Pub Date : 2024-05-17DOI: 10.12775/jehs.2024.70.51095
Izabela Staniszewska
Introduction: Systemic sclerosis (SSc) is a chronic multisystem disease. The condition is characterized by extensive vascular dysfunction and progressive fibrosis of the skin and internal organs. The musculoskeletal, cardiac, pulmonary, and gastrointestinal systems are involved, resulting in a broad range of symptoms. Diagnosis is based on skin and/or internal organ fibrosis, production of specific autoantibodies, and evidence of vasculopathy Purpose of work: Synthesis of knowledge about physical activity in patients with SSc. Summary: Exercise and physiotherapy can improve the physical functions of patients with SSc. Physical activity in patients with SSc enhances hand function, enhances the function of the orofacial region, enhances sexual function, and also aids in coping with Raynaund's phenomenon, enhances physical capacity, alleviates fatigue as well and enhances general physical capacity. Furthermore, regular physical activity impeded the natural progression of progressive impairment of functional ability. Although, the literature regarding the efficacy and safety of exercise in patients with SSc is further insufficient.
{"title":"A Role of Physical Activity in Patients with Systemic Sclerosis – a literature review","authors":"Izabela Staniszewska","doi":"10.12775/jehs.2024.70.51095","DOIUrl":"https://doi.org/10.12775/jehs.2024.70.51095","url":null,"abstract":"Introduction: Systemic sclerosis (SSc) is a chronic multisystem disease. The condition is characterized by extensive vascular dysfunction and progressive fibrosis of the skin and internal organs. The musculoskeletal, cardiac, pulmonary, and gastrointestinal systems are involved, resulting in a broad range of symptoms. Diagnosis is based on skin and/or internal organ fibrosis, production of specific autoantibodies, and evidence of vasculopathy \u0000Purpose of work: Synthesis of knowledge about physical activity in patients with SSc. \u0000Summary: Exercise and physiotherapy can improve the physical functions of patients with SSc. Physical activity in patients with SSc enhances hand function, enhances the function of the orofacial region, enhances sexual function, and also aids in coping with Raynaund's phenomenon, enhances physical capacity, alleviates fatigue as well and enhances general physical capacity. Furthermore, regular physical activity impeded the natural progression of progressive impairment of functional ability. Although, the literature regarding the efficacy and safety of exercise in patients with SSc is further insufficient.","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"58 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140964917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Russia's aggression against Ukraine is undoubtedly a tragic event that will bring various, often difficult to predict, consequences at many levels of functioning. Certainly, the mental health of war victims faces many challenges. The mental health crisis that occurs during war is a public health problem.28 One of the main disorders that appear in people directly or indirectly related to war is PTSD. It arises as a result of experiencing extremely dangerous, terrifying events that go beyond one's ability to cope and is manifested by symptoms such as: obsessive, persistent re-experiencing of traumatic events, avoidance of factors causing a "return" to traumatic memories, excessive arousal and a sense of constant threats.8, 10 Many factors influence the occurrence of PTSD. It is extremely important to look at the reasons that make it difficult to obtain support. mental health and improving the support system. Ukrainian children and youth deserve special attention here. A developing young society must face particularly great challenges, and it is their mental well-being that guarantees better development of the entire nation. Every effort must be made to ensure that citizens of a country at war receive adequate support. We have many methods of help, from basic emergency support, through a wide range of psychotherapy, to medications in the most severe cases. Additionally, the knowledge of the existence of a phenomenon such as post-traumatic growth may give hope and motivation to act to people in mental crisis struggling with symptoms of PTSD. However, the war continues and there will be more and more victims struggling with post-traumatic stress disorder (PTSD) and other mental health disorders. We cannot determine at this point how much damage this conflict will cause. However, it is worth acting now to prevent and limit the tragic consequences of the situation in which Ukraine finds itself.
{"title":"The war continues not only on the front: a broader look at PTSD in the context of the Russian invasion and its impact on Ukrainian citizens – systematic rewiev","authors":"Monika Adamczyk, Joanna Mazurek, Hubert Stachowicz, Magdalena Ptasznik, Aleksandra Baran, Weronika Bartos, Magdalena Piotrowska, Ewelina Flegiel, Justyna Lenart, Miłosz Podrażka","doi":"10.12775/jehs.2024.70.49961","DOIUrl":"https://doi.org/10.12775/jehs.2024.70.49961","url":null,"abstract":"Russia's aggression against Ukraine is undoubtedly a tragic event that will bring various, often difficult to predict, consequences at many levels of functioning. Certainly, the mental health of war victims faces many challenges. The mental health crisis that occurs during war is a public health problem.28 One of the main disorders that appear in people directly or indirectly related to war is PTSD. It arises as a result of experiencing extremely dangerous, terrifying events that go beyond one's ability to cope and is manifested by symptoms such as: obsessive, persistent re-experiencing of traumatic events, avoidance of factors causing a \"return\" to traumatic memories, excessive arousal and a sense of constant threats.8, 10 Many factors influence the occurrence of PTSD. It is extremely important to look at the reasons that make it difficult to obtain support. mental health and improving the support system. Ukrainian children and youth deserve special attention here. A developing young society must face particularly great challenges, and it is their mental well-being that guarantees better development of the entire nation. Every effort must be made to ensure that citizens of a country at war receive adequate support. We have many methods of help, from basic emergency support, through a wide range of psychotherapy, to medications in the most severe cases. Additionally, the knowledge of the existence of a phenomenon such as post-traumatic growth may give hope and motivation to act to people in mental crisis struggling with symptoms of PTSD. However, the war continues and there will be more and more victims struggling with post-traumatic stress disorder (PTSD) and other mental health disorders. We cannot determine at this point how much damage this conflict will cause. However, it is worth acting now to prevent and limit the tragic consequences of the situation in which Ukraine finds itself. \u0000 ","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"5 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140962546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-17DOI: 10.12775/jehs.2024.69.49174
Aldona Pażyra, Paweł Stanicki, Julita Szarpak, Natalia Kusak, Natalia Żak, Barbara Jaworska
In 2019, according to WHO estimates, 262 million people were affected by asta, resulting in 455,000 deaths. Asthma, is a chronic inflammatory disease of the airways that causes reversible bronchoconstriction, making it difficult for patients to breathe. Exacerbations of the disease can be caused by a variety of factors but share similar symptoms such as wheezing, coughing, shortness of breath and chest tightness. Severe asthma exacerbations are defined as symptoms that do not respond to inhaled medications and improve only after oral or intravenous steroid administration. Asthma-related deaths often occur during exacerbations. Vitamin D, which is produced naturally in the body and found in some foods, is a steroid-derived vitamin. Adequate doses of this vitamin, administered through medication or supplements, can be used to maintain its proper levels in the organism. Vitamin D is essential for regulating calcium levels in the body and for bone remodeling. It also has immunomodulatory effects, affecting both innate and adaptive immunity. This partly explains its association with changes in the airway epithelium that occur as a result of inflammation in asthma. The study aims to summarize the current knowledge on the relationship of vitamin D with asthma symptom control. The present study is based on literature available in scientific databases from 2013-2016, such as PubMed, Corchane Library and Google Scholar, using the following keywords: "vitamin D" and "asthma." Vitamin D deficiency is prevalent in children and adults worldwide. A critical analysis of the literature reveals that the therapeutic administration of vitamin D has no apparent advantage in treating asthma, especially in children. Nevertheless, for adults with mild asthma, vitamin D supplementation shows promise for improved outcomes. However, there is a pressing need for large-scale clinical trials to determine the efficacy and safety of this therapeutic approach for both age groups.
据世卫组织估计，2019年有2.62亿人受到哮喘的影响，导致45.5万人死亡。哮喘是一种慢性气道炎症性疾病，会导致可逆性支气管收缩，使患者呼吸困难。疾病加重可由多种因素引起，但症状相似，如喘息、咳嗽、气短和胸闷。严重的哮喘加重是指吸入药物无效，只有在口服或静脉注射类固醇后症状才会改善。与哮喘相关的死亡往往发生在哮喘恶化期间。维生素 D 是一种源自类固醇的维生素，可在人体内自然产生，并存在于某些食物中。通过药物或补充剂摄入足够剂量的这种维生素，可用于维持机体内的适当水平。维生素 D 对调节体内钙含量和骨骼重塑至关重要。它还具有免疫调节作用，对先天性免疫和适应性免疫都有影响。这在一定程度上解释了维生素 D 与哮喘炎症导致的气道上皮细胞变化之间的关系。本研究旨在总结维生素 D 与哮喘症状控制之间关系的现有知识。本研究以 2013-2016 年间在科学数据库（如 PubMed、Corchane Library 和 Google Scholar）中的文献为基础，使用了以下关键词："维生素 D "和 "哮喘"。维生素 D 缺乏症在全球儿童和成人中普遍存在。对文献的批判性分析表明，治疗性服用维生素 D 在治疗哮喘方面没有明显优势，尤其是对儿童而言。不过，对于患有轻度哮喘的成年人来说，补充维生素 D 有望改善治疗效果。然而，目前迫切需要进行大规模的临床试验，以确定这种治疗方法对这两个年龄组的疗效和安全性。
{"title":"Therapeutic Potential of Vitamin D in Asthma Control","authors":"Aldona Pażyra, Paweł Stanicki, Julita Szarpak, Natalia Kusak, Natalia Żak, Barbara Jaworska","doi":"10.12775/jehs.2024.69.49174","DOIUrl":"https://doi.org/10.12775/jehs.2024.69.49174","url":null,"abstract":"In 2019, according to WHO estimates, 262 million people were affected by asta, resulting in 455,000 deaths. Asthma, is a chronic inflammatory disease of the airways that causes reversible bronchoconstriction, making it difficult for patients to breathe. Exacerbations of the disease can be caused by a variety of factors but share similar symptoms such as wheezing, coughing, shortness of breath and chest tightness. Severe asthma exacerbations are defined as symptoms that do not respond to inhaled medications and improve only after oral or intravenous steroid administration. Asthma-related deaths often occur during exacerbations. Vitamin D, which is produced naturally in the body and found in some foods, is a steroid-derived vitamin. Adequate doses of this vitamin, administered through medication or supplements, can be used to maintain its proper levels in the organism. Vitamin D is essential for regulating calcium levels in the body and for bone remodeling. It also has immunomodulatory effects, affecting both innate and adaptive immunity. This partly explains its association with changes in the airway epithelium that occur as a result of inflammation in asthma. \u0000The study aims to summarize the current knowledge on the relationship of vitamin D with asthma symptom control. \u0000The present study is based on literature available in scientific databases from 2013-2016, such as PubMed, Corchane Library and Google Scholar, using the following keywords: \"vitamin D\" and \"asthma.\" \u0000Vitamin D deficiency is prevalent in children and adults worldwide. A critical analysis of the literature reveals that the therapeutic administration of vitamin D has no apparent advantage in treating asthma, especially in children. Nevertheless, for adults with mild asthma, vitamin D supplementation shows promise for improved outcomes. However, there is a pressing need for large-scale clinical trials to determine the efficacy and safety of this therapeutic approach for both age groups.","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"6 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140962662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-17DOI: 10.12775/jehs.2024.69.49390
Adela Sobolewska, Natalia Gierulska, Hubert Stachowicz, Kaja Iwaniuk, Zuzanna Białkowska, Aleksander Daniluk, Jan Ostański, Jakub Buczek, Maciej Samczuk, Łukasz Gawłowicz
In 2020, approximately 287,000 mothers died during pregnancy or childbirth, with one of the leading causes of maternal mortality being peripartum hemorrhage. It can be treated both pharmacologically and procedurally, for example, through uterine artery ligation, embolization, or hysterectomy. In case of procedural treatment, it is essential for the medical team to familiarize themselves with the anatomical structure of the patient's uterine arteries. Various variations in the course of this vessel are distinguished, such as the uterine artery branching as a bifurcation with the inferior gluteal artery, a common trunk of the uterine artery with another vessel, or even its duplication. Using radiological techniques such as angiography, it is possible to visualize vessels and their variations, which can allow for better patient care. Unfamiliarity with the departure and trajectory of the uterine artery may be associated with an increased risk of postoperative complications, especially after hysterectomy, where the uterine arteries close at the level of the uterus or at the beginning of their departure from the internal iliac artery. Ligating them in other place may result in ischemia of an area that should be continuously supplied with blood. Also, during surgery, special attention should be paid to possible anatomical variations of the patient's uterine artery, which, although rare, can cause intraoperative complications. A thorough analysis of the departure and trajectory of the uterine artery by physicians can prevent postoperative complications and also allow for the safe conduct of embolization procedures. The following article presents a literature review on the departure and course of the uterine artery and its variations, as well as procedural interventions related to this vessel.
{"title":"Variability of the origin and course of the uterine artery in clinical practice","authors":"Adela Sobolewska, Natalia Gierulska, Hubert Stachowicz, Kaja Iwaniuk, Zuzanna Białkowska, Aleksander Daniluk, Jan Ostański, Jakub Buczek, Maciej Samczuk, Łukasz Gawłowicz","doi":"10.12775/jehs.2024.69.49390","DOIUrl":"https://doi.org/10.12775/jehs.2024.69.49390","url":null,"abstract":"In 2020, approximately 287,000 mothers died during pregnancy or childbirth, with one of the leading causes of maternal mortality being peripartum hemorrhage. It can be treated both pharmacologically and procedurally, for example, through uterine artery ligation, embolization, or hysterectomy. In case of procedural treatment, it is essential for the medical team to familiarize themselves with the anatomical structure of the patient's uterine arteries. Various variations in the course of this vessel are distinguished, such as the uterine artery branching as a bifurcation with the inferior gluteal artery, a common trunk of the uterine artery with another vessel, or even its duplication. Using radiological techniques such as angiography, it is possible to visualize vessels and their variations, which can allow for better patient care. Unfamiliarity with the departure and trajectory of the uterine artery may be associated with an increased risk of postoperative complications, especially after hysterectomy, where the uterine arteries close at the level of the uterus or at the beginning of their departure from the internal iliac artery. Ligating them in other place may result in ischemia of an area that should be continuously supplied with blood. Also, during surgery, special attention should be paid to possible anatomical variations of the patient's uterine artery, which, although rare, can cause intraoperative complications. A thorough analysis of the departure and trajectory of the uterine artery by physicians can prevent postoperative complications and also allow for the safe conduct of embolization procedures. The following article presents a literature review on the departure and course of the uterine artery and its variations, as well as procedural interventions related to this vessel.","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"92 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140963999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-17DOI: 10.12775/jehs.2024.69.49393
K. Rachwał, Karol Wielgus, Piotr Bator, Wiktor Razik, Grzegorz Łyko, Maria Antos, Julia Furgalska, Maria Pawłowska, A. Wawryszuk
Introduction and purpose: Lactose, the primary carbohydrate in milk, requires the enzyme lactase for digestion. Deficiency in lactase activity leads to lactose intolerance, causing gastrointestinal symptoms. Understanding the genetic and environmental factors influencing lactase expression and activity is crucial. Moreover, accurate diagnostic methods and effective treatments are needed to manage lactose intolerance. This review aims to explore the current knowledge on lactase deficiency, lactose intolerance, diagnostic methods, and treatment options. State of knowledge: Lactase deficiency encompasses congenital, primary, and secondary forms, each with distinct etiologies. Although often used interchangeably, lactase deficiency and lactose intolerance differ. However, the association between lactase deficiency and lactose intolerance is complex, influenced by various factors including dietary habits, gut microbiota, and gastrointestinal motility. Diagnostic methods are limited, and treatment strategies primarily involve dietary modifications, lactase supplementation, and probiotics. Conclusion: Lactose intolerance presents significant clinical challenges, often underrecognized and misdiagnosed. Despite diagnostic advancements further research is needed to refine diagnostic accuracy. Treatment focuses on dietary adjustments, enzyme supplementation, and probiotics. Balancing symptom relief with nutritional adequacy is essential. Future studies should explore the role of gut microbiome modulation in lactose intolerance management through clinical trials.
{"title":"Lactase Deficiency and Lactose Intolerance: Current Understanding and Future Directions","authors":"K. Rachwał, Karol Wielgus, Piotr Bator, Wiktor Razik, Grzegorz Łyko, Maria Antos, Julia Furgalska, Maria Pawłowska, A. Wawryszuk","doi":"10.12775/jehs.2024.69.49393","DOIUrl":"https://doi.org/10.12775/jehs.2024.69.49393","url":null,"abstract":"Introduction and purpose: Lactose, the primary carbohydrate in milk, requires the enzyme lactase for digestion. Deficiency in lactase activity leads to lactose intolerance, causing gastrointestinal symptoms. Understanding the genetic and environmental factors influencing lactase expression and activity is crucial. Moreover, accurate diagnostic methods and effective treatments are needed to manage lactose intolerance. This review aims to explore the current knowledge on lactase deficiency, lactose intolerance, diagnostic methods, and treatment options. State of knowledge: Lactase deficiency encompasses congenital, primary, and secondary forms, each with distinct etiologies. Although often used interchangeably, lactase deficiency and lactose intolerance differ. However, the association between lactase deficiency and lactose intolerance is complex, influenced by various factors including dietary habits, gut microbiota, and gastrointestinal motility. Diagnostic methods are limited, and treatment strategies primarily involve dietary modifications, lactase supplementation, and probiotics. Conclusion: Lactose intolerance presents significant clinical challenges, often underrecognized and misdiagnosed. Despite diagnostic advancements further research is needed to refine diagnostic accuracy. Treatment focuses on dietary adjustments, enzyme supplementation, and probiotics. Balancing symptom relief with nutritional adequacy is essential. Future studies should explore the role of gut microbiome modulation in lactose intolerance management through clinical trials. ","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"113 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141126507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Folliculitis decalvans (FD) is a rare subtype of neutrophilic cicatricial alopecia, firstly described by Quinquad in 1888, as inflammatory scalp disease usually affecting young adults. The exact etiopathology of the disease is not fully understood, however the presence of Staphylococcus aureus, dysfunction of the host’s immune response, genetic factors, previous trauma of the scalp, as well as Epidermal Growth Factor Receptor inhibitors (EGFRi) use seem to play a role. Clinically, FD presents with scarring alopecic patches with follicular pustules, crusts and tufted hair. Objectives: As the full etiology of the disease is unknown and most data in the literature is based on retrospective date, therapeutic management is not precisely established. The objective of this review is to describe therapeutic options, as well as highlighting potential new therapeutic modalities reported in the literature. Limitations: Because FD is a rare disease, the main limitation is lack of randomized control trials, evaluating therapeutic modalities. Methods: An exhaustive search of references related to FD published in PubMed between 2017 and 2024 was undertaken, using the search term: "folliculitis decalvans". Articles with large patient cohorts and reviews were included, as well as case reports and case series, that reported novel treatment approaches for FD.Conclusions: The management of FD poses a challenge. Systemic antibiotics, particularly rifampicin and clindamycin, are considered the first-line agents and are commonly used in combination with local therapies. Systemic isotretinoin yields sustained remission in some cases, while biological agents exhibit promise in managing severe FD. Novel therapeutic modalities, incorporating, among others, botulinum toxin A injections, Platelet-Rich-Plasma (PRP), or surgical procedures, necessitate randomized double-blind trials to evaluate their safety and efficacy.
背景：德加尔万毛囊炎（FD）是嗜中性卡他性脱发的一种罕见亚型，由Quinquad于1888年首次描述，是一种炎症性头皮疾病，通常影响青壮年。该病的确切病因尚未完全明了，但金黄色葡萄球菌的存在、宿主免疫反应功能障碍、遗传因素、头皮曾受创伤以及表皮生长因子受体抑制剂（EGFRi）的使用似乎在其中发挥了作用。在临床上，FD 表现为带有毛囊脓疱、结痂和丛生头发的瘢痕性脱发斑。研究目的由于该病的病因尚不清楚，且文献中的大多数数据都是基于回顾性数据，因此治疗方法尚未精确确定。本综述旨在描述治疗方案，并重点介绍文献中报道的潜在新治疗方法。局限性：由于 FD 是一种罕见疾病，其主要局限性在于缺乏评估治疗方法的随机对照试验。研究方法使用检索词对2017年至2024年间发表在PubMed上的与FD相关的参考文献进行了详尽检索："decalvans毛囊炎"。 纳入了大量患者群和综述的文章，以及报道FD新型治疗方法的病例报告和系列病例：结论：FD 的治疗是一项挑战。全身用抗生素，尤其是利福平和林可霉素，被认为是一线药物，通常与局部疗法联合使用。在某些病例中，全身使用异维A酸可获得持续缓解，而生物制剂则有望治疗严重的 FD。新的治疗方法包括注射 A 型肉毒毒素、血小板丰富血浆（PRP）或外科手术等，需要进行随机双盲试验以评估其安全性和有效性。
{"title":"Folliculitis Decalvans: A Review of Current Treatment Modalities","authors":"Wiktoria Julia Krzesłowska, Kamila Szewczyk, Paulina Pytel, Bartłomiej Szewczyk, Szymon Wiśniewski, Weronika Hołownia","doi":"10.12775/jehs.2024.70.50172","DOIUrl":"https://doi.org/10.12775/jehs.2024.70.50172","url":null,"abstract":"Background: Folliculitis decalvans (FD) is a rare subtype of neutrophilic cicatricial alopecia, firstly described by Quinquad in 1888, as inflammatory scalp disease usually affecting young adults. The exact etiopathology of the disease is not fully understood, however the presence of Staphylococcus aureus, dysfunction of the host’s immune response, genetic factors, previous trauma of the scalp, as well as Epidermal Growth Factor Receptor inhibitors (EGFRi) use seem to play a role. Clinically, FD presents with scarring alopecic patches with follicular pustules, crusts and tufted hair. Objectives: As the full etiology of the disease is unknown and most data in the literature is based on retrospective date, therapeutic management is not precisely established. The objective of this review is to describe therapeutic options, as well as highlighting potential new therapeutic modalities reported in the literature. Limitations: Because FD is a rare disease, the main limitation is lack of randomized control trials, evaluating therapeutic modalities. Methods: An exhaustive search of references related to FD published in PubMed between 2017 and 2024 was undertaken, using the search term: \"folliculitis decalvans\". Articles with large patient cohorts and reviews were included, as well as case reports and case series, that reported novel treatment approaches for FD.Conclusions: The management of FD poses a challenge. Systemic antibiotics, particularly rifampicin and clindamycin, are considered the first-line agents and are commonly used in combination with local therapies. Systemic isotretinoin yields sustained remission in some cases, while biological agents exhibit promise in managing severe FD. Novel therapeutic modalities, incorporating, among others, botulinum toxin A injections, Platelet-Rich-Plasma (PRP), or surgical procedures, necessitate randomized double-blind trials to evaluate their safety and efficacy.","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"52 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140964948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-17DOI: 10.12775/jehs.2024.70.49557
Klaudia Kułak, Izabela Sztybór, Katarzyna Kamińska
Introduction and purpose: The article deals with the problem of obesity, which significantly increases the number of cases among children, adolescents and adults all over the world, leading to the occurrence of systemic disorders. A noticeable increase in the incidence of atherosclerosis, metabolic syndrome and diabetes leads to a reduction in life expectancy. The main aim of the work is to emphasize the seriousness of the contemporary problem, which causes impairment of the functioning of many systems. A secondary goal is to indicate the current standards of obesity treatment and how to deal with overweight. Brief description of the state of knowledge: Obesity is a disease that affects nearly 800 million people around the world and affects every fourth Pole. Uncontrolled weight gain is caused; lifestyle changes, consumption of highly processed foods, and genetic and endocrine factors. It is a chronic disease with a tendency to relapse, with serious consequences and in need of diagnostics, personalized treatment, and often associated with psychological support. Material and methods: The article analyzes the research to date and the latest treatment methods, which show that a person struggling with obesity is at risk of over 200 complications, including, for example, fatty liver, stroke, type 2 diabetes or cancer. Results and conclusion: According to our analysis, obesity is a pathological condition that is truly life-threatening. Despite the society's downplay of the problem, people affected by this disease struggle with many comorbidities that worsen their quality of life.
{"title":"Obesity - an epidemic of the 21st century – literature review","authors":"Klaudia Kułak, Izabela Sztybór, Katarzyna Kamińska","doi":"10.12775/jehs.2024.70.49557","DOIUrl":"https://doi.org/10.12775/jehs.2024.70.49557","url":null,"abstract":"Introduction and purpose: The article deals with the problem of obesity, which significantly increases the number of cases among children, adolescents and adults all over the world, leading to the occurrence of systemic disorders. A noticeable increase in the incidence of atherosclerosis, metabolic syndrome and diabetes leads to a reduction in life expectancy. The main aim of the work is to emphasize the seriousness of the contemporary problem, which causes impairment of the functioning of many systems. A secondary goal is to indicate the current standards of obesity treatment and how to deal with overweight. \u0000 \u0000Brief description of the state of knowledge: Obesity is a disease that affects nearly 800 million people around the world and affects every fourth Pole. Uncontrolled weight gain is caused; lifestyle changes, consumption of highly processed foods, and genetic and endocrine factors. It is a chronic disease with a tendency to relapse, with serious consequences and in need of diagnostics, personalized treatment, and often associated with psychological support. \u0000 \u0000Material and methods: The article analyzes the research to date and the latest treatment methods, which show that a person struggling with obesity is at risk of over 200 complications, including, for example, fatty liver, stroke, type 2 diabetes or cancer. \u0000 \u0000Results and conclusion: According to our analysis, obesity is a pathological condition that is truly life-threatening. Despite the society's downplay of the problem, people affected by this disease struggle with many comorbidities that worsen their quality of life.","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"6 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140962506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-17DOI: 10.12775/jehs.2024.70.50183
Zuzanna Kotowicz, Aleksandra Pich-Czekierda, Patrycja Proszowska, Adrianna Orzeł, Daria Sieniawska, Magda Madoń, Julia Sieniawska
IntroductionCollagen is a protein that has found widespread use both as an ingredient in cosmetics applied externally and as an oral supplement. This substance is obtained from a number of animal sources, including bovine tissues, as well as marine fish. The characteristic properties of collagen peptides, such as scientifically proven anti-inflammatory effects, activation of fibroblast skin cells, stimulation of synovial cells to produce hyaluronic acid, and much more make this type of supplement promising in improving the body's general condition and in alleviating the symptoms of many ailments. Numerous scientific studies have shown that supplementation with hydrolyzed collagen has a beneficial effect on both the overall condition of the skin by improving its elasticity, hydration level, and positive action on its protective barrier and on the musculoskeletal system, where, when combined with appropriately selected physical activity, it can help to reduce pain associated with conditions such as osteoarthritis and even increase the range of movement in the joints. Easy availability, user-friendly forms of administration, such as powders or ready-to-drink liquid formulations, and a low incidence of side effects make this supplementation highly beneficial for users. Aim of the studyThis study aims to discuss the known processes and review the evidence supporting the beneficial effects of hydrolyzed collagen supplementation on the human skin and musculoskeletal system.Material and methodThis article presents the current state of knowledge about the benefits of oral collagen peptide supplementation in various scientific articles. Publications describing the mechanisms of action and the effects of collagen supplementation on skin conditions and the musculoskeletal system, including recent reports in this field, were reviewed using the PubMed platform. The search included the keywords ‘collagen’, ‘collagen supplementation’, ‘nutritional supplement’, ‘recovery’
{"title":"Advantages of oral collagen supplementation. Review of the literature","authors":"Zuzanna Kotowicz, Aleksandra Pich-Czekierda, Patrycja Proszowska, Adrianna Orzeł, Daria Sieniawska, Magda Madoń, Julia Sieniawska","doi":"10.12775/jehs.2024.70.50183","DOIUrl":"https://doi.org/10.12775/jehs.2024.70.50183","url":null,"abstract":"IntroductionCollagen is a protein that has found widespread use both as an ingredient in cosmetics applied externally and as an oral supplement. This substance is obtained from a number of animal sources, including bovine tissues, as well as marine fish. The characteristic properties of collagen peptides, such as scientifically proven anti-inflammatory effects, activation of fibroblast skin cells, stimulation of synovial cells to produce hyaluronic acid, and much more make this type of supplement promising in improving the body's general condition and in alleviating the symptoms of many ailments. Numerous scientific studies have shown that supplementation with hydrolyzed collagen has a beneficial effect on both the overall condition of the skin by improving its elasticity, hydration level, and positive action on its protective barrier and on the musculoskeletal system, where, when combined with appropriately selected physical activity, it can help to reduce pain associated with conditions such as osteoarthritis and even increase the range of movement in the joints. Easy availability, user-friendly forms of administration, such as powders or ready-to-drink liquid formulations, and a low incidence of side effects make this supplementation highly beneficial for users. Aim of the studyThis study aims to discuss the known processes and review the evidence supporting the beneficial effects of hydrolyzed collagen supplementation on the human skin and musculoskeletal system.Material and methodThis article presents the current state of knowledge about the benefits of oral collagen peptide supplementation in various scientific articles. Publications describing the mechanisms of action and the effects of collagen supplementation on skin conditions and the musculoskeletal system, including recent reports in this field, were reviewed using the PubMed platform. The search included the keywords ‘collagen’, ‘collagen supplementation’, ‘nutritional supplement’, ‘recovery’","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"62 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140965017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-17DOI: 10.12775/jehs.2024.70.49529
Anna Szymkowicz, Julia Pałuchowska, Maria Sambura, Sara Rosołowska-Żak, Patrycja Paschke, Igor Miczek
Introduction: Diagnosis of choledocholithiasis, a common manifestation of gallstone disease, is mainly based on advanced endoscopic techniques such as ERCP and EUS. Since the 1970s, ERCP has been a key method in the diagnosis and treatment of choledocholithiasis, allowing direct visualization and therapeutic interventions. However, technological developments have brought the emergence of EUS as a complementary tool, providing high-resolution imaging of the bile ducts. Understanding the diagnostic accuracy, therapeutic options and complications of both modalities is key to optimizing the care of patients with bile duct stones. Aim of the study: The aim of our study is to review and compare various diagnostic methods of bile duct stones, as well as to assess their effectiveness, accuracy, and potential complications. Materials and methods: We searched electronic sources, aspecially in the PubMed and Google Scholar databases, using keywords such as ,,endoscopic ultrasonography”, ,,endoscopic retrograde cholangiopancreatography” and ,,choledocholithiasis”. Conclusions: With the use of modern technologies, such as endoscopic ultrasonography (EUS) and retrograde choleangiopancreatography (ERCP), it has become possible to diagnose bile duct stones more accurately and introduce more effective and less invasive therapies. The development of the availability of diagnostic tests, especially those that do not require invasive procedures, has helped reduce the risk of complications. EUS may be the preferred tool of choice for patients with gallstones, as it is associated with a lower risk of complications compared to ERCP alone. Decisions regarding the use of specific diagnostic and therapeutic modalities should be made on a case-by-case basis, taking into account medical and economic considerations.
{"title":"ERCP (endoscopic retrograde cholangiopancreatography) and EUS (endoscopic ultrasonography) in diagnosis of choledocholithiasis – battle or cooperation?","authors":"Anna Szymkowicz, Julia Pałuchowska, Maria Sambura, Sara Rosołowska-Żak, Patrycja Paschke, Igor Miczek","doi":"10.12775/jehs.2024.70.49529","DOIUrl":"https://doi.org/10.12775/jehs.2024.70.49529","url":null,"abstract":"Introduction: Diagnosis of choledocholithiasis, a common manifestation of gallstone disease, is mainly based on advanced endoscopic techniques such as ERCP and EUS. Since the 1970s, ERCP has been a key method in the diagnosis and treatment of choledocholithiasis, allowing direct visualization and therapeutic interventions. However, technological developments have brought the emergence of EUS as a complementary tool, providing high-resolution imaging of the bile ducts. Understanding the diagnostic accuracy, therapeutic options and complications of both modalities is key to optimizing the care of patients with bile duct stones. \u0000Aim of the study: The aim of our study is to review and compare various diagnostic methods of bile duct stones, as well as to assess their effectiveness, accuracy, and potential complications. \u0000Materials and methods: We searched electronic sources, aspecially in the PubMed and Google Scholar databases, using keywords such as ,,endoscopic ultrasonography”, ,,endoscopic retrograde cholangiopancreatography” and ,,choledocholithiasis”. \u0000Conclusions: With the use of modern technologies, such as endoscopic ultrasonography (EUS) and retrograde choleangiopancreatography (ERCP), it has become possible to diagnose bile duct stones more accurately and introduce more effective and less invasive therapies. The development of the availability of diagnostic tests, especially those that do not require invasive procedures, has helped reduce the risk of complications. EUS may be the preferred tool of choice for patients with gallstones, as it is associated with a lower risk of complications compared to ERCP alone. Decisions regarding the use of specific diagnostic and therapeutic modalities should be made on a case-by-case basis, taking into account medical and economic considerations.","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140962487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-17DOI: 10.12775/jehs.2024.70.51094
Katarzyna Burda, Karolina Czarnecka, Olga Łopacińska, Katarzyna Stańczyk, Aleksandra Korn, Emilia Wójcik, Anna Korczak, Justyna Jędrzejczyk, Oliwia Szewczyk, Ewa Olek
Introduction: Herbal medicine has been growing in popularity over the last few years. One of the most often used herbal remedy is Withania somnifera, more widely known as Ashwagandha Now known for its anti-stress, anti-inflammatory, antioxidant, anti-cancer, anti-anxiety properties it ranks as a cure-all. However, there is a rising amount of alarming reports regarding its safety. It has been observed that its effects are not always beneficial, and for some patients the risks of taking it may be greater than the promoted benefits. Aim of study: The aim of this paper is to evaluate possible risks connected to Withania Somnifera consumption based on available research articles and case reports. Materials and methods: This article is based on the literature found in the PubMed Database from the period of 2004-2024 with the use of keywords such as “Ashwagandha”; “Withania Somnifera”, “herbal medicine”;”complementary medicine”;“liver injury”; “thyrotoxicosis”; “adrenal insufficiency”;”autoimmune diseases”. Results: The outcomes of all the reviewed studies in this paper indicate that Withania Somnifera might cause a wide range of side effects. They include herb induced liver injury, endocrine complications such as thyrotoxicosis and adrenal insufficiency, acute graft rejection in a kidney transplant recipient and possible contribution to the onset of new autoimmune disease in patient with the history of autoimmune disorders. Conclusion: Further long-term research is needed on the Ashwaghanda’s benefits but particularly on its safety and potential side effects. The common education on the risks of taking herbal supplements should be carried out among health professionals and the rest of the society. Ashwagandha should not be used by patients with liver, endocrine and autoimmune disorders as well as transplant recipients.
{"title":"The dark side of herbal medicine - risks of Ashwagandha (Withania Somnifera) consumption","authors":"Katarzyna Burda, Karolina Czarnecka, Olga Łopacińska, Katarzyna Stańczyk, Aleksandra Korn, Emilia Wójcik, Anna Korczak, Justyna Jędrzejczyk, Oliwia Szewczyk, Ewa Olek","doi":"10.12775/jehs.2024.70.51094","DOIUrl":"https://doi.org/10.12775/jehs.2024.70.51094","url":null,"abstract":"Introduction: Herbal medicine has been growing in popularity over the last few years. One of the most often used herbal remedy is Withania somnifera, more widely known as Ashwagandha Now known for its anti-stress, anti-inflammatory, antioxidant, anti-cancer, anti-anxiety properties it ranks as a cure-all. However, there is a rising amount of alarming reports regarding its safety.\u0000It has been observed that its effects are not always beneficial, and for some patients the risks of taking it may be greater than the promoted benefits. \u0000Aim of study: The aim of this paper is to evaluate possible risks connected to Withania Somnifera consumption based on available research articles and case reports. \u0000Materials and methods: This article is based on the literature found in the PubMed Database from the period of 2004-2024 with the use of keywords such as “Ashwagandha”; “Withania Somnifera”, “herbal medicine”;”complementary medicine”;“liver injury”; “thyrotoxicosis”; “adrenal insufficiency”;”autoimmune diseases”.\u0000Results: The outcomes of all the reviewed studies in this paper indicate that Withania Somnifera might cause a wide range of side effects. They include herb induced liver injury, endocrine complications such as thyrotoxicosis and adrenal insufficiency, acute graft rejection in a kidney transplant recipient and possible contribution to the onset of new autoimmune disease in patient with the history of autoimmune disorders. \u0000Conclusion: Further long-term research is needed on the Ashwaghanda’s benefits but particularly on its safety and potential side effects. The common education on the risks of taking herbal supplements should be carried out among health professionals and the rest of the society. Ashwagandha should not be used by patients with liver, endocrine and autoimmune disorders as well as transplant recipients.","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"45 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140965928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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