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Germination study in Gokhru (Pedalium murex L.) seeds 木犀草种子萌发研究
Pub Date : 2022-03-25 DOI: 10.31254/jahm.2022.8106
A. Bhuker, V. Mor, P. Ms, S. Jakhar
Gokhru (Pedalium murex L.) is one of the important medicinal plants propagated through seeds but no germination test has been standardized for this crop yet. Germination test is mandatory for seeds sale which is required for labelling. The fruits of Pedalium murex L. are four angled indehiscent hard pyramidal with four sharp spines and it is very difficult to extract the seeds from fruits. Hence, study was conducted to find out suitable method and optimum temperature for germination test of fruits as well as seeds of gokhru. The study was conducted by using three germination testing methods viz., Top of Paper (TP), Between Paper (BP) and Sand (S) methods and three temperatures i.e. 25, 30 and one alternating temperature of 20-30℃. The results revealed that during germination test of fruits, ‘Sand’ method showed superiority by registering maximum germination (29.67%) over ‘Between Paper’ (23.33%) and ‘Top of Paper’ (3.11%) methods. Viogur index-I (213) and Vigour Index-II (2.20) were also observed maximum in ‘Sand’ method while maximum seedling length (8.00cm) and seedling dry weight (0.075mg) were observed in ‘Between Paper’ method. Among the temperatures, maximum germination (22.78 & 36.00%), seedling length (8.00 & 9.44cm), seedling dry weight (0.142 & 0.077mg), Vigour index-I (186 &341) and Vigour index-II (2.26 & 2.79) were observed at 30℃ in fruits and seeds respectively. No germination was recorded below 20℃. Good germination was observed in seeds compared to fruits. In case of seeds, maximum germination (38.33%), seedling length (9.00cm), seedling dry weight (0.076mg), vigour index-I (329) and vigour index-II (2.77) were recorded in ‘Between Paper’ method. It is concluded that 30℃ temperature is optimum for germination test of both seed as well as fruit in Gokhru and ‘Sand’ method is best for fruit germination test while in case of germination test of seeds ‘Between Paper’ method is best.
龙葵(Pedalium murex L.)是一种重要的通过种子繁殖的药用植物,但目前尚无标准化的发芽试验。发芽测试是强制性的种子销售,需要标签。其果实呈四棱不裂的硬锥形,有四尖刺,从果实中提取种子非常困难。为此,研究了果品和种子发芽试验的适宜方法和最佳温度。采用纸顶法(TP)、纸沙间法(BP)三种萌发试验方法,在25℃、30℃和20 ~ 30℃交变温度下进行萌发试验。结果表明,在果实萌发试验中,“沙法”的发芽率最高(29.67%),高于“纸间法”(23.33%)和“纸顶法”(3.11%)。“沙”法的幼苗生长指数和活力指数分别为213和2.20,“纸间”法的幼苗长和干重分别为8.00cm和0.075mg。在不同温度下,果实和种子的最高发芽率分别为22.78%和36.00%,苗长分别为8.00和9.44cm,干重分别为0.142和0.077mg,活力指数为i(186和341)和ii(2.26和2.79)。在20℃以下无萌发记录。与果实相比,种子萌发良好。以种子为例,“纸间法”测得最大发芽率(38.33%)、苗长(9.00cm)、苗干重(0.076mg)、活力指数i(329)和活力指数ii(2.77)。结果表明,30℃的温度对种子和果实的萌发都是最适宜的,对果实的萌发试验以“沙”法最好,对种子的萌发试验以“纸间”法最好。
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引用次数: 0
Leucas aspera Spreng (Dronapushpi): A Review
Pub Date : 2022-03-25 DOI: 10.31254/jahm.2022.8111
S. Hiremath, Pradeep, Ashwini Jeerankalagi
Leucas aspera is a plant species belongs to the genus Leucas and the family Lamiaceae. Species has different common names depending its location and most commonly known as Tumbai or Thumba, is distributed throughout India from the Himalayas down to Ceylon. It is known for its various uses in the fields of medicine and agriculture. This article aims to provide a comprehensive review on the pharmacognostic, phytochemical, and pharmacological aspects of Leucas aspera.Traditionally different parts of the plants are used as an antipyretic, insecticide, stimulant, emmenagogue, expectorant, aperient and diaphoretic. Leaves are found to be useful in chronic rheumatism, chronic skin eruptions specially in psoriasis. In case of snake bite, bruised leaves are applied locally. The plant mainly contains triterpenoids, oleanolic acid, b-sitosterol, diterpenes, ursolic acid, nicotine, sterols, glucoside and phenolic compounds. The plant, flower extract and essential oil shows various activities like antioxidant, anti-microbial, anti-fungal and antinociceptive etc.
柳杉(Leucas aspera)是柳杉科柳杉属植物。物种有不同的共同名称取决于其位置,最常见的是Tumbai或Thumba,分布在整个印度,从喜马拉雅山脉到锡兰。它以其在医学和农业领域的各种用途而闻名。本文旨在对其生药学、植物化学和药理方面的研究进行综述。传统上,这种植物的不同部分被用作解热、杀虫剂、兴奋剂、催泻剂、祛痰剂、通便剂和发汗剂。叶子被发现对慢性风湿病,慢性皮肤疹,特别是牛皮癣有用。如遇蛇咬伤,可在局部涂抹擦伤的叶子。该植物主要含有三萜、齐墩果酸、b-谷甾醇、二萜、熊果酸、尼古丁、甾醇、葡萄糖苷和酚类化合物。植物、花卉提取物和精油具有抗氧化、抗微生物、抗真菌和抗伤等多种活性。
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引用次数: 0
In-vitro and in-vivo supportive research on medicinal properties of Cannabis sativa: A comprehensive review 大麻药用特性的体外和体内支持性研究综述
Pub Date : 2022-03-25 DOI: 10.31254/jahm.2022.8110
P. Perera, J. I. D. Diddeniya
Cannabis sativa is an herbaceous plant which is mainly used as a remedy for neurological, digestive and immunological ailments in traditional medicine. Even though Cannabis is the most illicit plant around the world, its medicinal properties are beneficial in number of ways. Numerous beneficial effects of C. sativa have been demonstrated in multiple in-vitro and in-vivo studies from different parts of the world. The aim of this paper was to systematically review the literature and provide a summary on potential medicinal benefits of C. sativa. This systematic review was conducted by using the data bases; Science direct and PubMed for studies published from 1st of January 2015 to 31st of October 2020. In order to obtain further data, a manual search was also carried out from the reference lists of included articles. After removing the duplicate articles 77 total number of articles included in this present review. The beneficial health effects of C. sativa were anti-inflammatory, analgesic, anti-microbial, anti-parasitic, anti-oxidant and anti-cancer properties. In addition, it revealed that C. sativa lower blood glucose, serum cholesterol and blood pressure levels. Apart from that, the use of Cannabis in other diseases such as irritable bowel disease, renal diseases, neurofibromatosis, and leucorrhea was also identified. The wide range of medicinal effects may be due to main active ingredients of Tetrahydro cannabinol, Cannabidiol, Cannabinol and Tetrahydro cannabivarin. Available in-vitro and invivo evidence suggested that C. sativa has many favorable health effects and further randomized controlled clinical trials will be needed to determine these effects thoroughly.
大麻是一种草本植物,在传统医学中主要用于治疗神经、消化和免疫疾病。尽管大麻是世界上最非法的植物,但它的药用特性在很多方面都是有益的。来自世界各地的多种体外和体内研究已经证明了苜蓿的许多有益作用。本文系统地综述了苜蓿的相关文献,并对其潜在的药用价值进行了综述。本系统评价采用数据库进行;Science direct和PubMed检索2015年1月1日至2020年10月31日期间发表的研究。为了获得进一步的数据,还从纳入文章的参考文献列表中进行了人工检索。除去重复的文章后,本综述纳入的文章总数为77篇。苜蓿具有抗炎、镇痛、抗微生物、抗寄生虫、抗氧化和抗癌的有益保健作用。此外,研究还发现苜蓿具有降低血糖、血清胆固醇和血压水平的作用。除此之外,还确定了大麻在肠易激病、肾病、神经纤维瘤病和白带等其他疾病中的使用。四氢大麻酚、大麻二酚、大麻酚和四氢大麻素的主要有效成分可能具有广泛的药效。现有的体外和体内证据表明,苜蓿有许多有益的健康作用,需要进一步的随机对照临床试验来彻底确定这些作用。
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引用次数: 3
Effect of Ilaj Bil Ghiza (Dieto-Therapy) in Dyslipidemia Management- A Case Study Ilaj Bil Ghiza(饮食疗法)在血脂异常管理中的作用-一个案例研究
Pub Date : 2022-03-25 DOI: 10.31254/jahm.2022.8101
Farooqui Shazia Parveen, M. Quamri, Khaleel Ahmed
Background: Dyslipidemia is a significant modifiable risk factor for cardiovascular disease. In type 2 diabetes mellitus (T2DM) patients, elevated low-density lipoprotein cholesterol (LDL-C) levels were associated with an increased risk of ischemic stroke and an increased risk of cardiovascular mortality independent of LDL-C levels. The nutritional needs of the body have been met based on demand, and pharmacotherapy has been avoided to protect the body from any side effects or adverse effects. Methods: This paper is a case study of patient with high lipid profile level. Patient recommended opting Dieto-therapy with modulation in dietary habits for one month with fortnightly follow up for routine check-up. Results: After one month of changing his diet pattern in terms of quality and quantity, his lipid profile started to improve. Conclusions: It is fair to conclude that the concept of dieto-therapy in UMS has a solid base for confirming safe and effective in the management of dyslipidemia.
背景:血脂异常是心血管疾病的重要可改变危险因素。在2型糖尿病(T2DM)患者中,低密度脂蛋白胆固醇(LDL-C)水平升高与缺血性卒中风险增加和心血管死亡风险增加相关,与LDL-C水平无关。身体的营养需求已经根据需要得到满足,并且避免了药物治疗,以保护身体免受任何副作用或不利影响。方法:以高血脂患者为研究对象。患者建议选择饮食疗法并调整饮食习惯一个月,每两周随访一次常规检查。结果:在改变饮食质量和数量一个月后,患者的血脂水平开始改善。结论:可以公平地得出这样的结论:饮食疗法在UMS中的概念为确认在血脂异常的管理中安全有效提供了坚实的基础。
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引用次数: 0
Statistical Interpretation of Anumana Pramana with Special Reference to Linga Paramarsha- A Review 特别参考Linga Paramarsha的Anumana Pramana的统计解释综述
Pub Date : 2022-03-25 DOI: 10.31254/jahm.2022.8108
C. Biswas
Anumana means the cognition coming in to being after perception or Paramarsha. Inference is an important source of knowledge in the field of diagnosis and treatment. The symptoms described by the patient help the physician to interrogate further and to infer about the disease. Here the Anumana and Linga Paramarsha are correlated with some related modern medical statistical terminology. The present review study carried out by collecting the literature and research finding from various classical and modern text book online reports and online research articles in Google Search and PubMed Database. It is revealed that the Linga Paramarsha and its adnexa have got the prime role to establish the Anumana Pramana. The terminology as Vyapti, Pakshya, Vyapak, Hetu and Linga Paramarsha represents the statistical explanation of invariable correlation, sample, state of possession, concomitant relation, proof and proper consideration or reference respectively. Medical statistics is an essential concept to accomplish the Anumana Pramana in the purview of Linga Paramarsha Linga Paramarsha. is an essential tool in clinical practice as well as in Ayurvedic research.
Anumana意指在知觉或Paramarsha之后产生的认知。推理是诊断和治疗领域知识的重要来源。病人描述的症状有助于医生进一步询问和推断疾病。这里Anumana和Linga Paramarsha与一些相关的现代医学统计术语相关联。本综述研究通过收集谷歌搜索和PubMed数据库中各种古典和现代教科书在线报告和在线研究文章的文献和研究发现进行。据透露,林伽帕拉马沙及其附属机构在建立阿努玛那帕拉马纳方面发挥了主要作用。Vyapti、Pakshya、Vyapak、Hetu和Linga Paramarsha等术语分别代表了不变相关性、样本、占有状态、伴随关系、证明和适当考虑或参考的统计解释。医学统计是在Linga Paramarsha的职权范围内完成Anumana Pramana的基本概念。是临床实践和阿育吠陀研究的重要工具。
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引用次数: 0
Review on Reverse Pharmacology of Jawarhar Mahakashaya Drugs for Anti-pyretic Activity in Momoherbal and Polyherbal Form 贾瓦哈尔大哈沙亚单方和多方解热药物的反向药理学研究综述
Pub Date : 2022-03-25 DOI: 10.31254/jahm.2022.8109
R. Pandit, A. Upadhayaya, Chandni Gupta, Sunil Sharma
Ayurvedic Jawarahara Mahakashaya (JhMh) includes Sariva, Sharkara, Patha, Manjishtha, Draksha, Pilu, Parushaka, Abhaya, Amalaka and Bibhitaka drugs as a set of ten herbal drugs, means this set of drug is effective in countering Jawar (fever) in single drug form or combined formulation. Globally the most accepted drugs which are used to cure pyrexia are NSAIDS. It is reported that most of these chemical antipyretic formulations has been associated with gastrointestinal, renal, hepatic, CNS and dermatological side effects. Extensive literature searches both electronic online databases on concerning issues. Drugs of Jawarhar Mahakashaya in monoherbal and polyherbal form have shown significant antipyretic activity in pre-clinical set up as mentioned in Ayurvedic literatures. The main aim of this paper is to review reverse pharmacology of JhMh drugs is described in terms of Ayurveda and is supported parallelly with the facts and findings of scientific researches done in modern science. JhMh can replace the side effects of chemical drugs and stand as sustainable antipyretics if used judicious.
阿育吠陀Jawarahara Mahakashaya (JhMh)包括Sariva, Sharkara, Patha, Manjishtha, Draksha, Pilu, Parushaka, Abhaya, Amalaka和Bibhitaka药物作为一组十种草药,这意味着这套药物以单一药物形式或联合配方有效对抗发烧。在全球范围内,最被接受的治疗发热的药物是非甾体抗炎药。据报道,这些化学解热制剂大多与胃肠道、肾脏、肝脏、中枢神经系统和皮肤方面的副作用有关。广泛的文献搜索有关问题的电子在线数据库。阿育吠陀文献中提到的Jawarhar Mahakashaya单草药和多草药形式的药物在临床前设置中显示出显着的解热活性。本文的主要目的是回顾JhMh药物的反向药理学,从阿育吠陀的角度进行描述,并与现代科学研究的事实和发现相支持。如果使用得当,JhMh可以取代化学药物的副作用,成为可持续的退烧药。
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引用次数: 1
Perception about Suvarna Prashana in parents– A multi centric cross-sectional study 父母对小动作的感知——一项多中心横断面研究
Pub Date : 2022-03-25 DOI: 10.31254/jahm.2022.8107
Bhinde Sagar M, Karishma Narvani, H. Jani
Background: Suvarna Prashana (SP) word comes in Kashyapa Samhita only, but use of Suvarna (gold) is mentioned by every Acharya starting from neonatal age. SP increase the intelligence and immunity, and hence used in paediatric age group since long back. Due to competitive nature of education in current days, parents want their child to be bright in education. At the same time, COVID 19 pandemic has revealed the importance of immunity to everyone and parents are in search of immune-modulatory medicine for their children. Vidyabharti in collaboration with Kamdhenu Divya Aushadhi Mahila Sahkari Mandali, Jamnagar are doing work in this field with SP and hence to document the perception of parents for this formulation (SP), this cross sectional study was planned. Material and method: Google forms were provided to 1523 parents of 37 centers, whose child had received this SP at least for 1 year (13 doses) on every Pushya constellation, out of whom 1348 parents had responded. Data were analysed to get the idea about perception of parents for this formulation. Results: Response failure was 11.5%. 94.8% parents found this practice beneficial. 98.52% parents would like to recommend this to other parents. 92.80% and 97.77% parents found their child’s memory and growth and development improved after SP respectively. Family member of 34.64% children were infected with COVID 19 out of which, only 3.41 % children got infected during this study period. Conclusion: Survey study found that most parents believed/perceived that SP provided during every Pushya constellation at least for one year, is beneficial in regards to improvement in memory, general health, immunity of their children. Hence this preliminary data from observational study pave the way to establish the effectiveness of this drug in children through future randomized control trial.
背景:Suvarna Prashana (SP)这个词只出现在Kashyapa Samhita中,但从新生儿开始,每个Acharya都提到了Suvarna(黄金)的使用。SP能提高智力和免疫力,因此很早以前就用于儿科年龄组。由于当今教育的竞争性质,父母希望他们的孩子在教育中聪明。与此同时,COVID - 19大流行揭示了免疫力对每个人的重要性,父母们正在为孩子寻找免疫调节药物。Vidyabharti与Kamdhenu Divya Aushadhi Mahila Sahkari Mandali, Jamnagar在这一领域与SP合作,因此,为了记录父母对这种配方(SP)的看法,计划进行这项横断面研究。材料和方法:向37个中心的1523名家长提供了谷歌表格,他们的孩子在每个Pushya星座上接受了至少1年(13剂)的SP,其中1348名家长做出了回应。对数据进行了分析,以了解家长对这一配方的看法。结果:有效率为11.5%。94.8%的家长认为这种做法有益。98.52%的家长愿意向其他家长推荐。92.80%和97.77%的家长认为SP后孩子的记忆和生长发育有所改善。34.64%的儿童家庭成员感染了COVID - 19,其中仅3.41%的儿童在本研究期间感染。结论:调查研究发现,大多数家长相信/认为在每个普什亚星座提供至少一年的SP,对改善孩子的记忆、整体健康和免疫力有益。因此,观察性研究的初步数据为未来通过随机对照试验确定该药在儿童中的有效性铺平了道路。
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引用次数: 0
Ayurveda treatment as black box design in the management of Visarpa- Retrospective case study 阿育吠陀治疗在Visarpa管理中的黑箱设计-回顾性案例研究
Pub Date : 2022-03-25 DOI: 10.31254/jahm.2022.8103
K. N. Chaitralakshmi, S. Gaonkar, Swathi Lata
Visarpa is one of skin disease explained by most of the Acharyas. A 24-years old female came to Panchakarma OPD of Dhanvantari Ayurveda College Hospital and Research Centre, Siddapur, Uttara Kannada. With the complaints of blisters on the right-side of neck, severe burning sensation, itching, severe pricking pain, redness, pus formation for 3 days. She was successfully treated with external applications and internal medications with Tikta (bitter), Kashaya (astrigent) and Sheeta (cool) drugs. This case study demonstrates that acute condition of Visarpa can be managed well in short duration with Ayurvedic medicines.
Visarpa是大多数阿查里亚人解释的皮肤病之一。一名24岁女性来到北卡纳达邦Siddapur的Dhanvantari阿育吠陀学院医院和研究中心Panchakarma OPD。主诉颈部右侧起水泡,剧烈烧灼感,瘙痒,剧烈刺痛,发红,脓液形成3天。她成功地通过外部应用和内部药物治疗,包括Tikta(苦)、Kashaya(紧)和Sheeta(凉)药物。本案例研究表明,阿育吠陀药物可以在短时间内很好地治疗急性维萨帕。
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引用次数: 0
Efficacy of Classical Siddha Formulations in the treatment of Peru Manjal Noi w.s.r to Jaundice 经典释迦方治疗黄疸的疗效观察
Pub Date : 2022-03-25 DOI: 10.31254/jahm.2022.8102
Sivaranjani Kumarasmy, Kiruthika Ramkumar
Background: Jaundice (Icterus) is a condition in which there is retention of bile pigments in the tissues as a result of liver disease, biliary obstruction, haemolysis or combination of all. In Yugi Vaithiya Chinthamani Jaundice can be correlated with Peru Manjal Noi with yellowish discolouration of urine, eyes, tongue, and body. Classical Siddha formulations were used in this study to reduce the biliary load, progression of disease as well as to provide symptomatic relief. Case presentation: A 52 years old male patient visited Outpatient department of Siddha Clinical Research Unit, Palayamkottai with the following complaints of Generalized weakness,Loss of appetite,Nausea on and off, Abdominal pain on and off, Yellowish discolouration of skin and eyes, Yellowish discolouration of urine since 15 days. Conclusion: Symptomatic relief was observed within 7 days of treatment and biochemical changes were observed within 16 days of treatment. A further randomized controlled clinical study has to be carried out to validate this study.
背景:黄疸是一种由于肝脏疾病、胆道阻塞、溶血或所有这些原因导致的组织中胆汁色素潴留的疾病。在Yugi Vaithiya Chinthamani,黄疸可与秘鲁Manjal Noi相关,尿液、眼睛、舌头和身体呈黄色变色。在本研究中使用经典的悉达配方来减少胆道负荷,疾病进展以及提供症状缓解。病例介绍:一名52岁男性患者到Palayamkottai Siddha临床研究中心门诊就诊,主诉为全身无力、食欲不振、断断性恶心、断断性腹痛、皮肤和眼睛黄变、尿液黄变15天。结论:治疗7 d内症状缓解,16 d内生化变化。需要进一步的随机对照临床研究来验证该研究。
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引用次数: 0
Determination of Bioactive compounds in the leaf extract of Phyllanthus niruri, Emblica officinalis and Psoralea corylifolia 余甘子、山楂和补骨脂叶提取物中生物活性成分的测定
Pub Date : 2022-03-25 DOI: 10.31254/jahm.2022.8104
S. Kumar, K. Chozhan, K. Murugesh
A major part of the total populace relies upon the conventional plant based medicines. The study was carried out to determine the bioactive compounds in the botanicals viz., Phyllanthus niruri, Emblica officinalis and Psoralea corylifolia through phytochemical screening tests and to estimate the total phenol and flavonoid contents in three botanicals. The results of the phytochemical screening tests indicate the presence of phenols, tannin, flavonoids, saponins, terpenoids, steroids and alkaloids. Phytochemicals from medicinal plants/some botanicals are likely to possess many pharmacological activities such as antioxidant, anti-inflammatory, anti-cancer, antimicrobial effects against various pathogens. The Total Phenol content in Phyllanthus niruri is 115 mg/g and with flavonoid value 70.15 mg/g. The Flavonoid content in Emblica officinalis was found to be 22.52 mg/g. The value varies from plants to plants and the results clearly indicate that plants are rich in various phytochemicals components and it will be more advantage to use these botanicals as natural medicine compared with chemical drugs.
大部分人口依赖传统的植物性药物。本研究通过植物化学筛选试验,测定了三种植物药——百lanthus niruri、Emblica officinalis和Psoralea coryliolia的生物活性成分,并对三种植物药的总酚和总黄酮含量进行了估算。植物化学筛选试验的结果表明,存在酚类、单宁、黄酮类、皂苷、萜类、类固醇和生物碱。药用植物/某些植物化合物可能具有抗氧化、抗炎、抗癌、抗菌等多种药理活性。余甘子总酚含量为115 mg/g,总黄酮含量为70.15 mg/g。黄酮含量为22.52 mg/g。不同植物的价值不同,结果清楚地表明植物富含各种植物化学成分,将这些植物成分作为天然药物使用比化学药物更有优势。
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引用次数: 1
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Journal of Ayurvedic and Herbal Medicine
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