Background: Fine needle aspiration cytology (FNAC) breast is generally considered as a rapid, safe and reliable diagnostic tool to distinguish benign from malignant breast lesions. Masood's Scoring Index has been proposed to categorize the breast lesions so as to help in surgical management. Objectives : To find out the usefulness of Modified Masoods scoring Index (MMSI) in proliferative breast diseases. Materials and Methods: This is a prospective study, done over period of one year 2012 to 2013, which includes fifty cases of palpable breast lesions with cytological diagnosis, followed by histological confirmation on biopsy. MMSI was applied on corresponding FNAC aspirates. Breast lesions were categorized into four groups, non proliferative breast disease, proliferative breast disease (PBD) without atypia, PBD with atypia and carcinoma breast. Results: Out of total 50 cases, age group ranged from 17-64 years. Modification of Masoods scoring system by shifting of score 9 and 10 from category I to category II, was found to be easily reproducible scoring method of breast lesions as it has improved the diagnostic accuracy of PBD. Conclusion: FNAC of breast is highly sensitive and specific modality for distinguishing benign and malignant lesions but its role in diagnosing proliferative breast lesions is debatable. MMSI can be applied on FNAC aspirates in stepwise manner after cytomorphological assessment to improve diagnostic accuracy of PBD without atypia.
{"title":"Value of scoring system in classification of proliferative breast disease on fine needle aspiration cytology","authors":"Rajan Shah, A. Sinha, A. Pradhan, R. Agarwal","doi":"10.7439/IJBR.V8I9.4371","DOIUrl":"https://doi.org/10.7439/IJBR.V8I9.4371","url":null,"abstract":"Background: Fine needle aspiration cytology (FNAC) breast is generally considered as a rapid, safe and reliable diagnostic tool to distinguish benign from malignant breast lesions. Masood's Scoring Index has been proposed to categorize the breast lesions so as to help in surgical management. Objectives : To find out the usefulness of Modified Masoods scoring Index (MMSI) in proliferative breast diseases. Materials and Methods: This is a prospective study, done over period of one year 2012 to 2013, which includes fifty cases of palpable breast lesions with cytological diagnosis, followed by histological confirmation on biopsy. MMSI was applied on corresponding FNAC aspirates. Breast lesions were categorized into four groups, non proliferative breast disease, proliferative breast disease (PBD) without atypia, PBD with atypia and carcinoma breast. Results: Out of total 50 cases, age group ranged from 17-64 years. Modification of Masoods scoring system by shifting of score 9 and 10 from category I to category II, was found to be easily reproducible scoring method of breast lesions as it has improved the diagnostic accuracy of PBD. Conclusion: FNAC of breast is highly sensitive and specific modality for distinguishing benign and malignant lesions but its role in diagnosing proliferative breast lesions is debatable. MMSI can be applied on FNAC aspirates in stepwise manner after cytomorphological assessment to improve diagnostic accuracy of PBD without atypia.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"318 1","pages":"530-537"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77547473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Allergic contact dermatitis (ACD) is the classic presentation of delayed type hypersensitivity response to exogenous agents.(1) Rapid urbanization, westernization of lifestyles, poor quality of objects available and extremely relaxed vigilance on adherence to product safety guidelines make any developing country like India highly susceptible to allergic contact dermatitis (ACD).(2) ACD affects social, occupational and psychological performance of an individual and adds to the morbidity. It accounts for 20% of the occupational dermatoses encountered in clinical practice . (3) The best treatment for ACD is avoidance of further exposure to the initiating allergen. This makes the identification of the allergen important. Patch test remains the standard test for the diagnosis and identification of ACD . (4) This study was conducted to identify the various presentations of ACD and to correlate the patch test results with the clinically suspected allergen. An attempt was also be made to identify the most common allergen in the study population.
{"title":"Clinical correlation of patch testing in suspected Allergic Contact Dermatitis","authors":"Yoganand J. Phulari","doi":"10.7439/ijbr.v8i9.4391","DOIUrl":"https://doi.org/10.7439/ijbr.v8i9.4391","url":null,"abstract":"Allergic contact dermatitis (ACD) is the classic presentation of delayed type hypersensitivity response to exogenous agents.(1) Rapid urbanization, westernization of lifestyles, poor quality of objects available and extremely relaxed vigilance on adherence to product safety guidelines make any developing country like India highly susceptible to allergic contact dermatitis (ACD).(2) ACD affects social, occupational and psychological performance of an individual and adds to the morbidity. It accounts for 20% of the occupational dermatoses encountered in clinical practice . (3) The best treatment for ACD is avoidance of further exposure to the initiating allergen. This makes the identification of the allergen important. Patch test remains the standard test for the diagnosis and identification of ACD . (4) This study was conducted to identify the various presentations of ACD and to correlate the patch test results with the clinically suspected allergen. An attempt was also be made to identify the most common allergen in the study population.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"20 1","pages":"547-550"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82024828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To find out resistance pattern and production of ESBL among gram negative blood culture isolates.Methods: This study was carried out in Microbiology laboratory, BP Koirala Institute of Health Sciences, Dharan, Nepal from July 2011-June 2012. Altogether 150 gram negative bacteria isolated from cases of blood stream infections were evaluated. Isolation, identification of bacteria, determination of antimicrobial susceptibility pattern and detection of ESBL were done following standard protocol.Results: Resistance to commonly used antimicrobials were noted in varying frequencies. Most of the isolates were resistant to ampicillin (97%) and sensitive to imipenem (98%). Forty seven percent of isolates were ESBL producers and a substantial number of isolates were resistant to at least 3 routinely used drugs.Conclusion: The study concluded that high resistance was found among the blood culture isolates and ESBL production was seen in a significant number of isolates.
{"title":"Antimicrobial resistant gram negative isolates from blood stream infections: A report from BPKIHS","authors":"Abhilasha Sharma, N. Bhattarai, B. Khanal","doi":"10.7439/ijbr.v8i9.4366","DOIUrl":"https://doi.org/10.7439/ijbr.v8i9.4366","url":null,"abstract":"Objective: To find out resistance pattern and production of ESBL among gram negative blood culture isolates.Methods: This study was carried out in Microbiology laboratory, BP Koirala Institute of Health Sciences, Dharan, Nepal from July 2011-June 2012. Altogether 150 gram negative bacteria isolated from cases of blood stream infections were evaluated. Isolation, identification of bacteria, determination of antimicrobial susceptibility pattern and detection of ESBL were done following standard protocol.Results: Resistance to commonly used antimicrobials were noted in varying frequencies. Most of the isolates were resistant to ampicillin (97%) and sensitive to imipenem (98%). Forty seven percent of isolates were ESBL producers and a substantial number of isolates were resistant to at least 3 routinely used drugs.Conclusion: The study concluded that high resistance was found among the blood culture isolates and ESBL production was seen in a significant number of isolates.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"1 1","pages":"509-513"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88975852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Colorectal carcinoma is becoming a public health issue in black Africans. Its frequency is increasing among people in their active productive years of life. Aim: The aim of this study is to describe the clinic-pathologic characteristics of colorectal carcinoma among the Nigerian Igbos. Methodology: The surgical day book, histology request and report forms of confirmed cases of colorectal carcinoma submitted to the Department of Anatomic Pathology, FMC Owerri between January 1, 2011 and December 31, 2016 were carefully studied for the demographic, clinical and histopathologic characteristics. Results: A total of 84 colonic biopsies were analyzed. The average age was 52.514.9 years with a range of 26 to 91 years. The male to female ratio was 1.6:1. The peak age of incidence was in the 41-50 age groups. The average duration of symptoms was 10.5 months with a range of 1 to 60 months. The commonest mode of presentation was abdominal mass 24.13% (28cases), abdominal pain 21.55% (25cases), and rectal bleeding 15.52% (18cases), intestinal obstruction 10.34% (12cases), constipation 8.62% (10cases) and abdominal distension 6.03% (7cases). The commonest sites involved along the length of the colon was the rectum 33 (39.29%) followed by the caecum 26 (30.95%), sigmoid colon 10 (11.9%), ascending colon 7(8.33%), descending colon 5 (5.95%) and transverse colon 3 (3.6%). 92.86% was adenocarcinoma, 1.2% was carcinoid and Alveolar rhabdomyosarcoma respectively. The tumors were metastatic in 19.05% (16) of cases. The distal colon was involved in 54.76% (46) and the proximal colon in 45.24% (38).
{"title":"Colorectal adenocarcinoma in nigerian Igbos- A clinicopathologic analysis","authors":"G. NnadiI, O. EgejuruR, N. EkwunifeC","doi":"10.7439/IJBR.V8I9.4341","DOIUrl":"https://doi.org/10.7439/IJBR.V8I9.4341","url":null,"abstract":"Background: Colorectal carcinoma is becoming a public health issue in black Africans. Its frequency is increasing among people in their active productive years of life. Aim: The aim of this study is to describe the clinic-pathologic characteristics of colorectal carcinoma among the Nigerian Igbos. Methodology: The surgical day book, histology request and report forms of confirmed cases of colorectal carcinoma submitted to the Department of Anatomic Pathology, FMC Owerri between January 1, 2011 and December 31, 2016 were carefully studied for the demographic, clinical and histopathologic characteristics. Results: A total of 84 colonic biopsies were analyzed. The average age was 52.514.9 years with a range of 26 to 91 years. The male to female ratio was 1.6:1. The peak age of incidence was in the 41-50 age groups. The average duration of symptoms was 10.5 months with a range of 1 to 60 months. The commonest mode of presentation was abdominal mass 24.13% (28cases), abdominal pain 21.55% (25cases), and rectal bleeding 15.52% (18cases), intestinal obstruction 10.34% (12cases), constipation 8.62% (10cases) and abdominal distension 6.03% (7cases). The commonest sites involved along the length of the colon was the rectum 33 (39.29%) followed by the caecum 26 (30.95%), sigmoid colon 10 (11.9%), ascending colon 7(8.33%), descending colon 5 (5.95%) and transverse colon 3 (3.6%). 92.86% was adenocarcinoma, 1.2% was carcinoid and Alveolar rhabdomyosarcoma respectively. The tumors were metastatic in 19.05% (16) of cases. The distal colon was involved in 54.76% (46) and the proximal colon in 45.24% (38).","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"98 1","pages":"501-505"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85864922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Primary ovarian pregnancy is one of the rarest varieties of ectopic pregnancies and is usually seen in young highly fertile multiparous women using intra uterine devices. Primary ovarian pregnancy accounts for 0.153% of all ectopic gestations. Patients frequently present with lower abdominal pain and menstrual irregularities. Preoperative diagnosis is challenging in these patients. Awareness about primary ovarian ectopic pregnancy is very important as delay in the diagnosis of this condition may result in certain complications including rupture, operative problems and secondary implantation. Here, we are presenting three cases of primary ovarian ectopic pregnancies presented with acute abdominal pain and were diagnosed as a case of a ruptured ectopic pregnancy. All these cases were confirmed intra-operatively and histopathologically as primary ovarian pregnancy. All the cases were successfully managed by surgery.
{"title":"Primary ovarian ectopic pregnancy: A rare condition (Case Series)","authors":"N. Varun, R. Tanwar, S. Prasad, N. Gupta","doi":"10.7439/IJBR.V8I9.4357","DOIUrl":"https://doi.org/10.7439/IJBR.V8I9.4357","url":null,"abstract":"Primary ovarian pregnancy is one of the rarest varieties of ectopic pregnancies and is usually seen in young highly fertile multiparous women using intra uterine devices. Primary ovarian pregnancy accounts for 0.153% of all ectopic gestations. Patients frequently present with lower abdominal pain and menstrual irregularities. Preoperative diagnosis is challenging in these patients. Awareness about primary ovarian ectopic pregnancy is very important as delay in the diagnosis of this condition may result in certain complications including rupture, operative problems and secondary implantation. Here, we are presenting three cases of primary ovarian ectopic pregnancies presented with acute abdominal pain and were diagnosed as a case of a ruptured ectopic pregnancy. All these cases were confirmed intra-operatively and histopathologically as primary ovarian pregnancy. All the cases were successfully managed by surgery.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"121 1","pages":"551-553"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78173040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Shashirekha, R. R. Singh, H. Ravikiran, K. Prasad, P. Sreeramulu
Background: Most diseases of the breast present as a palpable mass. The majority of breast lesions are not malignant, and most benign lesions do not progress to cancer; however the accuracy of diagnosis can be increased by a combination of preoperative tests like physical examination, mammography, fine-needle aspiration cytology (FNAC), and Tru cut needle biopsy (TGNB) or core needle biopsy (CNB). FNAC has grown in popularity and became the first initial used procedure after history taking and clinical examination for diagnosis of solid and cystic breast lumps. This study was designated to investigate the accuracy of FNAC in comparison to TCNB for diagnosis of breast masses. Design: Retrospective Study Materials &Methods: In this study, 62 patients having breast lumps were studied during the period from January 2014 to January 2017 in terms of FNAC and Trucut Biopsy and were compared with tissue diagnosis. Variables like age, marital status, duration, size, menstrual status & site were analyzed using statistical analysis. Results: Out of 62 patients with breast lump, 32 were diagnosed with Benign Breast lesions, and 30 with malignant lesions. Sensitivity of FNAC and TRUCUT biopsy were 84.34% and 97.1% respectively. TRUCUT was more accurate when compared to FNAC.
{"title":"Fine needle aspiration cytology versus trucut biopsy in the diagnosis of breast cancer- A comparative study","authors":"C. Shashirekha, R. R. Singh, H. Ravikiran, K. Prasad, P. Sreeramulu","doi":"10.7439/IJBR.V8I9.4329","DOIUrl":"https://doi.org/10.7439/IJBR.V8I9.4329","url":null,"abstract":"Background: Most diseases of the breast present as a palpable mass. The majority of breast lesions are not malignant, and most benign lesions do not progress to cancer; however the accuracy of diagnosis can be increased by a combination of preoperative tests like physical examination, mammography, fine-needle aspiration cytology (FNAC), and Tru cut needle biopsy (TGNB) or core needle biopsy (CNB). FNAC has grown in popularity and became the first initial used procedure after history taking and clinical examination for diagnosis of solid and cystic breast lumps. This study was designated to investigate the accuracy of FNAC in comparison to TCNB for diagnosis of breast masses. Design: Retrospective Study Materials &Methods: In this study, 62 patients having breast lumps were studied during the period from January 2014 to January 2017 in terms of FNAC and Trucut Biopsy and were compared with tissue diagnosis. Variables like age, marital status, duration, size, menstrual status & site were analyzed using statistical analysis. Results: Out of 62 patients with breast lump, 32 were diagnosed with Benign Breast lesions, and 30 with malignant lesions. Sensitivity of FNAC and TRUCUT biopsy were 84.34% and 97.1% respectively. TRUCUT was more accurate when compared to FNAC.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"20 1","pages":"497-500"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73955916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Janani Suraksha Yojana (JSY) is 100% centrally sponsored scheme which integrates the benefit of cash assistance with institutional care during antenatal, delivery and immediate post partum care. It is very crucial to educate beneficiaries about certain maternity health benefit schemes like JSY to improve the health indicators of country. The study was conducted to assess the knowledge and attitudes of antenatal and postnatal mothers at tertiary care hospital in Pune City. A Cross-sectional study was conducted at Bharati Hospital, Pune where 65 antenatal and postnatal mothers at Obstetrics and Gynecology were included as a study participant. A structured questionnaire in local language was used and the information was collected by interview method. The data was entered into Microsoft Office Excel Sheet and was analyzed. Out of 65 participants, 45 (69.23%) were not aware about JSY and only 20 (30.76%) participants had knowledge about JSY. Of 20 participants, 15 (75%) had received JSY information from Television and Newspaper and 5 (25%) participants were informed by ASHAs. The present study revealed inadequacies in knowledge of antenatal and postnatal mothers regarding JSY. However positive attitudes were found in those mothers who were aware about this scheme.
{"title":"Knowledge and attitudes of antenatal and postnatal mothers towards Janani Suraksha Yojana at Tertiary Care Hospital, Pune","authors":"Neha Ande, R. Bogam, Salil Barsode","doi":"10.7439/IJBR.V8I9.4370","DOIUrl":"https://doi.org/10.7439/IJBR.V8I9.4370","url":null,"abstract":"Janani Suraksha Yojana (JSY) is 100% centrally sponsored scheme which integrates the benefit of cash assistance with institutional care during antenatal, delivery and immediate post partum care. It is very crucial to educate beneficiaries about certain maternity health benefit schemes like JSY to improve the health indicators of country. The study was conducted to assess the knowledge and attitudes of antenatal and postnatal mothers at tertiary care hospital in Pune City. A Cross-sectional study was conducted at Bharati Hospital, Pune where 65 antenatal and postnatal mothers at Obstetrics and Gynecology were included as a study participant. A structured questionnaire in local language was used and the information was collected by interview method. The data was entered into Microsoft Office Excel Sheet and was analyzed. Out of 65 participants, 45 (69.23%) were not aware about JSY and only 20 (30.76%) participants had knowledge about JSY. Of 20 participants, 15 (75%) had received JSY information from Television and Newspaper and 5 (25%) participants were informed by ASHAs. The present study revealed inadequacies in knowledge of antenatal and postnatal mothers regarding JSY. However positive attitudes were found in those mothers who were aware about this scheme.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"29 1","pages":"521-523"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88741984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Neonatal mortality rate in India is high and stagnant. Special Care Newborn Units (SCNUs) have been set up to provide quality level II newborn-care services in several district hospitals to meet this challenge. The units are located in some districts where the burden of neonatal deaths is high, and access to special newborn care is poor. A cross-sectional survey was conducted to assess the availability of human resources, equipment, and quality care. Descriptive statistics were used for analyzing the inputs (resources) and outcomes (morbidity and mortality). The rate of mortality among admitted neonates was taken as the key outcome variable to assess the performance of the units. Chi-square test was used for analyzing the trend of case-fatality rate over a period of first year of operationalization of SNCU as the base. The Average Neonatal Mortality Rate reduced from 1.29% before the start of SNCU in 2012 to 0.845% after 1 year of start of SNCU in Rajouri district during 2013-14 study periods. Proportional mortality due to sepsis and low birth weight (LBW) declined significantly over a period of one year (LBW <2.5 kg). The major reasons for admission and the major causes of deaths were birth asphyxia, sepsis, and LBW/prematurity. Repair and maintenance of equipment were a major concern. It is possible to set up and manage quality SCNUs and improve the survival of newborns with LBW and sepsis in developing countries, although several challenges relating to human resources, maintenance of equipment, and maintenance of asepsis remain.
{"title":"A study to evaluate the functioning of Special Care Newborn Unit (SNCU) established at a District Hospital","authors":"R. Sharma, R. Khan, Shahid W. Anjum","doi":"10.7439/ijbr.v8i9.4369","DOIUrl":"https://doi.org/10.7439/ijbr.v8i9.4369","url":null,"abstract":"The Neonatal mortality rate in India is high and stagnant. Special Care Newborn Units (SCNUs) have been set up to provide quality level II newborn-care services in several district hospitals to meet this challenge. The units are located in some districts where the burden of neonatal deaths is high, and access to special newborn care is poor. A cross-sectional survey was conducted to assess the availability of human resources, equipment, and quality care. Descriptive statistics were used for analyzing the inputs (resources) and outcomes (morbidity and mortality). The rate of mortality among admitted neonates was taken as the key outcome variable to assess the performance of the units. Chi-square test was used for analyzing the trend of case-fatality rate over a period of first year of operationalization of SNCU as the base. The Average Neonatal Mortality Rate reduced from 1.29% before the start of SNCU in 2012 to 0.845% after 1 year of start of SNCU in Rajouri district during 2013-14 study periods. Proportional mortality due to sepsis and low birth weight (LBW) declined significantly over a period of one year (LBW <2.5 kg). The major reasons for admission and the major causes of deaths were birth asphyxia, sepsis, and LBW/prematurity. Repair and maintenance of equipment were a major concern. It is possible to set up and manage quality SCNUs and improve the survival of newborns with LBW and sepsis in developing countries, although several challenges relating to human resources, maintenance of equipment, and maintenance of asepsis remain.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"64 1","pages":"514-520"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82699115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Eclampsia is still prevalent in India with high maternal mortality. Aim: To analyse the factors affecting maternal outcome in antepartum eclampsia in BRD Medical College, Gorakhpur. Method: The present observational prospective study was undertaken in the Department of Obstetrics and Gynecology, BRD Medical College, Gorakhpur from August 2015 to July 2016. Women who presented with antepartum eclampsia were included in the study. Data analysed included various maternal parameters and the outcome of pregnancy. Results: During the defined period, incidence of antepartum eclampsia was 8.9%. Maternal death occurred in 3.7% of patients. Maternal outcome was significantly affected by numbers of convulsions, convulsion delivery interval, raised systolic and diastolic blood pressures and degree of proteinuria. However, age, parity and religion were not found to have any effect on maternal outcome. Conclusion: Better antenatal care, early recognition of disease, timely referral, and early initiation of treatment and termination of pregnancy improves outcome of eclampsia patients. Management of eclamptic patient should be performed at tertiary care centres, where ICU facilities, NICU facilities and multidisciplinary units are available.
{"title":"Factors affecting maternal outcome in antepartum eclampsia in BRD Medical College, Gorakhpur","authors":"V. Aditya, A. Verma, A. Kumari, Reena Srivastav","doi":"10.7439/IJBR.V8I9.4403","DOIUrl":"https://doi.org/10.7439/IJBR.V8I9.4403","url":null,"abstract":"Background: Eclampsia is still prevalent in India with high maternal mortality. Aim: To analyse the factors affecting maternal outcome in antepartum eclampsia in BRD Medical College, Gorakhpur. Method: The present observational prospective study was undertaken in the Department of Obstetrics and Gynecology, BRD Medical College, Gorakhpur from August 2015 to July 2016. Women who presented with antepartum eclampsia were included in the study. Data analysed included various maternal parameters and the outcome of pregnancy. Results: During the defined period, incidence of antepartum eclampsia was 8.9%. Maternal death occurred in 3.7% of patients. Maternal outcome was significantly affected by numbers of convulsions, convulsion delivery interval, raised systolic and diastolic blood pressures and degree of proteinuria. However, age, parity and religion were not found to have any effect on maternal outcome. Conclusion: Better antenatal care, early recognition of disease, timely referral, and early initiation of treatment and termination of pregnancy improves outcome of eclampsia patients. Management of eclamptic patient should be performed at tertiary care centres, where ICU facilities, NICU facilities and multidisciplinary units are available.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"1 1","pages":"541-546"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82250773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims and Objectives: To study epidemiological characteristics and clinical profile with specific attention to non classical/atypical clinical presentation and deficiencies/lacunae in post exposure prophylactic management as per WHO guidelines in adult rabies patients. Method: In this observational study, 96 cases of adult human rabies admitted at IDH of parent institute in 5 years duration (1/11/2008 to 31/10/2013) were studied. Data were collected and analyzed statistically. Results: Majority (95.9 %) of victim’s belonged to lower and lower middle socioeconomic class predominantly males (76.05 %) in age group of 12- 50 years (70.8 %) with WHO category III exposure (72.92 %). Principal biting animals was dog (95.84%). Majority (44.79%) cases had incubation period between 31-90 days post-exposure. Hydrophobia is the main pathognomonic feature of human rabies was present in 88.54 % cases. Majority (91.7 %) of cases had not received any rabies vaccination. 8.3 % victims received anti-rabies vaccine, 7.3 % received PCECV and 1% received PDEV. 1% had completed the course of PCECV (5 doses as relevant) and another 4.2% had received the 3 doses PCECV, 2.1% cases received 2 doses of PCECV. One case (1%) received 1 dose of PDEV. Conclusion: Human rabies is a major health problem, equally affecting rural as well urban population. The epidemiological characteristics and clinical profile of the disease are not much different from other studies and have not changed much over the decades. Hence, there are need to educate the community and health workers about the importance of immediate and adequate post-exposure treatment, to start effective control program for dog and to make availability of TCV as well as RIG.
{"title":"A Study of Human Rabies in Adults Admitted At Infectious Diseases Hospital of Tertiary Care Centre","authors":"P. Shingade, M. Vyawahare, M. Abhaykumar","doi":"10.7439/IJBR.V8I9.4399","DOIUrl":"https://doi.org/10.7439/IJBR.V8I9.4399","url":null,"abstract":"Aims and Objectives: To study epidemiological characteristics and clinical profile with specific attention to non classical/atypical clinical presentation and deficiencies/lacunae in post exposure prophylactic management as per WHO guidelines in adult rabies patients. Method: In this observational study, 96 cases of adult human rabies admitted at IDH of parent institute in 5 years duration (1/11/2008 to 31/10/2013) were studied. Data were collected and analyzed statistically. Results: Majority (95.9 %) of victim’s belonged to lower and lower middle socioeconomic class predominantly males (76.05 %) in age group of 12- 50 years (70.8 %) with WHO category III exposure (72.92 %). Principal biting animals was dog (95.84%). Majority (44.79%) cases had incubation period between 31-90 days post-exposure. Hydrophobia is the main pathognomonic feature of human rabies was present in 88.54 % cases. Majority (91.7 %) of cases had not received any rabies vaccination. 8.3 % victims received anti-rabies vaccine, 7.3 % received PCECV and 1% received PDEV. 1% had completed the course of PCECV (5 doses as relevant) and another 4.2% had received the 3 doses PCECV, 2.1% cases received 2 doses of PCECV. One case (1%) received 1 dose of PDEV. Conclusion: Human rabies is a major health problem, equally affecting rural as well urban population. The epidemiological characteristics and clinical profile of the disease are not much different from other studies and have not changed much over the decades. Hence, there are need to educate the community and health workers about the importance of immediate and adequate post-exposure treatment, to start effective control program for dog and to make availability of TCV as well as RIG.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"7 1","pages":"524-529"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75869508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：