Pub Date : 2023-10-03DOI: 10.47552/ijam.v14i3.3890
VijayaLekshmi R, M.A. Shajahan, Indulekha V C
Nootropics are groups of medicines which are known to act as memory enhancers. There is a growing need for such medicines from alternate systems of medicine to prevent or delay memory loss and related disorders. Classical textbooks in Ayurveda describe a group called as Medhya Rasayana, which act as neuro-nutrients. Chathushkuvalaya Rasayana is one such ghee preparation mentioned in Ashtangahrdaya. In it, Kuvalaya, botanically identified in Kerala as Monochoria vaginalis Presl. is the only herbal ingredient. Though Kuvalaya has been considered widely as a memory enhancer, there is scarce published literature regarding standardisation aspects of Kuvalaya ghrta. In this work, we have phytochemically standardized the ingredients of Kuvalayaghrta including its Atomic Absorption spectroscopy, Thin Layer Chromatography (TLC) and High-Performance Thin Layer Chromatography (HPTLC) profiling followed by the preparation of the ghrta(ghee) according to the standard procedure mentioned in Ayurvedic Formulary of India. Kuvalayaghrta was also standardised physicochemically and was found to be safe for internal administration. All the observations obtained in this study can be used for future reference.
{"title":"Standardisation of Kuvalayaghrta: A Potential Nootropic Supplement","authors":"VijayaLekshmi R, M.A. Shajahan, Indulekha V C","doi":"10.47552/ijam.v14i3.3890","DOIUrl":"https://doi.org/10.47552/ijam.v14i3.3890","url":null,"abstract":"Nootropics are groups of medicines which are known to act as memory enhancers. There is a growing need for such medicines from alternate systems of medicine to prevent or delay memory loss and related disorders. Classical textbooks in Ayurveda describe a group called as Medhya Rasayana, which act as neuro-nutrients. Chathushkuvalaya Rasayana is one such ghee preparation mentioned in Ashtangahrdaya. In it, Kuvalaya, botanically identified in Kerala as Monochoria vaginalis Presl. is the only herbal ingredient. Though Kuvalaya has been considered widely as a memory enhancer, there is scarce published literature regarding standardisation aspects of Kuvalaya ghrta. In this work, we have phytochemically standardized the ingredients of Kuvalayaghrta including its Atomic Absorption spectroscopy, Thin Layer Chromatography (TLC) and High-Performance Thin Layer Chromatography (HPTLC) profiling followed by the preparation of the ghrta(ghee) according to the standard procedure mentioned in Ayurvedic Formulary of India. Kuvalayaghrta was also standardised physicochemically and was found to be safe for internal administration. All the observations obtained in this study can be used for future reference.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135648616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-03DOI: 10.47552/ijam.v14i3.3507
Manojkumar Chaudhari, Yogita Chaudhari
Background: The existence of significant bioactive compounds in herbs makes them pharmacologically treasured. Aragvadha (Cassia fistula Linn.), generally known as 'golden shower tree' is popular for its medicinal properties in Ayurveda. The fruit pulp of it owns medicinal values. Each plant has certain bioactive important compounds. For the extraction of different vital compounds, there is a need of specific method of extraction, which are known as ‘panchavidha kashaya kalpana’ (five varieties of extraction) in Ayurveda. These are - Svarasa (expressed juice), Kalka (paste), Kvatha (decoction), Hima (cold infusion) and Phanta (hot infusion). From centuries, Ayurvedic physicians are using extraction method, called as 'phanta' (hot infusion) for the fruit pulp of Aragvadha as a conventional technique; Ayurvedic scriptures also recommend the 'kvatha' (decoction) extraction process. To assess the superiority of these two extraction procedures, the present work used high-performance thin layer chromatography (HPTLC) analysis of Aragvadha (Cassia fistula Linn.) fruit pulp methanolic extract for phytochemical profiling. Results: The HPTLC analysis of Aragvadha (Cassia fistula Linn.) fruit pulp methanolic extract was carried out using winCATS Planar Chromatography Manager system, and the outcomes, which were obtained as chromatograms (scanned at the wavelength of 254 nm and 366 nm) representing multiple peaks. The plant's phytochemical profile of both samples were established, and tables indicating the total count of peaks with the height, area, percent area of peaks, and Rf values. Conclusion: The study revealed that the 'kadha' (decoction) of Aragvadha (Cassia fistula Linn.) fruit pulp methanolic extract contains a rich variety of phytochemicals as compare to 'phanta' (hot infusion) which might be accountable for its therapeutic value and thus justifies superiority of the 'kadha' (decoction) extraction method.
{"title":"Comparison of the two extraction methods of fruit pulp of Aragvadha (Cassia fistula Linn.) by HPTLC","authors":"Manojkumar Chaudhari, Yogita Chaudhari","doi":"10.47552/ijam.v14i3.3507","DOIUrl":"https://doi.org/10.47552/ijam.v14i3.3507","url":null,"abstract":"Background: The existence of significant bioactive compounds in herbs makes them pharmacologically treasured. Aragvadha (Cassia fistula Linn.), generally known as 'golden shower tree' is popular for its medicinal properties in Ayurveda. The fruit pulp of it owns medicinal values. Each plant has certain bioactive important compounds. For the extraction of different vital compounds, there is a need of specific method of extraction, which are known as ‘panchavidha kashaya kalpana’ (five varieties of extraction) in Ayurveda. These are - Svarasa (expressed juice), Kalka (paste), Kvatha (decoction), Hima (cold infusion) and Phanta (hot infusion). From centuries, Ayurvedic physicians are using extraction method, called as 'phanta' (hot infusion) for the fruit pulp of Aragvadha as a conventional technique; Ayurvedic scriptures also recommend the 'kvatha' (decoction) extraction process. To assess the superiority of these two extraction procedures, the present work used high-performance thin layer chromatography (HPTLC) analysis of Aragvadha (Cassia fistula Linn.) fruit pulp methanolic extract for phytochemical profiling. Results: The HPTLC analysis of Aragvadha (Cassia fistula Linn.) fruit pulp methanolic extract was carried out using winCATS Planar Chromatography Manager system, and the outcomes, which were obtained as chromatograms (scanned at the wavelength of 254 nm and 366 nm) representing multiple peaks. The plant's phytochemical profile of both samples were established, and tables indicating the total count of peaks with the height, area, percent area of peaks, and Rf values. Conclusion: The study revealed that the 'kadha' (decoction) of Aragvadha (Cassia fistula Linn.) fruit pulp methanolic extract contains a rich variety of phytochemicals as compare to 'phanta' (hot infusion) which might be accountable for its therapeutic value and thus justifies superiority of the 'kadha' (decoction) extraction method.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135788417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-03DOI: 10.47552/ijam.v14i3.3606
Suguna M, Aravinda Senbagaraman R, Arthi G, Kavitha S, Priyadharshini S, Krishnaveni M
Siddha science is an immortal science, which has its origin from ‘Siddhars’. The Siddha system is mainly based on the humoral theory. The three humors namely Vatham, Pitham and Kapham. Any increase or decrease in the ratio of the three humors causes disease in the human body. In the Siddha system of medicine, diseases are classified into 4448 in number. Out of these Yugi Munivar classified Vatham as 80 types. The symptoms of Trigeminal Neuralgia come under this Vatha classification. The elevated Vatham is decreased by giving purgation therapy based on the quote ‘Bhedhiyaal Vatham Thaalum’. Agasthiyar Kuzhambu is one of the best commonly used purgative medicine in the Siddha System.Trigeminal neuralgia is one of the painful disorders involving the fifth cranial nerve and causes severe unilateral pain in the face over regions supplied by the branches of the trigeminal nerve[5]. The present study is conducted to know the efficacy of Siddha Purgation Therapy for the management of trigeminal neuralgia on the basis of the quote “Bhedhiyaal Vatham Thaalum”. A female patient of 56 years, diagnosed with trigeminal neuralgia approached our hospital and got purgation therapy using Agasthiyar Kuzhambu for 3 days. Patient complaints were assessed before and after treatment with 1) Siddha diagnostic tool neerkuri and neikuri, 2) Questionnaire about increased Vatha symptoms and 3)Visual Analog Scale (VAS) pain scale. After giving Agasthiyar Kuzhambu follow up the patient she got relieved from their symptoms and got satisfactory results with the Siddha line of management. The possible understanding of the case and therapeutic protocol in Siddha has been discussed.
{"title":"Purgation therapy (bhedhi) in the treatment of Trigeminal neuralgia and evaluation using Siddha diagnostic tool neerkuri and neikuri – A Case study","authors":"Suguna M, Aravinda Senbagaraman R, Arthi G, Kavitha S, Priyadharshini S, Krishnaveni M","doi":"10.47552/ijam.v14i3.3606","DOIUrl":"https://doi.org/10.47552/ijam.v14i3.3606","url":null,"abstract":"Siddha science is an immortal science, which has its origin from ‘Siddhars’. The Siddha system is mainly based on the humoral theory. The three humors namely Vatham, Pitham and Kapham. Any increase or decrease in the ratio of the three humors causes disease in the human body. In the Siddha system of medicine, diseases are classified into 4448 in number. Out of these Yugi Munivar classified Vatham as 80 types. The symptoms of Trigeminal Neuralgia come under this Vatha classification. The elevated Vatham is decreased by giving purgation therapy based on the quote ‘Bhedhiyaal Vatham Thaalum’. Agasthiyar Kuzhambu is one of the best commonly used purgative medicine in the Siddha System.Trigeminal neuralgia is one of the painful disorders involving the fifth cranial nerve and causes severe unilateral pain in the face over regions supplied by the branches of the trigeminal nerve[5]. The present study is conducted to know the efficacy of Siddha Purgation Therapy for the management of trigeminal neuralgia on the basis of the quote “Bhedhiyaal Vatham Thaalum”. A female patient of 56 years, diagnosed with trigeminal neuralgia approached our hospital and got purgation therapy using Agasthiyar Kuzhambu for 3 days. Patient complaints were assessed before and after treatment with 1) Siddha diagnostic tool neerkuri and neikuri, 2) Questionnaire about increased Vatha symptoms and 3)Visual Analog Scale (VAS) pain scale. After giving Agasthiyar Kuzhambu follow up the patient she got relieved from their symptoms and got satisfactory results with the Siddha line of management. The possible understanding of the case and therapeutic protocol in Siddha has been discussed.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":"132 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135788422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutraceuticals are one of the secondary metabolites that are being produced by diverse group of plants including the horticultural crops. The secondary metabolites in diverse horticultural crops are produced in significant amounts when encountered with different stresses such as wounding stress, abiotic stress, biotic stress, exposure to ultraviolet radiation etc. The secondary metabolite production in the plants enhances their response towards different stresses and help the plants to fight against the stresses in addition to their growth and development. The secondary metabolites expressed in horticultural crops such as phenolic compounds, flavonoids, alkaloids, polyphenols, terpenoids have proven to exhibit number of health benefits such as anti-inflammatory, anti-diabetic, anticancer response. The indepth knowledge of the biosynthetic pathways could lead to the enhancement of the secondary metabolites. Also, the stress responses can be modulated in a ways that could lead to the optimal expression of the genes involved in the production of these secondary metabolites. In the present review article, various horticultural crops including two vegetable and four fruit crops were assessed for the production of secondary metabolites under stress conditions, the biosynthetic pathways leading to the specific secondary metabolite production along with their health benefits have been discussed in detail.
{"title":"The Nutraceutical value of Horticultural Crops","authors":"Ritu Sharma, Priya Singh, Muskan Gupta, Dinesh Kumar Khilla, Palvi Malik, Suruchi Jindal","doi":"10.47552/ijam.v14i3.3788","DOIUrl":"https://doi.org/10.47552/ijam.v14i3.3788","url":null,"abstract":"Nutraceuticals are one of the secondary metabolites that are being produced by diverse group of plants including the horticultural crops. The secondary metabolites in diverse horticultural crops are produced in significant amounts when encountered with different stresses such as wounding stress, abiotic stress, biotic stress, exposure to ultraviolet radiation etc. The secondary metabolite production in the plants enhances their response towards different stresses and help the plants to fight against the stresses in addition to their growth and development. The secondary metabolites expressed in horticultural crops such as phenolic compounds, flavonoids, alkaloids, polyphenols, terpenoids have proven to exhibit number of health benefits such as anti-inflammatory, anti-diabetic, anticancer response. The indepth knowledge of the biosynthetic pathways could lead to the enhancement of the secondary metabolites. Also, the stress responses can be modulated in a ways that could lead to the optimal expression of the genes involved in the production of these secondary metabolites. In the present review article, various horticultural crops including two vegetable and four fruit crops were assessed for the production of secondary metabolites under stress conditions, the biosynthetic pathways leading to the specific secondary metabolite production along with their health benefits have been discussed in detail.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135788425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
It is a well-known fact that the human population of India is increasing very fast. Everybody needs food to survive. Agricultural products must be boosted by adding adequate fertilisers and using appropriate insecticides. Organophosphates are one of the most frequently used insecticides. Their overuse leads to soil contamination by agricultural runoff. The insecticides may enter drinking water as well. Since organophosphates are acetylcholinesterase inhibitors, they can be dangerous for human health if abnormal amounts are present in drinking water or are consumed as residues on fruits and vegetables. Hence, a toxicity study by MTT and Trypan Blue Assay of three common insecticides (Imidacloprid, Profenofos, Dichlorvos) and two natural products (Dashparnik ark and Neem oil) on lymphocytes was taken up. The insecticides were used at concentrations of 1mM, 4mM, 8mM and 12mM. It was found that at 4 hours of incubation at 1mM Imidacloprid showed the greatest drop in viability followed by Dichlorvos and the least harm was caused by Profenofos. The drop was consistent and dose dependent in the case of Profenofos, whereas at a higher concentration the viability generally increased. For 18 hours of incubation, the same trend was observed, but the decrease and increase were more pronounced. In the case of Profenofos and Dichlorvos the viability percent rises above that of the control. It was probably due to the defense mechanism involving the P450 detoxification pathway of the cells, which is activated if they are exposed to a higher concentration of the damaging factors. This is also supported by other workers mentioned in the discussion section of this paper. The damage to the cells, as evident in the fall in viability, was of lesser magnitude when organic insecticides were used. In the case of Neem nano-drop emulsion, a significant fall in viability was noted only at 2mg/ml. However, it is not sprayed as a nano-emulsion because it is not particularly harmful. The fourth insecticide that was taken up for study was Dashparni Ark. In this case, at 5µl/ml of distilled water (obtained by dilution) very little damage was evident, but at higher concentration it boosted the viability. Apparently, the extract of leaves fermented in cow urine and cow dung was less damaging than that of other insecticides. Thus, organic insecticides are safer to use because they are ecofriendly and do not harm non-target organisms. This is written on the basis of MTT assay results.
{"title":"An in vitro study of cytotoxicity of organophosphate insecticides (Imidacloprid, Profenofos, Dichlorvos) and natural products (Neem oil and Dashparni ark) on human peripheral lymphocytes by MTT and Trypan blue assay","authors":"Asha Khanna, Pranita Bhatele, Daya Shankar Gautam, Priyanka Gupta, Vineeta Vaidya, Manoshi Mukherjee, Muskan Kachhi","doi":"10.47552/ijam.v14i3.3832","DOIUrl":"https://doi.org/10.47552/ijam.v14i3.3832","url":null,"abstract":"It is a well-known fact that the human population of India is increasing very fast. Everybody needs food to survive. Agricultural products must be boosted by adding adequate fertilisers and using appropriate insecticides. Organophosphates are one of the most frequently used insecticides. Their overuse leads to soil contamination by agricultural runoff. The insecticides may enter drinking water as well. Since organophosphates are acetylcholinesterase inhibitors, they can be dangerous for human health if abnormal amounts are present in drinking water or are consumed as residues on fruits and vegetables. Hence, a toxicity study by MTT and Trypan Blue Assay of three common insecticides (Imidacloprid, Profenofos, Dichlorvos) and two natural products (Dashparnik ark and Neem oil) on lymphocytes was taken up. The insecticides were used at concentrations of 1mM, 4mM, 8mM and 12mM. It was found that at 4 hours of incubation at 1mM Imidacloprid showed the greatest drop in viability followed by Dichlorvos and the least harm was caused by Profenofos. The drop was consistent and dose dependent in the case of Profenofos, whereas at a higher concentration the viability generally increased. For 18 hours of incubation, the same trend was observed, but the decrease and increase were more pronounced. In the case of Profenofos and Dichlorvos the viability percent rises above that of the control. It was probably due to the defense mechanism involving the P450 detoxification pathway of the cells, which is activated if they are exposed to a higher concentration of the damaging factors. This is also supported by other workers mentioned in the discussion section of this paper. The damage to the cells, as evident in the fall in viability, was of lesser magnitude when organic insecticides were used. In the case of Neem nano-drop emulsion, a significant fall in viability was noted only at 2mg/ml. However, it is not sprayed as a nano-emulsion because it is not particularly harmful. The fourth insecticide that was taken up for study was Dashparni Ark. In this case, at 5µl/ml of distilled water (obtained by dilution) very little damage was evident, but at higher concentration it boosted the viability. Apparently, the extract of leaves fermented in cow urine and cow dung was less damaging than that of other insecticides. Thus, organic insecticides are safer to use because they are ecofriendly and do not harm non-target organisms. This is written on the basis of MTT assay results.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135789894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: In Ayurveda, Pratishyaya (~Recurrent Rhinitis) is described in Shiro-roga (Head disease).Pratishyaya (~Recurrent Rhinitis) is a common disease of childhood and it is well known for its recurrence. Immature Dhatu (tissues) state in children makes them more susceptible to recurrent infections. Clinical features of Pratishyaya (~Recurrent Rhinitis) can be correlated with rhinitis. Aim & Objective: To study the effect of vachadi avaleha and mustakadi avaleha in management of pratishyaya (~recurrent rhinitis). To study comparative efficacy of vachadi avaleha and mustakadi avaleha in management of pratishyaya(~recurrent rhinitis). Material & Method: Study comprises total 60 patients of Pratishyaya (~recurrent rhinitis) randomly divided into two equal groups. Group A (Experimental group) was treated with Vachadi avaleha two times a day after meal with honey and Group B (Control group) was treated with Mustakadi Avaleha administered two times a day after meal for 90 days. Patients were assessed for subjective parameters like rhinorrhoea, sneezing, nasal congestion, recurrence of rhinitis, duration of rhinitis per episode. Patients were assessed on every 30th day till completion of study period. Result- The effect of Mustakadi Avaleha (Group B) is significant at p<0.05 for subjective criteria such as nasastrava (rhinorrhoea), kshavathu (sneezing), and nasavarodha (nasal congestion) of pratishyaya (~Recurrent Rhinitis). Conclusion: Vachadi Avaleha is not as significant as Mustakadi avaleha in Pratishyaya (~Recurrent Rhinitis).
{"title":"A Comparative Clinical Study on the effect of Vachadi Avaleha versus Mustakadi Avaleha in the management of Pratishyaya (~Recurrent Rhinitis) in school going children: A Single-blind Randomized Control Trial","authors":"Prasad Gajanan Yewale, Swapnali Mate, Utkarsha Khaire","doi":"10.47552/ijam.v14i3.3665","DOIUrl":"https://doi.org/10.47552/ijam.v14i3.3665","url":null,"abstract":"Background: In Ayurveda, Pratishyaya (~Recurrent Rhinitis) is described in Shiro-roga (Head disease).Pratishyaya (~Recurrent Rhinitis) is a common disease of childhood and it is well known for its recurrence. Immature Dhatu (tissues) state in children makes them more susceptible to recurrent infections. Clinical features of Pratishyaya (~Recurrent Rhinitis) can be correlated with rhinitis. Aim & Objective: To study the effect of vachadi avaleha and mustakadi avaleha in management of pratishyaya (~recurrent rhinitis). To study comparative efficacy of vachadi avaleha and mustakadi avaleha in management of pratishyaya(~recurrent rhinitis). Material & Method: Study comprises total 60 patients of Pratishyaya (~recurrent rhinitis) randomly divided into two equal groups. Group A (Experimental group) was treated with Vachadi avaleha two times a day after meal with honey and Group B (Control group) was treated with Mustakadi Avaleha administered two times a day after meal for 90 days. Patients were assessed for subjective parameters like rhinorrhoea, sneezing, nasal congestion, recurrence of rhinitis, duration of rhinitis per episode. Patients were assessed on every 30th day till completion of study period. Result- The effect of Mustakadi Avaleha (Group B) is significant at p<0.05 for subjective criteria such as nasastrava (rhinorrhoea), kshavathu (sneezing), and nasavarodha (nasal congestion) of pratishyaya (~Recurrent Rhinitis). Conclusion: Vachadi Avaleha is not as significant as Mustakadi avaleha in Pratishyaya (~Recurrent Rhinitis).","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135788421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-03DOI: 10.47552/ijam.v14i3.3867
Abhishek Kumar Pandey, Smriti Rakesh
Throughout human history, people used to obtain drugs from natural resources like plants to cure their ailments and improve their health. Nowadays human beings rely more on herbal medicines for the treatment of various ailments because they show better therapeutic activity and have very little to zero side effects on the human body. Madhuca longifolia is also one of the plants used in this category. The plant has been used by people for its medicinal properties since the Ayurveda period (before B.C 300). The plant possesses various medicinal activities including anti-proliferative, anti-inflammatory, anti-bacterial, anti-cancer, anti-ulcer and antidiabetic, and antioxidant activity. In various parts of India, the plant is used in the treatment of different diseases in ethnomedicinal practices. The plant possesses several phytochemicals which are responsible for its medicinal properties. The primary focus of this manuscript is to emphasize the significance of diverse ethnomedical characteristics, multiple preclinical investigations, and clinical trials conducted on this particular plant. The study also encompasses the plant's geographical distribution, pharmacognostic and anatomical studies, as well as its various anthropological applications within the Indian subcontinent.
{"title":"Madhuca longifolia var. latifolia (Roxb.) A.Chev: A plant with medicinal boon","authors":"Abhishek Kumar Pandey, Smriti Rakesh","doi":"10.47552/ijam.v14i3.3867","DOIUrl":"https://doi.org/10.47552/ijam.v14i3.3867","url":null,"abstract":"Throughout human history, people used to obtain drugs from natural resources like plants to cure their ailments and improve their health. Nowadays human beings rely more on herbal medicines for the treatment of various ailments because they show better therapeutic activity and have very little to zero side effects on the human body. Madhuca longifolia is also one of the plants used in this category. The plant has been used by people for its medicinal properties since the Ayurveda period (before B.C 300). The plant possesses various medicinal activities including anti-proliferative, anti-inflammatory, anti-bacterial, anti-cancer, anti-ulcer and antidiabetic, and antioxidant activity. In various parts of India, the plant is used in the treatment of different diseases in ethnomedicinal practices. The plant possesses several phytochemicals which are responsible for its medicinal properties. The primary focus of this manuscript is to emphasize the significance of diverse ethnomedical characteristics, multiple preclinical investigations, and clinical trials conducted on this particular plant. The study also encompasses the plant's geographical distribution, pharmacognostic and anatomical studies, as well as its various anthropological applications within the Indian subcontinent.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135789506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-03DOI: 10.47552/ijam.v14i3.3586
Tanvi Mahajan, Bhagawan G Kulkarni
Background: Appreciable progress has been made to study and understand the associations between dermatoglyphics and numerous medical disorders, as a result of which dermatoglyphic analysis has been accepted as a useful diagnostic tool in many diseases particularly those are caused by chromosomal aberrations, which are frequently accompanied by distortion of patterns. Materials and Methods: The aim of this present work is to study the association between characteristic dermatoglyphic features in probands with jatyaandh due to congenital glaucoma compared with age sex matched control. Palmar dermatoglyphic analysis on 20 subjects was carried out. Dermatoglyphics prints were taken by ‘Ink method’ described by Cummins and Mildo, examined for Total Finger Ridge Count (TFRC), Absolute Finger Ridge Count (AFRC), (a-b) ridge count, atd, dat and adt angle (quantitative parameter) and Finger ridge patterns and their frequency (qualitative parameter). Further, statistical analysis is done to find the variations in the dermatoglyphic feature in both groups. Result: The mean values of TFRC, AFRC & atd angle were higher in case group than in controls. The mean value of a-b ridge count is lower in cases as compared to controls. The mean values of dat and adt angle of case group were almost same to that of control group. The highest pattern of distribution of whorls was found in cases whereas radial and ulnar loops are found in controls.
{"title":"Palmar dermatoglyphic profile in Jatyaandh - A Pilot Study","authors":"Tanvi Mahajan, Bhagawan G Kulkarni","doi":"10.47552/ijam.v14i3.3586","DOIUrl":"https://doi.org/10.47552/ijam.v14i3.3586","url":null,"abstract":"Background: Appreciable progress has been made to study and understand the associations between dermatoglyphics and numerous medical disorders, as a result of which dermatoglyphic analysis has been accepted as a useful diagnostic tool in many diseases particularly those are caused by chromosomal aberrations, which are frequently accompanied by distortion of patterns. Materials and Methods: The aim of this present work is to study the association between characteristic dermatoglyphic features in probands with jatyaandh due to congenital glaucoma compared with age sex matched control. Palmar dermatoglyphic analysis on 20 subjects was carried out. Dermatoglyphics prints were taken by ‘Ink method’ described by Cummins and Mildo, examined for Total Finger Ridge Count (TFRC), Absolute Finger Ridge Count (AFRC), (a-b) ridge count, atd, dat and adt angle (quantitative parameter) and Finger ridge patterns and their frequency (qualitative parameter). Further, statistical analysis is done to find the variations in the dermatoglyphic feature in both groups. Result: The mean values of TFRC, AFRC & atd angle were higher in case group than in controls. The mean value of a-b ridge count is lower in cases as compared to controls. The mean values of dat and adt angle of case group were almost same to that of control group. The highest pattern of distribution of whorls was found in cases whereas radial and ulnar loops are found in controls.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135789890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-03DOI: 10.47552/ijam.v14i3.3994
Smitha Nair M K, Rekha Parmar, Anurag Talwar, Sabitha Nair M K, Subhose V
Oyster mushroom (Pleurotus florida) commonly called in India as 'dhingri' develops spontaneously on dead and rotting wooden logs or sporadically on dying trunks of deciduous or coniferous trees in temperate and tropical woodlands. On exposure to sunlight or UV lamp, oyster mushrooms produce concentrations of Vitamin D that are nutritionally significant. Though long periods of storage and different types of cooking tend to decrease the vitamin D level of UV-exposed oyster mushrooms, the vitamin D level in all probability expected to remain at 10ug/100g fresh weight, which is greater than the amount in the majority of foods containing vitamin D and comparable to the recommended daily intake of vitamin D at the global level. Eligible candidates (n=50) were screened by computerized randomization method to receive Pflorida soup during the 03-month study. The efficacy parameters were evaluated through the blood investigation Vit D 25 (OH).
{"title":"Clinical Evaluation of Pleurotus florida (White Oyster Mushroom) – Chatraka in the management of Vitamin D deficiency","authors":"Smitha Nair M K, Rekha Parmar, Anurag Talwar, Sabitha Nair M K, Subhose V","doi":"10.47552/ijam.v14i3.3994","DOIUrl":"https://doi.org/10.47552/ijam.v14i3.3994","url":null,"abstract":"Oyster mushroom (Pleurotus florida) commonly called in India as 'dhingri' develops spontaneously on dead and rotting wooden logs or sporadically on dying trunks of deciduous or coniferous trees in temperate and tropical woodlands. On exposure to sunlight or UV lamp, oyster mushrooms produce concentrations of Vitamin D that are nutritionally significant. Though long periods of storage and different types of cooking tend to decrease the vitamin D level of UV-exposed oyster mushrooms, the vitamin D level in all probability expected to remain at 10ug/100g fresh weight, which is greater than the amount in the majority of foods containing vitamin D and comparable to the recommended daily intake of vitamin D at the global level. Eligible candidates (n=50) were screened by computerized randomization method to receive Pflorida soup during the 03-month study. The efficacy parameters were evaluated through the blood investigation Vit D 25 (OH).","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135789900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-03DOI: 10.47552/ijam.v14i3.3738
Bharathy Kannan, Lakshmi Kantham T, Meena Kumari R
Background: Hemorrhoid disease is the fourth leading out-patient gastrointestinal diagnosis in world wide. It arises from congestion of the internal and/or external venous plexuses around the anal canal.
Aim: The aim of this study was to evaluate the therapeutic effectiveness of siddha herbal formulation Oma chooranam in the management of moolam (Internal Hemorrhoids) patients through proctoscopy and Hemorrhoid Symptom Score (HSS) before and after treatment.
Materials and Methods: This study was an open non randomized clinical trial and it was was conducted after getting Institutional Ethical Committee clearance. Patients (N=10) diagnosed with moolam (internal haemorrhoids) using proctscopy results, were enrolled in the study over a period of 6 months (from February 2022 to August 2022). Each patient received 3grams of Oma chooranam mixed in warm water twice a day, for 24 days and patients were followed up for 2 months. The main outcome measure of this study was efficacy assessment, which was measured by using Haemorrhoid Symptom Severity scores(HSS Score) on Day-0 (baseline) and 25th day.
Result and conclusion: Biostatistical p value using Wilcoxon signed rank test of HSS scores before and after treatment is less than 0.05. There was significant reduction in clinical symptoms having p value is 0.01 and hence it is clear that “Omachooranam” for the management of hemorrhoid the treatment was effective and significant.
Keywords: Oma chooranam,Internal hemorrhoids,Tachyspermum ammi powder, Siddha,
Bleeding piles,moolam.
{"title":"An open non randomized clinical trial to evaluate the effectiveness of Tachyspermum ammi powder - Oma chooranam in the management of moolam (Internal hemorrhoids) among out-patients attending Ayothidoss Pandithar Hospital, National Institute of Siddha, Chennai","authors":"Bharathy Kannan, Lakshmi Kantham T, Meena Kumari R","doi":"10.47552/ijam.v14i3.3738","DOIUrl":"https://doi.org/10.47552/ijam.v14i3.3738","url":null,"abstract":"Background: Hemorrhoid disease is the fourth leading out-patient gastrointestinal diagnosis in world wide. It arises from congestion of the internal and/or external venous plexuses around the anal canal.
 Aim: The aim of this study was to evaluate the therapeutic effectiveness of siddha herbal formulation Oma chooranam in the management of moolam (Internal Hemorrhoids) patients through proctoscopy and Hemorrhoid Symptom Score (HSS) before and after treatment.
 Materials and Methods: This study was an open non randomized clinical trial and it was was conducted after getting Institutional Ethical Committee clearance. Patients (N=10) diagnosed with moolam (internal haemorrhoids) using proctscopy results, were enrolled in the study over a period of 6 months (from February 2022 to August 2022). Each patient received 3grams of Oma chooranam mixed in warm water twice a day, for 24 days and patients were followed up for 2 months. The main outcome measure of this study was efficacy assessment, which was measured by using Haemorrhoid Symptom Severity scores(HSS Score) on Day-0 (baseline) and 25th day.
 Result and conclusion: Biostatistical p value using Wilcoxon signed rank test of HSS scores before and after treatment is less than 0.05. There was significant reduction in clinical symptoms having p value is 0.01 and hence it is clear that “Omachooranam” for the management of hemorrhoid the treatment was effective and significant.
 Keywords: Oma chooranam,Internal hemorrhoids,Tachyspermum ammi powder, Siddha,
 Bleeding piles,moolam.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135789902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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