首页 > 最新文献

International journal of pediatric otorhinolaryngology最新文献

英文 中文
Long-term safety and audiological results with the Bone Conduction Implant 601 in children younger than 12 years old 骨传导植入601用于12岁以下儿童的长期安全性和听力学结果
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-20 DOI: 10.1016/j.ijporl.2025.112652
Yuan Wang , Jikai Zhu , Danni Wang , Shouqin Zhao

Objective

To evaluate the long-term safety, efficacy, and satisfaction of Bonebridge implantation in children under 12 years.

Methods

This retrospective study followed 34 patients (aged 5.4–11.8 years) who underwent Bonebridge implantation between 2016 and 2020, with a median follow-up of 55 months. Audiological outcomes, including pure-tone audiometry (PTA), speech reception thresholds (SRTs), speech discrimination scores (SDSs), and sound field hearing thresholds (SFHTs) were assessed. Adverse events and patient-reported satisfaction (HDSS) were recorded.

Results

Bonebridge significantly improved speech perception (SRT: −6.20 dB in unilateral; −0.18 dB in bilateral) and SFHT (mean improvement: 20.80 dB unilateral; 29.07 dB bilateral). SDS for monosyllables, disyllables, and sentences showed substantial gains in aided conditions. Adverse events were mild to moderate, except for one serious device failure resolved with revision surgery. Sound localization accuracy decreased in patients with bilateral hearing loss who used a unilateral Bonebridge due to unilateral auditory stimulation. Patient satisfaction was high, with bilateral hearing loss reporting longer daily usage.

Conclusion

Bonebridge is a safe and effective intervention for young children under 12 years with conductive hearing loss, enhancing auditory access and quality of life.
目的评价12岁以下儿童骨桥植入术的长期安全性、有效性和满意度。方法回顾性研究2016 - 2020年间34例骨桥植入术患者(年龄5.4-11.8岁),中位随访55个月。听力学指标包括纯音测听(PTA)、语音接收阈值(srt)、语音辨别评分(SDSs)和声场听力阈值(SFHTs)。记录不良事件和患者报告满意度(HDSS)。结果骨桥显著改善了语音感知(单侧SRT:−6.20 dB;双侧- 0.18 dB)和SFHT(平均改善:单侧20.80 dB;双侧29.07 dB)。单音节、双音节和句子的SDS在辅助条件下显示出实质性的进步。不良事件为轻度至中度,除了一例严重的器械故障通过翻修手术解决。由于单侧听觉刺激,使用单侧骨桥的双侧听力损失患者声音定位准确性下降。患者满意度高,双侧听力损失患者报告每日使用时间较长。结论骨桥治疗12岁以下传导性听力损失是一种安全有效的干预方法,可改善儿童的听觉通路和生活质量。
{"title":"Long-term safety and audiological results with the Bone Conduction Implant 601 in children younger than 12 years old","authors":"Yuan Wang ,&nbsp;Jikai Zhu ,&nbsp;Danni Wang ,&nbsp;Shouqin Zhao","doi":"10.1016/j.ijporl.2025.112652","DOIUrl":"10.1016/j.ijporl.2025.112652","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the long-term safety, efficacy, and satisfaction of Bonebridge implantation in children under 12 years.</div></div><div><h3>Methods</h3><div>This retrospective study followed 34 patients (aged 5.4–11.8 years) who underwent Bonebridge implantation between 2016 and 2020, with a median follow-up of 55 months. Audiological outcomes, including pure-tone audiometry (PTA), speech reception thresholds (SRTs), speech discrimination scores (SDSs), and sound field hearing thresholds (SFHTs) were assessed. Adverse events and patient-reported satisfaction (HDSS) were recorded.</div></div><div><h3>Results</h3><div>Bonebridge significantly improved speech perception (SRT: −6.20 dB in unilateral; −0.18 dB in bilateral) and SFHT (mean improvement: 20.80 dB unilateral; 29.07 dB bilateral). SDS for monosyllables, disyllables, and sentences showed substantial gains in aided conditions. Adverse events were mild to moderate, except for one serious device failure resolved with revision surgery. Sound localization accuracy decreased in patients with bilateral hearing loss who used a unilateral Bonebridge due to unilateral auditory stimulation. Patient satisfaction was high, with bilateral hearing loss reporting longer daily usage.</div></div><div><h3>Conclusion</h3><div>Bonebridge is a safe and effective intervention for young children under 12 years with conductive hearing loss, enhancing auditory access and quality of life.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"199 ","pages":"Article 112652"},"PeriodicalIF":1.3,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145569815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Objective evaluation of hearing aids fitting efficacy in pediatric populations using cortical auditory evoked potentials 目的利用皮质听觉诱发电位评价儿童助听器配戴效果。
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-20 DOI: 10.1016/j.ijporl.2025.112651
Qianqian Guo , Chao Meng , Jing Lyu , Yuling Li , Xueqing Chen

Objective

This study aimed to investigate the relationships between cortical auditory evoked potentials (CAEPs), behavioral aided hearing thresholds, and functional auditory performance to validate CAEPs as an objective tool for assessing hearing aids fitting and to develop an integrated test battery for children with hearing loss.

Methods

Thirty children (aged 24–60 months) with bilateral sensorineural hearing loss were participated in this study. CAEPs were recorded in sound field using the HEARLab™ system in response to three speech stimuli (/m/,/g/,/t/) presented at 55, 65, and 75 dB SPL. Participants were categorized into Group A (CAEPs present for all stimuli at 55 dB SPL, n = 12) and Group B (absent waveforms at 55 dB SPL, n = 18). Aided sound-field thresholds were behaviorally assessed, and functional auditory performance was evaluated using the validated Mandarin version of the Parents' Evaluation of Aural/Oral Performance of Children (PEACH) scale.

Results

Group A demonstrated aided thresholds within the speech banana across all tested frequencies, whereas Group B exhibited significantly higher thresholds. CAEPs detectability was strongly dependent on sensation level (SL), with waveforms consistently detected above 10 dB SL. P1 latency decreased significantly with increasing SL (β = −0.513 ms/dB, p < 0.001), while P1 amplitude increased (β = 2.827 μV/dB, p < 0.001). A strong positive correlation was observed between CAEP scores and PEACH questionnaire results (r = 0.884, p < 0.001).

Conclusion

CAEPs provide an objective and frequency-specific neurophysiological method for verifying HAs fitting outcomes in children who are unable to cooperate with conventional subjective testing.
目的:本研究旨在探讨皮质听觉诱发电位(CAEPs)、行为辅助听力阈值和功能性听觉表现之间的关系,以验证CAEPs作为评估助听器适合性的客观工具,并开发一种用于听力损失儿童的综合测试电池。方法:选取30例双侧感音神经性听力损失患儿(年龄24-60月龄)为研究对象。使用HEARLab™系统在声场中记录caep,以响应55、65和75 dB SPL的三种语音刺激(/m/、/g/、/t/)。参与者被分为A组(55 dB SPL下所有刺激都有caep, n = 12)和B组(55 dB SPL下没有波形,n = 18)。对辅助声场阈值进行行为评估,并使用经验证的普通话版《父母对儿童听觉/口头表现的评价》(PEACH)量表对功能性听觉表现进行评估。结果:A组在所有测试频率中表现出语音香蕉内的辅助阈值,而B组表现出明显更高的阈值。CAEPs的可检测性强烈依赖于感觉水平(SL),波形在10 dB SL以上均可检测到。P1潜伏期随着SL的增加而显著降低(β = -0.513 ms/dB), p结论:CAEPs为无法配合常规主观测试的儿童验证HAs拟合结果提供了客观和频率特异性的神经生理学方法。
{"title":"Objective evaluation of hearing aids fitting efficacy in pediatric populations using cortical auditory evoked potentials","authors":"Qianqian Guo ,&nbsp;Chao Meng ,&nbsp;Jing Lyu ,&nbsp;Yuling Li ,&nbsp;Xueqing Chen","doi":"10.1016/j.ijporl.2025.112651","DOIUrl":"10.1016/j.ijporl.2025.112651","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the relationships between cortical auditory evoked potentials (CAEPs), behavioral aided hearing thresholds, and functional auditory performance to validate CAEPs as an objective tool for assessing hearing aids fitting and to develop an integrated test battery for children with hearing loss.</div></div><div><h3>Methods</h3><div>Thirty children (aged 24–60 months) with bilateral sensorineural hearing loss were participated in this study. CAEPs were recorded in sound field using the HEARLab™ system in response to three speech stimuli (/m/,/g/,/t/) presented at 55, 65, and 75 dB SPL. Participants were categorized into Group A (CAEPs present for all stimuli at 55 dB SPL, n = 12) and Group B (absent waveforms at 55 dB SPL, n = 18). Aided sound-field thresholds were behaviorally assessed, and functional auditory performance was evaluated using the validated Mandarin version of the Parents' Evaluation of Aural/Oral Performance of Children (PEACH) scale.</div></div><div><h3>Results</h3><div>Group A demonstrated aided thresholds within the speech banana across all tested frequencies, whereas Group B exhibited significantly higher thresholds. CAEPs detectability was strongly dependent on sensation level (SL), with waveforms consistently detected above 10 dB SL. P1 latency decreased significantly with increasing SL (β = −0.513 ms/dB, <em>p</em> &lt; 0.001), while P1 amplitude increased (β = 2.827 μV/dB, <em>p</em> &lt; 0.001). A strong positive correlation was observed between CAEP scores and PEACH questionnaire results (r = 0.884, <em>p</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>CAEPs provide an objective and frequency-specific neurophysiological method for verifying HAs fitting outcomes in children who are unable to cooperate with conventional subjective testing.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"200 ","pages":"Article 112651"},"PeriodicalIF":1.3,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145654336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosing tracheostomy allergy: Improving airway outcomes in pediatric patients with an active larynx 诊断气管造口术过敏:改善儿童喉活动患者的气道预后
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-19 DOI: 10.1016/j.ijporl.2025.112643
Nicole Kloosterman , Alessandro de Alarcon , Eric Schauberger , Lyndy J. Wilcox

Introduction

Children with an active larynx have a decreased success rate of airway reconstruction and, therefore, require evaluation and management of laryngeal inflammation and associated factors prior to undertaking reconstructive surgery and decannulation. Allergy to the tracheostomy tube is an additional potential cause of active larynx.

Study design

Retrospective case series.

Methods

Patients ages 0–18 years with a tracheostomy who were previously diagnosed with active larynx or peristomal inflammation and underwent patch testing to tracheostomy components at a single quaternary academic children's hospital from January 1, 2014 to May 1, 2018 were identified. Pre-testing, testing, and post-testing results and clinical courses were documented.

Results

Eight patients who met criteria and underwent patch testing for tracheostomy components were identified. Four (50 %) of the patients had positive allergy tests - three for metal components and one to silicone. These four patients subsequently underwent tracheostomy changes. All four patients had improvement in active larynx with proceeding with successful airway reconstruction and/or decannulation.

Conclusions

Tracheostomy allergy should be considered in children with idiopathic active larynx or peristomal inflammation that is not responding to typical measures. Allergy testing is low-risk and a relatively simple intervention which has the potential to demonstrate an intervenable cause of inflammation. Airway inflammation is often multifactorial and future studies require additional investigation regarding the pathophysiology and improvement of the management of the active larynx.
喉部活动的儿童气道重建成功率较低,因此,在进行重建手术和脱管之前,需要评估和处理喉部炎症和相关因素。对气管造口管过敏是另一个潜在的导致喉活动的原因。研究设计:回顾性病例系列。方法选取2014年1月1日至2018年5月1日在某第四专科儿童医院接受气管造口术的0-18岁患者,既往诊断为喉部活动或口周炎症,并对气管造口术成分进行了贴片试验。记录了测试前、测试和测试后的结果和临床过程。结果8例患者均符合标准,均行气管切开术成分贴片试验。4名(50%)患者过敏测试呈阳性,其中3名对金属成分过敏,1名对硅胶过敏。这4例患者随后接受了气管造口术改变。通过成功的气道重建和/或去管术,所有4例患者的活动喉部均有改善。结论对于特发性喉活动或经常规治疗无效的胃黏膜炎患儿,应考虑气管造口术过敏。过敏测试是一种低风险和相对简单的干预,有可能证明炎症的可干预原因。气道炎症通常是多因素的,未来的研究需要对活动喉部的病理生理学和改善管理进行进一步的调查。
{"title":"Diagnosing tracheostomy allergy: Improving airway outcomes in pediatric patients with an active larynx","authors":"Nicole Kloosterman ,&nbsp;Alessandro de Alarcon ,&nbsp;Eric Schauberger ,&nbsp;Lyndy J. Wilcox","doi":"10.1016/j.ijporl.2025.112643","DOIUrl":"10.1016/j.ijporl.2025.112643","url":null,"abstract":"<div><h3>Introduction</h3><div>Children with an active larynx have a decreased success rate of airway reconstruction and, therefore, require evaluation and management of laryngeal inflammation and associated factors prior to undertaking reconstructive surgery and decannulation. Allergy to the tracheostomy tube is an additional potential cause of active larynx.</div></div><div><h3>Study design</h3><div>Retrospective case series.</div></div><div><h3>Methods</h3><div>Patients ages 0–18 years with a tracheostomy who were previously diagnosed with active larynx or peristomal inflammation and underwent patch testing to tracheostomy components at a single quaternary academic children's hospital from January 1, 2014 to May 1, 2018 were identified. Pre-testing, testing, and post-testing results and clinical courses were documented.</div></div><div><h3>Results</h3><div>Eight patients who met criteria and underwent patch testing for tracheostomy components were identified. Four (50 %) of the patients had positive allergy tests - three for metal components and one to silicone. These four patients subsequently underwent tracheostomy changes. All four patients had improvement in active larynx with proceeding with successful airway reconstruction and/or decannulation.</div></div><div><h3>Conclusions</h3><div>Tracheostomy allergy should be considered in children with idiopathic active larynx or peristomal inflammation that is not responding to typical measures. Allergy testing is low-risk and a relatively simple intervention which has the potential to demonstrate an intervenable cause of inflammation. Airway inflammation is often multifactorial and future studies require additional investigation regarding the pathophysiology and improvement of the management of the active larynx.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"199 ","pages":"Article 112643"},"PeriodicalIF":1.3,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145569818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of a tracheostomy-safe bronchoscopy protocol on pediatric tracheostomy outcomes 气管切开术安全支气管镜检查方案对儿童气管切开术结果的影响
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-19 DOI: 10.1016/j.ijporl.2025.112648
Michelle Florentine , Alyssa M. Civantos , Kimberly Luu, Lia Jacobson

Objective

A Tracheostomy-Safe Bronchoscopy Protocol was developed at our institution in 2019, which aimed to identify and treat upper airway pathologies early and establish emergency airway plans. The objective of this study was to assess the impact of this protocol on tracheostomy-related complications and outcomes.

Methods

A retrospective chart review of pediatric patients who underwent tracheostomy between 2015 and 2022 at our institution's two tertiary children's hospitals was conducted. Demographic, operative, and clinical data were collected. Univariate and multivariable analyses were used to assess impact on outcomes, including need for event-initiated intervention, tracheostomy-related complications in the year after surgery, and time to decannulation.

Results

A total of 106 patients were included, of which 62 % underwent tracheostomy after implementation of the protocol. The average age at tracheostomy was 42 months. Of the 42 patients who underwent their first rigid bronchoscopy within 8 weeks, 64 % had at least one intervention, most commonly granulation tissue removal (40 %). Average time to first rigid bronchoscopy was significantly decreased after the protocol compared to before (mean 2.76 vs. 6.61 months, p = 0.01). The post-implementation cohort had significant decreases in the number of first bronchoscopies being adverse-event-induced (36.36 % vs 14.29 %, p = 0.02), in respiratory-related admissions in the year after surgery (mean 0.35 vs 1.61, p = 0.002), and in the average time to decannulation (46.0 months vs 10.45 months, p = 0.012) compared to the pre-implementation cohort.

Conclusion

Pediatric patients with tracheostomies are at risk of developing upper airway pathologies. Implementation of a Tracheostomy-Safe Bronchoscopy Protocol may allow for early identification of potential complications.
目的2019年,我院制定了气管造口安全支气管镜检查方案,旨在早期发现和治疗上气道病变,制定气道应急预案。本研究的目的是评估该方案对气管切开术相关并发症和结果的影响。方法对我院两所三级儿童医院2015 - 2022年气管切开术患儿进行回顾性统计分析。收集了人口学、手术和临床资料。使用单变量和多变量分析来评估对结果的影响,包括事件启动干预的需要、手术后一年气管造口术相关并发症和脱管时间。结果共纳入106例患者,其中62%的患者在实施该方案后行气管切开术。气管切开术的平均年龄为42个月。在8周内接受第一次刚性支气管镜检查的42例患者中,64%至少进行了一次干预,最常见的是肉芽组织切除(40%)。与治疗前相比,治疗方案后进行首次刚性支气管镜检查的平均时间显著缩短(平均2.76个月vs. 6.61个月,p = 0.01)。与实施前队列相比,实施后队列在不良事件诱发的首次支气管镜检查次数(36.36% vs 14.29%, p = 0.02)、术后一年呼吸相关入院次数(平均0.35 vs 1.61, p = 0.002)和平均去管时间(46.0个月vs 10.45个月,p = 0.012)均显著减少。结论小儿气管切开术患者存在发生上气道病变的风险。气管切开术安全支气管镜检查方案的实施可能允许早期识别潜在的并发症。
{"title":"The impact of a tracheostomy-safe bronchoscopy protocol on pediatric tracheostomy outcomes","authors":"Michelle Florentine ,&nbsp;Alyssa M. Civantos ,&nbsp;Kimberly Luu,&nbsp;Lia Jacobson","doi":"10.1016/j.ijporl.2025.112648","DOIUrl":"10.1016/j.ijporl.2025.112648","url":null,"abstract":"<div><h3>Objective</h3><div>A Tracheostomy-Safe Bronchoscopy Protocol was developed at our institution in 2019, which aimed to identify and treat upper airway pathologies early and establish emergency airway plans. The objective of this study was to assess the impact of this protocol on tracheostomy-related complications and outcomes.</div></div><div><h3>Methods</h3><div>A retrospective chart review of pediatric patients who underwent tracheostomy between 2015 and 2022 at our institution's two tertiary children's hospitals was conducted. Demographic, operative, and clinical data were collected. Univariate and multivariable analyses were used to assess impact on outcomes, including need for event-initiated intervention, tracheostomy-related complications in the year after surgery, and time to decannulation.</div></div><div><h3>Results</h3><div>A total of 106 patients were included, of which 62 % underwent tracheostomy after implementation of the protocol. The average age at tracheostomy was 42 months. Of the 42 patients who underwent their first rigid bronchoscopy within 8 weeks, 64 % had at least one intervention, most commonly granulation tissue removal (40 %). Average time to first rigid bronchoscopy was significantly decreased after the protocol compared to before (mean 2.76 vs. 6.61 months, p = 0.01). The post-implementation cohort had significant decreases in the number of first bronchoscopies being adverse-event-induced (36.36 % vs 14.29 %, p = 0.02), in respiratory-related admissions in the year after surgery (mean 0.35 vs 1.61, p = 0.002), and in the average time to decannulation (46.0 months vs 10.45 months, p = 0.012) compared to the pre-implementation cohort.</div></div><div><h3>Conclusion</h3><div>Pediatric patients with tracheostomies are at risk of developing upper airway pathologies. Implementation of a Tracheostomy-Safe Bronchoscopy Protocol may allow for early identification of potential complications.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"199 ","pages":"Article 112648"},"PeriodicalIF":1.3,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145569816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of parent-child play-based vocal training in school-age children with vocal fold nodules 亲子游戏式发声训练在学龄期声带小结儿童中的应用。
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-19 DOI: 10.1016/j.ijporl.2025.112647
Xueqing Song , Yinli Duo , Shurong Li , Xiaohong Li , Li Hou , Yao Geng

Objective

To investigate the effects of parent-child interactive medical games combined with voice training on the vocal function and quality of life of school-aged children with vocal nodules, and to identify effective methods for improving the vocal function of children with vocal nodules.

Methods

Eighty school-aged children with vocal nodules were randomly assigned to a control group (n = 40) and an intervention group (n = 40). The control group received conventional voice training, while the intervention group underwent parent-child interactive medical games combined with voice training. After an 8-week intervention period, objective voice acoustic parameter scores, pediatric voice disorder index scores, and voice-related quality of life scores were compared between groups.

Results

Forty subjects in each group completed the study. After 8 weeks of intervention, the intervention group demonstrated significantly improved scores for Jitter, Shimmer, and F0 compared to the control group. Additionally, the intervention group exhibited lower scores on the Pediatric Voice Disorder Index and lower scores on voice-related quality of life measures than the control group (all P < 0.01).

Conclusion

Combining parent-child interactive medical games with voice training can improve objective acoustic parameters of the voice in school-aged children with vocal nodules, reduce voice disorders in this population, enhance their quality of life, and promote vocal fold recovery.
目的:探讨亲子互动医疗游戏结合发声训练对学龄期声带小结儿童发声功能及生活质量的影响,寻找改善声带小结儿童发声功能的有效方法。方法:80例学龄期声带小结患儿随机分为对照组(n = 40)和干预组(n = 40)。对照组采用常规语音训练,干预组采用亲子互动医疗游戏结合语音训练。干预8周后,比较两组儿童客观嗓音声学参数评分、儿童语音障碍指数评分、语音相关生活质量评分。结果:每组40名受试者完成研究。干预8周后,与对照组相比,干预组在Jitter, Shimmer和F0方面的得分显著提高。干预组儿童语音障碍指数得分和语音相关生活质量指标得分均低于对照组(P)结论:亲子互动医疗游戏与语音训练相结合,可改善学龄期声带小结儿童语音客观声学参数,减少该人群的语音障碍,提高其生活质量,促进声带恢复。
{"title":"Application of parent-child play-based vocal training in school-age children with vocal fold nodules","authors":"Xueqing Song ,&nbsp;Yinli Duo ,&nbsp;Shurong Li ,&nbsp;Xiaohong Li ,&nbsp;Li Hou ,&nbsp;Yao Geng","doi":"10.1016/j.ijporl.2025.112647","DOIUrl":"10.1016/j.ijporl.2025.112647","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the effects of parent-child interactive medical games combined with voice training on the vocal function and quality of life of school-aged children with vocal nodules, and to identify effective methods for improving the vocal function of children with vocal nodules.</div></div><div><h3>Methods</h3><div>Eighty school-aged children with vocal nodules were randomly assigned to a control group (<em>n</em> = 40) and an intervention group (<em>n</em> = 40). The control group received conventional voice training, while the intervention group underwent parent-child interactive medical games combined with voice training. After an 8-week intervention period, objective voice acoustic parameter scores, pediatric voice disorder index scores, and voice-related quality of life scores were compared between groups.</div></div><div><h3>Results</h3><div>Forty subjects in each group completed the study. After 8 weeks of intervention, the intervention group demonstrated significantly improved scores for Jitter, Shimmer, and F0 compared to the control group. Additionally, the intervention group exhibited lower scores on the Pediatric Voice Disorder Index and lower scores on voice-related quality of life measures than the control group (all <em>P</em> &lt; 0.01).</div></div><div><h3>Conclusion</h3><div>Combining parent-child interactive medical games with voice training can improve objective acoustic parameters of the voice in school-aged children with vocal nodules, reduce voice disorders in this population, enhance their quality of life, and promote vocal fold recovery.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"199 ","pages":"Article 112647"},"PeriodicalIF":1.3,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145563799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patients with allergic rhinitis are more likely to need a secondary adenoidectomy after 6 months 过敏性鼻炎患者在6个月后更有可能需要二次腺样体切除术。
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-11 DOI: 10.1016/j.ijporl.2025.112646
Sofia Piperno , Truman Archer , Sawyer Archer , Elizabeth McCarthy , Delaney E.S. Clark , Brian P. Quinlan , Harold Pine

Background

Adenoidectomy, without concomitant procedures like tonsillectomy, is the third most common ambulatory pediatric operation. Allergic rhinitis is a common comorbidity that is known to cause adenoid hypertrophy. With time and progression, adenoid hypertrophy can become symptomatic and necessitate removal. Our aim is to assess how patients diagnosed with allergic rhinitis affect the need for a secondary adenoidectomy over time.

Methods

We queried the TriNetX database and produced the statistical analysis for this project. The control group consisted of patients who have not been diagnosed with allergic rhinitis and have undergone a primary adenoidectomy. Cohorts were balanced using native TriNetX propensity matching before analysis. Outcomes measured included the presence of secondary adenoidectomy after 0–0.5, 0.5–1, 1–2, 2–3, 3–4, 4–5, 5–7, and 7+ years of primary adenoidectomy.

Results

65,106 patients were assessed with a mean average age of 6.36 ± 7.82 and 6.34 ± 7.71 years between the control and experimental group. There was no difference in secondary adenoidectomy occurrences between the two groups between 1 day and 0.5 years after primary adenoidectomy (p = 0.896, RR 1.632 (0.922,2.888)). There was a difference between 0.5 and 1 year (p < 0.0001), 1–2 years (p < 0.0001), 2–3 years (p < 0.0001), 3–4 years (p = 0.001), 4–5 years (p = 0.001), 5–7 years (p = 0.0002), and more than 7 years (p = 0.0023).

Conclusions

After 0.5 years of primary adenoidectomy surgery, patients diagnosed with allergic rhinitis are more likely to need a secondary adenoidectomy compared to their counterparts not diagnosed with allergic rhinitis.
背景:腺样体切除术是第三种最常见的儿科门诊手术,不伴有扁桃体切除术。过敏性鼻炎是一种常见的共病,已知可引起腺样体肥大。随着时间的推移和进展,腺样体肥大可能成为症状,需要切除。我们的目的是评估诊断为过敏性鼻炎的患者如何随着时间的推移影响二次腺样体切除术的需要。方法:查询TriNetX数据库,对该项目进行统计分析。对照组由未被诊断为过敏性鼻炎且接受过原发性腺样体切除术的患者组成。在分析之前,使用原生TriNetX倾向匹配来平衡队列。测量的结果包括原发性腺样体切除术后0-0.5、0.5-1、1-2、2-3、3-4、4-5、5-7和7年以上的继发腺样体切除术。结果:共纳入65,106例患者,对照组和实验组的平均年龄分别为6.36±7.82岁和6.34±7.71岁。两组患者在原发性腺样体切除术后1天和0.5年内继发腺样体切除术发生率无差异(p = 0.896, RR 1.632(0.922,2.888))。结论:在原发腺样体切除手术0.5年后,诊断为变应性鼻炎的患者比未诊断为变应性鼻炎的患者更有可能需要二次腺样体切除术。
{"title":"Patients with allergic rhinitis are more likely to need a secondary adenoidectomy after 6 months","authors":"Sofia Piperno ,&nbsp;Truman Archer ,&nbsp;Sawyer Archer ,&nbsp;Elizabeth McCarthy ,&nbsp;Delaney E.S. Clark ,&nbsp;Brian P. Quinlan ,&nbsp;Harold Pine","doi":"10.1016/j.ijporl.2025.112646","DOIUrl":"10.1016/j.ijporl.2025.112646","url":null,"abstract":"<div><h3>Background</h3><div>Adenoidectomy, without concomitant procedures like tonsillectomy, is the third most common ambulatory pediatric operation. Allergic rhinitis is a common comorbidity that is known to cause adenoid hypertrophy. With time and progression, adenoid hypertrophy can become symptomatic and necessitate removal. Our aim is to assess how patients diagnosed with allergic rhinitis affect the need for a secondary adenoidectomy over time.</div></div><div><h3>Methods</h3><div>We queried the TriNetX database and produced the statistical analysis for this project. The control group consisted of patients who have not been diagnosed with allergic rhinitis and have undergone a primary adenoidectomy. Cohorts were balanced using native TriNetX propensity matching before analysis. Outcomes measured included the presence of secondary adenoidectomy after 0–0.5, 0.5–1, 1–2, 2–3, 3–4, 4–5, 5–7, and 7+ years of primary adenoidectomy.</div></div><div><h3>Results</h3><div>65,106 patients were assessed with a mean average age of 6.36 ± 7.82 and 6.34 ± 7.71 years between the control and experimental group. There was no difference in secondary adenoidectomy occurrences between the two groups between 1 day and 0.5 years after primary adenoidectomy (p = 0.896, RR 1.632 (0.922,2.888)). There was a difference between 0.5 and 1 year (p &lt; 0.0001), 1–2 years (p &lt; 0.0001), 2–3 years (p &lt; 0.0001), 3–4 years (p = 0.001), 4–5 years (p = 0.001), 5–7 years (p = 0.0002), and more than 7 years (p = 0.0023).</div></div><div><h3>Conclusions</h3><div>After 0.5 years of primary adenoidectomy surgery, patients diagnosed with allergic rhinitis are more likely to need a secondary adenoidectomy compared to their counterparts not diagnosed with allergic rhinitis.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"199 ","pages":"Article 112646"},"PeriodicalIF":1.3,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145512465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors influencing likelihood of inpatient frenotomy in newborns with ankyloglossia 影响新生儿强直性咬合住院截骨可能性的因素。
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-11 DOI: 10.1016/j.ijporl.2025.112644
Jonathan M. Carnino , Sanjeev Rampam , Lindsay R. Salvati , Yash V. Shroff , Dean G. Kennedy , Jessica R. Levi

Objective

This study investigates national trends in inpatient frenotomy for newborns with ankyloglossia, focusing on the association between demographic, socioeconomic, and regional factors and the likelihood of undergoing the procedure.

Methods

Data from the 2016 Kid Inpatient Database (KID) were analyzed to identify hospitalized newborns diagnosed with ankyloglossia. Frenotomy procedures were identified using ICD-10 procedure codes. Chi-square tests were used to evaluate unadjusted associations between categorical variables and frenotomy utilization. Variables significant in univariate analysis were included in a multivariable logistic regression model to calculate adjusted odds ratios (OR) with 95 % confidence intervals (CI).

Results

Among 47,663 newborns with ankyloglossia, 34.8% underwent inpatient frenotomy. Factors independently associated with frenotomy included sex, race, hospital region, and household income. Female newborns had higher odds of frenotomy (OR 1.54, 95 % CI 1.47–1.61), whereas non-White racial groups had lower odds than White newborns. The Midwest had the highest likelihood of frenotomy (OR 3.08, 95 % CI 2.93–3.23), and newborns from the highest income quartile had reduced odds (OR 0.86, 95 % CI 0.80–0.92).

Conclusions

Significant disparities in inpatient frenotomy utilization exist based on demographic, socioeconomic, and regional factors. These findings underscore the need for standardized diagnostic criteria and equitable access to both surgical and non-surgical treatments. Future research should address the impact of these disparities on patient outcomes and explore targeted interventions to reduce variability in care.

Level of evidence

3.
目的:本研究调查全国新生儿强直性咬合住院截骨的趋势,重点研究人口、社会经济和地区因素与接受手术可能性之间的关系。方法:分析2016年儿童住院数据库(Kid)的数据,以识别诊断为强直性咬合的住院新生儿。使用ICD-10程序代码确定截骨手术。卡方检验用于评估分类变量与截骨术使用之间未经调整的相关性。将单因素分析中显著的变量纳入多因素logistic回归模型,以95%置信区间(CI)计算校正优势比(OR)。结果:47,663例新生儿强直性咬合中,34.8%的患者接受了住院截骨术。与截骨术相关的独立因素包括性别、种族、医院区域和家庭收入。女性新生儿接受截骨手术的几率较高(OR 1.54, 95% CI 1.47-1.61),而非白人新生儿的几率低于白人新生儿。中西部地区进行截骨手术的可能性最高(OR 3.08, 95% CI 2.93-3.23),收入最高的四分位数新生儿的可能性较低(OR 0.86, 95% CI 0.80-0.92)。结论:不同人口、社会经济和地区因素对住院患者截骨术使用率的影响存在显著差异。这些发现强调了标准化诊断标准和公平获得手术和非手术治疗的必要性。未来的研究应解决这些差异对患者结果的影响,并探索有针对性的干预措施,以减少护理的可变性。证据等级:3;
{"title":"Factors influencing likelihood of inpatient frenotomy in newborns with ankyloglossia","authors":"Jonathan M. Carnino ,&nbsp;Sanjeev Rampam ,&nbsp;Lindsay R. Salvati ,&nbsp;Yash V. Shroff ,&nbsp;Dean G. Kennedy ,&nbsp;Jessica R. Levi","doi":"10.1016/j.ijporl.2025.112644","DOIUrl":"10.1016/j.ijporl.2025.112644","url":null,"abstract":"<div><h3>Objective</h3><div>This study investigates national trends in inpatient frenotomy for newborns with ankyloglossia, focusing on the association between demographic, socioeconomic, and regional factors and the likelihood of undergoing the procedure.</div></div><div><h3>Methods</h3><div>Data from the 2016 Kid Inpatient Database (KID) were analyzed to identify hospitalized newborns diagnosed with ankyloglossia. Frenotomy procedures were identified using ICD-10 procedure codes. Chi-square tests were used to evaluate unadjusted associations between categorical variables and frenotomy utilization. Variables significant in univariate analysis were included in a multivariable logistic regression model to calculate adjusted odds ratios (OR) with 95 % confidence intervals (CI).</div></div><div><h3>Results</h3><div>Among 47,663 newborns with ankyloglossia, 34.8% underwent inpatient frenotomy. Factors independently associated with frenotomy included sex, race, hospital region, and household income. Female newborns had higher odds of frenotomy (OR 1.54, 95 % CI 1.47–1.61), whereas non-White racial groups had lower odds than White newborns. The Midwest had the highest likelihood of frenotomy (OR 3.08, 95 % CI 2.93–3.23), and newborns from the highest income quartile had reduced odds (OR 0.86, 95 % CI 0.80–0.92).</div></div><div><h3>Conclusions</h3><div>Significant disparities in inpatient frenotomy utilization exist based on demographic, socioeconomic, and regional factors. These findings underscore the need for standardized diagnostic criteria and equitable access to both surgical and non-surgical treatments. Future research should address the impact of these disparities on patient outcomes and explore targeted interventions to reduce variability in care.</div></div><div><h3>Level of evidence</h3><div>3.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"199 ","pages":"Article 112644"},"PeriodicalIF":1.3,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145512499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative outcomes of cricotracheal resection and laryngotracheal reconstruction in children with subglottic stenosis: A systematic review 环气管切除与喉气管重建术治疗儿童声门下狭窄的比较结果:一项系统综述
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-11 DOI: 10.1016/j.ijporl.2025.112645
Hannah Sturm , Saanvi Kohli , Saori W. Herman , Jared Levinson , Patrick Scheffler
{"title":"Comparative outcomes of cricotracheal resection and laryngotracheal reconstruction in children with subglottic stenosis: A systematic review","authors":"Hannah Sturm ,&nbsp;Saanvi Kohli ,&nbsp;Saori W. Herman ,&nbsp;Jared Levinson ,&nbsp;Patrick Scheffler","doi":"10.1016/j.ijporl.2025.112645","DOIUrl":"10.1016/j.ijporl.2025.112645","url":null,"abstract":"","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"199 ","pages":"Article 112645"},"PeriodicalIF":1.3,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145518269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using the gait disorientation test to measure spatial navigation in children with cochlear implants 用步态定向障碍测试测量植入人工耳蜗儿童的空间导航能力。
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-07 DOI: 10.1016/j.ijporl.2025.112632
Emma Kingsley , Andrew Wagner , Jessie N. Patterson , Amanda Chiao , Bisma Choudhry , Jennifer Christy , Kristen L. Janky

Objectives

The vestibular system is a collection of inertial organs that allow humans, and most other organisms, to remain appropriately oriented relative to earth's gravitational forces. A growing body of literature has identified a link between vestibular dysfunction and spatial cognitive abilities in both asymptomatic older adults and adults with confirmed vestibular loss. However, vestibular loss is also common among children with cochlear implants (CCI), with as many as 50 % showing evidence of concurrent vestibular dysfunction. Yet, how vestibular loss influences spatial cognition in CCI is limited. The primary objective of this study was to determine the impact of hearing loss and combined hearing plus vestibular loss on spatial cognitive performance by administering a mobility-based test of spatial navigation, the Gait Disorientation Test (GDT), in CCI and children with normal hearing and vestibular function.

Design

This was a cross-sectional study involving 84 children: 36 children with normal hearing (CNH), 31 CCI and normal vestibular function (CCI-NV), 9 CCI and unilateral vestibular loss (CCI-UVL) and 8 CCI and bilateral vestibular loss (CCI-BVL). The Bruininks Oseretsky Test of motor proficiency, 2nd edition (BOT-2) and the video head impulse test (vHIT) were performed alongside a measure of spatial navigation, the GDT, which was determined for each child by measuring differences in gait speed between eyes open and eyes closed walking conditions.

Results

There was no significant difference in GDT scores between the CNH (1.89 s), CCI-NV (1.91 s), CCI-UVL (2.28 s), and CCI-BVL (1.52 s) groups (Kruskal Wallis, H = 0.29, p = 0.96). Gait speed during the eyes closed portion of the GDT was not significantly different between the four groups (Kruskal Wallis, H = 1.53, p = 0.68); however, CNH (5.9 s) and CCI-BVL (6.21 s) each walked significantly slower than the CCI-NV (5.09 s) in the eyes open portion of the GDT. There was however an apparent stepwise change in BOT-2 balance scores, with lower performance amongst children with CCI and vestibular loss (Kruskal Wallis, H = 37.91, p < 0.001).

Conclusions

Unlike adults with vestibular loss, these data show that children with vestibular loss do not display significantly impaired spatial navigation relative to CNH and normal vestibular function. These data are consistent with the existence of unique compensatory responses to vestibular loss occurring later in life compared to at birth or early in development.
目的:前庭系统是一个惯性器官的集合,它允许人类和大多数其他生物相对于地球引力保持适当的方向。越来越多的文献发现,在无症状的老年人和证实有前庭功能丧失的成年人中,前庭功能障碍与空间认知能力之间存在联系。然而,前庭功能丧失在植入人工耳蜗(CCI)的儿童中也很常见,多达50%的儿童显示出并发前庭功能障碍的证据。然而,前庭功能丧失对CCI患者空间认知的影响尚不清楚。本研究的主要目的是通过对CCI和听力和前庭功能正常的儿童进行基于活动能力的空间导航测试,即步态失向测试(GDT),确定听力损失和合并听力和前庭功能损失对空间认知能力的影响。设计:这是一项涉及84名儿童的横断面研究:36名儿童听力正常(CNH), 31名CCI和前庭功能正常(CCI- nv), 9名CCI和单侧前庭功能丧失(CCI- uvl), 8名CCI和双侧前庭功能丧失(CCI- bvl)。bruinink Oseretsky运动熟练度测试(BOT-2)和视频头部脉冲测试(vHIT)与空间导航测量(GDT)一起进行,GDT是通过测量每个孩子在睁眼和闭眼行走条件下的步态速度差异来确定的。结果:CNH组(1.89 s)、CCI-NV组(1.91 s)、CCI-UVL组(2.28 s)、CCI-BVL组(1.52 s) GDT评分差异无统计学意义(Kruskal Wallis, H = 0.29, p = 0.96)。四组间GDT闭眼部分的步态速度无显著差异(Kruskal Wallis, H = 1.53, p = 0.68);然而,在GDT的睁眼部分,CNH (5.9 s)和CCI-BVL (6.21 s)的行走速度均明显慢于CCI-NV (5.09 s)。然而,BOT-2平衡评分有明显的逐步变化,CCI和前庭功能丧失的儿童表现较差(Kruskal Wallis, H = 37.91, p)。结论:与前庭功能丧失的成人不同,这些数据表明,与CNH和正常前庭功能相比,前庭功能丧失的儿童没有表现出明显的空间导航功能受损。与出生时或发育早期相比,这些数据与前庭功能丧失的独特代偿反应的存在是一致的。
{"title":"Using the gait disorientation test to measure spatial navigation in children with cochlear implants","authors":"Emma Kingsley ,&nbsp;Andrew Wagner ,&nbsp;Jessie N. Patterson ,&nbsp;Amanda Chiao ,&nbsp;Bisma Choudhry ,&nbsp;Jennifer Christy ,&nbsp;Kristen L. Janky","doi":"10.1016/j.ijporl.2025.112632","DOIUrl":"10.1016/j.ijporl.2025.112632","url":null,"abstract":"<div><h3>Objectives</h3><div>The vestibular system is a collection of inertial organs that allow humans, and most other organisms, to remain appropriately oriented relative to earth's gravitational forces. A growing body of literature has identified a link between vestibular dysfunction and spatial cognitive abilities in both asymptomatic older adults and adults with confirmed vestibular loss. However, vestibular loss is also common among children with cochlear implants (CCI), with as many as 50 % showing evidence of concurrent vestibular dysfunction. Yet, how vestibular loss influences spatial cognition in CCI is limited. The primary objective of this study was to determine the impact of hearing loss and combined hearing plus vestibular loss on spatial cognitive performance by administering a mobility-based test of spatial navigation, the Gait Disorientation Test (GDT), in CCI and children with normal hearing and vestibular function.</div></div><div><h3>Design</h3><div>This was a cross-sectional study involving 84 children: 36 children with normal hearing (CNH), 31 CCI and normal vestibular function (CCI-NV), 9 CCI and unilateral vestibular loss (CCI-UVL) and 8 CCI and bilateral vestibular loss (CCI-BVL). The Bruininks Oseretsky Test of motor proficiency, 2nd edition (BOT-2) and the video head impulse test (vHIT) were performed alongside a measure of spatial navigation, the GDT, which was determined for each child by measuring differences in gait speed between eyes open and eyes closed walking conditions.</div></div><div><h3>Results</h3><div>There was no significant difference in GDT scores between the CNH (1.89 s), CCI-NV (1.91 s), CCI-UVL (2.28 s), and CCI-BVL (1.52 s) groups (Kruskal Wallis, H = 0.29, p = 0.96). Gait speed during the eyes closed portion of the GDT was not significantly different between the four groups (Kruskal Wallis, H = 1.53, p = 0.68); however, CNH (5.9 s) and CCI-BVL (6.21 s) each walked significantly slower than the CCI-NV (5.09 s) in the eyes open portion of the GDT. There was however an apparent stepwise change in BOT-2 balance scores, with lower performance amongst children with CCI and vestibular loss (Kruskal Wallis, H = 37.91, p &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>Unlike adults with vestibular loss, these data show that children with vestibular loss do not display significantly impaired spatial navigation relative to CNH and normal vestibular function. These data are consistent with the existence of unique compensatory responses to vestibular loss occurring later in life compared to at birth or early in development.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"199 ","pages":"Article 112632"},"PeriodicalIF":1.3,"publicationDate":"2025-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145504010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Newborn hearing screening in gestational diabetes mellitus: A comparative study of GDMA1 and GDMA2 妊娠期糖尿病新生儿听力筛查:GDMA1和GDMA2的比较研究。
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2025-11-07 DOI: 10.1016/j.ijporl.2025.112641
Mehmet Mete Kirlangic , Merve Kirlangic , Ceren Ozcelik Gulcan , Batuhan Caglar , Ilknur Merve Turkyilmaz Bugan

Aim

Gestational diabetes mellitus (GDM) is a common metabolic disorder that affects both maternal and fetal health, with potential long-term complications. While its impact on neonatal outcomes is well-documented, its association with newborn hearing loss remains unclear. This study aims to evaluate the relationship between GDM subtypes—diet-controlled (GDMA1) and insulin-treated (GDMA2) —and newborn hearing screening results, emphasizing the need for targeted public health interventions.

Materials and methods

This retrospective study included pregnancy records from Kartal Dr. Lütfi Kırdar City Hospital. Pregnant women were categorized into three groups: healthy pregnancies (n = 282), GDMA1 (n = 140), and GDMA2 (n = 68). Hearing screening was performed using the auditory brainstem response (ABR) test. Newborns failing two consecutive tests were referred for further audiological evaluation and classified as having an adverse outcome. One-way ANOVA and post-hoc Bonferroni tests were used for statistical comparisons, with a significance level set at p < 0.05. To control for potential confounding variables, an analysis of covariance (ANCOVA) was conducted.

Results

Among the 490 newborns analyzed, the hearing screening failure rate was significantly higher in the GDMA2 group (26.5 %) compared to GDMA1 (10.0 %) and the control group (4.3 %) (p < 0.001). Additionally, GDMA2 pregnancies were associated with earlier delivery and higher birth weights compared to healthy pregnancies (p = 0.001). The study demonstrated a strong association between GDM severity and newborn hearing screening failure rates.

Conclusion

The findings indicate that newborns of GDM-affected pregnancies, particularly those requiring insulin treatment, have a higher risk of failing hearing screening tests. Given the potential long-term consequences of undetected hearing loss, early identification and intervention are crucial. Public health policies should incorporate enhanced prenatal monitoring and neonatal audiological screening programs for at-risk populations. Further research is needed to explore the underlying mechanisms linking GDM severity to auditory dysfunction.
目的:妊娠期糖尿病(GDM)是一种影响母体和胎儿健康的常见代谢紊乱,具有潜在的长期并发症。虽然它对新生儿结局的影响有充分的证据,但它与新生儿听力损失的关系尚不清楚。本研究旨在评估GDM亚型-饮食控制型(GDMA1)和胰岛素治疗型(GDMA2)与新生儿听力筛查结果的关系,强调有针对性的公共卫生干预的必要性。材料和方法:本回顾性研究包括Kartal Dr. ltfi Kırdar市医院的妊娠记录。孕妇被分为三组:健康孕妇(n = 282)、GDMA1孕妇(n = 140)和GDMA2孕妇(n = 68)。采用听觉脑干反应(ABR)试验进行听力筛查。连续两次测试失败的新生儿被转介进行进一步的听力学评估,并归类为有不良后果。结果:在分析的490名新生儿中,GDMA2组的听力筛查失败率(26.5%)明显高于GDMA1组(10.0%)和对照组(4.3 %)(p)。结论:研究结果表明,gdm影响妊娠的新生儿,特别是需要胰岛素治疗的新生儿,听力筛查失败的风险更高。考虑到未被发现的听力损失的潜在长期后果,早期识别和干预至关重要。公共卫生政策应包括对高危人群加强产前监测和新生儿听力学筛查计划。需要进一步研究GDM严重程度与听觉功能障碍之间的潜在机制。
{"title":"Newborn hearing screening in gestational diabetes mellitus: A comparative study of GDMA1 and GDMA2","authors":"Mehmet Mete Kirlangic ,&nbsp;Merve Kirlangic ,&nbsp;Ceren Ozcelik Gulcan ,&nbsp;Batuhan Caglar ,&nbsp;Ilknur Merve Turkyilmaz Bugan","doi":"10.1016/j.ijporl.2025.112641","DOIUrl":"10.1016/j.ijporl.2025.112641","url":null,"abstract":"<div><h3>Aim</h3><div>Gestational diabetes mellitus (GDM) is a common metabolic disorder that affects both maternal and fetal health, with potential long-term complications. While its impact on neonatal outcomes is well-documented, its association with newborn hearing loss remains unclear. This study aims to evaluate the relationship between GDM subtypes—diet-controlled (GDMA1) and insulin-treated (GDMA2) —and newborn hearing screening results, emphasizing the need for targeted public health interventions.</div></div><div><h3>Materials and methods</h3><div>This retrospective study included pregnancy records from Kartal Dr. Lütfi Kırdar City Hospital. Pregnant women were categorized into three groups: healthy pregnancies (n = 282), GDMA1 (n = 140), and GDMA2 (n = 68). Hearing screening was performed using the auditory brainstem response (ABR) test. Newborns failing two consecutive tests were referred for further audiological evaluation and classified as having an adverse outcome. One-way ANOVA and post-hoc Bonferroni tests were used for statistical comparisons, with a significance level set at p &lt; 0.05. To control for potential confounding variables, an analysis of covariance (ANCOVA) was conducted.</div></div><div><h3>Results</h3><div>Among the 490 newborns analyzed, the hearing screening failure rate was significantly higher in the GDMA2 group (26.5 %) compared to GDMA1 (10.0 %) and the control group (4.3 %) (p &lt; 0.001). Additionally, GDMA2 pregnancies were associated with earlier delivery and higher birth weights compared to healthy pregnancies (p = 0.001). The study demonstrated a strong association between GDM severity and newborn hearing screening failure rates.</div></div><div><h3>Conclusion</h3><div>The findings indicate that newborns of GDM-affected pregnancies, particularly those requiring insulin treatment, have a higher risk of failing hearing screening tests. Given the potential long-term consequences of undetected hearing loss, early identification and intervention are crucial. Public health policies should incorporate enhanced prenatal monitoring and neonatal audiological screening programs for at-risk populations. Further research is needed to explore the underlying mechanisms linking GDM severity to auditory dysfunction.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"199 ","pages":"Article 112641"},"PeriodicalIF":1.3,"publicationDate":"2025-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145495492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International journal of pediatric otorhinolaryngology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1