Chronic obstructive pulmonary disease (COPD) is characterized by consistent airway obstruction, which is mainly caused by bronchoconstriction and airway inflammation. Two recommended medications, tiotropium bromide (TIO) and roflumilast, exert their pharmacological effects of bronchodilation and anti-inflammation respectively. This review's purpose is to elucidate two drug therapies, TIO and roflumilast for COPD comprehensively, therefore their pharmacodynamic, pharmacology and pharmacokinetic properties are reviewed. Both once-daily administration of tiotropium and roflumilast demonstrate improvement of patients’ lung function, suggesting their good potency to treat COPD.
{"title":"The Analysis of Tiotropium bromide and Roflumilast: Two Potent Medications for Chronic Obstructive Pulmonary Disease","authors":"Yuanzi Xu","doi":"10.1145/3570773.3570833","DOIUrl":"https://doi.org/10.1145/3570773.3570833","url":null,"abstract":"Chronic obstructive pulmonary disease (COPD) is characterized by consistent airway obstruction, which is mainly caused by bronchoconstriction and airway inflammation. Two recommended medications, tiotropium bromide (TIO) and roflumilast, exert their pharmacological effects of bronchodilation and anti-inflammation respectively. This review's purpose is to elucidate two drug therapies, TIO and roflumilast for COPD comprehensively, therefore their pharmacodynamic, pharmacology and pharmacokinetic properties are reviewed. Both once-daily administration of tiotropium and roflumilast demonstrate improvement of patients’ lung function, suggesting their good potency to treat COPD.","PeriodicalId":153475,"journal":{"name":"Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129753621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
By view of the dataset from 1986 to 1990 on the Jiaozhou Bay waters, being able to analyze the vertical distribution of Hg in Jiaohzou Bay, the vertical change of the sedimentation of Hg, the change in water effects. Therefore, the author put forward Yang Dongfang model on the variation patterns of Hg content in both surface and bottom waters. The vertical distribution changes of Hg content in Jiaozhou Bay from 1986 to 1990 adequately unveiled the sedimentation process of Hg as it was deposited constantly and rapidly on the seabed. With the analysis of the surveys carried out from 1986 to 1990, we found that the water effects of Hg varied in different seasons. In spring, Hg content in surface waters represented dilution effects on the seabed. In the summer of the same year, the Hg in surface waters was diluted on the seabed but it was sometimes accumulated there. In the autumn of the same year, both dilution effects and accumulative effects appeared on the seabed and finally the two effects turned out to become dilution effect only.
{"title":"The effect of Hg content in water bodies for precision medicine of Hg disease","authors":"Dongfang Yang, Zaibin Chang","doi":"10.1145/3570773.3570876","DOIUrl":"https://doi.org/10.1145/3570773.3570876","url":null,"abstract":"By view of the dataset from 1986 to 1990 on the Jiaozhou Bay waters, being able to analyze the vertical distribution of Hg in Jiaohzou Bay, the vertical change of the sedimentation of Hg, the change in water effects. Therefore, the author put forward Yang Dongfang model on the variation patterns of Hg content in both surface and bottom waters. The vertical distribution changes of Hg content in Jiaozhou Bay from 1986 to 1990 adequately unveiled the sedimentation process of Hg as it was deposited constantly and rapidly on the seabed. With the analysis of the surveys carried out from 1986 to 1990, we found that the water effects of Hg varied in different seasons. In spring, Hg content in surface waters represented dilution effects on the seabed. In the summer of the same year, the Hg in surface waters was diluted on the seabed but it was sometimes accumulated there. In the autumn of the same year, both dilution effects and accumulative effects appeared on the seabed and finally the two effects turned out to become dilution effect only.","PeriodicalId":153475,"journal":{"name":"Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128616205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiajia Fan, W. Yue, Renjun Cai, Dian-Cheng Tang, Tao Liu, Qiu-ling Xu
Objective: To explore the mechanism of acupuncture in guanyuan, sanyinjiao and zusanli for the treatment of primary dysmenorrhea based on bioinformatics and network topology methods. Methods: The targets of acupuncture at guanyuan (CV4), sanyinjiao (SP6) and zusanli (ST36) were retrieved using the PubMed database. The targets related to primary dysmenorrhea were collected using GeneCards database. The common targets of acupuncture and primary dysmenorrhea were obtained by using VENN diagram and used to establish a protein-protein interaction (PPI) network in the STRING database. Cytoscape software (version 3.9.1) was used to screen the key targets in PPI networks. Gene Ontology (GO) functional enrichment and Kyoto Genome Encyclopedia (KEGG) were used to obtain correspongding pathway analysis and visualization. Results: 24 intersection targets of acupuncture CV4, SP6, ST36 and primary dysmenorrhea were screened, and 10 key targets were screened, which were IL6, IL1B, STAT3, TP53, CXCL8, POMC, AKT1, PTGS2, VEGFA and IL17A. Go function enrichment analysis yielded 169 biological processes (BP), 17 molecular functions (MF) and 9 cellular component (CC). KEGG pathway enrichment screening yielded 93 signal pathways. Conclusion: Acupuncture treatment of primary dysmenorrhea involves multiple targets and pathways. Acupuncture may exert therapeutic effects on primary dysmenorrhea through TNF signaling pathway, cAMP signaling pathway, IL-17 signaling pathway, HIF-1 signaling pathway, Pi3k-akt signaling pathway and MAPK Signaling pathway via affecting inflammatory response, platelet aggregation and improving hypoxia.
{"title":"A bioinformatics-based approach to study the mechanism of acupuncture for primary dysmenorrhea","authors":"Jiajia Fan, W. Yue, Renjun Cai, Dian-Cheng Tang, Tao Liu, Qiu-ling Xu","doi":"10.1145/3570773.3570839","DOIUrl":"https://doi.org/10.1145/3570773.3570839","url":null,"abstract":"Objective: To explore the mechanism of acupuncture in guanyuan, sanyinjiao and zusanli for the treatment of primary dysmenorrhea based on bioinformatics and network topology methods. Methods: The targets of acupuncture at guanyuan (CV4), sanyinjiao (SP6) and zusanli (ST36) were retrieved using the PubMed database. The targets related to primary dysmenorrhea were collected using GeneCards database. The common targets of acupuncture and primary dysmenorrhea were obtained by using VENN diagram and used to establish a protein-protein interaction (PPI) network in the STRING database. Cytoscape software (version 3.9.1) was used to screen the key targets in PPI networks. Gene Ontology (GO) functional enrichment and Kyoto Genome Encyclopedia (KEGG) were used to obtain correspongding pathway analysis and visualization. Results: 24 intersection targets of acupuncture CV4, SP6, ST36 and primary dysmenorrhea were screened, and 10 key targets were screened, which were IL6, IL1B, STAT3, TP53, CXCL8, POMC, AKT1, PTGS2, VEGFA and IL17A. Go function enrichment analysis yielded 169 biological processes (BP), 17 molecular functions (MF) and 9 cellular component (CC). KEGG pathway enrichment screening yielded 93 signal pathways. Conclusion: Acupuncture treatment of primary dysmenorrhea involves multiple targets and pathways. Acupuncture may exert therapeutic effects on primary dysmenorrhea through TNF signaling pathway, cAMP signaling pathway, IL-17 signaling pathway, HIF-1 signaling pathway, Pi3k-akt signaling pathway and MAPK Signaling pathway via affecting inflammatory response, platelet aggregation and improving hypoxia.","PeriodicalId":153475,"journal":{"name":"Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126865724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Chinese Traditional Medicine (CTM) Bushen formula is found to downregulate the expression of Regulatory T cells (Treg-cells) in chronic Hepatitis B (CHB) patients. This paper investigates the effects of Astragaloside IV, one substance the Bushen formula contains, on HBV induced Treg-cell transformation in animal models. Mice will be injected with HBV and grown for 3 months to simulate CHB patients. Astragaloside IV will be tested on dose-dependency by administering different quantities of the substance. There are two major types of possible results for the effects of Astragaloside IV on the expression of Treg-cells: (1) Astragaloside IV does downregulate Treg-cells, (2) Astragaloside IV does not downregulate Treg-cells. Astragalus mongholicus, the source of Astragaloside IV, is one of the many plants often used in CTM. This study will provide us with more details on the mechanisms which CTM treats diseases by analyzing at a molecular level.
{"title":"Astragaloside IV May Bind to CD25 Gene to Repress HBV Induced Regulatory T Cell Expression","authors":"Kr Wang","doi":"10.1145/3570773.3570831","DOIUrl":"https://doi.org/10.1145/3570773.3570831","url":null,"abstract":"The Chinese Traditional Medicine (CTM) Bushen formula is found to downregulate the expression of Regulatory T cells (Treg-cells) in chronic Hepatitis B (CHB) patients. This paper investigates the effects of Astragaloside IV, one substance the Bushen formula contains, on HBV induced Treg-cell transformation in animal models. Mice will be injected with HBV and grown for 3 months to simulate CHB patients. Astragaloside IV will be tested on dose-dependency by administering different quantities of the substance. There are two major types of possible results for the effects of Astragaloside IV on the expression of Treg-cells: (1) Astragaloside IV does downregulate Treg-cells, (2) Astragaloside IV does not downregulate Treg-cells. Astragalus mongholicus, the source of Astragaloside IV, is one of the many plants often used in CTM. This study will provide us with more details on the mechanisms which CTM treats diseases by analyzing at a molecular level.","PeriodicalId":153475,"journal":{"name":"Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120941007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jackson He, Yi-Jyun Chen, Zhi Feng Etan Kiang, Ly Yang
While prior therapies for malignant solid tumors mostly focused on surgical excision and/or chemotherapy/radiotherapy, it is now feasible to combat cancers via monitoring and manipulating the immune system. Hence, the main purpose of this work is to hypothesize a potential combinational therapy with prospective enhancements to Chimeric Antigen Receptor T cells, a provision of anticipated results in vivo immune compromised Rat model with Non-Hodgkin's Lymphoma. This study, based on previously done research, it suggests the inclusion of Synnotch Receptor, which can manage T cell exhaustion and alter antigen recognition by on/off switching the receptors, particularly adjusting for CD19 and supplementary CD22, CD20, and CD30. In addition to Synnotch, this work suggests that PGC1a and GLUT 1 be upregulated to deal with the problem of poor persistence in the tumor microenvironment, monitored by western blot and flow cytometry during experiments, and in addition, with the application of GM-CSF for tackling cytokine release syndrome.
{"title":"Non-Hodgkin Lymphoma CAR T Cells: Enhancement on Synnotch Signaling, GLUT1 expression, and PGC1a expression brings Potential Clinical Advancement in Therapy","authors":"Jackson He, Yi-Jyun Chen, Zhi Feng Etan Kiang, Ly Yang","doi":"10.1145/3570773.3570825","DOIUrl":"https://doi.org/10.1145/3570773.3570825","url":null,"abstract":"While prior therapies for malignant solid tumors mostly focused on surgical excision and/or chemotherapy/radiotherapy, it is now feasible to combat cancers via monitoring and manipulating the immune system. Hence, the main purpose of this work is to hypothesize a potential combinational therapy with prospective enhancements to Chimeric Antigen Receptor T cells, a provision of anticipated results in vivo immune compromised Rat model with Non-Hodgkin's Lymphoma. This study, based on previously done research, it suggests the inclusion of Synnotch Receptor, which can manage T cell exhaustion and alter antigen recognition by on/off switching the receptors, particularly adjusting for CD19 and supplementary CD22, CD20, and CD30. In addition to Synnotch, this work suggests that PGC1a and GLUT 1 be upregulated to deal with the problem of poor persistence in the tumor microenvironment, monitored by western blot and flow cytometry during experiments, and in addition, with the application of GM-CSF for tackling cytokine release syndrome.","PeriodicalId":153475,"journal":{"name":"Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences","volume":"740 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116120150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
According to the survey data on the waters of Jiaozhou Bay from 1986 to 1990, in the terms of space, through analysis on the data about Hg content every year, including the degree of content, the horizontal, vertical and seasonal distribution, we studied the sources, distribution and migration of Hg, and the water quality of Jiaozhou Bay and obtained the migration patterns of Hg. In terms of time, through the discussion on the data of Hg content during five consecutive years from 1986 to 1990, we determined the changes happened in time and space of Hg content and obtained following results: (1) the changing process of Hg in years and mouths and its model; (2) the changing process of sources of Hg on the basis of time and space. Those patterns and changing process based on time and space laid a solid theoretical foundation of the migration process of Hg in water bodies.
{"title":"The spatial migration pattern of Hg content for the prediction of disease during a long time","authors":"Dongfang Yang, Dan Tian","doi":"10.1145/3570773.3570877","DOIUrl":"https://doi.org/10.1145/3570773.3570877","url":null,"abstract":"According to the survey data on the waters of Jiaozhou Bay from 1986 to 1990, in the terms of space, through analysis on the data about Hg content every year, including the degree of content, the horizontal, vertical and seasonal distribution, we studied the sources, distribution and migration of Hg, and the water quality of Jiaozhou Bay and obtained the migration patterns of Hg. In terms of time, through the discussion on the data of Hg content during five consecutive years from 1986 to 1990, we determined the changes happened in time and space of Hg content and obtained following results: (1) the changing process of Hg in years and mouths and its model; (2) the changing process of sources of Hg on the basis of time and space. Those patterns and changing process based on time and space laid a solid theoretical foundation of the migration process of Hg in water bodies.","PeriodicalId":153475,"journal":{"name":"Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115277109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Accurate cell segmentation and counting play an important role in medical diagnosis. However, the size and shape of cells are varied largely, and the presence of overlapping cells complicates cell counting. Recent studies have shown that multi-task learning methods perform well in deep learning. In specific, we design Multi-task Segmentation Regression Counting Network (MSRCN). For cell segmentation, a multi-scale attention mechanism module is designed to suppress irrelevant regions and learns salient features for a specific task. For cell counting, a regression model is utilized to learn a mapping from cell feature information to target counts. The proposed MSRCN model is analyzed and compared with other states of the art cell segmentation methods and cell counting methods. MSRCN outperforms these methods in all evaluation metrics. The Dice similarity coefficient, root mean square error, and mean absolute error of the proposed method is 0.9316, 2.1215, and 1.5927, respectively. The experiments results show that the proposed method not only improves the functioning of cell segmentation, but also outperforms direct regression counting methods in terms of cell counting.
{"title":"MSRCN: Multi-task Learning Network for Cell Segmentation and Regression Counting","authors":"Lihua Huang, Liqin Huang, Mingjing Yang","doi":"10.1145/3570773.3570816","DOIUrl":"https://doi.org/10.1145/3570773.3570816","url":null,"abstract":"Accurate cell segmentation and counting play an important role in medical diagnosis. However, the size and shape of cells are varied largely, and the presence of overlapping cells complicates cell counting. Recent studies have shown that multi-task learning methods perform well in deep learning. In specific, we design Multi-task Segmentation Regression Counting Network (MSRCN). For cell segmentation, a multi-scale attention mechanism module is designed to suppress irrelevant regions and learns salient features for a specific task. For cell counting, a regression model is utilized to learn a mapping from cell feature information to target counts. The proposed MSRCN model is analyzed and compared with other states of the art cell segmentation methods and cell counting methods. MSRCN outperforms these methods in all evaluation metrics. The Dice similarity coefficient, root mean square error, and mean absolute error of the proposed method is 0.9316, 2.1215, and 1.5927, respectively. The experiments results show that the proposed method not only improves the functioning of cell segmentation, but also outperforms direct regression counting methods in terms of cell counting.","PeriodicalId":153475,"journal":{"name":"Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences","volume":"49 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121006533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yajin Huang, Yanjun Liu, Junqiang Li, Yan Yue, Yaqing Liu, Tiancheng Wang
Electrophysiological investigations of sleep provide an important advantage for recording spontaneous neural activity and quantifying brain function. This study combined artificial intelligence technology to quantitatively analyze spindle density in adult patients with epilepsy. All patients received one-night sleep electroencephalogram monitoring. We employed a convolutional neural network-based sleep staging system to predict sleep macrostructure. Then we applied two species of advanced algorithms: Spindler and Latent state spindle detector, to automatically detect sleep spindle during non-rapid eye movement sleep stage 2. And we calculated three kinds of frequency range spindle density involving 11-17 Hz, 9-12 Hz, and 12-15 Hz. Our results suggested that 11-17 Hz and 12-15 Hz spindle density in adult epilepsy predominated in parietal and 9-12 Hz spindle density in prefrontal regions.
睡眠电生理研究为记录自发神经活动和量化脑功能提供了重要的优势。本研究结合人工智能技术对成人癫痫患者的纺锤体密度进行定量分析。所有患者均接受一晚睡眠脑电图监测。我们采用基于卷积神经网络的睡眠分期系统来预测睡眠宏观结构。然后应用Spindler和Latent state spindle detector两种先进算法，对非快速眼动睡眠阶段2的睡眠纺锤波进行自动检测。计算了11- 17hz、9- 12hz和12- 15hz三种频率范围的主轴密度。结果表明，成人癫痫患者11-17 Hz和12-15 Hz纺锤波密度主要分布在顶叶区，9-12 Hz纺锤波密度主要分布在前额叶区。
{"title":"Spindle Density Analysis of Adult Epilepsy based on Automatic Detection Algorithms in EEG","authors":"Yajin Huang, Yanjun Liu, Junqiang Li, Yan Yue, Yaqing Liu, Tiancheng Wang","doi":"10.1145/3570773.3570804","DOIUrl":"https://doi.org/10.1145/3570773.3570804","url":null,"abstract":"Electrophysiological investigations of sleep provide an important advantage for recording spontaneous neural activity and quantifying brain function. This study combined artificial intelligence technology to quantitatively analyze spindle density in adult patients with epilepsy. All patients received one-night sleep electroencephalogram monitoring. We employed a convolutional neural network-based sleep staging system to predict sleep macrostructure. Then we applied two species of advanced algorithms: Spindler and Latent state spindle detector, to automatically detect sleep spindle during non-rapid eye movement sleep stage 2. And we calculated three kinds of frequency range spindle density involving 11-17 Hz, 9-12 Hz, and 12-15 Hz. Our results suggested that 11-17 Hz and 12-15 Hz spindle density in adult epilepsy predominated in parietal and 9-12 Hz spindle density in prefrontal regions.","PeriodicalId":153475,"journal":{"name":"Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences","volume":"109 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121774393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Many empirical studies have shown that Internet-based psychological intervention is effective in treating depression. In recent years, a large number of related studies have been accumulated, but there is a lack of organization. This paper reviews and summarizes the relevant research (including systematic review, randomized controlled trial and meta-analysis) in CNKI and Web of Science databases, expounds the application of Internet-based psychological intervention in the treatment of depression from both theoretical and practical aspects, and prospects the future research work.
许多实证研究表明，基于网络的心理干预对抑郁症的治疗是有效的。近年来，相关的研究已经积累了大量，但缺乏组织。本文对中国知网和Web of Science数据库的相关研究(包括系统综述、随机对照试验和荟萃分析)进行了综述和总结，从理论和实践两个方面阐述了基于互联网的心理干预在抑郁症治疗中的应用，并对未来的研究工作进行了展望。
{"title":"The application of Internet-based intervention in the treatment of depression","authors":"Miaoyun Xie, Runqing Gao, Kesui Deng","doi":"10.1145/3570773.3570846","DOIUrl":"https://doi.org/10.1145/3570773.3570846","url":null,"abstract":"Many empirical studies have shown that Internet-based psychological intervention is effective in treating depression. In recent years, a large number of related studies have been accumulated, but there is a lack of organization. This paper reviews and summarizes the relevant research (including systematic review, randomized controlled trial and meta-analysis) in CNKI and Web of Science databases, expounds the application of Internet-based psychological intervention in the treatment of depression from both theoretical and practical aspects, and prospects the future research work.","PeriodicalId":153475,"journal":{"name":"Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133238066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: From the advantages of acupuncture analgesia, to explore the effect of different acupuncture moxibustion therapies on sciatica in modern clinical research and visual analysis of point selection through the method of data mining technology, to select the optimal therapy and point selection for clinical service. Methods: Based on data mining technology, statistical analysis was carried out on the clinical efficacy and acupoints of different acupuncture and moxibustion treatments for sciatica in Chinese and English literatures in recent 10 years. Finally, according to the results of statistical analysis, the best moxibustion therapy and acupoints for the treatment of sciatica were selected. Conclusion: In all the included literatures, the average total effective rate of special acupuncture treatment is the highest among the seven treatment methods, followed by acupuncture + traditional Chinese medicine and warm acupuncture. In all the included literatures, the top ten acupoints used were GB30, BL40, GB34, BL57, BL60, BL54, BL25, EX-B2, BL23, GB39 and BL37. In the co-occurrence network diagram, there is a strong correlation between GB30, GB34, BL40, BL54, BL57, BL60 and other acupoints, which can be selected preferentially for treatment.
{"title":"Analysis of curative effect and point selection of different acupuncture treatments for sciatica based on data mining technology","authors":"Renjun Cai, Jia-rong Fan, Fengyuan Bai, Dian-Cheng Tang, Tao Liu, Qiu-ling Xu","doi":"10.1145/3570773.3570858","DOIUrl":"https://doi.org/10.1145/3570773.3570858","url":null,"abstract":"Objective: From the advantages of acupuncture analgesia, to explore the effect of different acupuncture moxibustion therapies on sciatica in modern clinical research and visual analysis of point selection through the method of data mining technology, to select the optimal therapy and point selection for clinical service. Methods: Based on data mining technology, statistical analysis was carried out on the clinical efficacy and acupoints of different acupuncture and moxibustion treatments for sciatica in Chinese and English literatures in recent 10 years. Finally, according to the results of statistical analysis, the best moxibustion therapy and acupoints for the treatment of sciatica were selected. Conclusion: In all the included literatures, the average total effective rate of special acupuncture treatment is the highest among the seven treatment methods, followed by acupuncture + traditional Chinese medicine and warm acupuncture. In all the included literatures, the top ten acupoints used were GB30, BL40, GB34, BL57, BL60, BL54, BL25, EX-B2, BL23, GB39 and BL37. In the co-occurrence network diagram, there is a strong correlation between GB30, GB34, BL40, BL54, BL57, BL60 and other acupoints, which can be selected preferentially for treatment.","PeriodicalId":153475,"journal":{"name":"Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133616169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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