Journal of Ayurveda and Integrative Medicine最新文献

{"title":"Efficacy of Mamsyadi Ghana capsule and Saraswatarista in the management of Insomnia Disorder - A Randomized Controlled Clinical Trial","authors":"M. Manasa ,&nbsp;Aswini Padmashali ,&nbsp;Basavaraj R. Tubaki ,&nbsp;Manisha","doi":"10.1016/j.jaim.2025.101160","DOIUrl":"10.1016/j.jaim.2025.101160","url":null,"abstract":"<div><h3>Background</h3><div>One of the prevalent sleep disorders is insomnia disorder. Current pharmacotherapy have limitations like dependence, tolerance and withdrawal effects. Ayurveda drugs remains to be explored.</div></div><div><h3>Objectives</h3><div>Can Ayurveda intervention (<em>Mamsyadi Ghana</em> Capsule and <em>Saraswatharista</em>) play a role in Insomnia disorder.</div></div><div><h3>Material and Methods</h3><div>50 patients meeting the diagnostic criteria of Insomnia Disorder (DSM 5), age group 20–70 years, either sex participated in the study. They were randomly divided and Ayurveda group received <em>Mamsyadi Ghana</em> Capsule 500 mg, <em>Saraswatharista</em> 10 ml, with equal quantity of water after food, both thrice a day for 30 days. Zolpidem group received tablet Zolpidem 10 mg once a day at bed time. Evaluations were done through Insomnia severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness scale (ESS), Sleep diary parameters, Depression Anxiety and Stress Scale (DASS), Quality of Life – SF 36 Questionnaire and UKU side effect rating scale. Clinical assessments were at baseline, 15th and 30th day.</div></div><div><h3>Results</h3><div>The study showed that Ayurveda intervention produced significant improvement and was comparable to Zolpidem. Both interventions were comparable in ISI, PSQI, ESS, DASS scale, sleep diary parameters and most of the components of SF-36. Role of limitations due to emotional problems component showed better improvement in Ayurveda group (p = 0.01). Within group analysis showed improvement in both the groups. Five patients had adverse effects with Zolpidem and nil with ayurveda group.</div></div><div><h3>Conclusions</h3><div>The study showed that effect of Ayurveda interventions (<em>Mamsyadi Ghana</em> Capsule and <em>Saraswatharista</em>) is comparable to zolpidem in Insomnia Disorder. Ayurveda intervention had better improvement on quality of life and had good safety profile.</div></div><div><h3>Ctri registration number</h3><div>CTRI/2021/12/038809.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 4","pages":"Article 101160"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144572111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ayush at crossroads - A challenge of opportunities","authors":"Girish Tillu","doi":"10.1016/j.jaim.2025.101254","DOIUrl":"10.1016/j.jaim.2025.101254","url":null,"abstract":"","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 4","pages":"Article 101254"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144828741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroprotective potential of dombeya wallichii ameliorates Parkinson's activity in paraquat-induced Rat's model via modulation of neuro-inflammatory cytokines","authors":"Hafsa Tariq ,&nbsp;Khizra Ishfaq ,&nbsp;Talha Chauhdari ,&nbsp;Fatima Sarwar ,&nbsp;Fazeela Ismail","doi":"10.1016/j.jaim.2025.101162","DOIUrl":"10.1016/j.jaim.2025.101162","url":null,"abstract":"<div><h3>Background</h3><div>Parkinson's disease (PD) is a prevalent age-related neurodegenerative condition that develops gradually and is observed in around 1 % of the elderly population. Lately, there has been an increasing curiosity about the possibilities of phyto-components for the treatment of PD due to their rich array of active compounds, notably antioxidants and anti-inflammatory agents.</div></div><div><h3>Objective</h3><div>Our objective was to assess the impact of an ethanolic extract from <em>Dombeya wallichii</em>, which has antioxidant properties, on the Parkinsonian rat's model.</div></div><div><h3>Material and methods</h3><div>Rats received 10 mg/kg paraquat to assess its antiparkinsonian effects. They were treated with ethanolic extract of <em>Dombeya wallichii</em> (200, 400, 600 mg/kg) for 21 days, 1 h after paraquat. Behavioral aspects were evaluated before sacrifice. On day 22, rats were euthanized, and their bodies examined for changes in antioxidant enzymes (superoxide dismutase, glutathione, malondialdehyde, catalase), neurotransmitter levels (dopamine, noradrenaline, serotonin, acetylcholinesterase), mRNA expression and neuroinflammatory cytokines (Interleukin-1β, Tumor Necrosis Factor-α, nuclear factor kappa B, Interleukin-6).</div></div><div><h3>Results</h3><div>The ethanolic extract of <em>Dombeya wallichii</em> reduced paraquat-induced motor deficits in the rotarod, hole board, akinesia, and forelimb hanging tests. It also improved biochemical and neuroinflammatory markers by lowering oxidative stress and inflammatory cytokines, showing antioxidant and anti-inflammatory activities. q-RT-PCR revealed that <em>D. wallichii</em> downregulated α-synuclein, Interleukin-1β, nuclear factor kappa B, and Tumor Necrosis Factor-α, while mRNA expression indicated neuroprotection.</div></div><div><h3>Conclusion</h3><div>These findings suggest that <em>Dombeya wallichii</em> could be a viable candidate for Parkinson's disease treatment, owing to its antioxidant and anti-inflammatory properties.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 4","pages":"Article 101162"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-silico docking analysis of bioactive compounds sourced from Punica granatum peel extract: Approaching a precision solution for ovarian cancer","authors":"Swarupa Hatolkar ,&nbsp;Aishwarya Patil ,&nbsp;Hiramoni Lahkar ,&nbsp;Poulomi Chakraborty ,&nbsp;Bhagyashree Vinit Gokhale ,&nbsp;Aarti Shastri","doi":"10.1016/j.jaim.2025.101125","DOIUrl":"10.1016/j.jaim.2025.101125","url":null,"abstract":"<div><h3>Background</h3><div>The MAPK signalling pathways, particularly those involving EGFR and VEGFR, play a pivotal role in the initiation and progression of ovarian cancer. Inadequate regulation of these pathways may lead to uncontrolled cell proliferation, angiogenesis, and metastasis. Targeting mitogen-activated protein kinases (MAPKs), including the epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR), has demonstrated significant potential in restraining cancer cell proliferation and angiogenesis, representing a promising avenue among various therapeutic strategies.</div></div><div><h3>Objectives</h3><div>This manuscript aims to investigate the possibility of Mashi a pomegranate peel extract for ovarian cancer treatment, specifically targeting MAPKs (EGFR and VEGFR). Pomegranate (Punica granatum) is a well-known fruit whose varied portions have been used in traditional medicine for ages.</div></div><div><h3>Materials and methods</h3><div>In silico docking of bioactive compounds extracted from the pomegranate peel extract was done using the Autodock 4.2.6 software. A total of 10 two-dimensional ligands were generated with Pubchem site. The targeted proteins VEGFR, EGFR, MAPK, and MAPK8 were docked with the ligands (Sphondin, Isorhamnetin, Lupinine, Ellagic acid, and Citric acid) which were bioactive ingredients identified from pomegranate peel extract.</div></div><div><h3>Results</h3><div>It was observed that the binding energy of protein MAPK 8, MAPK 14, and VGFR was higher to the ligand at ellagic acid at -8.25kcal/mol, -7.61kcal/mol, and - 5.85kcal/mol respectively. However, EGFR observed to bind with ligand Isorhamnetin at -7.48kcal/mol.</div></div><div><h3>Conclusion</h3><div>The MAPK signalling pathways, specifically involving EGFR and VEGFR, play a crucial role in the initiation and dissemination of ovarian cancer. Dysregulation of these pathways can lead to unrestrained cell proliferation, angiogenesis, and metastasis. Our study revealed favorable binding energy between targeted proteins and ligands. Consequently, we infer that proteins exhibiting robust binding energy with bioactive compounds from pomegranate peel extract may exert regulatory control over the signalling pathways. This implies that EGFR and VEGFR can modulate signals by binding to the bioactive compounds in pomegranate peel extract, thereby regulating the MAPK pathway and ultimately curtailing uncontrolled cell proliferation, angiogenesis, and tumor metastasis. supported by simulation studies results.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 4","pages":"Article 101125"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ameliorative effect of Inula racemosa Hook. F root extract against diethylnitrosamine induced hepatic damage in murine model","authors":"Smriti Jamwal ,&nbsp;Rakesh Kumar ,&nbsp;R.K. Asrani ,&nbsp;Ankita ,&nbsp;Abhishek Verma ,&nbsp;Ekta Bisht ,&nbsp;Shreya Katoch ,&nbsp;Vikram Patial ,&nbsp;Vinesh Sharma ,&nbsp;Adarsh Kumar ,&nbsp;R.D. Patil","doi":"10.1016/j.jaim.2025.101173","DOIUrl":"10.1016/j.jaim.2025.101173","url":null,"abstract":"<div><h3>Background</h3><div>Liver disease is one of the most serious health problems worldwide. In the present scenario, the available therapies for liver ailments are not very effective and systemic toxicity inhibits their long-term use. Several medicinal plants have demonstrated promising effects against liver damage. These plants can help to prevent liver injury, reduce inflammation, enhance liver detoxification, and support liver cell regeneration and one such medicinal plant is <em>Inula racemosa.</em> The bioactive constituents present in the root extract of <em>Inula racemosa</em> i.e. alantolactone and isoalantolactone are responsible for its hepatoprotective potential.</div></div><div><h3>Objectives</h3><div>The current study aimed to elucidate the preventive action of <em>Inula racemosa</em> root extract against chemically-induced liver damage using Diethylnitrosamine (DEN).</div></div><div><h3>Material and methods</h3><div>Sprague Dawley (SD) 42-male rats were used in a 10-week study to examine the hepatoprotective effects of 3 different dosages (100, 250, and 500 mg/kg body weight) of <em>Inula racemosa</em> root extract against DEN-induced liver damage. The investigation included gross pathology, histopathology, immunohistochemistry (TGF-β and NF- κB), ultrasonography, and serum biochemistry (ALT, AST, ALP, Total protein, Albumin, Creatinine, and BUN).</div></div><div><h3>Results</h3><div>The <em>in vivo</em> research establishes <em>Inula racemosa</em> root extract's hepatoprotective efficacy by ameliorating biochemical parameters, lipid peroxidation, gross and histopathological alterations, and reduced immunohistochemical expression of TGF-β and NF- κB. The greatest defense against chemically-induced liver damage was provided by the highest dosage of the extract i.e. 500 mg/kg body weight.</div></div><div><h3>Conclusions</h3><div>The results of this investigation showed that the <em>Inula racemosa</em> root extract showed hepatoprotective activity against DEN-induced liver damage in the rat model.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 4","pages":"Article 101173"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144579650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-invasive management of Thandaga vaatham (lumbar spondylosis) through Siddha Varmam therapy - A case report","authors":"Shunmugaram Shenbagaraj,&nbsp;Saraswathi Balasubramanian,&nbsp;Deepa Ravichandran,&nbsp;Vinodini Ramamoorthy,&nbsp;Sathiyarajeswaran Parameswaran,&nbsp;Shyamala Rajkumar","doi":"10.1016/j.jaim.2025.101171","DOIUrl":"10.1016/j.jaim.2025.101171","url":null,"abstract":"<div><div>A 32-year-old female homemaker came with a complaints of chronic low back pain, radiating to both lower limbs, stiffness especially in the morning difficulty in walking and standing with intensified pain during household chores for two years. She was diagnosed with <em>Tantaka vātam,</em> one of the eighty types of vātam disease which is equivalent to lumbar spondylosis. She was treated with therapeutic <em>Varmam</em> manipulations in every 7 days for a period of 48 days and followed for six months. Oswestry Disability Index, Siddha based diagnostic parameters were used to assess the clinical efficacy and no adverse events were noted during the treatment course and follow up period. This case report has provided a promising non-invasive and cost-effective therapeutic indication for the management of <em>Tantaka vātam</em> (lumbar spondylosis).</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 4","pages":"Article 101171"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144579651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ayurveda management of severe coronary artery calcification in a triple vessel disease patient - a case report","authors":"Divya Kajaria,&nbsp;Punam N. Khobarkar","doi":"10.1016/j.jaim.2025.101165","DOIUrl":"10.1016/j.jaim.2025.101165","url":null,"abstract":"<div><div>The coronary artery calcium score is a tool for predicting the risk of coronary artery disease (CAD). Severe coronary artery calcification, particularly in the context of triple vessel disease, poses a considerable therapeutic difficulty for standard medical procedures. The treatment modality for heavily calcified coronary arteries is coronary stenting or coronary artery bypass grafting. Severe calcification reduces the efficacy of stent deployment during PCI. Severe coronary calcification complicates the surgical revascularization process, often leading to increased procedural risks and reduced long-term success rates. A 65-year-old female patient having severe coronary artery calcification (triple vessel disease) is treated with holistic Ayurveda management. It is observed that there is a 17.78 % decrease in the calcium score after purgation therapy and an additional 25.01 % decrease in the calcium score after <em>Rasayana</em> therapy.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 4","pages":"Article 101165"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zebrafish models for studying central nervous system effects of Ayurvedic medicinal plants","authors":"Pallab Chakraborty ,&nbsp;Subharthi Pal ,&nbsp;David S. Galstyan ,&nbsp;Elena V. Petersen ,&nbsp;Tamara G. Amstislavskaya ,&nbsp;Tatiana O. Kolesnikova ,&nbsp;Murilo S. de Abreu ,&nbsp;Allan V. Kalueff","doi":"10.1016/j.jaim.2025.101169","DOIUrl":"10.1016/j.jaim.2025.101169","url":null,"abstract":"<div><div>Traditional Indian medicine (<em>Ayurveda)</em> has a long history of treating central nervous system (CNS) disorders. <em>Ayurvedic</em> plants are typically rich in flavonoids, lignans, sterols, tannins and alkaloids that exert potent anti-inflammatory, anti-oxidant, neuroprotective and neurotropic effects in both humans and rodents. The zebrafish (<em>Danio rerio</em>) has emerged as a useful model species and a powerful vertebrate in vivo system for CNS disease modeling and drug screening. As zebrafish continue to demonstrate their growing utility for studying a wide range of pharmaceutical therapies, including Chinese and American traditional medicines, here we discuss CNS effects of various <em>Ayurvedic</em> medicinal plants, and how they can be further elucidated using zebrafish models. We also evaluate the existing challenges and limitations of using zebrafish models for studying <em>Ayurvedic</em> pharmacotherapy, as well as outline future directions of translational research in this field.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 4","pages":"Article 101169"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144570641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Apamarga Kshara Taila on diabetic pressure ulcer – A case report","authors":"Gopika G,&nbsp;Rajeshwari P.N","doi":"10.1016/j.jaim.2025.101167","DOIUrl":"10.1016/j.jaim.2025.101167","url":null,"abstract":"<div><div>Diabetes mellitus is a group of metabolic disorders with chronic hyperglycemia, and Diabetic Pressure Ulcer (DPU) is one of the major complications. DPU develops due to the effect of continuous forces on the distal pulp, causing progressive skin ischemia occurring above bony prominence. 62 million people are affected with diabetes in India, and among that 25 % develop DPU. Neuropathic and ischemic components account for 45 %–60 % of ulcers, which, if untreated, can lead to the risk of amputation. According to Ayurveda, characteristic features of DPU can be correlated with the features of <em>Dushta vrana</em> and treatment can be planned based on <em>Dushta vrana</em> and <em>Madhumehaja vranas</em>. Acharya Susruta highlighted the importance of <em>kshara</em> for wound debridement in treatment of non-healing ulcers. A 63-year-old male with known case of diabetes mellitus for 15 years presented with a wound over the big toe of his right foot. The wound is 9-month-old. It was associated with loss of sensation, swelling, and discoloration. Treatment was given with the external application of <em>Apamarga kshara taila</em> with internal medications for 2 months. The size of the ulcer measuring 1.5cm in length, 1cm in breadth, and 4 cm in depth completely healed by 2 months of treatment. The utilization of <em>Apamarga kshara taila,</em> along with internal medications, has demonstrated significant efficacy in the management of DPU.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 4","pages":"Article 101167"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144596776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Naturopathy and yoga-based interventions modify risk factors of peripheral neuropathy and improve nerve conduction among Type-2 Diabetes Mellitus patients","authors":"Koushik Gupta Somisetty ,&nbsp;Geetha B. Shetty ,&nbsp;K.J. Sujatha ,&nbsp;Prashanth Shetty","doi":"10.1016/j.jaim.2025.101147","DOIUrl":"10.1016/j.jaim.2025.101147","url":null,"abstract":"<div><h3>Background</h3><div>With the high prevalence of diabetic peripheral neuropathy among Type -2 Diabetes Mellitus (T2DM) patients, diagnosis and management of subclinical peripheral neuropathy are gaining concern to prevent its complications. A wide variety of alternative lifestyle interventions emphasizing improving glycemic control, promoting weight loss, and a prudent diet were found to be effective in improving nerve conduction abnormalities individually.</div></div><div><h3>Objective</h3><div>To study the impact of naturopathy and yoga intervention in the prevention and management of nerve damage among T2DM-associated neuropathic signs.</div></div><div><h3>Methods</h3><div>In this matched control trial (gender and age-matched), 76 patients with subclinical diabetic peripheral neuropathy were recruited to (i) Intervention Group (IG), n=38 who received naturopathy and yoga-based interventions for 9 days, (ii) Control Group (CG), n=38 continued regular oral hypoglycemic medications. Neuroelectrophysiological parameters like amplitude and velocity of bilateral median motor and sensory and deep peroneal nerve, fasting blood glucose, postprandial blood glucose Homeostatic Model for Insulin Resistance (HOMA-IR), steady state beta cell function (%B), and insulin sensitivity (%S) were assessed at baseline and after 9 days.</div></div><div><h3>Results</h3><div>Weight, BMI, FBG, HOMA-IR, and %S significantly (p&lt;0.05) improved among IG. In comparison, FBG, PPBG, %S, right median sensory amplitude, and left median sensory nerve conduction velocity had shown a significant difference between the groups.</div></div><div><h3>Conclusion</h3><div>A significant reduction in modifiable risk factors of neuropathy like insulin resistance and weight after the intervention shows the effectiveness of lifestyle-based naturopathy and yoga intervention in preventing peripheral neuropathy among diabetics.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 4","pages":"Article 101147"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}