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LEVELS OF PROCALCITONIN IN THE PATIENTS OF SEPSIS 败血症患者的降钙素原水平
Pub Date : 2024-02-29 DOI: 10.21474/ijar01/18288
Vinita Singh, Sneha Wadalkar
Sepsis, a life-threatening complication of an infection, resulting from release of cytokines in the bloodstream to fight an infection, ultimately triggering inflammation throughout the body. This can cause a cascade of changes that damage multiple organ systems, leading them to fail, sometimes even resulting in death.Crucial steps for a successful treatment and positive outcomes, are an early diagnosis and differentiation from non-infectious causes. PCT is biomarker that has diagnostic, therapeutic and prognostic significance. The study was undertaken to identify whether serum pro-calcitonin can act as a superior marker in septicemia. Material Method-This is prospective case control-pilot study.Total 60 subjects were included, Case group comprised of 30 IPD patients of sepsis, whereas 30 heathy individuals were included in control group. Levels of PCT, CRP levels and neutrophil count were analyzed in both the groups .PCT levels were analyzed by electrochemiluminescence method using commercially available kit & CRP levels by Nephelometry method respectively. Neutrophil counts were done on Sysmex five-part cell counter. Result- The levels of Neutrophils (%), PCT (ng/ml) and CRP (mg/L) were significantly high is study group with mean of 79.94 ± 16.9, 7.27 ± 18.6 and 64.2±49.9 respectively in study group with p value <0.001.CRP and PCT are similarly significant markers with co-relation coefficient of 0.518. Conclusion-Procalcitonin can be used as an inflammatory marker for sepsis with added significance of diagnostic as well as a prognostic marker.
败血症是一种危及生命的感染并发症,由血液中为抗感染而释放的细胞因子引起,最终引发全身炎症。要想成功治疗并取得积极疗效,关键步骤是早期诊断并与非感染性病因区分开来。PCT 是一种具有诊断、治疗和预后意义的生物标志物。本研究旨在确定血清降钙素原是否可作为脓毒血症的高级标志物。材料 方法--这是一项前瞻性病例对照试点研究,共纳入 60 名受试者,病例组包括 30 名脓毒症 IPD 患者,对照组包括 30 名健康人。两组患者的 PCT 水平、CRP 水平和中性粒细胞计数都进行了分析。PCT 水平采用电化学发光法(使用市售试剂盒)进行分析,CRP 水平则采用肾图法进行分析。中性粒细胞计数采用 Sysmex 五区细胞计数器。结果--研究组的中性粒细胞(%)、PCT(纳克/毫升)和CRP(毫克/升)水平明显偏高,平均值分别为79.94±16.9、7.27±18.6和64.2±49.9,P值<0.001。结论--降钙素原可作为脓毒症的炎症标志物,具有诊断和预后标志物的双重意义。
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引用次数: 0
LIFELONG LEARNING AND SOCIAL INCLUSION: AN ANALYSIS OF THE EFFECTS ON INDIVIDUAL EMPOWERMENT PROCESSES 终身学习与社会包容:对个人赋权进程的影响分析
Pub Date : 2024-02-29 DOI: 10.21474/ijar01/18299
Enrico Moch
The area of lifelong learning is becoming increasingly important both collectively and individually and is a key success factor for personal and social development. Awareness of lifelong learning also strengthens the possibility of increasing personal income and at the same time enabling a better quality of life. All of this leads to an improvement not only on an individual level, but also for society as a whole. Although lack of equitable educational opportunities to individuals may result into social inequalities, which require targeted measures to deal with these issues. The main objective of this research is to explain the relationship between lifelong learning and social inclusion. By assessing educational access and opportunities, the study aims to examine the impacts of lifelong learning on individual empowerment processes, and thereby address social inequalities in educational opportunities. This research adopts a comprehensive study design, in which a detailed literature review analysis with case studies will be considered. Several academic books, peer-reviewed journals, and other formal publications will be used for literature review, while official reports may be used to derive case studies. The thematic coding and content analysis will be used to analyse key trends, insights, and challenges identified through gathered qualitative data. As a whole, lifelong learning can become a tool to promote social inclusion by offering equitable educational opportunities to all population groups. Barriers to educational opportunities, such as ineffective division of lifelong learning and traditional education, financial constraints, geographical barriers, and more focus on certain category of workers, must be addressed.
终身学习对集体和个人都越来越重要,是个人和社会发展的关键成功因素。对终身学习的认识还有助于增加个人收入,同时提高生活质量。所有这一切不仅改善了个人的生活,也改善了整个社会的生活。虽然个人缺乏公平的教育机会可能会导致社会不平等,但需要采取有针对性的措施来解决这些问题。本研究的主要目的是解释终身学习与社会包容之间的关系。通过评估受教育的机会和途径,本研究旨在探讨终身学习对个人赋权过程的影响,从而解决教育机会方面的社会不平等问题。本研究采用综合研究设计,其中将考虑详细的文献综述分析和案例研究。文献综述将使用一些学术著作、同行评审期刊和其他正式出版物,而案例研究则可使用官方报告。专题编码和内容分析将用于分析通过收集的定性数据确定的主要趋势、见解和挑战。总体而言,终身学习可以成为促进社会包容的工具,为所有人群提供公平的教育机会。必须解决教育机会方面的障碍,如终身学习与传统教育划分不清、财务限制、地理障碍以及更加关注某类工人等。
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引用次数: 0
AUTOMEDICATION PAR LES INHIBITEURS DE LA POMPE A PROTONS CHEZ LE PERSONNEL DE SANTE 医护人员自行服用质子泵抑制剂的情况
Pub Date : 2024-02-29 DOI: 10.21474/ijar01/18346
L. Grihe, H. Ouaya, H. Meyiz, I. Mellouki
Les IPP sont devenus depuis quelques temps parmi les medicaments les plus prescrits en medecine generale, et prescrits dans de nombreuses indications pour leur efficacite,leur profil de tolerance mais aussi pour leur securite. Les effets secondaires et indesirables sont souvent ignores et du fait de leurs benefices ainsi les rendant des medicaments sur prescrits mais aussi avec des risques et effets indesirables et secondaires non negligeables. Cependant, leur accès libre leur donne la susceptibilite detre les medicaments les plus utilises en automedication. Notre etude avait pour objet devaluer la frequence et les modalites de lautomedication par les IPP chez le personnel de sante exerçant au sein de CHU Mohamed VI de Tanger. Pour cela nous avons mene une etude prospective descriptive transversale pour levaluer. Conflit dinteret: Pas de conflit.
一段时间以来,PPIs 因其疗效、耐受性和安全性而成为普通药物中处方最广泛的药物之一,用于多种适应症。这类药物的副作用和不良副作用往往被忽视,由于其疗效好,因此被过量处方,但也有很大的风险和不良副作用。然而,这些药物可以免费获得,这意味着它们很可能是最常见的自我药疗药物。我们的研究旨在评估丹吉尔穆罕默德六世医院医护人员自行服用 PPI 的频率和方法。为此,我们进行了一项前瞻性描述性横断面研究。利益冲突:无冲突。
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引用次数: 0
REACTIONAL IMPACT OF NICKEL SULPHATE HYDRATE ON THE HYDROPYROLYSIS FOR DIFFERENT OIL SHALE LAYERS FROM THE TARFAYA DEPOSIT (MOROCCO) 硫酸镍水合物对塔尔法亚矿床(摩洛哥)不同油页岩层的加氢分解的反应影响
Pub Date : 2024-02-29 DOI: 10.21474/ijar01/18274
A. Attaoui
Nickel catalysis has been studied for coal tars and graphite carbon to produce CH4 methane in the presence of hydrogen. Nickel forms mixed complexes with le g and bpycoline (P.F. Neson: 1988). In this work, we have focused on the mineral part formed mainly by calcite, dolomite, pyrite and other mineral compounds, with the aim of understanding the influence of nickel sulfide as an additive during the hydrotreatment of this mineral matrix from the Tarfaya (Morocco) oil shale under dynamic conditions. The techniques adopted in this study are true thermogravimetry (Red-Croft), calorimetry (DCE) coupled in Red-Croft, X-ray diffraction and dispersive X-ray diffraction coupled by scanning electron microscope. Carbonate decomposition activity was observed during this nickel sulfide addition, preventing in situ decomposition of NiSO4, 6H2O in the presence of hydrogen, and increasing conversion of calcite, dolomite, kaolinite and quartz.
已对镍催化煤焦油和石墨碳在氢气存在下产生 CH4 甲烷进行了研究。镍与 le g 和 bpycoline 形成混合络合物(P.F. Neson:1988 年)。在这项工作中,我们重点研究了主要由方解石、白云石、黄铁矿和其他矿物化合物形成的矿物部分,目的是了解在动态条件下对塔尔法亚(摩洛哥)油页岩的这种矿物基质进行加氢处理时,硫化镍作为添加剂的影响。本研究采用的技术包括热重仪(Red-Croft)、热量计(DCE)、X 射线衍射和扫描电子显微镜下的色散 X 射线衍射。在硫化镍添加过程中观察到了碳酸盐分解活动,阻止了 NiSO4, 6H2O 在氢气存在下的原位分解,提高了方解石、白云石、高岭石和石英的转化率。
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引用次数: 0
EFFECT OF LOW LEVEL LASER OF 650NM ON VIALBILITY OF PREVOTELLA INTERMEDIAWITH AND WITHOUT PHOTOSENSITISERS: AN IN VITRO STUDY 波长为 650nm 的低强度激光对含光敏剂和不含光敏剂的间盘尾丝菌生命力的影响:体外研究
Pub Date : 2024-02-29 DOI: 10.21474/ijar01/18354
M.M Dayakar, Mohammed Nihal Abbas Majeed, Apoorva Gurulingappa
Background: Prevotella intermedia is commonly associated with various forms of periodontal disease. Conventional treatment involves a combination of mechanical therapy and systemic antibiotics administration, which comes with its own set of challenges and disadvantages. An alternative treatment modality is low-level laser therapy with and without photosensitizers. Purpose: This study aimed to evaluate the effectiveness of low-level laser therapy with and without the use of photosensitizers, specifically Methylene blue and Toluidine blue, on the viability of Prevotella intermedia. Methods: The study utilized in vitro experiments to assess the impact of low-level laser therapy alone and in combination with photosensitizers on the viability of Prevotella intermedia. Results: The findings indicate that Methylene blue, when combined with low-level laser therapy, exhibits bactericidal effects similar to or greater than low-level laser therapy alone on Prevotella intermedia. Additionally, the use of Toluidine blue as a photosensitizer in combination with low-level laser therapy also led to a reduction in the viability of Prevotella intermedia, although it was not as effective as Methylene blue. Conclusion: Low-level laser therapy, particularly when combined with Methylene blue as a photosensitizer, shows promise as a potential treatment modality for controlling Prevotella intermedia in periodontal diseases.
背景:中前孢子菌通常与各种形式的牙周病有关。传统的治疗方法包括机械治疗和全身使用抗生素,但这两种方法都有各自的挑战和缺点。另一种治疗方法是使用或不使用光敏剂的低强度激光疗法。目的:本研究旨在评估使用或不使用光敏剂(特别是亚甲蓝和甲苯胺蓝)的低强度激光疗法对中间前牙菌活力的影响。研究方法该研究利用体外实验来评估低强度激光疗法单独使用或与光敏剂联合使用对中间普雷沃氏菌活力的影响。结果显示研究结果表明,亚甲基蓝与低强度激光疗法相结合,对中间普雷沃氏菌的杀菌效果与单独使用低强度激光疗法相似或更强。此外,将甲苯胺蓝作为光敏剂与低强度激光疗法结合使用,也能降低中间普雷沃氏菌的存活率,但效果不如甲苯胺蓝。结论低强度激光疗法,尤其是结合亚甲蓝作为光敏剂时,有望成为控制牙周病中间普雷沃氏菌的一种潜在治疗方式。
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引用次数: 0
STREE BEEJ AND ITS ROLE IN INFERTILITY - A CASE STUDY Stree beej 及其在不孕症中的作用 - 案例研究
Pub Date : 2024-02-29 DOI: 10.21474/ijar01/18352
Sumol Anand Pawar, Amardeep Madhukar Mamale
This case study explores the Ayurvedic concept of Stree Beej, emphasizing its pivotal role in addressing infertility. Examining the complex relationship between the doshas (Vata, Pitta, and Kapha) and Stree Beej, which is the female reproductive seed, the research explores imbalances that result in infertility. An in-depth analysis of a particular case clarifies the efficacy of Ayurvedic treatments, such as Shatavari, which are herbal therapies. The results highlight the need of reestablishing doshic balance in order to improve Stree Beej vitality and provide important new information on Ayurvedas comprehensive approach to treating infertility with customized remedies and lifestyle modifications.
本案例研究探讨了阿育吠陀的 "Stree Beej "概念,强调了它在解决不孕症方面的关键作用。本研究探讨了女性生殖种子 Stree Beej 与各种体质(Vata、Pitta 和 Kapha)之间的复杂关系,探讨了导致不孕不育的失衡问题。通过对一个特殊病例的深入分析,阐明了阿育吠陀疗法的疗效,如 Shatavari(一种草药疗法)。研究结果凸显了重建生殖平衡以提高 Stree Beej 活力的必要性,并为阿育吠陀通过定制疗法和生活方式调整来治疗不孕症的综合方法提供了重要的新信息。
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引用次数: 0
LARYNGEAL PLASMACYTOMA IN KAHLERS DISEASE: A CASE REPORT 卡勒斯病中的喉浆细胞瘤:病例报告
Pub Date : 2024-02-29 DOI: 10.21474/ijar01/18335
A. Ben Ameur El Youbi, A. Arioua, M. Ridal, N. Benmansour, A. Oudidi, N. Hammas, MN. EL Alami El Amine
Multiple myeloma or Kahlers disease is a malignant hematological disorder due to a monoclonal plasma cell proliferation primarily invading the hematopoietic bone marrow. Extra-medullar involvement occurs in 18% of patients with multiple myeloma. Laryngeal Localization remains rare and has been described in a few cases after a literature review.We report the case of a 44-year-old woman who presented an inspiratory dyspnea caused by a laryngeal tumor. The pathological study and bone marrow examination confirmed the laryngeal localization of multiple myeloma. Treatment consisted of chemotherapy with good clinical outcomes over a 2-year follow-up period.
多发性骨髓瘤或卡勒氏病是一种恶性血液病,由主要侵犯造血骨髓的单克隆浆细胞增生引起。18%的多发性骨髓瘤患者会出现髓外受累。我们报告了一例 44 岁女性患者的病例,她因喉部肿瘤导致吸气性呼吸困难。病理检查和骨髓检查证实,该患者的喉部定位为多发性骨髓瘤。治疗包括化疗,两年的随访取得了良好的临床效果。
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引用次数: 0
LE LECTEUR MODELE DE SAMI TCHAK le lecteur modele de sami tchak
Pub Date : 2024-02-29 DOI: 10.21474/ijar01/18295
Satra Baguissoga
This article attempts to reconstruct the image of the model reader postulated in the writing of Togolese novelist Sami Tchak. To do this, he relies on the poetic of novel and sociology of reading in order to examine the aesthetic of creation in the novelist and to establish the appropriate conditions for reception of this works. The analysis of the romantic plots shows a tight focus around a nightmarish universe dominates by decay and voluptuousness, without totems or taboos, where the characters are neither angels nor beasts, but simply ready to corrupts themselves in order to be happy. It highlights the power of the authors view of the world, that is to say his assumed subjectivity, which he honed from his childhood in his fathers forge, then in middle age at during his incessant travels to the four corners of the world. Thus, the model reader of Sami Tchak must above all allow himself to never shy away from taboos of any kind. He must be ready to wander the cities, to meet myriads of endearing and, very often, eccentric characters wandering sometimes in the upscale neighborhoods, sometimes in the disreputable slums of the suburbs of the world. Because, ultimately, Sami Tchaks texts are strongly colored by didacticism, freedom of thought and spirit. They demonstrate a real intention to share knowledge of an encyclopedic nature to make readers more competent than they are.
本文试图重建多哥小说家萨米-特查克笔下的模范读者形象。为此,他以小说诗学和阅读社会学为基础,研究小说家的创作美学,并为作品的接受创造适当的条件。对浪漫主义情节的分析表明,小说紧紧围绕着一个以腐朽和淫荡为主导、没有图腾和禁忌的梦魇般的世界,小说中的人物既不是天使也不是野兽,他们只是为了获得幸福而随时准备腐化自己。这凸显了作者世界观的力量,也就是他假定的主观性,这是他从小在父亲的锻造厂里磨练出来的,到了中年又在不停地周游世界的过程中磨练出来的。因此,萨米-恰克的模范读者首先必须让自己从不回避任何禁忌。他必须做好准备,在城市中游荡,遇到无数可爱的、常常是古怪的人物,他们时而游荡在高档社区,时而游荡在世界郊区不光彩的贫民窟。归根结底,萨米-恰克思的作品带有强烈的说教、思想和精神自由的色彩。它们展示了一种真正的意图,即分享百科全书式的知识,让读者比自己更有能力。
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引用次数: 0
ASSOCIATION OF EUTHYROID TYPE 2 DIABETES MELLITUS WITH HEMOGLOBIN AND SERUM BILIRUBIN LEVELS RELATING TO GLYCEMIC CONTROL - A RETROSPECTIVE STUDY 甲状腺功能正常的 2 型糖尿病患者血红蛋白和血清胆红素水平与血糖控制的关系 - 一项回顾性研究
Pub Date : 2024-02-29 DOI: 10.21474/ijar01/18297
Jayanthi Rajendran, Priyanka A.
Background: Diabetes, along with its comorbidities, may increase the risk of anaemia by lowering iron absorption. In diabetic patients, thyroid illness was 14.7% prevalent. In 13% of T2DM patients, subclinical hypothyroidism was the most common thyroid condition. Diabetes glucose metabolism may be impacted by thyroid dysfunction, and variations in blood TSH have been linked to variations in glycatedhaemoglobin. Methodology: Retrospective study analysis of euthyroid type 2 diabetic patients who had attended the OPD in the department of General Medicine. The hospital records (case history from MRD) were used as the sources of information by following proper procedure in obtaining the same. Collection of data for a period of four years with Type 2 diabetes (FBS>126) and who did not possess any obvious clinical manifestations of thyroid disease was included for the study group. Results: PBS, HbA1C, LDL, TSH are highly significant with Fasting blood sugar with(p=0.00). FBS, RBC are highly significant with HbA1C (p=0.00). Uric acid, cholesterol,directbilirubin,haemoglobinishighlysignificantwithbilirubin(p=0.00).whereascholesterol, total billirubin are highly significant with haemoglobin (p=0.00). Hb showedpositive association with FT4. TAG, VLDL, Globulin showed negative association with FBS.HbisnegativelyassociatedwithTotalbilirubin.Cholesterolexhibitsstrongnegativeassociation with Hemoglobin (HbA1c ≥7). TSHwere associated with FBS. Direct bilirubinexhibits positive association with FBS and TotalCholesterol(HbA1c ≤7). Conclusion: Our study results outcome could be concluded that the thyroid status, haemoglobinandCBCcouldbeusefultoolforT2DMpatients.
背景:糖尿病及其并发症会降低铁的吸收,从而增加贫血的风险。在糖尿病患者中,甲状腺疾病的发病率为 14.7%。在 13% 的 T2DM 患者中,亚临床甲状腺功能减退症是最常见的甲状腺疾病。甲状腺功能障碍可能会影响糖尿病的糖代谢,血液中促甲状激素的变化与糖化血红蛋白的变化有关。研究方法对在全科医学科门诊就诊的甲状腺功能正常的 2 型糖尿病患者进行回顾性研究分析。通过适当程序获取医院病历(MRD 病史)作为信息来源。研究组收集了四年内患有 2 型糖尿病(FBS>126)且无任何明显甲状腺疾病临床表现的患者的数据。研究结果PBS、HbA1C、低密度脂蛋白、促甲状腺激素与空腹血糖的关系非常显著(P=0.00)。FBS 和 RBC 与 HbA1C 的关系非常显著(P=0.00)。尿酸、胆固醇、直接胆红素、血红蛋白与胆红素呈高度显著性(P=0.00),而胆固醇、总胆红素与血红蛋白呈高度显著性(P=0.00)。血红蛋白与 FT4 呈正相关。胆固醇与血红蛋白(HbA1c≥7)呈强负相关。促甲状腺激素与 FBS 相关。直接胆红素与 FBS 和总胆固醇(HbA1c ≥‰¤7)呈正相关。结论我们的研究结果表明,甲状腺状态、血红蛋白和全血细胞计数可作为T2DM患者的有用工具。
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引用次数: 0
IMPACT DES FUMURES ORGANIQUE ET MINERALE SUR LES PARAMETRES AGRONOMIQUES DU MIL (PENNISETUM GLAUCUM (L.) R. BR.) A TARNA, NIGER 有机肥和矿物肥对小米(Pinnisetum glaucum (L.) R. BR.)农艺学参数的影响塔纳,尼日尔
Pub Date : 2024-02-29 DOI: 10.21474/ijar01/18331
Abarchi Idrissa, Ado Salifou Hadiza, Issoufou Garba Mahaman Bachir, Boubacar Kimba Ibrahim, K. issa
Millet, Pennisetum glaucum (L.) R. Br. is the excellent crop adapted to the particular production conditions of the Sahel. However climatic hazards and inherent low soil fertility reduce millet yield. Hence, this study aims to evaluate the impact of organic and mineral fertilizers on agronomic parameters of millet. The trial was conducted at the experimental station of the regional agricultural research center of Tarna (Maradi). The experimental design is a randomized complete block with 12 treatments replicated three times. The plant material used is SOSAT C88. The parameters measured are emergence rate, tillering bolting and millet yield. Results analysis shows that the use of organic and mineral fertilizers significantly affect tillering, bolting and millet yield. The results obtained show that the application of organic and mineral fertilizers improves the agronomic parameters of millet.
小米(Pennisetum glaucum (L.) R. Br.)是适应萨赫勒地区特殊生产条件的优良作物。然而,气候灾害和固有的低土壤肥力降低了小米的产量。因此,本研究旨在评估有机肥和矿物肥对小米农艺参数的影响。试验在塔尔纳(马拉迪)地区农业研究中心的实验站进行。试验设计为随机完全区组,共有 12 个处理,重复三次。使用的植物材料是 SOSAT C88。测量参数为出苗率、分蘖力和小米产量。结果分析表明,有机肥和矿物肥的使用对分蘖、结实率和小米产量有显著影响。结果表明,施用有机肥和矿物质肥料可改善小米的农艺参数。
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引用次数: 0
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International Journal of Advanced Research
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