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In-Hospital Adverse Events in Heart Failure Patients: Incidence and Association with 90-Day Mortality 心衰患者的院内不良事件:发病率及其与90天死亡率的关系
IF 2.3 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-03-27 DOI: 10.1016/j.jcjq.2025.03.003
Mohammed Yousufuddin MD, MSc (is Critical Care Physician and Hospitalist, Department of Hospital Internal Medicine, Mayo Clinic Health System, Austin, Minnesota), Mohamad H. Yamani MD (is Cardiologist, Department of Cardiovascular Medicine, Circulatory Failure, Mayo Clinic, Jacksonville, Florida), Daniel DeSimone MD (is Infectious Disease Specialist and Internist, Division of Public Health, Infectious Diseases and Occupational Medicine, Mayo Clinic, Rochester, Minnesota), Ebrahim Barkoudah MD, MPH, MBA (is System Chief of Hospital Medicine and Regional Chief Medical Officer and Chief Quality Officer, Baystate Health, Springfield, Massachusetts), Muhammad Waqas Tahir MD (is Internist, Department of Hospital Internal Medicine, Mayo Clinic, Jacksonville, Florida), Zeliang Ma MD, PhD (is Visiting Research Fellow, Department of Hospital Internal Medicine, Mayo Clinic Health System), Fatmaelzahraa Badr MBBCh (is Research Fellow, Department of Hospital Internal Medicine, Mayo Clinic Health System), Ibrahim A. Gomaa MD (is Research Fellow, Department of Hospital Internal Medicine, Mayo Clinic Health System), Sara Aboelmaaty MD (is Research Fellow, Department of Hospital Internal Medicine, Mayo Clinic Health System), Sumit Bhagra MD (is Chair of Endocrinology, Division of Endocrinology and Metabolism, Mayo Clinic Health System), Gregg C. Fonarow MD (is Professor of Clinical Medicine, Division of Cardiology, University of California, Los Angeles), Mohammad H. Murad MD, MPH (is Internist and General Preventive Medicine Specialist, Division of Public Health, Infectious Diseases and Occupational Medicine, Mayo Clinic, Rochester, Minnesota. Please address correspondence to Mohammed Yousufuddin)

Background

In-hospital adverse events (IHAEs) are key patient safety indicators but are not comprehensively assessed among patients hospitalized for heart failure (HF). The authors aimed to determine the association of IHAEs with downstream outcomes.

Methods

This retrospective multicenter cohort study analyzed data from patients hospitalized for HF in 17 acute care hospitals (2010–2023). The research team abstracted 36 IHAEs and grouped them into eight composite categories. The primary outcome was 90-day all-cause mortality, and secondary outcomes included length of stay (LOS), in-hospital mortality, and 90-day postdischarge all-cause readmission.

Results

Of the 11,169 hospitalized HF patients (median age 77.7 years; 47.0% women; 7.1% non-white; 39.8% from rural counties; 78,869 hospital bed-days), IHAEs occurred at varying frequency across the composite IHAE categories: general 4.6%, cardiovascular 6.6%, pulmonary 11.7%, endocrine and metabolism 9.2%, renal and electrolyte 9.1%, gastrointestinal 4.0%, neurological 2.7%, and hospital-acquired infection (HAI) 3.2%. Except for the renal and electrolyte (hazard ratio [HR] 0.92, p = 0.2956), IHAE in any other category was consistently associated with higher 90-day mortality (HRs 1.50-2.42, p < 0.0001 for all). Associations with secondary outcomes varied by IHAE categories: LOS increased in the general (incident rate ratio [IRR] 1.09), pulmonary (IRR 1.65), neurological (IRR 1.37), and HAI (IRR 1.09) categories (p < 0.0001). In-hospital mortality was higher in all categories except gastrointestinal. The 90-day readmission rate was elevated in the gastrointestinal (HR 1.85), neurological (HR 1.89), and HAI (HR 1.66) categories (p < 0.0001). Guideline-focused medical treatment (GFMT) was associated with reduced mortality in patients with and without IHAEs.

Conclusion

HF cohorts with specific composite IHAEs experience higher in-hospital and 90-day all-cause mortality and increased health care resource utilization. This elevated mortality risk may be mitigated by GFMT, with potential tailoring to each specific IHAE category.
背景:住院不良事件(IHAEs)是关键的患者安全指标,但在心力衰竭(HF)住院患者中尚未得到全面评估。作者旨在确定IHAEs与下游预后的关系。方法:本回顾性多中心队列研究分析了2010-2023年17家急症医院因心衰住院患者的资料。研究小组提取了36个IHAEs,并将它们分为8个复合类别。主要终点为90天全因死亡率,次要终点包括住院时间(LOS)、住院死亡率和出院后90天全因再入院。结果:11169例住院HF患者(中位年龄77.7岁;47.0%的女性;7.1%的白人;农村县占39.8%;78,869医院床位日),IHAEs在复合IHAEs类别中发生的频率不同:一般4.6%,心血管6.6%,肺部11.7%,内分泌和代谢9.2%,肾脏和电解质9.1%,胃肠道4.0%,神经系统2.7%,医院获得性感染(HAI) 3.2%。除了肾脏和电解质(危险比[HR] 0.92, p = 0.2956)外,任何其他类型的IHAE均与较高的90天死亡率相关(危险比1.50-2.42,p < 0.0001)。与次要结局的关联因IHAE类型而异:LOS在一般(发生率比[IRR] 1.09)、肺(IRR 1.65)、神经(IRR 1.37)和HAI (IRR 1.09)类别中增加(p < 0.0001)。除胃肠道外,所有类别的住院死亡率均较高。胃肠道(HR 1.85)、神经系统(HR 1.89)和HAI (HR 1.66)类别的90天再入院率均升高(p < 0.0001)。以指南为重点的药物治疗(GFMT)与伴有和不伴有IHAEs的患者死亡率降低相关。结论:具有特定复合IHAEs的心衰队列具有更高的住院死亡率和90天全因死亡率,并增加了医疗资源利用率。这种升高的死亡风险可以通过GFMT减轻,并可能针对每个特定的IHAE类别进行定制。
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引用次数: 0
System Strategies to Optimize the Critical Role of the Medical Interpreter 优化医学口译关键作用的系统策略。
IF 2.4 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-03-21 DOI: 10.1016/j.jcjq.2025.03.002
Kathy Sliwinski PhD, MBE, RN (is Post-Doctoral Fellow, Center for Health Services & Outcomes Research, Northwestern University Feinberg School of Medicine.), Eileen Johnson PhD, CTP (is Manager, Patient Relations & Interpretation Services, Northwestern Memorial Hospital, Chicago.), Ana Galli MD, MA (is Medical Interpreter, Northwestern Memorial Hospital), Victor Buzeta (is Medical Interpreter, Northwestern Memorial Hospital.), Cynthia Barnard PhD, MBA, MS (is Lecturer in Medicine and Medical Social Sciences, Northwestern University Feinberg School of Medicine. Please address correspondence to Kathy Sliwinski)
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引用次数: 0
Enhanced Antibiotic Stewardship Program's Effect on Antibiotic Stewardship in Four Thai Hospitals 加强抗生素管理计划对四家泰国医院抗生素管理的影响。
IF 2.3 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-03-05 DOI: 10.1016/j.jcjq.2025.03.001
Kittiya Jantarathaneewat PharmD, BCP, BCIDP (Research Group in Infectious Diseases Epidemiology and Prevention, Faculty of Medicine, and Center of Excellence in Pharmacy Practice and Management Research, Faculty of Pharmacy, Thammasat University, Pathum Thani, Thailand), Anucha Thatrimontrichai MD (Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand), Nattapol Pruetpongpun MD (Department of Medicine, Bangkok Phitsanulok Hospital, Phitsanulok, Thailand), Siriththin Chansirikarnjana MD (Division of Infectious Diseases, Lerdsin Hospital, Bangkok, Thailand), Sasinuch Rutjanawech MD (Research Group in Infectious Diseases Epidemiology and Prevention, Faculty of Medicine, and Division of Infectious Diseases, Faculty of Medicine, Thammasat University), David J. Weber MD, MPH (Gillings School of Global Public Health, University of North Carolina School of Medicine), Anucha Apisarnthanarak MD (Research Group in Infectious Diseases Epidemiology and Prevention, Faculty of Medicine, and Division of Infectious Diseases, Faculty of Medicine, Thammasat University. Please address correspondence to Anucha Apisarnthanarak)

Background

An antimicrobial stewardship program (ASP) is crucial for reducing inappropriate antimicrobial use, improving patient outcomes, and combating increasing antimicrobial resistance. However, data on the implementation of enhanced ASP networks in Asia are limited.

Methods

This quasi-experimental study evaluated an ASP collaborative network across four hospitals in Thailand (two university hospitals, a tertiary care center, and a private hospital) during 2021 and 2022. Baseline ASP activities were assessed using gap analysis surveys. Effectiveness was measured through antibiotic consumption (daily defined dose, [DDD] per 1,000 patient-days), appropriateness of antibiotic use, and the incidence of multidrug-resistant organisms (MDROs).

Results

The enhanced ASP network addressed key challenges, leading to significant improvements in ASP implementation. Notable achievements included an increase in the overall appropriateness of target antibiotic use (86.5% vs. 74.4 %, p < 0.05) and a reduction in target antibiotic consumptions in all hospitals. The incidence of MDROs, including carbapenem-resistant Acinetobacter baumannii (30.22 vs. 6.08 per 1,000 patient-days, p < 0.05) and methicillin-resistant Staphylococcus aureus (1.90 vs. 0.46 per 1,000 patient-days, p < 0.05), declined significantly in one hospital. The incidence of multidrug-resistant pathogens declined after the implementation of the enhanced ASP in two hospitals.

Conclusion

The enhanced networking program in this study significantly improved ASP implementation across diverse hospital settings in Thailand. It addressed challenges such as insufficient financial support. Notable improvements were observed in the appropriateness of antibiotic use and overall antibiotic consumption, potentially contributing to the reduction in multidrug-resistant pathogens. These findings highlight the effectiveness of a collaborative ASP network in Asia.
背景:抗菌药物管理计划(ASP)对于减少不适当的抗菌药物使用,改善患者预后和对抗日益增加的抗菌药物耐药性至关重要。然而,关于亚洲加强ASP网络实施情况的数据有限。方法:这项准实验研究评估了2021年和2022年期间泰国四家医院(两所大学医院、一家三级保健中心和一家私立医院)的ASP协作网络。基线ASP活动使用差距分析调查进行评估。通过抗生素用量(每日限定剂量,每1000患者日的DDD)、抗生素使用的适宜性和多重耐药菌(mdro)的发生率来衡量有效性。结果:增强的ASP网络解决了关键挑战,导致ASP实施方面的重大改进。值得注意的成果包括目标抗生素使用的总体适宜性增加(86.5%对74.4%,p < 0.05),所有医院的目标抗生素使用量减少。一家医院耐碳青霉烯鲍曼不动杆菌(30.22 vs. 6.08 / 1000患者-天,p < 0.05)和耐甲氧西林金黄色葡萄球菌(1.90 vs. 0.46 / 1000患者-天,p < 0.05)的MDROs发生率均显著下降。两家医院实施强化ASP后,耐多药病原菌的发病率有所下降。结论:本研究中增强的网络计划显著改善了泰国不同医院环境中ASP的实施。它解决了财政支持不足等挑战。在抗生素使用的适宜性和总体抗生素消费方面观察到显著的改善,可能有助于减少耐多药病原体。这些发现突出了合作ASP网络在亚洲的有效性。
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引用次数: 0
Patient Engagement in Safety: Are We There Yet? 患者参与安全:我们做到了吗?
IF 2.3 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-03-01 DOI: 10.1016/j.jcjq.2025.02.006
Tejal Gandhi MD MPH (is Chief Safety and Transformation Officer, Press Ganey Associates LLC), Urmimala Sarkar MD MPH (is Professor of Medicine, University of California, San Francisco)
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引用次数: 0
Overcoming Professional Silos and Threats to Psychological Safety: A Conceptual Framework for Successful Team-Based Morbidity and Mortality Conferences 克服专业竖井和心理安全的威胁:一个成功的基于团队的发病率和死亡率会议的概念框架。
IF 2.3 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-02-27 DOI: 10.1016/j.jcjq.2025.02.005
Brian A. Campos MD (is Safe Surgery/Safe Systems Fellow, Ariadne Labs, T.H. Chan School of Public Health, Boston, and General Surgery Resident PGY3, Department of Surgery, Beth Israel Deaconess Medical Center, Boston.), Mary E. Brindle MD, MPH (is Principal Research Scientist, Ariadne Labs, and Professor, Department of Surgery, Cumming School of Medicine, University of Calgary.), Emily Cummins PhD (is Senior Qualitative Specialist, Ariadne Labs.), Alexander Hannenberg MD (is Core Faculty Member, Safe Surgery/Safe Systems Program, Ariadne Labs, and Adjunct Clinical Professor, Department of Anesthesiology, Tufts University School of Medicine.), Danielle Salley MS, BSN, RN (is Manager, Department of Quality and Clinical Projects, Children's Memorial Hermann Hospital, Houston.), Yves Sonnay MSPH (is Assistant Director of Project Management, Safe Surgery/Safe Systems Program, Ariadne Labs.), Aubrey Samost-Williams MD, MS (is Associate Faculty Member, Ariadne Labs, and Assistant Professor, Department of Anesthesia, Critical Care and Pain Medicine, University of Texas Health Science Center, Houston. Please address correspondence to Brian A. Campos)

Background

Adverse events in health care are frequently discussed in morbidity and mortality conferences. However, while health care has evolved to be delivered by interprofessional teams, morbidity and mortality conferences have been slow to include all team members. One particularly potent barrier to conducting an interprofessional team–based morbidity and mortality conference is a lack of psychological safety among team members. Clinicians from various professions bring differences in perspectives, culture, perceived hierarchy, and assumptions about other professions. These perspectives may bring value to the interprofessional team–based morbidity and mortality conferences, but they may also degrade psychological safety.

Methods

This report explores the link between professional silos and psychological safety among the health care team in the context of an interprofessional team–based morbidity and mortality conference using the perioperative space as an example. The authors draw on the concept of team fault lines—a potential division along a team members' characteristics that can divide a group or team into subgroups. The roots of perioperative professional silos, which define these fault lines, are then traced to the historical context of the health care professions, the individual development of professional identities, and the role of organizations in maintaining these silos. From these observations, a framework for describing these foundations is proposed, which the authors use to evaluate the broader teamwork-in-health-care literature to generate specific recommendations to promote psychological safety in team-based morbidity and mortality conferences.

Conclusion

This framework can be used to postulate strategies for improving the ability for teams to learn from morbidity and mortality conferences. However, future work remains in implementing and studying these recommendations.
背景:在发病率和死亡率会议上经常讨论卫生保健中的不良事件。然而,虽然保健已演变为由跨专业团队提供,但发病率和死亡率会议却迟迟没有包括所有团队成员。举办跨专业团队发病率和死亡率会议的一个特别强大的障碍是团队成员之间缺乏心理安全感。来自不同职业的临床医生在观点、文化、感知等级和对其他职业的假设方面存在差异。这些观点可能为跨专业团队的发病率和死亡率会议带来价值,但它们也可能降低心理安全性。方法:本报告以围手术期病死率会议为例,探讨医疗团队中专业孤岛与心理安全之间的联系。作者借鉴了团队断层线的概念——沿着团队成员特征的潜在分裂,可以将一个团队或团队划分为子组。围手术期专业竖井的根源,定义了这些断层线,然后追溯到卫生保健专业的历史背景,专业身份的个人发展,以及组织在维持这些竖井中的作用。根据这些观察,提出了一个描述这些基础的框架,作者使用该框架来评估更广泛的医疗保健团队合作文献,以产生具体建议,以促进基于团队的发病率和死亡率会议的心理安全。结论:该框架可用于制定策略,提高团队从发病率和死亡率会议中学习的能力。但是,今后的工作仍是执行和研究这些建议。
{"title":"Overcoming Professional Silos and Threats to Psychological Safety: A Conceptual Framework for Successful Team-Based Morbidity and Mortality Conferences","authors":"Brian A. Campos MD (is Safe Surgery/Safe Systems Fellow, Ariadne Labs, T.H. Chan School of Public Health, Boston, and General Surgery Resident PGY3, Department of Surgery, Beth Israel Deaconess Medical Center, Boston.),&nbsp;Mary E. Brindle MD, MPH (is Principal Research Scientist, Ariadne Labs, and Professor, Department of Surgery, Cumming School of Medicine, University of Calgary.),&nbsp;Emily Cummins PhD (is Senior Qualitative Specialist, Ariadne Labs.),&nbsp;Alexander Hannenberg MD (is Core Faculty Member, Safe Surgery/Safe Systems Program, Ariadne Labs, and Adjunct Clinical Professor, Department of Anesthesiology, Tufts University School of Medicine.),&nbsp;Danielle Salley MS, BSN, RN (is Manager, Department of Quality and Clinical Projects, Children's Memorial Hermann Hospital, Houston.),&nbsp;Yves Sonnay MSPH (is Assistant Director of Project Management, Safe Surgery/Safe Systems Program, Ariadne Labs.),&nbsp;Aubrey Samost-Williams MD, MS (is Associate Faculty Member, Ariadne Labs, and Assistant Professor, Department of Anesthesia, Critical Care and Pain Medicine, University of Texas Health Science Center, Houston. Please address correspondence to Brian A. Campos)","doi":"10.1016/j.jcjq.2025.02.005","DOIUrl":"10.1016/j.jcjq.2025.02.005","url":null,"abstract":"<div><h3>Background</h3><div>Adverse events in health care are frequently discussed in morbidity and mortality conferences. However, while health care has evolved to be delivered by interprofessional teams, morbidity and mortality conferences have been slow to include all team members. One particularly potent barrier to conducting an interprofessional team–based morbidity and mortality conference is a lack of psychological safety among team members. Clinicians from various professions bring differences in perspectives, culture, perceived hierarchy, and assumptions about other professions. These perspectives may bring value to the interprofessional team–based morbidity and mortality conferences, but they may also degrade psychological safety.</div></div><div><h3>Methods</h3><div>This report explores the link between professional silos and psychological safety among the health care team in the context of an interprofessional team–based morbidity and mortality conference using the perioperative space as an example. The authors draw on the concept of team fault lines—a potential division along a team members' characteristics that can divide a group or team into subgroups. The roots of perioperative professional silos, which define these fault lines, are then traced to the historical context of the health care professions, the individual development of professional identities, and the role of organizations in maintaining these silos. From these observations, a framework for describing these foundations is proposed, which the authors use to evaluate the broader teamwork-in-health-care literature to generate specific recommendations to promote psychological safety in team-based morbidity and mortality conferences.</div></div><div><h3>Conclusion</h3><div>This framework can be used to postulate strategies for improving the ability for teams to learn from morbidity and mortality conferences. However, future work remains in implementing and studying these recommendations.</div></div>","PeriodicalId":14835,"journal":{"name":"Joint Commission journal on quality and patient safety","volume":"51 6","pages":"Pages 415-422"},"PeriodicalIF":2.3,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutrition Optimization in Early Dialysis 早期透析的营养优化
IF 2.3 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-02-20 DOI: 10.1016/j.jcjq.2025.02.004
Aditya A. Khanijo MBBS (is Research Fellow, Department of Medicine, Mayo Clinic, Jacksonville), Lorenzo Olivero MD (is Research Fellow, Department of Medicine, Mayo Clinic Jacksonville), Mireille H. Hamdan DCN, RDN, LD/N (is Clinical Nutrition Manager, Department of Nutrition Services, Mayo Clinic Jacksonville), Karen D. Stoner BSN, RN (is Nurse Manager, Critical Care, Mayo Clinic Jacksonville), Angela C. Majerus MHA (is Manager, Outpatient Practices Administration, Mayo Clinic Health System (Austin)), Dimple B. Patel RN (is Nurse Manager, Inpatient Dialysis, Mayo Clinic Jacksonville), Shannon Allen MHA (is Senior Patient Experience Advisor, Department of Quality, Mayo Clinic Jacksonville), Christopher L. Trautman MD (is Nephrologist, Department of Medicine, Mayo Clinic Jacksonville), Lisa M. Heath DNP, RN, NE-BC (is Nursing Quality Specialist, Nursing Administration, Mayo Clinic Jacksonville), Lindsay L. Meeusen MSN, RN, NPD-BC (is Nurse Manager, Nursing Administration, Mayo Clinic Rochester), C.J. Hemeyer APRN (is Nephrology Nurse Practitioner, Department of Medicine, Mayo Clinic Jacksonville), Steph R. Jenkins MSN, RN, CNL (is Nursing Team Leader, Division of Regional Medicine, Mayo Clinic Jacksonville), Pranvera Dautaj APRN (is Nephrology Nurse Practitioner, Department of Medicine, Mayo Clinic Jacksonville), Maria M. Rose MHA (is Associate Director, Department of Food Services, Mayo Clinic Jacksonville), Erlinda M. Flores RN (is Registered Nurse, Inpatient Dialysis, Mayo Clinic Jacksonville), MaQuita D. McGhee DNP, MSN, RN (is Nursing Education Specialist, Nursing Administration, Mayo Clinic Jacksonville), Pablo Moreno Franco MD (is Internist and Chair of Critical Care, Department of Transplantation, Mayo Clinic Jacksonville), Jennifer B. Cowart MD (is Internist and Chair of Quality, Department of Medicine, Mayo Clinic Jacksonville. Please address correspondence to Jennifer B. Cowart)

Background

Protein-energy wasting (PEW) syndrome is a common condition among patients suffering from end-stage renal disease (ESRD) receiving intermittent hemodialysis (IHD). Hospital nutrition barriers such as delayed meals and iatrogenic fasting can negatively affect patients’ experiences and contribute to long-standing nutritional deficits in at-risk patients. This project aimed to improve nutrition provision to inpatients with early IHD appointments by 50% (relative increase) without increasing IHD start time delays.

Methods

The Six Sigma DMAIC (Define, Measure, Analyze, Improve, and Control) methodology was used to guide the overall framework for process improvement, while specific improvements were implemented using Plan-Do-Study-Act (PDSA) cycles. Baseline data were analyzed for early morning appointments (5:00 a.m.–6:00 a.m.), and fishbone and Pareto charts were used to identify key barriers to nutrition availability. PDSA cycles were implemented to improve nutrition provision. Chi-square tests were conducted to assess significant changes in the percentage of patients reporting improved nutrition provision and reduced delays in dialysis start times.

Results

Baseline data showed that 38.6% of early IHD patients with diet orders at one tertiary care center received breakfast prior to their appointment. Stakeholder analysis and Pareto charts revealed that the mismatch between IHD start times and early meal tray delivery was a root cause. The first PDSA cycle adjusted nursing workflows, substituting early meals with bento snack boxes, achieving 54.2% nutrition provision. Following patient feedback, protein shakes were added, increasing provision to 93.8%. IHD start time delays decreased from 24.6% at baseline to an average of 10.2%, with these improvements sustained beyond 30 days postintervention.

Conclusion

The use of quality improvement methodology effectively improved nutrition delivery for high-risk patients and was associated with reduced hemodialysis start time delays and enhanced organizational efficiency. This project addressed a specific concern relating to patients receiving dialysis due to baseline rates of undernutrition and barriers to providing nourishment in the hospital. Future studies should focus on further analysis of patients on dialysis and expand to include other hospitalized subpopulations at risk for undernutrition, to optimize and generalize these interventions more broadly.
背景:蛋白质-能量消耗(PEW)综合征是接受间歇血液透析(IHD)的终末期肾病(ESRD)患者的常见症状。医院营养障碍,如延迟用餐和医源性禁食,会对患者的经历产生负面影响,并导致高危患者长期营养不足。该项目旨在在不增加IHD开始时间延迟的情况下,将IHD早期预约住院患者的营养供应提高50%(相对增加)。方法:使用六西格玛DMAIC(定义、测量、分析、改进和控制)方法来指导过程改进的总体框架,同时使用计划-执行-研究-行动(PDSA)循环实施具体改进。分析了清晨预约(上午5点至6点)的基线数据,并使用鱼骨图和帕累托图来确定营养可用性的主要障碍。实施PDSA循环以改善营养供应。进行卡方检验以评估报告营养供应改善和透析开始时间延迟减少的患者百分比的显著变化。结果:基线数据显示,38.6%的IHD早期患者在三级保健中心接受了饮食命令,在预约前吃了早餐。利益相关者分析和帕累托图显示,IHD开始时间和提前送餐之间的不匹配是根本原因。第一个PDSA周期调整了护理工作流程,用便当零食盒代替早餐,实现了54.2%的营养供应。根据患者的反馈,添加蛋白奶昔,使供给量增加到93.8%。IHD启动时间延迟从基线时的24.6%下降到平均10.2%,这些改善持续到干预后30天。结论:质量改进方法的使用有效地改善了高危患者的营养输送,并与减少血液透析开始时间延迟和提高组织效率相关。该项目解决了由于营养不良的基线率和在医院提供营养的障碍而与接受透析的患者有关的一个具体问题。未来的研究应侧重于对透析患者的进一步分析,并扩大到包括其他有营养不良风险的住院亚群,以更广泛地优化和推广这些干预措施。
{"title":"Nutrition Optimization in Early Dialysis","authors":"Aditya A. Khanijo MBBS (is Research Fellow, Department of Medicine, Mayo Clinic, Jacksonville),&nbsp;Lorenzo Olivero MD (is Research Fellow, Department of Medicine, Mayo Clinic Jacksonville),&nbsp;Mireille H. Hamdan DCN, RDN, LD/N (is Clinical Nutrition Manager, Department of Nutrition Services, Mayo Clinic Jacksonville),&nbsp;Karen D. Stoner BSN, RN (is Nurse Manager, Critical Care, Mayo Clinic Jacksonville),&nbsp;Angela C. Majerus MHA (is Manager, Outpatient Practices Administration, Mayo Clinic Health System (Austin)),&nbsp;Dimple B. Patel RN (is Nurse Manager, Inpatient Dialysis, Mayo Clinic Jacksonville),&nbsp;Shannon Allen MHA (is Senior Patient Experience Advisor, Department of Quality, Mayo Clinic Jacksonville),&nbsp;Christopher L. Trautman MD (is Nephrologist, Department of Medicine, Mayo Clinic Jacksonville),&nbsp;Lisa M. Heath DNP, RN, NE-BC (is Nursing Quality Specialist, Nursing Administration, Mayo Clinic Jacksonville),&nbsp;Lindsay L. Meeusen MSN, RN, NPD-BC (is Nurse Manager, Nursing Administration, Mayo Clinic Rochester),&nbsp;C.J. Hemeyer APRN (is Nephrology Nurse Practitioner, Department of Medicine, Mayo Clinic Jacksonville),&nbsp;Steph R. Jenkins MSN, RN, CNL (is Nursing Team Leader, Division of Regional Medicine, Mayo Clinic Jacksonville),&nbsp;Pranvera Dautaj APRN (is Nephrology Nurse Practitioner, Department of Medicine, Mayo Clinic Jacksonville),&nbsp;Maria M. Rose MHA (is Associate Director, Department of Food Services, Mayo Clinic Jacksonville),&nbsp;Erlinda M. Flores RN (is Registered Nurse, Inpatient Dialysis, Mayo Clinic Jacksonville),&nbsp;MaQuita D. McGhee DNP, MSN, RN (is Nursing Education Specialist, Nursing Administration, Mayo Clinic Jacksonville),&nbsp;Pablo Moreno Franco MD (is Internist and Chair of Critical Care, Department of Transplantation, Mayo Clinic Jacksonville),&nbsp;Jennifer B. Cowart MD (is Internist and Chair of Quality, Department of Medicine, Mayo Clinic Jacksonville. Please address correspondence to Jennifer B. Cowart)","doi":"10.1016/j.jcjq.2025.02.004","DOIUrl":"10.1016/j.jcjq.2025.02.004","url":null,"abstract":"<div><h3>Background</h3><div>Protein-energy wasting (PEW) syndrome is a common condition among patients suffering from end-stage renal disease (ESRD) receiving intermittent hemodialysis (IHD). Hospital nutrition barriers such as delayed meals and iatrogenic fasting can negatively affect patients’ experiences and contribute to long-standing nutritional deficits in at-risk patients. This project aimed to improve nutrition provision to inpatients with early IHD appointments by 50% (relative increase) without increasing IHD start time delays.</div></div><div><h3>Methods</h3><div>The Six Sigma DMAIC (Define, Measure, Analyze, Improve, and Control) methodology was used to guide the overall framework for process improvement, while specific improvements were implemented using Plan-Do-Study-Act (PDSA) cycles. Baseline data were analyzed for early morning appointments (5:00 <span>a.m.</span>–6:00 <span>a.m.</span>), and fishbone and Pareto charts were used to identify key barriers to nutrition availability. PDSA cycles were implemented to improve nutrition provision. Chi-square tests were conducted to assess significant changes in the percentage of patients reporting improved nutrition provision and reduced delays in dialysis start times.</div></div><div><h3>Results</h3><div>Baseline data showed that 38.6% of early IHD patients with diet orders at one tertiary care center received breakfast prior to their appointment. Stakeholder analysis and Pareto charts revealed that the mismatch between IHD start times and early meal tray delivery was a root cause. The first PDSA cycle adjusted nursing workflows, substituting early meals with bento snack boxes, achieving 54.2% nutrition provision. Following patient feedback, protein shakes were added, increasing provision to 93.8%. IHD start time delays decreased from 24.6% at baseline to an average of 10.2%, with these improvements sustained beyond 30 days postintervention.</div></div><div><h3>Conclusion</h3><div>The use of quality improvement methodology effectively improved nutrition delivery for high-risk patients and was associated with reduced hemodialysis start time delays and enhanced organizational efficiency. This project addressed a specific concern relating to patients receiving dialysis due to baseline rates of undernutrition and barriers to providing nourishment in the hospital. Future studies should focus on further analysis of patients on dialysis and expand to include other hospitalized subpopulations at risk for undernutrition, to optimize and generalize these interventions more broadly.</div></div>","PeriodicalId":14835,"journal":{"name":"Joint Commission journal on quality and patient safety","volume":"51 6","pages":"Pages 389-397"},"PeriodicalIF":2.3,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modeling Incremental Benefit of Medication Reconciliation on ICU Outcomes 药物调节对ICU预后的增量效益建模。
IF 2.3 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-02-19 DOI: 10.1016/j.jcjq.2025.02.001
Helen A. Harris MS (is Doctoral Candidate in Systems Modeling and Analysis, Department of Mathematics and Applied Mathematics, Virginia Commonwealth University (VCU)), David M. Chan PhD (is Professor, Department of Mathematics and Applied Mathematics, VCU), Laura Ellwein Fix PhD (is Associate Professor, Department of Mathematics and Applied Mathematics, VCU), Melissa Chouinard MD (is Director, Medication Safety, VCU Health, Richmond, Virginia, and Associate Professor, Division of Hospital Medicine, Department of Internal Medicine, VCU), Teresa M. Salgado MPharm, PhD (is Director, Center for Pharmacy Practice Innovation, VCU School of Pharmacy, and Associate Professor, Department of Pharmacotherapy and Outcomes Science, VCU), Le Kang PhD (is Associate Professor, Department of Biostatistics, School of Public Health, VCU), Gonzalo Bearman MD, MPH (is Professor, Department of Internal Medicine, and Chief, Division of Infectious Diseases, VCU. Please address correspondence to Helen Harris)

Background

Medication errors such as medication discrepancies can occur in patients who are hospitalized and may result in adverse drug events (ADEs). Pharmacist-led medication reconciliation (MR) is an intervention that can be used to address medication discrepancies. Estimating the impact of MR in a medical setting is challenging to do experimentally. In this study, researchers implemented a mathematical model for estimating impact.

Methods

The authors modeled the effects of a series of incremental changes in MR completion on ADEs and conducted a cost-effectiveness analysis using a Markov chain model.

Results

In a 28-bed ICU, increasing the MR completion rate resulted in decreases in the total number of yearly ADEs by as many as 106, varying by the baseline ADE rate. The financial implications of increasing MR completion ranged from $27,808 in additional costs to $1,818,440 in savings on a yearly basis, depending on the baseline ADE rate and cost per ADE.

Conclusion

For institutions with low ADE rates, as MR completion increases and ADEs decrease, MR (though clinically beneficial) may not be financially worthwhile. However, MR implementation was found to produce significant savings for hospitals with average or high ADE rates.
背景:住院患者可能会出现用药错误(如用药差异),并可能导致药物不良事件(ADE)。药剂师主导的用药调和(MR)是一种可用于解决用药差异的干预措施。通过实验来估计 MR 在医疗环境中的影响具有挑战性。在这项研究中,研究人员采用了一个数学模型来估算其影响:作者模拟了 MR 完成度的一系列递增变化对 ADE 的影响,并使用马尔科夫链模型进行了成本效益分析:结果:在一个拥有 28 张床位的重症监护病房中,提高 MR 完成率可使每年的 ADE 总数减少 106 例之多,具体因 ADE 基准率而异。根据基线 ADE 率和每例 ADE 成本的不同,提高 MR 完成率的财务影响从每年增加 27,808 美元的成本到节省 1,818,440 美元不等:结论:对于 ADE 发生率较低的医疗机构而言,随着 MR 完成率的提高和 ADE 的减少,MR(尽管对临床有益)在经济上可能并不划算。然而,对于 ADE 发生率处于平均水平或较高水平的医院而言,实施 MR 可节省大量资金。
{"title":"Modeling Incremental Benefit of Medication Reconciliation on ICU Outcomes","authors":"Helen A. Harris MS (is Doctoral Candidate in Systems Modeling and Analysis, Department of Mathematics and Applied Mathematics, Virginia Commonwealth University (VCU)),&nbsp;David M. Chan PhD (is Professor, Department of Mathematics and Applied Mathematics, VCU),&nbsp;Laura Ellwein Fix PhD (is Associate Professor, Department of Mathematics and Applied Mathematics, VCU),&nbsp;Melissa Chouinard MD (is Director, Medication Safety, VCU Health, Richmond, Virginia, and Associate Professor, Division of Hospital Medicine, Department of Internal Medicine, VCU),&nbsp;Teresa M. Salgado MPharm, PhD (is Director, Center for Pharmacy Practice Innovation, VCU School of Pharmacy, and Associate Professor, Department of Pharmacotherapy and Outcomes Science, VCU),&nbsp;Le Kang PhD (is Associate Professor, Department of Biostatistics, School of Public Health, VCU),&nbsp;Gonzalo Bearman MD, MPH (is Professor, Department of Internal Medicine, and Chief, Division of Infectious Diseases, VCU. Please address correspondence to Helen Harris)","doi":"10.1016/j.jcjq.2025.02.001","DOIUrl":"10.1016/j.jcjq.2025.02.001","url":null,"abstract":"<div><h3>Background</h3><div>Medication errors such as medication discrepancies can occur in patients who are hospitalized and may result in adverse drug events (ADEs). Pharmacist-led medication reconciliation (MR) is an intervention that can be used to address medication discrepancies. Estimating the impact of MR in a medical setting is challenging to do experimentally. In this study, researchers implemented a mathematical model for estimating impact.</div></div><div><h3>Methods</h3><div>The authors modeled the effects of a series of incremental changes in MR completion on ADEs and conducted a cost-effectiveness analysis using a Markov chain model.</div></div><div><h3>Results</h3><div>In a 28-bed ICU, increasing the MR completion rate resulted in decreases in the total number of yearly ADEs by as many as 106, varying by the baseline ADE rate. The financial implications of increasing MR completion ranged from $27,808 in additional costs to $1,818,440 in savings on a yearly basis, depending on the baseline ADE rate and cost per ADE.</div></div><div><h3>Conclusion</h3><div>For institutions with low ADE rates, as MR completion increases and ADEs decrease, MR (though clinically beneficial) may not be financially worthwhile. However, MR implementation was found to produce significant savings for hospitals with average or high ADE rates.</div></div>","PeriodicalId":14835,"journal":{"name":"Joint Commission journal on quality and patient safety","volume":"51 6","pages":"Pages 398-404"},"PeriodicalIF":2.3,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leveraging Approaches and Tools of Implementation Science and Configurational Comparative Methods in Quality Improvement 利用实施科学和配置比较方法在质量改进中的方法和工具
IF 2.3 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-02-14 DOI: 10.1016/j.jcjq.2025.02.003
Gabrielle Matias MD (Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL), Nandita R. Nadig MD, MSCR, ATSF (Division of Research and Optimal Patient Care, American College of Surgeons, Chicago, IL), Reiping Huang PhD (Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, Please address correspondence to Reiping Huang)
{"title":"Leveraging Approaches and Tools of Implementation Science and Configurational Comparative Methods in Quality Improvement","authors":"Gabrielle Matias MD (Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL),&nbsp;Nandita R. Nadig MD, MSCR, ATSF (Division of Research and Optimal Patient Care, American College of Surgeons, Chicago, IL),&nbsp;Reiping Huang PhD (Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, Please address correspondence to Reiping Huang)","doi":"10.1016/j.jcjq.2025.02.003","DOIUrl":"10.1016/j.jcjq.2025.02.003","url":null,"abstract":"","PeriodicalId":14835,"journal":{"name":"Joint Commission journal on quality and patient safety","volume":"51 4","pages":"Pages 239-240"},"PeriodicalIF":2.3,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143704883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient Safety Event Risk and Language Barriers: A Scoping Review 患者安全事件风险和语言障碍:范围综述。
IF 2.3 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-02-13 DOI: 10.1016/j.jcjq.2025.02.002
Lucy B. Schulson MD, MPH (is Assistant Professor, Section of General Internal Medicine, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine.), Jorge A. Rodriguez MD (is Research and Hospitalist, Division of General Internal Medicine, Brigham and Women's Hospital, Boston, and Assistant Professor, Harvard Medical School.), Ricardo Cruz MD, MPH, MA (is Assistant Professor, Section of General Internal Medicine, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine.), David Flynn MS (is Assistant Professor, Department of Medical Sciences & Education, Boston Medical Center, Boston University Chobanian & Avedisian School of Medicine.), Alicia Fernandez MD (is Professor, Department of Medicine, School of Medicine, University of California, San Francisco. Please address correspondence to Lucy B. Schulson)
Patients who experience language barriers (LBs) may be at risk for patient safety events (PSEs). We conducted a scoping review of the literature to understand the risk for and type of PSEs in those who experience LBs. We searched PubMed, Web of Science, and Embase in October 2023. The search was organized into the following concepts: language barriers and patient safety. We included English language studies where risk of a PSE was compared in patients who experience to those who do not experience LBs or where types/characteristics of PSEs were compared in patients who are and are not at risk for LBs. We identified 22 studies for inclusion. Studies were primarily based in the United States and inpatient focused. Multiple methods were used to define patients who experience LBs and to identify PSEs. Patients who experienced LBs appeared to be at risk for communication-sensitive safety events, including medication-related adverse events and events related to vaginal deliveries, but at equal or lower risk for other types of events. Studies that did not rely solely on PSEs identified by clinician/staff report were more likely to identify disparities. We found few studies on PSE risk and LBs, a reflection of the dearth of research in this area and data sources with patient language. Studies had mixed results in part due to the multiple methods used to identify patients who experience LBs and PSEs. Interventions to reduce PSEs for patients who experience LBs should focus on events resulting from communication breakdowns.
经历语言障碍(LBs)的患者可能面临患者安全事件(pse)的风险。我们对文献进行了范围审查,以了解那些经历过LBs的人发生pse的风险和类型。我们在2023年10月检索了PubMed, Web of Science和Embase。搜索被组织成以下概念:语言障碍和患者安全。我们纳入了英语语言研究,其中比较了经历过LBs的患者和没有经历过LBs的患者的PSE风险,或者比较了有LBs风险和没有LBs风险的患者的PSE类型/特征。我们确定了22项研究纳入。研究主要以美国为基础,以住院病人为重点。使用多种方法来定义经历LBs的患者并识别pse。经历过LBs的患者似乎面临着通信敏感安全事件的风险,包括与药物相关的不良事件和与阴道分娩相关的事件,但其他类型事件的风险相同或更低。不完全依赖临床医生/工作人员报告确定的pse的研究更有可能发现差异。我们发现很少有关于PSE风险和LBs的研究,这反映了该领域研究和患者语言数据源的缺乏。研究结果好坏参半,部分原因是使用了多种方法来识别经历过LBs和pse的患者。对于经历LBs的患者,减少pse的干预措施应侧重于沟通中断导致的事件。
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引用次数: 0
The Scholarly Upside to MOC4 MOC4的学术优势。
IF 2.3 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-02-01 DOI: 10.1016/j.jcjq.2024.10.014
Glenn Seela (is a Medical Student, University of Minnesota Medical School.), David Satin MD (is an Associate Professor, Department of Family Medicine and Community Health, University of Minnesota Medical School, and Affiliate Faculty Center for Bioethics, University of Minnesota.), Cathy Centola (is Division Administrator, Department of Pediatrics, University of Minnesota Medical School.), Sameer Gupta MD, MBA (is an Associate Professor, Department of Pediatrics, University of Minnesota Medical School.), Paul Hodges MPP (is Director of Process Improvement and Clinical Quality, M Health Fairview, University of Minnesota Medical Center.), Jeff Louie MD (is an Associate Professor, Department of Pediatrics, University of Minnesota Medical School.), Tanya E. Melnik MD, MS (is an Associate Professor, Department of Medicine, University of Minnesota Medical School.), David Pelletier MSE, ICBB (is Principal Consultant, Quality Improvement, M Health Fairview.), Christina Russell MD (is an Assistant Professor, Department of Pediatrics, University of Minnesota Medical School.), Andrew Thompson MBA, MBB (Principal Consultant, Performance Improvement, M Health Fairview.), Jordan Marmet MD (is an Associate Professor, Department of Pediatrics, University of Minnesota Medical School. Please address correspondence to Jordan Marmet)

Background

Many medical boards require quality improvement (QI) projects for Maintenance of Certification Part IV (MOC4) credits. The American Board of Medical Specialties (ABMS) allows health care organizations that can demonstrate sufficient QI standards to become Portfolio Program Sponsors. This enables internal review and approval of QI projects, crediting all sufficiently contributing physicians. The University of Minnesota's M Health Fairview MOC4 Review Board (MMRB) was approved as an ABMS Portfolio Program Sponsor; the impact was surveyed from inception in 2016 to 2022. The objective was to examine the impact of a Portfolio Sponsor program on scholarship, sustainability, and spread of QI projects.

Methods

The authors developed and validated an eight-question survey directed at MOC4 principal investigators (PIs) who were awarded credits through the MMRB from 2016 to 2022. Participants reported on numbers of peer-reviewed publication or presentation, and their perception of increased preparedness for scholarship due to the application process. They also reported on sustainment or spread following their original QI project.

Results

Fifty projects were reviewed over a seven-year span. Of these, 44 were approved as demonstrating sufficient QI rigor per ABMS standards. Of 41 PIs, 27 (65.9%) responded to the survey; 15 (55.6%) agreed that the MMRB process helped prepare them for scholarly dissemination, 19 (70.4%) delivered oral or poster presentations, and 10 (37.0%) submitted a total of 14 manuscripts for publication, 10 of which were accepted. A total of 23 QI projects (85.2%) were sustained, and 10 (37.0%) had spread.

Conclusion

In addition to generating essential MOC4 credits for participating physicians, an MMRB process can help PIs prepare for scholarship, project sustainment, and spread.
背景:许多医学委员会要求质量改进(QI)项目来维护认证第四部分(MOC4)学分。美国医学专业委员会(ABMS)允许能够证明足够的QI标准的卫生保健组织成为投资组合计划的赞助商。这使得QI项目能够进行内部审查和批准,并将所有充分贡献的医生归功于自己。明尼苏达大学M Health Fairview MOC4审查委员会(MMRB)被批准为ABMS投资组合项目赞助商;从2016年开始到2022年,对其影响进行了调查。目的是检查投资组合赞助计划对奖学金、可持续性和QI项目传播的影响。方法:作者开发并验证了一项针对2016年至2022年通过MMRB获得学分的MOC4首席研究员(pi)的8个问题调查。参与者报告了同行评审的出版物或演讲的数量,以及他们对申请过程提高奖学金准备程度的看法。他们还报告了原始QI项目之后的维持或传播情况。结果:在7年的时间里对50个项目进行了审查。其中,44个被批准为证明了足够的符合ABMS标准的QI严格性。41个pi中,27个(65.9%)回应了调查;15人(55.6%)认为MMRB过程帮助他们为学术传播做好了准备,19人(70.4%)进行了口头或海报演讲,10人(37.0%)提交了14篇论文供发表,其中10篇被接受。共有23个项目(85.2%)得到维持,10个项目(37.0%)得到扩展。结论:除了为参与项目的医生产生必要的MOC4学分外,MMRB流程还可以帮助pi为奖学金、项目维持和推广做好准备。
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引用次数: 0
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Joint Commission journal on quality and patient safety
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