Pub Date : 2023-06-03DOI: 10.9734/jocamr/2023/v22i2454
Oghenefego Michael Adheke, Nicholas Asiwe, P. O. Uahomo, Chidi Emmanuel Ezerioha, Lenton Igwangi Wariboko, Faustina Chiamaka Irozulike, Angela Ijeoma Opara
Background and Aim: Presently, medical students form a vital group of aspiring health professionals that are trained in order to assist in promoting healthcare worldwide. However, there is need to understand how these students derive motivation based on various determinants that enable them in choosing to study related disciplines in medical sciences – hence the aim of this present study. Materials and Methods: Using a qualitative, survey research design, this cross-sectional study comprising of two hundred (200) pre-medical and medical students (98 males and 102 females) between the ages of 16 to 25 years were randomly selected from the University of Port Harcourt and issued a semi-structured questionnaire containing two sections: socio-demographic variables and the determinants influencing career choice in medical sciences. Results: The majority of respondents in the age range of 16 – 19 years (accounting for a combined 88.0% of student population) did fill their study questionnaires. There were significant age and gender differences in some of the determinants such as parental and peer influence, prospects of travelling abroad to practice, and financial benefits. Conclusion: The study resolved that there was a need to educate these students to have the right motivation towards aspiring to study in the medical sciences.
{"title":"Assessment of Determinants for Choosing Medical Sciences as a Career Path amongst Medical Students of University of Port-Harcourt, Nigeria","authors":"Oghenefego Michael Adheke, Nicholas Asiwe, P. O. Uahomo, Chidi Emmanuel Ezerioha, Lenton Igwangi Wariboko, Faustina Chiamaka Irozulike, Angela Ijeoma Opara","doi":"10.9734/jocamr/2023/v22i2454","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v22i2454","url":null,"abstract":"Background and Aim: Presently, medical students form a vital group of aspiring health professionals that are trained in order to assist in promoting healthcare worldwide. However, there is need to understand how these students derive motivation based on various determinants that enable them in choosing to study related disciplines in medical sciences – hence the aim of this present study. \u0000Materials and Methods: Using a qualitative, survey research design, this cross-sectional study comprising of two hundred (200) pre-medical and medical students (98 males and 102 females) between the ages of 16 to 25 years were randomly selected from the University of Port Harcourt and issued a semi-structured questionnaire containing two sections: socio-demographic variables and the determinants influencing career choice in medical sciences. \u0000Results: The majority of respondents in the age range of 16 – 19 years (accounting for a combined 88.0% of student population) did fill their study questionnaires. There were significant age and gender differences in some of the determinants such as parental and peer influence, prospects of travelling abroad to practice, and financial benefits. \u0000Conclusion: The study resolved that there was a need to educate these students to have the right motivation towards aspiring to study in the medical sciences.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89601935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-03DOI: 10.9734/jocamr/2023/v22i2455
Ajirioghene E. Akpotu, S. Ghasi, Doris N. Ajibo, A. O. Ike, Amenotie Joy Akhator, J. Enya, Ijeoma Onyeleonu
Bioactive constituents are the active ingredients of herbal product such as Dryopteris dilataa that possess therapeutic efficacies in the treatment and management of several diseases. Thus, we evaluated different concentration of the free radical scavenging activity and phytochemical constituents of ethanol and sub-extracts of Dryopteris dilatata (Dd) leaves such as butane, hexane and benzene. Phytochemicals analysis was determined on the ethanol extract of Dryopteris dilatata sub-extracts using standard principles, also free radical scavenging capacity of the ethanol extract for Ferric reducing antioxidant power (FRAP), hydroxyl radical scavenging assay (OH), superoxide radical scavenging assay (SSRA), 2,2--Diphenyl-1-Picrylhydrazyl assay (DPPH), 2, 2'-azino-bis 3-ethylbenzthiazoline-6-sulphoric acid scavenging activity (ABTS) and thiobarbituric acid (TBA) assay (TBA) was done using standard protocols. Results of the phytochemical analysis revealed flavonoids and cardiac glycosides in all extracts, terpenoid, phytosterol, alkaloid, tannins and saponin constituents were present in ethanol, butane and hexane extracts and absent in benzene extract, phenols is present in only hexane extract but absent in all other extracts, glycerols is present in only benzene extracts while phlobotannin and carbohydrate are absent in all extracts. The plant ethanol extract revealed statistically significant at P<0.05 capacity for (FRAP), (OH), (SSRA), (DPPH), (ABTS), (TA). The study therefore suggest that the plant extract could lead to producing therapeutic agent in the treatment and management of several disorders that are attributed to reactive species and oxidative stress.
{"title":"Free Radical Scavenging Activity and Phytochemical Investigation of Ethanol Leaf Extract of Dryopteris dilatata","authors":"Ajirioghene E. Akpotu, S. Ghasi, Doris N. Ajibo, A. O. Ike, Amenotie Joy Akhator, J. Enya, Ijeoma Onyeleonu","doi":"10.9734/jocamr/2023/v22i2455","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v22i2455","url":null,"abstract":"Bioactive constituents are the active ingredients of herbal product such as Dryopteris dilataa that possess therapeutic efficacies in the treatment and management of several diseases. Thus, we evaluated different concentration of the free radical scavenging activity and phytochemical constituents of ethanol and sub-extracts of Dryopteris dilatata (Dd) leaves such as butane, hexane and benzene. Phytochemicals analysis was determined on the ethanol extract of Dryopteris dilatata sub-extracts using standard principles, also free radical scavenging capacity of the ethanol extract for Ferric reducing antioxidant power (FRAP), hydroxyl radical scavenging assay (OH), superoxide radical scavenging assay (SSRA), 2,2--Diphenyl-1-Picrylhydrazyl assay (DPPH), 2, 2'-azino-bis 3-ethylbenzthiazoline-6-sulphoric acid scavenging activity (ABTS) and thiobarbituric acid (TBA) assay (TBA) was done using standard protocols. Results of the phytochemical analysis revealed flavonoids and cardiac glycosides in all extracts, terpenoid, phytosterol, alkaloid, tannins and saponin constituents were present in ethanol, butane and hexane extracts and absent in benzene extract, phenols is present in only hexane extract but absent in all other extracts, glycerols is present in only benzene extracts while phlobotannin and carbohydrate are absent in all extracts. The plant ethanol extract revealed statistically significant at P<0.05 capacity for (FRAP), (OH), (SSRA), (DPPH), (ABTS), (TA). The study therefore suggest that the plant extract could lead to producing therapeutic agent in the treatment and management of several disorders that are attributed to reactive species and oxidative stress.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90533479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-31DOI: 10.9734/jocamr/2023/v22i2453
Rika Aswita
Clean and healthy living behavior is essentially the basis for preventing humans from various diseases. Health is everyone's dream and need. The principle of clean and healthy living behavior (PHBS) is one of the cornerstones and health development programs in Indonesia. The purpose of this study is to analyze the influence of health promotion strategies (advocacy, atmosphere building, and community empowerment movements) on the level of Clean and Healthy Living Behavior (PHBS) in Household Settings in Subulussalam City Subdistrict. The population of this study was all heads of families in Penanggalan Kota Subulussalam District. The sample of this study is part of the heads of families from the number of heads of families in Penanggalan District, which is 14,394 households. Measurement of independent variables using the Likert Scale, with some conditions. The results showed that PHBS most respondents (56 people, 56%) were in the Healthy II category, followed by Healthy IV as many as 25 respondents (25%), healthy III as many as 14 respondents (14%), and healthy I as many as 5 respondents (5%). This condition shows that most respondents have not met the healthy category standards set by the Ministry of Health, namely PHBS healthy category IV.
{"title":"The Effect of Health Promotion Strategies on the Level of Clean and Healthy Living Behavior (PHBS) in Household Settings in Penanggalan Sub-district of Subulussalam","authors":"Rika Aswita","doi":"10.9734/jocamr/2023/v22i2453","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v22i2453","url":null,"abstract":"Clean and healthy living behavior is essentially the basis for preventing humans from various diseases. Health is everyone's dream and need. The principle of clean and healthy living behavior (PHBS) is one of the cornerstones and health development programs in Indonesia. The purpose of this study is to analyze the influence of health promotion strategies (advocacy, atmosphere building, and community empowerment movements) on the level of Clean and Healthy Living Behavior (PHBS) in Household Settings in Subulussalam City Subdistrict. The population of this study was all heads of families in Penanggalan Kota Subulussalam District. The sample of this study is part of the heads of families from the number of heads of families in Penanggalan District, which is 14,394 households. Measurement of independent variables using the Likert Scale, with some conditions. The results showed that PHBS most respondents (56 people, 56%) were in the Healthy II category, followed by Healthy IV as many as 25 respondents (25%), healthy III as many as 14 respondents (14%), and healthy I as many as 5 respondents (5%). This condition shows that most respondents have not met the healthy category standards set by the Ministry of Health, namely PHBS healthy category IV.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87678910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-29DOI: 10.9734/jocamr/2023/v22i1451
Yusliana
The increasing trend of health care costs has prompted the government to seek financing alternatives that can streamline funds without reducing the quality of services. One such system is the implementation of the commitment-based capitation consequence where the puskesmas is paid based on the number of registered participants who are responsible for its effectiveness monitoring by looking at the tendency of contact numbers (≥1500/00), prolanis ratio (≥50%), and non-specialist case referral ratio (<0.5%), so it is expected that moral hazard from the supply side can be prevented or minimized. This study aims to determine the factors associated with the implementation of Capitation Based on Service Commitment. This research was conducted in Propinsi Aceh area with Puskesmas as analysis unit, with sequential model mixed method (quan à QUAL), qualitative data was taken by indeph interview method to key informant related to validate data which can not be validated by quantitative method. The results of two year implementation significantly increased the average contact rate in 2020 by 192.6 0/00 (target ≥150 0/00), and the average prolanis ratio of 44.9% (≥50%), and lowering the average non-specialist case referral ratio to 0.3% (target <5%). From multivariate analysis, variables modeling related to achievement of service commitment indicator were capitation value, human resources (adequacy of doctor, nurse, midwife, pharmacy) are significant influence dominanly to achievement indicator of service commitment (p value <0.05). mplementation of capitation compensation is positive enough to give an effect for all puskesmas efforts to achieve the indicator of service commitment, on the other side of the indication of moral hazard, so monitoring and evaluation is needed to create the quality service.
{"title":"Factors Related to the Achievement of Service Commitment-based Capitation Indicators at Community Health Centers in Aceh Province","authors":"Yusliana","doi":"10.9734/jocamr/2023/v22i1451","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v22i1451","url":null,"abstract":"The increasing trend of health care costs has prompted the government to seek financing alternatives that can streamline funds without reducing the quality of services. One such system is the implementation of the commitment-based capitation consequence where the puskesmas is paid based on the number of registered participants who are responsible for its effectiveness monitoring by looking at the tendency of contact numbers (≥1500/00), prolanis ratio (≥50%), and non-specialist case referral ratio (<0.5%), so it is expected that moral hazard from the supply side can be prevented or minimized. This study aims to determine the factors associated with the implementation of Capitation Based on Service Commitment. \u0000This research was conducted in Propinsi Aceh area with Puskesmas as analysis unit, with sequential model mixed method (quan à QUAL), qualitative data was taken by indeph interview method to key informant related to validate data which can not be validated by quantitative method. \u0000The results of two year implementation significantly increased the average contact rate in 2020 by 192.6 0/00 (target ≥150 0/00), and the average prolanis ratio of 44.9% (≥50%), and lowering the average non-specialist case referral ratio to 0.3% (target <5%). From multivariate analysis, variables modeling related to achievement of service commitment indicator were capitation value, human resources (adequacy of doctor, nurse, midwife, pharmacy) are significant influence dominanly to achievement indicator of service commitment (p value <0.05). \u0000mplementation of capitation compensation is positive enough to give an effect for all puskesmas efforts to achieve the indicator of service commitment, on the other side of the indication of moral hazard, so monitoring and evaluation is needed to create the quality service.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84415464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-29DOI: 10.9734/jocamr/2023/v22i1450
Lisa Rahmiati
One of the intervention programs to improve the nutrition of pregnant women is supplementary feeding (PMT). The nutritional problem of pregnant women that is often found in the community is the lack of intake of macronutrients and micronutrients. The method used in this study was a sequential mixed method with a sequential explanatory design. The results of this study were the percentage of consumption of MT biscuits by 5 pregnant women with KEK who consumed ≥ 80%. The perception of pregnant women about the severity of chronic energy deficiency (CED) health problems with an arm circumference of less than 23.5 cm is not a health problem that is dangerous for pregnant women. Understanding of PMT biscuit consumption instructions from officers is still lacking. There is no social support in the implementation of PMT for pregnant women from KEK. The availability of PMT for pregnant women from KEK has not been fulfilled in accordance with applicable regulations.
{"title":"Consumption Compliance Supplementary Food Biscuits for Pregnant Women in Banda Aceh, Indonesia","authors":"Lisa Rahmiati","doi":"10.9734/jocamr/2023/v22i1450","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v22i1450","url":null,"abstract":"One of the intervention programs to improve the nutrition of pregnant women is supplementary feeding (PMT). The nutritional problem of pregnant women that is often found in the community is the lack of intake of macronutrients and micronutrients. The method used in this study was a sequential mixed method with a sequential explanatory design. The results of this study were the percentage of consumption of MT biscuits by 5 pregnant women with KEK who consumed ≥ 80%. The perception of pregnant women about the severity of chronic energy deficiency (CED) health problems with an arm circumference of less than 23.5 cm is not a health problem that is dangerous for pregnant women. Understanding of PMT biscuit consumption instructions from officers is still lacking. There is no social support in the implementation of PMT for pregnant women from KEK. The availability of PMT for pregnant women from KEK has not been fulfilled in accordance with applicable regulations.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91026028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-29DOI: 10.9734/jocamr/2023/v22i2452
Rinaldi
Community empowerment is very important to do with the aim that people become independent, in the sense that they have the potential to be able to solve the problems they face, and are able to meet their needs by not depending their lives on outside assistance, both government and non-government organizations. Midwives in the Village with individual characteristics are mostly aged less than 35 years, married status, Diploma-III education, with a working period of more than 6 years and most have become civil servants. The knowledge of village midwives about the development of Desa Siaga is 91.5% good, but the attitudes of village midwives towards the community empowerment process in developing Desa Siaga are more unsupportive, namely 57.3% and those who support 42.7%. Meanwhile, midwives in villages who have high work motivation as facilitators for Desa Siaga development are 58.5% and those who have low motivation are 41.5%. The level of activeness of the Village Midwife in social organizations, such as TP activities. PKK in the village, TP. PKK. Only 57.3% of midwives in the village can carry out the community empowerment process well, while 42.7% are still considered unfavorable. Of the 6 (six) stages of the empowerment process, only 70.7% help determine priorities. in sub-districts, and activities of religious organizations, is still very low at 3.7%.
{"title":"Efforts to Improve the Capacity of Midwife in the Village to Conduct the Community Empowerment Process Towards an Active Alert in Pidie Jaya","authors":"Rinaldi","doi":"10.9734/jocamr/2023/v22i2452","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v22i2452","url":null,"abstract":"Community empowerment is very important to do with the aim that people become independent, in the sense that they have the potential to be able to solve the problems they face, and are able to meet their needs by not depending their lives on outside assistance, both government and non-government organizations. Midwives in the Village with individual characteristics are mostly aged less than 35 years, married status, Diploma-III education, with a working period of more than 6 years and most have become civil servants. The knowledge of village midwives about the development of Desa Siaga is 91.5% good, but the attitudes of village midwives towards the community empowerment process in developing Desa Siaga are more unsupportive, namely 57.3% and those who support 42.7%. Meanwhile, midwives in villages who have high work motivation as facilitators for Desa Siaga development are 58.5% and those who have low motivation are 41.5%. The level of activeness of the Village Midwife in social organizations, such as TP activities. PKK in the village, TP. PKK. Only 57.3% of midwives in the village can carry out the community empowerment process well, while 42.7% are still considered unfavorable. Of the 6 (six) stages of the empowerment process, only 70.7% help determine priorities. in sub-districts, and activities of religious organizations, is still very low at 3.7%.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87113383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-27DOI: 10.9734/jocamr/2023/v22i1449
C. Wekhe, Vivian Ndidi Akagbue, M. Amadi
Background: Computed tomography urography (CTU) is the current radiological imaging modality for the evaluation of the kidneys, ureters and urinary bladder pathologies. CTU has largely replaced intravenous urography in centers that has computed tomogram machines. Objectives: The aim of this study is to identify the common location of urolithiasis in the urinary tract and correlate it with age, sex, stone size and Hounsfield unit (HU) using CT scan in the Radiology department of Rivers State University Teaching Hospital. Methods: A retrospective study with descriptive study design was employed. A total of 140 patient’s data were used. A P-value below 0.05 was considered statistically significant. Results: One-hundred and forty patients were studied over a 24 months period. The median age was 43.50 years. The prevalence of stones (n=47, 33.6%) and age range with the highest prevalence is 41-50 years. The male: female was 1.8:1. Renal stones are commonly found in the inferior pole. Vesicoureteric junction stones were more prevalent in females. There was significant association between age and sex. (P=0.005). Conclusion: Urolithiasis is commonly seen in males. The location of calculi in the urinary tract is in the kidney, pelviureteric junction (PUJ), vesicoureteric junction (VUJ), ureters and the urinary bladder in a downhill order correspondingly. The inferior pole is the most prevalent site for renal stones and VUJ stones are more frequent in females while other locations are seen more in males. Interestingly, age and sex showed significant association.
背景:计算机断层尿路造影(CTU)是目前评估肾脏、输尿管和膀胱病变的放射成像方式。CTU已经在很大程度上取代了有计算机断层扫描仪的中心的静脉尿路造影。目的:本研究的目的是通过CT扫描确定尿路中尿石症的常见部位，并将其与年龄、性别、结石大小和Hounsfield unit (HU)联系起来。方法:采用描述性研究设计的回顾性研究。总共使用了140名患者的数据。p值小于0.05认为有统计学意义。结果:140例患者在24个月的时间内被研究。中位年龄为43.50岁。结石患病率(n=47, 33.6%)，患病率最高的年龄段为41-50岁。男女比例为1.8:1。肾结石常见于肾下极。膀胱输尿管交界处结石多见于女性。年龄和性别之间存在显著关联。(P = 0.005)。结论:尿石症常见于男性。尿路结石的位置依次为肾脏、肾盂输尿管连接处(PUJ)、膀胱输尿管连接处(VUJ)、输尿管和膀胱。下极是肾结石最常见的部位，女性肾结石多见于VUJ，而男性肾结石多见于其他部位。有趣的是，年龄和性别表现出显著的相关性。
{"title":"Demographic, Clinical and Radiological Findings among Patients with CTU Detected Urolithiasis in a Tertiary Hospital","authors":"C. Wekhe, Vivian Ndidi Akagbue, M. Amadi","doi":"10.9734/jocamr/2023/v22i1449","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v22i1449","url":null,"abstract":"Background: Computed tomography urography (CTU) is the current radiological imaging modality for the evaluation of the kidneys, ureters and urinary bladder pathologies. CTU has largely replaced intravenous urography in centers that has computed tomogram machines. \u0000Objectives: The aim of this study is to identify the common location of urolithiasis in the urinary tract and correlate it with age, sex, stone size and Hounsfield unit (HU) using CT scan in the Radiology department of Rivers State University Teaching Hospital. \u0000Methods: A retrospective study with descriptive study design was employed. A total of 140 patient’s data were used. A P-value below 0.05 was considered statistically significant. \u0000Results: One-hundred and forty patients were studied over a 24 months period. The median age was 43.50 years. The prevalence of stones (n=47, 33.6%) and age range with the highest prevalence is 41-50 years. The male: female was 1.8:1. Renal stones are commonly found in the inferior pole. Vesicoureteric junction stones were more prevalent in females. There was significant association between age and sex. (P=0.005). \u0000Conclusion: Urolithiasis is commonly seen in males. The location of calculi in the urinary tract is in the kidney, pelviureteric junction (PUJ), vesicoureteric junction (VUJ), ureters and the urinary bladder in a downhill order correspondingly. The inferior pole is the most prevalent site for renal stones and VUJ stones are more frequent in females while other locations are seen more in males. Interestingly, age and sex showed significant association.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82898347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-27DOI: 10.9734/jocamr/2023/v22i1448
Shania Mathew, J. D. Souza
Transgenders have always caught my attention. Be it at the signal where they are seen begging or in a moving bus where everyone shuns away from sitting near them. My initial fears about them turned to curiosity as to who they are. Are they normal? No one around me was able to give me any answer. I was apprehensive to talk to anyone too as I was always told they may harm me. But I made it a point to attend meetings that transgenders attended, squeezed myself into talking to them and getting acquainted with the group, and to my surprise I found out they were such a welcoming group. I gelled with them faster than I thought and today I am glad they are a part of my journey. As I explored their lives, the one thing I realized was that even healthcare members are not fully aware of transgenders, rather, they have too many misconceptions. And so, the need of the hour is that healthcare professionals should be trained on transgenders especially when statistics show that as per the 2011 census, there are around 4.8 million transgenders in India. The number is way more than this.
{"title":"Transgenders: The Neglected Group in Health Care","authors":"Shania Mathew, J. D. Souza","doi":"10.9734/jocamr/2023/v22i1448","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v22i1448","url":null,"abstract":"Transgenders have always caught my attention. Be it at the signal where they are seen begging or in a moving bus where everyone shuns away from sitting near them. My initial fears about them turned to curiosity as to who they are. Are they normal? No one around me was able to give me any answer. I was apprehensive to talk to anyone too as I was always told they may harm me. But I made it a point to attend meetings that transgenders attended, squeezed myself into talking to them and getting acquainted with the group, and to my surprise I found out they were such a welcoming group. I gelled with them faster than I thought and today I am glad they are a part of my journey. As I explored their lives, the one thing I realized was that even healthcare members are not fully aware of transgenders, rather, they have too many misconceptions. And so, the need of the hour is that healthcare professionals should be trained on transgenders especially when statistics show that as per the 2011 census, there are around 4.8 million transgenders in India. The number is way more than this.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82111654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-23DOI: 10.9734/jocamr/2023/v22i1447
B. Faleye, F. Bamisaye, T. Fatoki
Heliotropium indicum (Indian heliotrope) belongs to family Boraginaceae, which has wide ethnopharmacological applications such as antiulcer, antirheumatism and anti-cholera. The aim of this study was to characterize the phytochemicals in H. indicum ethanolic leaves extract using Gas chromatography-mass spectrometry (GC-MS), and computationally assessed its pharmacokinetics profiles, molecular targets and infer overall medicinal application. The results showed twenty-nine (29) identified constituents of H. indicum in its ethanolic leaves extract from GC-MS, many of which are poorly soluble and have low gastrointestinal absorption (GIA). However, some of them are soluble with high GIA and could permeate blood brain barrier (BBB). The results showed that (+)-Isomenthol, and Ergost-22-en-3-ol are the two most active constituents of ethanolic leaves extract of H. indicum; targeting androgen receptor (AR) and transient receptor potential cation channel subfamily M member 8 (TRPM8), which have implication in prostate cancer. Thus, H. indicum plant extract is a potential anti-PCa medicinal plants. However, there is need for in vivo and in vitro studies to validate these results, hence promoting these active compounds optimization and clinical evaluations in H. indicum.
{"title":"GC-MS Characterization and Computational Assessment of Phytochemicals in Heliotropium indicum Ethanolic Leaves Extract","authors":"B. Faleye, F. Bamisaye, T. Fatoki","doi":"10.9734/jocamr/2023/v22i1447","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v22i1447","url":null,"abstract":"Heliotropium indicum (Indian heliotrope) belongs to family Boraginaceae, which has wide ethnopharmacological applications such as antiulcer, antirheumatism and anti-cholera. The aim of this study was to characterize the phytochemicals in H. indicum ethanolic leaves extract using Gas chromatography-mass spectrometry (GC-MS), and computationally assessed its pharmacokinetics profiles, molecular targets and infer overall medicinal application. The results showed twenty-nine (29) identified constituents of H. indicum in its ethanolic leaves extract from GC-MS, many of which are poorly soluble and have low gastrointestinal absorption (GIA). However, some of them are soluble with high GIA and could permeate blood brain barrier (BBB). The results showed that (+)-Isomenthol, and Ergost-22-en-3-ol are the two most active constituents of ethanolic leaves extract of H. indicum; targeting androgen receptor (AR) and transient receptor potential cation channel subfamily M member 8 (TRPM8), which have implication in prostate cancer. Thus, H. indicum plant extract is a potential anti-PCa medicinal plants. However, there is need for in vivo and in vitro studies to validate these results, hence promoting these active compounds optimization and clinical evaluations in H. indicum.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79991959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-20DOI: 10.9734/jocamr/2023/v21i4446
Oluwatosin T. Ayodele, O. Olaoluwa, O. Aiyelaagbe, F. Guido, O. Ogbole, Toluwanimi E. Akinleye, A. Adeniji
Introduction: The Increase in cancer deaths has raised concerns among scientists to research on prospective anticancer agents. Lannea egregia was selected for this research because it has been identified to have ethnobotanical claims in relation to the cure of cancer in South-West Nigeria. Aims: To analyze the chemical constituents and determine the anticancer properties of the essential oils obtained from Lannea egregia Engl. & K. Krause Leaf, twig and stem-bark. Study Design: This study was designed to assay the chemical constituents of Lannea egregia and based on the ethnobotanical claims, the anticancer activities of this plant was studied. Place and Duration of Study: Department of Chemistry, Dipartmento di Farmacia, Via Bonanno 6, Universita di Pisa and University of Ibadan and Department of Virology, University of Ibadan, Ibadan, Nigeria. July 2018- April 2021. Methodology: Essential oils (EOs) from leaf, twig and stem-bark of Lannea egregia were extracted by hydro-distillation. Chemical compositions were characterized using Gas Chromatography–Mass Spectrometry (GC–MS). Cytotoxicity screenings of EOs were determined on human rhabdomyosarcoma (RD) and breast adenocarcinoma (MCF-7), using MTT [3-(4,5 dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] cell viability assay. Results: Leaf, twig and stem-bark EOs gave good yields of 0.12%, 0.43% and 0.33%, respectively. Fifty-five, thirty-three and thirty-eight compounds were identified in leaf, twig and stem-bark EOs, accounting for 99.1%, 97.8% and 95.8% of them. Most abundant compound in leaf, stem-bark and twig EOs was β-caryophellene (28.2, 23.4 and 13.2%, respectively). Leaf EO displayed strong cytotoxicity against RD and MCF-7, with 50% cytotoxicity (CC50) of 1.69 and 15.81µg/ml, respectively. Twig EO exhibited good selectivity with selectivity index of 24.8 and 10.8 for RD and MCF-7, respectively. Conclusion: Results showed that EOs have good anticancer properties.
{"title":"Biochemical Constituents and Anticancer Activities of the Essential Oils of Lannea egregia Engl. & K. Krause","authors":"Oluwatosin T. Ayodele, O. Olaoluwa, O. Aiyelaagbe, F. Guido, O. Ogbole, Toluwanimi E. Akinleye, A. Adeniji","doi":"10.9734/jocamr/2023/v21i4446","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v21i4446","url":null,"abstract":"Introduction: The Increase in cancer deaths has raised concerns among scientists to research on prospective anticancer agents. Lannea egregia was selected for this research because it has been identified to have ethnobotanical claims in relation to the cure of cancer in South-West Nigeria. \u0000Aims: To analyze the chemical constituents and determine the anticancer properties of the essential oils obtained from Lannea egregia Engl. & K. Krause Leaf, twig and stem-bark. \u0000Study Design: This study was designed to assay the chemical constituents of Lannea egregia and based on the ethnobotanical claims, the anticancer activities of this plant was studied. \u0000Place and Duration of Study: Department of Chemistry, Dipartmento di Farmacia, Via Bonanno 6, Universita di Pisa and University of Ibadan and Department of Virology, University of Ibadan, Ibadan, Nigeria. July 2018- April 2021. \u0000Methodology: Essential oils (EOs) from leaf, twig and stem-bark of Lannea egregia were extracted by hydro-distillation. Chemical compositions were characterized using Gas Chromatography–Mass Spectrometry (GC–MS). Cytotoxicity screenings of EOs were determined on human rhabdomyosarcoma (RD) and breast adenocarcinoma (MCF-7), using MTT [3-(4,5 dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] cell viability assay. \u0000Results: Leaf, twig and stem-bark EOs gave good yields of 0.12%, 0.43% and 0.33%, respectively. \u0000Fifty-five, thirty-three and thirty-eight compounds were identified in leaf, twig and stem-bark EOs, accounting for 99.1%, 97.8% and 95.8% of them. Most abundant compound in leaf, stem-bark and twig EOs was β-caryophellene (28.2, 23.4 and 13.2%, respectively). \u0000Leaf EO displayed strong cytotoxicity against RD and MCF-7, with 50% cytotoxicity (CC50) of 1.69 and 15.81µg/ml, respectively. Twig EO exhibited good selectivity with selectivity index of 24.8 and 10.8 for RD and MCF-7, respectively. \u0000Conclusion: Results showed that EOs have good anticancer properties.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"22 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72631562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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