Journal of Cardiac Failure最新文献

英文中文

The Advanced Heart Failure Workforce Crisis: A Path Forward 晚期心力衰竭劳动力危机：前进之路。

IF 8.2 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Cardiac Failure

Pub Date : 2026-02-01 DOI: 10.1016/j.cardfail.2025.10.018

MAYA GUGLIN M.D., Ph.D.

引用次数: 0

Letter to the Editor Reply: “The Advanced Heart Failure Workforce Crisis: A Path Forward” 致编辑的回信：“心力衰竭劳动力危机：前进之路”。

IF 8.2 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Cardiac Failure

Pub Date : 2026-02-01 DOI: 10.1016/j.cardfail.2025.11.472

EIRAN Z. GORODESKI MD, MPH , SHASHANK SHEKHAR MD , ROBERT A. MONTGOMERY MD

引用次数: 0

Have We Been Overlooking Lipoprotein(a) in Heart Failure? 我们是否忽视了心力衰竭中的脂蛋白(a) ？

IF 8.2 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Cardiac Failure

Pub Date : 2026-02-01 DOI: 10.1016/j.cardfail.2025.11.484

LAURA AGUILAR FRANCO MD, MPH , AMY L. ZHANG MD , A. RESHAD GARAN MD, MSc

引用次数: 0

Association between Baseline Hypertension and Longitudinal Functional Status in Obstructive Hypertrophic Cardiomyopathy Treated with Mavacamten. 马伐卡坦治疗梗阻性肥厚性心肌病患者基线高血压与纵向功能状态的关系

IF 8.2 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Cardiac Failure

Pub Date : 2026-02-01 DOI: 10.1016/j.cardfail.2025.12.010

Nosheen Reza, Nadim Mahmud, Melissa A Austin, Ellen Boakye, Estherland Duqueney, Parth Patel, Alejandro de Feria, Nicole Hornsby, Amy Marzolf, Anjali Tiku Owens

引用次数: 0

Lipoprotein(a) Levels and Adverse Outcomes in Heart Failure 心力衰竭患者脂蛋白(a)水平和不良结局。

IF 8.2 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Cardiac Failure

Pub Date : 2026-02-01 DOI: 10.1016/j.cardfail.2025.03.016

ADITHYA K. YADALAM MD, MSc , APOORVA GANGAVELLI MD, MSc , ALEXANDER C. RAZAVI MD, MPH, PhD , YI-AN KO PhD , AYMAN ALKHODER MD , NISREEN HAROUN MD , RAFIA LODHI MBBS , AHMED ELDAIDAMOUNI MBBCh , MAHMOUD AL KASEM MD , ARSHED A. QUYYUMI MD

Background

Although lipoprotein(a) [Lp(a)] level elevation is associated with new-onset heart failure (HF), it is unclear if elevated Lp(a) levels predict cardiovascular events in patients with chronic HF. Thus, we examined the association between Lp(a) levels and adverse cardiovascular outcomes in patients with HF.

Methods and Results

A total of 1088 patients with HF undergoing cardiac catheterization at Emory-affiliated hospitals from 2004 to 2022 were divided into low (<30 mg/dL), intermediate (30–49 mg/dL), and high (≥50 mg/dL) Lp(a) groups. The primary outcome was the composite of cardiovascular death and HF hospitalization. Outcomes were assessed by Lp(a) group with competing risk modeling accounting for noncardiovascular death after adjustment for demographics, traditional cardiovascular risk factors, ejection fraction, ischemic HF etiology, and N-terminal prohormone of brain natriuretic peptide. Sensitivity analyses were performed to explore for heterogeneity of effect. The median age was 67 years, 34% were women, 18% were Black, 74% had ischemic HF, and 60% had an ejection fraction of ≤40%. During a median follow-up time of 4.3 years, 474 composite events (44%) occurred. When compared with participants with Lp(a) <30 mg/dL after multivariable adjustment, those with Lp(a) 30-49 mg/dL (subdistribution hazard ratio [sHR] 1.35, 95% confidence interval 1.04–1.76, P = .025) and Lp(a) ≥50 mg/dL (sHR 1.38, 95% confidence interval 1.11–1.72, P = .004) had a significantly higher risk of cardiovascular death or HF hospitalization. This relationship seemed to diminish over time and was nominally stronger in those with ischemic versus nonischemic HF (P_interaction = .06), but did not meet significance after adjustment for multiple hypothesis testing.

Conclusions

In patients with HF, Lp(a) ≥30 mg/dL independently predicts the risk of cardiovascular death or HF hospitalization.

背景：虽然脂蛋白(a) [Lp(a)]水平升高与新发心力衰竭（HF）相关，但目前尚不清楚Lp(a)水平升高是否能预测慢性心力衰竭患者的心血管事件。因此，我们研究了心衰患者Lp(a)水平与不良心血管结局之间的关系。方法与结果：将2004 - 2022年在emory附属医院行心导管术的1088例HF患者分为低组(结论：在HF患者中，Lp(A)≥30 mg/dL独立预测心血管死亡或HF住院的风险。

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引用次数: 0

Health Literacy and Physical Function Among Older Black and Hispanic Individuals With Heart Failure 老年黑人和西班牙裔心力衰竭患者的健康素养和身体功能

IF 8.2 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Cardiac Failure

Pub Date : 2026-02-01 DOI: 10.1016/j.cardfail.2025.06.010

SHABATUN J. ISLAM MD , SERGIO TERUYA MD, MS , DENISE FINE BS , NATALIA SABOGAL BS , SERGYLENSKY FILS BS , IKRAM ULLAH MD , ANYA SANCHORAWALA BS , EDWARD MILLER MD , CESIA GALLEGOS MD , CINTHIA DE FREITAS RN , DAMIAN KURIAN MD , NATALIA IONESCU PA , IVROSE JANVIER PA , FARBOD RAISZADEH MD, PhD , EMELIA J. BENJAMIN MD, ScM , JARED W. MAGNANI MD, MSc , MATHEW S. MAURER MD , FREDERICK L. RUBERG MD

Background

Insufficient health literacy negatively impacts outcomes for heart failure (HF). Older adults with HF face significant barriers, including prevalence of multiple comorbidities, frailty and deficits in physical function, which can impact HF outcomes. Examination of the association between health literacy and physical function remains limited in older adults with HF. We investigated the cross-sectional associations of health literacy and physical function in a cohort of older self-identified Black and Hispanic patients with HF.

Methods and Results

The Screening for Cardiac Amyloidosis with Nuclear Imaging in Minority Populations (SCAN-MP) study recruited participants (age ≥ 60 years) of self-identified Black race or Hispanic ethnicity in New York City, Boston and New Haven. We measured health literacy by using the Newest Vital Sign, and we measured physical function by using the 6-minute walk duration (6MWD) and the Short Physical Performance Battery test (SPPB). Linear regression models evaluated the association between participants’ health-literacy levels and physical function, as defined by continuous measures of 6MWD and SPPB. Only 12.7% of the cohort (n = 433) had adequate health literacy. After adjusting for age, sex, number of comorbidities, and neighborhood social vulnerability, those with adequate (compared to limited) health literacy demonstrated better performance on the 6MWD (β = 37.5 m, 95% CI [1.49, 73.5]; P = 0.04) and SPPB (β = 1.18 (0.41, 1.95); P = 0.002).

Conclusion

Older Black or Hispanic participants with HF have an extremely high prevalence of limited health literacy, which is associated with poor physical function. Interventions targeting health literacy may represent an avenue to improve HF outcomes for patients with minoritized backgrounds.

背景：健康素养不足会对心力衰竭（HF）的预后产生负面影响。老年HF患者面临重大障碍，包括多种合并症的流行、虚弱和身体功能缺陷，这些都可能影响HF的结局。对老年心衰患者健康素养与身体功能之间关系的研究仍然有限。我们调查了一组自认为是黑人和西班牙裔的老年心衰患者的健康素养和身体功能的横断面关联。方法与结果：在少数人群中使用核成像筛查心脏淀粉样变性（SCAN-MP）研究在纽约市、波士顿和纽黑文招募了自认为是黑人或西班牙裔的参与者（年龄0 - 60岁）。我们使用最新生命体征测量健康素养，使用6分钟步行时间（6MWD）和短物理性能电池测试（SPPB）测量身体功能。线性回归模型通过连续测量6MWD和SPPB来评估参与者的健康素养水平与身体功能之间的关系。只有12.7%的队列（n=433）有足够的健康素养。在调整了年龄、性别、合共病数量和社区社会脆弱性后，健康素养较好的人群在6MWD （β=37.5 m, 95% CI [1.49, 73.5], p=0.04）和SPPB （β=1.18 (0.41, 1.95), p=0.002）上表现更好。结论：老年黑人或西班牙裔HF患者健康素养有限的患病率极高，这与身体功能差有关。针对健康素养的干预措施可能是改善少数族裔心衰患者预后的一种途径。

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引用次数: 0

Heart Month and Her Heart Health Reimagined 心脏月和她的心脏健康重新想象

IF 8.2 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Cardiac Failure

Pub Date : 2026-02-01 DOI: 10.1016/j.cardfail.2026.01.004

Anuradha Lala MD , Martha Gulati MD MS , Robert J. Mentz MD

引用次数: 0

Incentivizing a Safety Net Cardiac Recovery Pathway via the Heart Transplant Allocation System. 通过心脏移植分配系统激励安全网心脏恢复途径。

IF 8.2 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Cardiac Failure

Pub Date : 2026-01-31 DOI: 10.1016/j.cardfail.2026.01.009

Snehal R Patel, Josef Stehlik, Shelley Hall, Jennifer Cowger, Stavros G Drakos

引用次数: 0

Hidden Structure of Care Coordination in Heart Failure Care Transitions: A Mixed-method Network Analysis of Clinical Notes. 心衰护理过渡中护理协调的隐藏结构：临床记录的混合方法网络分析。

IF 8.2 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Cardiac Failure

Pub Date : 2026-01-31 DOI: 10.1016/j.cardfail.2025.12.008

Sijia Wei, Eleanor S McConnell, Kirsten N Corazzini, James Moody, Wei Pan, Jeffrey A Linder, Bradi B Granger

Introduction: Patients with heart failure, especially those with lower socioeconomic position, are vulnerable to adverse outcomes of care fragmentation. Care coordination mitigates care fragmentation, but a comprehensive assessment of relationships among all relevant clinicians that enable it is lacking. This explanatory sequential mixed-methods study explores how patients' clinician network characteristics relate to their social context and clinical outcomes following heart failure care transitions.

Methods: We conducted a bipartite social network analysis to describe clinician networks for 1,269 patients first hospitalized with heart failure in a southeastern U.S. health system. Networks were constructed using electronic health record notes one year before, during, and one year after the index hospitalization (January 2015- February 2020). We then used stratified purposive sampling to select 11 adults with diverse socio-economic positions but similar illness severity and comorbidity. For these patients, we conducted qualitative chart reviews of clinical notes. Each patient's clinician network size, density, and centrality were integrated with qualitative findings to explore clinician networks' relationship to patients' social context and outcomes.

Results: Patients with higher socio-economic positions used fewer acute care services and lived longer; their clinicians, particularly outpatient clinicians, tended to have denser and more centrally located team networks before the index hospitalization that persisted after the index hospitalization; their telephone notes indicated more regular and reciprocal communication patterns between patients and clinicians.

Conclusions: Early involvement and better communication among clinician networks with greater density and centrality may help to explain better care transition outcomes observed among patients with higher socio-economic positions.

心衰患者，特别是那些社会经济地位较低的患者，容易受到护理碎片化的不良后果的影响。护理协调减轻了护理碎片化，但缺乏对所有相关临床医生之间关系的全面评估。本解释性顺序混合方法研究探讨患者临床医生网络特征如何与他们的社会背景和心力衰竭护理转变后的临床结果相关。方法：我们进行了一个双部社会网络分析来描述美国东南部卫生系统中1269例首次住院的心力衰竭患者的临床医生网络。使用电子健康记录在索引住院前、住院期间和住院后一年（2015年1月至2020年2月）构建网络。然后，我们采用分层有目的抽样的方法选择了11名不同社会经济地位但疾病严重程度和合并症相似的成年人。对于这些患者，我们对临床记录进行了定性图表回顾。每个患者的临床医生网络的规模、密度和中心性与定性研究结果相结合，以探索临床医生网络与患者社会环境和结果的关系。结果：社会经济地位越高的患者使用急症护理服务越少，寿命越长；他们的临床医生，特别是门诊临床医生，在指标住院前往往有更密集和更集中的团队网络，在指标住院后持续存在；他们的电话记录表明，患者和临床医生之间的交流模式更加规律和互惠。结论：在密度和中心性较高的临床医生网络中，早期参与和更好的沟通可能有助于解释在社会经济地位较高的患者中观察到的更好的护理过渡结果。

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引用次数: 0

"Readiness for Discharge" as a Novel Endpoint in Heart Failure Trials. “出院准备”作为心力衰竭试验的新终点。

IF 8.2 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Cardiac Failure

Pub Date : 2026-01-24 DOI: 10.1016/j.cardfail.2026.01.008

Muhammad Shahzeb Khan, Ahmed Mustafa Rashid, Sean P Collins, Mark C Petrie, Jeffrey Testani, Javed Butler

引用次数: 0

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