Oluwatobi Emmanuel Adesida, Temitope Janet Owolawi, Oyedunni Sola Arulogun
Self-harm is a major public health concern affecting thousands of women although it is an under-reported and neglected aspect of maternal health particularly in developing countries where there is a paucity of evidence regarding self-harm and it is rarely given attention. This study was a cross sectional quantitative study carried out to investigate the knowledge, attitude and perception of self-harm in pregnancy among 369 women attending antenatal clinics in a government owned hospital in southwest Nigeria. Respondents were selected using multi-stage sampling technique from ante natal clinics with the aid of semi-structured questionnaire to elicit information on their socio-demographic, knowledge, perception, and their attitude towards self-harm. Data were entered using SPSS version 25 and were analysed using descriptive and inferential Chi-square statistics at p =0.05. Respondent’s knowledge on self-harm in pregnancy was measured on 7 items and 7-point scale. Knowledge score of <2 was rated as poor and ≥7 was rated as good. Perception of self-harm in pregnancy was measured on 16 items and 16-point scale, score <8 was rated as negative and scores ≥8 was rated as positive. While respondents’ attitude toward self-harm was measured on 11 items and 11-point scale, score <6 was rated as negative and scores ≥6 as positive. Most respondents (85.4%) had a good knowledge of self-harm in pregnancy, good perception of (79.1%) and positive attitude of (85.9%). There should be public awareness and education campaigns on early detection, screening and counselling of pregnant women on the effect and risks of self-harm in pregnancy. Keywords: Knowledge, Attitude, Perception, Self-harm, Pregnancy, Hospital, Antenatal
{"title":"Knowledge, Attitude and Perception of Self-Harm in Pregnancy Among Women Attending Ante-Natal Clinics in South-Western Nigeria","authors":"Oluwatobi Emmanuel Adesida, Temitope Janet Owolawi, Oyedunni Sola Arulogun","doi":"10.52403/ijrr.20231108","DOIUrl":"https://doi.org/10.52403/ijrr.20231108","url":null,"abstract":"Self-harm is a major public health concern affecting thousands of women although it is an under-reported and neglected aspect of maternal health particularly in developing countries where there is a paucity of evidence regarding self-harm and it is rarely given attention. This study was a cross sectional quantitative study carried out to investigate the knowledge, attitude and perception of self-harm in pregnancy among 369 women attending antenatal clinics in a government owned hospital in southwest Nigeria. Respondents were selected using multi-stage sampling technique from ante natal clinics with the aid of semi-structured questionnaire to elicit information on their socio-demographic, knowledge, perception, and their attitude towards self-harm. Data were entered using SPSS version 25 and were analysed using descriptive and inferential Chi-square statistics at p =0.05. Respondent’s knowledge on self-harm in pregnancy was measured on 7 items and 7-point scale. Knowledge score of <2 was rated as poor and ≥7 was rated as good. Perception of self-harm in pregnancy was measured on 16 items and 16-point scale, score <8 was rated as negative and scores ≥8 was rated as positive. While respondents’ attitude toward self-harm was measured on 11 items and 11-point scale, score <6 was rated as negative and scores ≥6 as positive. Most respondents (85.4%) had a good knowledge of self-harm in pregnancy, good perception of (79.1%) and positive attitude of (85.9%). There should be public awareness and education campaigns on early detection, screening and counselling of pregnant women on the effect and risks of self-harm in pregnancy. Keywords: Knowledge, Attitude, Perception, Self-harm, Pregnancy, Hospital, Antenatal","PeriodicalId":13809,"journal":{"name":"International Journal of Current Research and Review","volume":"18 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135872984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dhara Santosh Agnihotri, Anjali R Bhise, Krutarth Purnendu Shah
Spasmodic pelvic floor muscles can occur due to multiple reasons like stress, anxiety, recurrent urinary tract infection. The pelvic floor dysfunctions due to hypertonus pelvic floor muscles can be Vaginismus, dyspareunia, chronic pelvic pain, urinary symptoms like dysuria, incomplete voiding, lower abdominal pain associated with bladder filling, hypertonic pelvic floor muscles can also lead to issues with constipation, pelvic dyssynergia etc. The prevalence of Vaginismus and dyspareunia is very high. Yet there is no single tool which is designed to assess the pelvic floor relaxation ability. Vlosum is the world’s first device which can test and improve vaginal opening (through relaxation of pelvic floor muscles). The outcome measure taken are FSFI – Female Sexual Function Index, NPRS – Numeric Pain Rating Scale, self-reported question for anxiety about first time penetration and Vlosum. The study duration was of 18 months and 1184 women were evaluated. The participants were divided into 3 groups Group A – Vaginismus, Group B – Dyspareunia and Group C – Anxiety of first-time penetration. The data of all the outcome measure were analyzed. It can be concluded that Vlosum is a reliable and valid tool to test vaginal opening. Keywords: Vaginismus, Dyspareunia, First-time Anxiety, Vlosum
{"title":"Validity & Reliability of Vlosum (Het’s Device - to Instantly Test Vaginal Opening) Test the Vaginal Opening","authors":"Dhara Santosh Agnihotri, Anjali R Bhise, Krutarth Purnendu Shah","doi":"10.52403/ijrr.20231111","DOIUrl":"https://doi.org/10.52403/ijrr.20231111","url":null,"abstract":"Spasmodic pelvic floor muscles can occur due to multiple reasons like stress, anxiety, recurrent urinary tract infection. The pelvic floor dysfunctions due to hypertonus pelvic floor muscles can be Vaginismus, dyspareunia, chronic pelvic pain, urinary symptoms like dysuria, incomplete voiding, lower abdominal pain associated with bladder filling, hypertonic pelvic floor muscles can also lead to issues with constipation, pelvic dyssynergia etc. The prevalence of Vaginismus and dyspareunia is very high. Yet there is no single tool which is designed to assess the pelvic floor relaxation ability. Vlosum is the world’s first device which can test and improve vaginal opening (through relaxation of pelvic floor muscles). The outcome measure taken are FSFI – Female Sexual Function Index, NPRS – Numeric Pain Rating Scale, self-reported question for anxiety about first time penetration and Vlosum. The study duration was of 18 months and 1184 women were evaluated. The participants were divided into 3 groups Group A – Vaginismus, Group B – Dyspareunia and Group C – Anxiety of first-time penetration. The data of all the outcome measure were analyzed. It can be concluded that Vlosum is a reliable and valid tool to test vaginal opening. Keywords: Vaginismus, Dyspareunia, First-time Anxiety, Vlosum","PeriodicalId":13809,"journal":{"name":"International Journal of Current Research and Review","volume":"17 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135872986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Deep Vein Thrombosis (DVT) occurs in stroke with an incidence varying from 10-75%, depending on the diagnostic method and time of evaluation. Platelets play important role in the pathogenesis of thromboembolism. Large size platelets are more metabolically and enzymatically active also hemostatically more reactive and prone to the development of thrombosis. This study aims to determine the association between platelet index and the occurrence of DVT in patients with acute ischemic stroke. Method: Prospective study with a total of 42 samples acute ischemic stroke patients who were treated ≤ 3 days in the stroke corner of RSUP. H Adam Malik Medan. Compression ultrasonography to diagnose DVT was performed on the lower extremities. Platelet indices assessed were mean platelet volume (MPV), platelet volume distribution width (PDW), and plateletcrit (PCT) based on the results of a complete blood test on admission. Results: The mean age was 59.7 years with male gender as much as 66.7%. The majority of research subjects had a history of hypertension (42.9%) The mean body mass index was 28, 18 kg/mm2. 97.6% were found to have asymptomatic DVT with Well's score of 1 (moderate probability of DVT occurrence). 54.8% of the study subjects with positive DVT results based on compression ultrasound results. There is an association between increased MPV and the incidence of DVT in acute ischemic stroke patients (p = 0.002). Conclusion: There is an association between an increase in MPV value and the incidence of DVT in acute ischemic stroke patients. Keywords: Platelet Index, Deep Vein Thrombosis, Acute Ischemic Stroke, Mean Platelet Volume, Platelet Distribution Width, Plateletcrit
深静脉血栓形成(DVT)发生在脑卒中中，其发生率从10-75%不等，取决于诊断方法和评估时间。血小板在血栓栓塞的发病机制中起重要作用。大尺寸的血小板代谢和酶活性更高，止血反应也更强，更容易形成血栓。本研究旨在探讨急性缺血性脑卒中患者血小板指数与DVT发生的关系。方法:前瞻性研究共42例急性缺血性脑卒中患者，均在RSUP脑卒中角治疗≤3天。H Adam Malik Medan。下肢行压缩超声诊断深静脉血栓。血小板指标评估为平均血小板体积(MPV)、血小板体积分布宽度(PDW)和血小板电积(PCT)，基于入院时全血检查结果。结果:平均年龄59.7岁，男性占66.7%。大多数研究对象有高血压病史(42.9%)，平均体重指数为28.18 kg/mm2。97.6%的患者无症状深静脉血栓形成，Well's评分为1分(发生DVT的概率中等)。54.8%的研究对象根据压缩超声结果为DVT阳性。急性缺血性脑卒中患者MPV升高与DVT发生率之间存在相关性(p = 0.002)。结论:急性缺血性脑卒中患者MPV值升高与DVT发生率存在相关性。关键词:血小板指数，深静脉血栓形成，急性缺血性卒中，平均血小板体积，血小板分布宽度，血小板电位
{"title":"The Association of Platelet Index with Event of Deep Vein Thrombosis in Acute Ischemic Stroke Patients at Rumah Sakit Umum Pusat Haji Adam Malik Medan","authors":"Noviari Liara Justitia, Dairion Gatot, Heny Syahrini Lubis","doi":"10.52403/ijrr.20231102","DOIUrl":"https://doi.org/10.52403/ijrr.20231102","url":null,"abstract":"Introduction: Deep Vein Thrombosis (DVT) occurs in stroke with an incidence varying from 10-75%, depending on the diagnostic method and time of evaluation. Platelets play important role in the pathogenesis of thromboembolism. Large size platelets are more metabolically and enzymatically active also hemostatically more reactive and prone to the development of thrombosis. This study aims to determine the association between platelet index and the occurrence of DVT in patients with acute ischemic stroke. Method: Prospective study with a total of 42 samples acute ischemic stroke patients who were treated ≤ 3 days in the stroke corner of RSUP. H Adam Malik Medan. Compression ultrasonography to diagnose DVT was performed on the lower extremities. Platelet indices assessed were mean platelet volume (MPV), platelet volume distribution width (PDW), and plateletcrit (PCT) based on the results of a complete blood test on admission. Results: The mean age was 59.7 years with male gender as much as 66.7%. The majority of research subjects had a history of hypertension (42.9%) The mean body mass index was 28, 18 kg/mm2. 97.6% were found to have asymptomatic DVT with Well's score of 1 (moderate probability of DVT occurrence). 54.8% of the study subjects with positive DVT results based on compression ultrasound results. There is an association between increased MPV and the incidence of DVT in acute ischemic stroke patients (p = 0.002). Conclusion: There is an association between an increase in MPV value and the incidence of DVT in acute ischemic stroke patients. Keywords: Platelet Index, Deep Vein Thrombosis, Acute Ischemic Stroke, Mean Platelet Volume, Platelet Distribution Width, Plateletcrit","PeriodicalId":13809,"journal":{"name":"International Journal of Current Research and Review","volume":"40 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135873562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Entrepreneurship education plays a very important role in preparing the younger generation to face the dynamics of modern business. In order to meet these demands, the focus of this research is the development of the Problem-Based Instruction (PBI) Learning Model in the subject of Creative Entrepreneurship Products at the Vocational High School (SMK) level. The aim of this research is to examine the effectiveness of PBI in improving students' entrepreneurial competence and business creativity. The method in this research is the ADDIE development method with research subjects as vocational school students. In the introductory stage, the importance of entrepreneurial competence and business creativity in the era of globalization and economic transformation is emphasized. The Entrepreneurship Creative Products subject at SMK offers an ideal platform to develop these skills. The PBI model was chosen because it emphasizes student-centered learning and contextual problem solving. Using a development research approach, this research involves the stages of problem definition, model design, material development, implementation and evaluation. It is hoped that the results of this research can contribute to the development of a learning model that combines entrepreneurial competence and business creativity through the PBI approach. Through the application of the PBI Model to the Creative Entrepreneurship Products subject, it is hoped that students will be better prepared to face future business challenges with broader insight and stronger skills. Keywords: problem based instruction, entrepreneurial competence, business creativity
{"title":"Developing a Problem Based Instruction Learning Model in Creative Entrepreneurship Product Subject to Achieve Entrepreneurial Competency and Business Creativity","authors":"Dwi Sumarsih, Forijati ., Sugiono .","doi":"10.52403/ijrr.20231107","DOIUrl":"https://doi.org/10.52403/ijrr.20231107","url":null,"abstract":"Entrepreneurship education plays a very important role in preparing the younger generation to face the dynamics of modern business. In order to meet these demands, the focus of this research is the development of the Problem-Based Instruction (PBI) Learning Model in the subject of Creative Entrepreneurship Products at the Vocational High School (SMK) level. The aim of this research is to examine the effectiveness of PBI in improving students' entrepreneurial competence and business creativity. The method in this research is the ADDIE development method with research subjects as vocational school students. In the introductory stage, the importance of entrepreneurial competence and business creativity in the era of globalization and economic transformation is emphasized. The Entrepreneurship Creative Products subject at SMK offers an ideal platform to develop these skills. The PBI model was chosen because it emphasizes student-centered learning and contextual problem solving. Using a development research approach, this research involves the stages of problem definition, model design, material development, implementation and evaluation. It is hoped that the results of this research can contribute to the development of a learning model that combines entrepreneurial competence and business creativity through the PBI approach. Through the application of the PBI Model to the Creative Entrepreneurship Products subject, it is hoped that students will be better prepared to face future business challenges with broader insight and stronger skills. Keywords: problem based instruction, entrepreneurial competence, business creativity","PeriodicalId":13809,"journal":{"name":"International Journal of Current Research and Review","volume":"39 14","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135873411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Moyamoya disease is a chronic cerebrovascular disorder characterized by progressive narrowing of the intracranial portions of the distal internal carotid artery, the initial proximal components of the middle cerebral artery, anterior cerebral artery, and posterior cerebral artery. Moyamoya disease can manifest as a stroke in young adult. Methods: This report presents a young female patient with Moyamoya disease in Siloam Hospital Denpasar, Bali, Indonesia, diagnosed using MRI and Digital Subtraction Angiography. Case Report: A 29-year-old woman with recurrent stroke, presented with right-side hemiparesis, urinary incontinence, disinhibition syndrome, hypertension, and a history of left hemiparesis from a previous stroke. The MRI brain showed hyperintensity throughout the sulci (ivy sign) in the bilateral frontoparietal with acute infarct in the left frontomedial region, chronic infarct in right frontomedial, occlusion of bilateral carotid arteries (supraclinoid segment), bilateral MCA and ACA. The cerebral DSA study showed stenosis in the right ICA, stenosis in the M1-M2 junction with poor collateral to ACA territory with a puff of smoke appearance, occlusion in the left ICA (supraclinoid segment), and severe stenosis in M1. The patient had undergone direct bypass in the right MCA and right superficial temporal artery. Unfortunately, the bypass did not succeed because of infection of the bypass site and the patient got oral medication with a single antiplatelet (asetosal) and angiotensin receptor blocker (valsartan). Discussion: Moyamoya disease is a rare chronic cerebrovascular disorder that can manifest as an ischaemic stroke in young adult. This patient had a recurrent ischaemic stroke due to Moyamoya disease. According to a global multicenter stroke database, 90% of Moyamoya disease patients initially presented with an ischemic stroke, 7.5% with a transient ischemic attack, and 2.5% with a hemorrhagic stroke. DSA showed that the intracranial collateral system failed to fulfill the demand for brain circulation when the stroke occurred. The patient had failure to grow collateral after direct bypass surgery from the right superficial temporal artery to MCA and single oral antiplatelet as a secondary prevention for ischaemic stroke. Conclusion: Moyamoya disease is a rare disease that needs further studies for its treatment to halt the progression and prevent secondary complications. Young patients with ischaemic stroke needed to be asses with brain MRI, MRA, and DSA to evaluate the etiology of ischaemic stroke. Keywords: Moyamoya disease, Digital Substraction Angiography,ischaemic stroke
{"title":"Recurrent Stroke in Young Adult as a Manifestation of Moyamoya Disease: Case Report","authors":"Edwin Pranata Laban, Kumara Tini, Nyoman Angga Krishna Pramana","doi":"10.52403/ijrr.20231103","DOIUrl":"https://doi.org/10.52403/ijrr.20231103","url":null,"abstract":"Background: Moyamoya disease is a chronic cerebrovascular disorder characterized by progressive narrowing of the intracranial portions of the distal internal carotid artery, the initial proximal components of the middle cerebral artery, anterior cerebral artery, and posterior cerebral artery. Moyamoya disease can manifest as a stroke in young adult. Methods: This report presents a young female patient with Moyamoya disease in Siloam Hospital Denpasar, Bali, Indonesia, diagnosed using MRI and Digital Subtraction Angiography. Case Report: A 29-year-old woman with recurrent stroke, presented with right-side hemiparesis, urinary incontinence, disinhibition syndrome, hypertension, and a history of left hemiparesis from a previous stroke. The MRI brain showed hyperintensity throughout the sulci (ivy sign) in the bilateral frontoparietal with acute infarct in the left frontomedial region, chronic infarct in right frontomedial, occlusion of bilateral carotid arteries (supraclinoid segment), bilateral MCA and ACA. The cerebral DSA study showed stenosis in the right ICA, stenosis in the M1-M2 junction with poor collateral to ACA territory with a puff of smoke appearance, occlusion in the left ICA (supraclinoid segment), and severe stenosis in M1. The patient had undergone direct bypass in the right MCA and right superficial temporal artery. Unfortunately, the bypass did not succeed because of infection of the bypass site and the patient got oral medication with a single antiplatelet (asetosal) and angiotensin receptor blocker (valsartan). Discussion: Moyamoya disease is a rare chronic cerebrovascular disorder that can manifest as an ischaemic stroke in young adult. This patient had a recurrent ischaemic stroke due to Moyamoya disease. According to a global multicenter stroke database, 90% of Moyamoya disease patients initially presented with an ischemic stroke, 7.5% with a transient ischemic attack, and 2.5% with a hemorrhagic stroke. DSA showed that the intracranial collateral system failed to fulfill the demand for brain circulation when the stroke occurred. The patient had failure to grow collateral after direct bypass surgery from the right superficial temporal artery to MCA and single oral antiplatelet as a secondary prevention for ischaemic stroke. Conclusion: Moyamoya disease is a rare disease that needs further studies for its treatment to halt the progression and prevent secondary complications. Young patients with ischaemic stroke needed to be asses with brain MRI, MRA, and DSA to evaluate the etiology of ischaemic stroke. Keywords: Moyamoya disease, Digital Substraction Angiography,ischaemic stroke","PeriodicalId":13809,"journal":{"name":"International Journal of Current Research and Review","volume":"40 15","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135873554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/Objective: Multiple Antipsychotics Therapy promote obesity and insulin resistance. This study aimed to describe a T2DM patient with extrapyramidal symptoms and hyperglycemia who was also on several antipsychotic therapies and to determine whether omission of all antipsychotics along with modification of antidiabetic therapy led to better glycemic control. Case Report: An uncontrolled T2DM female subject presented with tremor in both hands as well as in the right corner of her lips. She also having comorbid hypertension and hypothyroidism. On examination, she showed no signs of pallor, icterus, clubbing, cyanosis or edema. Central nervous system examination revealed a GCS of 15 and neurological examinations including motor and sensory responses were unremarkable in Nerve Conduction Study and MRI. her blood glucose levels showed poorly controlled diabetes (HbA1C – 9.5%, FBS – 278mg/dl, PPBS – 234mg/dl) in spite of taking OHAs. Her initial treatment plan included omission of all antipsychotics and reduction in dose of glimepiride to 4mg. This led to a drastic fall in the blood glucose levels. Her CBG levels were between 100mg/dl- 150 mg/dl. Soon after this, the dose of metformin was reduced to 1000mg, vildagliptin was omitted and a SGLT-2 inhibitor was added. This caused gradual improvement in her symptoms and subsequently the blood sugar levels and blood pressure were also within acceptable limits. Discussion: Diabetes and hyperglycaemic emergencies are linked to APDs. There may be several processes that mediate this. In insulin-sensitive cells such muscle cells, hepatocytes, and adipocytes, APDs can block the insulin signalling pathway, resulting in insulin resistance. When choosing a course of treatment, one must consider this elevated risk. Conclusion: Patients receiving multiple antipsychotics therapy are more likely to experience negative metabolic alterations. This case findings also highlight the importance of glycemic control in patients with acute or subacute onset movement disorders, irrespective of their past glycemic status. Keywords: Multiple Antipsychotics Therapy, insulin resistance, T2DM patient, extrapyramidal symptoms, hyperglycemia.
{"title":"Extrapyramidal Symptoms and Insulin Resistance in a Patient on Multiple Antipsychotics Therapy","authors":"Rishad Ahmed, Devangana Roy","doi":"10.52403/ijrr.20231105","DOIUrl":"https://doi.org/10.52403/ijrr.20231105","url":null,"abstract":"Background/Objective: Multiple Antipsychotics Therapy promote obesity and insulin resistance. This study aimed to describe a T2DM patient with extrapyramidal symptoms and hyperglycemia who was also on several antipsychotic therapies and to determine whether omission of all antipsychotics along with modification of antidiabetic therapy led to better glycemic control. Case Report: An uncontrolled T2DM female subject presented with tremor in both hands as well as in the right corner of her lips. She also having comorbid hypertension and hypothyroidism. On examination, she showed no signs of pallor, icterus, clubbing, cyanosis or edema. Central nervous system examination revealed a GCS of 15 and neurological examinations including motor and sensory responses were unremarkable in Nerve Conduction Study and MRI. her blood glucose levels showed poorly controlled diabetes (HbA1C – 9.5%, FBS – 278mg/dl, PPBS – 234mg/dl) in spite of taking OHAs. Her initial treatment plan included omission of all antipsychotics and reduction in dose of glimepiride to 4mg. This led to a drastic fall in the blood glucose levels. Her CBG levels were between 100mg/dl- 150 mg/dl. Soon after this, the dose of metformin was reduced to 1000mg, vildagliptin was omitted and a SGLT-2 inhibitor was added. This caused gradual improvement in her symptoms and subsequently the blood sugar levels and blood pressure were also within acceptable limits. Discussion: Diabetes and hyperglycaemic emergencies are linked to APDs. There may be several processes that mediate this. In insulin-sensitive cells such muscle cells, hepatocytes, and adipocytes, APDs can block the insulin signalling pathway, resulting in insulin resistance. When choosing a course of treatment, one must consider this elevated risk. Conclusion: Patients receiving multiple antipsychotics therapy are more likely to experience negative metabolic alterations. This case findings also highlight the importance of glycemic control in patients with acute or subacute onset movement disorders, irrespective of their past glycemic status. Keywords: Multiple Antipsychotics Therapy, insulin resistance, T2DM patient, extrapyramidal symptoms, hyperglycemia.","PeriodicalId":13809,"journal":{"name":"International Journal of Current Research and Review","volume":"40 13","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135873556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The administration of antibiotics in animal surgery and animal feed is a widely accepted practice intended to mitigate infection risks. Using antibiotics in animals is one of the most effective treatments available. However, when antibiotics are used imprudently can lead to severe consequences for animal health and may affect the ecosystem in many ways. This literature review aims to assess the effects of antibiotic use in animal surgery and animal feeding. The review explores the associated risks and benefits. This review aims to present an overview of the impact of antibiotics on animals in both surgical and feeding ways. Including the advantages and disadvantages that affect animals and the environment. To benefit those who are interested in veterinary or antibiotics administration Keywords: Antibiotics, Animal surgery, Animal feed, Animal Health, Veterinary medicine, Livestock
{"title":"The Impact of Antibiotic Use on Animal Surgery and Animal Feed: A Review of the Relevant Literature","authors":"Tharinee Mahateeranont","doi":"10.52403/ijrr.20231114","DOIUrl":"https://doi.org/10.52403/ijrr.20231114","url":null,"abstract":"The administration of antibiotics in animal surgery and animal feed is a widely accepted practice intended to mitigate infection risks. Using antibiotics in animals is one of the most effective treatments available. However, when antibiotics are used imprudently can lead to severe consequences for animal health and may affect the ecosystem in many ways. This literature review aims to assess the effects of antibiotic use in animal surgery and animal feeding. The review explores the associated risks and benefits. This review aims to present an overview of the impact of antibiotics on animals in both surgical and feeding ways. Including the advantages and disadvantages that affect animals and the environment. To benefit those who are interested in veterinary or antibiotics administration Keywords: Antibiotics, Animal surgery, Animal feed, Animal Health, Veterinary medicine, Livestock","PeriodicalId":13809,"journal":{"name":"International Journal of Current Research and Review","volume":"19 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135873087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study mentions the problem of determining optimal placements and sizes for capacitor banks by comparing different schemes that allow implemented buses at both high and low voltage side, only high voltage side or low voltage side of transformers in distribution systems. Criterions evaluated for each scheme are active and reactive power losses in whole system, voltage value at all buses, installation and operation cost and accumulative profit saving. Standard with and without transformer branches in distribution systems and Newton-Raphson method are introduced to make clear about the way to analyze power flows in whole system. Optimal placements and sizes for capacitor banks are determined by using a proposed algorithm and optimal capacitor placement tool in ETAP software. Simulation results can help to show the comparisons, evaluations and make decision about optimal capacitor placements and sizes. The contribution shows the best scheme that install capacitors at low voltage side of transformers because it has the lowest implemented capacity, highest economic factors while voltage quality is always in allowable range. Achieved results can be applied in any distribution system, help managers have overall review and decide optimal placements and sizes for capacitor banks. Keywords: Capacitor bank, OCP Tool, ETAP software, Optimal placement, Optimal size, Voltage quality, Optimal cost.
{"title":"Analysis of the Effect of Capacitor Placements at High and Low Voltage Transformer Sides as Voltage Profile and Total Cost in Distribution Systems","authors":"Nguyen Thi Thanh Thuy","doi":"10.52403/ijrr.20231112","DOIUrl":"https://doi.org/10.52403/ijrr.20231112","url":null,"abstract":"This study mentions the problem of determining optimal placements and sizes for capacitor banks by comparing different schemes that allow implemented buses at both high and low voltage side, only high voltage side or low voltage side of transformers in distribution systems. Criterions evaluated for each scheme are active and reactive power losses in whole system, voltage value at all buses, installation and operation cost and accumulative profit saving. Standard with and without transformer branches in distribution systems and Newton-Raphson method are introduced to make clear about the way to analyze power flows in whole system. Optimal placements and sizes for capacitor banks are determined by using a proposed algorithm and optimal capacitor placement tool in ETAP software. Simulation results can help to show the comparisons, evaluations and make decision about optimal capacitor placements and sizes. The contribution shows the best scheme that install capacitors at low voltage side of transformers because it has the lowest implemented capacity, highest economic factors while voltage quality is always in allowable range. Achieved results can be applied in any distribution system, help managers have overall review and decide optimal placements and sizes for capacitor banks. Keywords: Capacitor bank, OCP Tool, ETAP software, Optimal placement, Optimal size, Voltage quality, Optimal cost.","PeriodicalId":13809,"journal":{"name":"International Journal of Current Research and Review","volume":"17 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135872987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The purpose of this research is to analyze effect of dropshipper service, availability, and customer loyalty on customer satisfaction in the Robyshop Online Store. This type of research is quantitative research. Population in this research is consumers of the Robyshop Online Store. Sampling method used in this research is Malhotra sampling. The data collection techniques used are interview, questionnaire, observation, and literature study. The data analysis used in this research is multiple linear regression analysis. The research results show that dropshipper service, availability, and customer loyalty simultaneously have a significant effect on customer satisfaction in the Robyshop Online Store. Dropshipper service has a positive and significant effect on customer satisfaction in the Robyshop Online Store. Availability has a positive and significant effect on customer satisfaction in the Robyshop Online Store. Customer loyalty has a positive and significant effect on customer satisfaction in the Robyshop Online Store. Keywords: Dropshipper Service, Availability, Customer Loyalty, Customer Satisfaction
{"title":"Effect of Dropshipper Service, Availability, and Customer Loyalty on Customer Satisfaction in the Robyshop Online Store","authors":"Mochamad Fakhri Akbar, Akhmad Tajudin, Ufi Rumefi","doi":"10.52403/ijrr.20231063","DOIUrl":"https://doi.org/10.52403/ijrr.20231063","url":null,"abstract":"The purpose of this research is to analyze effect of dropshipper service, availability, and customer loyalty on customer satisfaction in the Robyshop Online Store. This type of research is quantitative research. Population in this research is consumers of the Robyshop Online Store. Sampling method used in this research is Malhotra sampling. The data collection techniques used are interview, questionnaire, observation, and literature study. The data analysis used in this research is multiple linear regression analysis. The research results show that dropshipper service, availability, and customer loyalty simultaneously have a significant effect on customer satisfaction in the Robyshop Online Store. Dropshipper service has a positive and significant effect on customer satisfaction in the Robyshop Online Store. Availability has a positive and significant effect on customer satisfaction in the Robyshop Online Store. Customer loyalty has a positive and significant effect on customer satisfaction in the Robyshop Online Store. Keywords: Dropshipper Service, Availability, Customer Loyalty, Customer Satisfaction","PeriodicalId":13809,"journal":{"name":"International Journal of Current Research and Review","volume":"190 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135371819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This research aims to test and analyze the effect of the Islamicity performance index, capital adequacy ratio, and corporate social responsibility on profitability with intellectual capital as a moderating variable in Sharia Public Banks listed on the Financial Services Authority period of 2016-2021. This associative-quantitative research employs secondary data. The research population is made up of 12 companies, and the sample are taken using a purposive sampling method, totalling 8 companies with criteria: Sharia banks that presented their financial statements from 2016-2021 period on the Financial Services Authority. Data obtained are analyzed using panel data regression method. This research results indicate that the profit-sharing ratio had an insignificant and negative effect, zakat performance ratio has a significant and positive effect, the Islamic income ratio has an insignificant and negative effect, the capital adequacy ratio has an insignificant positive effect, corporate social responsibility has an insignificant and positive effect on return on assets respectively. In addition, intellectual capital can moderate the effects of the profit-sharing ratio on return on assets, while intellectual capital does not moderate the effects of zakat performance ratio, Islamic income ratio, capital adequacy ratio, and corporate social responsibility on return on assets. Keywords: Islamicity Performance Index, Capital Adequacy Ratio, Corporate Social Responsibility, Intellectual Capital, Profitability.
{"title":"Analysis of Islamicity Performance Index, Capital Adequacy Ratio, and Corporate Social Responsibility on Profitability with Intellectual Capital as a Moderating Variable in Sharia Public Banks Listed on the Financial Services Authority Period of 2016-2021","authors":"Abdur Rahman Hakim, Khaira Amalia Fachrudin, Idhar Yahya","doi":"10.52403/ijrr.20231065","DOIUrl":"https://doi.org/10.52403/ijrr.20231065","url":null,"abstract":"This research aims to test and analyze the effect of the Islamicity performance index, capital adequacy ratio, and corporate social responsibility on profitability with intellectual capital as a moderating variable in Sharia Public Banks listed on the Financial Services Authority period of 2016-2021. This associative-quantitative research employs secondary data. The research population is made up of 12 companies, and the sample are taken using a purposive sampling method, totalling 8 companies with criteria: Sharia banks that presented their financial statements from 2016-2021 period on the Financial Services Authority. Data obtained are analyzed using panel data regression method. This research results indicate that the profit-sharing ratio had an insignificant and negative effect, zakat performance ratio has a significant and positive effect, the Islamic income ratio has an insignificant and negative effect, the capital adequacy ratio has an insignificant positive effect, corporate social responsibility has an insignificant and positive effect on return on assets respectively. In addition, intellectual capital can moderate the effects of the profit-sharing ratio on return on assets, while intellectual capital does not moderate the effects of zakat performance ratio, Islamic income ratio, capital adequacy ratio, and corporate social responsibility on return on assets. Keywords: Islamicity Performance Index, Capital Adequacy Ratio, Corporate Social Responsibility, Intellectual Capital, Profitability.","PeriodicalId":13809,"journal":{"name":"International Journal of Current Research and Review","volume":"205 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135372202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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