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Study on consumption of fast food and its association with BMI among medical students in a tertiary care center of eastern India 印度东部某三级保健中心医学生快餐消费与BMI关系的研究
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/ijnpnd.ijnpnd_2_23
Sumita Sharma, Lipilekha Patnaik, Sumitra Pattnaik, Gurukrushna Mohapatra
Background: Food that is instantly cooked and served at establishments is known as fast food. It consists of foods like pizza, ice cream, chicken nuggets, French fries, fried chicken, sandwiches, and chips. Medical students are no exception to the fact that today’s youth adhere intensely and fashionably to the fast-food culture. As medico has to work in stressful routine that seriously affects the eating habits and different food pattern. The aim of this study was to determine the prevalence regarding consumption of fast food among medical students, its pattern, and to explore various factors influencing the students for it. Objectives: To study the consumption of fast food and its association with BMI among medical students in a tertiary care center of eastern India. Methodology: It is a cross-sectional study conducted in IMS & SUM Hospital, Bhubaneswar, Odisha during the month of October 2021 to January 2022. All the undergraduate MBBS students were taken as study population. A structured questionnaire was developed as study tool to capture all data, which were analyzed through SPSS version 26. Results: A total of 177 students participated in the study, among which 56% were male and rest 44% were female students. The mean age was found as 19.67 ± 3.33 years. Though majority students (93.8%) were being aware of the fact that consuming fast food leads to many diseases and disability, most of the students continue to eat fast food. It may be due to reasons of tasteless food at hostel canteen (34.69%), followed by new taste of fast food with company (30.25%) and to avoid wastage of time (4.07%). Conclusion: The superintendent of the hostel should be mindful of ensuring that all students receive food that is of a high standard. Because common people follow the example set by future doctors, medical professionals must be aware of this for the sake of their own well-being. In restaurants, wholesome snacks can take the place of deep-fried dishes. Government and media should support these channels. By enacting strict restrictions to control the marketing of fast meals in the Indian market, the consumption of fast food by youngsters can be decreased. Levying a high fee on manufactured and imported prepared foods. Medical students’ choices of low-fat menu items and the amount of food they order may be limited by nutritional labelling of food.
背景:在餐馆里立即煮熟并供应的食物被称为快餐。它包括披萨、冰淇淋、鸡块、炸薯条、炸鸡、三明治和薯条等食物。医学生也不例外,今天的年轻人强烈而时尚地坚持快餐文化。由于医生必须在紧张的日常工作中工作,这严重影响了饮食习惯和不同的饮食模式。本研究旨在了解医学生快餐消费的流行程度、模式,并探讨影响医学生快餐消费的各种因素。目的:研究印度东部某三级保健中心医学生快餐消费及其与BMI的关系。方法:这是一项在IMS进行的横断面研究;在2021年10月至2022年1月期间,在奥里萨邦布巴内斯瓦尔SUM医院。以所有MBBS本科生为研究对象。采用结构化问卷作为研究工具来获取所有数据,并通过SPSS version 26对数据进行分析。结果:共有177名学生参与研究,其中男生占56%,女生占44%。平均年龄19.67±3.33岁。虽然大多数学生(93.8%)意识到吃快餐会导致许多疾病和残疾,但大多数学生继续吃快餐。可能是由于宿舍食堂的食物无味(34.69%),其次是与公司一起快餐的新口味(30.25%)和避免浪费时间(4.07%)。结论:宿舍的管理者应该注意确保所有学生都能得到高标准的食物。因为普通人都以未来的医生为榜样,所以医疗专业人员必须意识到这一点,为了他们自己的幸福。在餐馆里,健康的小吃可以代替油炸食品。政府和媒体应该支持这些渠道。通过制定严格的限制来控制快餐在印度市场的营销,可以减少年轻人对快餐的消费。对制造和进口的预制食品征收高额费用。医学生对低脂菜单的选择和他们点的食物数量可能会受到食物营养标签的限制。
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引用次数: 0
Vanillic acid exhibits potent antiproliferative and free radical scavenging effects under in vitro conditions 香草酸在体外条件下显示出有效的抗增殖和自由基清除作用
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/ijnpnd.ijnpnd_29_23
Saravanan Surya, Palanisamy Sampathkumar, Shanmugam M. Sivasankaran, Manoharan Pethanasamy, Chakravarthy Elanchezhiyan, Balasubramaniam Deepa, Shanmugam Manoharan
Cells endure oxidative stress as a result of an imbalance between the status of body’s reactive oxygen species (ROS) and antioxidants. Higher production of ROS or weak antioxidant defense mechanism in the cell could lead to various pathological disorders, including carcinogenesis. The present study investigated the in vitro free radical scavenging activity and antiproliferative efficacy of vanillic acid using a spectrum of radical scavenging assays and cytotoxic assays, respectively. Vanillic acid’s antioxidant ability was investigated using in vitro antioxidant assays such as 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), hydroxyl, and superoxide radical scavenging assays. The current study observed an excellent free radical scavenging capacity of vanillic acid, which was comparable to that of ascorbic acid (reference drug). The antiproliferative effect of vanillic acid was assessed in mammary cancer cells (Michigan Cancer Foundation-7 [MCF-7]) by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, ROS generation potential, changes in mitochondrial membrane potential, and by evaluating its apoptotic induction potential. The cell viability of breast cancer cells was drastically decreased by vanillic acid, and its antiproliferative potential in MCF-7 cells could be due to its ability to induce excessive generation of ROS and its apoptotic induction potential. The present investigation thus explores antioxidant and antiproliferative properties of vanillic acid under in vitro conditions.
由于体内活性氧(ROS)和抗氧化剂状态的不平衡,细胞承受氧化应激。细胞中ROS的产生过高或抗氧化防御机制薄弱可导致多种病理障碍,包括致癌。本研究分别采用自由基清除光谱和细胞毒性光谱研究了香草酸的体外自由基清除活性和抗增殖作用。采用2,2-二苯基-1-吡啶肼(DPPH)、2,2 ' -氮基-双(3-乙基苯并噻唑-6-磺酸)(ABTS)、羟基和超氧自由基清除等体外抗氧化实验研究了香草酸的抗氧化能力。本研究发现香草酸具有与抗坏血酸(参比药物)相当的清除自由基能力。采用3-(4,5-二甲基噻唑-2-酰基)-2,5-二苯基溴化四唑(MTT)测定、ROS生成电位、线粒体膜电位变化及诱导凋亡电位评估香草酸在乳腺癌细胞中的抗增殖作用(Michigan cancer Foundation-7 [MCF-7])。香草酸可显著降低乳腺癌细胞的活力,其在MCF-7细胞中的抗增殖作用可能是由于其诱导ROS过度生成的能力和诱导凋亡的潜力。因此,本研究探讨了香草酸在体外条件下的抗氧化和抗增殖特性。
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引用次数: 0
Modified Nutrition Risk in Critically Ill (m-NUTRIC) score to assess nutritional status and outcome in patients of chronic kidney disease: 2-year cross-sectional study 危重患者改良营养风险(m-NUTRIC)评分评估慢性肾病患者营养状况和预后:2年横断面研究
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/ijnpnd.ijnpnd_9_23
Prerna Verma, Sunil Kumar, Neha Phate, Sourya Acharya, Anil Wanjari, Shilpa Bawankule, Sachin Agrawal
Introduction: Chronic kidney disease (CKD) is a major health concern in India and has high prevalence, morbidity, and mortality due to significant percentages of subjects with poor socioeconomic status as well as poor management of health resources. Many apparatuses are available to assess nutrition status among patients of CKD. This study was conducted to identify nutritional risk in CKD patients using a modified Nutrition Risk in Critically ill (m-NUTRIC) score without using interleukin-6 values. Method: This prospective observational study was conducted at a tertiary care teaching hospital for a time period of 2 years from 2020 to 2022. The modification of diet in renal disease approach was used for the staging of the CKD. m-NUTRIC scores were calculated and scores ≥5 were graded in high-risk categories and were associated with adverse outcomes, whereas scores <5 were categorized as low risk. Result: Among 250 patients with CKD enrolled, 65 patients were in the age group 18 to 40 years having a mean m-NUTRIC score of 4.46 ± 1.76; in the age group 40 to 60 years 5.18 ± 1.67; and in the age group older than 60 years 5.88 ± 1.77. The mean (standard deviation [SD]) m-NUTRIC score in hemodialysis group was 5.69 ± 1.63 and in nonhemodialysis group was 4.15 ± 1.66. At m-NUTRIC cutoff of 5, predicted hemodialysis is having 66% specificity and 77% sensitivity. It predicts mortality with a sensitivity of 93% and a specificity of 89% at a cutoff of m-NUTRIC of 6. Conclusion: This study showed that m-NUTRIC score may be an important tool that determines requirement of hemodialysis and mortality in CKD patients. Moreover, these scores were higher in stages 4 and 5 of CKD.
慢性肾脏疾病(CKD)是印度的主要健康问题,由于社会经济地位低下以及卫生资源管理不善,其患病率、发病率和死亡率都很高。许多仪器可用于评估CKD患者的营养状况。本研究是在不使用白细胞介素-6值的情况下,使用改良的危重症营养风险(m-NUTRIC)评分来确定CKD患者的营养风险。方法:本前瞻性观察研究于2020 - 2022年在某三级保健教学医院进行,为期2年。在CKD的分期中采用了肾脏疾病饮食改变的方法。计算m-NUTRIC评分,得分≥5分为高危类别并与不良结局相关,而得分<5分为低风险类别。结果:在入选的250例CKD患者中,65例患者年龄在18至40岁之间,平均m-NUTRIC评分为4.46±1.76;40 ~ 60岁年龄组5.18±1.67;60岁以上年龄组(5.88±1.77)。血液透析组m-NUTRIC评分均值(标准差[SD])为5.69±1.63,非血液透析组m-NUTRIC评分均值为4.15±1.66。在m-NUTRIC临界值为5时,预测血液透析的特异性为66%,敏感性为77%。在m-NUTRIC的临界值为6时,它预测死亡率的灵敏度为93%,特异性为89%。结论:本研究表明m-NUTRIC评分可能是确定CKD患者血液透析需求和死亡率的重要工具。此外,这些评分在CKD的4期和5期更高。
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引用次数: 0
Broca’s Aphasia as an Only Presenting Feature in Neurocysticercosis with Multiple Cysts: A Rare Case Report 布洛卡失语是神经囊虫病多发囊肿的唯一表现:一例罕见病例报告
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/ijnpnd.ijnpnd_21_23
Harshitha Reddy, Divit Shah, Venkat Reddy, Sunil Kumar, Sourya Acharya, Sachin Aggarwal
Neurocysticercosis is a parasitic infection in the brain. Speech involvement is rare in the case of neurocysticercosis. Here we discuss a 60-year-old man with multiple brain cysticercosis who had Broca’s aphasia and responded well to treatment with corticosteroids and albendazole. Lesions affecting the anterior perisylvian speech region cause Broca’s aphasia, which was evident on brain imaging.
神经囊虫病是一种脑部寄生虫感染。神经囊虫病患者很少出现言语障碍。在这里,我们讨论了一个60岁的男性多发性脑囊虫病,他有布洛卡失语症,对皮质类固醇和阿苯达唑治疗反应良好。在脑成像上可以明显地看到,影响前边缘语言区的病变导致了布洛卡失语症。
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引用次数: 0
Comparison of Full Outline of Unresponsiveness (FOUR) and Glasgow Coma Scale (GCS) in Determining Outcome among Patients in Critical Care Units – A Prospective Study 无反应性量表(FOUR)和格拉斯哥昏迷量表(GCS)在确定重症监护病房患者预后中的比较——一项前瞻性研究
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/ijnpnd.ijnpnd_6_23
Anandhi Deva Amirtharaj, Shreedevi Balachandran, Arunodaya Ramarao Gujjar, Judie Arulappan, Sathish Kumar Jaypal
Accurate assessment and monitoring of level of consciousness is fundamental for prompt management and recognising warning signs of deterioration in the patient. The Glasgow coma scale (GCS), a widely used tool was compared with full outline of unresponsiveness (FOUR) score as an alternate tool for assessment and prognostication of the outcome. The purpose of this study aimed to compare and evaluate the accuracy between GCS and FOUR score (FS) tool in the neurological assessment and predicting the functional outcome. Materials and Methods: For this observational study, 131 patients were recruited from two major teaching hospitals in Middle Eastern countries. Data was collected on admission from emergency department and reassessed on day two & four. Patient was followed on discharge and outcome evaluated using the Glasgow outcome scale (GOS). Results: The mean age was 56.39±17.29 (18- 87years) with 83(63.4%) male patients. 93 (71%) patients admitted with neurological problems. In terms of predicting the outcome using the GOS, the area under the ROC curve was 92% (CI- 95%, 0.870-0.975) for FS and 74.73 % (CI-95%, 0.825-0.951) for GCS. The sensitivity and specificity for FS on admission (0.976 & 0.543), day two (0.971 & 0.495) & day four (0.971 & 0.340) and for GCS is (0.918 & 0.370) (0.941 & 0.433) (0.971 & 0.330). Conclusions: The FS tool is precise in predicting power of mortality and is an ideal complementary or substitute tool for GCS.
准确评估和监测意识水平是及时管理和识别患者恶化的警告信号的基础。格拉斯哥昏迷量表(GCS)是一种广泛使用的工具,作为评估和预测结果的替代工具,与无反应性全大纲评分(FOUR)进行比较。本研究的目的是比较和评价GCS和FOUR评分(FS)工具在神经学评估和预测功能预后方面的准确性。材料和方法:在这项观察性研究中,从中东国家的两家主要教学医院招募了131名患者。从急诊科入院时收集数据,并在第二天重新评估;四。患者出院后随访,使用格拉斯哥预后量表(GOS)评估预后。结果:平均年龄56.39±17.29岁(18 ~ 87岁),男性83例(63.4%)。93例(71%)患者因神经系统问题入院。在GOS预测预后方面,FS和GCS的ROC曲线下面积分别为92% (CI-95%, 0.870-0.975)和74.73% (CI-95%, 0.825-0.951)。入院时FS的敏感性和特异性(0.976 &0.543),第二天(0.971 &0.495),第四天(0.971 &0.340), GCS为(0.918 &0.370) (0.941 &(0.971 &0.330)。结论:FS工具对死亡率的预测能力准确,是GCS的理想补充或替代工具。
{"title":"Comparison of Full Outline of Unresponsiveness (FOUR) and Glasgow Coma Scale (GCS) in Determining Outcome among Patients in Critical Care Units – A Prospective Study","authors":"Anandhi Deva Amirtharaj, Shreedevi Balachandran, Arunodaya Ramarao Gujjar, Judie Arulappan, Sathish Kumar Jaypal","doi":"10.4103/ijnpnd.ijnpnd_6_23","DOIUrl":"https://doi.org/10.4103/ijnpnd.ijnpnd_6_23","url":null,"abstract":"Accurate assessment and monitoring of level of consciousness is fundamental for prompt management and recognising warning signs of deterioration in the patient. The Glasgow coma scale (GCS), a widely used tool was compared with full outline of unresponsiveness (FOUR) score as an alternate tool for assessment and prognostication of the outcome. The purpose of this study aimed to compare and evaluate the accuracy between GCS and FOUR score (FS) tool in the neurological assessment and predicting the functional outcome. Materials and Methods: For this observational study, 131 patients were recruited from two major teaching hospitals in Middle Eastern countries. Data was collected on admission from emergency department and reassessed on day two &amp; four. Patient was followed on discharge and outcome evaluated using the Glasgow outcome scale (GOS). Results: The mean age was 56.39±17.29 (18- 87years) with 83(63.4%) male patients. 93 (71%) patients admitted with neurological problems. In terms of predicting the outcome using the GOS, the area under the ROC curve was 92% (CI- 95%, 0.870-0.975) for FS and 74.73 % (CI-95%, 0.825-0.951) for GCS. The sensitivity and specificity for FS on admission (0.976 &amp; 0.543), day two (0.971 &amp; 0.495) &amp; day four (0.971 &amp; 0.340) and for GCS is (0.918 &amp; 0.370) (0.941 &amp; 0.433) (0.971 &amp; 0.330). Conclusions: The FS tool is precise in predicting power of mortality and is an ideal complementary or substitute tool for GCS.","PeriodicalId":14233,"journal":{"name":"International Journal of Nutrition, Pharmacology, Neurological Diseases","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135851825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bibliometric Profile of the World Scientific Production on Thanatology in Nursing: Visibility, Impact, and Alternative Metrics 世界护理学科学成果的文献计量学概况:可见性、影响和替代指标
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/ijnpnd.ijnpnd_11_23
Fran Espinoza-Carhuancho, John Barja-Ore, Frank Mayta-Tovalino
Objective: We will analyze the bibliometric metrics of the global scientific production in thanatology for nursing care. Methods : A cross-sectional and retrospective study with a bibliometric approach evaluated publications indexed in Scopus from 2017 to 2022. MESH terms were selected, and together with the Boolean operators AND OR a search strategy was developed and applied on December 20, 2022. We also analyzed the metadata of the publications included in the study using Elsevier’s Scival program. Results : Scientific production has increased from 29 in 2017 to 48 in 2022. Most of the articles analyzed had national cooperation (45.2%) and single authorship was presented in a lower proportion (9.6%). The United States (55) is the country with the most publications; in addition, South Korea had the lowest production (10) and lowest weighted impact (FWCI: 0.35). The articles are mainly published in first-quartile journals, such as the Journal of Pain and Symptom Management. The University of Toronto has 71% more citations than expected. Lester David and Dadfar Mahboubeh lead the subject with four published articles each. Conclusion : Thanatology in the field of nursing is a topic that has increased in recent years, and its main means of dissemination are the scientific journals of the Q1 and Q2 quartile. The leading country in this area was the United States, while Brazil was the only Latin American country with institutions among the most productive.
目的:分析全球护理学科学成果的文献计量学指标。方法:采用文献计量学方法对2017年至2022年Scopus检索的出版物进行横断面回顾性研究。选择MESH术语,并与布尔运算符and OR一起制定搜索策略,并于2022年12月20日应用。我们还使用爱思唯尔的Scival程序分析了纳入研究的出版物的元数据。结果:科研成果由2017年的29篇增加到2022年的48篇。大部分被分析的文章为国家合作(45.2%),单一作者所占比例较低(9.6%)。美国(55)是发表论文最多的国家;此外,韩国的产量最低(10),加权影响最低(FWCI: 0.35)。文章主要发表在第一四分位数的期刊上,如Journal of Pain and Symptom Management。多伦多大学(University of Toronto)的引用次数比预期高出71%。Lester David和Dadfar Mahboubeh各自发表了四篇文章。结论:死亡学在护理领域是近年来兴起的一个话题,其主要传播手段是Q1和Q2四分位数的科学期刊。在这一领域处于领先地位的国家是美国,而巴西是唯一一个拥有最具生产力机构的拉丁美洲国家。
{"title":"Bibliometric Profile of the World Scientific Production on Thanatology in Nursing: Visibility, Impact, and Alternative Metrics","authors":"Fran Espinoza-Carhuancho, John Barja-Ore, Frank Mayta-Tovalino","doi":"10.4103/ijnpnd.ijnpnd_11_23","DOIUrl":"https://doi.org/10.4103/ijnpnd.ijnpnd_11_23","url":null,"abstract":"Objective: We will analyze the bibliometric metrics of the global scientific production in thanatology for nursing care. Methods : A cross-sectional and retrospective study with a bibliometric approach evaluated publications indexed in Scopus from 2017 to 2022. MESH terms were selected, and together with the Boolean operators AND OR a search strategy was developed and applied on December 20, 2022. We also analyzed the metadata of the publications included in the study using Elsevier’s Scival program. Results : Scientific production has increased from 29 in 2017 to 48 in 2022. Most of the articles analyzed had national cooperation (45.2%) and single authorship was presented in a lower proportion (9.6%). The United States (55) is the country with the most publications; in addition, South Korea had the lowest production (10) and lowest weighted impact (FWCI: 0.35). The articles are mainly published in first-quartile journals, such as the Journal of Pain and Symptom Management. The University of Toronto has 71% more citations than expected. Lester David and Dadfar Mahboubeh lead the subject with four published articles each. Conclusion : Thanatology in the field of nursing is a topic that has increased in recent years, and its main means of dissemination are the scientific journals of the Q1 and Q2 quartile. The leading country in this area was the United States, while Brazil was the only Latin American country with institutions among the most productive.","PeriodicalId":14233,"journal":{"name":"International Journal of Nutrition, Pharmacology, Neurological Diseases","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135851820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-Frequency Hearing Sensitivity Level among Young Adults with Insulin-Dependent and Non-Insulin-Dependent Diabetes Mellitus 胰岛素依赖型和非胰岛素依赖型糖尿病青年患者高频听力敏感性水平
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/ijnpnd.ijnpnd_57_22
Gnana Sekaran, Tamil Selvan Gnanasekaran, Kala Samayan, Kumar JS, Venkataraman Prabhu, Selvarajan G, Muthukumaran G, Ambethkar Suprent, Deepalakshmi K
Diabetes Mellitus (DM) is a metabolic disorder characterized by elevated blood sugar levels. Patients of DM body cells are exposed to excessive amounts of plasma glucose, and the symptoms reported to complicate the sensory hearing organ. Spiral ganglion atrophy, vestibulocochlear nerve myelin sheath degradation, a reduction in the number of spiral lamina nerve fibres, and thickening of the stria vascularis and small arteries capillary walls are all potential chronic auditory repercussions of diabetes. The damage to any part of the hearing mechanism can lead to hearing loss. The present study aimed to investigate the high-frequency hearing sensitivity level among young adults diagnosed with Insulin-dependent and Non-Insulin dependent Diabetes Mellitus. It is an observational study design. Totally 90 participants were included between the age range of 31–40 years and divided into three groups (Control, Insulin-dependent DM, and Non-Insulin dependent DM). Each group had 30 participants. The results indicated that the hearing sensitivity level in high frequencies decreased when compared to lower frequencies. Most of the participants were observed to have reduced hearing sensitivity from mild to moderately severe sensorineural hearing loss. The study concluded that strong evidence that hearing loss may be a sign of DM.
糖尿病(DM)是一种以血糖水平升高为特征的代谢紊乱。糖尿病患者的体细胞暴露于过量的血浆葡萄糖中,据报道症状使感觉听觉器官复杂化。螺旋神经节萎缩,前庭耳蜗神经髓鞘退化,螺旋层神经纤维数量减少,血管纹和小动脉毛细血管壁增厚都是糖尿病潜在的慢性听觉反应。听力机制的任何部分受损都可能导致听力损失。本研究旨在探讨诊断为胰岛素依赖型和非胰岛素依赖型糖尿病的年轻成人的高频听力敏感水平。这是一项观察性研究设计。共纳入90名参与者,年龄在31-40岁之间,分为三组(对照组、胰岛素依赖型糖尿病和非胰岛素依赖型糖尿病)。每组有30名参与者。结果表明,与低频相比,高频的听觉灵敏度水平有所下降。大多数参与者被观察到从轻度到中度重度感音神经性听力损失的听力敏感性降低。该研究得出结论,强有力的证据表明听力损失可能是糖尿病的征兆。
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引用次数: 0
Assessment of peripheral nerve conduction in iron deficiency anemia patients in Indian rural adult population attending a tertiary care hospital 在三级保健医院就诊的印度农村成人缺铁性贫血患者周围神经传导的评估
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/ijnpnd.ijnpnd_19_23
Vaishali M Paunikar, Alka T Rawekar, Suchit A Barapatre
Background: Iron deficiency anemia (IDA) is the most common nutritional deficiency anemia in India. Peripheral neuropathy can result due to iron deficiency as it disrupts myelination and neuronal energetics in neuronal functioning. Nerve conduction studies (NCS) can quantitatively detect peripheral nerve dysfunction. This study was conducted to observe effect of IDA on peripheral nerve conduction velocity in adults using neuroelectrophysiological techniques with the aim to recommend Complete Blood Count for serologic evaluation of patients with peripheral neuropathy in Indian population. Objectives: This study aims to compare motor and sensory nerve conduction study parameters between controls and IDA patients and evaluate the effect of various grades of IDA on motor and sensory nerves. Methodology: 30 newly diagnosed patients of IDA in age group of 20-45 yrs and 30 healthy controls in same age group were recruited in this study. NCS was conducted on bilateral motor and sensory median and ulnar nerves in Neurophysiology laboratory using Neurosoft machine. Neuroelectrophysiological data of both the groups was evaluated and analysed using Student’s unpaired t test. Also, patients were categorised as mild, moderate and severe anemia cases and one way ANOVA was used for comparison among patients with various grades of anemia. Results: CMAP (compound muscle action potential), SNAP (sensory nerve action potential) and nerve conduction velocity (NCV) of bilateral median and ulnar nerves was reduced and DL (distal latency) was increased in bilateral median and ulnar nerves in patients with IDA compared to controls. The results were statistically significant ( p =0.001). A highly significant difference between motor and sensory nerve conduction values between mild, moderate and severe IDA patients was also observed ( p =0.001). Conclusion: The results of the study confirmed peripheral nerves involvement in IDA patients. As severity of anemia increases, peripheral neuropathy worsens. These results can be extrapolated for screening patients with peripheral neuropathy for iron deficiency as a routine part of diagnostic approach for peripheral neuropathy.
背景:缺铁性贫血是印度最常见的营养缺乏性贫血。周围神经病变可导致由于缺铁,因为它破坏髓鞘形成和神经元能量在神经元功能。神经传导研究(NCS)可以定量检测周围神经功能障碍。本研究采用神经电生理技术观察IDA对成人周围神经传导速度的影响,目的是推荐全血细胞计数用于印度人群周围神经病变患者的血清学评估。目的:本研究旨在比较对照组和IDA患者的运动和感觉神经传导研究参数,评价不同级别IDA对运动和感觉神经的影响。方法:本研究招募30例20 ~ 45岁的IDA新诊断患者和30例同年龄段的健康对照者。神经生理学实验室采用Neurosoft机器对双侧运动神经和感觉正中神经、尺神经进行神经神经控制(NCS)。两组的神经电生理数据采用Student 's unpaired t检验进行评估和分析。此外,将患者分为轻度、中度和重度贫血病例,并采用单因素方差分析(one - way ANOVA)对不同级别贫血患者进行比较。结果:与对照组相比,IDA患者双侧正中、尺神经CMAP(复合肌动作电位)、SNAP(感觉神经动作电位)和神经传导速度(NCV)降低,远端潜伏期DL(远端潜伏期)升高。结果具有统计学意义(p =0.001)。轻度、中度和重度IDA患者的运动和感觉神经传导值也有极显著差异(p =0.001)。结论:研究结果证实IDA患者累及周围神经。随着贫血严重程度的增加,周围神经病变加重。这些结果可以推断为筛选缺铁的周围神经病变患者作为周围神经病变诊断方法的常规部分。
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引用次数: 0
Nerve conduction parameters and its correlations with glycemic control and duration in type 2 diabetes mellitus − A cross-sectional study 2型糖尿病患者神经传导参数及其与血糖控制和病程的相关性-一项横断面研究
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/ijnpnd.ijnpnd_18_23
Rafi Mohamed Shaji, Mohammed Abdullah, Divya Nagabushana1, Ashwin Kulkarni, Shaikh Mohammed Aslam S
Background: Diabetic neuropathy is one of the most common microvascular complications of diabetes mellitus (DM) and can lead to a wide array of complications, which are concerning as these are considered a leading cause of disability due to foot ulceration, amputation, gait disturbances, and injuries secondary to falls. Nerve conduction studies (NCS) enable the diagnosis of sensory and motor neuropathy even if the dysfunction is subclinical. This study was conducted to assess the correlation between glycated hemoglobin and duration of diabetes with the parameters of NCS among patients of type 2 DM. Methodology: A cross-sectional study was conducted in a tertiary care center in South India. The study was conducted from November 2022 to February 2023. Sixty patients with type 2 DM who presented to the outpatient department with symptoms of neuropathy were included in the study. Detailed clinical history was taken and clinical examination was done. NCS was conducted in them. The parameters of NCS were correlated with HbA1c and duration of diabetes. The statistical analysis was carried out using the SPSS software version 29.0. Results: Sixty patients with type 2 DM were included in the study. The mean age of type 2 DM patients was 60.92 ± 10.9 years. The mean duration of type 2 DM (in years) was 12.8 ± 6.5. Twenty-three participants (38.3%) had solely an axonal pattern of diabetic neuropathy; whereas 20 (33.3%) participants showed a combined axonal and demyelinating pattern of diabetic neuropathy. There was a significant negative correlation between HbA1c and NCS parameters such as nerve conduction velocity, amplitude, and persistence ( p < 0.001); and a significant positive correlation between HbA1c and NCS parameters such as latency and F -wave latency ( p < 0.001). There was a significant correlation between parameters of NCSs and duration of DM ( p < 0.001). Conclusion: Glycemic control and duration of DM have a significant impact on the nerve conduction parameters. Patients with poor glycemic control have decreased NCS parameters such as velocity, amplitude, and persistence; and increased parameters such as latency and F -wave latency. Strict glycemic control can be reinforced for better management of diabetic neuropathy.
背景:糖尿病神经病变是糖尿病(DM)最常见的微血管并发症之一,可导致多种并发症,这些并发症被认为是由于足部溃疡、截肢、步态障碍和跌倒后继发损伤而导致残疾的主要原因。神经传导研究(NCS)能够诊断感觉和运动神经病变,即使功能障碍是亚临床的。本研究旨在评估2型糖尿病患者中糖化血红蛋白和糖尿病病程与NCS参数之间的相关性。方法:在印度南部的一家三级保健中心进行横断面研究。该研究于2022年11月至2023年2月进行。60例以神经病变症状就诊于门诊的2型糖尿病患者被纳入研究。记录详细的临床病史并进行临床检查。NCS是在他们身上进行的。NCS参数与HbA1c及糖尿病病程相关。采用SPSS 29.0版软件进行统计分析。结果:60例2型糖尿病患者纳入研究。2型糖尿病患者的平均年龄为60.92±10.9岁。2型糖尿病的平均病程(年)为12.8±6.5年。23名参与者(38.3%)只有轴突型糖尿病神经病变;而20名(33.3%)参与者表现出糖尿病神经病变的轴突和脱髓鞘合并模式。HbA1c与NCS参数如神经传导速度、振幅和持续时间呈显著负相关(p <0.001);HbA1c与潜伏期、F波潜伏期等NCS参数呈显著正相关(p <0.001)。NCSs参数与DM病程有显著相关(p <0.001)。结论:血糖控制和糖尿病病程对神经传导参数有显著影响。血糖控制不良的患者NCS参数降低,如速度、幅度和持续时间;增加了延迟和F波延迟等参数。严格的血糖控制可以加强更好地管理糖尿病神经病变。
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引用次数: 0
Self-medication practice among medical students in the context of the COVID-19 pandemic COVID-19大流行背景下医学生自我药疗实践
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/ijnpnd.ijnpnd_27_23
Lavanya Pawar, None Srikanth, Somashekara SC
Background: The rise in trends of self-medication, particularly among medical students without being aware of its consequences, especially during the COVID pandemic, has raised a major concern. Self-medication may lead to unintended consequences, such as adverse events, unnecessary expenses, delay in attending professional evaluation, masking of symptoms, and drug interactions. Aims and Objectives: The aim of the study was to analyze the prevalence, practice, and pattern of self-medication during the COVID-19 pandemic among medical students. Materials and Methods: In October 2022, a cross-sectional questionnaire-based study was conducted using a validated, pretested questionnaire. Information regarding the demographic details, symptoms that led to self-medication, various drugs used, source of drug information, drug used/drug groups used, and reasons for self-medication during COVID-19 were all described in terms of frequency and percentage. Results: In the present study, 80% of the students practiced self-medication. Fever and headache were the most common symptoms for which self-medication was taken. Paracetamol and azithromycin were the most common drugs used for self-medication. Forty-four percent of the students used medical formulas from the previous consultation as the source of drug information, and 16% from the Internet. About 85% of students obtained the drug from a pharmacy. Thirty-two percent of the students self-medicated because they had symptoms of COVID-19 and 29% as a preventive measure. Conclusion: Self-medication was widely practiced by medical students during the COVID-19 pandemic. There is a need to educate medical students through various measures about the rational use of self-medication.
背景:自我药疗的趋势有所上升,尤其是在医学生中,他们没有意识到其后果,特别是在COVID大流行期间,这引起了人们的严重关切。自我用药可能导致意想不到的后果,如不良事件、不必要的费用、参加专业评估的延误、掩盖症状和药物相互作用。目的和目的:本研究的目的是分析2019冠状病毒病疫情期间医学生自我药疗的流行情况、实践和模式。材料与方法:2022年10月,采用一份经过验证的预测问卷进行了一项基于横断面问卷的研究。有关人口统计细节、导致自我药疗的症状、使用的各种药物、药物信息来源、使用的药物/使用的药物群体以及在COVID-19期间自我药疗的原因等信息均以频率和百分比进行了描述。结果:在本研究中,80%的学生进行了自我药疗。发热和头痛是最常见的自我药物治疗症状。对乙酰氨基酚和阿奇霉素是最常用的自我药疗药物。44%的学生使用以前咨询的药物配方作为药物信息的来源,16%的学生使用互联网。大约85%的学生从药店获得药物。32%的学生自我用药是因为他们有COVID-19的症状,29%是作为预防措施。结论:新冠肺炎疫情期间医学生普遍采用自我药疗。有必要通过各种措施对医学生进行合理使用自我药疗的教育。
{"title":"Self-medication practice among medical students in the context of the COVID-19 pandemic","authors":"Lavanya Pawar, None Srikanth, Somashekara SC","doi":"10.4103/ijnpnd.ijnpnd_27_23","DOIUrl":"https://doi.org/10.4103/ijnpnd.ijnpnd_27_23","url":null,"abstract":"Background: The rise in trends of self-medication, particularly among medical students without being aware of its consequences, especially during the COVID pandemic, has raised a major concern. Self-medication may lead to unintended consequences, such as adverse events, unnecessary expenses, delay in attending professional evaluation, masking of symptoms, and drug interactions. Aims and Objectives: The aim of the study was to analyze the prevalence, practice, and pattern of self-medication during the COVID-19 pandemic among medical students. Materials and Methods: In October 2022, a cross-sectional questionnaire-based study was conducted using a validated, pretested questionnaire. Information regarding the demographic details, symptoms that led to self-medication, various drugs used, source of drug information, drug used/drug groups used, and reasons for self-medication during COVID-19 were all described in terms of frequency and percentage. Results: In the present study, 80% of the students practiced self-medication. Fever and headache were the most common symptoms for which self-medication was taken. Paracetamol and azithromycin were the most common drugs used for self-medication. Forty-four percent of the students used medical formulas from the previous consultation as the source of drug information, and 16% from the Internet. About 85% of students obtained the drug from a pharmacy. Thirty-two percent of the students self-medicated because they had symptoms of COVID-19 and 29% as a preventive measure. Conclusion: Self-medication was widely practiced by medical students during the COVID-19 pandemic. There is a need to educate medical students through various measures about the rational use of self-medication.","PeriodicalId":14233,"journal":{"name":"International Journal of Nutrition, Pharmacology, Neurological Diseases","volume":"208 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135851826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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International Journal of Nutrition, Pharmacology, Neurological Diseases
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