An ethno-botanical study carried out in the village area near to Bondla wildlife sanctuary of Bondla, Goa revealed therapeutic application of 15 plant species representing 14 families. These plants are use for a wide range of common health ailments like Infertility, Hair loss, Cervical adenitis, Cancer, burnt wound, Antidote for opium, Diabetes, Kidney stone, Piles, Cough, Worm infestation, Constipation, Bronchial asthma, Sprain, Fracture, Leucorrhoea and Wound healing etc. Majorities of preparation are taken orally and local applications in form of decoction and paste. Information of medicinal claim was collected from elderly people and local healers residing in the vicinity of Bondla wild life sanctuary. The study describes the details of Botanical identity, Family, Local Konkani name, Sanskrit name, English name, Parts of the plant used, therapeutic uses, Process of preparation, Dosage, mode and route of application.
{"title":"Ethno-medico-botanical claims of Bondla wildlife sanctuary vicinity of Goa","authors":"Das Sangram Keshari, Mohanty Bishnupriya","doi":"10.31254/jahm.2022.8105","DOIUrl":"https://doi.org/10.31254/jahm.2022.8105","url":null,"abstract":"An ethno-botanical study carried out in the village area near to Bondla wildlife sanctuary of Bondla, Goa revealed therapeutic application of 15 plant species representing 14 families. These plants are use for a wide range of common health ailments like Infertility, Hair loss, Cervical adenitis, Cancer, burnt wound, Antidote for opium, Diabetes, Kidney stone, Piles, Cough, Worm infestation, Constipation, Bronchial asthma, Sprain, Fracture, Leucorrhoea and Wound healing etc. Majorities of preparation are taken orally and local applications in form of decoction and paste. Information of medicinal claim was collected from elderly people and local healers residing in the vicinity of Bondla wild life sanctuary. The study describes the details of Botanical identity, Family, Local Konkani name, Sanskrit name, English name, Parts of the plant used, therapeutic uses, Process of preparation, Dosage, mode and route of application.","PeriodicalId":15252,"journal":{"name":"Journal of Ayurvedic and Herbal Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86504854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Joshi, R. Yadav, S. Shrestha, Jitendra Shrestha
Background: Hypothyroidism is one of the major endrocrine disorders seen in general population worldwide. Although modern drugs are quite effective in managing hypothyroidism, it is subject to sustaining certain side effects. So, we aim to evaluate the efficacy of Ayurvedic herbal formulation and Ayurvedic herbo-mineral formulation in managing hypothyroidism in Nepalese population. Methods and analysis: This study was a randomized, double-blind, and controlled trial. A total of 50 participants with the diagnosis of hypothyroidism was randomly assigned to the intervention group or control group in a ratio of 1:1 for 4 weeks. The primary outcome measure was the thyroidstimulating hormone level, and secondary outcome measures was the change in body mass index, waist-hip ratio, blood glucose level, lipid profile, liver function tests and renal function tests between the baseline and at 4 weeks after intervention. Statistical analysis was done by comparing categorical variables using chi-square test and Fisher’s exact test and comparing continuous variables using paired and unpaired student’s t test. Results: There was a decrease in TSH levels of the participants by 12.5% and 7.9%, after intervention with AHF and AHMF, respectively. There were a small statistical significant difference only in waist-hip ratio ( p= 0.04) when compared before and after treatment with AHF and AHMF whereas there was no significant changes observed in other clinical variables after intervention with AHF and AHMF. Conclusion: This study may provide new evidence for the effectiveness of Ayurvedic herbal formulation and Ayurvedic herbo-mineral formulation in hypothyroidism in context of Nepal.
{"title":"Efficacy of Ayurvedic herbal formulation and Ayurvedic herbo-mineral formulation in hypothyroidism patients","authors":"A. Joshi, R. Yadav, S. Shrestha, Jitendra Shrestha","doi":"10.31254/jahm.2021.7405","DOIUrl":"https://doi.org/10.31254/jahm.2021.7405","url":null,"abstract":"Background: Hypothyroidism is one of the major endrocrine disorders seen in general population worldwide. Although modern drugs are quite effective in managing hypothyroidism, it is subject to sustaining certain side effects. So, we aim to evaluate the efficacy of Ayurvedic herbal formulation and Ayurvedic herbo-mineral formulation in managing hypothyroidism in Nepalese population. Methods and analysis: This study was a randomized, double-blind, and controlled trial. A total of 50 participants with the diagnosis of hypothyroidism was randomly assigned to the intervention group or control group in a ratio of 1:1 for 4 weeks. The primary outcome measure was the thyroidstimulating hormone level, and secondary outcome measures was the change in body mass index, waist-hip ratio, blood glucose level, lipid profile, liver function tests and renal function tests between the baseline and at 4 weeks after intervention. Statistical analysis was done by comparing categorical variables using chi-square test and Fisher’s exact test and comparing continuous variables using paired and unpaired student’s t test. Results: There was a decrease in TSH levels of the participants by 12.5% and 7.9%, after intervention with AHF and AHMF, respectively. There were a small statistical significant difference only in waist-hip ratio ( p= 0.04) when compared before and after treatment with AHF and AHMF whereas there was no significant changes observed in other clinical variables after intervention with AHF and AHMF. Conclusion: This study may provide new evidence for the effectiveness of Ayurvedic herbal formulation and Ayurvedic herbo-mineral formulation in hypothyroidism in context of Nepal.","PeriodicalId":15252,"journal":{"name":"Journal of Ayurvedic and Herbal Medicine","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84460928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: With an incidence of 3%-5% in the general population and up to 20% in people with diabetes, peak incidence of frozen shoulder is more common in women and in manual workers between the age of 40 and 60yrs. Though multiple interventions have been studied on the frozen shoulder, the complete and the effective treatment is indefinite. Nasya karma is one among the panchakarma therapies of Ayurvedic system of medicine which can deliver the potential effects to the patients of frozen shoulder or apabahuka. Purpose: The objective of this study was to review the case reports and case series that are published on nasya karma and apabahuka or frozen shoulder. Design: Systematic review. Methods: PubMed/MEDLINE, Cochrane (CENTRAL), EMBASE, Google Scholar, TKDL, AYUSH and DHARA databases were screened from inception until March 8th, 2020. References of the full text articles were screened and selected articles by searching manually as a next step. Based on the pre-specified inclusion criteria articles were screened and finally 5 case reports and 0 case series were included for the study. Results: All the 5 studies included in the review administered nasya karma to the patients suffering from apabahuka or frozen shoulder and assessed pain, severity of the pain, VAS (visual analogue scale), stiffness, ROM (Range of movements) like flexion, extension, abduction, adduction, internal rotation and external rotation, forward elevation, lateral elevation, restricted movements and constant assessment scale of shoulder joint before and after the treatment which showed significant improvement in all the parameters. Conclusions: Nasya karma, one of the panchakarma therapies in Ayurvedic system of medicine constitutes the prime modality of treatment in the management of jatru-urdhwagata rogas mainly apabahuka or the frozen shoulder. Though present review showed significant changes in all the parameters, there are several limitations besides the quality of reporting, that is generally low in the included case reports. In addition, this review provides a comprehensive knowledge that may assist the researcher as a supplementary by giving an intuition for the execution of RCT’s and clinical studies further on the domain studied. Having negligible number of systematic reviews in Ayurveda and absence of systematic reviews on case studies or reports and series, this review may serve as a preliminary step towards conducting more systematic reviews in Ayurvedic system of medicine which is the need of hour..
{"title":"Role of Nasya Karma (nasal instillation therapy) in Apabahuka (frozen shoulder)– A qualitative systematic review","authors":"Yogitha Bali M.R, J. Ebnezar","doi":"10.31254/jahm.2021.7412","DOIUrl":"https://doi.org/10.31254/jahm.2021.7412","url":null,"abstract":"Background: With an incidence of 3%-5% in the general population and up to 20% in people with diabetes, peak incidence of frozen shoulder is more common in women and in manual workers between the age of 40 and 60yrs. Though multiple interventions have been studied on the frozen shoulder, the complete and the effective treatment is indefinite. Nasya karma is one among the panchakarma therapies of Ayurvedic system of medicine which can deliver the potential effects to the patients of frozen shoulder or apabahuka. Purpose: The objective of this study was to review the case reports and case series that are published on nasya karma and apabahuka or frozen shoulder. Design: Systematic review. Methods: PubMed/MEDLINE, Cochrane (CENTRAL), EMBASE, Google Scholar, TKDL, AYUSH and DHARA databases were screened from inception until March 8th, 2020. References of the full text articles were screened and selected articles by searching manually as a next step. Based on the pre-specified inclusion criteria articles were screened and finally 5 case reports and 0 case series were included for the study. Results: All the 5 studies included in the review administered nasya karma to the patients suffering from apabahuka or frozen shoulder and assessed pain, severity of the pain, VAS (visual analogue scale), stiffness, ROM (Range of movements) like flexion, extension, abduction, adduction, internal rotation and external rotation, forward elevation, lateral elevation, restricted movements and constant assessment scale of shoulder joint before and after the treatment which showed significant improvement in all the parameters. Conclusions: Nasya karma, one of the panchakarma therapies in Ayurvedic system of medicine constitutes the prime modality of treatment in the management of jatru-urdhwagata rogas mainly apabahuka or the frozen shoulder. Though present review showed significant changes in all the parameters, there are several limitations besides the quality of reporting, that is generally low in the included case reports. In addition, this review provides a comprehensive knowledge that may assist the researcher as a supplementary by giving an intuition for the execution of RCT’s and clinical studies further on the domain studied. Having negligible number of systematic reviews in Ayurveda and absence of systematic reviews on case studies or reports and series, this review may serve as a preliminary step towards conducting more systematic reviews in Ayurvedic system of medicine which is the need of hour..","PeriodicalId":15252,"journal":{"name":"Journal of Ayurvedic and Herbal Medicine","volume":"300 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82640934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Psoriasis is one among the most common skin disorders encountered in clinical practice. It is a chronic disease that has substantial psychological and social impact on a patient’s life. A Case of psoriasis was managed with Vaman (Shodhan and Shaman) chikitsa explained in samhitas. Case: A 22 years old female patient presented with complaints erythematous patches, severe itching, and burning sensation dry and scaly patch since 1 year. Management: Pachan was done with Trikatu churna. Internal oleation with Mahapanchtikta ghrita in arohana krama (increasing dose). External oleation was done with Nimba Taila and Mnjisthadi Kwath sarvang vashpa svedana. For Vaman Akanthpana Godugdha was given. Vaman dravya was Madanphala Churna 2gm, Yashtimadhu Churna 2gm, Vacha Churna 1 gm, Saindhav 2gm, Madhu for paste. Yashtimadhu Kwath was given as vamnopag dravya.
{"title":"Effect of vaman on psoriasis (Ekakushta): A case study","authors":"Richa Acharya","doi":"10.31254/jahm.2021.7402","DOIUrl":"https://doi.org/10.31254/jahm.2021.7402","url":null,"abstract":"Psoriasis is one among the most common skin disorders encountered in clinical practice. It is a chronic disease that has substantial psychological and social impact on a patient’s life. A Case of psoriasis was managed with Vaman (Shodhan and Shaman) chikitsa explained in samhitas. Case: A 22 years old female patient presented with complaints erythematous patches, severe itching, and burning sensation dry and scaly patch since 1 year. Management: Pachan was done with Trikatu churna. Internal oleation with Mahapanchtikta ghrita in arohana krama (increasing dose). External oleation was done with Nimba Taila and Mnjisthadi Kwath sarvang vashpa svedana. For Vaman Akanthpana Godugdha was given. Vaman dravya was Madanphala Churna 2gm, Yashtimadhu Churna 2gm, Vacha Churna 1 gm, Saindhav 2gm, Madhu for paste. Yashtimadhu Kwath was given as vamnopag dravya.","PeriodicalId":15252,"journal":{"name":"Journal of Ayurvedic and Herbal Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89675375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Mineral dosage forms (Rasoushadhis) with minute dose and quick activity has more bio-availability. Various single bhasmas or formulations are indicated in various disorders. Pandu is one among the rasa pradoshaja vikara. As the causes severalises the treatment modality also varies. Iron supplement alone is not sufficient to treat pandu roga, there are many other factors which influences in the treatment of pandu. Method: After the review of Rasaratnasamucchaya (RRS) the drugs like Shilajatu (Asphaltum punjabinum), Tamra (Cuprum), Loha (Ferrum), Mandura (Iron oxide), Yashada (Zinc) is also useful in the treatment of pandu roga. Along with this, the formulations indicated in Pandu roga mentioned in RRS contains other ingredients like abhraka, Swarna, rajata, rasa sindura, haratala, manashila, vaikranta, Swarna makshika, kansya with other herbal drugs may have synergetic activity. The present study was undertaken to review the single Bhasma indicated in Pandu as per the textbook of Rasaratnasamucchaya. Result: So in general, mandura bhasma is more effective in children comparing to lohabhasma, both acts as a hepatoprotective and improves the level of haemoglobin. Shilajatu acts a chelator when combined with the lohabhasma, tamrabhasma helps in the absorption of iron in the form of ferritin. Zinc is known to improve enzymatic action and thus helps in the better absorption of iron.
{"title":"An approach to Panduhara Rasa Dravyas as per Rasa Ratna Samucchaya- A review","authors":"Akshatha, Seema Mandi Balanaga Reddy, Surekha Shankrappa Madikeri","doi":"10.31254/jahm.2021.7409","DOIUrl":"https://doi.org/10.31254/jahm.2021.7409","url":null,"abstract":"Background: Mineral dosage forms (Rasoushadhis) with minute dose and quick activity has more bio-availability. Various single bhasmas or formulations are indicated in various disorders. Pandu is one among the rasa pradoshaja vikara. As the causes severalises the treatment modality also varies. Iron supplement alone is not sufficient to treat pandu roga, there are many other factors which influences in the treatment of pandu. Method: After the review of Rasaratnasamucchaya (RRS) the drugs like Shilajatu (Asphaltum punjabinum), Tamra (Cuprum), Loha (Ferrum), Mandura (Iron oxide), Yashada (Zinc) is also useful in the treatment of pandu roga. Along with this, the formulations indicated in Pandu roga mentioned in RRS contains other ingredients like abhraka, Swarna, rajata, rasa sindura, haratala, manashila, vaikranta, Swarna makshika, kansya with other herbal drugs may have synergetic activity. The present study was undertaken to review the single Bhasma indicated in Pandu as per the textbook of Rasaratnasamucchaya. Result: So in general, mandura bhasma is more effective in children comparing to lohabhasma, both acts as a hepatoprotective and improves the level of haemoglobin. Shilajatu acts a chelator when combined with the lohabhasma, tamrabhasma helps in the absorption of iron in the form of ferritin. Zinc is known to improve enzymatic action and thus helps in the better absorption of iron.","PeriodicalId":15252,"journal":{"name":"Journal of Ayurvedic and Herbal Medicine","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76461760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The plant Andrographis echioidesis play a vital role in curing various human diseases. According to traditional siddha medicinal system till date it is accountable as to cure 81 diseases. The cost of fresh leaves is Rs 1750/Kg in Medicinal live, a largest online medicinal supplier in India. This much of cost may be due to its demand in siddha medicine to prepare various medicine is so high. Even though, this much of demand is exists but no any scientific validation and documentation for this plant possessing phytocompounds to cure the disease. Hence the present study was aimed to evaluate the possible bioactive functional group present in the methanol leaf extract of Andrographis echioides. The major functional group present in this plant was determined by FTIR analysis showed the existence of functional groups such as alkanes, aromatic compound, conjugated alkene, cyclic alkene, nitro compound, aromatics, carboxylic acid, phenol, aromatics ester, alkyl aryl ether, vinyl ether, ester, tertiary alcohol, primary alcohol, alkyl halides, alkene and halo compounds.
{"title":"Phytochemical screening by FTIR spectroscopic analysis of methanol leaf extract of herb Andrographis echioides","authors":"K. Rani, M. Mumtaz, R. Priyank, M. Chandran","doi":"10.31254/jahm.2021.7408","DOIUrl":"https://doi.org/10.31254/jahm.2021.7408","url":null,"abstract":"The plant Andrographis echioidesis play a vital role in curing various human diseases. According to traditional siddha medicinal system till date it is accountable as to cure 81 diseases. The cost of fresh leaves is Rs 1750/Kg in Medicinal live, a largest online medicinal supplier in India. This much of cost may be due to its demand in siddha medicine to prepare various medicine is so high. Even though, this much of demand is exists but no any scientific validation and documentation for this plant possessing phytocompounds to cure the disease. Hence the present study was aimed to evaluate the possible bioactive functional group present in the methanol leaf extract of Andrographis echioides. The major functional group present in this plant was determined by FTIR analysis showed the existence of functional groups such as alkanes, aromatic compound, conjugated alkene, cyclic alkene, nitro compound, aromatics, carboxylic acid, phenol, aromatics ester, alkyl aryl ether, vinyl ether, ester, tertiary alcohol, primary alcohol, alkyl halides, alkene and halo compounds.","PeriodicalId":15252,"journal":{"name":"Journal of Ayurvedic and Herbal Medicine","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78924032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helminthiasis is a major health issue worldwide. Over 200 million peoples and 600 million school age children are manifested by these parasites. It is a wide spread neglected tropical decease of developing countries and affect majorly poor peoples. The helminthic parasites weaken the immune system and increase susceptibility to HIV/AIDS, pneumonia, tuberculosis, malaria. Trematode (flukes), cestode (tapeworm) and nematodes (round worm) are the members of helminth infection. Ascaris lumbricoides, Nector americanus, Ancyclostoma duodenale and Trichuris trichuria are are the parasites which spread infection without any vector and cause serious complications in lungs and CNS. Schistosoma species (trematodes or flukes) are mainly transmitted by contaminated fresh water. Cestodes (Taenia solium, Taenia saginata) transmit infection through contaminated and uncooked red meat and cyst in different tissue. Cyst in CNS results in pathological changes called neurocysticercosis. Nature is a big store house of remedies for ailments of mankind. Due to toxic effects of synthetic drugs, there’s a great need to invent new bio-active constituents and plants can complete this need effectually.
{"title":"Anthelmintic lead compounds and their targets for drug development","authors":"S. Singla, S. Kaur","doi":"10.31254/jahm.2021.7410","DOIUrl":"https://doi.org/10.31254/jahm.2021.7410","url":null,"abstract":"Helminthiasis is a major health issue worldwide. Over 200 million peoples and 600 million school age children are manifested by these parasites. It is a wide spread neglected tropical decease of developing countries and affect majorly poor peoples. The helminthic parasites weaken the immune system and increase susceptibility to HIV/AIDS, pneumonia, tuberculosis, malaria. Trematode (flukes), cestode (tapeworm) and nematodes (round worm) are the members of helminth infection. Ascaris lumbricoides, Nector americanus, Ancyclostoma duodenale and Trichuris trichuria are are the parasites which spread infection without any vector and cause serious complications in lungs and CNS. Schistosoma species (trematodes or flukes) are mainly transmitted by contaminated fresh water. Cestodes (Taenia solium, Taenia saginata) transmit infection through contaminated and uncooked red meat and cyst in different tissue. Cyst in CNS results in pathological changes called neurocysticercosis. Nature is a big store house of remedies for ailments of mankind. Due to toxic effects of synthetic drugs, there’s a great need to invent new bio-active constituents and plants can complete this need effectually.","PeriodicalId":15252,"journal":{"name":"Journal of Ayurvedic and Herbal Medicine","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73584628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ostraceous psoriasis, extremely rear forms of psoriasis is manifested as typical lesion on the skin of the patient resembling an oyster shell. Psoriatic patients are commonly using alternative and complementary medicine due to limited efficacy of allopathic medicine. Herein, we report a 21 year old male patient with Ostraceous psoriasis who was successfully treated with Unani oral and topical formulations. During 90 days of treatment with Unani drugs, there was substantial improvement in subjective and objective parameters with no adverse effect.
{"title":"An effective treatment of ostraceous psoriasis by Unani medicine- A case report from Kashmir North India","authors":"Tariq Rahi, Naquibul Islam, T. Rafeeqi","doi":"10.31254/jahm.2021.7403","DOIUrl":"https://doi.org/10.31254/jahm.2021.7403","url":null,"abstract":"Ostraceous psoriasis, extremely rear forms of psoriasis is manifested as typical lesion on the skin of the patient resembling an oyster shell. Psoriatic patients are commonly using alternative and complementary medicine due to limited efficacy of allopathic medicine. Herein, we report a 21 year old male patient with Ostraceous psoriasis who was successfully treated with Unani oral and topical formulations. During 90 days of treatment with Unani drugs, there was substantial improvement in subjective and objective parameters with no adverse effect.","PeriodicalId":15252,"journal":{"name":"Journal of Ayurvedic and Herbal Medicine","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84444430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Nataraj, R. Suresh, Chennaveerappa, P. Rao, S. Shetty, S. Gopkrishna, S. Ambika, Padmanabha Lal
Background: COVID-19 has emerged as the latest pandemic that erupted in the Wuhan City of People’s Republic of China in December 2019, which is affecting human health and economy across the world. The ongoing COVID-19 outbreak in developed countries also highlights the fact that developed countries and rich populations are not immune to infectious disease outbreaks. Coronaviruses (CoVs) are enveloped, single-stranded, positive-sense RNA viruses that belong to the Coronaviridae family. SARS-CoV-2 is a member of the beta CoV genus, which also includes SARS-CoV-1 and MERS-CoV. The lack of approved effective drug therapeutic protocols for CoVs would make treating newly emerged COVID-19 infections globally difficult. Objective: A clinical study was conducted to evaluate the safety and efficacy of AYUSH 64 a poly herbal drug as an adjunct therapy to standard of care in mild to moderate Covid 19 patients Materials and methods: A prospective, open-label, randomized, parallel assignment, single-center clinical study with pre-test and post-test design was conducted at Covid hospital, Hassan institute of medical sciences between September 2020 to December 2020. A total 60 diagnosed cases (22-75 years of age) of Covid 19 were randomly allocated to both the groups. Control group received standard of care (SOC) as prescribed by the ICMR/WHO and state government, Trial Group received one week intervention of AYUSH 64 tablets at the dose of 2gm/day along with standard of care. Assessment of parameters viz. improvement in the symptoms, hematology, liver function, kidney function tests, acute phase reactants, Serum ferritin, Di dimer, LDH, and hsCRP were analyzed on day zero, day three and day seven. Results: One-week intervention of AYUSH-64 along with SOC helped to recover from Covid 19 symptoms. The intervention was safe on blood and biochemical parameters. Trial group has shown significant reduction in acute phase reactants viz hsCRP, LDH, Di dimer and Ferritin compare to the control group. No serious drug adverse effects were observed during the study. Conclusion: AYUSH-64 along-with standard care in mild to moderate covid 19 patients is safe and efficacious and this may be used as add-on to standard care for early recovery and better outcome.
{"title":"Safety and efficacy of Ayush 64 tablets as an adjunct therapy and its effect on bio- markers in mild to moderate covid-19 patients","authors":"H. Nataraj, R. Suresh, Chennaveerappa, P. Rao, S. Shetty, S. Gopkrishna, S. Ambika, Padmanabha Lal","doi":"10.31254/jahm.2021.7407","DOIUrl":"https://doi.org/10.31254/jahm.2021.7407","url":null,"abstract":"Background: COVID-19 has emerged as the latest pandemic that erupted in the Wuhan City of People’s Republic of China in December 2019, which is affecting human health and economy across the world. The ongoing COVID-19 outbreak in developed countries also highlights the fact that developed countries and rich populations are not immune to infectious disease outbreaks. Coronaviruses (CoVs) are enveloped, single-stranded, positive-sense RNA viruses that belong to the Coronaviridae family. SARS-CoV-2 is a member of the beta CoV genus, which also includes SARS-CoV-1 and MERS-CoV. The lack of approved effective drug therapeutic protocols for CoVs would make treating newly emerged COVID-19 infections globally difficult. Objective: A clinical study was conducted to evaluate the safety and efficacy of AYUSH 64 a poly herbal drug as an adjunct therapy to standard of care in mild to moderate Covid 19 patients Materials and methods: A prospective, open-label, randomized, parallel assignment, single-center clinical study with pre-test and post-test design was conducted at Covid hospital, Hassan institute of medical sciences between September 2020 to December 2020. A total 60 diagnosed cases (22-75 years of age) of Covid 19 were randomly allocated to both the groups. Control group received standard of care (SOC) as prescribed by the ICMR/WHO and state government, Trial Group received one week intervention of AYUSH 64 tablets at the dose of 2gm/day along with standard of care. Assessment of parameters viz. improvement in the symptoms, hematology, liver function, kidney function tests, acute phase reactants, Serum ferritin, Di dimer, LDH, and hsCRP were analyzed on day zero, day three and day seven. Results: One-week intervention of AYUSH-64 along with SOC helped to recover from Covid 19 symptoms. The intervention was safe on blood and biochemical parameters. Trial group has shown significant reduction in acute phase reactants viz hsCRP, LDH, Di dimer and Ferritin compare to the control group. No serious drug adverse effects were observed during the study. Conclusion: AYUSH-64 along-with standard care in mild to moderate covid 19 patients is safe and efficacious and this may be used as add-on to standard care for early recovery and better outcome.","PeriodicalId":15252,"journal":{"name":"Journal of Ayurvedic and Herbal Medicine","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91532719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Based on our knowledge and actual survey results in control and experiment of treament therapy of oral ulcer disease causing by toxic heat, which is one of the most popular oral ulcer diseases, by complementary/alternative medicine and especially the consumption of herbs. we briefly dialectic and recommend on treatment stratergy of this disease by suggested herbal medicine prescription. This work may be helpful to give insight knowledge of the oral ulcer treatment to practitioners, consumers and clinicians.
{"title":"The effective treatment therapy of oral ulcers by traditional medicine: A prospective science opinion","authors":"Thi-Ngoc Lanh, Quang-Ung Le, Horng-Liang Lay","doi":"10.31254/jahm.2021.7401","DOIUrl":"https://doi.org/10.31254/jahm.2021.7401","url":null,"abstract":"Based on our knowledge and actual survey results in control and experiment of treament therapy of oral ulcer disease causing by toxic heat, which is one of the most popular oral ulcer diseases, by complementary/alternative medicine and especially the consumption of herbs. we briefly dialectic and recommend on treatment stratergy of this disease by suggested herbal medicine prescription. This work may be helpful to give insight knowledge of the oral ulcer treatment to practitioners, consumers and clinicians.","PeriodicalId":15252,"journal":{"name":"Journal of Ayurvedic and Herbal Medicine","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74808954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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