Chronic Kidney Disease (CKD) affects 13.4 % of the global population. Patients with End-Stage Renal Disease (ESRD) needing kidney transplant surgery are estimated between 4.902 and 7.083 million globally as of 2019 in India, which remains unaffordable for most of the population. This case study highlights a CKD G5 male patient undergoing hemodialysis weekly twice for two months, previously advised for transplant. The patient approached P D Patel Ayurveda Hospital, Nadiad, India, for treatment. Presented with puffiness on the face, breathlessness, muscle cramps, appetite loss, bilateral pedal edema, and occasional nausea and vomiting. Before Ayurvedic treatment, his serum creatinine level remained 12 mg/dL even with hemodialysis twice a week, which has been reduced up to 2.1 mg/dL, and blood urea reduced significantly, hemoglobin increased from 9.7 gms% to 14 gms%, and eGFR increased from 5 mL/min per 1.73 m2 to 34.8 mL/min per 1.73 m2. After the treatment, the patient is asymptomatic. This improvement is stable even after discontinuing all the medications except antihypertensive for two years. Following the treatment, dialysis was completely stopped, and the patient no longer required hemodialysis or a kidney transplant. This case provides new insight into the potential of traditional Ayurvedic treatments to manage advanced CKD, offering a cost-effective alternative to dialysis and transplantation.
{"title":"Breaking the dependency cycle: A case report on successfully managed hemodialysis dependent chronic kidney disease with Ayurvedic treatment","authors":"Kaushal Patel , Kalapi Patel , Manish Patel , Chintan Bhatt , Mansi Patel","doi":"10.1016/j.jaim.2025.101177","DOIUrl":"10.1016/j.jaim.2025.101177","url":null,"abstract":"<div><div>Chronic Kidney Disease (CKD) affects 13.4 % of the global population. Patients with End-Stage Renal Disease (ESRD) needing kidney transplant surgery are estimated between 4.902 and 7.083 million globally as of 2019 in India, which remains unaffordable for most of the population. This case study highlights a CKD G5 male patient undergoing hemodialysis weekly twice for two months, previously advised for transplant. The patient approached P D Patel Ayurveda Hospital, Nadiad, India, for treatment. Presented with puffiness on the face, breathlessness, muscle cramps, appetite loss, bilateral pedal edema, and occasional nausea and vomiting. Before Ayurvedic treatment, his serum creatinine level remained 12 mg/dL even with hemodialysis twice a week, which has been reduced up to 2.1 mg/dL, and blood urea reduced significantly, hemoglobin increased from 9.7 gms% to 14 gms%, and eGFR increased from 5 mL/min per 1.73 m<sup>2</sup> to 34.8 mL/min per 1.73 m<sup>2</sup>. After the treatment, the patient is asymptomatic. This improvement is stable even after discontinuing all the medications except antihypertensive for two years. Following the treatment, dialysis was completely stopped, and the patient no longer required hemodialysis or a kidney transplant. This case provides new insight into the potential of traditional Ayurvedic treatments to manage advanced CKD, offering a cost-effective alternative to dialysis and transplantation.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 6","pages":"Article 101177"},"PeriodicalIF":1.9,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145300847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-14DOI: 10.1016/j.jaim.2025.101183
Ranjith Kumar kora, Praveen Kumar Madikonda, Bura Johar
Inflammatory Bowel Disease (IBD) and sarcoidosis are both chronic inflammatory disorders which in some rare instance can co-exist. The treatment with conventional medicines such as sulfasalazine, mesalamine, and steroids is challenge to patients and may not alleviate the disease completely. Ayurvedic treatments in this regard are often revolutionary and help in compressive management of all symptoms. We present a report of a 40-year-old male with IBD, diagnosed with sarcoidosis having abdominal pain, diarrhoea, and significant weight loss. Dadimadi Ghrita, Matra Basti and modified Piccha Basti were the line of treatment aimed at treating gastrointestinal inflammation and restoring normal bowel functions. The treatments improved the imbalance of Vata and Pitta doshas, that can effectively treat Pittadhik Vata Grahani. The effects of treatment was analysed by stool examination, weight gain and biomarkers useful to assess gastrointestinal health and disease (faecal calprotectin and faecal elastase).
{"title":"Basti treatment improved faecal calprotectin and faecal elastase of a patient of inflammatory bowel disease with sarcoidosis - a case report","authors":"Ranjith Kumar kora, Praveen Kumar Madikonda, Bura Johar","doi":"10.1016/j.jaim.2025.101183","DOIUrl":"10.1016/j.jaim.2025.101183","url":null,"abstract":"<div><div>Inflammatory Bowel Disease (IBD) and sarcoidosis are both chronic inflammatory disorders which in some rare instance can co-exist. The treatment with conventional medicines such as sulfasalazine, mesalamine, and steroids is challenge to patients and may not alleviate the disease completely. Ayurvedic treatments in this regard are often revolutionary and help in compressive management of all symptoms. We present a report of a 40-year-old male with IBD, diagnosed with sarcoidosis having abdominal pain, diarrhoea, and significant weight loss. <em>Dadimadi Ghrita, Matra Basti</em> and modified <em>Piccha Basti</em> were the line of treatment aimed at treating gastrointestinal inflammation and restoring normal bowel functions. The treatments improved the imbalance of <em>Vata</em> and <em>Pitta</em> doshas, that can effectively treat <em>Pittadhik Vata Grahani</em>. The effects of treatment was analysed by stool examination, weight gain and biomarkers useful to assess gastrointestinal health and disease (faecal calprotectin and faecal elastase).</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 6","pages":"Article 101183"},"PeriodicalIF":1.9,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145300811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-13DOI: 10.1016/j.jaim.2025.101185
Priyanka A. Dorage, Ashish A. Thatere, Rohini S. Prabhale
Haglund's deformity is one of the orthopedic problematic conditions manifest as a painful plantar heel. Haglund's deformity is a posterosuperior calcaneal projection of bony overgrowth from calcaneum bone which occurs when the foot is exposed to constant strain leading to calcium deposition in the heel bone, can be correlated with Vatakantaka in Ayurveda. It can be treated with a combination of Viddhakarma (therapeutic needle-piercing therapy), and Agnikarma (therapeutic heat therapy) with oral Ayurvedic medications which cure disease and provide long-term relief. A 48-year-old female came with complaints of difficulty in walking, pain in the left heel region which aggravates after awakening in the morning, standing long time, and after excessive walking. She had taken analgesics, and steroids drug for 8 months but didn't get relief. So, she opted for an Ayurvedic medication for further treatment. With the help of seven settings of Viddhakarma, and Agnikarma there was a significant improvement in clinical features, assessment scales of pain, function, swelling, tenderness, and in bony outgrowth. Viddhakarma and Agnikarma an easy, affordable, and straightforward techniques that may be carried out at the OPD level with basic facilities. It can be inferred from this case study that the Combination of Viddhakarma, Agnikarma with oral Ayurvedic drugs is an effective treatment modality for Haglund's deformity.
{"title":"Ayurvedic management of Haglund's deformity diagnosed as Vatakantaka - A case report","authors":"Priyanka A. Dorage, Ashish A. Thatere, Rohini S. Prabhale","doi":"10.1016/j.jaim.2025.101185","DOIUrl":"10.1016/j.jaim.2025.101185","url":null,"abstract":"<div><div>Haglund's deformity is one of the orthopedic problematic conditions manifest as a painful plantar heel. Haglund's deformity is a posterosuperior calcaneal projection of bony overgrowth from calcaneum bone which occurs when the foot is exposed to constant strain leading to calcium deposition in the heel bone, can be correlated with <em>Vatakantaka</em> in Ayurveda. It can be treated with a combination of <em>Viddhakarma</em> (therapeutic needle-piercing therapy), and <em>Agnikarma</em> (therapeutic heat therapy) with oral Ayurvedic medications which cure disease and provide long-term relief. A 48-year-old female came with complaints of difficulty in walking, pain in the left heel region which aggravates after awakening in the morning, standing long time, and after excessive walking. She had taken analgesics, and steroids drug for 8 months but didn't get relief. So, she opted for an Ayurvedic medication for further treatment. With the help of seven settings of <em>Viddhakarma</em>, and <em>Agnikarma</em> there was a significant improvement in clinical features, assessment scales of pain, function, swelling, tenderness, and in bony outgrowth. <em>Viddhakarma</em> and <em>Agnikarma</em> an easy, affordable, and straightforward techniques that may be carried out at the OPD level with basic facilities. It can be inferred from this case study that the Combination of <em>Viddhakarma, Agnikarma</em> with oral Ayurvedic drugs is an effective treatment modality for Haglund's deformity.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 6","pages":"Article 101185"},"PeriodicalIF":1.9,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145292264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-11DOI: 10.1016/j.jaim.2025.101205
Sanjeev Rastogi , Krishna Gopal Sharma
Lower back pain radiating down to lower limbs has been a common clinical entity. This is one prominent reason for absenteeism from workplace leading to loss of work hours and reduced productivity. It is often treated symptomatically and warrants for a disc related surgery if alarming signs pertaining to compressive neuropathy prompt so. Conservative management from Ayurveda is seen to offer good responses in cases where severe locomotor debility persists and warrants for spinal surgery. A young girl diagnosed for lumber spine annular tear and radiculopathy through MRI and having Oswestry Disability Index (ODI) 66 % corresponding to severe disability was treated through whole system Ayurveda management for one year and recovered completely. This case report proposes that Ayurveda whole system management in cases of prolapse intervertebral disc disease with radiculopathy can provide a sustained clinical relief also reflected through radiological investigations.
{"title":"Ayurvedic conservative management of lumber disc disease with annular tear and radiculopathy leading to complete clinical recovery - A case report","authors":"Sanjeev Rastogi , Krishna Gopal Sharma","doi":"10.1016/j.jaim.2025.101205","DOIUrl":"10.1016/j.jaim.2025.101205","url":null,"abstract":"<div><div>Lower back pain radiating down to lower limbs has been a common clinical entity. This is one prominent reason for absenteeism from workplace leading to loss of work hours and reduced productivity. It is often treated symptomatically and warrants for a disc related surgery if alarming signs pertaining to compressive neuropathy prompt so. Conservative management from Ayurveda is seen to offer good responses in cases where severe locomotor debility persists and warrants for spinal surgery. A young girl diagnosed for lumber spine annular tear and radiculopathy through MRI and having Oswestry Disability Index (ODI) 66 % corresponding to severe disability was treated through whole system Ayurveda management for one year and recovered completely. This case report proposes that Ayurveda whole system management in cases of prolapse intervertebral disc disease with radiculopathy can provide a sustained clinical relief also reflected through radiological investigations.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 6","pages":"Article 101205"},"PeriodicalIF":1.9,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145269962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-11DOI: 10.1016/j.jaim.2025.101228
Sandesh Kumar, Sukanya Bhat
Snake bites pose a major public health challenge worldwide, with significant morbidity and mortality. Non-healing ulcers are common in snakebite survivors, often resulting in chronic pain, infection, necrosis, and, in severe cases, amputation. This case study discusses the Ayurvedic treatment of a non-healing ulcer following a viper bite in a 63-year-old woman. The treatment protocol included Vrana Prakshalana (ulcer washing), Pariseka (irrigation), and Bandha (bandaging) with medicated oils and pastes, along with oral traditional formulations like Gandhaka Rasayana and Mahamanjishtadi kashaya. Over four months, the patient experienced complete ulcer healing, pain reduction, and resolution of edema, illustrating the effectiveness of Ayurvedic therapies in addressing complex post-snakebite complications and preventing further issues. This case underscores Ayurveda's potential in managing chronic, treatment-resistant wounds.
{"title":"Ayurvedic management of persistent ulcers after snakebite – A case report","authors":"Sandesh Kumar, Sukanya Bhat","doi":"10.1016/j.jaim.2025.101228","DOIUrl":"10.1016/j.jaim.2025.101228","url":null,"abstract":"<div><div>Snake bites pose a major public health challenge worldwide, with significant morbidity and mortality. Non-healing ulcers are common in snakebite survivors, often resulting in chronic pain, infection, necrosis, and, in severe cases, amputation. This case study discusses the Ayurvedic treatment of a non-healing ulcer following a viper bite in a 63-year-old woman. The treatment protocol included <em>Vrana Prakshalana</em> (ulcer washing), <em>Pariseka</em> (irrigation), and <em>Bandha</em> (bandaging) with medicated oils and pastes, along with oral traditional formulations like <em>Gandhaka Rasayana</em> and <em>Mahamanjishtadi kashaya</em>. Over four months, the patient experienced complete ulcer healing, pain reduction, and resolution of edema, illustrating the effectiveness of Ayurvedic therapies in addressing complex post-snakebite complications and preventing further issues. This case underscores Ayurveda's potential in managing chronic, treatment-resistant wounds.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 6","pages":"Article 101228"},"PeriodicalIF":1.9,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145279943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-27DOI: 10.1016/j.jaim.2025.101243
Aqsa Zarin Khan , Jibi Varghese , Chandrakumar Deshmukh , Prashant Khade , Sana Khanam Mirza , Manna Mathew
Persistent Depressive Disorder (PDD), formerly known as Dysthymia, is a chronic and enduring form of depression. In contemporary society, the pressures of modern lifestyles, pervasive feelings of uncertainty and insecurity, the fast pace of life, competition in various domains, suboptimal hygiene practices, and food adulteration have become primary contributors to the disruption of mental and physical well-being. Persistent Depressive Disorder (PDD) can be correlated to Vishada in Ayurveda. This article presents a case study of a patient diagnosed with PDD (Persistent Depressive Disorder) as per DSM-5 criteria. Management was planned with integrative treatment consisting of Sattvavajaya chikitsa (Ayurveda psychotherapy), Shamana Chikitsa (oral medicines), and the skillful implementation of Viddhakarma, thus illustrating its efficacy in depression. The treatment persisted for six months, and the intervention outcome demonstrated a decrease in Hamilton Depression Rating scores, declining from 16 to 5 with a reduction of symptoms by the end of the six months of intervention. Viddhakarma, one among the eight shastra karma, is regarded as one of the most effective para-surgical procedures for regulating the vitiated dosha described by Acharya Shushrut and Acharya Vagbhata. This article is a sincere effort to emphasize the significance and application of Viddhakarma therapy along with the conventional Ayurveda treatment in manasik vikaras. Furthermore, the observed improvements were sustained even throughout the non-interventional observation period.
{"title":"A holistic Ayurvedic approach to manage persistent depressive disorder, Vishada—A case report","authors":"Aqsa Zarin Khan , Jibi Varghese , Chandrakumar Deshmukh , Prashant Khade , Sana Khanam Mirza , Manna Mathew","doi":"10.1016/j.jaim.2025.101243","DOIUrl":"10.1016/j.jaim.2025.101243","url":null,"abstract":"<div><div>Persistent Depressive Disorder (PDD), formerly known as Dysthymia, is a chronic and enduring form of depression. In contemporary society, the pressures of modern lifestyles, pervasive feelings of uncertainty and insecurity, the fast pace of life, competition in various domains, suboptimal hygiene practices, and food adulteration have become primary contributors to the disruption of mental and physical well-being. Persistent Depressive Disorder (PDD) can be correlated to <em>Vishada</em> in Ayurveda. This article presents a case study of a patient diagnosed with PDD (Persistent Depressive Disorder) as per DSM-5 criteria. Management was planned with integrative treatment consisting of <em>Sattvavajaya chikitsa</em> (Ayurveda psychotherapy), <em>Shamana Chikitsa</em> (oral medicines), and the skillful implementation of <em>Viddhakarma,</em> thus illustrating its efficacy in depression. The treatment persisted for six months, and the intervention outcome demonstrated a decrease in Hamilton Depression Rating scores, declining from 16 to 5 with a reduction of symptoms by the end of the six months of intervention. <em>Viddhakarma</em>, one among the eight <em>shastra karma</em>, is regarded as one of the most effective para-surgical procedures for regulating the vitiated <em>dosha</em> described by <em>Acharya</em> Shushrut and <em>Acharya</em> Vagbhata. This article is a sincere effort to emphasize the significance and application of <em>Viddhakarma</em> therapy along with the conventional Ayurveda treatment in <em>manasik vikaras</em>. Furthermore, the observed improvements were sustained even throughout the non-interventional observation period.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 6","pages":"Article 101243"},"PeriodicalIF":1.9,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145157265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daruharidra/Maramanjal is one of the most popular shrub used in Ayurveda, Siddha and other Indian medicinal systems. More than one botanical source is traded under this name, predominantly Berberis aristata and Coscinium fenestratum with an annual trade of 1000–2000 metric tonnes. The herbal drug trade is often reported with misidentification, adulteration and/or substitution issues due to morphological resemblance and confusion in vernacular names. This work aimed to integrate macro-microscopic, DNA marker strategies and phytochemical assay to differentiate Berberis aristata from its traded sources.
Material and methods
Thirteen marketed samples and one authentic field sample from natural habitat were collected from various regions of the Indian market under the trade name Maramanjal/Daruharidra. The traditional identification methods included macro-microscopic and phytochemical screening by High-Performance Thin Layer Chromatography (HPTLC). Additionally, DNA barcode-based molecular identification and phylogenetic analysis were done using the ITS2 (Internal Transcribed Spacer 2) marker.
Results
The macroscopic observations revealed 80 % ad-mixing of various allied botanicals in addition to accepted north Indian and south Indian sources such as B. aristata and C. fenestratum respectively. DNA barcoding enabled the identification of genuine and adulterated raw drugs from the collected samples. The HPTLC quantification revealed the presence of berberine in all 14 samples varying from 1.12 % to 26.33 %.
Conclusions
The macro-micro, HPTLC, and DNA barcoding helped in the identification of adulteration and substitution practices in this highly traded botanical drug. DNA barcoding can prove an effective tool for discovering the adulteration and substitution of Maramanjal/Daruharidra and this is its first report on the application of morphology, microscopy, phytochemical analysis, and DNA markers in differentiating these traded species.
{"title":"Integrating macro-microscopy, DNA barcoding and HPTLC for quality assessment of berberine containing botanicals traded as Maramanjal/Daruharidra","authors":"Sunil Kumar Koppala Narayana , Pushkar Kaira , Mahima Karthikeyan , Murugammal Shanmugam , Susikumar Sundharamoorthy , Remya Andalil , Divya Kallingil Gopi , Radha Prakasam , Shakila Ramachandran , Kanagarajan Arumugam","doi":"10.1016/j.jaim.2025.101192","DOIUrl":"10.1016/j.jaim.2025.101192","url":null,"abstract":"<div><h3>Background</h3><div><em>Daruharidra/Maramanjal</em> is one of the most popular shrub used in Ayurveda, Siddha and other Indian medicinal systems. More than one botanical source is traded under this name, predominantly <em>Berberis aristata</em> and <em>Coscinium fenestratum</em> with an annual trade of 1000–2000 metric tonnes. The herbal drug trade is often reported with misidentification, adulteration and/or substitution issues due to morphological resemblance and confusion in vernacular names. This work aimed to integrate macro-microscopic, DNA marker strategies and phytochemical assay to differentiate <em>Berberis aristata</em> from its traded sources.</div></div><div><h3>Material and methods</h3><div>Thirteen marketed samples and one authentic field sample from natural habitat were collected from various regions of the Indian market under the trade name <em>Maramanjal/Daruharidra</em>. The traditional identification methods included macro-microscopic and phytochemical screening by High-Performance Thin Layer Chromatography (HPTLC). Additionally, DNA barcode-based molecular identification and phylogenetic analysis were done using the ITS2 (Internal Transcribed Spacer 2) marker.</div></div><div><h3>Results</h3><div>The macroscopic observations revealed 80 % ad-mixing of various allied botanicals in addition to accepted north Indian and south Indian sources such as <em>B. aristata</em> and <em>C. fenestratum</em> respectively. DNA barcoding enabled the identification of genuine and adulterated raw drugs from the collected samples. The HPTLC quantification revealed the presence of berberine in all 14 samples varying from 1.12 % to 26.33 %.</div></div><div><h3>Conclusions</h3><div>The macro-micro, HPTLC, and DNA barcoding helped in the identification of adulteration and substitution practices in this highly traded botanical drug. DNA barcoding can prove an effective tool for discovering the adulteration and substitution of <em>Maramanjal/Daruharidra</em> and this is its first report on the application of morphology, microscopy, phytochemical analysis, and DNA markers in differentiating these traded species.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 5","pages":"Article 101192"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01DOI: 10.1016/j.jaim.2025.101273
Girish Tillu
{"title":"Pedagogy experiments for Ayush academia","authors":"Girish Tillu","doi":"10.1016/j.jaim.2025.101273","DOIUrl":"10.1016/j.jaim.2025.101273","url":null,"abstract":"","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 5","pages":"Article 101273"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01DOI: 10.1016/j.jaim.2025.101189
Vipin K. Rathore, Sandeep Singh, Nidheesh Yadav
This study aims to investigate the impact of yoga practice on pulmonary and respiratory functions in clinical populations. A thorough search was carried out in the Cochrane Library, PubMed, Science Direct databases, and Google Scholar, using the keywords “Yog∗” and “pulmonary functions”, covering the period from January 2010 to December 2022. Studies that aligned with PRISMA recommendations were included. The Cochrane risk-assessment tool was employed to assess bias risk. We calculated weighted mean differences (WMDs) with 95 % confidence intervals (CIs) and used the I2 test to assess heterogeneity. Initially, 529 studies were found through the search, with 10 randomized controlled trials (RCTs) involving 1007 patients meeting the inclusion criteria for quality assessment and meta-analysis. The results indicated that yoga intervention (YI) significantly improved FVC% (WMD: 3.03 L, 95 % CI: 1.71, 4.35, P < 0.00001), FEV1 (WMD: 0.47 L, 95 % CI: 0.43, 0.51, P < 0.00001), and FEV1% (WMD: 5.74 L, 95 % CI: 4.47, 7.01, P < 0.00001) when compared to control groups. However, no significant effect was observed on FVC (WMD: 0.23 L, CI: 0.16, 0.62. P = 0.25), PEFR (WMD: 0.49, CI: 0.70, 1.67, P = 0.42), MVV (WMD: 9.01, CI: 3.92, 21.94, P = 0.17), and FEV1/FVC (WMD: 3.17, CI: 1.15, 7.48, P = 0.15) as a result of YI. Based on the limited evidence and meta-analysis conducted, YI demonstrated a positive effect on pulmonary function in clinical populations and could be considered as an adjunct therapy for individuals with various respiratory diseases. Further rigorous research with larger sample sizes is necessary to confirm the long-term benefits of yoga.
{"title":"Impact of yoga on pulmonary functions in clinical population: A systematic review and meta-analysis of randomized controlled trials (RCTs)","authors":"Vipin K. Rathore, Sandeep Singh, Nidheesh Yadav","doi":"10.1016/j.jaim.2025.101189","DOIUrl":"10.1016/j.jaim.2025.101189","url":null,"abstract":"<div><div>This study aims to investigate the impact of yoga practice on pulmonary and respiratory functions in clinical populations. A thorough search was carried out in the Cochrane Library, PubMed, Science Direct databases, and Google Scholar, using the keywords “Yog∗” and “pulmonary functions”, covering the period from January 2010 to December 2022. Studies that aligned with PRISMA recommendations were included. The Cochrane risk-assessment tool was employed to assess bias risk. We calculated weighted mean differences (WMDs) with 95 % confidence intervals (CIs) and used the I<sup>2</sup> test to assess heterogeneity. Initially, 529 studies were found through the search, with 10 randomized controlled trials (RCTs) involving 1007 patients meeting the inclusion criteria for quality assessment and meta-analysis. The results indicated that yoga intervention (YI) significantly improved FVC% (WMD: 3.03 L, 95 % CI: 1.71, 4.35, P < 0.00001), FEV1 (WMD: 0.47 L, 95 % CI: 0.43, 0.51, P < 0.00001), and FEV1% (WMD: 5.74 L, 95 % CI: 4.47, 7.01, P < 0.00001) when compared to control groups. However, no significant effect was observed on FVC (WMD: 0.23 L, CI: 0.16, 0.62. P = 0.25), PEFR (WMD: 0.49, CI: 0.70, 1.67, P = 0.42), MVV (WMD: 9.01, CI: 3.92, 21.94, P = 0.17), and FEV1/FVC (WMD: 3.17, CI: 1.15, 7.48, P = 0.15) as a result of YI. Based on the limited evidence and meta-analysis conducted, YI demonstrated a positive effect on pulmonary function in clinical populations and could be considered as an adjunct therapy for individuals with various respiratory diseases. Further rigorous research with larger sample sizes is necessary to confirm the long-term benefits of yoga.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 5","pages":"Article 101189"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144996896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This case report is the description of a devastating illness, Progressive Bulbar Palsy (PBP) of a sixty-seven years old male patient. He presented with complaints of slurred speech, hearing impairment, generalised weakness of limbs, weakened grip to hold objects in hand, difficulty to walk with normal speed, frequent dizzy feeling while walking, severe fatigue, increased anger, heaviness of head, depression, anxiety, decreased memory and headache for 1 year. When he consulted conventional medicine, in Magnetic Resonance Imaging (MRI) of brain, only ‘Partial empty sella’ and age related mild cerebral atrophy was detected and the patient was diagnosed PBP clinically. They prescribed Riluzole 50 mg tablet twice a day and Fluoxetine 10mg capsules at night time for 3 months, but obtained no relief for symptoms and consulted this Out Patient Department (OPD). In Ayurvedic parlance, PBP resembles conditions like Kaphavruta vata. In this patient, Pittavritavata symptoms like bhrama (∼dizziness) was also present in increased severity. Diagnosis was done with the aid of Gold Coast diagnostic criteria. Internal and external medications with properties alleviating avarana (∼occlusion) of vata by kapha and pitta, shodhana (∼expelling the aggravated doshas and cleanses the body internally), rejuvenating (Rasayana) properties, for overall strengthening of nervous system and musculoskeletal system, enhancing balance and coordination, improving speech and memory were used. The assessment was done before and after the treatment by ‘Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R). The score before and after the treatment was 35 and 45 respectively out of 48. The treatment helped to increase the quality of life exceptionally as symptomatic relief was obtained. As it is a devastating disorder with poor prognosis and most probably will lead to death, it is advisable to repeat the treatments in regular intervals, depending on the recurrence of symptoms, if any.
{"title":"A case report on Ayurvedic management of progressive bulbar palsy-A rare amyotrophic lateral sclerosis phenotype","authors":"Sinimol Thekkekkoottumughath Peethambaran , Abhayadev Ashokan , Varanasi Subhose","doi":"10.1016/j.jaim.2025.101176","DOIUrl":"10.1016/j.jaim.2025.101176","url":null,"abstract":"<div><div>This case report is the description of a devastating illness, Progressive Bulbar Palsy (PBP) of a sixty-seven years old male patient. He presented with complaints of slurred speech, hearing impairment, generalised weakness of limbs, weakened grip to hold objects in hand, difficulty to walk with normal speed, frequent dizzy feeling while walking, severe fatigue, increased anger, heaviness of head, depression, anxiety, decreased memory and headache for 1 year. When he consulted conventional medicine, in Magnetic Resonance Imaging (MRI) of brain, only ‘Partial empty sella’ and age related mild cerebral atrophy was detected and the patient was diagnosed PBP clinically. They prescribed Riluzole 50 mg tablet twice a day and Fluoxetine 10mg capsules at night time for 3 months, but obtained no relief for symptoms and consulted this Out Patient Department (OPD). In Ayurvedic parlance, PBP resembles conditions like <em>Kaphavruta vata</em>. In this patient, <em>Pittavritavata</em> symptoms like <em>bhrama</em> (∼dizziness) was also present in increased severity. Diagnosis was done with the aid of Gold Coast diagnostic criteria. Internal and external medications with properties alleviating <em>avarana</em> (∼occlusion) of <em>vata</em> by <em>kapha</em> and <em>pitta</em>, <em>shodhana</em> (∼expelling the aggravated doshas and cleanses the body internally), rejuvenating <em>(Rasayana) properties,</em> for overall strengthening of nervous system and musculoskeletal system, enhancing balance and coordination, improving speech and memory were used. The assessment was done before and after the treatment by ‘Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R). The score before and after the treatment was 35 and 45 respectively out of 48. The treatment helped to increase the quality of life exceptionally as symptomatic relief was obtained. As it is a devastating disorder with poor prognosis and most probably will lead to death, it is advisable to repeat the treatments in regular intervals, depending on the recurrence of symptoms, if any.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 5","pages":"Article 101176"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144996897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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