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Journal of Cardiac Failure最新文献

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Digital Walking Behaviors: Could They Be the “Gait-way” to Monitoring Heart Failure Progression in Community-based Settings? 数字化步行行为--它们能否成为在社区环境中监测心力衰竭进展的 "步态途径"?
IF 6.7 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.cardfail.2024.05.010
WINDY W. ALONSO PhD, RN, FHFSA, FAHA , CHRISTOPHER S. LEE PhD, RN, FHFSA, FAHA, FAAN
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引用次数: 0
Skeletal Muscle Wasting: The Unmeasured “End Organ” in Advanced Heart Failure 骨骼肌萎缩:晚期心力衰竭中无法测量的 "终末器官"。
IF 6.7 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.cardfail.2024.08.049
GERIN R. STEVENS MD, PhD , REBECCA COGSWELL MD
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引用次数: 0
Unlocking Diversity in Cardiovascular Clinical Research: Lessons from the Screening for Cardiac Amyloidosis With Nuclear Imaging in a Minority Populations Study 开启心血管临床研究的多样性:SCAN-MP (通过核成像筛查少数民族人群中的心脏淀粉样变性)研究的启示。
IF 6.7 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.cardfail.2024.04.019
Abdirahman Wardhere MD , Dimitrios Bampatsias MD , Elizabeth Cohn RN, PhD , Denise Fine RN, BSN , Cinthia de Freitas RN, BSN , Cesia Gallegos MD , Stephen Helmke RDCS, MPH , Natalia Ionescu PA , Janvier Ivrose PA , Carlos Rodriguez MD , Natalia Sabogal BS , Sergylensky Fils RN , Terrence Henry MD , Sergio Teruya MS , Ikram Ullah MD , Damian Kurian MD , Farbod Raiszadeh MD , Edward J. Miller MD , Frederick L. Ruberg MD , Mathew S. Maurer MD

Background

The Screening for Cardiac Amyloidosis with Nuclear Imaging in Minority Populations study seeks to determine the prevalence of transthyretin cardiac amyloidosis (ATTR-CA) among older Black or Caribbean Hispanic individuals with heart failure and an increased wall thickness. We noticed varied recruitment percentages across the recruiting sites and sought to determine the factors associated with greater percentage enrollment of eligible participants.

Methods

The percentage of enrolled to eligible participants was calculated across study sites. Baseline demographic and clinical characteristics, health literacy, trust in providers, perceived discrimination, area deprivation index (ADI) and English proficiency were compared by site using Kruskal-Wallis's test or one-way ANOVA for continuous variables and the Chi-Square test or Fisher's exact test for categorical variables. Wilcoxon rank sum and Chi-Square tests, with multiple comparisons correction using the false discovery rate (FDR) method, were used as post-hoc analysis when results were statistically significant.

Results

Among the four recruiting sites, Boston Medical Center, Columbia University Irving Medical Center, Harlem Hospital and Yale University, which employed different recruitment approaches, the percentage of participants enrolled among eligible participants differed, with the highest rate at Harlem Hospital (n=149 of 310, 48%), followed by Yale University (n=27 of 67, 40%), Boston University (n=247 of 655, 38%), and Columbia University (n=137of 442, 32%), p <0.01. Direct recruitment by the primary cardiovascular care team providing clinical care was associated with higher percent enrolled across sites as were higher education levels and English proficiency. Enrollment differences across sites were not associated with the number of chronic diseases, physician trust, perceived discrimination, or health literacy.

Conclusions

Recruitment of eligible under-represented minorities (URMs) in SCAN-MP was associated with approaches employed in recruitment, including direct initial contact by the primary cardiovascular care team providing the potential participant's clinical care. Such data may help improve approaches to more successful recruitment of URMs in clinical research.
研究背景通过核成像筛查少数民族人群中的心脏淀粉样变性研究旨在确定患有心力衰竭且心室壁厚度增加的老年黑人或加勒比海西班牙裔人中转铁蛋白心脏淀粉样变性(ATTR-CA)的患病率。我们注意到各招募点的招募比例各不相同,并试图确定与合格参与者招募比例较高有关的因素:方法:我们计算了各研究机构招募的合格参与者比例。对于连续变量,采用 Kruskal-Wallis 检验或单向方差分析;对于分类变量,采用 Chi-Square 检验或费雪精确检验。当结果具有统计学意义时,使用 Wilcoxon 秩和检验和 Chi-Square 检验进行事后分析,并使用错误发现率 (FDR) 方法进行多重比较校正:在波士顿医学中心、哥伦比亚大学欧文医学中心、哈莱姆医院和耶鲁大学这四个采用不同招募方法的招募地点中,符合条件的参与者的注册比例各不相同,其中哈莱姆医院的注册比例最高(310 人中有 149 人,占 48%),其次是耶鲁大学(67 人中有 27 人,占 40%)、波士顿大学(655 人中有 247 人,占 38%)和哥伦比亚大学(442 人中有 137 人,占 32%),P 结论:在 SCAN-MP 中招募符合条件的代表人数不足的少数族裔(URMs)与招募时采用的方法有关,包括提供潜在参与者临床护理的初级心血管护理团队的直接初步接触。这些数据可能有助于改进临床研究中更成功招募URM的方法。
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引用次数: 0
Drug Development in Hypertrophic Cardiomyopathy: Should Diastology Trump Functional Capacity Assessment? 肥厚型心肌病的药物开发:心肌病变应否压倒功能能力评估?
IF 6.7 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.cardfail.2024.04.022
MILIND Y. DESAI MD, MBA , CARLES DÍEZ-LÓPEZ MD
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引用次数: 0
Patient Focus: Moving Beyond Step Count: An Explanation of Real-World Walking Behaviors Are Associated With Early-Stage Heart Failure: A Project Baseline Health Study 关注患者:超越步数。解释现实世界中的步行行为与早期心力衰竭的关系:基线健康项目研究。
IF 6.7 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.cardfail.2024.04.002
SPENCER CARTER MD , JENNIFER T. THIBODEAU MD, MSCS
In this issue of the Journal of Cardiac Failure, Dr. Sooyoon Shin and colleagues look at whether information from wearable devices, or activity trackers, could improve how a medical team monitors activity limitations for people who are at risk of developing heart failure symptoms.
在本期《心力衰竭杂志》(Journal of Cardiac Failure)上,Sooyoon Shin 博士及其同事研究了来自可穿戴设备或活动追踪器的信息能否改善医疗团队对有可能出现心力衰竭症状的人的活动限制进行监控的方式。
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引用次数: 0
Filling the Void: How to Become a Palliative Cardiologist (and Why) 填补空白:如何(以及为何)成为一名姑息治疗心脏病专家。
IF 6.7 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.cardfail.2024.06.006
SARAH GODFREY MD, MPH , SARAH CHUZI MD, MSc , KATHARINE MANNING MD, MBE
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引用次数: 0
HFSA Scientific Statement: Update on Device Based Therapies in Heart Failure HFSA 科学声明:基于设备的心力衰竭治疗方法更新。
IF 6.7 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.cardfail.2024.07.007
JERRY D. ESTEP MD , HUSAM M. SALAH MD , SAMIR R. KAPADIA MD , DANIEL BURKHOFF MD, PhD , ANURADHA LALA MD , JAVED BUTLER MD, MPH, MBA , SHELLEY HALL MD , MARAT FUDIM MD, MHS
Heart failure (HF) is 1 of the major challenges of our time, given its increase in prevalence and related mortality rates. Foundational pharmacological therapies, including angiotensin receptor neprilysin inhibitors (ARNIs), beta-blockers, mineralocorticoid receptor antagonists (MRAs), and sodium-glucose co-transporter inhibitors (SGLTis), have been established for HF with reduced ejection fraction (HFrEF). Moreover, recent trials have established the role of SGLTis in patients with HF with preserved ejection fraction (HFpEF). However, even with these therapies, a substantial residual risk persists in both HFrEF and HFpEF. Alongside pharmacological advancements, device-based therapies have shown efficacy in HF management, including implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy (CRT). More recently, devices such as cardiac contractility modulation (CCM) and baroreflex activation therapy (BAT) have been approved by the FDA, although they lack comprehensive guideline recommendations. This scientific statement outlines the unmet needs in chronic HF, reviews contemporary data and provides a framework for integrating novel device-based therapies into current clinical workflows. It emphasizes the importance of early diagnosis and phenotyping, proper patient stratification and a personalized approach to combining pharmacological and device therapies. The document also highlights the need for further research into device interactions and patient selection to optimize outcomes, while recognizing the need for a more integrated approach to treatment so as to address the unmet needs and residual risks in HF management.
鉴于心力衰竭(HF)发病率和相关死亡率的上升,心力衰竭已成为当代的一大挑战。针对射血分数降低型心力衰竭(HFrEF)的基础药物疗法已经确立,包括血管紧张素受体肾素抑制剂(ARNIs)、β-受体阻滞剂、矿物质皮质激素受体拮抗剂(MRAs)和钠-葡萄糖协同转运体抑制剂(SGLTis)。此外,最近的试验还确定了 SGLTis 在射血分数保留型心房颤动(HFpEF)患者中的作用。然而,即使使用了这些疗法,HFrEF 和 HFpEF 患者仍然存在很大的残余风险。在药物治疗取得进展的同时,基于设备的疗法也显示出了治疗高血压的疗效,包括植入式心律转复除颤器(ICD)和心脏再同步化疗法(CRT)。最近,心脏收缩力调节 (CCM) 和巴反射激活疗法 (BAT) 等设备也获得了美国食品及药物管理局(FDA)的批准,但这些设备缺乏全面的指南建议。本科学报告概述了慢性高血压尚未满足的需求,回顾了当代数据,并提供了将基于新型设备的疗法纳入当前临床工作流程的框架。它强调了早期诊断和表型分析、适当的患者分层以及结合药物和器械疗法的个性化方法的重要性。该文件还强调了进一步研究器械相互作用和患者选择的必要性,以优化治疗效果,同时认识到需要采取更加综合的治疗方法,以解决高血压管理中尚未满足的需求和残余风险。
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引用次数: 0
Keeping Score of Heart Failure Guideline-directed Medical Therapy 心力衰竭指南指导下的药物治疗记分。
IF 6.7 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.cardfail.2024.09.006
ADAM D. DeVORE MD, MHS , GREGG C. FONAROW MD
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引用次数: 0
Contraception Counseling and Teratogenic Prescriptions Among Women With Systolic Heart Failure in a Safety-Net Health System 安全网医疗系统中收缩性心力衰竭妇女的避孕咨询和致畸处方。
IF 6.7 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.cardfail.2024.08.058
NIHARIKA NEELA MD , NICHOLAS S. HENDREN MD , SPENCER CARTER MD , LILIBETH HERNANDEZ PharmD , LAUREN K. TRUBY MD, MS , MARYJANE FARR MD , SANDEEP R. DAS MD
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引用次数: 0
Spotlight on Devices in Heart Failure 聚焦心力衰竭设备。
IF 6.7 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.cardfail.2024.10.434
Robert J. Mentz MD , Anuradha Lala MD
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引用次数: 0
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Journal of Cardiac Failure
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