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International Conference on Nanoscience, Engineering and Technology (ICONSET 2011)最新文献

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Magneto-optical isolation and topological edge states at singular points in plasmonic structures 磁光隔离和等离子体结构奇异点的拓扑边缘态
G. Veronis, Yin Huang, Yuecheng Shen, Vahid Foroughi Nezhad, Chenglong You
We introduce a nanoplasmonic isolator consisting of a cavity coupled to a metal-dielectric-metal (MDM) waveguide. The waveguide and cavity are filled with a magneto-optical (MO) material, and the structure is under a static magnetic field. We show that, when MO activity is present, the cavity becomes a traveling wave resonator with unequal decay rates into the forward and backward directions. As a result, the structure operates as an isolator. We also introduce non-Hermitian plasmonic waveguide-cavity systems with topological edge states (TESs) at singular points. The structure unit cells consist of an MDM waveguide side-coupled to MDM stub resonators with modulated distances between adjacent stubs. In such structures the modulated distances introduce an effective gauge magnetic field. We show that such structures achieve extremely high sensitivity of the reflected light intensity. TESs at singular points could lead to singularity-based plasmonic devices with enhanced performance.
我们介绍了一种纳米等离子体隔离器,由一个腔耦合到一个金属-介电-金属(MDM)波导组成。波导和腔体由磁光材料填充,结构处于静态磁场下。我们发现,当MO活动存在时,腔变成了一个行波谐振器,在正向和反向方向上具有不等的衰减速率。因此,该结构起着隔离作用。我们还介绍了具有奇异点拓扑边缘态(TESs)的非厄米等离子体波导腔系统。该结构单元由MDM波导侧耦合到MDM短根谐振器组成,相邻短根之间具有调制距离。在这种结构中,调制的距离引入了有效的规范磁场。我们证明了这种结构对反射光强度具有极高的灵敏度。奇点处的TESs可以导致性能增强的基于奇点的等离子体器件。
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引用次数: 0
Classification between early onset Alzheimer's disease and frontotemporal dementia using a single neuroimaging feature 使用单一神经影像学特征对早发性阿尔茨海默病和额颞叶痴呆进行分类
Agnès Pérez-Millan, Laia Borrell, José Contador, M. Balasa, A. Lladó, R. Sánchez-Valle, R. Sala‐Llonch
INTRODUCTION: Early Onset Alzheimer’s Disease (EOAD, <65 years) and Frontotemporal Dementia (FTD) are common forms of early-onset dementia. Therefore, there is a need to establish accurate diagnosis and to obtain markers for disease tracking. We combined supervised and unsupervised machine learning (ML) to discriminate between EOAD and FTD patients. METHODS: We included 3T-T1 MRI of 203 subjects under 65 years old: 66 healthy controls (CTR, age: 55.0 ± 8.4 years), 85 EOAD patients (age: 57.3 ± 6.1 years) and 52 FTD patients (age: 57.9 ± 4.8 years). We obtained subcortical gray matter volumes and cortical thickness (CTh) regional measures using FreeSurfer. For ML, we performed a Principal Component Analysis (PCA) of all volumes and CTh values. Then, the first principal component (PC) was introduced into a Support Vector Machine (SVM). Overall performance was assessed using k-fold cross-validation. RESULTS: Our algorithm had an accuracy of 87.2 ± 14.2 % in the CTR vs EOAD classification, 80.8 ± 20.4% for CTR vs FTD, 66.5 ± 12.9 % for EOAD vs FTD and 65.2 ± 10.6% when discriminating the three groups. We used the weights of the first PC to create disease-specific patterns. CONCLUSION: By using a single feature that combines information from CTh and subcortical volumes, our algorithm classifies CTR, EOAD and FTD with good accuracy. We suggest that this approach can be used as a feature reduction strategy in ML algorithms while providing interpretable atrophy patterns.
简介:早发性阿尔茨海默病(EOAD, <65岁)和额颞叶痴呆(FTD)是早发性痴呆的常见形式。因此,有必要建立准确的诊断并获得疾病跟踪的标记物。我们结合监督和非监督机器学习(ML)来区分EOAD和FTD患者。方法:对203例65岁以下患者进行3T-T1 MRI检查,其中健康对照66例(CTR,年龄55.0±8.4岁),EOAD患者85例(年龄57.3±6.1岁),FTD患者52例(年龄57.9±4.8岁)。我们使用FreeSurfer获得皮层下灰质体积和皮层厚度(CTh)区域测量。对于ML,我们对所有体积和CTh值进行了主成分分析(PCA)。然后,将第一主成分(PC)引入支持向量机(SVM)。使用k-fold交叉验证评估总体性能。结果:该算法对CTR与EOAD的分类准确率为87.2±14.2%,对CTR与FTD的分类准确率为80.8±20.4%,对EOAD与FTD的分类准确率为66.5±12.9%,对三组的分类准确率为65.2±10.6%。我们使用第一台PC的重量来创建特定疾病的模式。结论:该算法利用CTh和皮层下体积信息相结合的单一特征,对CTR、EOAD和FTD进行了较好的分类。我们建议这种方法可以用作ML算法中的特征约简策略,同时提供可解释的萎缩模式。
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引用次数: 0
A method for modifying the surface properties of ZnO nanowires deposited as thin films on various substrates 一种改变ZnO纳米线在不同基底上薄膜表面特性的方法
V. Kolbjonoks, Vladimirs Kostjukevičs
In this paper, we demonstrate the approach of obtaining an array of ZnO nanowires, deposited as a thin film on different substrates (glass, Si plate, foil, etc.). As-obtained ZnO thin films have a hydrophilic state with water droplets with a contact angle value of 0°. Treatment of ZnO thin films with H2 gas (under specific conditions) changes the state of ZnO thin films to a hydrophobic state with a roll-off angle with the droplet of water 60°. However, ZnO thin films treatment with O2 gas makes ZnO thin films go back to a hydrophilic state. This operation can be repeated in a cycle manner using H2 and O2 gases to approach different states of ZnO thin films such as hydrophilic and hydrophobic. Thin films of ZnO nanowires can be deposited on a variety of substrates such as glasses, metals, and polyamides.
在本文中,我们展示了获得ZnO纳米线阵列的方法,该阵列作为薄膜沉积在不同的衬底(玻璃,硅板,箔等)上。所得ZnO薄膜具有亲水性,水滴接触角为0°。用H2气体处理ZnO薄膜(在特定条件下)使ZnO薄膜变为疏水状态,且与液滴的滚脱角为60°。然而,用O2气体处理ZnO薄膜,使ZnO薄膜回到亲水性状态。该操作可以循环重复,使用H2和O2气体来接近ZnO薄膜的不同状态,如亲水性和疏水性。ZnO纳米线薄膜可以沉积在各种衬底上,如玻璃、金属和聚酰胺。
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引用次数: 0
Development of a fiber-based microfluidic flow cytometry platform using viscoelastic fluids for polydisperse particle suspensions 纤维微流控流式细胞仪平台的开发,粘弹性流体用于多分散颗粒悬浮液
M. Serhatlioglu, Emil Alstrup Jensen, M. Niora, A. T. Hansen, Christian Friberg Nielsen, Michelle Maria Theresia Jansman, L. Hosta‐Rigau, M. Dziegiel, K. Berg-Sørensen, I. Hickson, A. Kristensen
Flow cytometry (FC) is a pivotal tool for studying the physical and chemical properties of particles. State-of-the-art FC systems are highly advanced, yet they are expensive, bulky, and require high sample volume, qualified operators, and periodic maintenance. The manipulation of particles suspended in viscoelastic fluids has received increasing attention, especially for miniaturized flow cytometry technologies. This study presents a miniaturized optical capillary FC device using the viscoelastic focusing technique. A straight, one inlet/outlet microcapillary device is precisely aligned to a fiber-coupled laser source and detectors. Forward scattered, side scattered, and fluorescently emitted light signals are collected and analyzed in a real-time environment. The developed platform fits onto an inverted microscope stage enabling real-time microscopy imaging of the particles of interest together with the flow cytometry analysis. We achieved stable viscoelastic focusing and performed FC measurements for rigid polystyrene beads (diameters: 2 – 15 μm), non-spherical human erythrocytes, and canonical shape metaphase human chromosomes. We performed cytometry measurements with a throughput of 100 events/s yielding a coefficient of variation of 2%. This newly developed FC device is a versatile tool and can be operated with any inverted microscope to get the mutual benefits of optical and imaging FC measurements. Furthermore, it is possible to extend these benefits by adding more back-end tools, such as optical trapping and Raman spectroscopy.
流式细胞仪(FC)是研究颗粒物理化学性质的关键工具。最先进的FC系统非常先进,但它们价格昂贵,体积庞大,需要高样本量,合格的操作人员和定期维护。悬浮在粘弹性流体中的颗粒的操作已受到越来越多的关注,特别是小型化的流式细胞术技术。本文研究了一种采用粘弹性聚焦技术的小型光学毛细管FC装置。直,一个入口/出口微毛细管装置是精确对准光纤耦合激光源和探测器。在实时环境中收集和分析前向散射、侧向散射和荧光发射的光信号。开发的平台适合于倒置显微镜平台,可以对感兴趣的颗粒进行实时显微镜成像,并进行流式细胞术分析。我们实现了稳定的粘弹性聚焦,并对刚性聚苯乙烯珠(直径:2 - 15 μm)、非球形人红细胞和规范形中期人染色体进行了FC测量。我们以100个事件/秒的通量进行了细胞术测量,变异系数为2%。这个新开发的FC设备是一个多功能的工具,可以与任何倒置显微镜操作,以获得光学和成像FC测量的共同利益。此外,可以通过增加更多的后端工具(如光捕获和拉曼光谱)来扩展这些优势。
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引用次数: 0
High emissive contrast of patterned tungsten-doped VO2 thin film composites 图案化掺杂钨氧化钨薄膜复合材料的高发射对比度
G. Hunt, J. Miragliotta, L. Oh, J. Ginn, A. Warren, D. Shrekenhamer
Thermal regulation is essential for numerous applications across multiple industries such as the efficient temperature control of indoor facilities and the reliable operation of many electronic systems. Vanadium dioxide (VO2) is a phase change material that is well-suited for thermal regulation as a result of its ultrafast, reversible, solid-state transition at 68°C that produces a significant contrast in its infrared (IR) emissive properties. To meet application demands, VO2’s transition temperature can be tuned via doping with a reduction in temperature of ~22 °C per atomic percent tungsten (at. % W6+). However, historically this decrease in the transition temperature has coincided with a reduction in IR optical contrast between the two phases. In this investigation, we demonstrate that by patterning VO2 thin film composites with preoptimized thicknesses, a thermal regulation system with a tunable transition temperature and no significant degradation of contrast between the states is produced. Through carefully selected user-defined patterning of the undoped VO2 layer within the multilayer film, a 64% operating optical contrast was achieved across the 8 – 13 μm spectral region as compared to 42% in the as-deposited film. Additionally, at a doping level of 1.7%, the transition temperature in a VO2 thin film composite with micron-scaled patterning was reduced to 25°C while maintaining 58% emissive contrast in the 8 – 13 μm spectral region.
热调节对于多个行业的众多应用至关重要,例如室内设施的有效温度控制和许多电子系统的可靠运行。二氧化钒(VO2)是一种相变材料,非常适合热调节,因为它在68°C下具有超快,可逆的固态转变,其红外(IR)发射特性具有显着的对比。为了满足应用需求,VO2的转变温度可以通过掺杂来调整,每原子百分比钨(at)的温度降低~22°C。%将+)。然而,从历史上看,这种转变温度的降低与两相之间红外光学对比度的降低相一致。在这项研究中,我们证明了通过预先优化厚度的VO2薄膜复合材料的图像化,产生了一个具有可调转变温度且状态之间对比度没有明显退化的热调节系统。通过精心选择多层膜内未掺杂的VO2层的自定义图型,在8 - 13 μm光谱区域内实现了64%的工作光学对比度,而在沉积膜中为42%。此外,当掺杂量为1.7%时,具有微米尺度图案的VO2薄膜复合材料的转变温度降至25℃,同时在8 ~ 13 μm光谱区域保持58%的发射对比度。
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引用次数: 0
Waveguide-coupled plasmonic nanogap-integrated phase change metasurfaces 波导耦合等离子体纳米隙集成相变超表面
Ahmed H. Elfarash, A. Mandal, B. Gholipour
Silicon photonics has emerged as the dominant technology platform for short distance, inter-chip communication for a variety of photonic computing and sensing applications due to its efficiency in modulation and confinement of light across telecom frequencies in addition to its inherent CMOS compatibility. The integration of metallic nanogaps within silicon photonic architectures provides a promising route for scaling this platform through the extreme confinement offered by plasmonics while providing an efficient route to interfacing future photonic integrated circuits with electronics. However, fabricating the gap sizes (< λg/10) required of plasmonic resonating nanogaps for efficient operation across telecommunication frequencies is highly challenging. Efficient coupling from waveguides to plasmonic nanogaps also remains a major source of loss. Here, we show that the key to merging these platforms lies in applying metamaterial/metasurface engineering principles to the design of the nanogap. Over the last decade, metamaterials and metasurfaces have emerged as a versatile toolkit for control and enhancement of light-matter interaction at application-driven wavelengths of interest in nanophotonic device platforms. We show that integrating a metagrating within a waveguide-coupled plasmonic nanogap made from Au, can enhance coupling to and from the silicon waveguides. Furthermore, the incorporation of the metasurface within the gap allows resonant response to be maintained at user-specified wavelength of interest with gaps as large as λg/5, drastically easing fabrication. Finally, we show that by incorporating a reconfigurable phase change chalcogenide alloy into the gap, non-volatile signal switching with modulation contrasts of up to 10:1 can be achieved across telecom frequencies.
硅光子学已经成为短距离、芯片间通信的主要技术平台,用于各种光子计算和传感应用,因为它在调制和限制跨电信频率的光方面具有效率,此外还有其固有的CMOS兼容性。在硅光子体系结构中集成金属纳米隙为通过等离子体提供的极端限制来扩展该平台提供了一条有前途的途径,同时为未来的光子集成电路与电子设备的接口提供了一条有效的途径。然而,为了在电信频率上有效运行,制造等离子共振纳米隙所需的间隙尺寸(< λg/10)是极具挑战性的。从波导到等离子体纳米隙的有效耦合也是损耗的主要来源。在这里,我们展示了融合这些平台的关键在于将超材料/超表面工程原理应用于纳米间隙的设计。在过去的十年中,超材料和超表面已经成为控制和增强纳米光子器件平台中应用驱动波长的光-物质相互作用的多功能工具包。我们的研究表明,在由金制成的波导耦合等离子体纳米隙内集成一个介栅,可以增强与硅波导之间的耦合。此外,在间隙内结合超表面允许共振响应保持在用户指定的感兴趣波长,间隙大至λg/5,大大简化了制造。最后,我们表明,通过在间隙中加入可重构的相变硫系合金,可以在电信频率上实现调制对比度高达10:1的非易失性信号切换。
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引用次数: 1
Direct detection of cell membrane slope fluctuations upon adding Latrunculin B using optical tweezers and single probe particle 使用光镊和单探针颗粒直接检测加入拉曲库林B后细胞膜斜率波动
S. Roy, Snigdhadev Chakraborty, Lokesh Muruga, Rahul Vaippuly, Vandana Yadav, S. Bajpai, Privitha Edwina, Basudev Roy
The cell membrane has fluctuations due to thermal and athermal sources. That causes the membrane to flicker. Conventionally, only the normal (perpendicular to the membrane) fluctuations are studied and then used to ascertain the membrane properties like the bending rigidity. It is here that we introduce a different concept, namely the slope fluctuations of the cell membrane which can be modelled as a gradient of the normal fluctuations. This can be studied using a new technique where a birefringent particle placed on the membrane turns in the out of plane sense, called the pitch sense. We introduce the pitch detection technique in optical tweezers relying upon asymmetric scattering from a birefringent particle under crossed polarizers. We then go on to use this pitch detection technique to ascertain the power spectral density of membrane slope fluctuations and find it to be (frequency)−1 while the normal fluctuations yields (frequency)−5/3. We also explore a different regime where the cell is applied with the drug Latrunculin-B which inhibits actin polymerization and find the effect on membrane fluctuations. We find that even as the normal fluctuations now become (frequency)−4/3, the slope fluctuations spectrum still remains (frequency)−1, with exactly the same coefficient as the case when the drug was not applied. Thus, this presents a convenient opportunity to study the membrane parameters like bending rigidity as a function of time after applying the drug. This would be the first time the membrane bending rigidity could be studied as a function of time upon the application of Lat-B without reverting to AFM.
细胞膜由于热源和非热源而有波动。这就导致细胞膜闪烁。通常,只研究法向(垂直于膜)波动,然后用于确定膜的弯曲刚度等特性。在这里,我们引入了一个不同的概念,即细胞膜的斜率波动,它可以被建模为正常波动的梯度。这可以用一种新的技术来研究,在这种技术中,放置在膜上的双折射粒子以平面外的方式转动,称为音高感。介绍了一种基于双折射粒子在交叉偏振镜下的不对称散射的光镊基音检测技术。然后,我们继续使用这种基音检测技术来确定膜斜率波动的功率谱密度,并发现它是(频率)−1,而正常波动产生(频率)−5/3。我们还探索了一种不同的方法,在这种方法中,细胞应用了抑制肌动蛋白聚合的药物Latrunculin-B,并发现了对膜波动的影响。我们发现,即使正常波动现在变成(频率)−4/3,斜率波动谱仍然保持(频率)−1,其系数与未施用药物的情况完全相同。因此,这提供了一个方便的机会来研究膜参数,如抗弯刚度作为时间的函数后,应用药物。这将是第一次可以在不使用AFM的情况下,研究应用latb后膜的弯曲刚度作为时间的函数。
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引用次数: 0
New phase change materials for active photonics 新型有源光子学相变材料
Cosmin Constantin-Popescu, M. Shalaginov, F. Yang, Hung-I Lin, S. An, Christopher M. Roberts, P. Miller, M. Kang, K. Richardson, Hualiang Zhang, C. Rivero‐Baleine, Hyun Jung Kim, T. Gu, S. Vitale, Juejun Hu
Phase change materials or PCMs are truly remarkable compounds whose unique switchable properties have fueled an explosion of emerging applications in electronics and photonics. Nonetheless, if we discount their use in optical discs, PCMs’ immense application potential in photonics beyond data recording has only begun to unfold in the past decade. While the material requirements for optical or electronic data storage have been succinctly summarized as five key elements “writability, archival storage, erasability, readability, and cyclability” decades ago, these requirements are not universally relevant to the diverse set of photonic applications now being explored. It also comes as no surprise that existing PCMs, which have been heavily vetted for data storage, are not necessarily the optimal compositions for different use cases in optics and photonics. PCMs with their attributes custom-tailored for specific applications are therefore in demand as phase-change photonics continue to expand. Here we discuss the PCM selection and design strategies specifically for photonic applications as well as our recent work developing active integrated photonic devices and meta-surface optics based on new PCMs tailored for photonics.
相变材料(pcm)是一种真正了不起的化合物,其独特的可切换特性推动了电子和光子学领域新兴应用的爆炸式增长。尽管如此,如果我们不考虑它们在光盘中的应用,pcm在光子学领域的巨大应用潜力在过去的十年中才刚刚开始展现。虽然光学或电子数据存储的材料要求在几十年前被简洁地概括为五个关键要素“可写性、存档存储性、可擦除性、可读性和可循环性”,但这些要求与现在正在探索的各种光子应用并不普遍相关。同样不足为奇的是,现有的pcm已经经过了严格的数据存储审查,并不一定是光学和光子学中不同用例的最佳组合。因此,随着相变光子学的不断发展,具有为特定应用定制属性的pcm受到了需求。在这里,我们讨论了专门针对光子应用的PCM选择和设计策略,以及我们最近开发的有源集成光子器件和基于为光子学量身定制的新型PCM的元表面光学。
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引用次数: 1
Charge-density-wave phase transitions in quasi-2D 1T-TaS2/h-BN heterostructure devices 准二维1T-TaS2/h-BN异质结构器件中的电荷密度波相变
Jonas O. Brown, M. Taheri, Nick R. Sesing, T. Salguero, F. Kargar, A. Balandin
In this invited contribution, we review recent results and report on the phase transitions and de-pinning of the charge-density waves in single-crystal 1T-TaS2 thin-film and 1T-TaS2 / h-BN heterostructure devices. It is known that 1T-TaS2 reveals charge-density-wave phases below and above room temperature. The de-pinning of the charge-density waves in the quasi-2D materials is different from that in “conventional” bulk charge-density-wave materials with quasi-1D motifs in the crystal structure. The de-pinning process in 1T-TaS2 is not accompanied by an observable abrupt increase in electric current – in contrast to de-pinning in the conventional charge-density-wave materials with the quasi-1D crystal structure. The obtained results contribute to the development of the charge-density-wave devices for applications in electronics and optoelectronics.
在这篇特约论文中,我们回顾了最近的研究结果,并报告了单晶1T-TaS2薄膜和1T-TaS2 / h-BN异质结构器件中电荷密度波的相变和去钉钉。已知1T-TaS2在室温以下和室温以上显示电荷密度波相。准二维材料中电荷密度波的脱钉与晶体结构中具有准一维基元的“常规”体电荷密度波材料中的脱钉不同。与具有准一维晶体结构的传统电荷密度波材料的去钉过程相比,1T-TaS2的去钉过程并不伴随着可观察到的电流突然增加。所得结果有助于电荷密度波器件在电子学和光电子学中的应用。
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引用次数: 0
Nonlinear effects in modeling thin-film graded-bandgap solar cells 薄膜梯度带隙太阳能电池模型中的非线性效应
Faiz Ahmad, B. Civiletti, A. Lakhtakia, P. Monk
We model the effect of concentrated sunlight on CIGS thin-film graded-bandgap solar cells using an optoelectronic numerical model. For this purpose it is necessary first to solve the time-harmonic Maxwell equations to compute the electric field in the device due to sunlight and so obtain the electron-hole-pair generation rate. The generation rate is then used as input to a drift-diffusion model governing the flow of electrons and holes in the semiconductor components that predicts the current generated. The optical submodel is linear; however, the electrical submodel is nonlinear. Because the Shockley-Read-Hall contribution to the electron-hole recombination rate increases almost linearly at high electron/hole densities, the efficiency of the solar cell can improve with sunlight concentration. This is illustrated via a numerical study.
本文利用光电数值模型模拟了集中太阳光对CIGS薄膜梯度带隙太阳能电池的影响。为此,首先需要求解时谐麦克斯韦方程,计算器件中由于阳光作用而产生的电场,从而得到电子-空穴对的产生率。然后将产生速率作为漂移扩散模型的输入,该模型控制半导体组件中的电子和空穴流动,从而预测产生的电流。光学子模型是线性的;然而,电子模型是非线性的。由于肖克利-里德-霍尔对电子-空穴复合率的贡献在高电子/空穴密度下几乎呈线性增加,因此太阳能电池的效率可以随着太阳光浓度的增加而提高。这是通过数值研究来说明的。
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引用次数: 0
期刊
International Conference on Nanoscience, Engineering and Technology (ICONSET 2011)
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