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Sthoulya Asthadosha- Review on understanding of complications of obesity through Ayurveda and modern science 通过阿育吠陀和现代科学对肥胖并发症的认识综述
Pub Date : 2021-12-30 DOI: 10.31254/jahm.2021.7411
Sidram Guled, Jyoti
Sthoulya is major problem the whole world is facing today. Recently many research works have suggested that, over 1.9 billion population of middle age are overweight and 650 million are suffering with obesity worldwide. In India, over 135 million people had suffered obesity. It is a major reason of medical and financial burdens for the government. Central obesity is one among the important risk for vascular diseases of heart (CVDs) and a major reason of mortality in India. Atisthula who is having excessive deposition of meda and mamsa in sthana, udara and sphik is considered as dosha (that can cause many untoward health consequences) as per Ayurveda. Modern pathophysiology also suggests central obesity which is considered Metabolically unhealthy obesity (MUHO) in contrast with peripheral obesity as metabolically healthy obesity (MHO). Charaka said eight doshas (complications or syndrome) namely Ayukshaya (reduced life expectancy), Javoparodha (reduced physical activities), Krichravyavayata (infertility both male and female, loss of libido and erectile dysfunction), Dourbalya (reduced physical strength and reduced immunity), Dourgandya (Bromhidrosis), Swedabhada (difficulties with sweating), Atikshudha (increased appetite and hunger) and Atitrishna (excessive thirst). Asthadosha when analysed critically covers almost complications and consequences of obesity explained in modern literature. After reviewing both Ayurveda and modern literature about the obesity and its complications there are lots of similarities are observed and makes easy to understand sthoulya better.
Sthoulya是当今世界面临的主要问题。最近许多研究表明,全球有超过19亿的中年人超重,6.5亿人患有肥胖症。在印度,超过1.35亿人患有肥胖症。这是政府医疗和财政负担的主要原因。中心性肥胖是发生心血管疾病的重要风险之一,也是印度人死亡的主要原因之一。根据阿育吠陀的说法,在sthana, udara和sphik中有过多的meda和mamsa沉积的Atisthula被认为是dosha(会导致许多不利的健康后果)。现代病理生理学也表明,中心性肥胖被认为是代谢不健康肥胖(MUHO),而周围性肥胖被认为是代谢健康肥胖(MHO)。查拉卡说了八个dosha(并发症或综合征),即Ayukshaya(预期寿命缩短)、Javoparodha(体力活动减少)、Krichravyavayata(男性和女性不孕、性欲减退和勃起功能障碍)、Dourbalya(体力下降和免疫力下降)、Dourgandya(腋臭)、Swedabhada(出汗困难)、Atikshudha(食欲增加和饥饿)和Atitrishna(过度口渴)。当对肥胖进行批判性分析时,它几乎涵盖了现代文献中所解释的肥胖并发症和后果。在回顾了阿育吠陀和现代关于肥胖及其并发症的文献后,我们发现了许多相似之处,这有助于更好地理解舒利亚。
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引用次数: 0
Basti Therapy (medicated enema) in gynecological practice: A way forward in managing oligo-hypomenorrhoea (Artavakshaya) Basti疗法(药物灌肠)在妇科实践中:一种治疗少经少经的方法
Pub Date : 2021-12-30 DOI: 10.31254/jahm.2021.7406
V. Monisha, Anuradha Roy, Binay Sen
Artavakshaya (oligo-hypomenorrhoea) is a condition described in Ayurvedic classics in which vitiated vata and kapha dosha causes obstruction in the artavavahasrotas (channels that carries menstrual blood or artava). The characteric features of Artavakshaya include yathochitakalaadarshana (prolonged intermenstrual period), alpata (scanty bleeding) and yonivedana (pain in vagina or pain during menses). Artavakshaya is a condition very much similar to the oligohypomenorrhoea which is characterized by cycle which are longer than 35 days and with bleeding less than 2 days. The principles of management of Artavakshaya are vatakaphashamaka (vata and kapha dosha pacifying) and agnivardhaka (stimulant, digestive and pitta analogue) therapy. Basti (medicated enema) which comes under Panchakarma (five biopurificatory measures) is considered as superior treatment in vata and vata predominant conditions. Matrabasti (low dose medicated oil enema) is a type of anuvasana basti (medicated lipid enema) which can be administered without much contraindication. Matrabasti administered with vatakaphashamaka and agnivardhaka drug can be better choice in the treatment of artavakshaya. Basti which is administered through guda maarga (rectal route) reaches the pakwashaya (large intestine) and spreads the virya (potency) of the drug to sarvasharira (whole body) through the microchannels. Basti which can act on the enteric nervous system and thereby act on the Central Nervous System can further stimulate the Hypothalamo-Pituitary-Ovarian (HPO) axis. A well co-ordinated HPO axis can normalise the menstrual cycle.
少经血症(少经血症)是阿育吠陀经典中描述的一种情况,在这种情况下,vata和kapha dosha被破坏,导致aravavahasrotas(经血或经血的通道)阻塞。Artavakshaya的特征包括yathochitakalaadarshana(月经间期延长),alpata(少量出血)和yonivedana(阴道疼痛或月经期间疼痛)。阿尔塔瓦克沙雅是一种非常类似于少经的情况,其特点是周期超过35天,出血少于2天。治疗的原则是vatakapashamaka (vata和kapha dosha安抚)和agnivardhaka(刺激、消化和皮塔类似物)疗法。属于Panchakarma(五种生物净化措施)的basi(药物灌肠)被认为是vata和vata主要条件下的优越治疗方法。Matrabasti(低剂量药油灌肠)是一种无禁忌症的anuvasana basi(药油灌肠)。Matrabasti与vatakapashamaka和agnivardhaka药物联合使用是治疗aravakshaya的较好选择。Basti通过guda maarga(直肠途径)到达pakwashaya(大肠),并通过微通道将药物的virya(效力)传播到sarvasharira(全身)。Basti可以作用于肠神经系统,从而作用于中枢神经系统,进一步刺激下丘脑-垂体-卵巢(HPO)轴。协调良好的HPO轴可以使月经周期正常化。
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引用次数: 1
Pharmacognostical Investigation on Fruits of Apium graveolens L.: An Ayurvedic Herb 阿育吠陀草药荆芥果实的生药学研究
Pub Date : 2021-12-30 DOI: 10.31254/jahm.2021.7404
D. Iyer, M. Soni, V. Mulchandani, N. Siddiqui
Herbs are the resources of biologically or pharmacologically active components that are conventionally used to treat various ailments. Apium graveolens is being significantly used in “Ayurvedic system of medicine”. Since these medicinal herbs are collected by untutored personals on the basis of their Sanskrit/ local names, there occurs a great chance of confusion or misidentification due to unawareness and related vernacular names. To assist exact and effortless recognition of drugs, Pharmacognostical characters involving macroscopical, microscopical and physiochemical parameters were studied. This helped in studying quality control parameters for sample identification with determination of their quality and purity.
草药是生物或药理活性成分的资源,通常用于治疗各种疾病。“阿育吠陀医学体系”中大量使用了凤尾草。由于这些草药是由未经指导的人根据其梵语/当地名称收集的,因此由于不了解和相关的白话名称,很有可能出现混淆或错误识别。为了准确、方便地识别药物,研究了其生药学特征,包括宏观、微观和理化参数。这有助于研究样品鉴定的质量控制参数,并确定其质量和纯度。
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引用次数: 0
Effect of Tarpan and Rsayana Churna in the Management of Computer Vision Syndrome: An Evidence based Clinical Study Tarpan和Rsayana Churna在计算机视觉综合征治疗中的作用:基于证据的临床研究
Pub Date : 2021-09-30 DOI: 10.31254/jahm.2021.7309
Sarvesh Kumar, Gunjan Sharma, A. Verma
The world in the new millennium is having Computer vision syndrome as a new complaint. Trividha Hetu i.e. Astamendriyarth Samyoga, Pragyaparadha (distortion from the moral values); and Parinama (Time) is basic Ayurveda fundamental for every disease pathogenesis. In reference of CVS, improper use of visual sensory organ leads to Digital stress injury similar to Astamendriyarth Samyoga, intellectual distortion of human acts i.e. Pragyaparadha and new millennium disease i.e. Parinam. Computer, suddenly change “the distance dominant” world into the complete “near point world’’. This change emerged visual disorder in form of vision-related discomfort, ocular fatigue, and systemic effects. Computer Vision Syndrome is identified as digital eye strain group of visual, ocular, and systemic symptoms caused by prolonged and improper use of Video Display Terminal (VDT). Blueprints recommended by Acharya Vagbhatt and Charaka for such types of disorders indicate that CVS can be assumed as Vata-Pittaja ocular cum systemic disease. So, topical therapy along with systemic therapy should be including for curative measures of CVS. The use of Rasayana Churna for oral intake and Phaltrikadi-Ghrita Netra Tarpana for topical therapy was tried among 20 patients of CVS distributed in two groups. In group I, combined treatment i.e oral and local therapy was given, shows the significant improvement in visual, ocular and systemic symptoms of CVS. While in groups II only oral treatment was given and shows significant results only on systemic symptoms of CVS. The outcome of study established CVS as a Vata-Pittaja visual, ocular as well as systemic disorder according to Ayurvedic perspective. So the overall treatment includes systemic health booster therapy combination with topical ocular medication gives the promising results for CVS management.
在新千年的世界里,计算机视觉综合症正成为一种新的抱怨。Trividha Hetu,即Astamendriyarth Samyoga, Pragyaparadha(道德价值观的扭曲);而Parinama(时间)是阿育吠陀每一种疾病发病机制的基础。参考CVS,视感觉器官使用不当导致类似Astamendriyarth Samyoga的数字应激性损伤、人类行为的智力扭曲(Pragyaparadha)和新千年病(Parinam)。计算机,突然把“距离主导”的世界变成了完整的“近点世界”。这种变化以视觉相关不适、眼疲劳和全身影响的形式出现视觉障碍。计算机视觉综合征是由于长时间和不当使用视频显示终端(VDT)而引起的视觉、眼部和全身症状的数字眼疲劳组。Acharya Vagbhatt和Charaka推荐的这类疾病的蓝图表明,CVS可以被认为是Vata-Pittaja眼部和全身疾病。因此,局部治疗和全身治疗应包括治疗措施CVS。将20例CVS患者分为两组,分别口服Rasayana Churna和外用Phaltrikadi-Ghrita Netra Tarpana。在第一组中,给予口服和局部联合治疗,CVS的视觉、眼部和全身症状均有显著改善。而在第二组中,仅给予口服治疗,并且仅对CVS的全身性症状有显著效果。根据阿育吠陀的观点,研究结果确定CVS是一种Vata-Pittaja视觉、眼部和全身疾病。因此,综合治疗包括全身健康促进疗法和局部眼部药物治疗,对CVS的治疗有很好的效果。
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引用次数: 0
Clinical Evaluation of Unani formulation in Gastritis- A Pilot Study 乌尼尼方治疗胃炎的临床评价-一项初步研究
Pub Date : 2021-09-30 DOI: 10.31254/jahm.2021.7310
T. Nayak, Farooqui Shazia Parveen, M. Ahad, S. Bano
Background and objectives: Gastritis is a painful or inflammatory state of the stomach and the mucosa covering it. The most common cause of gastritis is helicobacter pylorus. It is caused by certain infection, or by the routine use of antiinflammatory painkiller. Unani Physician has identified various medicinal products in classical text indicated for the treatment of gastritis. Therefore, a clinical trial was conducted to evaluate the clinical efficacy and safety of Unani Formulation in gastritis on scientific parameters. Methods: The study was designed as single blind pilot study on 12 patients of gastritis. Unani Formulation (Amla-2 part, Asl-Us-Soos-2 part, and Badiyan-2part) was given in the form of powder at the dose of 6 g twice a day after meal for the period of 28 days. All the patients of were assessed weekly on subjective parameters (at 0, 7th, 14th , 21th, and 28th day) whereas objective parameters were assessed before and after the treatment. The outcome of intervention was analyzed using appropriate statistical methods. Results: The study effects on subjective parameters like pain in abdomen, epigastric burning, nausea & vomiting and early satiety were found significantly reduced significantly. The objective parameter VAS and 5 PLS was found highly significant when compared before and after with p<0.0001. The results were analyzed after using paired ‘t’ test. Interpretation & Conclusion: The findings about the both parameters (subjective and objective) that the ‘Unani Formulation is effective gastritis and the cure was significant. Safety parameters (SGOT, SGPT, Blood Urea and Serum Creatinine) were remains unchanged. Therefore, it can be concluded that the Unani Formulation is safe and effective in management of gastritis.
背景和目的:胃炎是胃及其粘膜的疼痛或炎症状态。胃炎最常见的病因是幽门螺杆菌。它是由某种感染或常规使用抗炎止痛药引起的。乌纳尼医师在经典文献中确定了用于治疗胃炎的各种药物。为此,本研究通过科学参数评价乌尼方治疗胃炎的临床疗效和安全性。方法:采用单盲先导研究方法,对12例胃炎患者进行研究。乌拉尼制剂(Amla-2部分、asl - us - sos -2部分、巴地炎2部分)为粉剂,剂量为6 g,每日2次,餐后给药,连用28天。所有患者在治疗前和治疗后进行每周一次的主观参数评估(第0、7、14、21、28天),客观参数评估。采用适当的统计学方法对干预结果进行分析。结果:研究对腹部疼痛、上腹部烧灼感、恶心呕吐、早期饱腹感等主观参数的影响明显降低。客观参数VAS和5 PLS与前后比较,p<0.0001,具有高度显著性。采用配对t检验对结果进行分析。解释与结论:乌尼方对胃炎有效,治疗效果显著。安全性参数(SGOT、SGPT、尿素和血清肌酐)保持不变。由此可见,乌尼尼方治疗胃炎安全有效。
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引用次数: 0
A clinical study to evaluate the efficacy of Shatyadi Yoga in the treatment of Tamak Shwasa (Bronchial Asthma): Single case study 评价Shatyadi瑜伽治疗支气管哮喘疗效的临床研究:单例研究
Pub Date : 2021-09-30 DOI: 10.31254/jahm.2021.7308
Amandeep Kaur, D. K. Goyal, Arun Sharma
Bronchial Asthma is a chronic inflammatory disease of the Respiratory airways characterized by an increased responsiveness of the tracheobronchial tree to a variety of stimuli. In ayurveda Tamak Shwasa vyadhi is related with the derangement of the Pranavaha Shrotas. Tamak Shwasa is Pittasthana Samudhabhava and Kapha Vataja dosha vyadhi. The proposed study was conducted to access the efficacy of Shatyadi Yoga in the management of Tamak Shwasa. In modern science, there is no permanent cure for Bronchial Asthma.That is why it is the necessity to search for safe and effective herbal yoga in Asthma. The drug Shatyadi Yoga indicate the dominance of Katu, Tikta and Kashaya rasa, Laghu, Tikshna Guna, Ushna virya and Vata Kapha shamak karma. Shatyadi Yoga act on Pranvaha Shrotas thereby pacifying the symptoms in Tamak Shwasa.
支气管哮喘是一种慢性呼吸道炎症性疾病,其特征是气管支气管树对各种刺激的反应性增加。在阿育吠陀中,Tamak Shwasa vyadhi与Pranavaha Shrotas的紊乱有关。Tamak Shwasa是Pittasthana Samudhabhava和Kapha Vataja dosha vyadhi。提出的研究是为了获得Shatyadi瑜伽在Tamak Shwasa管理中的功效。在现代科学中,支气管哮喘没有永久性的治疗方法。这就是为什么在哮喘中寻找安全有效的草药瑜伽是必要的。药物Shatyadi瑜伽表明Katu, Tikta和Kashaya rasa, Laghu, Tikshna Guna, Ushna virya和Vata Kapha shamak业力的主导地位。Shatyadi瑜伽对Pranvaha Shrotas起作用,从而缓解Tamak Shwasa的症状。
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引用次数: 0
Sandhigatvata: A Case Report Sandhigatvata:一个案例报告
Pub Date : 2021-09-30 DOI: 10.31254/jahm.2021.7306
R. Khajuria
Sandhigata vata is a Vata dominating disorders which creates inflammatory as well as degenerative changes in joints. The condition is more painful when mobile joints like Janusandhi (knee joint) of the body are involved in Sandhigata Vata. The disease Sandhigata Vata is more prone to be affected the knee joint because it is most frequently involved joint in daily routine work. Knee joint is weight bearing joints among all joints so, more prevalence in overweight patients. In the pathogenesis of Sandhigata Vata it is found dominance of Vata Dosha. In the current study the main aim to evaluate the efficacy of Janu basti with Til tail in Sandhigatvata.
Sandhigata vata是一种vata主导疾病,它在关节中产生炎症和退行性变化。当身体的活动关节,如Janusandhi(膝关节)涉及到Sandhigata Vata时,这种情况会更痛苦。膝关节是日常工作中最常累及的关节,故更易发病。膝关节是所有关节中的承重关节,因此,在超重患者中发病率更高。在梵散的发病机制中,发现梵散的主导地位。本研究的主要目的是评价带Til尾的山茱萸对山茱萸的治疗效果。
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引用次数: 1
A Recent Update on the Pharmacognostical as well as Pharmacological Profiles of the Acacia catechu Heartwood: A Mini Review 儿茶相思心材的生药学和药理研究进展综述
Pub Date : 2021-09-30 DOI: 10.31254/jahm.2021.7304
P. Sharma, Raju Lingha
Acacia Catechu L. (Fabaceae) has been drastically utilized in holistic drug alongside way of the Austronesia for ancient history many thousand years before. The whole plant of the A. Catechu is acquired a comprehensive variety of medicinal potential such as antioxidant, anti-inflammatory, antibacterial, antifungal, astringent, anthelmintics, analgesic, anti-diabetic, wound healing, anti- tumors, immune booster, etc. Chemical examination of this widely growing plant is manifested that it accommodates very high amounts of the tannin, flavonoids, and phenolic compounds, especially catechin/ epicatechin, epigallocatechin, quercetin, taxifolin & procyanidin, etc. The presence of these active compounds is to be shown the drug is to possess an excellent antioxidant, anti-inflammatory, astringent & anti-diabetic outcome. The heartwood of this plant is to give a medicinally potent product is known as Katha having a wide range of therapeutic potential. The prime phytoconstituents of the heartwood are catechin or epicatechin/ catechin exists in this plant performs an important function such as antioxidant, anti-inflammatory, antimicrobial & anticancer potential. Due to the wide range of the medicinal activity of the A. Catechu heartwood, it may have a wide area of research. This review only focuses only on the recent update on the Pharmacognostical as well as pharmacological Profiles of the A. Catechu Heartwood.
儿茶(豆科)在几千年前的古代史上就与南岛群岛一起被广泛地用作整体药物。儿茶全株具有抗氧化、抗炎、抗菌、抗真菌、收敛、驱虫药、镇痛、抗糖尿病、伤口愈合、抗肿瘤、免疫增强等多种综合药用潜力。对这种广泛生长的植物的化学检查表明,它含有大量的单宁、黄酮类化合物和酚类化合物,特别是儿茶素/表儿茶素、表没食子儿茶素、槲皮素、杉木素和原花青素等。这些活性化合物的存在表明,该药物具有优异的抗氧化、抗炎、收敛和抗糖尿病的效果。这种植物的心材是一种有效的药用产品,被称为卡塔,具有广泛的治疗潜力。心材的主要植物成分是儿茶素或表儿茶素/儿茶素,存在于该植物中,具有抗氧化、抗炎、抗菌和抗癌等重要功能。由于儿茶心材具有广泛的药用活性,因此可能具有广泛的研究领域。本文仅对近年来有关儿茶心材生药学和药理研究的最新进展进行综述。
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引用次数: 4
The Use of Medicinal Plants in Digestive System Related Disorders- A Systematic Review 药用植物在消化系统相关疾病中的应用综述
Pub Date : 2021-09-30 DOI: 10.31254/jahm.2021.7303
H. S. Cheema, Mitra Pal Singh
The most prevalent forms of ailments affecting a huge number of individuals throughout the world are digestive system problems. According to the World Health Organization (WHO), over 100 million people died globally as a result of digestive system diseases in 2012. Despite this, most scientific bodies disregard the relevance of a healthy digestive system and associated problems in health debates. Food and lifestyle have a direct influence on digestive health, and a healthy diet or a change in lifestyle can address a variety of issues. Plants provide a variety of phytochemicals and nutraceuticals that may aid in the treatment and prevention of a number of digestive problems. Plant-based remedies, including spices, are widely used by ordinary people across the world and can help digestion without causing adverse effects. Numerous ethnomedicinal studies show that the use of medicinal plants by traditional populations to treat digestive problems is widespread across the world. The biological activities of traditional herbal medicine used to treat digestive problems have been studied and generally indicate minimal side effects. However, as the demand for herbal medicines derived from plants grows across the world, more comprehensive clinical research on the advantages and toxicity of herbal medicines should be conducted. The goal of this study is to provide examples of research that have established and verified the use of plant-based medicines to treat digestive problems. In particular, traditional medicinal plant extracts or phytochemicals that have been shown to reduce symptoms of digestive system disorders along with mode of action and safety will be discussed.
影响世界上许多人的最普遍的疾病是消化系统问题。根据世界卫生组织(世卫组织)的数据,2012年全球有超过1亿人死于消化系统疾病。尽管如此,大多数科学机构在健康辩论中忽视了健康消化系统和相关问题的相关性。食物和生活方式对消化系统健康有直接影响,健康的饮食或生活方式的改变可以解决各种问题。植物提供各种各样的植物化学物质和营养保健品,可以帮助治疗和预防许多消化问题。包括香料在内的植物性疗法被世界各地的普通人广泛使用,可以帮助消化而不会造成不良影响。许多民族医学研究表明,传统人群使用药用植物治疗消化问题在世界各地都很普遍。用于治疗消化问题的传统草药的生物活性已经被研究过,通常表明副作用很小。然而,随着世界范围内对植物来源的草药需求的增长,需要对草药的优势和毒性进行更全面的临床研究。本研究的目的是提供已经建立和验证使用植物性药物治疗消化问题的研究实例。特别是,传统药用植物提取物或植物化学物质已被证明可以减轻消化系统紊乱的症状,以及作用方式和安全性将被讨论。
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引用次数: 7
Phytochemical Screening and Analgesic activity study of different solvent fractions of Aerial parts of Operculina turpethum (L.) 红花地上部不同溶剂组分的植物化学筛选及镇痛活性研究
Pub Date : 2021-09-30 DOI: 10.31254/jahm.2021.7302
U. Karmakar, Sonya Akter, S. Sheikh
Preliminary phytochemical analysis of ethanol extract of the aerial parts of Operculina turpethum L. (Family: Convolvulaceae) exhibited the presence of reducing sugar, phenolic compounds, tannins, flavonoids, carbohydrate, glycosides, alkaloids, acidic compounds, steroids, saponin, and terpenoids. The ethanolic crude extract showed significant (p<0.0001) peripheral analgesic activity at the doses of 250 mg/kg (26.47% writhing inhibition) and 500 mg/kg (50.74% writhing inhibition) determined by acetic acid induced writhing reflex in mice as compared to control Diclofenac sodium (77.94%). After solvent fractionation, n-Hexane, ethyl acetate, butanol and water fraction of Operculina turpethum showed 58.82%, 39.70%, 30.14%, and 20.58% writhing inhibition respectively at the dose of 500 mg/kg body weight. Different phytochemicals present in the extract might be responsible for biological activities found with this study. This research could form the basis of further investigation including pure compounds isolation.
对旋花科(Convolvulaceae)地上部乙醇提取物进行了初步的植物化学分析,发现其中含有还原糖、酚类化合物、单宁、黄酮类化合物、碳水化合物、糖苷、生物碱、酸性化合物、类固醇、皂苷和萜类化合物。乙醇粗提物在250 mg/kg(26.47%扭体抑制)和500 mg/kg(50.74%扭体抑制)剂量下,醋酸诱导小鼠扭体反射,与对照双氯芬酸钠(77.94%)相比,其外周镇痛活性显著(p<0.0001)。经溶剂分馏后,在500 mg/kg体重剂量下,正己烷、乙酸乙酯、丁醇、水馏分对大鼠扭曲的抑制作用分别为58.82%、39.70%、30.14%、20.58%。提取物中存在的不同植物化学物质可能负责本研究中发现的生物活性。本研究可为进一步的研究奠定基础,包括化合物的纯化。
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引用次数: 0
期刊
Journal of Ayurvedic and Herbal Medicine
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