Pub Date : 2017-03-01DOI: 10.12983/IJSRK-2017-P0027-0041
Mehrdad Tajabadi, M. Dehghani, S. Foroughi, A. Salajeghe
Problematic soils present a difficult challenge for geotechnical engineering due to the high settlement of the soil structure and the often associated high water table and moisture content. The Deep Soil Mixing (DSM) method, which is a soil stabilization technique, has been commonly applied to improve Different parameters of soil. The application covers on-land and in-water constructions ranging from strengthening the foundation ground of buildings, embankment supports, earth retaining structures, retrofit and renovation of urban infrastructures, liquefaction hazards mitigation, man-made island constructions and seepage control. In this paper important parameters that effect in performance of deep soil mixing (DSM) and different design steps of DSM is examined. In this regard embankment investigates when use of DSM with finite element method. the results shows by increase of diameter and height of columns safety factor and settlement decrease but this parameters effects Up to a certain amount Then it is negligible Effect.
{"title":"Applicability of Deep Soil Mixing for Use in Embankments and Foundation Support","authors":"Mehrdad Tajabadi, M. Dehghani, S. Foroughi, A. Salajeghe","doi":"10.12983/IJSRK-2017-P0027-0041","DOIUrl":"https://doi.org/10.12983/IJSRK-2017-P0027-0041","url":null,"abstract":"Problematic soils present a difficult challenge for geotechnical engineering due to the high settlement of the soil structure and the often associated high water table and moisture content. The Deep Soil Mixing (DSM) method, which is a soil stabilization technique, has been commonly applied to improve Different parameters of soil. The application covers on-land and in-water constructions ranging from strengthening the foundation ground of buildings, embankment supports, earth retaining structures, retrofit and renovation of urban infrastructures, liquefaction hazards mitigation, man-made island constructions and seepage control. In this paper important parameters that effect in performance of deep soil mixing (DSM) and different design steps of DSM is examined. In this regard embankment investigates when use of DSM with finite element method. the results shows by increase of diameter and height of columns safety factor and settlement decrease but this parameters effects Up to a certain amount Then it is negligible Effect.","PeriodicalId":14310,"journal":{"name":"International Journal of Scientific Research in Knowledge","volume":"172 1","pages":"27-41"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82941401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-01DOI: 10.12983/ijsrk-2017-p0042-0049
M. I. Alisah, W. M. Hairudin, Chan Ping Yi, Z. M. Ripin, T. Hern
{"title":"Low Frequency Electromagnetic Structural Vibration Energy Harvester to Power up Wireless Sensor Node","authors":"M. I. Alisah, W. M. Hairudin, Chan Ping Yi, Z. M. Ripin, T. Hern","doi":"10.12983/ijsrk-2017-p0042-0049","DOIUrl":"https://doi.org/10.12983/ijsrk-2017-p0042-0049","url":null,"abstract":"","PeriodicalId":14310,"journal":{"name":"International Journal of Scientific Research in Knowledge","volume":"5 1","pages":"42-49"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78072935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-01DOI: 10.12983/IJSRK-2017-P0011-0019
S. Sarsam, A. Saidi, Anmar L. Jasim
. The subgrade soil is the foundation plate form of the roadway; it should sustain its structural characteristics throughout the design life of the roadway with minimal requirements for maintenance. When Gypseous soil is implemented in the construction of subgrade, problems regarding collapsibility and poor structural capacity usually occur when the subgrade came in touch with excess water. Asphalt stabilization could furnish a proper solution to such problems. In this investigation, an attempt has been made to monitor the variations in compressibility characteristics of asphalt stabilized subgrade soil subjected to 30 cycles of (freezing-thawing) and (heating-cooling). Data have been observed after each 10 cycles, and compared with that of reference mix. Specimens of (75) mm diameter and (20) mm height have been prepared at optimum fluid content with various asphalt emulsion percentages. Testing was carried out using the standard odometer to determine the compressibility characteristics at dry and soaked test conditions. It was concluded that for samples exposed to (10, 20 and 30) cycles of (freezing-thawing), the compression index (Cc) had increased with the increase of cycles in soaked condition but it decreases with increased number of cycles in dry condition. Initial void ratio decreased with number of cycles in dry condition; but remains constant with increased number of cycles in soaked condition. For samples exposed to (10, 20 and 30) cycles of (heating-cooling), (Cc) decreased with the increase of cycles in both soaked and dry condition. Initial void ratio increased with number of cycles while it slightly changed for dry and soaked condition respectively.
{"title":"Monitoring of the Compressibility Characteristics of Asphalt Stabilized Subgrade","authors":"S. Sarsam, A. Saidi, Anmar L. Jasim","doi":"10.12983/IJSRK-2017-P0011-0019","DOIUrl":"https://doi.org/10.12983/IJSRK-2017-P0011-0019","url":null,"abstract":". The subgrade soil is the foundation plate form of the roadway; it should sustain its structural characteristics throughout the design life of the roadway with minimal requirements for maintenance. When Gypseous soil is implemented in the construction of subgrade, problems regarding collapsibility and poor structural capacity usually occur when the subgrade came in touch with excess water. Asphalt stabilization could furnish a proper solution to such problems. In this investigation, an attempt has been made to monitor the variations in compressibility characteristics of asphalt stabilized subgrade soil subjected to 30 cycles of (freezing-thawing) and (heating-cooling). Data have been observed after each 10 cycles, and compared with that of reference mix. Specimens of (75) mm diameter and (20) mm height have been prepared at optimum fluid content with various asphalt emulsion percentages. Testing was carried out using the standard odometer to determine the compressibility characteristics at dry and soaked test conditions. It was concluded that for samples exposed to (10, 20 and 30) cycles of (freezing-thawing), the compression index (Cc) had increased with the increase of cycles in soaked condition but it decreases with increased number of cycles in dry condition. Initial void ratio decreased with number of cycles in dry condition; but remains constant with increased number of cycles in soaked condition. For samples exposed to (10, 20 and 30) cycles of (heating-cooling), (Cc) decreased with the increase of cycles in both soaked and dry condition. Initial void ratio increased with number of cycles while it slightly changed for dry and soaked condition respectively.","PeriodicalId":14310,"journal":{"name":"International Journal of Scientific Research in Knowledge","volume":"44 1","pages":"11-19"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83703574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-01DOI: 10.12983/ijsrk-2017-p0020-0026
G. El-Habaak, M. Askalany, M. Farghaly, M. Abdel-Hakeem
El-Gedida high-Ba iron ore was subjected to microscopic, mineralogical and chemical characterizations followed by chemical leaching using HCl. The microscopic investigations revealed that the textural relationships between barite and iron minerals are complicated, resulting in a difficult liberation during the comminution process. XRD analysis of the studied ore indicated the presence of hematite and goethite as the dominant iron minerals and barite, quartz and halite as gangue minerals. Chemical assays using XRF showed that the investigated ore contains 42.29% Fe2O3 (29.58% Fe total), 36.99% BaO and 16.95% SO3. The pre-treatment operations involved crushing and milling up to -150μm particle size. The processing operation included chemical leaching of 15 gm representative sample of the ground ore using acidic medium of HCl at fixed agitation speed 900 r/m. The leaching was followed by filtration, solvent extraction and precipitation processes. The resultant dual concentrate is divided into iron fraction containing 66.11% Fe with 99.84% iron recovery and barite concentrate containing 66.85% BaO (99.81% recovery) and 30.53% SO3 (99.47% recovery). The resultant iron fraction is accepted as a blast furnace feed charge for the Egyptian Iron & Steel Company, while barite fraction can be used for the oil industry and glassmaking.
{"title":"The Effect of Acid Concentration on the Chemical Leaching of El-Gedida High-Ba Iron Ore, El-Bahariya Oasis, Western Desert, Egypt","authors":"G. El-Habaak, M. Askalany, M. Farghaly, M. Abdel-Hakeem","doi":"10.12983/ijsrk-2017-p0020-0026","DOIUrl":"https://doi.org/10.12983/ijsrk-2017-p0020-0026","url":null,"abstract":"El-Gedida high-Ba iron ore was subjected to microscopic, mineralogical and chemical characterizations followed by chemical leaching using HCl. The microscopic investigations revealed that the textural relationships between barite and iron minerals are complicated, resulting in a difficult liberation during the comminution process. XRD analysis of the studied ore indicated the presence of hematite and goethite as the dominant iron minerals and barite, quartz and halite as gangue minerals. Chemical assays using XRF showed that the investigated ore contains 42.29% Fe2O3 (29.58% Fe total), 36.99% BaO and 16.95% SO3. The pre-treatment operations involved crushing and milling up to -150μm particle size. The processing operation included chemical leaching of 15 gm representative sample of the ground ore using acidic medium of HCl at fixed agitation speed 900 r/m. The leaching was followed by filtration, solvent extraction and precipitation processes. The resultant dual concentrate is divided into iron fraction containing 66.11% Fe with 99.84% iron recovery and barite concentrate containing 66.85% BaO (99.81% recovery) and 30.53% SO3 (99.47% recovery). The resultant iron fraction is accepted as a blast furnace feed charge for the Egyptian Iron & Steel Company, while barite fraction can be used for the oil industry and glassmaking.","PeriodicalId":14310,"journal":{"name":"International Journal of Scientific Research in Knowledge","volume":"37 1","pages":"20-26"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89784821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-01DOI: 10.12983/ijsrk-2017-p0001-0010
S. Aliyu, Emurot Simon Peter, A. Ochan, M. Mohiuddin, Adamu Almustapha Aleiro
Globally healthcare waste has been identified as a major problem that has the potential of impacting negatively on both human health and environment for decades. The study was conducted to assess healthcare waste management practices employed by health workers in health facilities in Bushenyi District western Uganda. The study design adapted was a descriptive and cross sectional type and both quantitative and qualitative methods were used. Twelve out of a total of 38 health facilities present in the district were selected. A range of methods employed for the collection of data included questionnaire survey which targeted 340 stratified randomly selected healthcare workers, formal interviews as well as field observations. The results depicts that majority of the respondents 263 (77.4%) agreed that healthcare waste was been segregated at their facilities while 51 (15%) denied the existence of segregation. However observations revealed that Segregation was applied only to sharps which was collected in special sharp boxes Furthermore 47 (13.8%) of the respondents do not use protective equipment when handling healthcare waste while majority of the respondents 293 (86.2%) have agreed to usage of protective equipment. The use of hands was identified as the most common mode of transportation as indicated 214 (62.9%) of the respondents while open pit burning was identified as the commonest method of waste disposal. Based on the study findings it was revealed that healthcare waste was improperly managed and majority of healthcare workers were not in compliance with Ugandans health workers guide.
{"title":"Assessment of Healthcare Waste Management Practices Employed by Health Workers in Health Facilities in Bushenyi District Western Uganda","authors":"S. Aliyu, Emurot Simon Peter, A. Ochan, M. Mohiuddin, Adamu Almustapha Aleiro","doi":"10.12983/ijsrk-2017-p0001-0010","DOIUrl":"https://doi.org/10.12983/ijsrk-2017-p0001-0010","url":null,"abstract":"Globally healthcare waste has been identified as a major problem that has the potential of impacting negatively on both human health and environment for decades. The study was conducted to assess healthcare waste management practices employed by health workers in health facilities in Bushenyi District western Uganda. The study design adapted was a descriptive and cross sectional type and both quantitative and qualitative methods were used. Twelve out of a total of 38 health facilities present in the district were selected. A range of methods employed for the collection of data included questionnaire survey which targeted 340 stratified randomly selected healthcare workers, formal interviews as well as field observations. The results depicts that majority of the respondents 263 (77.4%) agreed that healthcare waste was been segregated at their facilities while 51 (15%) denied the existence of segregation. However observations revealed that Segregation was applied only to sharps which was collected in special sharp boxes Furthermore 47 (13.8%) of the respondents do not use protective equipment when handling healthcare waste while majority of the respondents 293 (86.2%) have agreed to usage of protective equipment. The use of hands was identified as the most common mode of transportation as indicated 214 (62.9%) of the respondents while open pit burning was identified as the commonest method of waste disposal. Based on the study findings it was revealed that healthcare waste was improperly managed and majority of healthcare workers were not in compliance with Ugandans health workers guide.","PeriodicalId":14310,"journal":{"name":"International Journal of Scientific Research in Knowledge","volume":"20 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75136819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-03-01DOI: 10.12983/IJSRK-2016-P0064-0068
Syed Yasir Hussain, Mehjabeen, A. Rafeeq, Mansoor M Ahmed
Gestational diabetes mellitus (GDM) is very common medical condition of pregnancy, associated with maternal and neonatal adverse outcomes. Studies suggested that maternal and neonatal complications of gestational diabetes mellitus can be reduced by diet and life style modification, treatment with oral hypoglycemic agent and insulin. The present study was performed to compare the maternal and neonatal consequences in gestational diabetes mellitus patients, those treated with metformin with those treated with insulin. Retrospective study was performed including 31 gestational diabetes mellitus patients treated with metformin and 31 gestational diabetes mellitus patients treated with insulin. It was found that there was no difference between metformin treated patients and insulin treated patients regarding maternal outcomes (body mass index, pregnancy induced hypertension, preeclampsia, candidiasis etc.). Cesarean deliveries were significantly higher in metformin treated group than in insulin group (p<0.05). Forty eight percent GDM patients treated with metformin group underwent cesarean section. The frequency of full term live birth was higher in insulin group than in metformin group (p<0.001). Fifty five percent patients treated with metformin stay at hospital more than 24 hours. There was no difference between the groups in other neonatal outcomes (preterm live birth, macrosomia, still birth, miscarriage, respiratory distress syndrome etc.). The only incidence of neonatal hypoglycemia was higher in insulin group. The data of present retrospective study suggests that there was no major difference in maternal and neonatal outcomes in metformin and insulin treated GDM patients, both drugs showed good glycemic control in GDM patients which resulted in reduction of maternal and perinatal complications, furthermore insulin was not associated with the higher incidence of cesarean section, post natal stay at hospital and preterm live birth compare with metformin.
{"title":"Metformin and Insulin Therapy in GDM – Comparison of Maternal and Neonatal Complications","authors":"Syed Yasir Hussain, Mehjabeen, A. Rafeeq, Mansoor M Ahmed","doi":"10.12983/IJSRK-2016-P0064-0068","DOIUrl":"https://doi.org/10.12983/IJSRK-2016-P0064-0068","url":null,"abstract":"Gestational diabetes mellitus (GDM) is very common medical condition of pregnancy, associated with maternal and neonatal adverse outcomes. Studies suggested that maternal and neonatal complications of gestational diabetes mellitus can be reduced by diet and life style modification, treatment with oral hypoglycemic agent and insulin. The present study was performed to compare the maternal and neonatal consequences in gestational diabetes mellitus patients, those treated with metformin with those treated with insulin. Retrospective study was performed including 31 gestational diabetes mellitus patients treated with metformin and 31 gestational diabetes mellitus patients treated with insulin. It was found that there was no difference between metformin treated patients and insulin treated patients regarding maternal outcomes (body mass index, pregnancy induced hypertension, preeclampsia, candidiasis etc.). Cesarean deliveries were significantly higher in metformin treated group than in insulin group (p<0.05). Forty eight percent GDM patients treated with metformin group underwent cesarean section. The frequency of full term live birth was higher in insulin group than in metformin group (p<0.001). Fifty five percent patients treated with metformin stay at hospital more than 24 hours. There was no difference between the groups in other neonatal outcomes (preterm live birth, macrosomia, still birth, miscarriage, respiratory distress syndrome etc.). The only incidence of neonatal hypoglycemia was higher in insulin group. The data of present retrospective study suggests that there was no major difference in maternal and neonatal outcomes in metformin and insulin treated GDM patients, both drugs showed good glycemic control in GDM patients which resulted in reduction of maternal and perinatal complications, furthermore insulin was not associated with the higher incidence of cesarean section, post natal stay at hospital and preterm live birth compare with metformin.","PeriodicalId":14310,"journal":{"name":"International Journal of Scientific Research in Knowledge","volume":"32 1","pages":"64-68"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90829575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-03-01DOI: 10.12983/IJSRK-2016-P0056-0063
Vanshika Singh, A. Alam, Apoorva Sharma
Plants are the ultimate source of drugs against many communicable diseases since time immemorial. Multitudinous drugs have been obtained from countless plant species. However, invariably angiosperms were the preferred choice of most of the workers and other plant groups remain somewhat unexplored in this direction. Hence, the aim of the present study was to examine the phytochemicals, antioxidant and antibacterial activity of two such neglected mosses (bryophyta), Hyophila involuta (Hook.) Jaeg. and Entodon plicatus C. Muell. (Bryopsida). In preluded phytochemical analysis cardiac glycosides, flavonoids, saponins, anthroquinone, terpenoids, tannins, phenolic, proteins, fats and fixed oils were observed by using standard tests. It was found that E. plicatus contains more amount of phytochemicals than H. involuta. The antioxidant activity of both the plants was also determined according to standard protocols and appealing results were found. Comparative analysis was done for the activity of Catalase, Peroxidase, Ascorbate peroxidase, Glutathione reductase and Superoxide dismutase and interesting observations were made. Antimicrobial activity of methanolic extracts of both the plants was evaluated against Bacillus subtilis, B. cereus and Escherichia coli by using the Agar well diffusion method. Extract of H. involuta showed a greater inhibitory activity than Entodon plicatus. Bacillus spp. (gram+ve) were found more affected than E. coli (gram-ve).
自古以来，植物就是治疗许多传染病的药物的最终来源。从无数种植物中提取了大量的药物。然而，被子植物始终是大多数工蚁的首选，而其他植物类群在这个方向上仍未被探索。因此，本研究的目的是研究两种被忽视的苔藓植物(苔藓植物)的植物化学成分、抗氧化和抗菌活性。Jaeg。和Entodon plicatus C. Muell。(苔藓植物)。在前体植物化学分析中，采用标准试验法对心脏苷类、黄酮类、皂苷类、蒽醌类、萜类、单宁类、酚类、蛋白质类、脂肪类和固定油类进行了分析。结果表明，虎皮莲的植物化学物质含量高于天竺葵。根据标准方案测定了两种植物的抗氧化活性，并得出了令人满意的结果。对过氧化氢酶、过氧化物酶、抗坏血酸过氧化物酶、谷胱甘肽还原酶和超氧化物歧化酶的活性进行了比较分析，得出了有趣的观察结果。采用琼脂孔扩散法测定了两种植物甲醇提取物对枯草芽孢杆菌、蜡样芽孢杆菌和大肠杆菌的抑菌活性。渐开线花提取物的抑菌活性明显高于皱褶藤提取物。发现芽孢杆菌(g +ve)比大肠杆菌(g -ve)受感染更严重。
{"title":"Evaluation of Phytochemicals, Antioxidant and Antibacterial Activity of Hyophila involuta (Hook.) Jaeg. and Entodon plicatus C.Muell. (Bryophyta) from Rajasthan, India","authors":"Vanshika Singh, A. Alam, Apoorva Sharma","doi":"10.12983/IJSRK-2016-P0056-0063","DOIUrl":"https://doi.org/10.12983/IJSRK-2016-P0056-0063","url":null,"abstract":"Plants are the ultimate source of drugs against many communicable diseases since time immemorial. Multitudinous drugs have been obtained from countless plant species. However, invariably angiosperms were the preferred choice of most of the workers and other plant groups remain somewhat unexplored in this direction. Hence, the aim of the present study was to examine the phytochemicals, antioxidant and antibacterial activity of two such neglected mosses (bryophyta), Hyophila involuta (Hook.) Jaeg. and Entodon plicatus C. Muell. (Bryopsida). In preluded phytochemical analysis cardiac glycosides, flavonoids, saponins, anthroquinone, terpenoids, tannins, phenolic, proteins, fats and fixed oils were observed by using standard tests. It was found that E. plicatus contains more amount of phytochemicals than H. involuta. The antioxidant activity of both the plants was also determined according to standard protocols and appealing results were found. Comparative analysis was done for the activity of Catalase, Peroxidase, Ascorbate peroxidase, Glutathione reductase and Superoxide dismutase and interesting observations were made. Antimicrobial activity of methanolic extracts of both the plants was evaluated against Bacillus subtilis, B. cereus and Escherichia coli by using the Agar well diffusion method. Extract of H. involuta showed a greater inhibitory activity than Entodon plicatus. Bacillus spp. (gram+ve) were found more affected than E. coli (gram-ve).","PeriodicalId":14310,"journal":{"name":"International Journal of Scientific Research in Knowledge","volume":"213 1","pages":"56-63"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73979402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-03-01DOI: 10.12983/IJSRK-2016-P0069-0076
Shailja Dwivedi, A. Alam, G. S. Shekhawat, V. Sharma, J. Kumari
Equilibrium between production and destruction of all the enzymatic and non enzymatic biochemicals of living organisms is required for metabolic efficiency, which can maintain the normal functions (growth, reproduction and development) of such organism at normal or stressed condition. A repetitively high or extremely low production of antioxidant enzyme against meticulous toxicity can cause damage to the cells. In the current attempt activity of enzymatic and nonenzymatic biochemicals of Stevia rebaudiana callus were examined under fluoride induced stress. Exposure of fluoride was applied for 15 days at in vitro thermostatically controlled condition. Calli were sustained upto 3mM concentration of fluoride while at 1M fluoride 61% reduction was observed. Chl a, Chl B and total chlorophyll show a steady decrease while the amount of proline, catalase, ascorbate peroxidase and Superoxide dismutase got elevated at lower concentrations and alleviated at higher concentration. As a result of this biochemical imbalance at each concentration of Fluoride the rate of lipid peroxidation got increased and was highest at 1M concentration.
{"title":"Enzymatic and Non-Enzymatic Behaviour of Stevia rebaudiana (Bertoni) Bertoni Against Fluoride Induced Stress","authors":"Shailja Dwivedi, A. Alam, G. S. Shekhawat, V. Sharma, J. Kumari","doi":"10.12983/IJSRK-2016-P0069-0076","DOIUrl":"https://doi.org/10.12983/IJSRK-2016-P0069-0076","url":null,"abstract":"Equilibrium between production and destruction of all the enzymatic and non enzymatic biochemicals of living organisms is required for metabolic efficiency, which can maintain the normal functions (growth, reproduction and development) of such organism at normal or stressed condition. A repetitively high or extremely low production of antioxidant enzyme against meticulous toxicity can cause damage to the cells. In the current attempt activity of enzymatic and nonenzymatic biochemicals of Stevia rebaudiana callus were examined under fluoride induced stress. Exposure of fluoride was applied for 15 days at in vitro thermostatically controlled condition. Calli were sustained upto 3mM concentration of fluoride while at 1M fluoride 61% reduction was observed. Chl a, Chl B and total chlorophyll show a steady decrease while the amount of proline, catalase, ascorbate peroxidase and Superoxide dismutase got elevated at lower concentrations and alleviated at higher concentration. As a result of this biochemical imbalance at each concentration of Fluoride the rate of lipid peroxidation got increased and was highest at 1M concentration.","PeriodicalId":14310,"journal":{"name":"International Journal of Scientific Research in Knowledge","volume":"65 1","pages":"69-76"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73906871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-02-01DOI: 10.12983/IJSRK-2016-P0028-0032
A. Rafeeq, Rahila Najam, Syed Yasir Hussain
Acetylsalicylic acid (Aspirin) belongs to nonsteroidal anti-inflammatory drugs (NSAIDs). Numerous studies have proven that aspirin reduces the signs and symptoms of inflammation and exhibited a broad range of pharmacological activities, including analgesic, antipyretic and antiplatelet properties. Previous studies suggested that beside the pharmacological activities aspirin was also associated with the side effects and toxicity of various doses and in various formulations. The present study is performed to explore the effects of aspirin in various doses (75mg (EC), 100mg, 150 (EC)mg and 300mg) in different preparation (enteric coated (EC), non-enteric coated) on liver enzymes (Serum glutamic oxaloacetate transaminase (SGOT) and Serum glutamic pyruvic transaminase (SGPT)) followed by daily administration for 10 days and for 30 days. We found that the SGOT level was increased by all doses of aspirin after 30 days of treatment, this effect was most significant at 75mg (EC) and 100mg dose, whereas at 150mg (EC) and 300mg was not very significant. The level of SGPT was decreased by all doses regardless of duration of treatment, only 75mg (EC) dose increased its level after 30 days of treatment, suggesting 75mg (EC) aspirin could be hepatotoxic due to lessen of anti-oxidant effects, furthermore suggests that patients with hepatic insufficiency should not receive 75mg (EC) dose of aspirin.
{"title":"Aspirin Associated Liver Toxicity – The Optimal Dose of Aspirin in Liver Insufficiency","authors":"A. Rafeeq, Rahila Najam, Syed Yasir Hussain","doi":"10.12983/IJSRK-2016-P0028-0032","DOIUrl":"https://doi.org/10.12983/IJSRK-2016-P0028-0032","url":null,"abstract":"Acetylsalicylic acid (Aspirin) belongs to nonsteroidal anti-inflammatory drugs (NSAIDs). Numerous studies have proven that aspirin reduces the signs and symptoms of inflammation and exhibited a broad range of pharmacological activities, including analgesic, antipyretic and antiplatelet properties. Previous studies suggested that beside the pharmacological activities aspirin was also associated with the side effects and toxicity of various doses and in various formulations. The present study is performed to explore the effects of aspirin in various doses (75mg (EC), 100mg, 150 (EC)mg and 300mg) in different preparation (enteric coated (EC), non-enteric coated) on liver enzymes (Serum glutamic oxaloacetate transaminase (SGOT) and Serum glutamic pyruvic transaminase (SGPT)) followed by daily administration for 10 days and for 30 days. We found that the SGOT level was increased by all doses of aspirin after 30 days of treatment, this effect was most significant at 75mg (EC) and 100mg dose, whereas at 150mg (EC) and 300mg was not very significant. The level of SGPT was decreased by all doses regardless of duration of treatment, only 75mg (EC) dose increased its level after 30 days of treatment, suggesting 75mg (EC) aspirin could be hepatotoxic due to lessen of anti-oxidant effects, furthermore suggests that patients with hepatic insufficiency should not receive 75mg (EC) dose of aspirin.","PeriodicalId":14310,"journal":{"name":"International Journal of Scientific Research in Knowledge","volume":"5 1","pages":"28-32"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87270535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-02-01DOI: 10.12983/IJSRK-2016-P0040-0055
H. Zamanian, Farid Javidpour
Skid-steered vehicles are regularly considered for outdoor activities due to their structural robustness and extraordinary maneuverability. Dynamic model of ground vehicles should predict a faithful motion in unknown environments and ability to design a proper controller. The purpose of this paper is to develop a nonlinear model for a 4-wheel skid-steering mobile robot considering dynamic model of tires with all slides. Unlike previous friction models which are considering only frictional forces without tire's slips, the proposed model consists of longitudinal and lateral tires' slips and will be used to predict a real robot's (P3-AT) motion in some specified situations such as moving straight on horizontal and ascent planes and moving on a curve on a horizontal plane. For validation purposes, obtained results will be compared to similar simulations on an Adams/View model. This comparison shows the accuracy of the model. Finally, advantage and disadvantage of the proposed model will be discussed.
{"title":"Dynamic Modeling and Simulation of 4-Wheel Skid-Steering Mobile Robot with Considering Tires Longitudinal and Lateral Slips","authors":"H. Zamanian, Farid Javidpour","doi":"10.12983/IJSRK-2016-P0040-0055","DOIUrl":"https://doi.org/10.12983/IJSRK-2016-P0040-0055","url":null,"abstract":"Skid-steered vehicles are regularly considered for outdoor activities due to their structural robustness and extraordinary maneuverability. Dynamic model of ground vehicles should predict a faithful motion in unknown environments and ability to design a proper controller. The purpose of this paper is to develop a nonlinear model for a 4-wheel skid-steering mobile robot considering dynamic model of tires with all slides. Unlike previous friction models which are considering only frictional forces without tire's slips, the proposed model consists of longitudinal and lateral tires' slips and will be used to predict a real robot's (P3-AT) motion in some specified situations such as moving straight on horizontal and ascent planes and moving on a curve on a horizontal plane. For validation purposes, obtained results will be compared to similar simulations on an Adams/View model. This comparison shows the accuracy of the model. Finally, advantage and disadvantage of the proposed model will be discussed.","PeriodicalId":14310,"journal":{"name":"International Journal of Scientific Research in Knowledge","volume":"73 1","pages":"40-55"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76452593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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