Pub Date : 2022-01-01DOI: 10.1177/22808000221087349
Abdullah S Aljamhan, Mohammad H Alrefeai, Alhanouf Alhabdan, Mona H Alzehiri, Mustafa Naseem, Fahim Vohra, Fahad Alkhudhairy
The aim was to prepare experimental adhesive (EA) with ZrO2 nanoparticles (ZEA) and without it; and its interaction with dentin conditioned with photodynamic therapy (PDT), etch and rinse, and Er, Cr: YSGG laser (ECL). Methods consisted of the scanning electron microscope (SEM), energy dispersive X-ray (EDX), shear bond strength (SBS) failure mode, and rheological property analysis. The methods were employed to assess bond integrity; the shape of ZrO2 NPs and interfacial dentin and adhesive interaction. Ninety premolar teeth were collected and pre-bonding, conditioning of dentin was performed utilizing phosphoric acid (H3PO4), photodynamic therapy (PDT), and ER-CR-YSGG laser (ECL). The teeth were set to form bonded specimens using two adhesives EA and ZEA. The microscopic imagery of ZrO2 revealed irregular-shaped, non-edged particles. EDX analysis revealed Zr to be 75.7% whereas, O2 by weight was 25.3%. The highest SBS was demonstrated in dentin conditioned with etch and rinse and ZEA (19.05 ± 0.13 MPa). Whereas, the lowest SBS was observed in dentin surface treated with PDT and EA (12.25 ± 0.14 MPa). Most of the reported failure modes were adhesive. Rheological analysis revealed that with increasing frequencies the viscosities of adhesives were reduced. The presence of 10% ZrO by weight in adhesive improves SBS of restoration and this improvement in bond values is statistically significant compared to EA. Bond values may be influenced by surface treatment of dentin.
{"title":"Interaction of zirconium oxide nanoparticle infiltrated resin adhesive with dentin conditioned by phosphoric acid and Er, Cr: YSGG laser.","authors":"Abdullah S Aljamhan, Mohammad H Alrefeai, Alhanouf Alhabdan, Mona H Alzehiri, Mustafa Naseem, Fahim Vohra, Fahad Alkhudhairy","doi":"10.1177/22808000221087349","DOIUrl":"https://doi.org/10.1177/22808000221087349","url":null,"abstract":"<p><p>The aim was to prepare experimental adhesive (EA) with ZrO<sub>2</sub> nanoparticles (ZEA) and without it; and its interaction with dentin conditioned with photodynamic therapy (PDT), etch and rinse, and Er, Cr: YSGG laser (ECL). Methods consisted of the scanning electron microscope (SEM), energy dispersive X-ray (EDX), shear bond strength (SBS) failure mode, and rheological property analysis. The methods were employed to assess bond integrity; the shape of ZrO<sub>2</sub> NPs and interfacial dentin and adhesive interaction. Ninety premolar teeth were collected and pre-bonding, conditioning of dentin was performed utilizing phosphoric acid (H3PO4), photodynamic therapy (PDT), and ER-CR-YSGG laser (ECL). The teeth were set to form bonded specimens using two adhesives EA and ZEA. The microscopic imagery of ZrO<sub>2</sub> revealed irregular-shaped, non-edged particles. EDX analysis revealed Zr to be 75.7% whereas, O2 by weight was 25.3%. The highest SBS was demonstrated in dentin conditioned with etch and rinse and ZEA (19.05 ± 0.13 MPa). Whereas, the lowest SBS was observed in dentin surface treated with PDT and EA (12.25 ± 0.14 MPa). Most of the reported failure modes were adhesive. Rheological analysis revealed that with increasing frequencies the viscosities of adhesives were reduced. The presence of 10% ZrO by weight in adhesive improves SBS of restoration and this improvement in bond values is statistically significant compared to EA. Bond values may be influenced by surface treatment of dentin.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":"20 ","pages":"22808000221087349"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10344763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Polysilicon wire (PSW) sensor with a sensing membrane of 3-aminopropyltrimethylsiloxan (γ-APTES) incorporated with polydimethylsiloxane (PDMS)-treated silica nanoparticles (NPs) (γ-APTES+NPs nanocomposite) deposited by a focus ion beam (FIB)-milled capillary atomic force microscopy (AFM) tip have been reported to have excellent biochemical sensing characteristics, and improved performance can be achieved after the sensing films being subjected to ultraviolet (UV) light illumination. While most of the research on γ-APTES is focused on its sensing characteristics and material properties, rarely have been discussed regarding its electrical characteristics. In this work, nanoscale current-voltage (I-V) characteristics of the FIB-milled capillary AFM tip deposited pure γ-APTES film and γ-APTES+NPs nanocomposite films with different γ-APTES/NPs mixed ratios were measured by using an AFM with a conductive tip as the top electrode. The I-V characteristics of the γ-APTES and γ-APTES+NPs films after UV illumination were also investigated. Our experimental results show that the nanoscale I-V curve of the γ-APTES-based films is similar to that of a typical dielectric film, and the nanoscale bulk leakage current decreases with the increase of the UV exposure time and the γ-APTES solution/NPs mixed ratios, while the breakdown voltage increases with increasing UV exposure time but decreases with the increase of γ-APTES solution/NPs mixed ratios.
{"title":"Ultraviolet Light Exposure Effect on the Nanoscale Current-Voltage Characteristics of Bare and Silicate Nanoparticle Incorporated 3-aminopropyltrimethylsiloxane Films Deposited Using a Focus Ion Beam-Milled Atomic Force Microscopy Tip","authors":"Su-Yu Liao, Jheng-Jia Jhuang, Jing-Jenn Lin, Congo Tak-Shing Ching, You-Lin Wu","doi":"10.35745/afm2021v01.01.0005","DOIUrl":"https://doi.org/10.35745/afm2021v01.01.0005","url":null,"abstract":"Polysilicon wire (PSW) sensor with a sensing membrane of 3-aminopropyltrimethylsiloxan (γ-APTES) incorporated with polydimethylsiloxane (PDMS)-treated silica nanoparticles (NPs) (γ-APTES+NPs nanocomposite) deposited by a focus ion beam (FIB)-milled capillary atomic force microscopy (AFM) tip have been reported to have excellent biochemical sensing characteristics, and improved performance can be achieved after the sensing films being subjected to ultraviolet (UV) light illumination. While most of the research on γ-APTES is focused on its sensing characteristics and material properties, rarely have been discussed regarding its electrical characteristics. In this work, nanoscale current-voltage (I-V) characteristics of the FIB-milled capillary AFM tip deposited pure γ-APTES film and γ-APTES+NPs nanocomposite films with different γ-APTES/NPs mixed ratios were measured by using an AFM with a conductive tip as the top electrode. The I-V characteristics of the γ-APTES and γ-APTES+NPs films after UV illumination were also investigated. Our experimental results show that the nanoscale I-V curve of the γ-APTES-based films is similar to that of a typical dielectric film, and the nanoscale bulk leakage current decreases with the increase of the UV exposure time and the γ-APTES solution/NPs mixed ratios, while the breakdown voltage increases with increasing UV exposure time but decreases with the increase of γ-APTES solution/NPs mixed ratios.","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":"14 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78843394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-30DOI: 10.35745/afm2021v01.01.0007
Chingfu Wang, Fang-Hsing Wang, Han-Wen Liu
In this study, we investigated a novel technology to grow the ZnO nanoflower arrays on a patterned sapphire substrate using hydrothermal method. The process to prepare the substrate and grow ZnO nanoflower arrays were that the patterned concave sapphire substrates were cleaned using acetone, isopropyl alcohol, and D.I. water in an ultrasonic cleaner. Al sacrificial layer with the thickness of 600 nm was deposited using a thermal evaporation technology. The sol-gel process was used to deposit the ZnO seed layer on the patterned concave sapphire substrates, and then the ZnO seed layer was annealed at 500°C in Ar ambient for 1 h. The optical grade silicone A-B glue was coated on the ZnO seed layer and then the mixed solution of K3Fe(CN)6 : KOH : H2O = 10 g : 1 g : 100 ml was used to etch the sacrificial Al layer. (f) A lift-off technology was used to move the ZnO seed layer/silicone A-B glue to silicon substrate. Finally, a hydrothermal method was used to grow the ZnO nanorods on the ZnO seed layer/silicone A-B glue/silicon substrate at 90oC with the different durations of 10 to 60 min. Focused ion beam system (FIB) was used to observe the cross sectional morphology of patterned ZnO seed layer. The crystal structural of the flower-like ZnO nanostructures was analyzed using X-ray diffraction (XRD) pattern, the morphological of the flower-like ZnO nanostructures was observed using FIB and field emission scanning electron microscope (FESEM). Also, the optical properties of the flower-like ZnO nanostructures were investigated.
{"title":"Growth of ZnO Nanoflower Arrays on a Patterned Sapphire Substrate","authors":"Chingfu Wang, Fang-Hsing Wang, Han-Wen Liu","doi":"10.35745/afm2021v01.01.0007","DOIUrl":"https://doi.org/10.35745/afm2021v01.01.0007","url":null,"abstract":"In this study, we investigated a novel technology to grow the ZnO nanoflower arrays on a patterned sapphire substrate using hydrothermal method. The process to prepare the substrate and grow ZnO nanoflower arrays were that the patterned concave sapphire substrates were cleaned using acetone, isopropyl alcohol, and D.I. water in an ultrasonic cleaner. Al sacrificial layer with the thickness of 600 nm was deposited using a thermal evaporation technology. The sol-gel process was used to deposit the ZnO seed layer on the patterned concave sapphire substrates, and then the ZnO seed layer was annealed at 500°C in Ar ambient for 1 h. The optical grade silicone A-B glue was coated on the ZnO seed layer and then the mixed solution of K3Fe(CN)6 : KOH : H2O = 10 g : 1 g : 100 ml was used to etch the sacrificial Al layer. (f) A lift-off technology was used to move the ZnO seed layer/silicone A-B glue to silicon substrate. Finally, a hydrothermal method was used to grow the ZnO nanorods on the ZnO seed layer/silicone A-B glue/silicon substrate at 90oC with the different durations of 10 to 60 min. Focused ion beam system (FIB) was used to observe the cross sectional morphology of patterned ZnO seed layer. The crystal structural of the flower-like ZnO nanostructures was analyzed using X-ray diffraction (XRD) pattern, the morphological of the flower-like ZnO nanostructures was observed using FIB and field emission scanning electron microscope (FESEM). Also, the optical properties of the flower-like ZnO nanostructures were investigated.","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":"74 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80491372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Graphene has attracted a lot of attention in gas sensing applications for its high surface area ratio and unique chemical or physical gas adsorption ability. Being an important research method, theoretical calculations play a key role in both illustrating the gas sensing mechanism of graphene and improving the gas sensing performance of graphene-based sensors. This review discusses the application of adsorption isotherm theory and first-principles studies to graphene gas sensors. Different isotherm theories are presented, including Langmuir, Freundlich, BET, and Temkin isotherm models, and it is illustrated how to investigate the adsorption information from them. The first-principles analysis of graphene-based gas sensors is presented. In general, doping with transition metals and nonmetals can improve the sensitivity of graphene to gases. This review shows the significance of using theoretical calculations to design novel and efficient gas sensors. The theoretical results obtained so far can be of great help in designing novel and efficient graphene-based gas sensors.
{"title":"Isotherm Models and First-Principles Studies of Gas Adsorption in Graphene Field-Effect Transistors: A Review","authors":"Chenrong Gong, Ran Wang, Jia Liu, Xianjie Wan, Zhou Yu, Weihua Liu, Guohe Zhang","doi":"10.35745/afm2021v01.01.0006","DOIUrl":"https://doi.org/10.35745/afm2021v01.01.0006","url":null,"abstract":"Graphene has attracted a lot of attention in gas sensing applications for its high surface area ratio and unique chemical or physical gas adsorption ability. Being an important research method, theoretical calculations play a key role in both illustrating the gas sensing mechanism of graphene and improving the gas sensing performance of graphene-based sensors. This review discusses the application of adsorption isotherm theory and first-principles studies to graphene gas sensors. Different isotherm theories are presented, including Langmuir, Freundlich, BET, and Temkin isotherm models, and it is illustrated how to investigate the adsorption information from them. The first-principles analysis of graphene-based gas sensors is presented. In general, doping with transition metals and nonmetals can improve the sensitivity of graphene to gases. This review shows the significance of using theoretical calculations to design novel and efficient gas sensors. The theoretical results obtained so far can be of great help in designing novel and efficient graphene-based gas sensors.","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":"32 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74974655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-30DOI: 10.35745/afm2021v01.01.0004
T. Lin, Sang-Yuan Han, Cheng-Yi Huang, Cheng-Fu Yang, Sufen Wei
In this study, electron beam (E-beam) was used to deposit Ga2O3 films on the sapphire (Al2O3) substratest, then Ga2O3 films were divided three groups, unannealed, annealed at 850 oC, and annealed at 950 oC, respectively. After that, three different methods were investigated to find the optical energy bandgap of un-annealed and annealed Ga2O3 films. First was used n&k analyzer to measure all the optical energy bandgaps of un-annealed and annealed Ga2O3 films directly; Second, all the measured transmittance spectra of un-annealed and annealed Ga2O3 films, then the cut wavelength at the zero transmittance ratio of the extrapolated straight line according the slope of the absorption edge was used to measure optical energy bandgap using the equation of Eg= 12400/cut wavelength. Third, the curve of (αhν)2 against the energy (hν) value was plotted according to Eqs. αhν = C (hν – Eg)1/2 and T = (1 – R)2 exp(-αd), and the extrapolated straight line was used to measure the optical energy bandgap of un-annealed or annealed Ga2O3 films. Finally, the measured results were well compared.
{"title":"Using Different Methods to Measure the Optical Energy Bandgap of Un-annealed and Annealed Ga2O3 Films","authors":"T. Lin, Sang-Yuan Han, Cheng-Yi Huang, Cheng-Fu Yang, Sufen Wei","doi":"10.35745/afm2021v01.01.0004","DOIUrl":"https://doi.org/10.35745/afm2021v01.01.0004","url":null,"abstract":"In this study, electron beam (E-beam) was used to deposit Ga2O3 films on the sapphire (Al2O3) substratest, then Ga2O3 films were divided three groups, unannealed, annealed at 850 oC, and annealed at 950 oC, respectively. After that, three different methods were investigated to find the optical energy bandgap of un-annealed and annealed Ga2O3 films. First was used n&k analyzer to measure all the optical energy bandgaps of un-annealed and annealed Ga2O3 films directly; Second, all the measured transmittance spectra of un-annealed and annealed Ga2O3 films, then the cut wavelength at the zero transmittance ratio of the extrapolated straight line according the slope of the absorption edge was used to measure optical energy bandgap using the equation of Eg= 12400/cut wavelength. Third, the curve of (αhν)2 against the energy (hν) value was plotted according to Eqs. αhν = C (hν – Eg)1/2 and T = (1 – R)2 exp(-αd), and the extrapolated straight line was used to measure the optical energy bandgap of un-annealed or annealed Ga2O3 films. Finally, the measured results were well compared.","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":"73 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84374049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-31DOI: 10.35745/afm2021v01.01.0002
Su-Hua Yang, Wei-Jun Wang
The Sr3La(PO4)3:Eu3+ (SLP:Eu3+) phosphor was prepared with the coprecipitation method, which emited red visible-light along with a near-infrared (NIR) luminescence in the biological window region. The influence of synthesis temperature and Eu3+ doping concentration on the characteristics of the phosphor was discussed. The optimal crystallinity was obtained when the phosphor was doped with 0.7 mol% of Eu3+ and annealed at 1200 °C for 2 h. The particle size was approximately 1 μm. As compared with the SLP:0.01 Eu3+, the photoluminescence intensity of the SLP:0.07 Eu3+ increased by 4.95-fold at wavelength of 615 nm and 3.97- fold at 705 nm. The red SLP:Eu3+ phosphor with a high NIR emission is a potential candidate material for bio-image and bio-sensor applications.
{"title":"Synthesis and Characteristics of Sr3La(PO4)3:Eu3+ Phosphor with Luminescence in NIR Biological Window","authors":"Su-Hua Yang, Wei-Jun Wang","doi":"10.35745/afm2021v01.01.0002","DOIUrl":"https://doi.org/10.35745/afm2021v01.01.0002","url":null,"abstract":"The Sr3La(PO4)3:Eu3+ (SLP:Eu3+) phosphor was prepared with the coprecipitation method, which emited red visible-light along with a near-infrared (NIR) luminescence in the biological window region. The influence of synthesis temperature and Eu3+ doping concentration on the characteristics of the phosphor was discussed. The optimal crystallinity was obtained when the phosphor was doped with 0.7 mol% of Eu3+ and annealed at 1200 °C for 2 h. The particle size was approximately 1 μm. As compared with the SLP:0.01 Eu3+, the photoluminescence intensity of the SLP:0.07 Eu3+ increased by 4.95-fold at wavelength of 615 nm and 3.97- fold at 705 nm. The red SLP:Eu3+ phosphor with a high NIR emission is a potential candidate material for bio-image and bio-sensor applications.","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2021-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78411134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-31DOI: 10.35745/afm2021v01.01.0003
Chun-Chih Hu, Ting-Yu Tai, C. Chan, Yaw-Shyan Fu
We synthesized a novel hybridized perovskite-silica (SiO2) solar cell using an electrospray process under ambient conditions. The Silica scaffold not only provided optical transmission from visible to infrared regions but also blocked the back flow transport of the holes and electrons to reach the electrodes, leading to reduced charge recombination. Moreover, the CH3NH3PbI3 (MAPbI3) film quality can be improved by using the combination of vacuum annealing enhanced crystal growth and the methylamine (CH3NH2, MA) vapor-assisted diffusion at the grain boundaries, due to reduced surface roughness and the re-crystallization of the MAPbI3 film. Photovoltaic performances were evaluated using the glass/ITO/poly (3,4-ethylenedioxythiophene) poly(styrene-sulfonate) (PEDOT:PSS)/SiO2/MAPbI3/C60/BCP/Al device structure, with the champion MAPbI3 based perovskite-silica solar cell exhibited a short-circuit current density of 19.89 mA/cm2, an open-circuit voltage of 0.89 V, a fill factor of 0.50, and a power conversion efficiency of 8.85%.
{"title":"Silica as a Scaffold Layer via Electrospray for MAPbI3 Perovskite-based Solar Cell","authors":"Chun-Chih Hu, Ting-Yu Tai, C. Chan, Yaw-Shyan Fu","doi":"10.35745/afm2021v01.01.0003","DOIUrl":"https://doi.org/10.35745/afm2021v01.01.0003","url":null,"abstract":"We synthesized a novel hybridized perovskite-silica (SiO2) solar cell using an electrospray process under ambient conditions. The Silica scaffold not only provided optical transmission from visible to infrared regions but also blocked the back flow transport of the holes and electrons to reach the electrodes, leading to reduced charge recombination. Moreover, the CH3NH3PbI3 (MAPbI3) film quality can be improved by using the combination of vacuum annealing enhanced crystal growth and the methylamine (CH3NH2, MA) vapor-assisted diffusion at the grain boundaries, due to reduced surface roughness and the re-crystallization of the MAPbI3 film. Photovoltaic performances were evaluated using the glass/ITO/poly (3,4-ethylenedioxythiophene) poly(styrene-sulfonate) (PEDOT:PSS)/SiO2/MAPbI3/C60/BCP/Al device structure, with the champion MAPbI3 based perovskite-silica solar cell exhibited a short-circuit current density of 19.89 mA/cm2, an open-circuit voltage of 0.89 V, a fill factor of 0.50, and a power conversion efficiency of 8.85%.","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":"129 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2021-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80479365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-20DOI: 10.35745/afm2021v01.01.0001
Cheng-Fu Yang, Z. Remeš
The Applied Functional Materials is a peer-reviewed, open-access journal devoted to publishing research papers in the fields of materials engineering and technology. In a modern technological society, engineers and designers must work together with a variety of other professionals in their quest to find materials solutions to complex problems. Fast advances in material science and technology have broadened the horizons of material science whilst simultaneously creating a multitude of challenging problems in every aspect of advanced materials and their applications. Current research is interdisciplinary in nature, reflecting a combination of concepts and methods that often span several areas of fabrication process, synthesis method, numerical simulation, analysis technology, electrical measurement, and other scientific disciplines. This research often investigate materials’ applications for industry or ordinary life of people.
{"title":"Introduction to a New Journal: Applied Functional Materials","authors":"Cheng-Fu Yang, Z. Remeš","doi":"10.35745/afm2021v01.01.0001","DOIUrl":"https://doi.org/10.35745/afm2021v01.01.0001","url":null,"abstract":"The Applied Functional Materials is a peer-reviewed, open-access journal devoted to publishing research papers in the fields of materials engineering and technology. In a modern technological society, engineers and designers must work together with a variety of other professionals in their quest to find materials solutions to complex problems. Fast advances in material science and technology have broadened the horizons of material science whilst simultaneously creating a multitude of challenging problems in every aspect of advanced materials and their applications. Current research is interdisciplinary in nature, reflecting a combination of concepts and methods that often span several areas of fabrication process, synthesis method, numerical simulation, analysis technology, electrical measurement, and other scientific disciplines. This research often investigate materials’ applications for industry or ordinary life of people.","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":"10 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2021-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75325403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1177/22808000211005384
Qing-Qing Wang, Siqing Wang, Tian Zhao, Yan Li, Jie Yang, Yumei Liu, He Zhang, Leiying Miao, Weibin Sun
Objective: Dentin hypersensitivity (DH) is a common oral disease with approximately 41.9% prevalence. Reconstruction of dental hard tissues is the preferred treatment for relieving DH. Here, we applied biomineralization method using oligopeptide simulating cementum protein 1 (CEMP1) to regenerate hard tissues on demineralized dentin.
Methods: The self-assembly and biomineralization property of the oligopeptide were detected by scanning electron microscopy (SEM), circular dichroism spectroscopy, and transmission electron microscopy. Oligopeptide's binding capacity to demineralized dentin was evaluated by SEM and attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR). Remineralization was characterized using SEM, ATR-FTIR, X-ray diffraction, and nanoindentation. Oligopeptide's biocompatibility was evaluated using periodontal ligament cells.
Results: Oligopeptides self-assembled into nano-matrix and templated mineral precursor formation within 24 h. Moreover, oligopeptide nano-matrix bound firmly on demineralized dentin and resisted water rinsing. Then, bound nano-matrix served as a template to initiate nucleation and transformation of hydroxyapatite on demineralized dentin. After 96 h, oligopeptide nano-matrix regenerated an enamel-like tissue layer with a thickness of 15.35 μm, and regenerated crystals occluded dentin tubules with a depth of 31.27 μm. Furthermore, the oligopeptide nano-matrix had good biocompatibility when co-cultured with periodontal ligament cells.
Conclusions: This biomimetic oligopeptide simulating CEMP1 effectively induced remineralization and reconstructed hard tissues on demineralized dentin, providing a potential biomaterial for DH treatment.
{"title":"Biomimetic oligopeptide formed enamel-like tissue and dentin tubule occlusion via mineralization for dentin hypersensitivity treatment.","authors":"Qing-Qing Wang, Siqing Wang, Tian Zhao, Yan Li, Jie Yang, Yumei Liu, He Zhang, Leiying Miao, Weibin Sun","doi":"10.1177/22808000211005384","DOIUrl":"https://doi.org/10.1177/22808000211005384","url":null,"abstract":"<p><strong>Objective: </strong>Dentin hypersensitivity (DH) is a common oral disease with approximately 41.9% prevalence. Reconstruction of dental hard tissues is the preferred treatment for relieving DH. Here, we applied biomineralization method using oligopeptide simulating cementum protein 1 (CEMP1) to regenerate hard tissues on demineralized dentin.</p><p><strong>Methods: </strong>The self-assembly and biomineralization property of the oligopeptide were detected by scanning electron microscopy (SEM), circular dichroism spectroscopy, and transmission electron microscopy. Oligopeptide's binding capacity to demineralized dentin was evaluated by SEM and attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR). Remineralization was characterized using SEM, ATR-FTIR, X-ray diffraction, and nanoindentation. Oligopeptide's biocompatibility was evaluated using periodontal ligament cells.</p><p><strong>Results: </strong>Oligopeptides self-assembled into nano-matrix and templated mineral precursor formation within 24 h. Moreover, oligopeptide nano-matrix bound firmly on demineralized dentin and resisted water rinsing. Then, bound nano-matrix served as a template to initiate nucleation and transformation of hydroxyapatite on demineralized dentin. After 96 h, oligopeptide nano-matrix regenerated an enamel-like tissue layer with a thickness of 15.35 μm, and regenerated crystals occluded dentin tubules with a depth of 31.27 μm. Furthermore, the oligopeptide nano-matrix had good biocompatibility when co-cultured with periodontal ligament cells.</p><p><strong>Conclusions: </strong>This biomimetic oligopeptide simulating CEMP1 effectively induced remineralization and reconstructed hard tissues on demineralized dentin, providing a potential biomaterial for DH treatment.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":"19 ","pages":"22808000211005384"},"PeriodicalIF":2.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/22808000211005384","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25530920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The present study was designed to fabricate a new chitosan-collagen sponge (CCS) for potential wound dressing applications. CCS was fabricated by a 3.0% chitosan mixture with a 1.0% type I collagen (7:3(w/w)) through freeze-drying. Then the dressing was prepared to evaluate its properties through a series of tests. The new-made dressing demonstrated its safety toward NIH3T3 cells. Furthermore, the CCS showed the significant surround inhibition zone than empty controls inoculated by E. coli and S. aureus. Moreover, the moisture rates of CCS were increased more rapidly than the collagen and blank sponge groups. The results revealed that the CCS had the characteristics of nontoxicity, biocompatibility, good antibacterial activity, and water retention. We used a full-thickness excisional wound healing model to evaluate the in vivo efficacy of the new dressing. The results showed remarkable healing at 14th day post-operation compared with injuries treated with collagen only as a negative control in addition to chitosan only. Our results suggest that the chitosan-collagen wound dressing were identified as a new promising candidate for further wound application.
{"title":"Effects of chitosan-collagen dressing on wound healing in vitro and in vivo assays.","authors":"Min-Xia Zhang, Wan-Yi Zhao, Qing-Qing Fang, Xiao-Feng Wang, Chun-Ye Chen, Bang-Hui Shi, Bin Zheng, Shou-Jie Wang, Wei-Qiang Tan, Li-Hong Wu","doi":"10.1177/2280800021989698","DOIUrl":"https://doi.org/10.1177/2280800021989698","url":null,"abstract":"<p><p>The present study was designed to fabricate a new chitosan-collagen sponge (CCS) for potential wound dressing applications. CCS was fabricated by a 3.0% chitosan mixture with a 1.0% type I collagen (7:3(w/w)) through freeze-drying. Then the dressing was prepared to evaluate its properties through a series of tests. The new-made dressing demonstrated its safety toward NIH3T3 cells. Furthermore, the CCS showed the significant surround inhibition zone than empty controls inoculated by <i>E. coli</i> and <i>S. aureus</i>. Moreover, the moisture rates of CCS were increased more rapidly than the collagen and blank sponge groups. The results revealed that the CCS had the characteristics of nontoxicity, biocompatibility, good antibacterial activity, and water retention. We used a full-thickness excisional wound healing model to evaluate the in vivo efficacy of the new dressing. The results showed remarkable healing at 14th day post-operation compared with injuries treated with collagen only as a negative control in addition to chitosan only. Our results suggest that the chitosan-collagen wound dressing were identified as a new promising candidate for further wound application.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":"19 ","pages":"2280800021989698"},"PeriodicalIF":2.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2280800021989698","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25348412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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