Pub Date : 2023-08-10DOI: 10.9734/jocamr/2023/v23i4486
J. E. Judith, Oloye Temidayo Simisola, Ekere E. Kokonne, A. J. Isaac, Rashid A. Abdullahi, O. Olubunmi, Ndiana-Abasi Sunday, I. C. Yetunde, Emeje O. Martins
Aims: With a population of about 222 million, which is expected to rise to 377 million making Nigeria the 3rd largest country in the world by 2050, a well-planned family will improve the quality of life of mother and child. Methodology: A non-probability online survey was conducted (October 2021 and November 2021), recruiting 1113 participants across Nigeria. Socio-demographic data and information on contraceptives were obtained, and Pearson’s chi-squared test of independence at a 95% confidence interval (CI) was computed using R 4.2.1. Results: Significant associations (P < .001) were found between age, marital status, education, and profession of respondents. About 44.65% were 15-29 years, while 41.2% were 30-34 years. No significant association was observed between the age group, gender, and the need for population control. Females (50.04%), 15-29 years old (66.48%) are more likely to approve of the need for population control. Likewise, females (22.01%), with tertiary education (18.78%) are well-informed about contraceptive use (P < .001). Only 19.38% (n = 184; P < .001) of participants used herbal contraceptives, in the form of liquid mixtures (55.98%), teas (17.93%), pills (12.50%), and powders (10.87%), with 26.63% > 7.61% > 6.52% > 5.98% = 5.98% = 5.98% > 4.89% > 3.80% who took Moringa, Alligator Pepper, Neem Plant, Castor Beans, African Star apple Momordica, Rosary Pea, and Horse-eye Bean respectively as contraceptives. Aged parents (32.07%), friends (31.52%), doctors (15.76%), herbalists (5.98%), pharmacists (5.43%), and nurses (3.80%) played a significant (P < .001) role in recommending these herbs. Furthermore, 76.37% recommended the development of indigenous herbal contraceptives in Nigeria, while 23.63% did not. Conclusion: Although participants have expressed a preference for herbal contraceptives, knowledge of them is lacking, which calls for more awareness campaigns and policy formulations for their promotion, development, and adoption in Nigeria.
{"title":"Knowledge, Attitude, and Perception of Nigerians Towards Herbal Contraception: A Questionnaire- Based Study","authors":"J. E. Judith, Oloye Temidayo Simisola, Ekere E. Kokonne, A. J. Isaac, Rashid A. Abdullahi, O. Olubunmi, Ndiana-Abasi Sunday, I. C. Yetunde, Emeje O. Martins","doi":"10.9734/jocamr/2023/v23i4486","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v23i4486","url":null,"abstract":"Aims: With a population of about 222 million, which is expected to rise to 377 million making Nigeria the 3rd largest country in the world by 2050, a well-planned family will improve the quality of life of mother and child. \u0000Methodology: A non-probability online survey was conducted (October 2021 and November 2021), recruiting 1113 participants across Nigeria. Socio-demographic data and information on contraceptives were obtained, and Pearson’s chi-squared test of independence at a 95% confidence interval (CI) was computed using R 4.2.1. \u0000Results: Significant associations (P < .001) were found between age, marital status, education, and profession of respondents. About 44.65% were 15-29 years, while 41.2% were 30-34 years. No significant association was observed between the age group, gender, and the need for population control. Females (50.04%), 15-29 years old (66.48%) are more likely to approve of the need for population control. Likewise, females (22.01%), with tertiary education (18.78%) are well-informed about contraceptive use (P < .001). Only 19.38% (n = 184; P < .001) of participants used herbal contraceptives, in the form of liquid mixtures (55.98%), teas (17.93%), pills (12.50%), and powders (10.87%), with 26.63% > 7.61% > 6.52% > 5.98% = 5.98% = 5.98% > 4.89% > 3.80% who took Moringa, Alligator Pepper, Neem Plant, Castor Beans, African Star apple Momordica, Rosary Pea, and Horse-eye Bean respectively as contraceptives. Aged parents (32.07%), friends (31.52%), doctors (15.76%), herbalists (5.98%), pharmacists (5.43%), and nurses (3.80%) played a significant (P < .001) role in recommending these herbs. Furthermore, 76.37% recommended the development of indigenous herbal contraceptives in Nigeria, while 23.63% did not. \u0000Conclusion: Although participants have expressed a preference for herbal contraceptives, knowledge of them is lacking, which calls for more awareness campaigns and policy formulations for their promotion, development, and adoption in Nigeria.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78035468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-09DOI: 10.9734/jocamr/2023/v23i4485
Parul Gupta, N. Jain, S. K. Meena
Background: Parkinson's disease (PD) is a common neurodegenerative disorder affecting the elderly population and can lead to impaired balance, reaction time, and overall quality of life (QoL). Occupational therapy interventions have shown promise in managing the motor and non-motor symptoms of PD. This systematic review aims to evaluate the effectiveness of occupational therapy intervention on balance and reaction time to enhance the quality of life in patients with Parkinson's disease. Methods: A comprehensive search was conducted on various electronic databases, including PubMed, Google Scholar, and ResearchGate. Studies published between 2010 and 2022 were included in the review. Inclusion criteria were set for age, clinical diagnosis of Parkinson's disease, MoCA score, and cooperation for participation. Studies that did not meet the inclusion criteria or reported other interventions were excluded. Data from selected studies were analyzed for relevance, appropriateness, clarity, and methodology. Results: Out of the initial 250 potentially relevant articles, 200 were identified as duplicates and removed. Another 25 studies did not meet the inclusion criteria, and 15 studies did not provide sufficient information on the interventions. Eventually, 10 studies were included in this systematic review. All the studies were qualitative in nature and were published between 2010 and 2023. Conclusion: Occupational therapy interventions have shown promising results in enhancing balance, reaction time, and quality of life in patients with Parkinson's disease. The review emphasizes the importance of goal-oriented occupational therapy programs to improve the overall well-being of patients with PD. Further research in this area is warranted to strengthen the evidence and guide clinical practice for better management of Parkinson's disease.
{"title":"Enhancing Quality of Life in Parkinson’s Disease: A Systematic Review of Occupational Therapy Interventions on Balance and Reaction Time","authors":"Parul Gupta, N. Jain, S. K. Meena","doi":"10.9734/jocamr/2023/v23i4485","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v23i4485","url":null,"abstract":"Background: Parkinson's disease (PD) is a common neurodegenerative disorder affecting the elderly population and can lead to impaired balance, reaction time, and overall quality of life (QoL). Occupational therapy interventions have shown promise in managing the motor and non-motor symptoms of PD. This systematic review aims to evaluate the effectiveness of occupational therapy intervention on balance and reaction time to enhance the quality of life in patients with Parkinson's disease. \u0000Methods: A comprehensive search was conducted on various electronic databases, including PubMed, Google Scholar, and ResearchGate. Studies published between 2010 and 2022 were included in the review. Inclusion criteria were set for age, clinical diagnosis of Parkinson's disease, MoCA score, and cooperation for participation. Studies that did not meet the inclusion criteria or reported other interventions were excluded. Data from selected studies were analyzed for relevance, appropriateness, clarity, and methodology. \u0000Results: Out of the initial 250 potentially relevant articles, 200 were identified as duplicates and removed. Another 25 studies did not meet the inclusion criteria, and 15 studies did not provide sufficient information on the interventions. Eventually, 10 studies were included in this systematic review. All the studies were qualitative in nature and were published between 2010 and 2023. \u0000Conclusion: Occupational therapy interventions have shown promising results in enhancing balance, reaction time, and quality of life in patients with Parkinson's disease. The review emphasizes the importance of goal-oriented occupational therapy programs to improve the overall well-being of patients with PD. Further research in this area is warranted to strengthen the evidence and guide clinical practice for better management of Parkinson's disease.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81636041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-09DOI: 10.9734/jocamr/2023/v23i4484
Enyi, Ikpechi Ovundah, Joshua Charles Isirima
Background: Bordetella pertussis is the causative organism of an acute human respiratory tract disease known as pertussis – an endemic disease globally with reported cases in both developing and developed countries. This study evaluated the hypo-lipidaemic and histological effects of the crab specie Cardisoma guanhumi extracts on bordetela pertussis infected Swiss mice. Methods: One hundred and twenty-two (122) animals were divided into five groups in the study. Groups 1 and 2 were the normal and negative controls respectively, while groups 3 and 4 received (300mg/kg and 600mg/kg) of the extract and group 5 received 4000mg/70kg (57.14 mg/kg) of erythromycin. Blood and kidney samples were collected on days 0, 6, 12 and 18for lipid profile analysis and kidney histological examination. Results: The result shows that Animals exposed to B. pertussis inoculum dose (5.0x105cfu/ml) without treatment caused a decrease in the plasma level of high density lipo-protein cholesterol (HDL) and an increase in the plasma levels of total cholesterol, triglycerides and low density lipo-protein cholesterol (LDL). However, treatment with Cardisoma guanhumi extract reversed the observed effect thereby producing a gradual increase in HDL levels and decrease in triglycerides, cholesterol and LDL levels with no adverse effect on the kidney histology. Conclusion: The study reveals significant lipid profile alterations caused by B. pertussis infection in Swiss mice, highlights the potential lipid-lowering effects of Cardisoma guanhumi extract, and indicates the absence of apparent kidney damage from the infection.
{"title":"Cardisoma guanhumi as a Therapeutic Candidate: Assessing Hypo-lipidemic and Histological Effects in Bordetella pertussis Infected Swiss Mice","authors":"Enyi, Ikpechi Ovundah, Joshua Charles Isirima","doi":"10.9734/jocamr/2023/v23i4484","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v23i4484","url":null,"abstract":"Background: Bordetella pertussis is the causative organism of an acute human respiratory tract disease known as pertussis – an endemic disease globally with reported cases in both developing and developed countries. This study evaluated the hypo-lipidaemic and histological effects of the crab specie Cardisoma guanhumi extracts on bordetela pertussis infected Swiss mice. \u0000Methods: One hundred and twenty-two (122) animals were divided into five groups in the study. Groups 1 and 2 were the normal and negative controls respectively, while groups 3 and 4 received (300mg/kg and 600mg/kg) of the extract and group 5 received 4000mg/70kg (57.14 mg/kg) of erythromycin. Blood and kidney samples were collected on days 0, 6, 12 and 18for lipid profile analysis and kidney histological examination. \u0000Results: The result shows that Animals exposed to B. pertussis inoculum dose (5.0x105cfu/ml) without treatment caused a decrease in the plasma level of high density lipo-protein cholesterol (HDL) and an increase in the plasma levels of total cholesterol, triglycerides and low density lipo-protein cholesterol (LDL). However, treatment with Cardisoma guanhumi extract reversed the observed effect thereby producing a gradual increase in HDL levels and decrease in triglycerides, cholesterol and LDL levels with no adverse effect on the kidney histology. \u0000Conclusion: The study reveals significant lipid profile alterations caused by B. pertussis infection in Swiss mice, highlights the potential lipid-lowering effects of Cardisoma guanhumi extract, and indicates the absence of apparent kidney damage from the infection.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73390417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-08DOI: 10.9734/jocamr/2023/v23i4483
R. Umoh, I. Johnny, N. Andy, Anwanabasi E. Udoh, Trust E. Ekpo, Gabriel U. Ashibeshi
Mussaenda philippica Linn. belongs to the sub-family Ixoroideae which belongs to the family Rubiaceae. The aim of this study was to employ the quality control parameters in the evaluation of flowers of M. philippica L. The flowers were collected, identified, air dried and pulverized. Standard procedures were carried out to obtain microscopic features of the fresh and powdered samples, micromeritic, chemomicroscopy, flourescence properties, soluble-extractive values, moisture content and ash values. The results of the microscopic studies using the fresh and powdered flower revealed the presence of paracytic and anomocytic stomata on the abaxial surface of the flower (hypostomatic) and none on the adaxial. The abaxial surface also had a stomatal number of 13.6, stomatal index of 4.97% and epidermal number of 260.8 while the adaxial surface had an epidermal number of 304.4. The plant samples of the flower also possessed unicellular trichomes. Results of the micromeritic properties of the samples were bulk volume of 67.16±0.16, tapped volume of 48.00±0.57, bulk density of 0.14±0.00, tapped density of 0.20±0.00, angle of repose of 38.5°, Carr’s Index of 28.50±0.81 and Hausner’s ratio of 1.39±0.01. Chemomicroscopy study showed cellulose, mucilage and protein. The moisture content values obtained was13%w/w. Results for the total ash, acid-insoluble ash and water-soluble ash values were 7.7%w/w, 1.3%w/w and 4%w/w and for the ethanol-soluble, methanol-soluble and water-soluble extractive values were 33%w/w, 33%w/w and 36%w/w. The above results could be used to establish pharmacopoeial standards for both fresh and powdered flower of M. philippica.
{"title":"Micromorphological and Pharmacognostic Studies of Mussaenda philippica L. Flower","authors":"R. Umoh, I. Johnny, N. Andy, Anwanabasi E. Udoh, Trust E. Ekpo, Gabriel U. Ashibeshi","doi":"10.9734/jocamr/2023/v23i4483","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v23i4483","url":null,"abstract":"Mussaenda philippica Linn. belongs to the sub-family Ixoroideae which belongs to the family Rubiaceae. The aim of this study was to employ the quality control parameters in the evaluation of flowers of M. philippica L. The flowers were collected, identified, air dried and pulverized. Standard procedures were carried out to obtain microscopic features of the fresh and powdered samples, micromeritic, chemomicroscopy, flourescence properties, soluble-extractive values, moisture content and ash values. The results of the microscopic studies using the fresh and powdered flower revealed the presence of paracytic and anomocytic stomata on the abaxial surface of the flower (hypostomatic) and none on the adaxial. The abaxial surface also had a stomatal number of 13.6, stomatal index of 4.97% and epidermal number of 260.8 while the adaxial surface had an epidermal number of 304.4. The plant samples of the flower also possessed unicellular trichomes. Results of the micromeritic properties of the samples were bulk volume of 67.16±0.16, tapped volume of 48.00±0.57, bulk density of 0.14±0.00, tapped density of 0.20±0.00, angle of repose of 38.5°, Carr’s Index of 28.50±0.81 and Hausner’s ratio of 1.39±0.01. Chemomicroscopy study showed cellulose, mucilage and protein. The moisture content values obtained was13%w/w. Results for the total ash, acid-insoluble ash and water-soluble ash values were 7.7%w/w, 1.3%w/w and 4%w/w and for the ethanol-soluble, methanol-soluble and water-soluble extractive values were 33%w/w, 33%w/w and 36%w/w. The above results could be used to establish pharmacopoeial standards for both fresh and powdered flower of M. philippica.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83430832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-08DOI: 10.9734/jocamr/2023/v23i3481
I. Johnny, E. E. Ubengama, R. Umoh, O. Obasi, A. Udobre, A. M. Adefabi, N. Andy, E. J. Udofa, P. A. Iberi, E. Nyong, U. T. Nweke, M. Bassey
Background and Aim: Cola pachycarpa K. Schum. is a lesser-known member of the genus Cola called “Monkey kola” in the family Malvaceae. The leaf and fruit is used in the treatment and management of cancer in folklore medicine. The present study is carried out to explore the phytoconstituents present in the ethanolic extract of the leaf and stem of Cola pachycarpa by GC-MS analysis. Methods: Leaf and stem were collected, identified, sliced, air-dried, pulverized, extracted with ethanol and concentrated using standard methods. The ethanolic extract of the extracts was used for the GC-MS analysis. QP2010SE Shimazu, Japan System GC-MS was used for the analysis. The compounds were identified by the gas chromatography coupled with the mass spectrometry. The molecular weight and structure of the compounds of test materials are ascertained by interpretation of the mass spectrum of GC-MS using the database of National Institute Standard and Technology (NIST). Results: GC-MS analysis of the leaf and stem ethanol extracts of C. pachycarpa revealed the presence of 64 and 47 chemical constituents respectively which includes 1-propanol, 2-amino-2-methyl (31.34%), undecanal, 2-methyl (4.00%), phenol, 2,6-dimethoxy (4.18%), n-Hexadecanoic acid (3.35%) and vitamin E (5.15%) and the most abundant in the stem extract were: 1,4-Benzodioxin-6-sulfonamide,N-[2-(dimethylamino)ethyl- (30.10%), .alpha.D-Galactopyranoside, methyl (12.56%), Phenethylamine,.alpha.-ethyl- (10.96%), 4-Methylpiperazine-2-carboxylic acid (5.78%) and Guanosine (3.86%). Conclusion: The presence of various bioactive compounds may be responsible for the application of Cola pachycarpa in the treatment and management of various ailments in folklore medicine. However, in vitro and in vitro studies, isolation of individual phytoconstituents and their mechanism of action may proceed to find a novel drug or lead compound for use as medicine.
背景与目的:可乐pachycarpa K. Schum。是一种不太为人所知的可乐属成员，被称为“猴子可乐”，属于malvacae科。其叶和果在民间医学中用于癌症的治疗和管理。本研究采用气相色谱-质谱联用分析的方法对可乐叶和茎乙醇提取物中存在的植物成分进行了研究。方法:采集叶和茎，鉴定，切片，风干，粉碎，乙醇提取，浓缩，采用标准方法。提取液的乙醇提取物用于GC-MS分析。采用QP2010SE Shimazu, Japan System GC-MS进行分析。用气相色谱联用质谱法对化合物进行了鉴定。采用美国国家标准与技术研究院(NIST)数据库对气相色谱-质谱进行解释，确定了测试材料化合物的分子量和结构。结果:经气相色谱-质谱分析，粗木叶和茎乙醇提取物中分别含有64种和47种化学成分，分别为1-丙醇、2-氨基-2-甲基(31.34%)、十一醛、2-甲基(4.00%)、苯酚、2,6-二甲氧基(4.18%)、正十六酸(3.35%)和维生素E(5.15%)。粗木茎提取物中含量最高的化学成分为:1,4-苯并二氧辛-6-磺酰胺、N-[2-(二甲氨基)乙基-(30.10%)、α。d -半乳糖苷，甲基(12.56%)，苯乙胺，α。-乙基-(10.96%)、4-甲基哌嗪-2-羧酸(5.78%)和鸟苷(3.86%)。结论:茯苓多糖中多种活性成分的存在可能是其在民间医学中治疗和管理多种疾病的重要原因。然而，在离体和离体研究中，对单个植物成分及其作用机制的分离可能会进一步发现一种新的药物或先导化合物作为药物使用。
{"title":"Phytochemical Profile of Cola pachycarpa K. Schum. (Malvaceae) Leaf and Stem Ethanol Extracts","authors":"I. Johnny, E. E. Ubengama, R. Umoh, O. Obasi, A. Udobre, A. M. Adefabi, N. Andy, E. J. Udofa, P. A. Iberi, E. Nyong, U. T. Nweke, M. Bassey","doi":"10.9734/jocamr/2023/v23i3481","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v23i3481","url":null,"abstract":"Background and Aim: Cola pachycarpa K. Schum. is a lesser-known member of the genus Cola called “Monkey kola” in the family Malvaceae. The leaf and fruit is used in the treatment and management of cancer in folklore medicine. The present study is carried out to explore the phytoconstituents present in the ethanolic extract of the leaf and stem of Cola pachycarpa by GC-MS analysis. \u0000Methods: Leaf and stem were collected, identified, sliced, air-dried, pulverized, extracted with ethanol and concentrated using standard methods. The ethanolic extract of the extracts was used for the GC-MS analysis. QP2010SE Shimazu, Japan System GC-MS was used for the analysis. The compounds were identified by the gas chromatography coupled with the mass spectrometry. The molecular weight and structure of the compounds of test materials are ascertained by interpretation of the mass spectrum of GC-MS using the database of National Institute Standard and Technology (NIST). \u0000Results: GC-MS analysis of the leaf and stem ethanol extracts of C. pachycarpa revealed the presence of 64 and 47 chemical constituents respectively which includes 1-propanol, 2-amino-2-methyl (31.34%), undecanal, 2-methyl (4.00%), phenol, 2,6-dimethoxy (4.18%), n-Hexadecanoic acid (3.35%) and vitamin E (5.15%) and the most abundant in the stem extract were: 1,4-Benzodioxin-6-sulfonamide,N-[2-(dimethylamino)ethyl- (30.10%), .alpha.D-Galactopyranoside, methyl (12.56%), Phenethylamine,.alpha.-ethyl- (10.96%), 4-Methylpiperazine-2-carboxylic acid (5.78%) and Guanosine (3.86%). \u0000Conclusion: The presence of various bioactive compounds may be responsible for the application of Cola pachycarpa in the treatment and management of various ailments in folklore medicine. However, in vitro and in vitro studies, isolation of individual phytoconstituents and their mechanism of action may proceed to find a novel drug or lead compound for use as medicine.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"191 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85005326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-04DOI: 10.9734/jocamr/2023/v23i3479
T. Suryowati, Batara Sirait, L. Zabrina
Preeclampsia, known as the "new onset of persistent hypertension," can increase the morbidity and mortality of mothers and fetus. The Indonesian Health Profile shows that the maternal mortality rate (MMR) due to preeclampsia in Indonesia reaches 25%. The Corona Virus Disease 2019 impacted the access to, and quality health services, including for maternal and neonatal. This study aim to determine the risk factors for preeclampsia at Budhi Asih Hospital during the Covid-19 pandemic. This was a retrospective, observational case-controlled study, using medical records of woman on antenatal care from March 2020 – March 2022. Samples size was 128 participants (64 cases and 64 controls) using a simple random technique. Data analysis used the Chi-square test and logistic regression. The results showed that the variables associated with the incidence of preeclampsia were maternal age (p=0.049), parity status (p=0.041), chronic hypertension (p=0.000), and BMI (p=0.003). Variables that were not related to the incidence of preeclampsia were previous history of preeclampsia (p=0.094), pregnancy interval (p=0.367), and family history of preeclampsia (p=0.154). The most dominant variable was chronic hypertension (OR 36.162; 95% CI 4.453-293.655). This study concludes that chronic hypertension, obesity, age at risk (<20 years or >35 years), and nullipara or primipara are risk factors for preeclampsia at Budhi Asih Hospital during the Covid-19 pandemic.
先兆子痫被称为“持续性高血压的新发”，可增加母亲和胎儿的发病率和死亡率。《印度尼西亚健康概况》显示，印度尼西亚因先兆子痫导致的产妇死亡率(MMR)达到25%。2019年冠状病毒病影响了包括孕产妇和新生儿在内的人们获得高质量卫生服务的机会。本研究旨在确定Covid-19大流行期间Budhi Asih医院先兆子痫的危险因素。这是一项回顾性、观察性病例对照研究，使用了2020年3月至2022年3月期间妇女产前护理的医疗记录。采用简单的随机技术，样本量为128名参与者(64例和64例对照)。数据分析采用卡方检验和logistic回归。结果显示，与子痫前期发生率相关的变量为产妇年龄(p=0.049)、胎次状况(p=0.041)、慢性高血压(p=0.000)和BMI (p=0.003)。与子痫前期发生率无关的变量为子痫前期病史(p=0.094)、妊娠间隔(p=0.367)、子痫前期家族史(p=0.154)。最主要的变量是慢性高血压(OR 36.162;95% ci 4.453-293.655)。本研究得出结论，慢性高血压、肥胖、危险年龄(35岁)、无产或初产是Covid-19大流行期间Budhi Asih医院发生子痫前期的危险因素。
{"title":"Risk Factors of Body Mass Index and Hypertension on Preeclampsia during the Covid-19 Pandemic","authors":"T. Suryowati, Batara Sirait, L. Zabrina","doi":"10.9734/jocamr/2023/v23i3479","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v23i3479","url":null,"abstract":"Preeclampsia, known as the \"new onset of persistent hypertension,\" can increase the morbidity and mortality of mothers and fetus. The Indonesian Health Profile shows that the maternal mortality rate (MMR) due to preeclampsia in Indonesia reaches 25%. The Corona Virus Disease 2019 impacted the access to, and quality health services, including for maternal and neonatal. This study aim to determine the risk factors for preeclampsia at Budhi Asih Hospital during the Covid-19 pandemic. This was a retrospective, observational case-controlled study, using medical records of woman on antenatal care from March 2020 – March 2022. Samples size was 128 participants (64 cases and 64 controls) using a simple random technique. Data analysis used the Chi-square test and logistic regression. The results showed that the variables associated with the incidence of preeclampsia were maternal age (p=0.049), parity status (p=0.041), chronic hypertension (p=0.000), and BMI (p=0.003). Variables that were not related to the incidence of preeclampsia were previous history of preeclampsia (p=0.094), pregnancy interval (p=0.367), and family history of preeclampsia (p=0.154). The most dominant variable was chronic hypertension (OR 36.162; 95% CI 4.453-293.655). This study concludes that chronic hypertension, obesity, age at risk (<20 years or >35 years), and nullipara or primipara are risk factors for preeclampsia at Budhi Asih Hospital during the Covid-19 pandemic.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84808693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-04DOI: 10.9734/jocamr/2023/v23i3478
Chyntia Monalisa Sahetapi, Christina Aritonang
Stroke is the second most common cause of death and the leading cause of disability worldwide. Hemorrhagic stroke occurs in 15% of stroke cases. Increased leukocyte counts in the acute phase of hemorrhagic stroke are believed to be related to the incidence of early neurological deterioration. This study aims to determine the relationship between increased leukocyte count and early neurological deterioration in hemorrhagic stroke patients while being treated at UKI General Hospital. This research is analytic research with a cross-sectional design. There were 38 research subjects. The sample was selected using total sampling with specified inclusion and exclusion criteria. The study subjects were grouped into leukocytosis with leukocyte values > 11,000/µL blood and normoleukocytes with leukocyte ranges ranging from 4000-11000/µL blood. The data used is secondary data. The results of the study were processed using the SPSS computer program. It was found that early neurological deterioration in patients with leukocytosis was significantly higher than in patients with normoleucosis, with a Relative Risk of early neurological deterioration in patients with leukocytosis of 3.003 (CI 95%); p=0.031). A significant relationship exists between increased leukocyte count (leukocytosis) upon admission and early neurological deterioration while being treated for hemorrhagic stroke patients at the UKI General Hospital.
{"title":"Correlation between Increased Leukocyte Counts in Patients with Acute Phase Hemorrhagic Stroke with Early Neurological Deterioration Events","authors":"Chyntia Monalisa Sahetapi, Christina Aritonang","doi":"10.9734/jocamr/2023/v23i3478","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v23i3478","url":null,"abstract":"Stroke is the second most common cause of death and the leading cause of disability worldwide. Hemorrhagic stroke occurs in 15% of stroke cases. Increased leukocyte counts in the acute phase of hemorrhagic stroke are believed to be related to the incidence of early neurological deterioration. This study aims to determine the relationship between increased leukocyte count and early neurological deterioration in hemorrhagic stroke patients while being treated at UKI General Hospital. This research is analytic research with a cross-sectional design. There were 38 research subjects. The sample was selected using total sampling with specified inclusion and exclusion criteria. The study subjects were grouped into leukocytosis with leukocyte values > 11,000/µL blood and normoleukocytes with leukocyte ranges ranging from 4000-11000/µL blood. The data used is secondary data. The results of the study were processed using the SPSS computer program. It was found that early neurological deterioration in patients with leukocytosis was significantly higher than in patients with normoleucosis, with a Relative Risk of early neurological deterioration in patients with leukocytosis of 3.003 (CI 95%); p=0.031). A significant relationship exists between increased leukocyte count (leukocytosis) upon admission and early neurological deterioration while being treated for hemorrhagic stroke patients at the UKI General Hospital.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78689539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-03DOI: 10.9734/jocamr/2023/v23i3476
Frisca Ronauli Batubara, Marjasa D. Dicky Newton
The correlation between the use of contact lens cleaning solutions with subjective complaints of the contact lens users in the medical student Batch 2018 Christian University of Indonesia. The research aims to determine the correlation between duration of use, knowledge, and obedience to contact lens cleaning solutions with subjective complaints of contact lens users. Samples were taken from 40 students of contact lens users by filling out a questionnaire containing duration of use, knowledge, and obedience use of contact lens cleaning solution. The result of the study is that the correlation between the duration of use of contact lens cleaning solution and knowledge of use of contact lens cleaning solution with subjective complaints of the contact lens users is not significant. The correlation between obedience use of contact lens cleaning solutions with subjective complaints of contact lens users is significant.
{"title":"Correlation between Use of Contact Lens Cleaning Liquid and Subjective Complaints of the Eyes of Contact Lens Users","authors":"Frisca Ronauli Batubara, Marjasa D. Dicky Newton","doi":"10.9734/jocamr/2023/v23i3476","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v23i3476","url":null,"abstract":"The correlation between the use of contact lens cleaning solutions with subjective complaints of the contact lens users in the medical student Batch 2018 Christian University of Indonesia. The research aims to determine the correlation between duration of use, knowledge, and obedience to contact lens cleaning solutions with subjective complaints of contact lens users. Samples were taken from 40 students of contact lens users by filling out a questionnaire containing duration of use, knowledge, and obedience use of contact lens cleaning solution. The result of the study is that the correlation between the duration of use of contact lens cleaning solution and knowledge of use of contact lens cleaning solution with subjective complaints of the contact lens users is not significant. The correlation between obedience use of contact lens cleaning solutions with subjective complaints of contact lens users is significant.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82606515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-03DOI: 10.9734/jocamr/2023/v23i3477
M. O. Enemali, Ikonomopoulos John, Muhammed H. Abdullahi, H. Sunday, Iko A. Danjuma, Ejiogu I. Chibueze
The current study was aimed at determining the phytochemical composition and the effects of Phyllantus urinaria Ethanol extract on the liver and kidneys by using albino rats as the animal models. All the analyses were carried out following standard laboratory methods and procedures. A total of fifteen rats were randomly distributed into three groups of five rats in each group where group one served as the control while the test groups comprise of 1000mg/kg body weight (b.w) and 500mg/kg b.w administered daily for fourteen days and followed by administration of a high dose of paracetamol (200mg/kg b.w) to challenge the system toxicologically. This was deliberately done to note whether the extract having administered for many days will protect the liver and kidneys against the paracetamol by determining the serum biomarkers. The results showed the presence of saponins (8.84 g/100g), tannins (1.32 g/100g), phenols (0.11 g/100g), flavonoids (0.512 g/100g) and alkaloids (0.038 g/100g) while cardiac glycosides, Resins, terpenoids and steroids were not detected. The activity of ALP was significantly (p < 0.05) higher in both the 1000mg/kg b.w and 500mg/kg b.w. There was no significant (p>0.05) decrease in ALT activity of 1000mg/kg b.w and at 500mg/kg b.w. the activity of ALT significant (p>0.05) increased when compared with the control. There was a significant (p<0.05) decrease in AST activity of 1000mg/kg b.w and 500mg/kg b.w when compared with the control. Bilirubin concentration significantly (p< 0.05) decreased at 1000mg/kg b.w and non-significantly (p>0.05) increased at 500mg/kg b.w. ALB significantly (p > 0.05) increased at 1000mg/kg b.w and 500mg/kg b.w. A non-significant decrease in Serum HCO3- in both 1000mg/kg/b.w and 500mg/kg b.w. Urea non-significantly decreased at both 1000mg/kg b.w and 500mg/kg b.w. Creatinine significantly increased at both 1000mg/kg b.w and 500mg/kg b.w concentration when compared to the control. Na+ showed a non-significant increase at 1000mg/kg b.w and 500mg/kg b.w when compared to the control. The extract may not have protected the liver and kidneys against paracetamol despite the presence of some phytochemicals, a histological examination of the liver and kidneys is therefore recommended so as to have a clearer picture of the effects observed.
{"title":"Determination of Phytochemical Composition and the Effects of Ethanol Extract of Phyllanthus urinaria on the Liver and Kidney Function Parameters in Paracetamol-Administered Albino Rat Models","authors":"M. O. Enemali, Ikonomopoulos John, Muhammed H. Abdullahi, H. Sunday, Iko A. Danjuma, Ejiogu I. Chibueze","doi":"10.9734/jocamr/2023/v23i3477","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v23i3477","url":null,"abstract":"The current study was aimed at determining the phytochemical composition and the effects of Phyllantus urinaria Ethanol extract on the liver and kidneys by using albino rats as the animal models. All the analyses were carried out following standard laboratory methods and procedures. A total of fifteen rats were randomly distributed into three groups of five rats in each group where group one served as the control while the test groups comprise of 1000mg/kg body weight (b.w) and 500mg/kg b.w administered daily for fourteen days and followed by administration of a high dose of paracetamol (200mg/kg b.w) to challenge the system toxicologically. This was deliberately done to note whether the extract having administered for many days will protect the liver and kidneys against the paracetamol by determining the serum biomarkers. The results showed the presence of saponins (8.84 g/100g), tannins (1.32 g/100g), phenols (0.11 g/100g), flavonoids (0.512 g/100g) and alkaloids (0.038 g/100g) while cardiac glycosides, Resins, terpenoids and steroids were not detected. The activity of ALP was significantly (p < 0.05) higher in both the 1000mg/kg b.w and 500mg/kg b.w. There was no significant (p>0.05) decrease in ALT activity of 1000mg/kg b.w and at 500mg/kg b.w. the activity of ALT significant (p>0.05) increased when compared with the control. There was a significant (p<0.05) decrease in AST activity of 1000mg/kg b.w and 500mg/kg b.w when compared with the control. Bilirubin concentration significantly (p< 0.05) decreased at 1000mg/kg b.w and non-significantly (p>0.05) increased at 500mg/kg b.w. ALB significantly (p > 0.05) increased at 1000mg/kg b.w and 500mg/kg b.w. A non-significant decrease in Serum HCO3- in both 1000mg/kg/b.w and 500mg/kg b.w. Urea non-significantly decreased at both 1000mg/kg b.w and 500mg/kg b.w. Creatinine significantly increased at both 1000mg/kg b.w and 500mg/kg b.w concentration when compared to the control. Na+ showed a non-significant increase at 1000mg/kg b.w and 500mg/kg b.w when compared to the control. The extract may not have protected the liver and kidneys against paracetamol despite the presence of some phytochemicals, a histological examination of the liver and kidneys is therefore recommended so as to have a clearer picture of the effects observed.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75960036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-03DOI: 10.9734/jocamr/2023/v23i2475
Tiroy Sari B. Simanjuntak, Ganda Pariama
A complicated stroke of hypertension is dreaded in the community. Hypertension is the most common in public and causes no symptoms. Hypertension is one of the risks of stroke. Hypertension can cause injury to the veins of one of the injured blood vessels in the brain because of carelessness, deafness, and narrowing or rupture of blood vessels in the brain and can result in the brain. Nerve damage in this brain causes a stroke. The writer to know the greatest risk factors for stroke patients in hospital UKI in 2019-2021.
{"title":"Relationship between Blood Pressure and Stroke Rate at UKI Hospital","authors":"Tiroy Sari B. Simanjuntak, Ganda Pariama","doi":"10.9734/jocamr/2023/v23i2475","DOIUrl":"https://doi.org/10.9734/jocamr/2023/v23i2475","url":null,"abstract":"A complicated stroke of hypertension is dreaded in the community. Hypertension is the most common in public and causes no symptoms. Hypertension is one of the risks of stroke. Hypertension can cause injury to the veins of one of the injured blood vessels in the brain because of carelessness, deafness, and narrowing or rupture of blood vessels in the brain and can result in the brain. Nerve damage in this brain causes a stroke. The writer to know the greatest risk factors for stroke patients in hospital UKI in 2019-2021.","PeriodicalId":15398,"journal":{"name":"Journal of Complementary and Alternative Medical Research","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136267244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：