Coronary artery occlusion is one of the most common cardiovascular diseases. In severe cases, bypass surgery is employed as a treatment, wherein a vessel is used as a bypass graft to restore blood flow by connecting the graft to the area beyond the coronary artery blockage. However, since these vessels are prone to reocclusion over time, investigating the hemodynamics of bypass flow is essential. In this study, samples of the three most common grafts, namely the saphenous vein, mammary artery, and radial artery, were obtained. Biaxial tension tests were performed on them to extract their anisotropic hyperelastic properties, which were then used in fluid-structure interaction (FSI) simulations. The results of the biaxial tension tests indicated that the saphenous vein exhibited significant stiffness compared to the other two grafts. The simulations also showed better wall shear stress distribution and higher blood flow velocities within the mammary artery. The saphenous vein exhibited large stresses and displacements at critical attachment points in both the fluid and solid domains, which may, over time, cause damage to the graft attachment and disrupt graft performance. The time average wall shear stress (TAWSS) in the toe region of the attachment area was 7.21 Pa for the saphenous vein, 5.99 Pa for the radial artery, and 3.05 Pa for the mammary artery. Additionally, the maximum displacement in the saphenous vein was 0.416 mm, 0.323 mm in the mammary artery, and 0.157 mm in the radial artery. The results of this research have potential applications in clinical cardiovascular studies and contribute to the development of practical treatment approaches.
扫码关注我们
求助内容:
应助结果提醒方式:
