Pub Date : 2026-02-02DOI: 10.1001/jamanetworkopen.2025.56631
Anne J Maheux, Samir Akre-Bhide, Debra Boeldt, Jessica E Flannery, Zachary Richardson, Kaitlyn Burnell, Eva H Telzer, Scott H Kollins
Importance: As generative artificial intelligence (GenAI) tools become increasingly integrated into the daily lives of youth, it is critical to study their usage patterns and potential implications for mental health. While there is evidence of a rapid pace of adoption among adults, rates of GenAI use among youth remains largely undocumented.
Objective: To characterize GenAI application (app) usage among US youth, including adoption rates and time spent.
Design, setting, and participants: This cross-sectional study documented digital behavior of US youth extracted from a parental monitoring app. Participants were ages 4 to 17 years and were in families using a commercially available Aura app in the US. No identifying information was collected about the child except year of birth. Data were collected using passive sensing methods from naturalistic smart device use between September 2024 and April 2025. Data were analyzed in May and June 2025.
Main outcome and measures: Adoption rates (ie, number of youth ever accessing GenAI apps on their device) and time spent using GenAI (ie, average minutes accessing GenAI apps), measured by age and time period.
Results: In a cohort of 6488 participants, nearly 2072 youths (31.9%) used GenAI apps on their device. GenAI use was highest among teens (age 13 to 14 years, 899 of 2139 [42.0%]; age 15 to 17 years, 628 of 1246 [50.4%]), although adoption among preteens (age 10 to 12 years, 484 of 2366 [20.5%]) and school-aged children (age 8 to 9 years, 49 of 522 [9.4%]) was not trivial. GenAI usage was higher after school than at nighttime or during school. Overall, users spent a mean (SD) 2.37 (10.55) and a median (IQR) 0.18 (0.04-0.84) minutes a day using GenAI, yet large variances and skewed distributions suggest that a small subset of youth use GenAI extensively, with the heaviest users accessing GenAI for over 40 minutes a day.
Conclusions and relevance: In this cross-sectional study, Gen AI app use varied widely among participants, with up to half of adolescents having some use and a small subset engaging in heavy use. Future research must address individual differences in GenAI use to determine impacts on development.
{"title":"Generative Artificial Intelligence Applications Use Among US Youth.","authors":"Anne J Maheux, Samir Akre-Bhide, Debra Boeldt, Jessica E Flannery, Zachary Richardson, Kaitlyn Burnell, Eva H Telzer, Scott H Kollins","doi":"10.1001/jamanetworkopen.2025.56631","DOIUrl":"10.1001/jamanetworkopen.2025.56631","url":null,"abstract":"<p><strong>Importance: </strong>As generative artificial intelligence (GenAI) tools become increasingly integrated into the daily lives of youth, it is critical to study their usage patterns and potential implications for mental health. While there is evidence of a rapid pace of adoption among adults, rates of GenAI use among youth remains largely undocumented.</p><p><strong>Objective: </strong>To characterize GenAI application (app) usage among US youth, including adoption rates and time spent.</p><p><strong>Design, setting, and participants: </strong>This cross-sectional study documented digital behavior of US youth extracted from a parental monitoring app. Participants were ages 4 to 17 years and were in families using a commercially available Aura app in the US. No identifying information was collected about the child except year of birth. Data were collected using passive sensing methods from naturalistic smart device use between September 2024 and April 2025. Data were analyzed in May and June 2025.</p><p><strong>Main outcome and measures: </strong>Adoption rates (ie, number of youth ever accessing GenAI apps on their device) and time spent using GenAI (ie, average minutes accessing GenAI apps), measured by age and time period.</p><p><strong>Results: </strong>In a cohort of 6488 participants, nearly 2072 youths (31.9%) used GenAI apps on their device. GenAI use was highest among teens (age 13 to 14 years, 899 of 2139 [42.0%]; age 15 to 17 years, 628 of 1246 [50.4%]), although adoption among preteens (age 10 to 12 years, 484 of 2366 [20.5%]) and school-aged children (age 8 to 9 years, 49 of 522 [9.4%]) was not trivial. GenAI usage was higher after school than at nighttime or during school. Overall, users spent a mean (SD) 2.37 (10.55) and a median (IQR) 0.18 (0.04-0.84) minutes a day using GenAI, yet large variances and skewed distributions suggest that a small subset of youth use GenAI extensively, with the heaviest users accessing GenAI for over 40 minutes a day.</p><p><strong>Conclusions and relevance: </strong>In this cross-sectional study, Gen AI app use varied widely among participants, with up to half of adolescents having some use and a small subset engaging in heavy use. Future research must address individual differences in GenAI use to determine impacts on development.</p>","PeriodicalId":14694,"journal":{"name":"JAMA Network Open","volume":"9 2","pages":"e2556631"},"PeriodicalIF":9.7,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12865656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146104792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-02DOI: 10.1001/jamanetworkopen.2025.57332
David Adzrago, Kayo Fujimoto, J Michael Wilkerson, Typhanye V Dyer, Faustine Williams
<p><strong>Importance: </strong>Mental health problems, particularly anxiety and depression, remain among the leading causes of disease burden in the US. However, trends in anxiety and depression across disability status and demographics remain understudied.</p><p><strong>Objective: </strong>To examine trends in anxiety and depression prevalence among US adults from 2019 to 2023 by disability status and demographic characteristics.</p><p><strong>Design, setting, and participants: </strong>This cross-sectional study used national population-based data from the National Health Interview Surveys from 2019 to 2023. Data were collected from household probability samples of noninstitutionalized US civilian adults aged at least 18 years. Data analyses were performed from December 6, 2024, to November 19, 2025.</p><p><strong>Exposures: </strong>Disability status (measured using Washington Group on Disability Statistics Short Set on Functioning), race and ethnicity, sex, and nativity.</p><p><strong>Main outcomes and measures: </strong>The primary outcomes were self-reported anxiety or depression symptoms, assessed using the Washington Group on Disability Statistics Extended Set on Functioning. Joinpoint regression was used to estimate age-standardized prevalence trends and average annual percentage change (AAPC) across disability status, race and ethnicity, sex, and nativity.</p><p><strong>Results: </strong>A total of 150 220 adults were examined (81 525 [51.3%] female; 48 814 individuals [32.3%] aged 45-64 years; 126 051 individuals [81.1%] born in the US), including 16 172 Black individuals (11.9%), 20 427 Hispanic or Latino individuals (17.7%), 12 221 individuals (8.9%) who identified as another race or ethnicity, and 101 400 White individuals (61.4%). There were 15 519 respondents (8.2%) with general disability status and 60 248 respondents (42.3%) with anxiety or depression. From 2019 to 2023, anxiety or depression prevalence increased significantly among individuals without disabilities (AAPC, 3.93; 95% CI, 2.15-5.75). Prevalence increased across all racial and ethnic groups without disabilities, with the highest increases among Black respondents (AAPC, 4.77; 95% CI, 0.61-9.10) and respondents who identified as another race or ethnicity (AAPC, 6.95; 95% CI, 2.56-11.53). Prevalence increased only among females without disabilities (AAPC, 3.50; 95% CI, 2.14-4.87), while increases were observed among males with (AAPC, 3.25; 95% CI, 0.41-6.17) and without (AAPC, 4.62; 95% CI, 1.70-7.63) disabilities. Individuals born outside the US without disabilities experienced higher increases (AAPC, 5.57; 95% CI, 3.10-8.11) than those with disabilities (AAPC, 3.46; 95% CI, 0.06-6.98) and individuals born in the US without disabilities (AAPC, 3.75; 95% CI, 2.14-5.40). Across race and ethnicity, sex, and nativity intersections, Black female individuals born outside the US without disabilities exhibited the highest increase (AAPC, 14.89; 95% CI, 0.48-31.36).</p><p><st
{"title":"Anxiety or Depression Trends by Disability Status and Demographic Intersections in US Adults, 2019-2023.","authors":"David Adzrago, Kayo Fujimoto, J Michael Wilkerson, Typhanye V Dyer, Faustine Williams","doi":"10.1001/jamanetworkopen.2025.57332","DOIUrl":"10.1001/jamanetworkopen.2025.57332","url":null,"abstract":"<p><strong>Importance: </strong>Mental health problems, particularly anxiety and depression, remain among the leading causes of disease burden in the US. However, trends in anxiety and depression across disability status and demographics remain understudied.</p><p><strong>Objective: </strong>To examine trends in anxiety and depression prevalence among US adults from 2019 to 2023 by disability status and demographic characteristics.</p><p><strong>Design, setting, and participants: </strong>This cross-sectional study used national population-based data from the National Health Interview Surveys from 2019 to 2023. Data were collected from household probability samples of noninstitutionalized US civilian adults aged at least 18 years. Data analyses were performed from December 6, 2024, to November 19, 2025.</p><p><strong>Exposures: </strong>Disability status (measured using Washington Group on Disability Statistics Short Set on Functioning), race and ethnicity, sex, and nativity.</p><p><strong>Main outcomes and measures: </strong>The primary outcomes were self-reported anxiety or depression symptoms, assessed using the Washington Group on Disability Statistics Extended Set on Functioning. Joinpoint regression was used to estimate age-standardized prevalence trends and average annual percentage change (AAPC) across disability status, race and ethnicity, sex, and nativity.</p><p><strong>Results: </strong>A total of 150 220 adults were examined (81 525 [51.3%] female; 48 814 individuals [32.3%] aged 45-64 years; 126 051 individuals [81.1%] born in the US), including 16 172 Black individuals (11.9%), 20 427 Hispanic or Latino individuals (17.7%), 12 221 individuals (8.9%) who identified as another race or ethnicity, and 101 400 White individuals (61.4%). There were 15 519 respondents (8.2%) with general disability status and 60 248 respondents (42.3%) with anxiety or depression. From 2019 to 2023, anxiety or depression prevalence increased significantly among individuals without disabilities (AAPC, 3.93; 95% CI, 2.15-5.75). Prevalence increased across all racial and ethnic groups without disabilities, with the highest increases among Black respondents (AAPC, 4.77; 95% CI, 0.61-9.10) and respondents who identified as another race or ethnicity (AAPC, 6.95; 95% CI, 2.56-11.53). Prevalence increased only among females without disabilities (AAPC, 3.50; 95% CI, 2.14-4.87), while increases were observed among males with (AAPC, 3.25; 95% CI, 0.41-6.17) and without (AAPC, 4.62; 95% CI, 1.70-7.63) disabilities. Individuals born outside the US without disabilities experienced higher increases (AAPC, 5.57; 95% CI, 3.10-8.11) than those with disabilities (AAPC, 3.46; 95% CI, 0.06-6.98) and individuals born in the US without disabilities (AAPC, 3.75; 95% CI, 2.14-5.40). Across race and ethnicity, sex, and nativity intersections, Black female individuals born outside the US without disabilities exhibited the highest increase (AAPC, 14.89; 95% CI, 0.48-31.36).</p><p><st","PeriodicalId":14694,"journal":{"name":"JAMA Network Open","volume":"9 2","pages":"e2557332"},"PeriodicalIF":9.7,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12865658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146105626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-02DOI: 10.1001/jamanetworkopen.2025.56357
Suzanna M Zick, Dongru Chen, Richard E Harris, Grant Kruger, Amy Runyon, Ananda Sen, Sara Snyder, Celeste Leigh Pearce
<p><strong>Importance: </strong>Fatigue is a burdensome effect of ovarian cancer that is associated with poor sleep and quality of life. Self-acupressure is recommended in clinical guidelines but has substantial barriers to implementation. Use of a mobile app may address these barriers.</p><p><strong>Objective: </strong>To investigate whether 6 weeks of true self-acupressure (TSA), learned via a mobile app, improves cancer fatigue, sleep, and quality of life in women with ovarian cancer compared with sham self-acupressure (SSA) and usual care (UC) and whether changes are sustained during an 18-week washout period.</p><p><strong>Design, setting, and participants: </strong>This phase 3 single-blind randomized clinical trial was conducted from October 2019 to December 2023. Data collection ended in November 2024. Participants included ovarian cancer survivors who were fatigued (based on a Brief Fatigue Inventory [BFI] score ≥4) and who were recruited from tumor registries and social media.</p><p><strong>Intervention: </strong>Randomization (1:1:1) to 6 weeks of TSA or SSA, taught via mobile app, or UC.</p><p><strong>Main outcomes and measures: </strong>The primary outcome was the change in the BFI from baseline to week 6. Secondary analyses were the BFI score at week 24 and sleep disturbance (based on the Pittsburgh Sleep Quality Index) and quality of life (based on the Functional Assessment of Cancer Therapy-Ovarian) administered at baseline and at weeks 6, 12, and 24.</p><p><strong>Results: </strong>Among the 360 participants who were screened, 171 women were randomized (mean [SD] age, 56 [12] years). Of the 160 participants who were allocated to the arms, 53 (33.1%) received TSA, 56 (35.0%) received SSA, and 51 (31.9%) received UC. Of these, the proportion achieving a clinically normal fatigue level at the end of treatment was 58.5% for the TSA arm, 51.1% for the SSA arm, and 17.6% for the UC arm. At 6 weeks, the BFI change scores were significantly better in the TSA arm but not in the SSA arm when they were compared with the UC-only arm (TSA vs UC: adjusted mean difference, -1.23 [95% CI, -2.17 to -0.29] and SSA vs UC: adjusted mean difference, -0.91 [95% CI, -1.83 to 0.02]). TSA and SSA change scores did not differ significantly from one another. The relative benefit of self-acupressure compared with UC on fatigue persisted at 24 weeks (TSA vs UC: mean difference, -1.38 [95% CI, -2.36 to -0.41] and SSA vs UC: mean difference, -0.97 [95% CI, -1.93 to -0.02]). Neither TSA nor SSA was significantly different than UC or each other for sleep quality. Only TSA significantly improved quality of life vs UC (odds ratio, 2.85 [95% CI, 1.20 to 6.80]). Neither true nor sham self-acupressure led to any adverse events.</p><p><strong>Conclusions and relevance: </strong>In this randomized clinical trial, TSA and SSA significantly reduced fatigue compared with UC, and these changes were both clinically meaningful and sustained. No impact was observed on sleep q
{"title":"Self-Acupressure for Fatigue in Patients Surviving Ovarian Cancer: A Randomized Clinical Trial.","authors":"Suzanna M Zick, Dongru Chen, Richard E Harris, Grant Kruger, Amy Runyon, Ananda Sen, Sara Snyder, Celeste Leigh Pearce","doi":"10.1001/jamanetworkopen.2025.56357","DOIUrl":"10.1001/jamanetworkopen.2025.56357","url":null,"abstract":"<p><strong>Importance: </strong>Fatigue is a burdensome effect of ovarian cancer that is associated with poor sleep and quality of life. Self-acupressure is recommended in clinical guidelines but has substantial barriers to implementation. Use of a mobile app may address these barriers.</p><p><strong>Objective: </strong>To investigate whether 6 weeks of true self-acupressure (TSA), learned via a mobile app, improves cancer fatigue, sleep, and quality of life in women with ovarian cancer compared with sham self-acupressure (SSA) and usual care (UC) and whether changes are sustained during an 18-week washout period.</p><p><strong>Design, setting, and participants: </strong>This phase 3 single-blind randomized clinical trial was conducted from October 2019 to December 2023. Data collection ended in November 2024. Participants included ovarian cancer survivors who were fatigued (based on a Brief Fatigue Inventory [BFI] score ≥4) and who were recruited from tumor registries and social media.</p><p><strong>Intervention: </strong>Randomization (1:1:1) to 6 weeks of TSA or SSA, taught via mobile app, or UC.</p><p><strong>Main outcomes and measures: </strong>The primary outcome was the change in the BFI from baseline to week 6. Secondary analyses were the BFI score at week 24 and sleep disturbance (based on the Pittsburgh Sleep Quality Index) and quality of life (based on the Functional Assessment of Cancer Therapy-Ovarian) administered at baseline and at weeks 6, 12, and 24.</p><p><strong>Results: </strong>Among the 360 participants who were screened, 171 women were randomized (mean [SD] age, 56 [12] years). Of the 160 participants who were allocated to the arms, 53 (33.1%) received TSA, 56 (35.0%) received SSA, and 51 (31.9%) received UC. Of these, the proportion achieving a clinically normal fatigue level at the end of treatment was 58.5% for the TSA arm, 51.1% for the SSA arm, and 17.6% for the UC arm. At 6 weeks, the BFI change scores were significantly better in the TSA arm but not in the SSA arm when they were compared with the UC-only arm (TSA vs UC: adjusted mean difference, -1.23 [95% CI, -2.17 to -0.29] and SSA vs UC: adjusted mean difference, -0.91 [95% CI, -1.83 to 0.02]). TSA and SSA change scores did not differ significantly from one another. The relative benefit of self-acupressure compared with UC on fatigue persisted at 24 weeks (TSA vs UC: mean difference, -1.38 [95% CI, -2.36 to -0.41] and SSA vs UC: mean difference, -0.97 [95% CI, -1.93 to -0.02]). Neither TSA nor SSA was significantly different than UC or each other for sleep quality. Only TSA significantly improved quality of life vs UC (odds ratio, 2.85 [95% CI, 1.20 to 6.80]). Neither true nor sham self-acupressure led to any adverse events.</p><p><strong>Conclusions and relevance: </strong>In this randomized clinical trial, TSA and SSA significantly reduced fatigue compared with UC, and these changes were both clinically meaningful and sustained. No impact was observed on sleep q","PeriodicalId":14694,"journal":{"name":"JAMA Network Open","volume":"9 2","pages":"e2556357"},"PeriodicalIF":9.7,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12878437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146124731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-02DOI: 10.1001/jamanetworkopen.2025.56117
Lauren A Eberly, Carmen George, Sharon Sandman, Denee Bex, Matt Chandra, Kaitlyn Shultz, Ada Tennison, Rebecca Wickre, Bennett Wickre, Larissa Morgan, Leah Gray, Mackenzie Bolas, Benjamin Feliciano, DezBaa Damon-Mallette, Erica Lindsey, Jacob Manche, Pamela Detsoi-Smiley, Paula Mora, Maricruz Merino, Sonya S Shin
<p><strong>Importance: </strong>The ongoing consequences of settler colonialism produce adverse structural drivers, particularly nutrition insecurity, that contribute to cardiovascular health disparities among Indigenous populations. There is increased focus in Native communities to reclaim traditional precontact foods to improve health. Therefore, a locally sourced, Indigenous, medically tailored meal delivery program-MUTTON-HF (Medically Utilized Tailored Traditional Foods to Optimize Nutrition in Heart Failure)-was developed to improve health outcomes.</p><p><strong>Objective: </strong>To determine implementation outcomes, including feasibility and acceptability, as well as to explore preintervention vs postintervention health measures of a medically tailored meal program incorporating traditional foods and recipes for patients with heart failure in rural Navajo Nation.</p><p><strong>Design, setting, and participants: </strong>The single-arm pilot nonrandomized clinical trial was conducted from October 7, 2024, to February 3, 2025, to evaluate implementation and health outcomes of the MUTTON-HF program. Participants included adults (≥18 years) with a diagnosis of heart failure who were receiving care at one of 2 Indian Health Service sites in rural Navajo Nation.</p><p><strong>Intervention: </strong>Patients received 14 culturally and medically tailored meals weekly (2 meals daily) for 4 weeks.</p><p><strong>Main outcomes and measures: </strong>The primary outcomes were intervention feasibility and acceptability, assessed with surveys, qualitative interviews, and programmatic data at 30 days. Intervention feasibility was determined by evaluating the number and percentage of meal boxes successfully received by each patient. Acceptability was assessed using the Acceptability of Intervention Measure (AIM) (score range, 4-20), patient program ratings (range, 1-10), and the Net Promoter Score. Secondary outcomes, which were assessed via surveys and medical record review, included intervention adoption and fidelity, feasibility for community partners (including farmers and ranchers, using the Feasibility of Intervention Measure [score range, 4-20]), and preintervention vs postintervention health measures (eg, clinical biomarkers, food insecurity [based on the US Department of Agriculture 6-item Short-Form Food Security Survey Module], 12-item Kansas City Cardiomyopathy Questionnaire [KCCQ] scores, and Cultural Connectedness Scale [CCS] scores).</p><p><strong>Results: </strong>This study enrolled 20 American Indian patients (mean [SD] age, 58.2 [11.7] years; 13 were male [65.0%]) residing in communities exceeding a 136-km radius in Arizona and New Mexico. Patients had a mean (SD) left ventricular ejection fraction of 40.0% (16.0%). Of the 80 weekly meal boxes, 72 (90.0%) were successfully received by patients. The mean (SD) AIM score was 16.9 (3.1), the mean (SD) patient program rating was 8.6 (1.6), and the Net Promoter Score was 45.0%. Most patient
{"title":"Feasibility of an Indigenous Food Is Medicine Program for Patients With Heart Failure in Rural Navajo Nation: The MUTTON-HF Nonrandomized Clinical Trial.","authors":"Lauren A Eberly, Carmen George, Sharon Sandman, Denee Bex, Matt Chandra, Kaitlyn Shultz, Ada Tennison, Rebecca Wickre, Bennett Wickre, Larissa Morgan, Leah Gray, Mackenzie Bolas, Benjamin Feliciano, DezBaa Damon-Mallette, Erica Lindsey, Jacob Manche, Pamela Detsoi-Smiley, Paula Mora, Maricruz Merino, Sonya S Shin","doi":"10.1001/jamanetworkopen.2025.56117","DOIUrl":"10.1001/jamanetworkopen.2025.56117","url":null,"abstract":"<p><strong>Importance: </strong>The ongoing consequences of settler colonialism produce adverse structural drivers, particularly nutrition insecurity, that contribute to cardiovascular health disparities among Indigenous populations. There is increased focus in Native communities to reclaim traditional precontact foods to improve health. Therefore, a locally sourced, Indigenous, medically tailored meal delivery program-MUTTON-HF (Medically Utilized Tailored Traditional Foods to Optimize Nutrition in Heart Failure)-was developed to improve health outcomes.</p><p><strong>Objective: </strong>To determine implementation outcomes, including feasibility and acceptability, as well as to explore preintervention vs postintervention health measures of a medically tailored meal program incorporating traditional foods and recipes for patients with heart failure in rural Navajo Nation.</p><p><strong>Design, setting, and participants: </strong>The single-arm pilot nonrandomized clinical trial was conducted from October 7, 2024, to February 3, 2025, to evaluate implementation and health outcomes of the MUTTON-HF program. Participants included adults (≥18 years) with a diagnosis of heart failure who were receiving care at one of 2 Indian Health Service sites in rural Navajo Nation.</p><p><strong>Intervention: </strong>Patients received 14 culturally and medically tailored meals weekly (2 meals daily) for 4 weeks.</p><p><strong>Main outcomes and measures: </strong>The primary outcomes were intervention feasibility and acceptability, assessed with surveys, qualitative interviews, and programmatic data at 30 days. Intervention feasibility was determined by evaluating the number and percentage of meal boxes successfully received by each patient. Acceptability was assessed using the Acceptability of Intervention Measure (AIM) (score range, 4-20), patient program ratings (range, 1-10), and the Net Promoter Score. Secondary outcomes, which were assessed via surveys and medical record review, included intervention adoption and fidelity, feasibility for community partners (including farmers and ranchers, using the Feasibility of Intervention Measure [score range, 4-20]), and preintervention vs postintervention health measures (eg, clinical biomarkers, food insecurity [based on the US Department of Agriculture 6-item Short-Form Food Security Survey Module], 12-item Kansas City Cardiomyopathy Questionnaire [KCCQ] scores, and Cultural Connectedness Scale [CCS] scores).</p><p><strong>Results: </strong>This study enrolled 20 American Indian patients (mean [SD] age, 58.2 [11.7] years; 13 were male [65.0%]) residing in communities exceeding a 136-km radius in Arizona and New Mexico. Patients had a mean (SD) left ventricular ejection fraction of 40.0% (16.0%). Of the 80 weekly meal boxes, 72 (90.0%) were successfully received by patients. The mean (SD) AIM score was 16.9 (3.1), the mean (SD) patient program rating was 8.6 (1.6), and the Net Promoter Score was 45.0%. Most patient","PeriodicalId":14694,"journal":{"name":"JAMA Network Open","volume":"9 2","pages":"e2556117"},"PeriodicalIF":9.7,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12881988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-02DOI: 10.1001/jamanetworkopen.2025.56111
John L Havlik, Keith Humphreys
{"title":"Costs and Outcomes in Telemedicine-Can \"House Calls\" Make Sense and Cents?","authors":"John L Havlik, Keith Humphreys","doi":"10.1001/jamanetworkopen.2025.56111","DOIUrl":"https://doi.org/10.1001/jamanetworkopen.2025.56111","url":null,"abstract":"","PeriodicalId":14694,"journal":{"name":"JAMA Network Open","volume":"9 2","pages":"e2556111"},"PeriodicalIF":9.7,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-02DOI: 10.1001/jamanetworkopen.2025.55890
Jeanette A Stingone, Katharine H McVeigh, Lidiya Lednyak
Importance: National monitoring surveys indicate that developmental disabilities among US children constitute a substantial public health issue. While scientific literature documents the benefits of targeted, developmental interventions, there has been less study of formal early intervention (EI) services provided through Part C of the Individuals With Disabilities Education Act.
Objective: To assess the population-level utilization of the New York City EI program and estimate the association between receipt of EI services before 3 years of age and academic achievement later in childhood.
Design, setting, and participants: This retrospective cohort study was performed within an administrative data linkage of public health and educational data systems in New York City, with records from January 1, 1994, to December 31, 2007. Participants included children born in New York City between January 1, 1994, and December 31, 1998, who attended public elementary school for third grade. Analyses were conducted from January 1, 2023, to December 31, 2024.
Exposure: Any use of EI services from birth through 3 years of age.
Main outcomes and measures: The primary outcomes were standardized test scores in math and English language arts (ELA) in third grade. After propensity score matching, linear and log-binomial regression were used to estimate differences in standardized test scores and incidence ratios of meeting test-based standards, comparing individuals who did and did not receive EI services.
Results: The study population consisted of 214 370 children with records through third grade. Of the 13 022 children who had received EI services (6.1%) before 3 years of age, 8516 (65.4%) were male (mean [SD] gestational age, 37.5 [3.8] weeks). When examining third grade standardized test scores, higher absolute test scores were observed among children who received EI in ELA (estimate, 0.045; 95% CI, 0.021-0.069) and greater incidence of meeting test-based standards in both math (incidence ratio, 1.08; 95% CI, 1.06-1.10) and ELA (incidence ratio, 1.09; 95% CI, 1.07-1.12) when comparing propensity score-matched samples. Evidence of heterogeneity was observed, as individuals who required special education, those from households with lower socioeconomic status, and those born to immigrant mothers had greater test score benefits associated with EI.
Conclusions and relevance: The findings of this cohort study suggest that EI services for children younger than 3 years with moderate to severe developmental delays or disabilities had tangible academic benefits later in childhood. Future research should investigate the implementation of EI services among individuals with different diagnoses and developmental delays to determine the most beneficial service plans for children with differing needs.
{"title":"Early Intervention Developmental Programming and Childhood Academic Outcomes.","authors":"Jeanette A Stingone, Katharine H McVeigh, Lidiya Lednyak","doi":"10.1001/jamanetworkopen.2025.55890","DOIUrl":"10.1001/jamanetworkopen.2025.55890","url":null,"abstract":"<p><strong>Importance: </strong>National monitoring surveys indicate that developmental disabilities among US children constitute a substantial public health issue. While scientific literature documents the benefits of targeted, developmental interventions, there has been less study of formal early intervention (EI) services provided through Part C of the Individuals With Disabilities Education Act.</p><p><strong>Objective: </strong>To assess the population-level utilization of the New York City EI program and estimate the association between receipt of EI services before 3 years of age and academic achievement later in childhood.</p><p><strong>Design, setting, and participants: </strong>This retrospective cohort study was performed within an administrative data linkage of public health and educational data systems in New York City, with records from January 1, 1994, to December 31, 2007. Participants included children born in New York City between January 1, 1994, and December 31, 1998, who attended public elementary school for third grade. Analyses were conducted from January 1, 2023, to December 31, 2024.</p><p><strong>Exposure: </strong>Any use of EI services from birth through 3 years of age.</p><p><strong>Main outcomes and measures: </strong>The primary outcomes were standardized test scores in math and English language arts (ELA) in third grade. After propensity score matching, linear and log-binomial regression were used to estimate differences in standardized test scores and incidence ratios of meeting test-based standards, comparing individuals who did and did not receive EI services.</p><p><strong>Results: </strong>The study population consisted of 214 370 children with records through third grade. Of the 13 022 children who had received EI services (6.1%) before 3 years of age, 8516 (65.4%) were male (mean [SD] gestational age, 37.5 [3.8] weeks). When examining third grade standardized test scores, higher absolute test scores were observed among children who received EI in ELA (estimate, 0.045; 95% CI, 0.021-0.069) and greater incidence of meeting test-based standards in both math (incidence ratio, 1.08; 95% CI, 1.06-1.10) and ELA (incidence ratio, 1.09; 95% CI, 1.07-1.12) when comparing propensity score-matched samples. Evidence of heterogeneity was observed, as individuals who required special education, those from households with lower socioeconomic status, and those born to immigrant mothers had greater test score benefits associated with EI.</p><p><strong>Conclusions and relevance: </strong>The findings of this cohort study suggest that EI services for children younger than 3 years with moderate to severe developmental delays or disabilities had tangible academic benefits later in childhood. Future research should investigate the implementation of EI services among individuals with different diagnoses and developmental delays to determine the most beneficial service plans for children with differing needs.</p>","PeriodicalId":14694,"journal":{"name":"JAMA Network Open","volume":"9 2","pages":"e2555890"},"PeriodicalIF":9.7,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12887746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-02DOI: 10.1001/jamanetworkopen.2025.58329
Marilyn D Thomas, Carol Wei, Min Hee Kim, Jennifer Manly, Suzanne E Judd, Justin S White, Virginia J Howard, Christina Mangurian, Rita Hamad, M Maria Glymour
Importance: Black adults may derive long-term cognitive benefits from attendance at a historically Black college or university (HBCU) compared with a predominantly White institution (PWI). This association has not been evaluated in a nationwide sample.
Objective: To estimate the association between HBCU vs PWI attendance and cognitive health among later-life Black adults.
Design, setting, and participants: This cohort study used data from the Reasons for Geographic and Racial Differences in Stroke study, a prospective cohort study that recruited Black and White US adults aged 45 years and older during 2003 to 2007. The national cohort oversampled Black individuals and residents from the Stroke Belt (56%), a group of 8 Southern states defined by excess stroke mortality. The analytic sample included Black participants who attended high school in a state with an HBCU and attended college. Analysis was conducted from February to September 2025.
Exposure: Participants self-reported each college ever attended, classified as a PWI (reference) or HBCU.
Main outcomes and measures: Assessments of memory, language, and global cognition were conducted during follow-up every 6 months (2006-2021). Cognitive measures were standardized (ie, z-transformed). Linear regression was used to estimate the average treatment effect (ATE) using inverse of probability of treatment weighting. Additional analyses evaluated potential modification by being college-aged before 1955 (during legal racial segregation), 1955 to 1964 (during sanctioned racial discrimination), or after 1964.
Results: Among 1978 Black college-goers (mean [SD] age at first assessment, 61.8 [8.2] years; 1333 [67.4%] female), 699 (35.3%) attended an HBCU, 1952 (98.7%) completed a memory assessment, 1970 (99.6%) completed a language assessment, and 530 (26.8%) completed both assessments during the same follow-up visit. Compared with PWI attendance, HBCU attendance was associated with better z-scored memory (ATE, 0.13; 95% CI, 0.05-0.21), language (ATE, 0.19; 95% CI, 0.08-0.29), and global cognition (ATE, 0.22; 95% CI, 0.09-0.34). Estimates were consistent for individuals who were college-aged after 1955 but were not statistically significant among respondents who were college-aged prior to 1955.
Conclusions and relevance: In this cohort study using a national dataset, HBCU attendance was associated with better cognition compared with PWI attendance for aging Black adults, which held for those attending college before and after legal racial segregation and sanctioned racial discrimination in education.
{"title":"Historically Black College or University Attendance and Cognition in US Black Adults.","authors":"Marilyn D Thomas, Carol Wei, Min Hee Kim, Jennifer Manly, Suzanne E Judd, Justin S White, Virginia J Howard, Christina Mangurian, Rita Hamad, M Maria Glymour","doi":"10.1001/jamanetworkopen.2025.58329","DOIUrl":"10.1001/jamanetworkopen.2025.58329","url":null,"abstract":"<p><strong>Importance: </strong>Black adults may derive long-term cognitive benefits from attendance at a historically Black college or university (HBCU) compared with a predominantly White institution (PWI). This association has not been evaluated in a nationwide sample.</p><p><strong>Objective: </strong>To estimate the association between HBCU vs PWI attendance and cognitive health among later-life Black adults.</p><p><strong>Design, setting, and participants: </strong>This cohort study used data from the Reasons for Geographic and Racial Differences in Stroke study, a prospective cohort study that recruited Black and White US adults aged 45 years and older during 2003 to 2007. The national cohort oversampled Black individuals and residents from the Stroke Belt (56%), a group of 8 Southern states defined by excess stroke mortality. The analytic sample included Black participants who attended high school in a state with an HBCU and attended college. Analysis was conducted from February to September 2025.</p><p><strong>Exposure: </strong>Participants self-reported each college ever attended, classified as a PWI (reference) or HBCU.</p><p><strong>Main outcomes and measures: </strong>Assessments of memory, language, and global cognition were conducted during follow-up every 6 months (2006-2021). Cognitive measures were standardized (ie, z-transformed). Linear regression was used to estimate the average treatment effect (ATE) using inverse of probability of treatment weighting. Additional analyses evaluated potential modification by being college-aged before 1955 (during legal racial segregation), 1955 to 1964 (during sanctioned racial discrimination), or after 1964.</p><p><strong>Results: </strong>Among 1978 Black college-goers (mean [SD] age at first assessment, 61.8 [8.2] years; 1333 [67.4%] female), 699 (35.3%) attended an HBCU, 1952 (98.7%) completed a memory assessment, 1970 (99.6%) completed a language assessment, and 530 (26.8%) completed both assessments during the same follow-up visit. Compared with PWI attendance, HBCU attendance was associated with better z-scored memory (ATE, 0.13; 95% CI, 0.05-0.21), language (ATE, 0.19; 95% CI, 0.08-0.29), and global cognition (ATE, 0.22; 95% CI, 0.09-0.34). Estimates were consistent for individuals who were college-aged after 1955 but were not statistically significant among respondents who were college-aged prior to 1955.</p><p><strong>Conclusions and relevance: </strong>In this cohort study using a national dataset, HBCU attendance was associated with better cognition compared with PWI attendance for aging Black adults, which held for those attending college before and after legal racial segregation and sanctioned racial discrimination in education.</p>","PeriodicalId":14694,"journal":{"name":"JAMA Network Open","volume":"9 2","pages":"e2558329"},"PeriodicalIF":9.7,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12895292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146157057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-02DOI: 10.1001/jamanetworkopen.2025.56867
Haya Kaliounji, Benjamin A Steinberg
{"title":"Institutional Factors and Shared Decision-Making for Atrial Fibrillation.","authors":"Haya Kaliounji, Benjamin A Steinberg","doi":"10.1001/jamanetworkopen.2025.56867","DOIUrl":"https://doi.org/10.1001/jamanetworkopen.2025.56867","url":null,"abstract":"","PeriodicalId":14694,"journal":{"name":"JAMA Network Open","volume":"9 2","pages":"e2556867"},"PeriodicalIF":9.7,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146180104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-02DOI: 10.1001/jamanetworkopen.2025.59883
Jennifer N Felder, Daisy León-Martínez, Deborah Karasek, Venise Curry, Kristin Carraway, Patience A Afulani, Bridgette Blebu, Brittany Chambers-Butcher, Kimberly Coleman-Phox, Bethany J Simard, Cinthia Blat, Mary A Garza, Charles E McCulloch, Miriam Kuppermann
<p><strong>Importance: </strong>Racial, ethnic, and income disparities in perinatal depression prevalence and treatment are partially driven by social determinants of health. Effective treatments addressing these determinants are needed.</p><p><strong>Objective: </strong>To determine whether enhanced group prenatal care (eGPC) outperforms enhanced individual prenatal care (eIPC) for reducing perinatal depressive symptoms.</p><p><strong>Design, setting, and participants: </strong>This randomized clinical trial was conduced in 10 Medicaid-serving clinics in California's San Joaquin Valley, enrolling English- or Spanish-speaking Medicaid-eligible pregnant individuals at less than 25 weeks' gestation, from November 2019 to January 2024, with 2 follow-up surveys through 12 weeks postpartum. Analyses were conducted as intention-to-treat. Data were analyzed from December 2024 to December 2025.</p><p><strong>Interventions: </strong>Participants were randomized to eIPC or eGPC. eIPC enhancements included assessments tailored to individual psychosocial, clinical, oral health, and substance use needs. eGPC enhancements included childcare, perinatal mental health screening and referral, transportation stipends, free groceries, and information on community resources.</p><p><strong>Main outcomes and measures: </strong>The primary outcome was depression, operationalized as change in Patient Health Questionnaire-9 scores from baseline to 3 months postpartum. Outcomes were assessed by masked assessors.</p><p><strong>Results: </strong>Of 1663 individuals assessed, 678 were enrolled and randomized; 4 withdrew consent, yielding an analyzed sample of 674 participants (mean [SD] age, 27.0 [5.8] years), including 50 African American or Black participants (7.4%); 37 biracial, multiracial, or multiethnic participants (5.5%); 485 Latine participants (72.0%); 77 White participants (11.4%); and 24 participants who identified as another race or ethnicity (3.6%). After randomization, there were 294 participants in the eGPC group and 380 participants in the eIPC group. No difference in reductions in depressive symptom severity from baseline to 3 months postpartum by randomization group was observed (Cohen d for between-group change, 0.1; 95% CI, -0.1 to 0.3; P = .45), adjusting for baseline depressive symptom severity, self-reported history of a mental health condition, language, and calendar time at enrollment. Instead, participants in both groups experienced small to moderate reductions in depression symptoms from baseline to 3 months postpartum (eGPC: mean [SD] difference, -2.2 [5.3]; Cohen d = -0.4; 95% CI, -0.6 to -0.3; P < .001; eIPC: mean [SD] difference, -1.6 [4.5]; Cohen d = -0.5; 95% CI, -0.6 to -0.4; P < .001).</p><p><strong>Conclusions and relevance: </strong>In this randomized clinical trial of pregnant, low-income, primarily Latine individuals, statistically significant improvements were observed in depressive symptom severity from baseline to postpartum, regardl
重要性:围产期抑郁症患病率和治疗方面的种族、民族和收入差异部分是由健康的社会决定因素驱动的。需要针对这些决定因素的有效治疗。目的:确定加强群体产前护理(eGPC)是否优于加强个人产前护理(eIPC)减轻围产期抑郁症状。设计、环境和参与者:这项随机临床试验在加利福尼亚州圣华金谷的10家医疗补助服务诊所进行,从2019年11月到2024年1月,招募了怀孕不到25周的符合医疗补助条件的英语或西班牙语孕妇,并进行了两次随访调查,直到产后12周。分析作为意向治疗进行。数据分析时间为2024年12月至2025年12月。干预措施:参与者随机分为eIPC组和eGPC组。eIPC的改进包括针对个人心理社会、临床、口腔健康和药物使用需求量身定制的评估。增强的eGPC包括儿童保育、围产期心理健康筛查和转诊、交通补贴、免费食品杂货以及社区资源信息。主要结局和测量:主要结局是抑郁,通过患者健康问卷-9评分从基线到产后3个月的变化来实现。结果由匿名评估者评估。结果:在1663名被评估的个体中,678名被纳入并随机化;4人撤回同意,共分析了674名参与者(平均[SD]年龄27.0[5.8]岁),其中包括50名非裔美国人或黑人参与者(7.4%);37名混血、多种族或多民族参与者(5.5%);拉丁裔参与者485人(72.0%);白人77人(11.4%);24名参与者认为自己是另一个种族或民族(3.6%)。随机分组后,eGPC组有294人,eIPC组有380人。从基线到产后3个月,随机分组在抑郁症状严重程度的减轻方面没有观察到差异(Cohen d组间变化,0.1;95% CI, -0.1 ~ 0.3; P =。45),调整基线抑郁症状严重程度、自我报告的精神健康状况史、语言和入组时的日历时间。相反,从基线到产后3个月,两组参与者的抑郁症状都有小到中度的减轻(eGPC:平均[SD]差异,-2.2 [5.3];Cohen d = -0.4; 95% CI, -0.6至-0.3;P)结论和相关性:在这项针对孕妇、低收入、主要是拉丁裔个体的随机临床试验中,无论产前护理类型如何,从基线到产后,抑郁症状严重程度均有统计学意义的改善。没有证据表明加强产前护理对改善抑郁症状有什么不同。试验注册:ClinicalTrials.gov标识符:NCT04154423。
{"title":"Enhanced Prenatal Care Models and Postpartum Depression: The EMBRACE Randomized Clinical Trial.","authors":"Jennifer N Felder, Daisy León-Martínez, Deborah Karasek, Venise Curry, Kristin Carraway, Patience A Afulani, Bridgette Blebu, Brittany Chambers-Butcher, Kimberly Coleman-Phox, Bethany J Simard, Cinthia Blat, Mary A Garza, Charles E McCulloch, Miriam Kuppermann","doi":"10.1001/jamanetworkopen.2025.59883","DOIUrl":"https://doi.org/10.1001/jamanetworkopen.2025.59883","url":null,"abstract":"<p><strong>Importance: </strong>Racial, ethnic, and income disparities in perinatal depression prevalence and treatment are partially driven by social determinants of health. Effective treatments addressing these determinants are needed.</p><p><strong>Objective: </strong>To determine whether enhanced group prenatal care (eGPC) outperforms enhanced individual prenatal care (eIPC) for reducing perinatal depressive symptoms.</p><p><strong>Design, setting, and participants: </strong>This randomized clinical trial was conduced in 10 Medicaid-serving clinics in California's San Joaquin Valley, enrolling English- or Spanish-speaking Medicaid-eligible pregnant individuals at less than 25 weeks' gestation, from November 2019 to January 2024, with 2 follow-up surveys through 12 weeks postpartum. Analyses were conducted as intention-to-treat. Data were analyzed from December 2024 to December 2025.</p><p><strong>Interventions: </strong>Participants were randomized to eIPC or eGPC. eIPC enhancements included assessments tailored to individual psychosocial, clinical, oral health, and substance use needs. eGPC enhancements included childcare, perinatal mental health screening and referral, transportation stipends, free groceries, and information on community resources.</p><p><strong>Main outcomes and measures: </strong>The primary outcome was depression, operationalized as change in Patient Health Questionnaire-9 scores from baseline to 3 months postpartum. Outcomes were assessed by masked assessors.</p><p><strong>Results: </strong>Of 1663 individuals assessed, 678 were enrolled and randomized; 4 withdrew consent, yielding an analyzed sample of 674 participants (mean [SD] age, 27.0 [5.8] years), including 50 African American or Black participants (7.4%); 37 biracial, multiracial, or multiethnic participants (5.5%); 485 Latine participants (72.0%); 77 White participants (11.4%); and 24 participants who identified as another race or ethnicity (3.6%). After randomization, there were 294 participants in the eGPC group and 380 participants in the eIPC group. No difference in reductions in depressive symptom severity from baseline to 3 months postpartum by randomization group was observed (Cohen d for between-group change, 0.1; 95% CI, -0.1 to 0.3; P = .45), adjusting for baseline depressive symptom severity, self-reported history of a mental health condition, language, and calendar time at enrollment. Instead, participants in both groups experienced small to moderate reductions in depression symptoms from baseline to 3 months postpartum (eGPC: mean [SD] difference, -2.2 [5.3]; Cohen d = -0.4; 95% CI, -0.6 to -0.3; P < .001; eIPC: mean [SD] difference, -1.6 [4.5]; Cohen d = -0.5; 95% CI, -0.6 to -0.4; P < .001).</p><p><strong>Conclusions and relevance: </strong>In this randomized clinical trial of pregnant, low-income, primarily Latine individuals, statistically significant improvements were observed in depressive symptom severity from baseline to postpartum, regardl","PeriodicalId":14694,"journal":{"name":"JAMA Network Open","volume":"9 2","pages":"e2559883"},"PeriodicalIF":9.7,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}