is to assess Prakriti of neonates by psychosomatic and neurological characteristics and objectives are to prepare a comprehensive proforma to assess Prakriti (body constitution) in neonates by using subjective criteria, psychosomatic and neurological characteristics. Material & methods: A total of 100 neonates fulfilling inclusion criteria were enrolled from OPD, IPD of MGACH & RC, DMIHER and NICU, A.V.B.R.H., Sawangi, Wardha, Maharashtra and this prevailing study was conducted as a survey study using a validated questionnaire. Compilation of a comprehensive list of distinctive traits (predictors) for Prakriti evaluation found in Ayurvedic texts (grouping of items) was used to create N-PAS. Observations & Result: 100 neonates were taken and after applying frequency distribution in descriptive statistics and one-way ANOVA in inferential statistics to compare concerned parameters in the N-PAS with anthropometrical measurements, it was observed that Kapha-Vataj Prakriti was found to be more dominant with 27% because in early childhood, kapha dosha is found to be the paramount one. Discussion and Conclusion: This study has a vital role in determining the role of Prakriti in promotion of health, agni status of individual, determination of bala/ strength, diagnosis, management of diseases, prognosis, decision of preventive medicine, determination of genomic relevance with doshik predominance. N-PAS (comprehensive neonatal Prakriti assessment scale) was formed and by analytical statistics, Kapha-Vataj Prakriti (27%) was found to be more dominant.
{"title":"Development of tools of Prakriti assessment in neonates- A cross sectional study","authors":"Manisha Panda, Jyothy Kb, Srihari S, Renu Rathi","doi":"10.47552/ijam.v15i2.4394","DOIUrl":"https://doi.org/10.47552/ijam.v15i2.4394","url":null,"abstract":"Prakriti (body constitution) is amalgamation of psychosomatic traits. The inherited features depend upon shukra(sperm) and shonita(ovum), whereas acquired features develop due to environmental elements. Aim of this contemporary study is to assess Prakriti of neonates by psychosomatic and neurological characteristics and objectives are to prepare a comprehensive proforma to assess Prakriti (body constitution) in neonates by using subjective criteria, psychosomatic and neurological characteristics. Material & methods: A total of 100 neonates fulfilling inclusion criteria were enrolled from OPD, IPD of MGACH & RC, DMIHER and NICU, A.V.B.R.H., Sawangi, Wardha, Maharashtra and this prevailing study was conducted as a survey study using a validated questionnaire. Compilation of a comprehensive list of distinctive traits (predictors) for Prakriti evaluation found in Ayurvedic texts (grouping of items) was used to create N-PAS. Observations & Result: 100 neonates were taken and after applying frequency distribution in descriptive statistics and one-way ANOVA in inferential statistics to compare concerned parameters in the N-PAS with anthropometrical measurements, it was observed that Kapha-Vataj Prakriti was found to be more dominant with 27% because in early childhood, kapha dosha is found to be the paramount one. Discussion and Conclusion: This study has a vital role in determining the role of Prakriti in promotion of health, agni status of individual, determination of bala/ strength, diagnosis, management of diseases, prognosis, decision of preventive medicine, determination of genomic relevance with doshik predominance. N-PAS (comprehensive neonatal Prakriti assessment scale) was formed and by analytical statistics, Kapha-Vataj Prakriti (27%) was found to be more dominant.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141661603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.47552/ijam.v15i2.4616
Mihai Covaci, Brindusa Covaci, Carla Selma
Aims and objectives: This study systematically investigates Apis Mellifera honey as an integral component within the beekeeping value chain, specifically emphasizing its role in apicultural mountain production. Methods: The research delves into multifaceted dimensions, encompassing agronomical and territorial profiles, generated through the utilization of the Paintmap online software. Additionally, the investigation employs experimental and statistical perspectives, utilizing SPSS and Excel software for analysis. Important observations and results: The outcomes of this comprehensive analysis reveal a noteworthy evolution in the Apis Mellifera honey market, particularly during the prevailing pandemic circumstances. The findings elucidate a discernible surge in market development over recent years. Ultimately, the paper posits that the value chain associated with Apis Mellifera mountain honey originating from European Romania substantiates a substantial foundation for mountain production and agricultural practices. In summation, this exploration contributes to the scholarly understanding of the intricate dynamics within the apicultural sector, shedding light on the pivotal role of Apis Mellifera honey in sustaining robust mountain production and farming activities.
{"title":"Apis mellifera honey: Healing effects - A value chain view from mountain agriculture","authors":"Mihai Covaci, Brindusa Covaci, Carla Selma","doi":"10.47552/ijam.v15i2.4616","DOIUrl":"https://doi.org/10.47552/ijam.v15i2.4616","url":null,"abstract":"Aims and objectives: This study systematically investigates Apis Mellifera honey as an integral component within the beekeeping value chain, specifically emphasizing its role in apicultural mountain production. \u0000Methods: The research delves into multifaceted dimensions, encompassing agronomical and territorial profiles, generated through the utilization of the Paintmap online software. Additionally, the investigation employs experimental and statistical perspectives, utilizing SPSS and Excel software for analysis. \u0000Important observations and results: The outcomes of this comprehensive analysis reveal a noteworthy evolution in the Apis Mellifera honey market, particularly during the prevailing pandemic circumstances. The findings elucidate a discernible surge in market development over recent years. Ultimately, the paper posits that the value chain associated with Apis Mellifera mountain honey originating from European Romania substantiates a substantial foundation for mountain production and agricultural practices. In summation, this exploration contributes to the scholarly understanding of the intricate dynamics within the apicultural sector, shedding light on the pivotal role of Apis Mellifera honey in sustaining robust mountain production and farming activities.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141659666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.47552/ijam.v15i2.4809
Nayana Bhagat, Laxmikant Dyamani, Dhulappa Mehatre, Nikhil Gawas, Suketha S
Inefficiency of medical therapies used in order to cure patients with microbial infestations requires safe, effective new antimicrobial agents based on variety of parameters. Ayurveda being a holistic science uses many such safe and effective herbal and herbo-mineral interventions in the management of microbial infestations. Nimba (Azadirachta indica A. Juss) is one commonly available and well known medicinal plant used as krimihara dravya (antimicrobial drug). It has tikta, rasa (bitter taste), Laghu guna (light in property) sheeta veerya (cold in potency), katu vipaka (pungent of metabolism) act as krimighna (Antimicrobial), kusthaghna (alleviates Skin disease), vranaropana (wound healing), raktashodhaka (blood purifier). Also it acts as antioxidant, inhibits bacterial growth. Aim and objectives: To evaluate the physico- phyto-constituents and to assess anti-microbial effect of aqueous extract of Nimba patra. Materials and methods: The official part of the trial drug was subjected for exhaustive extraction by using distilled water and analyzed for physico-chemical, phyto-chemical analysis and antimicrobial evaluation by using aqueous extract on Staphylococcus aureus (SA), Pseudomonas aeruginosa (PA), Proteus mirabilis (PM), E. coli (EC) and Candida albicans (CA) with Agar well diffusion method to asses Minimum Inhibitory concentration, Minimal Bactericidal Concentration with a dose of Stock 10g/10ml. Observation and results: Physico-chemical study shows 4.63%w/w moisture content, 9.05%w/w Ash content, 5.16 pH value, phyto-chemical analysis indicates the presence of tannins, flavonoids, alkaloids, and anti- microbial study of aqueous extract of nimbi patra shows significant effect on bacteria and fungus in comparison with known standard drug.
{"title":"Analytico-in-vitro experimental study of aqueous extract of Neem (Azadirachta indica A. Juss) patra vis-a-vis anti-microbial effect","authors":"Nayana Bhagat, Laxmikant Dyamani, Dhulappa Mehatre, Nikhil Gawas, Suketha S","doi":"10.47552/ijam.v15i2.4809","DOIUrl":"https://doi.org/10.47552/ijam.v15i2.4809","url":null,"abstract":"Inefficiency of medical therapies used in order to cure patients with microbial infestations requires safe, effective new antimicrobial agents based on variety of parameters. Ayurveda being a holistic science uses many such safe and effective herbal and herbo-mineral interventions in the management of microbial infestations. Nimba (Azadirachta indica A. Juss) is one commonly available and well known medicinal plant used as krimihara dravya (antimicrobial drug). It has tikta, rasa (bitter taste), Laghu guna (light in property) sheeta veerya (cold in potency), katu vipaka (pungent of metabolism) act as krimighna (Antimicrobial), kusthaghna (alleviates Skin disease), vranaropana (wound healing), raktashodhaka (blood purifier). Also it acts as antioxidant, inhibits bacterial growth. Aim and objectives: To evaluate the physico- phyto-constituents and to assess anti-microbial effect of aqueous extract of Nimba patra. Materials and methods: The official part of the trial drug was subjected for exhaustive extraction by using distilled water and analyzed for physico-chemical, phyto-chemical analysis and antimicrobial evaluation by using aqueous extract on Staphylococcus aureus (SA), Pseudomonas aeruginosa (PA), Proteus mirabilis (PM), E. coli (EC) and Candida albicans (CA) with Agar well diffusion method to asses Minimum Inhibitory concentration, Minimal Bactericidal Concentration with a dose of Stock 10g/10ml. Observation and results: Physico-chemical study shows 4.63%w/w moisture content, 9.05%w/w Ash content, 5.16 pH value, phyto-chemical analysis indicates the presence of tannins, flavonoids, alkaloids, and anti- microbial study of aqueous extract of nimbi patra shows significant effect on bacteria and fungus in comparison with known standard drug.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141662773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.47552/ijam.v15i2.4503
Twinkle Joshi, Vaishali Kuchewar, Aman Chhabra
In Ayurveda, Sthaulya is santarpanothha vyadhi caused by excessive accumulation of Meda resulting in pendulous appearance of Sphik, Udara and Stana. It can be correlated with overweight or obesity. Obesity is characterized by abnormal growth of adipose tissue due to enlargement of fat cell size or number which is expressed in BMI, 24.9 kg/m2 to 29.9 kg/m2 indicates overweight and >30 kg/m2 indicates obesity. Studies have been conducted on medications like medohar guggulu, navaka guggulu but Medohar Arka was relatively unexplored. It is a low cost medicine described by Ras Tantra Saara and Siddha Prayoga Sangraha for sthaulya. Material and Methods-Study comprised of 66 participants between age group of 20-50 years, either sex, having B.M.I. between 25-30 kg/m2. Group M was treated with Medohar Arka 15ml twice daily before food with equal amount of water whereas Group P was treated with Placebo 250 mg twice daily before food with equal amount water for 90 days. Pathyapathya and vyayama was advised to both groups in the form of Ahar (Diet) and Vihar(30 min brisk walk). Assessment was done on day 0 and day 90 (completion of treatment). Participants were assessed for objective parameters like Body Mass Index, Waist Hip Ratio(WHR) and Mid Arm circumference(MAC). On comparing both the groups, statistically significant improvement was observed in Body Mass Index, Waist Hip Ratio, Mid Arm circumference in Medohar arka group. Conclusion- Medohar Arka was effective in managing overweight. Further study could be conducted on obese patients for generalized use of this medicine.
{"title":"Efficacy of Medohar Arka in Sthaulya (Overweight) – A single blind placebo controlled clinical study","authors":"Twinkle Joshi, Vaishali Kuchewar, Aman Chhabra","doi":"10.47552/ijam.v15i2.4503","DOIUrl":"https://doi.org/10.47552/ijam.v15i2.4503","url":null,"abstract":"In Ayurveda, Sthaulya is santarpanothha vyadhi caused by excessive accumulation of Meda resulting in pendulous appearance of Sphik, Udara and Stana. It can be correlated with overweight or obesity. Obesity is characterized by abnormal growth of adipose tissue due to enlargement of fat cell size or number which is expressed in BMI, 24.9 kg/m2 to 29.9 kg/m2 indicates overweight and >30 kg/m2 indicates obesity. Studies have been conducted on medications like medohar guggulu, navaka guggulu but Medohar Arka was relatively unexplored. It is a low cost medicine described by Ras Tantra Saara and Siddha Prayoga Sangraha for sthaulya. Material and Methods-Study comprised of 66 participants between age group of 20-50 years, either sex, having B.M.I. between 25-30 kg/m2. Group M was treated with Medohar Arka 15ml twice daily before food with equal amount of water whereas Group P was treated with Placebo 250 mg twice daily before food with equal amount water for 90 days. Pathyapathya and vyayama was advised to both groups in the form of Ahar (Diet) and Vihar(30 min brisk walk). Assessment was done on day 0 and day 90 (completion of treatment). Participants were assessed for objective parameters like Body Mass Index, Waist Hip Ratio(WHR) and Mid Arm circumference(MAC). On comparing both the groups, statistically significant improvement was observed in Body Mass Index, Waist Hip Ratio, Mid Arm circumference in Medohar arka group. Conclusion- Medohar Arka was effective in managing overweight. Further study could be conducted on obese patients for generalized use of this medicine.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141660115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-10DOI: 10.47552/ijam.v15i2.4447
Nishahun Wahlang, Renu Rathi
Background: In Ayurveda, Stanya Dosha was described by almost all Acharya stating the Dushti of breast milk which is not accepted by modern sciences as they perceived that breast milk is exclusively advised to all neonates and there is no such description to examine the abnormality of breast milk. As Ayurveda literature is Shaswat (eternal) which gives us a reason for the need to provide evidence or scientific explanation to support our literature. To make the world aware of Stanya Dushti, scientific evidences must be provided for other scientific systems to embrace the notion. Aim: To assess the quality of Stanya by examining its features as told in Ayurveda literature and its physicochemical properties. Objectives: To establish assessment criteria to assess Stanya Dushti through basic sciences. To assess the Stanya by observing the organoleptic property. Experiment with its physicochemical properties of protein estimation, viscosity, pH, value, and density. To assess the Dosha of breast milk by Jala pariksha(Dispersion method). Materials and methods: Observational study on breast milk of 60 lactating mothers collected from mothers coming for vaccination & OPD of MGACH&RC, PHC Salod, Wardha. Observation: 38.3% were Shuddha and 61.7% were Ashuddha with 11.7%Vatapitta, 25% Kaphapitta, 11.7%Vata, 5% Pitta,and 8.3% Kaphadominance. Mean values of pH, viscosity, density, and protein were found as 6.91, 1.64 cP, 1.02 gm/cc, and 1.72% respectively. Result: The breast milk of Shuddha stanya part was 38.3% and that of Dushti was 61%. The dominance of Dosha shows highly significance with Prakriti. The infants with Stanya Dushti show significant risks of developing clinical symptoms of GIT and the respiratory system.
{"title":"Evaluation of the physiological and pathological status of Stanya (Breast milk) based on the Ayurveda principles and Physico-chemical analysis- A Cross-sectional study","authors":"Nishahun Wahlang, Renu Rathi","doi":"10.47552/ijam.v15i2.4447","DOIUrl":"https://doi.org/10.47552/ijam.v15i2.4447","url":null,"abstract":"Background: In Ayurveda, Stanya Dosha was described by almost all Acharya stating the Dushti of breast milk which is not accepted by modern sciences as they perceived that breast milk is exclusively advised to all neonates and there is no such description to examine the abnormality of breast milk. As Ayurveda literature is Shaswat (eternal) which gives us a reason for the need to provide evidence or scientific explanation to support our literature. To make the world aware of Stanya Dushti, scientific evidences must be provided for other scientific systems to embrace the notion. Aim: To assess the quality of Stanya by examining its features as told in Ayurveda literature and its physicochemical properties. Objectives: To establish assessment criteria to assess Stanya Dushti through basic sciences. To assess the Stanya by observing the organoleptic property. Experiment with its physicochemical properties of protein estimation, viscosity, pH, value, and density. To assess the Dosha of breast milk by Jala pariksha(Dispersion method). Materials and methods: Observational study on breast milk of 60 lactating mothers collected from mothers coming for vaccination & OPD of MGACH&RC, PHC Salod, Wardha. Observation: 38.3% were Shuddha and 61.7% were Ashuddha with 11.7%Vatapitta, 25% Kaphapitta, 11.7%Vata, 5% Pitta,and 8.3% Kaphadominance. Mean values of pH, viscosity, density, and protein were found as 6.91, 1.64 cP, 1.02 gm/cc, and 1.72% respectively. Result: The breast milk of Shuddha stanya part was 38.3% and that of Dushti was 61%. The dominance of Dosha shows highly significance with Prakriti. The infants with Stanya Dushti show significant risks of developing clinical symptoms of GIT and the respiratory system.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141659214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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