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Occurrence of periodontal diseases according to the ACES 2018 Classification Framework and the CDC/AAP definition: A cross-sectional study in a major Brazilian city 根据 ACES 2018 分类框架和 CDC/AAP 定义的牙周病发生率:巴西某大城市的横断面研究
IF 5.8 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-21 DOI: 10.1111/jcpe.14035
Stefany Duarte dos Anjos, Tayse Caroline Cunha de Medeiros, Rafael Milani Ferro, Leticia Daufenbach, Raquel Santos de Oliveira, Anna Carolina Neves Leutz, Marina David Joao Pereira, Alex Nogueira Haas, Alessandra Areas e Souza, Joao Paulo Steffens

Aim

The occurrence of periodontal diseases is still to be determined in large samples of major Brazilian cities. This study aimed to assess the periodontal status of adults from Curitiba, Paraná, Brazil, using periodontitis definitions by the Centers for Disease Control and Prevention and the American Academy of Periodontology (CDC/AAP) and the recently published ACES 2018 Classification Framework.

Materials and Methods

A multi-stage probability sampling technique was applied to draw individuals aged 18 or older. A total of 566 individuals underwent a full-mouth periodontal examination. Periodontitis cases were defined according to the CDC/AAP and the ACES 2018 Classification Framework. Non-periodontitis cases were classified as healthy or gingivitis. The agreement between the two definitions was calculated.

Results

Periodontal health was present in 33.6% and 13.8% of individuals, and gingivitis was found in 11.7% and 7.5%, according to CDC/AAP and ACES, respectively. Mild, moderate and severe periodontitis (CDC/AAP) were present in 2.1%, 33.4% and 19.1% of individuals, respectively. Using ACES, 34.3% had Stages I/II and 43.3% had Stages III/IV. The occurrence of periodontitis was higher when a subgroup of individuals aged 30+ were analysed, ranging from 69.6% (CDC/AAP) to 90.1% (ACES). CDC/AAP and ACES agreement for health, gingivitis and periodontitis accounted for 68.8% of the observations.

Conclusions

Periodontal diseases affect more than 66% of the population aged 18+ years. Classic definition by the CDC/AAP and the recently published ACES Framework yielded moderate agreement.

目的:巴西主要城市的大样本牙周病发生率仍有待确定。本研究旨在评估巴西巴拉那州库里蒂巴市成年人的牙周状况,采用的是美国疾病控制与预防中心和美国牙周病学会(CDC/AAP)的牙周炎定义以及最近发布的 ACES 2018 分类框架。共有 566 人接受了全口牙周检查。牙周炎病例根据 CDC/AAP 和 ACES 2018 分类框架进行定义。非牙周炎病例被归类为健康或牙龈炎。结果根据CDC/AAP和ACES,分别有33.6%和13.8%的人存在牙周健康,11.7%和7.5%的人存在牙龈炎。轻度、中度和重度牙周炎(CDC/AAP)分别占 2.1%、33.4% 和 19.1%。使用 ACES 时,34.3% 的人处于 I/II 期,43.3% 的人处于 III/IV 期。在对 30 岁以上的人群进行分析时,牙周炎的发生率更高,从 69.6%(CDC/AAP)到 90.1%(ACES)不等。CDC/AAP 和 ACES 就健康、牙龈炎和牙周炎达成的一致意见占观察结果的 68.8%。美国疾病预防控制中心/美国牙科协会的经典定义与最近发布的 ACES 框架基本一致。
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引用次数: 0
Higher haemoglobin levels are associated with impaired periodontal status 血红蛋白水平越高,牙周状况越差。
IF 5.8 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-14 DOI: 10.1111/jcpe.14030
Atte Tapiola, Joona Tapio, Hannu Vähänikkilä, Paula Tegelberg, Pekka Ylöstalo, Peppi Koivunen

Aim

Cellular oxygen sensing mechanisms have been linked to periodontal condition, and levels of haemoglobin (Hb) (the main carrier of oxygen) can be used as a surrogate measure for hypoxia. We aimed to examine relations between Hb levels and key periodontal health parameters in a general population.

Materials and Methods

The population comprised 1711 (47% male) subjects from the Northern Finland Birth Cohort 1966, for whom an oral health examination was carried out at 46 years of age and whose Hb levels were within the Finnish reference values. Relative risks (RRs) were estimated using Poisson regression models.

Results

The low-Hb tertile (mean Hb 133 g/L) had healthier anthropometric, metabolic and periodontal health parameters than the high-Hb tertile (mean Hb 151 g/L). Multivariable regression models adjusted for risk factors showed Hb levels to be positively associated with alveolar bone loss (ABL) and periodontal pocket depth (PPD), although the associations were weaker after adjustment for key metabolic parameters and were strongly influenced by smoking status.

Conclusions

Hb levels within the normal variation are positively associated with PPD and ABL. The association between Hb levels and periodontal condition appeared to be more complex than had previously been anticipated.

目的:细胞氧传感机制与牙周状况有关,血红蛋白(Hb)(氧气的主要载体)水平可作为缺氧的替代测量指标。我们旨在研究普通人群中血红蛋白水平与牙周健康主要参数之间的关系:研究对象包括来自 1966 年北芬兰出生队列的 1711 名受试者(47% 为男性),他们在 46 岁时接受了口腔健康检查,其 Hb 水平在芬兰参考值范围内。采用泊松回归模型估算了相对风险(RR):结果:低 Hb 三分层(平均 Hb 133 g/L)的人体测量、代谢和牙周健康参数比高 Hb 三分层(平均 Hb 151 g/L)更健康。根据风险因素调整的多变量回归模型显示,血红蛋白水平与牙槽骨损失(ABL)和牙周袋深度(PPD)呈正相关,但在调整主要代谢参数后,相关性减弱,且受吸烟状况的影响较大:结论:正常范围内的 Hb 水平与 PPD 和 ABL 呈正相关。结论:正常变异范围内的 Hb 水平与 PPD 和 ABL 呈正相关。Hb 水平与牙周状况之间的关联似乎比之前预期的更为复杂。
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引用次数: 0
The flapless approach with and without enamel matrix derivatives for the treatment of intrabony defects: A randomized controlled clinical trial 使用和不使用釉质基质衍生物的无瓣法治疗骨内缺损:随机对照临床试验。
IF 5.8 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-10 DOI: 10.1111/jcpe.14028
Mario Aimetti, Morta Stasikelyte, Giulia Maria Mariani, Luca Cricenti, Giacomo Baima, Federica Romano

Aim

To compare the clinical and radiographic outcomes of flapless procedure alone or in combination with enamel matrix derivatives (EMD) in the treatment of deep intrabony defects.

Materials and Methods

Forty-six patients re-evaluated after non-surgical therapy were randomly assigned to the test (flapless with EMD) or control group (flapless alone). Clinical measurements were recorded pre-surgery and at 6 and 12 months after surgery, and radiographic measurements were taken pre-surgery and after 12 months.

Results

Forty-six patients completed the study. Improvements were observed in both groups at 12 months for mean clinical attachment level (CAL) gain, with significant differences between test (3.9 ± 1.1 mm) and control groups (3.0 ± 1.2) (p = .017). Probing pocket depth (PPD) reduction (4.0 ± 0.7 vs. 3.3 ± 1.4 mm) was also near to statistical significance (p = .051). Also, more sites achieved successful composite outcome measure (final PPD ≤ 4 mm and CAL gain ≥3 mm) for the regenerative treatment in the flapless + EMD group (82.6% vs. 52.2%; p = .028). In terms of radiographic outcomes, EMD yielded a greater defect bone fill than flapless treatment alone (3.0 ± 1.0 mm vs. 1.8 ± 1.5 mm; p < .001).

Conclusions

The additional application of EMD during the flapless procedure for intrabony defects slightly improved clinical and radiographic outcomes. ClinicalTrials.gov identification number: NCT05456555.

目的:比较无瓣手术单独或联合釉基质衍生物(EMD)治疗深部骨内缺损的临床和放射学效果:46名经过非手术治疗后重新评估的患者被随机分配到试验组(无瓣联合EMD)或对照组(单独无瓣)。记录手术前、手术后 6 个月和 12 个月的临床测量结果,并在手术前和 12 个月后进行放射学测量:结果:46 名患者完成了研究。试验组(3.9 ± 1.1 mm)和对照组(3.0 ± 1.2)在 12 个月后的平均临床附着水平(CAL)均有改善,差异显著(p = .017)。探诊袋深度(PPD)的减少(4.0 ± 0.7 vs. 3.3 ± 1.4 mm)也接近统计学意义(p = .051)。此外,在无瓣+EMD组中,更多部位的再生治疗取得了成功的综合结果(最终PPD≤4毫米,CAL增大≥3毫米)(82.6% vs. 52.2%;p = .028)。在放射学结果方面,EMD 比单独的无瓣治疗产生了更大的缺损骨填充(3.0 ± 1.0 mm vs. 1.8 ± 1.5 mm; p 结论:EMD 比单独的无瓣治疗产生了更大的缺损骨填充(3.0 ± 1.0 mm vs. 1.8 ± 1.5 mm; p):在无瓣治疗骨内缺损过程中额外应用 EMD 稍微改善了临床和放射学结果:NCT05456555。
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引用次数: 0
Elevated neutrophil extracellular trap levels in periodontitis: Implications for keratinization and barrier function in gingival epithelium 牙周炎中中性粒细胞胞外捕获物水平升高:对牙龈上皮角质化和屏障功能的影响。
IF 5.8 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-05 DOI: 10.1111/jcpe.14025
Ya-yun Cui, Yi-heng Yang, Jia-yi Zheng, Hui-hui Ma, Xue Han, Chong-shan Liao, Min Zhou

Aim

To explore the levels of neutrophil extracellular traps (NETs) in patients with periodontitis and examine their effects on keratinization, barrier function of human gingival keratinocytes (HGKs) and the associated mechanisms.

Materials and Methods

Saliva, gingival crevicular fluid (GCF), clinical periodontal parameters and gingival specimens were collected from 10 healthy control subjects and 10 patients with stage II–IV periodontitis to measure the NET levels. Subsequently, mRNA and protein levels of keratinization and barrier indicators, as well as intracellular calcium and epithelial barrier permeability, were analysed in HGKs after NET stimulation.

Results

The study showed that NET levels significantly elevated in patients with periodontitis, across multiple specimens including saliva, GCF and gingival tissues. Stimulation of HGKs with NETs resulted in a decrease in the expressions of involucrin, cytokeratin 10, zonula occludens 1 and E-cadherin, along with decreased intracellular calcium levels and increased epithelial barrier permeability. Furthermore, the inhibition of keratinization by NETs is ERK-KLF4-dependent.

Conclusions

This study indicates that NETs impair the barrier function of HGKs and suppress keratinization through ERK/KLF4 axis. These findings provide potential targets for therapeutic approaches in periodontitis to address impaired gingival keratinization.

目的:探讨牙周炎患者体内中性粒细胞胞外捕获物(NETs)的水平,并研究其对人牙龈角质形成、人牙龈角质形成细胞(HGKs)屏障功能的影响及其相关机制:收集10名健康对照组和10名II-IV期牙周炎患者的唾液、龈沟液(GCF)、临床牙周参数和牙龈标本,测量NET水平。随后,分析了NET刺激后HGKs中角化和屏障指标的mRNA和蛋白质水平,以及细胞内钙和上皮屏障通透性:研究结果表明,在包括唾液、GCF 和牙龈组织在内的多种样本中,牙周炎患者的 NET 水平明显升高。用NET刺激HGKs会导致内含蛋白、细胞角蛋白10、闭锁带1和E-cadherin的表达减少,同时细胞内钙水平降低,上皮屏障通透性增加。此外,NETs对角质化的抑制是ERK-KLF4依赖性的:本研究表明,NETs会损害HGKs的屏障功能,并通过ERK/KLF4轴抑制角质化。这些发现为牙周炎的治疗方法提供了潜在靶点,以解决牙龈角质化受损的问题。
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引用次数: 0
Do systemic amoxicillin and metronidazole during the non-surgical peri-implantitis treatment phase prevent the need for future surgical treatment? A retrospective long-term cohort study 在种植体周围炎的非手术治疗阶段,全身使用阿莫西林和甲硝唑是否能避免将来的手术治疗?一项回顾性长期队列研究。
IF 5.8 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-04 DOI: 10.1111/jcpe.14024
Jarno Hakkers, Tine E. Vangsted, Arie Jan van Winkelhoff, Yvonne C. M. de Waal

Aim

The aim of this retrospective long-term follow-up of a 3-month RCT was to assess whether non-surgical peri-implantitis treatment with adjunctive systemic antibiotics influenced the need for additional surgical treatment.

Materials and Methods

Patients enrolled in an aftercare programme following non-surgical peri-implantitis treatment, with or without systemic amoxicillin and metronidazole, were analysed. Data had previously been collected pre-treatment (T0) and 3 months after treatment (T1) and were additionally collected during subsequent aftercare visits, until the final assessment (T2). Primary outcome was the need for additional surgical peri-implantitis therapy during the aftercare programme, analysed via Kaplan–Meier analysis and Cox regression. Secondary outcomes involved clinical parameters, assessed using parametric and non-parametric tests.

Results

Forty-five patients (22 AB− group, 23 AB+ group) were included. The mean follow-up time between T1 and T2 was 35.9 months (SD = 21.0). 73.9% of the AB+ group and 50.0% of the AB− group did not receive additional surgical therapy (log-rank test, p = .110). The adjusted Cox regression model did not provide a significant result for antibiotics (β = .441, 95% CI = 0.159–1.220, p = .115). Univariable regression analysis highlighted the influence of baseline peri-implant pocket depth on the need for surgical treatment (β = 1.446, 95% CI = 1.035–2.020, p = .031).

Conclusions

Systemic amoxicillin and metronidazole administered during non-surgical peri-implantitis treatment do not seem to prevent the need for additional surgical therapy in the long term, during a structured aftercare programme.

目的:对一项为期 3 个月的研究进行回顾性长期随访,旨在评估使用辅助性全身抗生素进行非手术种植体周围炎治疗是否会影响对额外手术治疗的需求:对参加非手术种植体周围炎治疗后护理计划的患者进行分析,无论是否使用全身性阿莫西林和甲硝唑。此前已收集了治疗前(T0)和治疗后 3 个月(T1)的数据,并在随后的术后护理访问中收集了更多数据,直至最终评估(T2)。主要结果是在术后护理期间是否需要额外的外科种植体周围炎治疗,通过卡普兰-梅耶分析和考克斯回归进行分析。次要结果涉及临床参数,采用参数和非参数检验进行评估:共纳入45名患者(22名AB-组,23名AB+组)。从T1到T2的平均随访时间为35.9个月(SD = 21.0)。73.9%的AB+组患者和50.0%的AB-组患者没有接受额外的手术治疗(log-rank检验,P = .110)。调整后的 Cox 回归模型并未得出抗生素的显著结果(β = .441,95% CI = 0.159-1.220,p = .115)。单变量回归分析强调了基线种植窝洞深度对手术治疗需求的影响(β = 1.446,95% CI = 1.035-2.020,p = .031):结论:在非手术种植体周围炎治疗过程中使用全身性阿莫西林和甲硝唑似乎并不能防止在有组织的术后护理计划中长期需要额外的手术治疗。
{"title":"Do systemic amoxicillin and metronidazole during the non-surgical peri-implantitis treatment phase prevent the need for future surgical treatment? A retrospective long-term cohort study","authors":"Jarno Hakkers,&nbsp;Tine E. Vangsted,&nbsp;Arie Jan van Winkelhoff,&nbsp;Yvonne C. M. de Waal","doi":"10.1111/jcpe.14024","DOIUrl":"10.1111/jcpe.14024","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The aim of this retrospective long-term follow-up of a 3-month RCT was to assess whether non-surgical peri-implantitis treatment with adjunctive systemic antibiotics influenced the need for additional surgical treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Patients enrolled in an aftercare programme following non-surgical peri-implantitis treatment, with or without systemic amoxicillin and metronidazole, were analysed. Data had previously been collected pre-treatment (T<sub>0</sub>) and 3 months after treatment (T<sub>1</sub>) and were additionally collected during subsequent aftercare visits, until the final assessment (T<sub>2</sub>). Primary outcome was the need for additional surgical peri-implantitis therapy during the aftercare programme, analysed via Kaplan–Meier analysis and Cox regression. Secondary outcomes involved clinical parameters, assessed using parametric and non-parametric tests.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty-five patients (22 AB− group, 23 AB+ group) were included. The mean follow-up time between T<sub>1</sub> and T<sub>2</sub> was 35.9 months (SD = 21.0). 73.9% of the AB+ group and 50.0% of the AB− group did not receive additional surgical therapy (log-rank test, <i>p</i> = .110). The adjusted Cox regression model did not provide a significant result for antibiotics (<i>β</i> = .441, 95% CI = 0.159–1.220, <i>p</i> = .115). Univariable regression analysis highlighted the influence of baseline peri-implant pocket depth on the need for surgical treatment (<i>β</i> = 1.446, 95% CI = 1.035–2.020, <i>p</i> = .031).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Systemic amoxicillin and metronidazole administered during non-surgical peri-implantitis treatment do not seem to prevent the need for additional surgical therapy in the long term, during a structured aftercare programme.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15380,"journal":{"name":"Journal of Clinical Periodontology","volume":"51 8","pages":"997-1004"},"PeriodicalIF":5.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jcpe.14024","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141261083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Decision-making on systemic antibiotics in the management of periodontitis: A retrospective comparison of two concepts 牙周炎治疗中全身使用抗生素的决策:两种概念的回顾性比较。
IF 5.8 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-03 DOI: 10.1111/jcpe.14003
Patrizia C. Winkler, Leander Benz, Katrin Nickles, Hari C. Petsos, Peter Eickholz, Bettina Dannewitz

Aim

To retrospectively compare two approaches for the adjunctive use of systemic antibiotics in non-surgical periodontal therapy: one based on the detection of Aggregatibacter actinomycetemcomitans (Aa) and the other on age and severity of periodontitis (Age & PPD). We also assessed the additional benefit of antibiotics in reducing the need for further surgical therapy in each group.

Materials and Methods

Patients of the Department of Periodontology, Goethe University Frankfurt, Germany, were screened for microbiological testing between 2008 and 2018. Patients were categorized by their microbiological result (Aa+/−) and demographic/clinical data (Age & PPD+/−). Agreement on antibiotic indication was tested. The clinical evaluation focussed on teeth with probing pocket depths (PPDs) ≥ 6 mm.

Results

Analysis of 425 patients revealed 30% categorized as Age & PPD+ and 34% as Aa+. Sixty-three percent had consistent antibiotic recommendations (phi coefficient 0.14, p = .004). Patients in the Age & PPD+ group receiving antibiotics showed the most substantial reduction in the number of teeth with PPD ≥ 6 mm after non-surgical periodontal therapy.

Conclusions

Both strategies resulted in a significant clinical improvement compared with those without antibiotic treatment and restricted antibiotic use similarly, but targeted different patient groups. Younger individuals with severe periodontitis benefited most from antibiotics, reducing the need for additional surgeries. The study was registered in an international trial register (German Clinical Trial Register number DRKS00028768, registration date 27 April 2022, https://drks.de/search/en/trial/DRKS00028768).

目的:回顾性比较在非手术牙周治疗中辅助使用全身抗生素的两种方法:一种是基于放线菌(Aa)的检测,另一种是基于牙周炎的年龄和严重程度(年龄和 PPD)。我们还评估了抗生素在减少每组患者进一步手术治疗需求方面的额外益处:2008 年至 2018 年期间,德国法兰克福歌德大学牙周病学系的患者接受了微生物检测筛查。根据微生物检测结果(Aa+/-)和人口学/临床数据(年龄和 PPD+/-)对患者进行分类。对抗生素适应症的一致性进行了测试。临床评估的重点是探查袋深度(PPD)≥ 6 毫米的牙齿:对 425 名患者的分析显示,30% 的患者被归类为年龄和 PPD+,34% 的患者被归类为 Aa+。63%的患者得到了一致的抗生素建议(phi系数0.14,p = .004)。接受抗生素治疗的年龄和 PPD+ 组患者在接受非手术牙周治疗后,PPD ≥ 6 mm 的牙齿数量明显减少:结论:与未使用抗生素治疗的患者相比,两种策略都能显著改善临床症状,并且限制抗生素的使用,但针对的患者群体不同。年轻的重度牙周炎患者从抗生素中获益最多,从而减少了额外手术的需求。该研究已在国际试验注册中心注册(德国临床试验注册号 DRKS00028768,注册日期 2022 年 4 月 27 日,https://drks.de/search/en/trial/DRKS00028768)。
{"title":"Decision-making on systemic antibiotics in the management of periodontitis: A retrospective comparison of two concepts","authors":"Patrizia C. Winkler,&nbsp;Leander Benz,&nbsp;Katrin Nickles,&nbsp;Hari C. Petsos,&nbsp;Peter Eickholz,&nbsp;Bettina Dannewitz","doi":"10.1111/jcpe.14003","DOIUrl":"10.1111/jcpe.14003","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To retrospectively compare two approaches for the adjunctive use of systemic antibiotics in non-surgical periodontal therapy: one based on the detection of <i>Aggregatibacter actinomycetemcomitans</i> (Aa) and the other on age and severity of periodontitis (Age &amp; PPD). We also assessed the additional benefit of antibiotics in reducing the need for further surgical therapy in each group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Patients of the Department of Periodontology, Goethe University Frankfurt, Germany, were screened for microbiological testing between 2008 and 2018. Patients were categorized by their microbiological result (Aa+/−) and demographic/clinical data (Age &amp; PPD+/−). Agreement on antibiotic indication was tested. The clinical evaluation focussed on teeth with probing pocket depths (PPDs) ≥ 6 mm.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Analysis of 425 patients revealed 30% categorized as Age &amp; PPD+ and 34% as Aa+. Sixty-three percent had consistent antibiotic recommendations (phi coefficient 0.14, <i>p</i> = .004). Patients in the Age &amp; PPD+ group receiving antibiotics showed the most substantial reduction in the number of teeth with PPD ≥ 6 mm after non-surgical periodontal therapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Both strategies resulted in a significant clinical improvement compared with those without antibiotic treatment and restricted antibiotic use similarly, but targeted different patient groups. Younger individuals with severe periodontitis benefited most from antibiotics, reducing the need for additional surgeries. The study was registered in an international trial register (German Clinical Trial Register number DRKS00028768, registration date 27 April 2022, https://drks.de/search/en/trial/DRKS00028768).</p>\u0000 </section>\u0000 </div>","PeriodicalId":15380,"journal":{"name":"Journal of Clinical Periodontology","volume":"51 9","pages":"1122-1133"},"PeriodicalIF":5.8,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jcpe.14003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiographic outcomes of lateral sinus floor elevation at sites without perforations and sites with perforations managed with a resorbable membrane: A retrospective study 用可吸收膜处理无穿孔部位和有穿孔部位的侧窦底抬高的影像学结果:回顾性研究。
IF 5.8 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-03 DOI: 10.1111/jcpe.14026
Zhikang Wang, Yuchen Wang, Zhou Yu, Like Tang, Jing Zhang, Guoli Yang, Tingben Huang

Aim

To evaluate the radiographic outcomes of lateral sinus floor elevation with simultaneous implant placement at sites without sinus membrane perforation (SMP) and sites with SMP managed with a resorbable membrane.

Materials and Methods

One hundred and thirty-nine patients and 170 implants (56 perforation, 114 non-perforation) were included. Cone-beam computed tomography (CBCT) images were taken before surgery (T0), immediately after surgery (T1) and 6 months after surgery (T2). Post-operative augmentation parameters, including endo-sinus bone gain (ESBG) along the implant axis, mean new bone height (NBH) surrounding the implant and augmentation volume (AV), were measured at T1 and T2.

Results

At T1, there were no significant differences in ESBG, NBH and AV between the two groups. At T2, although ESBG did not significantly differ between the two groups, NBH (8.50 ± 1.99 mm vs. 9.99 ± 2.52 mm, p = .039) and AV (519.37 ± 258.38 mm3 vs. 700.99 ± 346.53 mm3, p < .001) were significantly lower in the perforation group. The shrinkage of graft material from T1 to T2, including ΔESBG (p = .002), ΔNBH (p < .001) and ΔAV (p < .001), was higher in the perforation group.

Conclusions

SMP during LSFE with simultaneous implant placement is associated with greater resorption of the grafted area at a 6-month follow-up.

目的:评估在无上颌窦膜穿孔(SMP)部位和用可吸收膜处理的有上颌窦膜穿孔部位同时植入种植体进行上颌窦底外侧抬高术的影像学效果:纳入 139 名患者和 170 个种植体(56 个穿孔,114 个未穿孔)。分别在术前(T0)、术后即刻(T1)和术后 6 个月(T2)拍摄锥形束计算机断层扫描(CBCT)图像。在 T1 和 T2 阶段测量了术后增量参数,包括沿种植体轴线的窦内骨增量 (ESBG)、种植体周围的平均新骨高度 (NBH) 和增量 (AV):结果:在 T1 阶段,两组的 ESBG、NBH 和 AV 均无明显差异。结果:T1时,两组间ESBG、NBH和AV无明显差异;T2时,两组间ESBG无明显差异,但NBH(8.50 ± 1.99 mm vs. 9.99 ± 2.52 mm,p = .039)和AV(519.37 ± 258.38 mm3 vs. 700.99 ± 346.53 mm3,p 结论:两组间ESBG、NBH和AV无明显差异:在 LSFE 期间进行 SMP 并同时植入种植体与 6 个月随访时移植区域的更大吸收有关。
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引用次数: 0
Reply to Letter to the Editor: Effect of periodontal therapy on glycaemic control in type 2 diabetes 回复致编辑的信:牙周治疗对 2 型糖尿病患者血糖控制的影响。
IF 5.8 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-30 DOI: 10.1111/jcpe.14007
Misuzu Sato, Sachiko Ono, Hideo Yasunaga, all authors
{"title":"Reply to Letter to the Editor: Effect of periodontal therapy on glycaemic control in type 2 diabetes","authors":"Misuzu Sato,&nbsp;Sachiko Ono,&nbsp;Hideo Yasunaga,&nbsp;all authors","doi":"10.1111/jcpe.14007","DOIUrl":"10.1111/jcpe.14007","url":null,"abstract":"","PeriodicalId":15380,"journal":{"name":"Journal of Clinical Periodontology","volume":"51 9","pages":"1255"},"PeriodicalIF":5.8,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to Letter to the Editor “Diabetes and periodontitis” 回应致编辑的信 "糖尿病与牙周炎"。
IF 5.8 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-30 DOI: 10.1111/jcpe.14006
Eduardo Montero, David Herrera, the authors
{"title":"Response to Letter to the Editor “Diabetes and periodontitis”","authors":"Eduardo Montero,&nbsp;David Herrera,&nbsp;the authors","doi":"10.1111/jcpe.14006","DOIUrl":"10.1111/jcpe.14006","url":null,"abstract":"","PeriodicalId":15380,"journal":{"name":"Journal of Clinical Periodontology","volume":"51 9","pages":"1254"},"PeriodicalIF":5.8,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diabetes and periodontitis 糖尿病与牙周炎
IF 5.8 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-30 DOI: 10.1111/jcpe.14004
Bryan S. Michalowicz, Bruce L. Pihlstrom, James S. Hodges
{"title":"Diabetes and periodontitis","authors":"Bryan S. Michalowicz,&nbsp;Bruce L. Pihlstrom,&nbsp;James S. Hodges","doi":"10.1111/jcpe.14004","DOIUrl":"10.1111/jcpe.14004","url":null,"abstract":"","PeriodicalId":15380,"journal":{"name":"Journal of Clinical Periodontology","volume":"51 9","pages":"1252-1253"},"PeriodicalIF":5.8,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Clinical Periodontology
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