The use of a carbon fiber composite material to make external prostheses in the form of a femoral socket was the subject of this laboratory study. According to the prior bibliographical studies, this material adapts well to this type of prosthesis. The objective of this research is to study its microscopic structure, in order to verify the good wetting of the fibers by the resin, the good cohesion and molding by infusion. The morphological study of the facies of the parallelepiped-shaped specimens was carried out after cuts perpendicular to the axis of the fiber strands, parallel according to the width and thickness of the specimen. This study was carried out using a scanning electron microscope (SEM), in order to determine, thanks to the typical microstructure of the composite, the various degradations, which appear as a result of the effect of static tension. The laminate used is based on three layers of carbon taffeta fabric and an orthocrylic resin. Tensile tests have been carried out at a speed of 1mm/min with a Zwick/Roell machine with a load cell of 50 kN. This speed was chosen to allow a comparative study with glass fiber specimens, which have been used previously for the production of prostheses, before those made of carbon. The microscopic study allowed to identify the four types of degradation; Matrix fracture, which manifested itself as fault lines, in preferred directions of different sizes. This contributed to interlaminar delamination. The decohesion that contributes to delamination in a different way from that of matrix breakage is visible at different levels. Interlaminar delamination results from the combined effect of matrix breakdown and decohesion and manifests itself as uneven strata. Fiber breakage was manifested by shearing. This study allowed to observing a degradation of the material imposed by static traction. As for the material used in orthopaedics, it has retained good cohesion and meets the requirements of prostheses, despite the defects detected by the microscopic study.
{"title":"Contribution to the Microstructural Study of a Composite Material Based on Carbon Fibers for Use in Orthopedic Prostheses","authors":"Y. Menail, L. Alimi, Sofiane Boudiaf, N. Metrane","doi":"10.4028/p-f5ma5j","DOIUrl":"https://doi.org/10.4028/p-f5ma5j","url":null,"abstract":"The use of a carbon fiber composite material to make external prostheses in the form of a femoral socket was the subject of this laboratory study. According to the prior bibliographical studies, this material adapts well to this type of prosthesis. The objective of this research is to study its microscopic structure, in order to verify the good wetting of the fibers by the resin, the good cohesion and molding by infusion. The morphological study of the facies of the parallelepiped-shaped specimens was carried out after cuts perpendicular to the axis of the fiber strands, parallel according to the width and thickness of the specimen. This study was carried out using a scanning electron microscope (SEM), in order to determine, thanks to the typical microstructure of the composite, the various degradations, which appear as a result of the effect of static tension. The laminate used is based on three layers of carbon taffeta fabric and an orthocrylic resin. Tensile tests have been carried out at a speed of 1mm/min with a Zwick/Roell machine with a load cell of 50 kN. This speed was chosen to allow a comparative study with glass fiber specimens, which have been used previously for the production of prostheses, before those made of carbon. The microscopic study allowed to identify the four types of degradation; Matrix fracture, which manifested itself as fault lines, in preferred directions of different sizes. This contributed to interlaminar delamination. The decohesion that contributes to delamination in a different way from that of matrix breakage is visible at different levels. Interlaminar delamination results from the combined effect of matrix breakdown and decohesion and manifests itself as uneven strata. Fiber breakage was manifested by shearing. This study allowed to observing a degradation of the material imposed by static traction. As for the material used in orthopaedics, it has retained good cohesion and meets the requirements of prostheses, despite the defects detected by the microscopic study.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"58 1","pages":"13 - 23"},"PeriodicalIF":0.7,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49208819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Barkcloth a naturally occurring cellulosic non-woven fabric has recently obtained attention within the scientific community for end use applications in various industries for instance automobile, household furnishing and construction owing to its robust mechanical, thermal and sound absorption properties. In this work, barkcloth was treated with different concentrations of zinc oxide nanoparticles which were deposited with the pad-dry-cure procedure. The Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) were chosen for the evaluation of the anti-microbial efficacy of Zinc oxide Nanoparticles (ZNPs). The coated barkcloth samples with ZNPs concentration 0.6 g/L optimally performed against the two most common resistant bacteria i.e. the gram +ve and gram –ve bacteria, with the gram negative E-coli bacteria demonstrating a high susceptibility to the ZNPs than gram positive S-aureus.
{"title":"Functional Finishing of Barkcloth for Antimicrobial Properties Using Zinc Oxide Nanoparticles","authors":"Samm Okinyi Youma, Samson Rwahwire, Yvonne Tusiimire","doi":"10.4028/p-p0075p","DOIUrl":"https://doi.org/10.4028/p-p0075p","url":null,"abstract":"Barkcloth a naturally occurring cellulosic non-woven fabric has recently obtained attention within the scientific community for end use applications in various industries for instance automobile, household furnishing and construction owing to its robust mechanical, thermal and sound absorption properties. In this work, barkcloth was treated with different concentrations of zinc oxide nanoparticles which were deposited with the pad-dry-cure procedure. The Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) were chosen for the evaluation of the anti-microbial efficacy of Zinc oxide Nanoparticles (ZNPs). The coated barkcloth samples with ZNPs concentration 0.6 g/L optimally performed against the two most common resistant bacteria i.e. the gram +ve and gram –ve bacteria, with the gram negative E-coli bacteria demonstrating a high susceptibility to the ZNPs than gram positive S-aureus.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"58 1","pages":"75 - 79"},"PeriodicalIF":0.7,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44698458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
White blood cell image segmentation provides the opportunity for medical experts to objectively diagnose the medical conditions of patients suffering from Leukemia, for example. Due to the rigorous nature of cell image acquisition (staining process and non-uniform illumination) efficient tools must be deployed to achieve the desired segmentation result. In this paper, a deep learning model is proposed together with a grab cut. The developed deep learning model provides an initial coarse segmentation of white blood cell images. However, the objective of this segmentation is to localize or identify regions of interest from white blood cell images. A bounding is generated from the localized cell image and then used to initiate an automatic cell image segmentation using grab cut. Results of the two publicly available datasets of white blood cell images are considered satisfactory on the proposed model.
{"title":"Leveraging Deep Learning and Grab Cut for Automatic Segmentation of White Blood Cell Images","authors":"K. Oyebode","doi":"10.4028/p-oj4d78","DOIUrl":"https://doi.org/10.4028/p-oj4d78","url":null,"abstract":"White blood cell image segmentation provides the opportunity for medical experts to objectively diagnose the medical conditions of patients suffering from Leukemia, for example. Due to the rigorous nature of cell image acquisition (staining process and non-uniform illumination) efficient tools must be deployed to achieve the desired segmentation result. In this paper, a deep learning model is proposed together with a grab cut. The developed deep learning model provides an initial coarse segmentation of white blood cell images. However, the objective of this segmentation is to localize or identify regions of interest from white blood cell images. A bounding is generated from the localized cell image and then used to initiate an automatic cell image segmentation using grab cut. Results of the two publicly available datasets of white blood cell images are considered satisfactory on the proposed model.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"58 1","pages":"121 - 128"},"PeriodicalIF":0.7,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44970250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. A. Abbod, Shireen H. Challoob, K. K. Resan, Ehsan Omaraa
In this study the effect of adding different weight ratio (0.5, 1, 1.5, 2)% of TiO2 nanoparticles powder extend the life of removable partial dentures made by PMMA was studied.The PMMA has low mechanical properties. Then the life is relatively short. After adding these different weight ratios, it found that the highest ultimate compressive stress was at the weight ratio 1.5% . The chewing force measured using a special sensors F-scan, which represents a mat of micro-sensors.When the value of the chewing pressure was 312 kPa. To measure the life of partial dentures, a special device was manufactured that applied a force that simulated the force generated during chewing . It measured by the f-scan sensor, and the best life of 1.5% TiO2 was added by weight. The lifetime of dentures increased by about 80% after adding 1.5 wt% of TiO2 nanoparticles.
{"title":"Study of the Life of Partial Removable Denture Manufactured by PMMA Reinforced with Nano TiO2","authors":"E. A. Abbod, Shireen H. Challoob, K. K. Resan, Ehsan Omaraa","doi":"10.4028/p-i5yta0","DOIUrl":"https://doi.org/10.4028/p-i5yta0","url":null,"abstract":"In this study the effect of adding different weight ratio (0.5, 1, 1.5, 2)% of TiO2 nanoparticles powder extend the life of removable partial dentures made by PMMA was studied.The PMMA has low mechanical properties. Then the life is relatively short. After adding these different weight ratios, it found that the highest ultimate compressive stress was at the weight ratio 1.5% . The chewing force measured using a special sensors F-scan, which represents a mat of micro-sensors.When the value of the chewing pressure was 312 kPa. To measure the life of partial dentures, a special device was manufactured that applied a force that simulated the force generated during chewing . It measured by the f-scan sensor, and the best life of 1.5% TiO2 was added by weight. The lifetime of dentures increased by about 80% after adding 1.5 wt% of TiO2 nanoparticles.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"58 1","pages":"3 - 12"},"PeriodicalIF":0.7,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47861191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The ability to promote rapid osseointegration is an important criterion on the titanium implant surface. This performance is greatly determined by the roughness, wettability, and composition of the implant surface. This study aims to investigate the oxide layer formation and wettability on the EDM-titanium implant surface engineered by different micro-finishing methods (i.e. mechanical, physical, and chemical processes). The oxide layer formation was investigated by observing the wt% of oxygen formed while the wettability criterion was studied by determining the contact angle between the liquid and solid surface. The result reveals that the oxide layers formed on the sample surface, excepting Sulfuric acid (H2SO4) 95%-etched, show an interaction with the surface roughness and its wettability. The smoother the surface roughness of the sample, the lower the percentage of the oxide layer and the contact angle formed on the sample surface. In this aspect, the ultrasonic cleaning benchmark has the highest percentage by altering 18.84% of the oxide layer formed by the EDM process while the decrease of 75.89% generated by the H2SO4-etching is the lowest one. On the other hand, the higher the percentage of the oxide layer formation, the lower the wettability of the sample surface. In this aspect, the ultrasonic cleaning benchmark has the lowest wettability with a contact angle of 124º (hydrophilic) while HCl-etching is the lowest with 45º (hydrophobic). The results are notable that the ultrasonic cleaning method is able to alter wt% of the oxygen on the EDM-titanium implant surface, whereas the acid etching method can be recommended as a worthy method of the surface finishing for the semi-permanent type of implant.
{"title":"Formation of Oxide Layer and Wettability on the Surface of Electrical Discharge Machining-Based Implant Engineered by Micro-Finishing","authors":"N. Qosim, S. Supriadi","doi":"10.4028/p-8u998r","DOIUrl":"https://doi.org/10.4028/p-8u998r","url":null,"abstract":"The ability to promote rapid osseointegration is an important criterion on the titanium implant surface. This performance is greatly determined by the roughness, wettability, and composition of the implant surface. This study aims to investigate the oxide layer formation and wettability on the EDM-titanium implant surface engineered by different micro-finishing methods (i.e. mechanical, physical, and chemical processes). The oxide layer formation was investigated by observing the wt% of oxygen formed while the wettability criterion was studied by determining the contact angle between the liquid and solid surface. The result reveals that the oxide layers formed on the sample surface, excepting Sulfuric acid (H2SO4) 95%-etched, show an interaction with the surface roughness and its wettability. The smoother the surface roughness of the sample, the lower the percentage of the oxide layer and the contact angle formed on the sample surface. In this aspect, the ultrasonic cleaning benchmark has the highest percentage by altering 18.84% of the oxide layer formed by the EDM process while the decrease of 75.89% generated by the H2SO4-etching is the lowest one. On the other hand, the higher the percentage of the oxide layer formation, the lower the wettability of the sample surface. In this aspect, the ultrasonic cleaning benchmark has the lowest wettability with a contact angle of 124º (hydrophilic) while HCl-etching is the lowest with 45º (hydrophobic). The results are notable that the ultrasonic cleaning method is able to alter wt% of the oxygen on the EDM-titanium implant surface, whereas the acid etching method can be recommended as a worthy method of the surface finishing for the semi-permanent type of implant.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"58 1","pages":"25 - 33"},"PeriodicalIF":0.7,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44022358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clarence Rubaka, J. Gathirwa, H. Malebo, H. Swai, A. Hilonga
Inorganic nanocarriers for a decade have increased interest in nanotechnology research platform as versatile drug delivery materials. The utility of the inorganic nanocarriers for delivery of therapeutic agents is attributed to their unique properties such as magnetic, photocatalytic nature and the ability to exhibit surface functionalization. Herein, we review the surface functionalization and delivery utility for natural therapeutics exhibited by inorganic nanocarriers mostly focusing on their magnetic, photocatalytic and the plasmonic properties. The review also highlights the influence of electronic property of inorganic surface on functionalization of ligand based natural therapeutic agents. Improvement of stability and therapeutic potential by formation of nanocomposites are detailed. Furthermore, we suggest improvement strategies for stability and toxicity reduction of inorganic nanoparticles that would potentially make them useful for clinical application as therapeutic delivery tools for treatment of various diseases.
{"title":"Inorganic Nanocarriers: Surface Functionalization, Delivery Utility for Natural Therapeutics - A Review","authors":"Clarence Rubaka, J. Gathirwa, H. Malebo, H. Swai, A. Hilonga","doi":"10.4028/p-96l963","DOIUrl":"https://doi.org/10.4028/p-96l963","url":null,"abstract":"Inorganic nanocarriers for a decade have increased interest in nanotechnology research platform as versatile drug delivery materials. The utility of the inorganic nanocarriers for delivery of therapeutic agents is attributed to their unique properties such as magnetic, photocatalytic nature and the ability to exhibit surface functionalization. Herein, we review the surface functionalization and delivery utility for natural therapeutics exhibited by inorganic nanocarriers mostly focusing on their magnetic, photocatalytic and the plasmonic properties. The review also highlights the influence of electronic property of inorganic surface on functionalization of ligand based natural therapeutic agents. Improvement of stability and therapeutic potential by formation of nanocomposites are detailed. Furthermore, we suggest improvement strategies for stability and toxicity reduction of inorganic nanoparticles that would potentially make them useful for clinical application as therapeutic delivery tools for treatment of various diseases.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"58 1","pages":"81 - 96"},"PeriodicalIF":0.7,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48734333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Anene, C. Jaafar, I. Zainol, A. H. Mohamed Ariff, S. Mohd Tahir
α + β titanium alloys especially Ti-6Al-4V alloy have dominated implant industry over the years due to their high corrosion resistance, strength, and flexibility. However, their high modulus (110GPa) compared to the human bone (18-30GPa) results in aseptic loosening of implants. Hydroxyapatite (HA) coating on Ti-6Al-4V alloys has been used to mitigate these demerits, nevertheless, more still need to be done. Hence, the present study aims at developing a natural and economical bioceramic coating on low modulus Ti-13Nb-13Zr alloy substrates using plasma spraying technique for biomedical applications. The bioceramic used was natural HA derived from fish scales (FsHA) and FsHA doped yttria stabilized zirconia at (10-20 wt.%). FsHA/YSZ powders and the coated samples were examined by XRD and SEM/EDX and the surface roughness, microhardness and corrosion resistance of the uncoated substrate and coated samples determined. The XRD pattern showed good crystalline FsHA/YSZ powders for all the compositions while the microstructure of the coatings revealed a fine splat lamellar morphology with partially melted and non-melted FsHA particles along with evenly dispersed Zr particles within the coating matrix for the FsHA/YSZ coatings. The maximum surface roughness (4.215 µm) was found with the FsHA coating while FsHA/YSZ coatings presented the highest hardness values (492.5-536.9 Hv) compared to the FsHA coating (467.8 Hv) and the uncoated substrate (385.9 Hv). Similarly, the corrosion resistance of the Ti-13Nb-13Zr alloy was significantly improved with the deposition of FsHA/YSZ bioceramic coatings.
{"title":"Evaluation of Corrosion Inhibition of Plasma Sprayed FsHA/YSZ Coating on β-Titanium (Ti-13Nb-13Zr) Alloy Using Electrochemical Techniques","authors":"F. Anene, C. Jaafar, I. Zainol, A. H. Mohamed Ariff, S. Mohd Tahir","doi":"10.4028/p-6b2uc3","DOIUrl":"https://doi.org/10.4028/p-6b2uc3","url":null,"abstract":"α + β titanium alloys especially Ti-6Al-4V alloy have dominated implant industry over the years due to their high corrosion resistance, strength, and flexibility. However, their high modulus (110GPa) compared to the human bone (18-30GPa) results in aseptic loosening of implants. Hydroxyapatite (HA) coating on Ti-6Al-4V alloys has been used to mitigate these demerits, nevertheless, more still need to be done. Hence, the present study aims at developing a natural and economical bioceramic coating on low modulus Ti-13Nb-13Zr alloy substrates using plasma spraying technique for biomedical applications. The bioceramic used was natural HA derived from fish scales (FsHA) and FsHA doped yttria stabilized zirconia at (10-20 wt.%). FsHA/YSZ powders and the coated samples were examined by XRD and SEM/EDX and the surface roughness, microhardness and corrosion resistance of the uncoated substrate and coated samples determined. The XRD pattern showed good crystalline FsHA/YSZ powders for all the compositions while the microstructure of the coatings revealed a fine splat lamellar morphology with partially melted and non-melted FsHA particles along with evenly dispersed Zr particles within the coating matrix for the FsHA/YSZ coatings. The maximum surface roughness (4.215 µm) was found with the FsHA coating while FsHA/YSZ coatings presented the highest hardness values (492.5-536.9 Hv) compared to the FsHA coating (467.8 Hv) and the uncoated substrate (385.9 Hv). Similarly, the corrosion resistance of the Ti-13Nb-13Zr alloy was significantly improved with the deposition of FsHA/YSZ bioceramic coatings.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"58 1","pages":"45 - 57"},"PeriodicalIF":0.7,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43934150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. V. Nguyen, Gia Quynh Nhu Pham, T. Nguyen, V. Nguyen
Polyphenolic chemicals found in tea leaves are frequently used in pharmaceutics and the food industry. Catechin is a polyphenol that has antimicrobial, antioxidant, and antibacterial effects, as well as other health advantages. The goal of this study was to create a catechin-encapsulated alginate hydrogel (Cate-ALG) that would protect catechin from degradation and bioactivity loss in stressful environments while also delivering catechin. The antioxidant ability of catechin was found to be greater than that of vitamin C using the 2,2-diphenyl-1-pierylhyrazyl assay. The FT-IR spectra revealed the distinct peaks of catechin and alginate. Additionally, due to the hydrogen bond interaction between alginate and catechin molecules, frequency downshifting was observed in the carbonyl and hydroxyl regions. Furthermore, release profile revealed a burst release of 5% catechin-ALG in the first 25 min. On the other hand, the 3% Cate-ALG approached the controlled release profile of catechin and increased the release time by more than 40 minutes. The catechin in alginate hydrogel has the potential for controlled release via transdermal and wound dressing applications.
{"title":"Fabrication and Characterization of Alginate Hydrogels for Control Release System of Catechin-Derived Tea Leave Extract","authors":"V. V. Nguyen, Gia Quynh Nhu Pham, T. Nguyen, V. Nguyen","doi":"10.4028/p-63176q","DOIUrl":"https://doi.org/10.4028/p-63176q","url":null,"abstract":"Polyphenolic chemicals found in tea leaves are frequently used in pharmaceutics and the food industry. Catechin is a polyphenol that has antimicrobial, antioxidant, and antibacterial effects, as well as other health advantages. The goal of this study was to create a catechin-encapsulated alginate hydrogel (Cate-ALG) that would protect catechin from degradation and bioactivity loss in stressful environments while also delivering catechin. The antioxidant ability of catechin was found to be greater than that of vitamin C using the 2,2-diphenyl-1-pierylhyrazyl assay. The FT-IR spectra revealed the distinct peaks of catechin and alginate. Additionally, due to the hydrogen bond interaction between alginate and catechin molecules, frequency downshifting was observed in the carbonyl and hydroxyl regions. Furthermore, release profile revealed a burst release of 5% catechin-ALG in the first 25 min. On the other hand, the 3% Cate-ALG approached the controlled release profile of catechin and increased the release time by more than 40 minutes. The catechin in alginate hydrogel has the potential for controlled release via transdermal and wound dressing applications.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"58 1","pages":"97 - 107"},"PeriodicalIF":0.7,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43655837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There are many requirements for biomaterials used in the applications of bone tissue engineering, besides their biocompatibility, they should exhibit acceptable mechanical properties to mimic bone properties. Many research areas in bioactive materials for bone tissue engineering focused on producing new bioactive glass and ceramic compositions containing a trace of inorganic elements (such as Mg, Sr, Cu, Zn) to combine the mechanical properties and bioactivity. In the present study bioglass-MgO composite material has been used to produce Diopside (CaMgSi2O6) by the sintering process. The compact samples were made from a mixture powder of (7, 15)wt% MgO and binary bioglass 70Si-30Ca sintered at 1100 ᵒC for 2 hr. The XRD results confirmed the presence of diopside and wollastonite CaSiO3 in the case of using 7wt.% MgO while the structure was completely diopside at 15 Wt.% MgO. Physical properties, compressive strength, and hardness were investigated, as well as biodegradation behavior and bioactivity in human saliva were inspected. The results confirmed improving the mechanical properties along with increasing MgO as well as proved the ability to form hydroxyapatite on the surface when exposed to human saliva. These findings demonstrated the positive role of MgO in the mechanical properties of 70Si-30Ca bioactive glass besides producing diopside as a good candidate for hard tissue engineering.
{"title":"Characterizing the Properties of 70Si-30Ca Bioglass-Magnesia Composite as Hard Tissue Replacement Bio-Materials","authors":"I. Sabree, O. Mahdi, F. Shaker, M. Ibrahim","doi":"10.4028/p-74056s","DOIUrl":"https://doi.org/10.4028/p-74056s","url":null,"abstract":"There are many requirements for biomaterials used in the applications of bone tissue engineering, besides their biocompatibility, they should exhibit acceptable mechanical properties to mimic bone properties. Many research areas in bioactive materials for bone tissue engineering focused on producing new bioactive glass and ceramic compositions containing a trace of inorganic elements (such as Mg, Sr, Cu, Zn) to combine the mechanical properties and bioactivity. In the present study bioglass-MgO composite material has been used to produce Diopside (CaMgSi2O6) by the sintering process. The compact samples were made from a mixture powder of (7, 15)wt% MgO and binary bioglass 70Si-30Ca sintered at 1100 ᵒC for 2 hr. The XRD results confirmed the presence of diopside and wollastonite CaSiO3 in the case of using 7wt.% MgO while the structure was completely diopside at 15 Wt.% MgO. Physical properties, compressive strength, and hardness were investigated, as well as biodegradation behavior and bioactivity in human saliva were inspected. The results confirmed improving the mechanical properties along with increasing MgO as well as proved the ability to form hydroxyapatite on the surface when exposed to human saliva. These findings demonstrated the positive role of MgO in the mechanical properties of 70Si-30Ca bioactive glass besides producing diopside as a good candidate for hard tissue engineering.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"58 1","pages":"35 - 44"},"PeriodicalIF":0.7,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43831812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aaron Andrew B. Mutia, R. M. T. Cumba, R. Capangpangan, A. Alguno
Silver nanoparticles were synthesized using locally purchased honey and silver nitrate solution. This method provides a simplistic and straightforward approach to the formation of silver nanoparticles. The silver nanoparticles with varying amounts of silver nitrate solution were characterized using ultraviolet-visible spectroscopy and Fourier transform infrared spectroscopy. In addition, dynamic light scattering characterization was used to determine the average size and size distribution of silver nanoparticles. Experimental results revealed that varying the amount of silver nitrate solution can control the size and absorption spectra of silver nanoparticles. A large amount of silver nitrate solution will exhibit a peak in the higher wavelength. The shifting of the absorption peaks at 401, 406, 407, 408, and 409 nm are believed to be related to the wavelength of the surface plasmon resonance. Moreover, a larger amount of silver nitrate solution also results in an increasing size with 27.2, 57.9, and 63.4 nm as revealed in the size distribution via dynamic light scattering. This green synthesis method of silver nanoparticles will provide a cost-effective production as an alternative to commercial antibacterial agents.
{"title":"Controlling the Particle Size and Absorption Spectra of Honey Mediated Green Synthesis of Silver Nanoparticles for Antibacterial Application","authors":"Aaron Andrew B. Mutia, R. M. T. Cumba, R. Capangpangan, A. Alguno","doi":"10.4028/p-83kcwf","DOIUrl":"https://doi.org/10.4028/p-83kcwf","url":null,"abstract":"Silver nanoparticles were synthesized using locally purchased honey and silver nitrate solution. This method provides a simplistic and straightforward approach to the formation of silver nanoparticles. The silver nanoparticles with varying amounts of silver nitrate solution were characterized using ultraviolet-visible spectroscopy and Fourier transform infrared spectroscopy. In addition, dynamic light scattering characterization was used to determine the average size and size distribution of silver nanoparticles. Experimental results revealed that varying the amount of silver nitrate solution can control the size and absorption spectra of silver nanoparticles. A large amount of silver nitrate solution will exhibit a peak in the higher wavelength. The shifting of the absorption peaks at 401, 406, 407, 408, and 409 nm are believed to be related to the wavelength of the surface plasmon resonance. Moreover, a larger amount of silver nitrate solution also results in an increasing size with 27.2, 57.9, and 63.4 nm as revealed in the size distribution via dynamic light scattering. This green synthesis method of silver nanoparticles will provide a cost-effective production as an alternative to commercial antibacterial agents.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"58 1","pages":"61 - 66"},"PeriodicalIF":0.7,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49616495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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