Pub Date : 2017-05-28DOI: 10.24327/IJRSR.2017.0805.0254
M. Sasikala, R. Sundaraganapathy
{"title":"Optimization of extraction method for ipomoea aquatica forssk. [indian river spinach] from its whole plant","authors":"M. Sasikala, R. Sundaraganapathy","doi":"10.24327/IJRSR.2017.0805.0254","DOIUrl":"https://doi.org/10.24327/IJRSR.2017.0805.0254","url":null,"abstract":"","PeriodicalId":14198,"journal":{"name":"International journal of recent scientific research","volume":"1 1","pages":"16967-16971"},"PeriodicalIF":0.0,"publicationDate":"2017-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78092043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-28DOI: 10.24327/IJRSR.2017.0805.0283
S. Ganta, S. S.K
Ectopic pregnancy continues to be an obstetric challenge despite the advancement of technology. Abdominal pregnancy is rare (1in 10,000 births) and extremely serious form of extra uterine pregnancy. It can pose a major diagnostic hurdle with many being diagnosed only intra-operatively. We report a case of a 26 year old nullipara who presented with 6 weeks of amenorrhea with abdominal pain since 5 hours and one episode of syncope. She was hemodynamically unstable, routine ultrasound revealed an empty uterus with free fluid in the abdomen. It was diagnosed as a ruptured ectopic pregnancy and taken up for an emergency laparotomy. She had a right broad ligament ectopic pregnancy which had ruptured. Both the tubes, ovaries and uterus was found intact. Excision of the ruptured ectopic mass on the right side of the broad ligament was done. The specimen was sent for histopathological examination and confirmed. Postoperative course was uneventful and serum HCG was undetectable at the fourth week after surgery. Awareness about this rare form of ectopic pregnancy is observational and mainly comes from reported cases. A high index of suspicion is needed for early diagnosis and intervention.
{"title":"A rare case of broad ligament ectopic pregnancy","authors":"S. Ganta, S. S.K","doi":"10.24327/IJRSR.2017.0805.0283","DOIUrl":"https://doi.org/10.24327/IJRSR.2017.0805.0283","url":null,"abstract":"Ectopic pregnancy continues to be an obstetric challenge despite the advancement of technology. Abdominal pregnancy is rare (1in 10,000 births) and extremely serious form of extra uterine pregnancy. It can pose a major diagnostic hurdle with many being diagnosed only intra-operatively. We report a case of a 26 year old nullipara who presented with 6 weeks of amenorrhea with abdominal pain since 5 hours and one episode of syncope. She was hemodynamically unstable, routine ultrasound revealed an empty uterus with free fluid in the abdomen. It was diagnosed as a ruptured ectopic pregnancy and taken up for an emergency laparotomy. She had a right broad ligament ectopic pregnancy which had ruptured. Both the tubes, ovaries and uterus was found intact. Excision of the ruptured ectopic mass on the right side of the broad ligament was done. The specimen was sent for histopathological examination and confirmed. Postoperative course was uneventful and serum HCG was undetectable at the fourth week after surgery. Awareness about this rare form of ectopic pregnancy is observational and mainly comes from reported cases. A high index of suspicion is needed for early diagnosis and intervention.","PeriodicalId":14198,"journal":{"name":"International journal of recent scientific research","volume":"19 1","pages":"17108-17110"},"PeriodicalIF":0.0,"publicationDate":"2017-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80447207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-28DOI: 10.24327/IJRSR.2017.0805.0302
A. Muthukumar, R. Sundaraganapathy, S. Suganthi, T. Ramu, S. Mohan
The main aim of this study was to evaluate the incidence of ADRs, the patients who are receiving or taking antihypertensive medications. ADR monitoring is an important part of post marketing surveillance which helps in generating data safety of medications. Main aim to ADRs monitoring is to the promoting rational use of drugs, safe use of medicines improving patient care, improving public health. This was a prospective, observational, voluntary reporting study. Study was conducted in and around Coimbatore. Samples are collected in all age group. We are taken support of ‘Suspected Adverse Drug Reaction Reporting form from IPC to collect samples. A total of 34 adverse drug reactions were observed in hypertensive patients during the 3 months study. A high percentage of adverse drug reaction occurred in middle age and female patients. Combination therapy was high occurrence of adverse drug reaction as compared to immunotherapy. Cardiovascular adverse drug reactions constituted a major component, followed by gastrointestinal and respiratory complaints. Beta-blockers were the drug category associated with majority of adverse drug reaction, followed by angiotensin. The present evaluation has revealed opportunities or interventions especially or avoidable ADRs which will help in promoting safer drug use, information to the healthcare professionals. Improve the quality of patient care and educate to increase awareness.
{"title":"A pharmacovigilance study on drugs used in the treatment and management of hypertension in tirupur zone","authors":"A. Muthukumar, R. Sundaraganapathy, S. Suganthi, T. Ramu, S. Mohan","doi":"10.24327/IJRSR.2017.0805.0302","DOIUrl":"https://doi.org/10.24327/IJRSR.2017.0805.0302","url":null,"abstract":"The main aim of this study was to evaluate the incidence of ADRs, the patients who are receiving or taking antihypertensive medications. ADR monitoring is an important part of post marketing surveillance which helps in generating data safety of medications. Main aim to ADRs monitoring is to the promoting rational use of drugs, safe use of medicines improving patient care, improving public health. This was a prospective, observational, voluntary reporting study. Study was conducted in and around Coimbatore. Samples are collected in all age group. We are taken support of ‘Suspected Adverse Drug Reaction Reporting form from IPC to collect samples. A total of 34 adverse drug reactions were observed in hypertensive patients during the 3 months study. A high percentage of adverse drug reaction occurred in middle age and female patients. Combination therapy was high occurrence of adverse drug reaction as compared to immunotherapy. Cardiovascular adverse drug reactions constituted a major component, followed by gastrointestinal and respiratory complaints. Beta-blockers were the drug category associated with majority of adverse drug reaction, followed by angiotensin. The present evaluation has revealed opportunities or interventions especially or avoidable ADRs which will help in promoting safer drug use, information to the healthcare professionals. Improve the quality of patient care and educate to increase awareness.","PeriodicalId":14198,"journal":{"name":"International journal of recent scientific research","volume":"41 1","pages":"17196-17199"},"PeriodicalIF":0.0,"publicationDate":"2017-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82452479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-28DOI: 10.24327/IJRSR.2017.0805.0233
L. Mosha
Vast majority of African people cannot afford adequate housing. UNCHS define adequate housing as the one with acceptable level of privacy, space, physical accessibility, security, security of tenure, structural stability, durability, lighting, heating, ventilation and basic social infrastructural services. About 50% of African population is currently urban dwellers out of which 75% cannot afford formal housing. The concept of affordable housing was conceived with an aim of saving the low income earners and the poor to access formal housing especially in poor countries. Tanzania is one of the poor countries with Gross Domestic Product per capita income record of 842.37 US$ in 2015 and defines affordable housing as the one which can adequately shelter all people below and above the poverty line. Literature review was carried out to understand country’s economies and individual’s affordability levels in housing. Field surveys assisted to learn various housing scenarios in rural and urban areas; as well as planned and unplanned urban housing in Tanzania. This study has found out that 7.2% and 21.5% of Tanzanian households were below the food poverty line and basic needs poverty line respectively and they cannot afford adequate housing. The low income earners who are not necessarily in these percentages can hardly afford adequate formal housing because they cannot easily access financial institutions. Consequently formal housing units produced by National Housing Corporation and other commercial housing developers are bought by high income earners. The affordable housing concept is practically unaffordable housing concept to the targeted people. Policy makers, Spatial Planners and Architects should redefine affordable housing and propose pragmatic decent housing approaches to realistically assist the low income earners in poor countries.
{"title":"Questioning the concept of affordable housing - affordable to who in tanzania?","authors":"L. Mosha","doi":"10.24327/IJRSR.2017.0805.0233","DOIUrl":"https://doi.org/10.24327/IJRSR.2017.0805.0233","url":null,"abstract":"Vast majority of African people cannot afford adequate housing. UNCHS define adequate housing as the one with acceptable level of privacy, space, physical accessibility, security, security of tenure, structural stability, durability, lighting, heating, ventilation and basic social infrastructural services. About 50% of African population is currently urban dwellers out of which 75% cannot afford formal housing. The concept of affordable housing was conceived with an aim of saving the low income earners and the poor to access formal housing especially in poor countries. Tanzania is one of the poor countries with Gross Domestic Product per capita income record of 842.37 US$ in 2015 and defines affordable housing as the one which can adequately shelter all people below and above the poverty line. Literature review was carried out to understand country’s economies and individual’s affordability levels in housing. Field surveys assisted to learn various housing scenarios in rural and urban areas; as well as planned and unplanned urban housing in Tanzania. This study has found out that 7.2% and 21.5% of Tanzanian households were below the food poverty line and basic needs poverty line respectively and they cannot afford adequate housing. The low income earners who are not necessarily in these percentages can hardly afford adequate formal housing because they cannot easily access financial institutions. Consequently formal housing units produced by National Housing Corporation and other commercial housing developers are bought by high income earners. The affordable housing concept is practically unaffordable housing concept to the targeted people. Policy makers, Spatial Planners and Architects should redefine affordable housing and propose pragmatic decent housing approaches to realistically assist the low income earners in poor countries.","PeriodicalId":14198,"journal":{"name":"International journal of recent scientific research","volume":"62 4 1","pages":"16866-16871"},"PeriodicalIF":0.0,"publicationDate":"2017-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90141309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-28DOI: 10.24327/ijrsr.2017.0805.0312
Avni Jain, Vinaya Bhat, C. Hegde
Background: Prevention of crestal bone loss by inward shifting of the implant abutment junction has gained popularity among implant manufactures over the last few years. However, effect of stepping down the size of implant platform on crestal bone loss is not known. Objective of this review article is to discuss the concept of platform switching and shifting. Purpose: The purpose of this article is to discuss the literature dealing with the platform switching and platform shifting concept. Materials and Methods: Thorough literature search using PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, Web of Sciences, AMED (Ovid) was done. Results: Literature search revealed studies involving concepts of platform switching and platform shifting. Conclusion: Effect of platform switching on crestal bone loss is very well documented as compared to platform shifting.
背景:在过去的几年中，通过向内移动种植体基台连接处来预防牙冠骨丢失在种植体制造商中越来越受欢迎。然而，缩小种植平台大小对冠骨丢失的影响尚不清楚。本文的目的是讨论平台切换和移位的概念。目的:本文的目的是讨论有关平台切换和平台转换概念的文献。材料和方法:使用PubMed、Cochrane中央对照试验注册中心(Central)、EMBASE、Web of Sciences、AMED (Ovid)进行全面的文献检索。结果:文献检索揭示了涉及平台切换和平台转移概念的研究。结论:与平台移动相比，平台切换对嵴骨丢失的影响已被充分证明。
{"title":"Oral periimplant bone loss: platform switching or shifting? – a review","authors":"Avni Jain, Vinaya Bhat, C. Hegde","doi":"10.24327/ijrsr.2017.0805.0312","DOIUrl":"https://doi.org/10.24327/ijrsr.2017.0805.0312","url":null,"abstract":"Background: Prevention of crestal bone loss by inward shifting of the implant abutment junction has gained popularity among implant manufactures over the last few years. However, effect of stepping down the size of implant platform on crestal bone loss is not known. Objective of this review article is to discuss the concept of platform switching and shifting. Purpose: The purpose of this article is to discuss the literature dealing with the platform switching and platform shifting concept. Materials and Methods: Thorough literature search using PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, Web of Sciences, AMED (Ovid) was done. Results: Literature search revealed studies involving concepts of platform switching and platform shifting. Conclusion: Effect of platform switching on crestal bone loss is very well documented as compared to platform shifting.","PeriodicalId":14198,"journal":{"name":"International journal of recent scientific research","volume":"307 1","pages":"17239-17241"},"PeriodicalIF":0.0,"publicationDate":"2017-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89050158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-28DOI: 10.24327/IJRSR.2017.0805.0300
Ibarra J.P, M. Velarde, E. Olmos, A. Alvarado
{"title":"Sustainable oriented innovation in the hotel industry of mazatlán, méxico","authors":"Ibarra J.P, M. Velarde, E. Olmos, A. Alvarado","doi":"10.24327/IJRSR.2017.0805.0300","DOIUrl":"https://doi.org/10.24327/IJRSR.2017.0805.0300","url":null,"abstract":"","PeriodicalId":14198,"journal":{"name":"International journal of recent scientific research","volume":"36 1","pages":"17183-17191"},"PeriodicalIF":0.0,"publicationDate":"2017-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74271444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-28DOI: 10.24327/IJRSR.2017.0805.0287
N. Sharma
{"title":"Assessment of biofuel potential in india","authors":"N. Sharma","doi":"10.24327/IJRSR.2017.0805.0287","DOIUrl":"https://doi.org/10.24327/IJRSR.2017.0805.0287","url":null,"abstract":"","PeriodicalId":14198,"journal":{"name":"International journal of recent scientific research","volume":"16 1","pages":"17125-17127"},"PeriodicalIF":0.0,"publicationDate":"2017-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82103045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-28DOI: 10.24327/ijrsr.2017.0805.0250
Mohammed M Al Abdaly, M. Almalki, K. Saleh
Background: The relation between dental restorations and periodontal health are more important so the healthy periodontal status requires correction of dental restorations that is mandatory for the protection of periodontal tissues. Aims of the study: The present study was designed to evaluate the effect of some iatrogenic factors on a cytomorphometric analysis of gingival cells and periodontal status among diabetic patients. Subjects and Methods: The sample of the present study consisted of three hundred diabetic patients and they were divided into three equal groups 100 patients per group control group, composite fillings group and metal ceramic crown group. They were selected from the clinics of the college of dentistry King Khalid University. Plaque index (PI), gingival index (GI), and clinical attachment loss (CAL) were recorded. The cytomorphometric changes were evaluated by the Cytological investigation (MN Apoptotic and Necrotic Test). The results were collected and analyzed by ANOVA test. Results: In the present study there were significant differences were detected in all clinical parameters in the samples of the study groups where there was an increase in (PI), (GI), and (CAL) of study groups compared to control group. In a cytomorphometric analysis of gingival cells, there was no significant increase of apoptosis and necrosis compared to control group. Conclusions: The results of a current study revealed that there were increased gingival inflammation and attachment loss in both study groups compared to the control group, but there was a significance induction of micronuclei formation in all groups.
{"title":"The influence of some iatrogenic factors on a cytomorphometric analysis of gingival cells and periodontal status among diabetic patients","authors":"Mohammed M Al Abdaly, M. Almalki, K. Saleh","doi":"10.24327/ijrsr.2017.0805.0250","DOIUrl":"https://doi.org/10.24327/ijrsr.2017.0805.0250","url":null,"abstract":"Background: The relation between dental restorations and periodontal health are more important so the healthy periodontal status requires correction of dental restorations that is mandatory for the protection of periodontal tissues. Aims of the study: The present study was designed to evaluate the effect of some iatrogenic factors on a cytomorphometric analysis of gingival cells and periodontal status among diabetic patients. Subjects and Methods: The sample of the present study consisted of three hundred diabetic patients and they were divided into three equal groups 100 patients per group control group, composite fillings group and metal ceramic crown group. They were selected from the clinics of the college of dentistry King Khalid University. Plaque index (PI), gingival index (GI), and clinical attachment loss (CAL) were recorded. The cytomorphometric changes were evaluated by the Cytological investigation (MN Apoptotic and Necrotic Test). The results were collected and analyzed by ANOVA test. Results: In the present study there were significant differences were detected in all clinical parameters in the samples of the study groups where there was an increase in (PI), (GI), and (CAL) of study groups compared to control group. In a cytomorphometric analysis of gingival cells, there was no significant increase of apoptosis and necrosis compared to control group. Conclusions: The results of a current study revealed that there were increased gingival inflammation and attachment loss in both study groups compared to the control group, but there was a significance induction of micronuclei formation in all groups.","PeriodicalId":14198,"journal":{"name":"International journal of recent scientific research","volume":"9 1","pages":"16945-16948"},"PeriodicalIF":0.0,"publicationDate":"2017-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85671856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-28DOI: 10.24327/IJRSR.2017.0805.0305
S. S. Reddy, S. Nagunath
Self medication is a major form of self-care. It involves the use of medicinal products by the consumer to treat self recognized disorder, symptoms, recurrent disease or minor health problems. It is independent of age for both males and females(5). Medicines for self medication are often called Over the Counter (OTC) drug, which are available without a Doctors prescription through pharmacies, mostly in the less developed countries. Recent development of the pharmaceutical companies contribute to a wide spread availability of OTC Medicine. The study was conducted in Rural and Urban areas of Kodad, Telangana state, nalgonda dist, 508206. In these areas there are several type of people for eg: some of the people are educated, some are illiteracy ,some are workers etc. The study was done in for the 200 people of different age groups of male and female. It was found that the urban people (54.74%) of male, (12%) of the female are taking self medication .In the rural people the (45.26%)of the male and (43%) of the female are taking self medication and among the educated people those who are studying ssc below they are taking self medication for about (24.21%) in male and (29.09%) are female and those who are studying 12 class (14.75%) male and (26%) of female students among the degree students in male are (58.94%) and the female are (38.18%). The students of above degree in male are about (2.10%)and (12.72%) of female students and it was seen that mostly (17.89%) of male and (10.90%) of female taking self medication for fever and for both fever and headache are (32.65%) of male and (25.26%) of female are taking self medication. For fever and acidity (10.52%)of male and (1.81%) of female are taking medication.Mostly (2.10%) of male and (3.15%) of female taking self medication for acidity and it was seen that people who are taking self medication they are using common sources of medication like pharmacy store (20%) and from grocery shop is (29.09%), and from other persons is about (27.27%). It was observed that since >5years he (75%) of the people are taking self medication and (50%) of the peoplethey are taking from 2-5 years,and (65%) of people taking self medication more than 2years. It was found that most of the people are taking self medication because of their personal convenience (45%), and also due to the long wait for check up (20%) and some of other reasons like illness is minor, lack of time, lack of money and others. It also found that (41.05%) of male and (23.63%) of female are having knowledge about the drugs, and (53.68%) of male and (74.54%) of female are not having knowledge about the drugs. It was observed that complications occurred due to self medication about (12.63%) of male and female didn’t occurred any complications and (24%) of the people given self medication to the children and (82%) of people not given self medication to their children.
{"title":"Study on use of self medication among rural and urban people of kodad, telangana, india","authors":"S. S. Reddy, S. Nagunath","doi":"10.24327/IJRSR.2017.0805.0305","DOIUrl":"https://doi.org/10.24327/IJRSR.2017.0805.0305","url":null,"abstract":"Self medication is a major form of self-care. It involves the use of medicinal products by the consumer to treat self recognized disorder, symptoms, recurrent disease or minor health problems. It is independent of age for both males and females(5). Medicines for self medication are often called Over the Counter (OTC) drug, which are available without a Doctors prescription through pharmacies, mostly in the less developed countries. Recent development of the pharmaceutical companies contribute to a wide spread availability of OTC Medicine. The study was conducted in Rural and Urban areas of Kodad, Telangana state, nalgonda dist, 508206. In these areas there are several type of people for eg: some of the people are educated, some are illiteracy ,some are workers etc. The study was done in for the 200 people of different age groups of male and female. It was found that the urban people (54.74%) of male, (12%) of the female are taking self medication .In the rural people the (45.26%)of the male and (43%) of the female are taking self medication and among the educated people those who are studying ssc below they are taking self medication for about (24.21%) in male and (29.09%) are female and those who are studying 12 class (14.75%) male and (26%) of female students among the degree students in male are (58.94%) and the female are (38.18%). The students of above degree in male are about (2.10%)and (12.72%) of female students and it was seen that mostly (17.89%) of male and (10.90%) of female taking self medication for fever and for both fever and headache are (32.65%) of male and (25.26%) of female are taking self medication. For fever and acidity (10.52%)of male and (1.81%) of female are taking medication.Mostly (2.10%) of male and (3.15%) of female taking self medication for acidity and it was seen that people who are taking self medication they are using common sources of medication like pharmacy store (20%) and from grocery shop is (29.09%), and from other persons is about (27.27%). It was observed that since >5years he (75%) of the people are taking self medication and (50%) of the peoplethey are taking from 2-5 years,and (65%) of people taking self medication more than 2years. It was found that most of the people are taking self medication because of their personal convenience (45%), and also due to the long wait for check up (20%) and some of other reasons like illness is minor, lack of time, lack of money and others. It also found that (41.05%) of male and (23.63%) of female are having knowledge about the drugs, and (53.68%) of male and (74.54%) of female are not having knowledge about the drugs. It was observed that complications occurred due to self medication about (12.63%) of male and female didn’t occurred any complications and (24%) of the people given self medication to the children and (82%) of people not given self medication to their children.","PeriodicalId":14198,"journal":{"name":"International journal of recent scientific research","volume":"157 1","pages":"17209-17213"},"PeriodicalIF":0.0,"publicationDate":"2017-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86340268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-28DOI: 10.24327/ijrsr.2017.0805.0237
A. Nejati, H. Singh, A. Naghdi
Objective: The present study is aimed to assess drug induced QT-interval prolongation in hospital inpatients through ECG data, predictors of risk factor for QT-interval prolongation and drug-drug interactions. Methodology: It is a prospective observational study conducted in inpatient setting. The data collected in pre design data collection form for 110 patients, who are assessed for the period of six months. The prescription with at least one QT-interval prolonging drugs were considered for this study. The collected data included demographics, mean change in QT-interval with drugs, ECG data and safety analysis data. Result: The total number of patients screened was 110. Among the study patients most of them 50.91% were older age. Major comorbidities were diabetes mellitus 39(35.45%) and hypertension 36(32.72%). There was a high prevalence (46.45%) of QT-interval prolongation. The mean QTc in prolonged group was 495±34.4ms.Ondansetron (61.18%), Metronidazole (58.18%), Ciprofloxacin (20.9%), Azithromycin (16.36%) and Domperidone (11.81%) were associated with marked QTc-interval prolongation. Female sex, longer hospitalization, electrolyte abnormalities and older age were associated with drug induced QT-interval prolongation.97 (88.18%) prescriptions showed drug interaction involving QT-interval prolongation. The most common drug interaction was found to be between ondansetron and metronidazole in 41 prescription followed by ondansetron and ciprofloxacin in 15 prescription. Of the 97 interventions proposed, the most frequent suggestion was on stop/avoid/dose adjustment (13.40%) followed by ECG monitoring (10.40%). 16.49% of interventions were accepted and therapy was changed. Conclusion: This study demonstrates the high prevalence of a prolonged QTinterval in patients. Cardiac drugs and antibiotics were frequently involved in drug induced QT-interval prolongation. A simple ECG and a calculated QT interval can be used to plan management and caution us on probable electrolyte abnormalities and drug therapies. The current study demonstrated the importance of routine medication review and the need of a pharmacist in a multidisciplinary team.
{"title":"A prospective study on assessment of drug induced qt interval prolongationin inpatient department at a tertiary care hospital","authors":"A. Nejati, H. Singh, A. Naghdi","doi":"10.24327/ijrsr.2017.0805.0237","DOIUrl":"https://doi.org/10.24327/ijrsr.2017.0805.0237","url":null,"abstract":"Objective: The present study is aimed to assess drug induced QT-interval prolongation in hospital inpatients through ECG data, predictors of risk factor for QT-interval prolongation and drug-drug interactions. Methodology: It is a prospective observational study conducted in inpatient setting. The data collected in pre design data collection form for 110 patients, who are assessed for the period of six months. The prescription with at least one QT-interval prolonging drugs were considered for this study. The collected data included demographics, mean change in QT-interval with drugs, ECG data and safety analysis data. Result: The total number of patients screened was 110. Among the study patients most of them 50.91% were older age. Major comorbidities were diabetes mellitus 39(35.45%) and hypertension 36(32.72%). There was a high prevalence (46.45%) of QT-interval prolongation. The mean QTc in prolonged group was 495±34.4ms.Ondansetron (61.18%), Metronidazole (58.18%), Ciprofloxacin (20.9%), Azithromycin (16.36%) and Domperidone (11.81%) were associated with marked QTc-interval prolongation. Female sex, longer hospitalization, electrolyte abnormalities and older age were associated with drug induced QT-interval prolongation.97 (88.18%) prescriptions showed drug interaction involving QT-interval prolongation. The most common drug interaction was found to be between ondansetron and metronidazole in 41 prescription followed by ondansetron and ciprofloxacin in 15 prescription. Of the 97 interventions proposed, the most frequent suggestion was on stop/avoid/dose adjustment (13.40%) followed by ECG monitoring (10.40%). 16.49% of interventions were accepted and therapy was changed. Conclusion: This study demonstrates the high prevalence of a prolonged QTinterval in patients. Cardiac drugs and antibiotics were frequently involved in drug induced QT-interval prolongation. A simple ECG and a calculated QT interval can be used to plan management and caution us on probable electrolyte abnormalities and drug therapies. The current study demonstrated the importance of routine medication review and the need of a pharmacist in a multidisciplinary team.","PeriodicalId":14198,"journal":{"name":"International journal of recent scientific research","volume":"22 7-8 1","pages":"16886-16889"},"PeriodicalIF":0.0,"publicationDate":"2017-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83694752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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