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The Impact of Barley-based diet on Diabetes: A Case-Report 以大麦为基础的饮食对糖尿病的影响:一个病例报告
Pub Date : 2023-08-01 DOI: 10.9734/jocamr/2023/v23i2480
S. A. Asha, M. Kavita
Background: Diabetes is becoming more prevalent in India. The increase in prevalence in most populations has probably been driven by modifiable risk factors, including lack of exercise and an increasing prevalence of overweight/obesity and unhealthy diets and habits. Yava(Barley)is one among the food articles and its preparation is extensively suggested in Prameha(Diabetes) and other lifestyle disorders. Diet intervention is the primary and effective way to control sugar levels. Diet therapy without much alteration of one’s habits will be acceptable to individuals. A barley-based diet is formulated and evaluated for its effectiveness in the case of diabetics. Aim: To study the effectiveness of a Yava-based diet on fasting and postprandial blood sugars, fasting and postprandial urine sugars and lipid profile.  Study Design: Modified crossover study Place and Duration of the Study: Department of Swasthavritta, Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan, between December 2022 and February 2023. Methodology: A single case study was designed and a barley-based diet was planned as a flatbread, suggested for a month as a dietetic intervention along with the routine dietary habit. The diabetic subject was screened in the outpatient department. Laboratory investigations were carried out at one-month intervals three times. Subject studied for observation period and intervention period with the follow-ups.  Results: There were decreases in blood sugar and urine sugar levels and in lipid profile. Symptoms like polyphagia, heaviness in the body are also reduced. Conclusion: Ayurveda literature opines Prameha is a disease of vitiated Kapha and fat tissue. Yava has the properties of pacifying Kapha and fat. The diet plan acts as a potential antidiabetic food. Yava can be an alternative to other grains and more beneficial for diabetes.
背景:糖尿病在印度变得越来越普遍。在大多数人群中,患病率的上升可能是由可改变的风险因素造成的,包括缺乏锻炼和超重/肥胖的日益流行以及不健康的饮食和习惯。Yava(大麦)是其中一种食物,它的制备被广泛建议用于糖尿病和其他生活方式紊乱。饮食干预是控制血糖水平的主要和有效的方法。不太改变习惯的饮食疗法对个人来说是可以接受的。制定了以大麦为基础的饮食,并对其在糖尿病患者中的有效性进行了评估。目的:研究以yava为基础的饮食对空腹和餐后血糖、空腹和餐后尿糖和血脂的影响。研究设计:修改交叉研究地点和研究时间:2022年12月至2023年2月期间,阿育吠陀学院和哈桑医院的swasasavritta系。方法:设计了一个单独的案例研究,并计划了一个以大麦为基础的饮食,作为一个月的饮食干预,与常规饮食习惯一起。糖尿病患者在门诊进行筛查。实验室调查每隔一个月进行三次。受试者分为观察期和干预期,并进行随访。结果:血糖、尿糖、血脂均有下降。多食症、身体沉重等症状也会减轻。结论:阿育吠陀文献认为Prameha是Kapha和脂肪组织被破坏的疾病。雅瓦有安抚卡法和脂肪的特性。该饮食计划作为一种潜在的抗糖尿病食品。木薯可以作为其他谷物的替代品,对糖尿病更有益。
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引用次数: 0
Health Assessment of the Ikwerres and Okrikas Ethnic Group of Rivers State, Nigeria: Using Body Mass Index and Waist-to-Hip Ratio 尼日利亚河流州Ikwerres和Okrikas族群的健康评估:使用身体质量指数和腰臀比
Pub Date : 2023-07-31 DOI: 10.9734/jocamr/2023/v23i2474
Nicholas Asiwe, Faustina Chiamaka Irozulike, Lenton Igwangi Wariboko, Oghenefego Michael Adheke
Background: Body mass index (BMI), and waist-to-hip ratio (WHR), are acceptable indicators in accessing health status that are used to assess cardiometabolic disorders and to predict future health risks. The aim of the study assesses the health status of Ikwerres and Okrikas ethnic groups using BMI and WHR. Methods: The study adopted a descriptive cross-sectional study design where it comprises of 300 respondents (139 females and 161 males) between the age of 18-37 years were randomly selected. BMI was deduced from the division of body weight by the square root of standing height and WHR by direct division of waist circumference and hip circumference. Results: A study of 300 subjects from Ikwerre and Okrika ethnic groups in Rivers State found that 11.8% were underweight, 76.4% normal weight, 7.5% overweight, and 4.3% obese in males. The association of BMI was significant with gender differences, and the waist-to-hip ratio showed that 69.6% of males were within the normal range. BMI and waist-to-hip ratio are significant. Conclusion: BMI shows gender differences and the association between BMI and WHR is significant.
背景:身体质量指数(BMI)和腰臀比(WHR)是可接受的健康状况指标,用于评估心脏代谢紊乱和预测未来健康风险。本研究的目的是利用BMI和WHR来评估伊克维尔族和奥克里卡族的健康状况。方法:采用描述性横断面研究设计,随机抽取年龄在18-37岁之间的300名调查对象(女性139人,男性161人)。BMI由体重除以站高的平方根,腰臀围直接除以腰臀围而得。结果:一项对300名来自河流州伊克维尔族和奥克里卡族的研究发现,11.8%的男性体重不足,76.4%的男性体重正常,7.5%的男性超重,4.3%的男性肥胖。BMI与性别差异的相关性显著,腰臀比显示69.6%的男性在正常范围内。身体质量指数和腰臀比很重要。结论:BMI存在性别差异,BMI与腰臀比的相关性显著。
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引用次数: 0
Black Seeds (Nigella sativa) for the Management of COVID-19 in Pregnant and Breastfeeding Women: An Insight 黑籽(Nigella sativa)用于管理孕妇和哺乳期妇女的COVID-19:一种见解
Pub Date : 2023-07-29 DOI: 10.9734/jocamr/2023/v23i2473
N. Maideen, T. Hadda, F. Almalki, Mohammed Moueqquit, S. Kawsar
Aims: About 10% of pregnant women were suspected or confirmed with SARS-CoV-2 infection, while the risk of admission to the intensive care unit (ICU) and the use of invasive mechanical ventilation reach up to ~ 5%. This review aimed to discuss the potential of black seeds (Nigella sativa) in the management of COVID-10 in pregnant and breastfeeding women. Nigella sativa is a medicinal cum nutraceutical herb that is used in many traditional medicine systems to manage several ailments including asthma, back pain, headache, and many others.  Methodology: Online databases such as LitCOVID, Web of Science, Google Scholar, bioRxiv, medRxiv, Science Direct, EBSCO, Scopus, and EMBASE were searched to identify all scientific data relevant to the use of N. sativa in the treatment of COVID-19 pregnant patients. The safety and efficacy of N. sativa and thymoquinone were reported in different experimental studies on pregnant as well as lactating animals. Moreover, several clinical studies and in silico molecular docking studies demonstrated the potential of N. sativa in the management of COVID-19. Results: The data indicate that N. sativa seeds in powdered or oil form can be employed as a potential adjunct therapy to manage COVID-19 in pregnant and lactating women to prevent disease severity and hospitalizations. Conclusion: Based on these results, pregnant women with COVID-19 may use powdered N. sativa seeds or oil as adjunctive therapy along with standard care, to prevent severe illnesses and hospitalizations.
目的:约10%的孕妇怀疑或确诊为SARS-CoV-2感染,而进入重症监护病房(ICU)和使用有创机械通气的风险高达~ 5%。本综述旨在探讨黑籽(Nigella sativa)在孕妇和哺乳期妇女治疗COVID-10中的潜力。黑草是一种药用兼营养草药,在许多传统医学系统中用于治疗几种疾病,包括哮喘、背痛、头痛和许多其他疾病。方法:检索LitCOVID、Web of Science、Google Scholar、bioRxiv、medRxiv、Science Direct、EBSCO、Scopus和EMBASE等在线数据库,确定与使用sativa治疗COVID-19妊娠患者相关的所有科学数据。在怀孕和哺乳动物的不同实验研究中,报道了sativa和百里醌的安全性和有效性。此外,一些临床研究和硅分子对接研究证明了油菜在COVID-19治疗中的潜力。结果:数据表明,粉末状或油状的sativa种子可作为一种潜在的辅助疗法,用于管理孕妇和哺乳期妇女的COVID-19,以预防疾病严重程度和住院治疗。结论:基于这些结果,感染COVID-19的孕妇可以使用亚麻籽粉或油作为标准护理的辅助治疗,以防止严重疾病和住院治疗。
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引用次数: 0
Qualitative and Quantitative Phytochemical Characterization of Leaf Extracts of Mimosa pudica (Mimosaceae) 含羞草(含羞草科)叶片提取物的定性和定量植物化学特征
Pub Date : 2023-07-19 DOI: 10.9734/jocamr/2023/v23i2472
Mas’-Ud Hayatou, E. Tembe, Bayaga Herve, Njinkio Nono Borgia, C. Fokunang
Mimosa pudica is a plant of the Mimosaceae family which is a family composed of several species. It has many pharmacological properties described in Ayurvedic medicine, including the hepatoprotective property which is the subject of this study. The objective of this study was to qualitatively and quantitatively evaluate the secondary metabolites presents in M. pudica leaf extracts. After performing an extraction according to the methods described by Fonmboh et al, we carried out a qualitative analysis in each extract according to the methods described by Shaik et al. The quantitative analysis consisted of a determination of each metabolite in comparison with references. This study was able to show the presence of metabolites such as alkaloids, flavonoids, polyphenols in leaves extracts. The quantification of these metabolites showed a much higher concentration of alkaloids in the extract obtained by hydro-ethanolic maceration of 698.33 ± 8.82µg/ml, in the extract obtained by decoction a higher concentration of polyphenols and flavonoids respectively of 193.87 ± 12.66 µg/ml and 72.90 ± 2.45 µg/ml. This study demonstrated a promising richness in secondary metabolites in M.pudia leaf extracts qualitatively and quantitatively.
含羞草是含羞草科的一种植物,含羞草科是一个由几个物种组成的科。它具有阿育吠陀医学中描述的许多药理特性,包括保护肝脏的特性,这是本研究的主题。本研究的目的是定性和定量评价苦参叶提取物的次生代谢物。在按照Fonmboh等人描述的方法进行提取后,我们按照Shaik等人描述的方法对每个提取物进行定性分析。定量分析包括与参考文献比较每种代谢物的测定。本研究能够证明在叶提取物中存在代谢物,如生物碱、类黄酮、多酚。结果表明,水乙醇浸提液中生物碱含量为698.33±8.82µg/ml,水煎提液中多酚类物质含量为193.87±12.66µg/ml,黄酮类物质含量为72.90±2.45µg/ml。本研究从定性和定量两方面证明了杜仲叶提取物具有丰富的次生代谢产物。
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引用次数: 0
Clinical Effectiveness of Hawthorn, Lemon Balm and Magnesium on Patients with Distress Disorders: Preliminary Data by a Survey of Italian Gastroenterologists 山楂、柠檬香膏和镁对痛苦障碍患者的临床疗效:意大利胃肠病学家调查的初步数据
Pub Date : 2023-07-15 DOI: 10.9734/jocamr/2023/v23i1471
P. Usai-Satta, F. Monica
Aims: distress disorders (DD) include psychological symptoms such as sleep disorders, fatigue and psychophysical exhaustion that are common to many mental diseases. DD is often associated with somatic symptoms such as abdominal pain or bowel dysfunction. The aim of this study was to evaluate in patients with DD the effectiveness of a nutraceutical containing Hawthorn, Lemon Balm, and Magnesium (Vagostabil®) on psychological and abdominal symptoms. For this purpose, a clinical survey was conducted by 7 Italian gastroenterologists. Methodology: 85 patients with DD (60 F, mean age 51,6 yrs), identified by a score > 18 based on the Hamilton Anxiety Rating Scale (HAM-A), were included in the study. All patients assumed Vagostabil®, three tablets a day for two months. The same HAM-A score and a VAS score for abdominal pain were used to measure clinical results. Results: the mean score of the HAM-A scale decreased from 28.61 to 18.22 after 1 month and to 11.46 after 2 months of treatment respectively (P = .001 for all comparisons). An overall reduction of HAM-A score by 59.94 % was observed at the end of the treatment (P = .001). Similarly, VAS score for abdominal pain decreased from 7.59 to 4.86 after 1 month, and to 2.41 at the end of the treatment (P = .001 for both comparisons). A global reduction of 68.25% in the VAS score was observed at the end of the survey (P = .001). Conclusion: this clinical survey showed that Vagostabil® can ameliorate psychological symptoms and associated abdominal pain in patients with DD. These preliminary data suggest that Vagostabil® could be utilized by gastroenterologists in functional gastrointestinal disorders. However, further studies are needed to confirm these data.
目的:痛苦障碍(DD)包括许多精神疾病常见的心理症状,如睡眠障碍、疲劳和身心疲惫。DD常伴有躯体症状,如腹痛或肠功能障碍。本研究的目的是评估含有山楂、柠檬香蜂草和镁的营养保健品(迷走稳定®)对DD患者心理和腹部症状的疗效。为此,7名意大利胃肠病学家进行了一项临床调查。方法:85例DD患者(60岁,平均年龄551岁,6岁),根据汉密尔顿焦虑评定量表(HAM-A)评分> 18分,纳入研究。所有患者服用迷走稳定,每天三片,持续两个月。采用相同的HAM-A评分和VAS评分来衡量腹痛的临床结果。结果:治疗1个月后HAM-A量表平均评分由28.61分降至18.22分,治疗2个月后评分为11.46分(P = 0.001)。在治疗结束时观察到HAM-A评分总体降低59.94% (P = 0.001)。同样,1个月后腹痛VAS评分从7.59降至4.86,治疗结束时降至2.41(两组比较P = 0.001)。在调查结束时观察到VAS评分总体下降68.25% (P = 0.001)。结论:本临床调查显示,迷走他定能改善DD患者的心理症状和相关腹痛。这些初步数据表明,迷走他定可被胃肠病学家用于功能性胃肠疾病。然而,需要进一步的研究来证实这些数据。
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引用次数: 0
Does ABO Blood Type Implicate Susceptibility to Respiratory Abnormalities? A Controlled Cross-sectional Study among Indigenous University Students in Rivers State, Nigeria ABO血型是否与呼吸异常易感性有关?尼日利亚河流州土著大学生的对照横断面研究
Pub Date : 2023-07-15 DOI: 10.9734/jocamr/2023/v23i1470
J. N. Asiwe, E. Umoren, T. Kolawole, K. B. Etim, Adedolapo Adeola Agbeluyi, Nicholas Asiwe, V. Igbokwe
Background: The blood typing is a genetically defined immune system characteristic that has a well-known role in transplantation and chemotherapy. However, it is unclear what role it could serve in diagnosing or predicting respiratory pathologies. The study aims at investigating the prevalence of respiratory disorder among ABO blood type. This study investigated the prevalence of respiratory disorder among ABO blood types. Methods: Using a quantitative survey research design, this cross-sectional study comprises of 102 young University students (64 females and 36 males) within the age of 17-28 years, extracted from different local Government Area in Rivers State. A semi-structured questionnaire was used to gather the social demograpgic characteristics of respondent’s. Anthropometric investigations and respiratory function test was done. Results: The prevalent blood types A, B, O, and AB was 19.6%, 16.7%, 56.9%, and 6.9% respectively. BMI showed that 2.9%, 39.2%, 38.2% and 19.6% was underweight, normal weight, overweight and obese respectively. Respiratory problems were distributed unevenly among blood types, with risk of obstructive pulmonary dysfunction having the highest frequency of occurrence. Conclusion: The susceptibility to respiratory abnormalities is not associated with any blood type, the risk of obstructive pulmonary disease is higher in blood type O, which is largely influenced by the predominancy.
背景:血型是一种遗传定义的免疫系统特征,在移植和化疗中具有众所周知的作用。然而,尚不清楚它在诊断或预测呼吸系统疾病方面的作用。本研究旨在调查ABO血型人群呼吸系统疾病的患病率。本研究调查了ABO血型间呼吸系统疾病的患病率。方法:采用定量调查研究设计,对来自河流州不同地方政府辖区的102名17-28岁的年轻大学生(女64名,男36名)进行横断面研究。采用半结构化问卷收集被调查者的社会人口学特征。进行了人体测量和呼吸功能测试。结果:A型、B型、O型、AB型的患病率分别为19.6%、16.7%、56.9%、6.9%。体重指数显示,体重不足、正常、超重和肥胖分别为2.9%、39.2%、38.2%和19.6%。呼吸系统疾病在不同血型之间的分布不均匀,阻塞性肺功能障碍的发生频率最高。结论:呼吸异常易感性与任何血型无关,O型血发生阻塞性肺疾病的风险较高,主要受优势型的影响。
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引用次数: 0
Impact of Sensory Stimulation on Perception and Performance among the Comatose: A Pilot Study 感觉刺激对昏迷者知觉和表现的影响:一项初步研究
Pub Date : 2023-07-13 DOI: 10.9734/jocamr/2023/v23i1469
Charitha Lewis, D. Lobo
Adult brains in good health are capable of processing a variety of intricate sensory data. The faces of the object and the people are recognised, and the location, depth, and distance of the object and the people are identified. These basic and complex perceptual abilities may be impacted by a stroke or other acquired brain injury, such as a head injury. Being unaware of one's surroundings, as when sleeping, or being unresponsive to stimulation are both symptoms of being unconscious. In the area of neurorehabilitation, sensory stimulation programmes (SSP) have received the most research. A healthcare provider or a family member systematically stimulates the patient's five sensory modalities as part of sensory stimulation, a form of therapy that may improve the patient's responsiveness. In order to analyse the impact of sensory stimulation on perception and performance among comatose, double- blinded randomized clinical trial was conducted on 12 comatose patients with Glasgow Coma Scale score 3-8 and diagnosed with traumatic brain injury and cerebrovascular accidents. The patients were randomly assigned into two groups of experimental and control. The comatose patients were recruited via random sampling from various Intensive Care Units of AJ Institute of Medical Sciences, Mangalore. The experimental group was given sensory stimulation twice daily for seven consecutive days, with each session lasting 25 minutes. By contrast, the control group only received routine care from the hospital. Data was collected via demographic and clinical proforma and level of conscious was measured by Coma Recovery Scale-Revised (CRS-R). For statistical analysis, independent t test and ANOVA were computed. There was a significant increase in the post-test scores of CRS-R for experimental group which revealed that multimodal sensory stimulation effectively increased the CRS-R scores among unconscious patients in the experimental group.  Nurses can use this intervention to improve sensory scores among unconscious patients in the Intensive Care Unit.
健康的成年人大脑能够处理各种复杂的感官数据。识别物体和人的面孔,识别物体和人的位置、深度和距离。这些基本和复杂的感知能力可能会受到中风或其他获得性脑损伤(如头部损伤)的影响。对周围环境没有知觉,如睡觉时,或对刺激没有反应,都是无意识的症状。在神经康复领域,感觉刺激方案(SSP)得到了最多的研究。作为感觉刺激的一部分,医疗保健提供者或家庭成员系统地刺激患者的五种感觉模式,这是一种可能改善患者反应性的治疗形式。为分析感觉刺激对昏迷患者知觉及行为的影响,对12例格拉斯哥昏迷评分3 ~ 8分、诊断为外伤性脑损伤及脑血管意外的昏迷患者进行双盲随机临床试验。患者随机分为实验组和对照组。通过随机抽样从芒格洛尔AJ医学科学研究所各重症监护病房招募昏迷患者。实验组给予感官刺激,每天2次,连续7天,每次25分钟。相比之下,对照组只接受医院的常规护理。通过人口统计学和临床形式收集数据,并通过昏迷恢复量表-修订(CRS-R)测量意识水平。统计分析采用独立t检验和方差分析。实验组的CRS-R测试后得分显著提高,说明多模态感觉刺激有效提高了实验组无意识患者的CRS-R得分。护士可以使用这种干预措施来提高重症监护病房无意识患者的感觉评分。
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引用次数: 0
Phytochemical and Nutritional Constituents of Leaf Extracts of Two Edible Medicinal Plants in Nigeria: A Comparative Appraisal 尼日利亚两种可食用药用植物叶提取物的植物化学和营养成分:比较评价
Pub Date : 2023-07-06 DOI: 10.9734/jocamr/2023/v23i1468
U. Evuen, E. D. Kpomah
Humanity has constantly sought empirical treatments for health problems and nutritional deficits since the 20th century. In this regard, synthetic medications have been in extensive use. However, their applications in such conditions are often accompanied by negative side effects coupled with accounts of the development of resistance, which has driven an increase in the quest for creative alternatives like plant-based medications. Thus, botanicals derived from plants with medicinal attributes are an indispensable component of existence today. They enhance good health particularly for residents in remote areas where access to appropriate nutrition and healthcare is often a challenge. In the present investigation, the phytochemical and nutritional constituents of ethanol leaf extracts of two significant plants with nutritional and therapeutic relevance, Dennettia tripetala, and Aframomum melegueta, were comparatively examined through the exploration of established protocols. In the phytochemical investigation, D. tripetala has a predominance of alkaloids (4.91%), terpenes (3.03%), saponins (3.76%), flavonoids (6.10%), and tannins (5.89%). Contrarily, no significant difference (p> 0.05) was observed in the cardiac glycoside contents of D. tripetala (2.25%), and A. melegueta (2.38%). The proximate data shows a greater proportion of moisture (13.11%), protein (10.54%), fibre (5.01%) and carbohydrate (59.36%) contents in D. tripetala. However, A. melegueta had a greater quantity of ash, and lipids (11.76 %, and 7.46%) than D. tripetala (6.52%, and 5.42%). The elemental assessment of the leaves shows that the concentrations of calcium, magnesium, sodium, potassium, iron, manganese, and phosphorous in A. melegueta were significantly higher (p<0.05) than those of D. tripetala. The opposite results were obtained for the levels of Zinc and Copper in A. melegueta and D. tripetala respectively. Therefore, the differential compositions of the chemical components present in leaf extracts of the two plants have given an insight into the best source of active principles and nutrients among them, to exploit in medicinal preparations and diet formulations for combating diseased conditions induced by pathogenic organisms and nutritional inadequacies respectively.
自20世纪以来,人类一直在寻求治疗健康问题和营养不足的经验疗法。在这方面,合成药物已被广泛使用。然而,在这种情况下,它们的应用往往伴随着负面的副作用,再加上耐药性的发展,这促使人们越来越多地寻求创造性的替代品,如植物性药物。因此,从具有药用属性的植物中提取的植物药是当今存在的不可或缺的组成部分。它们尤其有利于偏远地区居民的健康,因为在这些地区,获得适当的营养和保健往往是一项挑战。在本研究中,通过对两种具有营养和治疗意义的重要植物,Dennettia tripetala和Aframomum melegueta的乙醇叶提取物的植物化学和营养成分进行了比较研究。在植物化学研究中,三瓣草以生物碱(4.91%)、萜烯(3.03%)、皂苷(3.76%)、黄酮类(6.10%)和单宁(5.89%)为主。相反,三瓣草(2.25%)和麻瓜(2.38%)的心苷含量差异不显著(p> 0.05)。近似数据表明,三瓣草的水分(13.11%)、蛋白质(10.54%)、纤维(5.01%)和碳水化合物(59.36%)含量较高。然而,马蹄莲的灰分和脂质含量(分别为11.76%和7.46%)高于马蹄莲(分别为6.52%和5.42%)。叶片元素评价结果表明,毛蕊草的钙、镁、钠、钾、铁、锰、磷含量显著高于三瓣草(p<0.05)。铜和锌的测定结果则相反。因此,这两种植物叶提取物中化学成分的不同组成,使人们了解了其中活性成分和营养成分的最佳来源,可以在药物制剂和饮食配方中加以利用,分别用于对抗病原生物引起的疾病和营养不足。
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引用次数: 0
Homoeopathic Perspective in the Management of Substance Use Disorders: A Systematic Review 顺势疗法在药物使用障碍管理中的应用:系统综述
Pub Date : 2023-07-05 DOI: 10.9734/jocamr/2023/v22i4465
U. Singh, Shweta Singh, H. Ram
Background: Substance abuse has become a widespread global issue. It includes abuse of illegal substances, namely marijuana, heroin, cocaine and methamphetamines, and legal substances, including alcohol, nicotine or prescribed medicines. Aim of Review: This review assesses the role of Homoeopathy in the therapeutic management of substance use disorders (SUD) through a systematic web-based literature search. Methods: A comprehensive search was conducted online and manually to identify homoeopathic research studies published between 1993 and 2022 on SUD in international databases and the Central Council of Research in Homoeopathy library. Relevant studies were categorised and assessed in terms of study designs, number of participants, evidence grades and clinical outcome parameters. A total of 21 full-text studies were screened and evaluated. Risk of bias (RoB) was assessed for all studies and model validity was appraised for the included RCTs'. Results: 10 studies (3 Randomised Controlled Trials, 3 Observational studies, 1 Pilot study, 1 observational comparative study, 1 Retrospective cohort study and 1 case series) were included and 11 studies were excluded with reasons. 03 studies have a level of evidence of 1b with an 'A' grade of recommendation, which consists of the RCTs only. The most commonly prescribed medicines identified were: Arsenic album, Nux vomica, Lycopodium, Pulsatilla, Sulphur, Staphysagria, Belladonna, Ipecac, Chamomilla, Rhustox, Phosphorus and Lachesis. A high risk of bias was elicited in most of the observational studies accentuating the need for more robust methodological studies. Conclusion:  The majority of the studies have a small number of recruitments. Pragmatic studies with larger sample sizes and validated outcome measures may be designed further to validate the promising role of homoeopathic medicines in SUDs and generate quality evidence.
背景:药物滥用已成为一个普遍的全球性问题。它包括滥用非法物质,即大麻、海洛因、可卡因和甲基苯丙胺,以及合法物质,包括酒精、尼古丁或处方药。综述目的:本综述通过系统的网络文献检索,评估顺势疗法在药物使用障碍(SUD)治疗管理中的作用。方法:对国际数据库和顺势疗法研究中央委员会图书馆1993 - 2022年发表的顺势疗法研究进行在线和人工综合检索。根据研究设计、参与者数量、证据等级和临床结果参数对相关研究进行分类和评估。共筛选和评估了21项全文研究。对所有研究进行偏倚风险(RoB)评估,并对纳入的rct进行模型效度评估。结果:纳入10项研究(3项随机对照试验、3项观察性研究、1项先导研究、1项观察性比较研究、1项回顾性队列研究和1项病例系列研究),有原因排除11项研究。03项研究的证据水平为1b,推荐等级为“a”,仅由随机对照试验组成。鉴定出的最常见处方药为:砒霜、马钱子、石蒜、白头翁、硫、葡萄球菌、颠茄、吐根、洋甘菊、猪蹄草、磷和乳香。在大多数观察性研究中引起了高偏倚风险,这突出了对更可靠的方法学研究的需要。结论:大多数研究都有少量的招募。可以进一步设计具有更大样本量和验证结果测量的实用研究,以验证顺势疗法药物在sud中的有希望的作用,并产生高质量的证据。
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引用次数: 0
Naturopathy Module in Management of Obesity (Class-3): A Case Study 自然疗法模块在肥胖管理(三级):一个案例研究
Pub Date : 2023-07-05 DOI: 10.9734/jocamr/2023/v22i4466
R. Chauhan, S. Chauhan, Roshani Tank, Umesh Yadav
Obesity is a complex condition with global prevalence reaching almost one-third of the world's population. It affects all ages, genders, and backgrounds, although older individuals and women tend to be more affected. In this case, a 36-year-old male business person leading a sedentary lifestyle presented with severe obesity (Class-3), hypertension, low back pain, fatigue and umbilical hernia for the past few years. The individual received 30-days of naturopathy treatments and diet intervention program. The treatment was provided through a personalized and customized protocol at Ipcowala naturopathy and yoga center (INYC) a residential naturopathy facility located in Vadodara, Gujarat. The findings indicated a significant reduction in body weight (from 130.74 kg to 116.60 kg), Body Mass Index (BMI) (from 41.76 to 37.25), Blood Pressure (from 140/100 to 130/86), as well as a notable decrease in back pain related disability and fatigue levels on scale. The patient experienced an overall improvement in functional health and reported an enhanced sense of well-being. Notably, the individual exhibited improvements across all domains of the WHO Quality of Life Bref scale. This case study strongly suggests that the naturopathy treatment, a tailored diet plan and fasting can serve as a beneficial intervention for reducing obesity and associated comorbidities. Further large scale studies are needed for observing effect of individual naturopathy therapies. 
肥胖是一种复杂的疾病,全球流行率几乎达到世界人口的三分之一。它影响所有年龄、性别和背景,尽管老年人和女性更容易受到影响。在这个案例中,一位36岁的男性商人,过着久坐不动的生活方式,在过去的几年里出现了严重的肥胖(3级),高血压,腰痛,疲劳和脐疝。个体接受30天的自然疗法和饮食干预计划。治疗是通过Ipcowala自然疗法和瑜伽中心(INYC)的个性化定制方案提供的,该中心是位于古吉拉特邦Vadodara的住宅自然疗法设施。研究结果表明,体重(从130.74公斤降至116.60公斤)、身体质量指数(BMI)(从41.76降至37.25)、血压(从140/100降至130/86)显著降低,背部疼痛相关的残疾和疲劳水平也显著降低。患者经历了功能健康的全面改善,并报告了幸福感的增强。值得注意的是,该个人在世卫组织生活质量简短量表的所有领域都表现出改善。本病例研究强烈表明,自然疗法、量身定制的饮食计划和禁食可以作为减少肥胖和相关合并症的有益干预措施。需要进一步的大规模研究来观察个体自然疗法的效果。
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引用次数: 0
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Journal of Complementary and Alternative Medical Research
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