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Five years of disease-free survival in a case of recurrent, post-op, grade 3, stage 2, Malignant Spindle Cell Melanoma treated with Ayurvedic medicines: A case report 一例术后复发、3 级、2 期恶性纺锤形细胞黑色素瘤患者接受阿育吠陀药物治疗后获得五年无病生存:病例报告
IF 1.7 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 DOI: 10.1016/j.jaim.2024.100976
Ranjit G. Nimbalkar , Anil T. Pawar , Amol A. Tagalpallewar , Akshay M. Baheti , Satish Chapadgaonkar , Manasi R. Nimbalkar

Malignant spindle cell melanoma is a rare cancer with a questionable prognosis because of limited published case reports. This article discusses a male patient with a history of Spindle cell melanoma tumor, Rt heel, Grade 3 (Gr 3) Stage 2 (St 2) seen in our OPD treated with supporting herbo-mineral combination of Ayurvedic medicine. Such types of cancers are of concern and can be more troublesome to the patient. The initial chief complaint of the patient was a palpable corn-like growth in the right heel, which was surgically removed at that time. When it recurred after one year, it was investigated thoroughly and it was found malignant, and then operated again.

The patient came to us after his second operation. After appropriate analysis based on Ayurvedic and modern parameters, the patient was treated with Ayurved treatment. As there was no other treatment suggested by oncologists, he was on supportive Ayurvedic treatment only. Ayurvedic treatment continued for 2 years afterwards. The treatment module showed complete relief in the symptoms (100%), by the end of treatment. Follow-up PET scans showed further improvement and a complete reversal of residual disease was observed. The last PET scan did not show any evidence of abnormality. To date, there has been no recurrence and the patient has been living completely normally for the last almost 5 years (karnofsky score 90/100). It can be concluded that the addition of Ayurvedic treatment might have helped this patient of malignant spindle cell melanoma for regression of residual disease, prevention of metastasis to date, and a good quality of life. We have observed 5+ years of disease-free survival and near-normal quality of life for this patient, and still ongoing.

恶性纺锤形细胞黑色素瘤是一种罕见的癌症,由于已发表的病例报告有限,其预后值得怀疑。本文讨论的是一名男性患者的病史,他患有右足跟部纺锤形细胞黑色素瘤,3级(Gr 3)2期(St 2),在本院手术室接受了阿育吠陀草药-矿物质联合疗法的治疗。这类癌症令人担忧,也会给患者带来更多麻烦。患者最初的主诉是右脚后跟可触及的粟粒样增生,当时已通过手术将其切除。一年后复发,经过彻底检查,发现是恶性肿瘤,于是再次进行了手术。根据阿育吠陀疗法和现代参数进行适当分析后,患者接受了阿育吠陀疗法。由于肿瘤专家没有提出其他治疗建议,他只接受了辅助性的阿育吠陀治疗。此后,阿育吠陀疗法持续了两年。治疗模块显示,治疗结束时症状完全缓解(100%)。后续的正电子发射计算机断层扫描显示病情进一步好转,残留疾病完全逆转。最后一次 PET 扫描未显示任何异常证据。迄今为止,患者的病情没有复发,在过去近 5 年的时间里生活完全正常(卡诺夫斯基评分 90/100)。由此可以得出结论,采用阿育吠陀疗法可能有助于这位恶性纺锤形细胞黑色素瘤患者消退残留病灶,防止转移,并获得良好的生活质量。据我们观察,这名患者的无病生存期已超过 5 年,生活质量接近正常,而且仍在继续。
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引用次数: 0
Letter to editor - Assessing the efficacy of meditation in the management of infertility 致编辑的信 - 评估冥想在不孕症治疗中的疗效。
IF 1.7 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 DOI: 10.1016/j.jaim.2024.100965
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引用次数: 0
The art and science of research methodology, biostatistics, manuscript writing, and publication ethics: An invigorating training for improving research aptitudes in southern Indian biomedical institutions 研究方法、生物统计学、手稿写作和出版伦理的艺术与科学:为提高印度南部生物医学机构的研究能力而开展的振奋人心的培训。
IF 1.7 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 DOI: 10.1016/j.jaim.2024.100996
Pitchai Balakumar, Shubhada Nagarkar, Gangaboriah Bilagumba, Ramesh Alluri, Gowraganahalli Jagadeesh

The basic concepts of research are learned through systematic literature searches which form the basis of a research statement and research topic. Then the research question, hypothesis, aim, and objectives, as well as the experimental design, are developed. Given the context provided, the primary focus is on the importance of adequately training postgraduates and young research investigators in research methodology and project development. It is evident that there is a lack of proper training in these areas, and the rapid expansion of colleges in India exacerbates this issue. To address this, research students must receive comprehensive instruction in scientific research methodology, experimental design, statistics, scientific writing, publishing, and research ethics. Our team has been conducting workshops and symposia for more than two decades to improve the current teaching methods in these areas. Most recently, we organized a series of national and international workshops and seminars in multiple states across India to fortify the core concepts of scientific research for students and faculty members. This report highlights the key aspects of these workshops and the positive outcomes experienced by participants.

通过系统的文献检索学习研究的基本概念,这构成了研究说明和研究课题的基础。然后提出研究问题、假设、目的和目标以及实验设计。鉴于所提供的背景,主要重点在于充分培训研究生和年轻研究调查人员掌握研究方法和项目开发的重要性。显然,这些领域缺乏适当的培训,而印度高校的迅速扩张又加剧了这一问题。为了解决这个问题,研究生必须接受科学研究方法、实验设计、统计、科学写作、出版和研究伦理方面的全面指导。二十多年来,我们的团队一直在举办研讨会和专题讨论会,以改进这些领域的现行教学方法。最近,我们在印度多个邦举办了一系列国内和国际讲习班和研讨会,以强化学生和教师的科学研究核心概念。本报告重点介绍了这些讲习班的主要内容以及参与者所取得的积极成果。
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引用次数: 0
Ayurveda Management of IUGR due to single umbilical artery: A case report 阿育吠陀治疗单脐动脉导致的 IUGR:病例报告。
IF 1.7 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 DOI: 10.1016/j.jaim.2024.100974
Asha Sreedhar , Aswini Mohan L , S. Parvathy

IUGR is defined as a rate of fetal growth that is less than normal for the expected growth potential of a specific infant. Fetuses with isolated single umbilical artery are at higher risk of prematurity, IUGR(Intra uterine growth restriction), and intrauterine death. Ayurveda provides a holistic approach towards garbhini paricharya (antenatal care). Nabhinadi (umbilical cord) nourishes the fetus, and abnormalities result in garbhashosha. This is a case report of IUGR associated with a single umbilical artery with no other abnormalities. The obstetric scan revealed decreased abdominal circumference and falling growth parameters. Ayurvedic medicines with brimhana, balya, prajasthapana actions were given. The outcome was a full-term baby of birth weight 2.5kg through vaginal delivery.

IUGR 的定义是胎儿的生长速度低于特定婴儿的预期生长潜力的正常值。有孤立单脐动脉的胎儿发生早产、IUGR(子宫内生长受限)和宫内死亡的风险较高。阿育吠陀为 garbhini paricharya(产前护理)提供了一种整体方法。Nabhinadi(脐带)为胎儿提供营养,脐带异常会导致胎儿畸形。这是一例与单脐动脉相关的 IUGR 病例,无其他异常。产科扫描显示腹围减小,生长指标下降。医生给予了具有 brimhana、balya 和 prajasthapana 作用的阿育吠陀药物。结果经阴道分娩产下一名足月婴儿,出生体重 2.5 千克。
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引用次数: 0
Antidiabetic and antioxidant properties of Boswellia sacra oleo-gum in streptozotocin-induced diabetic rats 乳香油胶在链脲佐菌素诱导的糖尿病大鼠中的抗糖尿病和抗氧化特性
IF 1.7 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 DOI: 10.1016/j.jaim.2024.101014
Hisham Al-Matubsi , Luay Rashan , Walid Aburayyan , Othman Al Hanbali , Duaa Abuarqoub , Thomas Efferth
<div><h3>Background</h3><p>Diabetes is a metabolic disorder requiring the administration of insulin or other oral hypoglycemic medicines. Although metformin is a popular prescription for type 2 diabetes, long-term use of chemotherapy-based diabetes medications can be hazardous. As a result, novel plant medicines with a high concentration of bioactive molecules, no harmful side effects, and potent pharmacological effects must be found. Edible Boswellia sacra (<em>B. sacra</em>) Flueck oleo-gum resin is widely utilized to treat many clinical diseases in traditional Arab, Chinese, African, and Ayurvedic medicine.</p></div><div><h3>Objective</h3><p>The goal of this study was to examine the possible therapeutic benefits of several <em>B. sacra</em> oleo-gum resin extracts on rat streptozotocin (STZ)-induced hyperglycemia (Type II).</p></div><div><h3>Materials and methods</h3><p>For 29 days, hyperglycemic rats are given either metformin (the reference drug; 250 mg/kg body weight per day) or several <em>B. sacra</em> extracts (ethanol, methanol, hydrodistilled, ethyl acetate, and acetone extracts) at doses of 200 or 400 mg/kg/day. Blood glucose levels and body weights were measured before the initiation and at 7, 11, 16, 22, and 29 days after oral treatment. Furthermore, an oral glucose tolerance test (OGTT) was carried out. At the end of the study, the rats were euthanized, and blood samples were obtained to evaluate cytokines (interleukin (IL-)2 and IL-8), reduced glutathione (GSH), superoxide dismutase (SOD), and serum insulin levels. The pancreas and liver tissues were rapidly excised, washed, fixed, and kept in a 10% formalin buffer for histological examination.</p></div><div><h3>Results</h3><p><em>B.</em> sacra's ethanolic extract had the greatest concentration of total pentacyclic triterpenic acid (PTA) (391.52 mg/g) in comparison to the other extracts. The lower dose of <em>B. sacra</em> ethanol extract, 200 mg/kg/day, reduces blood glucose levels more efficiently than the higher dose of 400 mg/kg/day. In a 180-min OGTT, diabetic rats given ethanol extract (200 mg/kg) performed no better than control rats and even outperformed those given the reference medication metformin. Additionally, ethanol extract (200 mg/kg)- or metformin-treated diabetic rats gained weight. This was associated with a significant (<em>p</em> < 0.05) decrease in serum levels of IL-2 and IL-8, a reduction in oxidative stress as evidenced by a significant (<em>p</em> < 0.05) increase in SOD and GSH compared to the untreated diabetic group, and a significant (<em>p</em> < 0.05) increase in serum insulin levels compared to normal plasma rat levels. These discoveries, which were eventually confirmed by histochemical assays, indicated that the ethanol extract of <em>B. sacra</em> greatly enhanced the cellular architecture of pancreatic and liver cells.</p></div><div><h3>Conclusion</h3><p>The present investigation indicates that the ethanol extract of <em>B. sacra</em> o
背景糖尿病是一种代谢紊乱疾病,需要使用胰岛素或其他口服降糖药物。虽然二甲双胍是治疗 2 型糖尿病的常用处方药,但长期使用化疗类糖尿病药物可能会对人体造成危害。因此,必须找到生物活性分子浓度高、无毒副作用、药理作用强的新型植物药。在传统的阿拉伯、中国、非洲和阿育吠陀医学中,食用乳香(Boswellia sacra (B. sacra) Flueck)油胶树脂被广泛用于治疗许多临床疾病。本研究的目的是探讨几种乳香油胶树脂提取物对大鼠链脲佐菌素(STZ)诱导的高血糖症(II 型)可能具有的治疗效果。材料和方法 给高血糖大鼠服用二甲双胍(参考药物;每天 250 毫克/千克体重)或几种 B. sacra 提取物(乙醇、甲醇、氢化蒸馏、乙酸乙酯和丙酮提取物),剂量为 200 或 400 毫克/千克/天,为期 29 天。在开始治疗前以及口服治疗后的 7、11、16、22 和 29 天测量血糖水平和体重。此外,还进行了口服葡萄糖耐量试验(OGTT)。研究结束时,对大鼠实施安乐死,并采集血液样本以评估细胞因子(白细胞介素(IL-)2 和 IL-8)、还原型谷胱甘肽(GSH)、超氧化物歧化酶(SOD)和血清胰岛素水平。胰腺和肝脏组织被迅速切除、清洗、固定,并保存在 10% 福尔马林缓冲液中进行组织学检查。低剂量的 B. sacra 乙醇提取物(200 毫克/千克/天)比高剂量(400 毫克/千克/天)更有效地降低血糖水平。在 180 分钟的 OGTT 试验中,服用乙醇提取物(200 毫克/千克)的糖尿病大鼠的表现并不比对照组大鼠好,甚至还优于服用二甲双胍的大鼠。此外,服用乙醇提取物(200 毫克/千克)或二甲双胍的糖尿病大鼠体重增加。这与血清中 IL-2 和 IL-8 水平的显著下降(p <0.05)、氧化应激的减少(与未治疗的糖尿病组相比,SOD 和 GSH 的显著增加(p <0.05)以及血清中胰岛素水平与正常血浆大鼠水平相比的显著增加(p <0.05)有关。这些发现最终通过组织化学分析得到了证实,表明 B. sacra 的乙醇提取物大大增强了胰腺和肝细胞的细胞结构。本研究表明,囊果油树脂乙醇提取物中含有大量乙酰基-β-乳香酸(β-ABA)和乙酰基-11-酮基-β-乳香酸(AKBA)。此外,它还能恢复 STZ 诱导的糖尿病大鼠的肝细胞,保护胰腺免受氧化损伤。因此,目前的研究结果为将 B. sacra 用于糖尿病及相关并发症的医疗管理提供了科学依据。要确定乙醇提取物的确切作用机制,必须对这些提取物的代谢特征进行更多的研究。
{"title":"Antidiabetic and antioxidant properties of Boswellia sacra oleo-gum in streptozotocin-induced diabetic rats","authors":"Hisham Al-Matubsi ,&nbsp;Luay Rashan ,&nbsp;Walid Aburayyan ,&nbsp;Othman Al Hanbali ,&nbsp;Duaa Abuarqoub ,&nbsp;Thomas Efferth","doi":"10.1016/j.jaim.2024.101014","DOIUrl":"10.1016/j.jaim.2024.101014","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;p&gt;Diabetes is a metabolic disorder requiring the administration of insulin or other oral hypoglycemic medicines. Although metformin is a popular prescription for type 2 diabetes, long-term use of chemotherapy-based diabetes medications can be hazardous. As a result, novel plant medicines with a high concentration of bioactive molecules, no harmful side effects, and potent pharmacological effects must be found. Edible Boswellia sacra (&lt;em&gt;B. sacra&lt;/em&gt;) Flueck oleo-gum resin is widely utilized to treat many clinical diseases in traditional Arab, Chinese, African, and Ayurvedic medicine.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;p&gt;The goal of this study was to examine the possible therapeutic benefits of several &lt;em&gt;B. sacra&lt;/em&gt; oleo-gum resin extracts on rat streptozotocin (STZ)-induced hyperglycemia (Type II).&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Materials and methods&lt;/h3&gt;&lt;p&gt;For 29 days, hyperglycemic rats are given either metformin (the reference drug; 250 mg/kg body weight per day) or several &lt;em&gt;B. sacra&lt;/em&gt; extracts (ethanol, methanol, hydrodistilled, ethyl acetate, and acetone extracts) at doses of 200 or 400 mg/kg/day. Blood glucose levels and body weights were measured before the initiation and at 7, 11, 16, 22, and 29 days after oral treatment. Furthermore, an oral glucose tolerance test (OGTT) was carried out. At the end of the study, the rats were euthanized, and blood samples were obtained to evaluate cytokines (interleukin (IL-)2 and IL-8), reduced glutathione (GSH), superoxide dismutase (SOD), and serum insulin levels. The pancreas and liver tissues were rapidly excised, washed, fixed, and kept in a 10% formalin buffer for histological examination.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;&lt;em&gt;B.&lt;/em&gt; sacra's ethanolic extract had the greatest concentration of total pentacyclic triterpenic acid (PTA) (391.52 mg/g) in comparison to the other extracts. The lower dose of &lt;em&gt;B. sacra&lt;/em&gt; ethanol extract, 200 mg/kg/day, reduces blood glucose levels more efficiently than the higher dose of 400 mg/kg/day. In a 180-min OGTT, diabetic rats given ethanol extract (200 mg/kg) performed no better than control rats and even outperformed those given the reference medication metformin. Additionally, ethanol extract (200 mg/kg)- or metformin-treated diabetic rats gained weight. This was associated with a significant (&lt;em&gt;p&lt;/em&gt; &lt; 0.05) decrease in serum levels of IL-2 and IL-8, a reduction in oxidative stress as evidenced by a significant (&lt;em&gt;p&lt;/em&gt; &lt; 0.05) increase in SOD and GSH compared to the untreated diabetic group, and a significant (&lt;em&gt;p&lt;/em&gt; &lt; 0.05) increase in serum insulin levels compared to normal plasma rat levels. These discoveries, which were eventually confirmed by histochemical assays, indicated that the ethanol extract of &lt;em&gt;B. sacra&lt;/em&gt; greatly enhanced the cellular architecture of pancreatic and liver cells.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;p&gt;The present investigation indicates that the ethanol extract of &lt;em&gt;B. sacra&lt;/em&gt; o","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"15 4","pages":"Article 101014"},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624001293/pdfft?md5=4f32a076991ec11158a55d3df0efb7ca&pid=1-s2.0-S0975947624001293-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142011715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Green gram soup and barley porridge as dietary interventions for management of premenstrual syndrome in adolescent girl: A case report 将青稞汤和大麦粥作为治疗少女经前综合征的饮食干预措施:病例报告
IF 1.7 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-06-23 DOI: 10.1016/j.jaim.2024.100912
Ankita Abhijeet Shirkande , Madhuri Pawar , Abhijeet Sarjerao Shirkande , Gunvant Yeola

Women suffer from various conditions related to menstrual cycle due to changing lifestyle, bad food habits, physical and mental stress. Pre Menstrual Syndrome (PMS) is a combination of physical and emotional symptoms that many women get one or two weeks before the start of their menstrual period. In the present study, 14 years old female patient having symptoms-lower abdominal pain, backache, breast tenderness, constipation, pimples, tiredness and unexplained anger typically in luteal phase from last 4 months, was diagnosed with mild to moderate symptoms of PMS. After proper analysis, she was suggested to consume light to digest dietary articles advised in classical texts for minimizing specific symptoms during menstruation.Thus Green gram Soup and Barley porridge was prescribed to her as lunch and dinner respectively for first three days of menstruation cycle for continuous 6 cycles. It is observed that consumption of these dietary products during the menstruation time period assisted to minimize the symptoms of PMS. This illustrates that there is a wide scope to explore the ayurvedic dietary regimen recommended during menstruation which can be used more rationally to suit menstrual disorders.

由于生活方式的改变、不良的饮食习惯、身体和精神压力,女性会出现各种与月经周期有关的症状。经前期综合征(PMS)是许多妇女在月经来潮前一、两周出现的身体和情绪症状的综合征。在本研究中,14 岁的女患者在过去 4 个月中出现下腹痛、背痛、乳房胀痛、便秘、丘疹、疲倦和不明原因的愤怒等症状,典型的黄体期症状,被诊断为轻度至中度经前综合征症状。经过适当分析后,医生建议她食用古典书籍中建议的清淡易消化的食物,以减少月经期间的特殊症状。因此,医生给她开了绿克汤和大麦粥,分别作为月经周期前三天的午餐和晚餐,连续服用 6 个周期。据观察,在月经期间食用这些食品有助于减轻经前综合症的症状。这说明,经期推荐的阿育吠陀膳食疗法还有很大的探索空间,可以更合理地用于治疗月经紊乱。
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引用次数: 0
Diffuse systemic sclerosis managed with ayurvedic treatment modalities - A case report. 用阿育吠陀疗法治疗弥漫性系统性硬化症--病例报告。
IF 2.4 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-05-16 DOI: 10.1016/j.jaim.2023.100883
Ranjani Karthik Pandit

Diffuse systemic sclerosis or scleroderma is a chronic connective tissue disorder involving many systems and visceral organs. The association of interstitial lung disease carries high mortality risk. This is a case report of a patient aged 25-years, who was diagnosed as diffuse systemic sclerosis, a disease complex along with Interstitial Lung Disease (ILD), sclerodactyly. She also presented with digital ulcers and calcium deposits in the ulcers. The symptomatology was understood by analysing the dosha predominance and the composition of the different qualities of each dosha in the patient. This complicated case with a bad prognosis was managed with Ayurvedic treatment procedures and medicines. Matrabasti (medicated enema) with mahamasha taila and dhanvantara taila was given. yogabasti with dashamoola ksheera paka, dhanvantara taila and madhu (decoctive enema), along with other palliative medicines like rasna yoga raja, Yogendra rasa, vasakasava, drakshadi paka, kaishora guggulu, raktapachakaghana vati and Mahatiktaka ghrita were given to the patient. After 1-1.2 years of continuous treatments, patient started showing gradual changes in her health condition. Relief from joint pains, intake of normal food, weight gain, re-establishment of menstruation, healing of ulcers was some of the changes seen in the patient. This case report summaries the effective management of diffuse systemic sclerosis after deducing the complex disease structure to dosa and guna involved and treated by adopting ayurvedic medicine and treatment procedures.

弥漫性系统性硬化症或硬皮病是一种慢性结缔组织疾病,涉及多个系统和内脏器官。与间质性肺部疾病相关的死亡率很高。这是一份 25 岁患者的病例报告,她被诊断为弥漫性系统性硬化症,这是一种与间质性肺病(ILD)和硬皮病并存的复合疾病。她还出现了数字溃疡和溃疡中的钙沉积。通过分析患者体内的 "道"(dosha)占主导地位以及每种 "道"(dosha)不同性质的组成,我们了解了患者的症状。对这一预后不良的复杂病例采用了阿育吠陀治疗程序和药物进行治疗。患者接受了含有 mahamasha taila 和 dhanvantara taila 的 Matrabasti(药物灌肠),含有 dashamoola ksheera paka、dhanvantara taila 和 madhu(煎药灌肠)的 yogabasti,以及其他缓和药物,如 rasna yoga raja、Yogendra rasa、vasakasava、drakshadi paka、kaishora guggulu、raktapachakaghana vati 和 Mahatiktaka ghrita。经过 1-1.2 年的持续治疗,患者的健康状况开始逐渐发生变化。患者的关节疼痛缓解,可以进食正常食物,体重增加,月经恢复,溃疡愈合,这些都是患者身上出现的一些变化。本病例报告总结了弥漫性系统性硬化症的有效治疗方法,通过对复杂的疾病结构进行推断,得出了涉及多沙和古纳的病因,并采用阿育吠陀医学和治疗程序进行治疗。
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引用次数: 0
An immediate pain relief with Agnikarma therapy for acute episode of migraine headache—a case report 用阿格尼卡玛疗法治疗偏头痛急性发作可立即缓解疼痛--病例报告。
IF 1.7 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-05-01 DOI: 10.1016/j.jaim.2024.100953
Praveen Balakrishnan, Emy S. Surendran, Lisha S. Raj

A 58-year-old non-diabetic, non-hypertensive, non-dyslipidemic, euthyroid lady with a known case of migraine for last 10 years approached our hospital complaining of a severe right-sided throbbing headache in the temple area and behind the right ear for three days. She approached our hospital as she did not get any relief from painkillers. An intensity of 10 was recorded on Visual Analogue Scale (VAS) and 8 on the Global Assessment of Migraine Severity (GAMS) Scale. The case was diagnosed to be vatika shirashula on ardhavabhedaka, with no pitta-rakta association. She was posted for Agnikarma therapy [AGT]. Immediately, within 2 min of application of AGT on her right temple, her intense pain reduced, and within 5 min she had no pain [zero on VAS scale and one on GAMS scale]. Samyak mamsa dagdha lakshana was achieved. AGT was tolerable and did not produce any major discomforts. No adverse effects were reported. Patient experienced a mild burning sensation over the AGT, and the blackish discoloration due to AGT faded off within 41 days. AGT could be used as a potent, cheap, fast-acting, adverse effect free emergency treatment for acute attacks of migraine headache.

一位 58 岁的非糖尿病、非高血压、非血脂异常、甲状腺功能正常的女士来我院就诊,她患有偏头痛已有 10 年之久,主诉右侧太阳穴部位和右耳后出现严重的跳动性头痛,已持续三天。由于服用止痛药后症状没有缓解,她来到我院就诊。根据视觉模拟量表(VAS)和偏头痛严重程度全球评估量表(GAMS)的记录,偏头痛的严重程度分别为 10 和 8。该病例被诊断为 vatika shirashula on ardhavabhedaka,没有 pitta-rakta 关联。她被安排接受阿格尼卡玛疗法[AGT]。在她的右太阳穴上涂抹 AGT 后 2 分钟内,她的剧烈疼痛立即减轻,5 分钟内她就不疼了[VAS 评分为 0,GAMS 评分为 1]。三昧金刚 "得以实现。AGT 是可以忍受的,不会产生任何重大不适。无不良反应报告。患者在 AGT 上有轻微的灼烧感,AGT 导致的黑色色斑在 41 天内逐渐消失。AGT 可作为一种强效、廉价、起效快、无不良反应的偏头痛急性发作紧急治疗药物。
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引用次数: 0
IF 2.4 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-05-01 DOI: 10.1016/j.jaim.2024.100910
M.K. Deepthi, A.S. Deepak, Rajni Sharma
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引用次数: 0
Chronic subdural hematoma treated with homeopathic medicine Hamamelis virginica: A case report 用顺势疗法药物金缕梅治疗慢性硬膜下血肿:病例报告
IF 2.4 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-05-01 DOI: 10.1016/j.jaim.2024.100928
Baidurjya Bhattacharjee , Abhijit Dutta

Chronic Subdural Hematoma is a prevalent neurosurgical disorder associated with old age, often resulting from trauma. The condition has limited scope for conservative management, and invasive techniques are frequently used as preferred treatment. Complications often arise due to comorbidities associated with old age. This case details the treatment of the condition in a 71-year-old patient who presented with seizures, hemiparesis, tremor, and disorientation. The patient had a history of a fall a few weeks prior. Initially, the condition was managed through surgery, but recurrence occurred, accompanied by concurrent neurological signs. The patient was subsequently treated with Hamamelis virginica 200CH through homeopathic approach. Following this treatment, the patient returned to his previous state within seven days. No recurrence was observed during the three-month follow-up. This case underscores a positive role of homeopathic medicines in managing neurosurgical conditions such as subdural hematoma. The positive outcomes of this study provide preliminary evidence that may eventually contribute to the design of appropriate clinical trials.

慢性硬膜下血肿是一种常见的神经外科疾病,与老年病有关,通常由外伤引起。这种疾病的保守治疗范围有限,通常采用侵入性技术作为首选治疗方法。并发症往往是由于老年合并症引起的。本病例详细介绍了一名 71 岁患者的治疗情况,该患者出现癫痫发作、偏瘫、震颤和定向障碍。患者曾在几周前摔倒。起初,患者接受了手术治疗,但病情复发,并伴有神经系统症状。随后,患者接受了金缕梅 200CH 顺势疗法治疗。治疗后,患者在七天内恢复了之前的状态。在三个月的随访中没有发现复发。本病例强调了顺势疗法药物在治疗硬膜下血肿等神经外科疾病中的积极作用。这项研究的积极成果提供了初步证据,最终可能有助于设计适当的临床试验。
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引用次数: 0
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Journal of Ayurveda and Integrative Medicine
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