首页 > 最新文献

International journal of biomedical research最新文献

英文 中文
Mental health morbidity among medical students 医学生心理健康的发病率
Pub Date : 2017-10-31 DOI: 10.7439/IJBR.V8I10.4429
S. V. Chincholikar, S. Kulkarni
Background: Mental morbidity is a state of mental and emotional discomfort. It often cripples the ability of the person to cope with day-to-day living. The undergraduate medical training is a stressful period and medical students undergo tremendous stress during various stages of the MBBS course. Aims and Objective: To study mental health morbidity among undergraduate medical students using self reporting Questionnaire in a private medical college. Materials and Methods: A cross-sectional study carried out among 331 MBBS students (178 females and 153 males) in a private medical college. A validated Self-Reporting Questionnaire (SRQ-20) was used for finding the probable psychiatric morbidity. Results: The study population comprised of 331students and all of them returned the filled questionnaire of which 41 %were females and 59% males. The composition of the study population was (first-year MBBS students, 75; second year MBBS students, 111; third-year MBBS students, 145). There were total 35 students having SRQ score more than 10 meaning that mental health morbidity was 11% (10.57%) among MBBS students. Conclusion: Mental morbidity in medical students calls for early detection, intervention and support.
背景:精神病态是一种精神和情绪不适的状态。它经常削弱人们应付日常生活的能力。本科医学训练是一个充满压力的阶段,医学生在MBBS课程的各个阶段都承受着巨大的压力。目的与目的:采用自述问卷对某私立医学院本科医学生心理健康状况进行调查。材料与方法:对某私立医学院MBBS学生331名(女178名,男153名)进行横断面研究。采用一份有效的自我报告问卷(SRQ-20)来发现可能的精神疾病。结果:研究对象为331名学生,所有学生均填写了问卷,其中女性占41%,男性占59%。研究人群的组成为:MBBS一年级学生,75人;MBBS二年级学生111人;MBBS三年级学生145人)。SRQ得分在10分以上的学生共有35人,心理健康发病率为11%(10.57%)。结论:医学生的精神疾病需要及早发现、干预和支持。
{"title":"Mental health morbidity among medical students","authors":"S. V. Chincholikar, S. Kulkarni","doi":"10.7439/IJBR.V8I10.4429","DOIUrl":"https://doi.org/10.7439/IJBR.V8I10.4429","url":null,"abstract":"Background: Mental morbidity is a state of mental and emotional discomfort. It often cripples the ability of the person to cope with day-to-day living. The undergraduate medical training is a stressful period and medical students undergo tremendous stress during various stages of the MBBS course. Aims and Objective: To study mental health morbidity among undergraduate medical students using self reporting Questionnaire in a private medical college. Materials and Methods: A cross-sectional study carried out among 331 MBBS students (178 females and 153 males) in a private medical college. A validated Self-Reporting Questionnaire (SRQ-20) was used for finding the probable psychiatric morbidity. Results: The study population comprised of 331students and all of them returned the filled questionnaire of which 41 %were females and 59% males. The composition of the study population was (first-year MBBS students, 75; second year MBBS students, 111; third-year MBBS students, 145). There were total 35 students having SRQ score more than 10 meaning that mental health morbidity was 11% (10.57%) among MBBS students. Conclusion: Mental morbidity in medical students calls for early detection, intervention and support.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"212 1","pages":"580-582"},"PeriodicalIF":0.0,"publicationDate":"2017-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76165181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sectional Complete Denture in a Patient with Sub Mucous Fibrosis- A Clinical Report 局部全口义齿治疗黏膜下纤维化1例临床报告
Pub Date : 2017-10-30 DOI: 10.7439/IJBR.V8I10.4397
Ranjani Thillaigovindan, E. Arumugam, R. Rai, Sheela Kumari
Microstomia is the term used to describe a condition of reduction in the size of the oral aperture which can be either acquired or congenital. Patients with microstomia have restricted mouth opening which causes difficulty in inserting and removing the prosthesis as a whole. Prosthetic rehabilitation of such patients is a challenge. Steps in the fabrication of complete denture like impression making and denture processing are modified in sectional complete denture. This enables the patient to use them in sections without much difficulty. This clinical report describes prosthodontic management of a completely edentulous patient with microstomia developed due to oral sub mucous fibrosis. Sectional maxillary denture was fabricated using a sectional impression tray technique. With the use of post and tubes in the palatal region, the denture could be easily inserted and removed in two parts. Mandibular denture was fabricated by the conventional method.
小口症是用来描述口孔缩小的一种情况的术语,这种情况可以是后天的也可以是先天性的。小口患者的开口受限,导致假体整体插入和取出困难。这类患者的假肢康复是一项挑战。改进了全口义齿的印模制作和义齿加工等全口义齿的制作步骤。这使得病人在剖面图中使用它们没有太大的困难。本临床报告描述一例因口腔黏膜下纤维化导致小口畸形的全无牙患者的修复治疗。采用分型印模托盘技术制作分型上颌义齿。在腭区使用桩和管,可以方便地分两部分插入和取出义齿。采用常规方法制作下颌骨义齿。
{"title":"Sectional Complete Denture in a Patient with Sub Mucous Fibrosis- A Clinical Report","authors":"Ranjani Thillaigovindan, E. Arumugam, R. Rai, Sheela Kumari","doi":"10.7439/IJBR.V8I10.4397","DOIUrl":"https://doi.org/10.7439/IJBR.V8I10.4397","url":null,"abstract":"Microstomia is the term used to describe a condition of reduction in the size of the oral aperture which can be either acquired or congenital. Patients with microstomia have restricted mouth opening which causes difficulty in inserting and removing the prosthesis as a whole. Prosthetic rehabilitation of such patients is a challenge. Steps in the fabrication of complete denture like impression making and denture processing are modified in sectional complete denture. This enables the patient to use them in sections without much difficulty. This clinical report describes prosthodontic management of a completely edentulous patient with microstomia developed due to oral sub mucous fibrosis. Sectional maxillary denture was fabricated using a sectional impression tray technique. With the use of post and tubes in the palatal region, the denture could be easily inserted and removed in two parts. Mandibular denture was fabricated by the conventional method.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"80 1","pages":"590-594"},"PeriodicalIF":0.0,"publicationDate":"2017-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90789646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study of noise levels between two architectural designs in Intensive Care Unit 重症监护室两种建筑设计噪音水平的比较研究
Pub Date : 2017-10-30 DOI: 10.7439/IJBR.V8I10.4384
E. Pathrose, S. Saseedharan, S. Poojary, Anant D Patil
In an earlier study done by the first author and team, the average noise levels in a mixed medical-surgical intensive care unit (ICU) ranged from 41dB to 58dB. In this study we attempted to study the impact of partitions between patient beds (effectively single patient cubicles) on the noise levels in the ICU. As per results of our study, introduction of simple, cost effective, non-movable, permanent partitions (not curtains) between patient beds (or presence of cubicles) caused a significant reduction in noise levels. This reduction in noise levels was seen across 24 hours (average noise range from 38 to 52dB).
在第一作者和研究小组早些时候做的一项研究中,内科-外科混合重症监护病房(ICU)的平均噪音水平在41分贝到58分贝之间。在这项研究中,我们试图研究病人病床之间的分区(有效的单个病人隔间)对ICU噪音水平的影响。根据我们的研究结果,在病床(或小隔间)之间引入简单、经济、不可移动的永久隔板(不是窗帘),显著降低了噪音水平。这种噪音水平的降低在24小时内都可以看到(平均噪音范围从38分贝到52分贝)。
{"title":"Comparative study of noise levels between two architectural designs in Intensive Care Unit","authors":"E. Pathrose, S. Saseedharan, S. Poojary, Anant D Patil","doi":"10.7439/IJBR.V8I10.4384","DOIUrl":"https://doi.org/10.7439/IJBR.V8I10.4384","url":null,"abstract":"In an earlier study done by the first author and team, the average noise levels in a mixed medical-surgical intensive care unit (ICU) ranged from 41dB to 58dB. In this study we attempted to study the impact of partitions between patient beds (effectively single patient cubicles) on the noise levels in the ICU. As per results of our study, introduction of simple, cost effective, non-movable, permanent partitions (not curtains) between patient beds (or presence of cubicles) caused a significant reduction in noise levels. This reduction in noise levels was seen across 24 hours (average noise range from 38 to 52dB).","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"8 1","pages":"560-565"},"PeriodicalIF":0.0,"publicationDate":"2017-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73529092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraocular pressure monitoring during prone percutaneous nephrolithotomy, should we pay attention? 俯卧位经皮肾镜取石术中眼压监测应注意什么?
Pub Date : 2017-10-30 DOI: 10.7439/IJBR.V8I10.4424
E. Sharma, J. Ratkal
Aims & objectives: Transitory post-operative visual loss in one of our patients following Percutaneus Nephrolithotomy (PCNL), led us to do a review the available literature on Post Operative Visual Loss (POVL) and to study the intraocular pressure (IOP) changes during prone PCNL. Introduction: POVL is a devastating complication in the setting of a non-ophthalmic surgery and can lead to severe legal consequences for the operating surgeon. Raised IOP leading to Ischaemic Optic Nerve Atrophy (ION) is one of the purported factor for POVL. Method: We serially measured IOP with a hand-held tonometer in 40 of our patients undergoing PCNL in prone position, at five-time point settings-Baseline; 10 minutes after anaesthesia (Supine 1); 10 minutes after putting the patient in prone position (Prone 1); At the end of the procedure (Prone 2); Before reversal of anaesthesia (Supine 2). Data analysis was done by repeated measures ANOVA and paired t tests using NCSS software. Results: Out of 40 patients 34(85%) were Males and 6 females (15%); with mean age of 46 years. The duration during which the patient was prone varied was 108.85 24.12 minutes. Measured IOP changed significantly in different positions, being highest in Prone 2 position. The rise in IOP had a linear relationship with the duration during which the patient was prone, reducing after anaesthesia reversal in supine position. Conclusions: Observing the safety measures in PCNL can go a long way in avoiding POVL, especially in those patients with large & complex stones necessitating the patient to be in prone position for longer durations.
目的:我们回顾了一例经皮肾镜取石术(PCNL)患者术后短暂性视力丧失的相关文献,并对俯卧位PCNL术后眼压(IOP)的变化进行了研究。简介:在非眼科手术中,POVL是一种毁灭性的并发症,可能导致手术医生严重的法律后果。IOP升高导致的缺血性视神经萎缩(ION)是POVL的因素之一。方法:我们用手持式眼压计连续测量40例俯卧位PCNL患者的IOP,在5个时间点设置基线;麻醉后10分钟(仰卧位1);俯卧位(俯卧位1)后10分钟;手术结束时(俯卧2位);麻醉逆转前(Supine 2)。数据分析采用重复测量方差分析和配对t检验,采用NCSS软件。结果:40例患者中男性34例(85%),女性6例(15%);平均年龄46岁。俯卧变化时间为108.85 24.12 min。不同体位测量IOP变化显著,俯卧位2最高。IOP的升高与患者俯卧位的持续时间呈线性关系,在仰卧位麻醉逆转后降低。结论:观察PCNL患者的安全措施对避免POVL有很大的帮助,特别是对于那些结石大而复杂,需要长时间俯卧位的患者。
{"title":"Intraocular pressure monitoring during prone percutaneous nephrolithotomy, should we pay attention?","authors":"E. Sharma, J. Ratkal","doi":"10.7439/IJBR.V8I10.4424","DOIUrl":"https://doi.org/10.7439/IJBR.V8I10.4424","url":null,"abstract":"Aims & objectives: Transitory post-operative visual loss in one of our patients following Percutaneus Nephrolithotomy (PCNL), led us to do a review the available literature on Post Operative Visual Loss (POVL) and to study the intraocular pressure (IOP) changes during prone PCNL. Introduction: POVL is a devastating complication in the setting of a non-ophthalmic surgery and can lead to severe legal consequences for the operating surgeon. Raised IOP leading to Ischaemic Optic Nerve Atrophy (ION) is one of the purported factor for POVL. Method: We serially measured IOP with a hand-held tonometer in 40 of our patients undergoing PCNL in prone position, at five-time point settings-Baseline; 10 minutes after anaesthesia (Supine 1); 10 minutes after putting the patient in prone position (Prone 1); At the end of the procedure (Prone 2); Before reversal of anaesthesia (Supine 2). Data analysis was done by repeated measures ANOVA and paired t tests using NCSS software. Results: Out of 40 patients 34(85%) were Males and 6 females (15%); with mean age of 46 years. The duration during which the patient was prone varied was 108.85 24.12 minutes. Measured IOP changed significantly in different positions, being highest in Prone 2 position. The rise in IOP had a linear relationship with the duration during which the patient was prone, reducing after anaesthesia reversal in supine position. Conclusions: Observing the safety measures in PCNL can go a long way in avoiding POVL, especially in those patients with large & complex stones necessitating the patient to be in prone position for longer durations.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"44 5 1","pages":"572-575"},"PeriodicalIF":0.0,"publicationDate":"2017-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79329582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of pain tolerance in different age group in community dwelling normal healthy adults 社区居住正常健康成人不同年龄组疼痛耐受性比较
Pub Date : 2017-10-30 DOI: 10.7439/IJBR.V8I10.4374
Harshadeep Kothare, Garima Rathi, Sonam Madavi, Yasmeen Fatema
Introduction: Pain Tolerance is that greater level of stimulus at which the subject request stimulus cessation . Various factors responsible for variation in pain tolerance are-Method of experimental pain induction, age, gender, race, and exercise, Different levels of anxiety, depression, or previous painful experiences of each subject can alter the reports of pain. The common ways to induce experimental pain in pain tolerance and threshold assessment studies are pressure, thermal, electrical, laser, cold induced pain. We in present study have use pain induced by pressure. Note that pain in these experimental study designs refers to the somatosensory aspect of pain. Aim: To compare pain tolerance in different age group in community dwelling normal healthy adults. Method: 90 asymptomatic community dwelling normal healthy adults were tested. Pressure algometer was used to measure pain tolerance. Algometer was placed on dorsal surface of middle segment of distal phalanges of middle finger. Initial reading of algometer should be 0 lbs. Pressure should be progressively increased until maximum pain which subject can experienced is reached. Subject should be instructed to announce stop verbally at that point and experimenter immediately retracts the algometer. Three readings were taken best of three was selected. Conclusion: For experimental induced pain by pressure- In community dwelling normal healthy adults pain tolerance decreases with an increase in age with maximum tolerance in age group ranging from 15-24 (young adult) and minimum in 45-64(old adult) and is not affected by sex of adult
疼痛耐受性是受试者要求停止刺激的更高水平的刺激。导致疼痛耐受性变化的各种因素有:实验疼痛诱导的方法、年龄、性别、种族和运动、每个受试者的不同程度的焦虑、抑郁或以前的疼痛经历可以改变疼痛报告。在疼痛耐受性和阈值评估研究中,常用的诱导实验疼痛的方法有压力、热、电、激光、冷诱导疼痛。我们在本研究中使用了由压力引起的疼痛。请注意,这些实验研究设计中的疼痛是指疼痛的体感方面。目的:比较社区居住正常健康成人不同年龄组的疼痛耐受性。方法:对90例无症状社区居住正常健康成人进行检测。采用压力计测量疼痛耐受性。Algometer放置于中指远端指骨中段背侧。测高仪的初始读数应为0磅。压力应逐渐增加,直到达到受试者所能承受的最大疼痛。应指示受试者在该点口头宣布停止,实验者立即收回算法。三个读数中选出最好的。结论:在社区居住的正常健康成人中,实验性压力性疼痛耐受性随年龄的增加而降低,最大耐受性在15-24岁年龄组(青壮年),最小的在45-64岁年龄组(老年人),不受成人性别的影响
{"title":"Comparison of pain tolerance in different age group in community dwelling normal healthy adults","authors":"Harshadeep Kothare, Garima Rathi, Sonam Madavi, Yasmeen Fatema","doi":"10.7439/IJBR.V8I10.4374","DOIUrl":"https://doi.org/10.7439/IJBR.V8I10.4374","url":null,"abstract":"Introduction: Pain Tolerance is that greater level of stimulus at which the subject request stimulus cessation . Various factors responsible for variation in pain tolerance are-Method of experimental pain induction, age, gender, race, and exercise, Different levels of anxiety, depression, or previous painful experiences of each subject can alter the reports of pain. The common ways to induce experimental pain in pain tolerance and threshold assessment studies are pressure, thermal, electrical, laser, cold induced pain. We in present study have use pain induced by pressure. Note that pain in these experimental study designs refers to the somatosensory aspect of pain. Aim: To compare pain tolerance in different age group in community dwelling normal healthy adults. Method: 90 asymptomatic community dwelling normal healthy adults were tested. Pressure algometer was used to measure pain tolerance. Algometer was placed on dorsal surface of middle segment of distal phalanges of middle finger. Initial reading of algometer should be 0 lbs. Pressure should be progressively increased until maximum pain which subject can experienced is reached. Subject should be instructed to announce stop verbally at that point and experimenter immediately retracts the algometer. Three readings were taken best of three was selected. Conclusion: For experimental induced pain by pressure- In community dwelling normal healthy adults pain tolerance decreases with an increase in age with maximum tolerance in age group ranging from 15-24 (young adult) and minimum in 45-64(old adult) and is not affected by sex of adult","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"26 1","pages":"554-559"},"PeriodicalIF":0.0,"publicationDate":"2017-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75901306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hodgkins Lymphoma presenting as a recurrence of primary disease at osseous site: Review of the Literature 霍奇金淋巴瘤表现为骨性部位原发疾病的复发:文献综述
Pub Date : 2017-10-30 DOI: 10.7439/IJBR.V8I10.4365
Nidhi Verma, Preeti Singh, B. Sharma, N. Singh, M. Rathi, Sushruti Sharma
Hodgkins lymphoma at an osseous site is not a common presentation. Here we are reporting a case of recurrence of Hodgkins lymphoma at osseous site with review of literature.
骨性部位的霍奇金淋巴瘤并不常见。我们在此报告一例霍奇金淋巴瘤骨性部位复发并复习文献。
{"title":"Hodgkins Lymphoma presenting as a recurrence of primary disease at osseous site: Review of the Literature","authors":"Nidhi Verma, Preeti Singh, B. Sharma, N. Singh, M. Rathi, Sushruti Sharma","doi":"10.7439/IJBR.V8I10.4365","DOIUrl":"https://doi.org/10.7439/IJBR.V8I10.4365","url":null,"abstract":"Hodgkins lymphoma at an osseous site is not a common presentation. Here we are reporting a case of recurrence of Hodgkins lymphoma at osseous site with review of literature.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"84 1","pages":"583-585"},"PeriodicalIF":0.0,"publicationDate":"2017-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81454663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Serum Vitamin B12, Folic acid and Homocysteine levels in Stroke Patients. 脑卒中患者血清维生素B12、叶酸和同型半胱氨酸水平的评价。
Pub Date : 2017-10-30 DOI: 10.7439/IJBR.V8I10.4419
N. JyothiD, Anita R. Bijoor, G. Sarma
Homocysteine, vitamin B12 andfolate have been associated with Cerebrovascular Accidents. A number of cross-sectional, case controlled cohort studies have demonstrated an association between high homocysteine level and increased risk of cardiovascular and cerebrovascular diseases, and there are equal numbers of studies that show no increase in risk, and there is still a debate as to the strength and validity of the association. This study was done with the objective to estimate the serum levels of vitamin B 12, folic acid and homocysteine in normal healthy controls and patients with stroke and to compare and correlate the values between these two groups. A total of 30 patients with acute ischemic stroke and 30 apparently healthy individuals were included in the study and their serum levels of vitamin B12, folic acid and homocysteine were estimated and statistically analyzed. On analysis; it was found that median serum level of vitamin B12 and folic acid in stroke patients was significantly lower than the controls (p < 0.001) and median serum level of total homocysteine in stroke patients was significantly higher than the controls (p= 0.009). It was also noted that there was a significant negative correlation between homocysteine and folic acid in controls while there was no significant correlation between homocysteine and vitamin B12 in both the groups. In conclusion, these results show that low levels of serum vitamin B12, folic acid and high levels of serum homocysteine are significantly associated with acute ischemic stroke.
同型半胱氨酸、维生素B12和叶酸与脑血管意外有关。许多横断面、病例对照的队列研究表明,高同型半胱氨酸水平与心脑血管疾病风险增加之间存在关联,同样数量的研究表明,风险没有增加,关于这种关联的强度和有效性仍存在争议。本研究的目的是估计正常健康对照和中风患者血清中维生素b12、叶酸和同型半胱氨酸的水平,并比较这两组之间的值。本研究共纳入30例急性缺血性脑卒中患者和30例表面健康个体,对其血清维生素B12、叶酸和同型半胱氨酸水平进行测定和统计分析。在分析;结果发现,脑卒中患者血清维生素B12和叶酸水平中位数显著低于对照组(p < 0.001),总同型半胱氨酸水平中位数显著高于对照组(p= 0.009)。同样值得注意的是,在对照组中同型半胱氨酸和叶酸之间存在显著的负相关,而在两组中同型半胱氨酸和维生素B12之间没有显著的相关。总之,这些结果表明,低水平的血清维生素B12、叶酸和高水平的血清同型半胱氨酸与急性缺血性卒中显著相关。
{"title":"Evaluation of Serum Vitamin B12, Folic acid and Homocysteine levels in Stroke Patients.","authors":"N. JyothiD, Anita R. Bijoor, G. Sarma","doi":"10.7439/IJBR.V8I10.4419","DOIUrl":"https://doi.org/10.7439/IJBR.V8I10.4419","url":null,"abstract":"Homocysteine, vitamin B12 andfolate have been associated with Cerebrovascular Accidents. A number of cross-sectional, case controlled cohort studies have demonstrated an association between high homocysteine level and increased risk of cardiovascular and cerebrovascular diseases, and there are equal numbers of studies that show no increase in risk, and there is still a debate as to the strength and validity of the association. This study was done with the objective to estimate the serum levels of vitamin B 12, folic acid and homocysteine in normal healthy controls and patients with stroke and to compare and correlate the values between these two groups. A total of 30 patients with acute ischemic stroke and 30 apparently healthy individuals were included in the study and their serum levels of vitamin B12, folic acid and homocysteine were estimated and statistically analyzed. On analysis; it was found that median serum level of vitamin B12 and folic acid in stroke patients was significantly lower than the controls (p < 0.001) and median serum level of total homocysteine in stroke patients was significantly higher than the controls (p= 0.009). It was also noted that there was a significant negative correlation between homocysteine and folic acid in controls while there was no significant correlation between homocysteine and vitamin B12 in both the groups. In conclusion, these results show that low levels of serum vitamin B12, folic acid and high levels of serum homocysteine are significantly associated with acute ischemic stroke.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"151 1","pages":"566-571"},"PeriodicalIF":0.0,"publicationDate":"2017-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76245221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Vitiligo and its association with hypoacusis: A case control study 白癜风及其与听觉减退的关系:一项病例对照研究
Pub Date : 2017-10-30 DOI: 10.7439/ijbr.v8i10.4394
S. Patil, Vasundhara Singh, Shweta Agarwal
Vitiligo is a pigmentary disorder with absence of functional melanocytes in the affected area. Melanocytes originate from neural crest and migrate to rest of the body in a cephalo-caudal manner in the embryonic life. Apart from epidermis and hair bulb in skin, they are also present in leptomeninges, inner ear, retina and uveal tract. In the inner ear melanocytes are present in endolymphatic sac, hair cells, vestibular organ and striavascularis. Vitiligo is not just skin deep and is also responsible for subclinical hypoacusis in majority of patients. Patients suffering from vitiligo affecting the head and neck region at the time of origin are more prone to the auditory dysfunction. Leucotrichia is another association with asymptomatic sensori-neural hypoacusis. This is due to the loss of melanocytes which have a protective role in inner ear. TEOAE and Pure tone audiometry can be used effectively for screening patients and these patients should be informed regarding the noise exposure and ototoxic drugs.
白癜风是一种色素紊乱,在受影响的区域缺乏功能性黑色素细胞。黑素细胞起源于神经嵴,在胚胎期以头尾方式向身体其他部位迁移。除了皮肤的表皮和毛球外,它们还存在于脑膜、内耳、视网膜和葡萄膜束中。在内耳,黑素细胞存在于内淋巴囊、毛细胞、前庭器官和血管纹层。白癜风不仅是皮肤深层的,也是大多数患者亚临床听觉减退的原因。发病时累及头颈部的白癜风患者更容易出现听觉障碍。白毛症是另一种与无症状感觉神经性听觉减退有关的疾病。这是由于在内耳具有保护作用的黑色素细胞的损失。TEOAE和纯音听力学可以有效地用于筛查患者,这些患者应了解噪音暴露和耳毒性药物。
{"title":"Vitiligo and its association with hypoacusis: A case control study","authors":"S. Patil, Vasundhara Singh, Shweta Agarwal","doi":"10.7439/ijbr.v8i10.4394","DOIUrl":"https://doi.org/10.7439/ijbr.v8i10.4394","url":null,"abstract":"Vitiligo is a pigmentary disorder with absence of functional melanocytes in the affected area. Melanocytes originate from neural crest and migrate to rest of the body in a cephalo-caudal manner in the embryonic life. Apart from epidermis and hair bulb in skin, they are also present in leptomeninges, inner ear, retina and uveal tract. In the inner ear melanocytes are present in endolymphatic sac, hair cells, vestibular organ and striavascularis. Vitiligo is not just skin deep and is also responsible for subclinical hypoacusis in majority of patients. Patients suffering from vitiligo affecting the head and neck region at the time of origin are more prone to the auditory dysfunction. Leucotrichia is another association with asymptomatic sensori-neural hypoacusis. This is due to the loss of melanocytes which have a protective role in inner ear. TEOAE and Pure tone audiometry can be used effectively for screening patients and these patients should be informed regarding the noise exposure and ototoxic drugs.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"14 1","pages":"586-589"},"PeriodicalIF":0.0,"publicationDate":"2017-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78754163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antimicrobial activity ofTriclosancoated sutures in vitro 三氯生包被缝合线的体外抗菌活性研究
Pub Date : 2017-09-30 DOI: 10.7439/IJBR.V8I9.4359
P. Saban, R. Gopal.
Introduction: Surgical site infections (S.S.I.) are most often due to the organisms present as indigenous flora and are a common problem in most of the hospitals. One of the risk factor is the presence of foreign material which includes suture. The use of antimicrobial coated sutures with the sustained action can be a useful supplement to the aseptic technique. Materials and methods: Randomly selected strains of MRSA, MRSE, Enterococcus, E.coli, Klebsiella & Pseudomonas species isolated from clinical samples in our laboratory were tested against the Triclosan coated and non-coated sutures commercially available. Result: Zone of inhibition was found with Triclosan coated suture and no zone of inhibition found with non coated sutures. Conclusion- Usage of sutures coated with antimicrobial agents like Triclosan can reduce the rates of surgical site infection.
手术部位感染(ssi)最常见的原因是微生物作为本地菌群存在,是大多数医院的常见问题。其中一个危险因素是异物的存在,包括缝合线。具有持续作用的抗菌涂层缝合线的使用可作为无菌技术的有益补充。材料与方法:随机选取本实验室临床样品中分离的MRSA、MRSE、肠球菌、大肠杆菌、克雷伯氏菌和假单胞菌,对市售的三氯生包被缝合线和非包被缝合线进行检测。结果:三氯生包覆缝线有抑制带,非包覆缝线无抑制带。结论-缝合线涂覆三氯生等抗菌药物可降低手术部位的感染率。
{"title":"Antimicrobial activity ofTriclosancoated sutures in vitro","authors":"P. Saban, R. Gopal.","doi":"10.7439/IJBR.V8I9.4359","DOIUrl":"https://doi.org/10.7439/IJBR.V8I9.4359","url":null,"abstract":"Introduction: Surgical site infections (S.S.I.) are most often due to the organisms present as indigenous flora and are a common problem in most of the hospitals. One of the risk factor is the presence of foreign material which includes suture. The use of antimicrobial coated sutures with the sustained action can be a useful supplement to the aseptic technique. Materials and methods: Randomly selected strains of MRSA, MRSE, Enterococcus, E.coli, Klebsiella & Pseudomonas species isolated from clinical samples in our laboratory were tested against the Triclosan coated and non-coated sutures commercially available. Result: Zone of inhibition was found with Triclosan coated suture and no zone of inhibition found with non coated sutures. Conclusion- Usage of sutures coated with antimicrobial agents like Triclosan can reduce the rates of surgical site infection.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"51 1","pages":"506-508"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91269142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of intestinal parasitic infection/infestation in differently abled people of Dharan, Nepal. 尼泊尔达兰不同能力人群肠道寄生虫感染/侵扰的流行情况
Pub Date : 2017-09-30 DOI: 10.7439/IJBR.V8I9.4400
N. Poudyal, L. Shrestha, S. Gautam, D. Yadav, R. Baral, R. Gurung
Introduction: Intestinal parasitic infestations are one of the most common causes of morbidity and mortality, infecting millions of people world-wide. Due to the various disability, differently-abled people are unable to maintain proper sanitation, making them more prone to intestinal parasitic infection.Objective: The objective of this study is to know the various parasitic infections in differently abled persons of Dharan municipality.Materials and Methods: Stool specimen were collected from individuals attending health camp for differently-able in Dharan municipality and direct wet mount was prepared using normal saline (0.9%) and Lugol's iodine (0.5%). The wet mount was observed under microscope for parasites.Results: Among 112 individuals screened, intestinal parasitosis was seen in 32.1% of people. Giardia lamblia (17%) was the most common parasite followed by Entamoeba histolytica (9%) and Ascaris lumbricoides (7.3%). Co-infection was a common trend with 33.3% of positive samples being co-infected with multiple parasites.Conclusion: The study shows that although the differently-abled people are prone to parasitic infection, the prevalence is same as normal people. Giardia lamblia, Entamoeba histolytica and Ascaris lumbricoides are the common parasites they harbour.
肠道寄生虫感染是最常见的发病和死亡原因之一,全世界有数百万人受到感染。由于各种残疾,不同能力的人无法保持适当的卫生设施,使他们更容易受到肠道寄生虫感染。目的:了解达兰市不同能力人群的各种寄生虫感染情况。材料与方法:收集在达兰市参加不同类型健康营的个体的粪便标本,用生理盐水(0.9%)和卢戈尔碘(0.5%)制备直接湿坐便器。在显微镜下观察湿壁的寄生情况。结果:112例患者中,肠道寄生虫病检出率为32.1%。最常见的寄生虫是兰第鞭毛虫(17%),其次是溶组织内阿米巴(9%)和类蚓蛔虫(7.3%)。合并感染是常见趋势,33.3%的阳性样本同时感染多种寄生虫。结论:本研究表明,虽然残疾人群易发生寄生虫感染,但其患病率与正常人相当。蓝氏贾第虫、溶组织内阿米巴和类蚓蛔虫是它们常见的寄生虫。
{"title":"Prevalence of intestinal parasitic infection/infestation in differently abled people of Dharan, Nepal.","authors":"N. Poudyal, L. Shrestha, S. Gautam, D. Yadav, R. Baral, R. Gurung","doi":"10.7439/IJBR.V8I9.4400","DOIUrl":"https://doi.org/10.7439/IJBR.V8I9.4400","url":null,"abstract":"Introduction: Intestinal parasitic infestations are one of the most common causes of morbidity and mortality, infecting millions of people world-wide. Due to the various disability, differently-abled people are unable to maintain proper sanitation, making them more prone to intestinal parasitic infection.Objective: The objective of this study is to know the various parasitic infections in differently abled persons of Dharan municipality.Materials and Methods: Stool specimen were collected from individuals attending health camp for differently-able in Dharan municipality and direct wet mount was prepared using normal saline (0.9%) and Lugol's iodine (0.5%). The wet mount was observed under microscope for parasites.Results: Among 112 individuals screened, intestinal parasitosis was seen in 32.1% of people. Giardia lamblia (17%) was the most common parasite followed by Entamoeba histolytica (9%) and Ascaris lumbricoides (7.3%). Co-infection was a common trend with 33.3% of positive samples being co-infected with multiple parasites.Conclusion: The study shows that although the differently-abled people are prone to parasitic infection, the prevalence is same as normal people. Giardia lamblia, Entamoeba histolytica and Ascaris lumbricoides are the common parasites they harbour.","PeriodicalId":13909,"journal":{"name":"International journal of biomedical research","volume":"20 1","pages":"538-540"},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83504174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
期刊
International journal of biomedical research
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1