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Long-term Effects of Iron Deficiency in Early Infancy on Neurodevelopment 婴儿早期缺铁对神经发育的长期影响
Pub Date : 2024-05-17 DOI: 10.12775/jehs.2024.70.51104
Anna Korczak, Emilia Wójcik, Ewa Olek, Olga Łopacińska, Katarzyna Stańczyk, Aleksandra Korn, Justyna Jędrzejczyk, Oliwia Szewczyk, Katarzyna Burda, Karolina Czarnecka
Introduction and  Purpose: Iron deficiency alongside anaemia is one of the most significant global health concerns with potentially long-lasting implications on child development and health outcomes. The period of infancy represents a crucial phase of central nervous system maturation, rendering infants particularly susceptible to the adverse effects of iron deficiency. It is therefore crucial to pay close attention to this issue.  The aim of this review is to elucidate the neurological implications of iron deficiency in infancy and emphasize the necessity of implementing preventive strategies to safeguard child development. State  of  Knowledge: Iron deficiency in infancy can result in impairments of brain development. Extensive research highlights the influence of this micronutrient on various physiological processes, including the synthesis of neurotransmitters, neuronal metabolism, myelination, synaptogenesis and gene expression. Furthermore, iron deficiency during infancy is associated with adverse developmental outcomes, including cognitive, motor, and socioemotional deficits. Long-term follow-up studies have elucidated the enduring neurological consequences of iron deficiency in infancy, with effects extending into childhood and beyond. Summary: Given that the changes that occur during the infantile period are often irreversible and have long-lasting implications for future development, it is of the utmost importance to prioritize prevention strategies.
引言和目的:缺铁和贫血是全球最重要的健康问题之一,可能会对儿童发育和健康结果产生长期影响。婴儿期是中枢神经系统成熟的关键时期,因此特别容易受到缺铁的不良影响。因此,密切关注这一问题至关重要。 本综述旨在阐明婴儿期缺铁对神经系统的影响,并强调实施预防策略以保障儿童发育的必要性。知识现状:婴儿期缺铁会导致大脑发育障碍。大量研究表明,这种微量元素对各种生理过程都有影响,包括神经递质的合成、神经元代谢、髓鞘化、突触生成和基因表达。此外,婴儿期缺铁与不良发育结果有关,包括认知、运动和社会情感缺陷。长期跟踪研究阐明了婴儿期缺铁对神经系统的持久影响,这种影响会延续到儿童期及以后。小结:鉴于婴儿期发生的变化往往是不可逆的,并对未来的发展产生长期影响,因此优先采取预防策略至关重要。
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引用次数: 0
Strategies for Treating Acute Migraines and Identifying Triggers. Literature review 治疗急性偏头痛和识别诱发因素的策略。文献综述
Pub Date : 2024-05-17 DOI: 10.12775/jehs.2024.69.49179
Zuzanna Kotowicz, Jakub Pabiś, Piotr Podgórski, Sandra Górecka, Miłosz Olszański, Aleksander Bogusz, Oskar Kwiatkowski, Anna Kołodziej, Anita Król
IntroductionMigraine, a prevalent neurological disorder affecting a substantial portion of the global population, poses a significant burden on individuals' overall quality of life. While the exact pathophysiological mechanisms underlying migraine headache attacks remain elusive, the involvement of trigeminal pathway activation is well-documented. A multitude of factors, collectively termed triggers, have been identified as capable of precipitating migraine episodes, ranging from dietary components to environmental stimuli such as bright lights and weather fluctuations. Migraine headaches typically manifest as throbbing pain localized predominantly on one side of the head and are often accompanied by a constellation of additional symptoms including photophobia, phonophobia, and nausea. The management of migraine involves a diverse array of therapeutic modalities tailored to the specific characteristics of the pain experienced. These may include the administration of non-steroidal anti-inflammatory drugs (NSAIDs), paracetamol, triptans, and antiemetics, among others. This study endeavors to explore the most prevalent triggers implicated in migraine onset, as well as contemporary treatment strategies, with an emphasis on incorporating the latest research findings and therapeutic advancements in this evolving field.Aim of the studyThis review aims to identify symptoms, triggers of acute migraine and solutions in its treatment process, including latest developments.Material and methodThis article presents the current state of knowledge about acute migraine, triggers and treatment options in various scientific articles. Publications describing acute migraine attacks and treatments including the most recent reports in the field were reviewed using the PubMed platform. The search included the keywords ‘migraine, 'migraine triggers', 'triptans', 'migraine with aura'.
导言:偏头痛是一种普遍存在的神经系统疾病,影响着全球相当一部分人口,对个人的整体生活质量造成了沉重负担。虽然偏头痛发作的确切病理生理机制仍难以捉摸,但三叉神经通路激活的参与已得到充分证实。已发现多种因素(统称为诱发因素)可诱发偏头痛发作,包括饮食成分、环境刺激(如强光和天气波动)等。偏头痛通常表现为主要位于头部一侧的搏动性疼痛,并经常伴有一系列其他症状,包括畏光、畏声和恶心。偏头痛的治疗需要根据疼痛的具体特点采取多种治疗方法。其中可能包括使用非甾体抗炎药(NSAIDs)、扑热息痛、曲坦类药物和止吐药等。本研究旨在探讨偏头痛发病中最常见的诱发因素以及当代治疗策略,重点是将最新的研究成果和治疗进展纳入这一不断发展的领域。文章使用 PubMed 平台对描述急性偏头痛发作和治疗方法的文献(包括该领域的最新报告)进行了审查。搜索关键词包括 "偏头痛"、"偏头痛诱因"、"三苯氧胺"、"有先兆的偏头痛"。
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引用次数: 0
Alcoholic Cardiomyopathy: a summary of current knowledge and possible future directions 酒精性心肌病:现有知识概述和未来可能的发展方向
Pub Date : 2024-05-17 DOI: 10.12775/jehs.2024.69.49619
Aleksander Górny, Anna Wójcik, Justyna Chwiejczak, Michał Obrębski, Jan Kościan, Julita Młynarska, Jakub Langa, Karolina Szczerkowska, Anna Seroka, Maria Rybicka
Introduction and purpose:  Ethanol is still one of the most frequently consumed drugs worldwide and is a strong risk factor for more than 60 illnesses including alcoholic cardiomyopathy which is a specific heart muscle disease caused by long-term excessive alcohol consumption. The review aims to gather available data and summarize it to give better understanding of the disease, to help select patients with the condition to implement proper treatment, and to present possible future directions as the incidence of the disease is projected to persist in the future.  Brief description of the state of knowledge:  Alcoholic cardiomyopathy (ACM) is characterized by dilation, increased mass of the left ventricle, and reduced ejection fraction leading to end-stage heart failure. It is caused by ethanol’s direct toxicity on myocytes disturbing many different metabolic pathways. The result is a decrease in both systolic and diastolic function of the heart. The ACM development depends on factors such as genetics, gender, dietary factors and the dosage of ethanol consumption. The goal of the treatment is total alcohol abstinence, but  the reduction of ethanol intake may also be beneficial. Patients  should obtain a complete pharmacological treatment for heart failure. Summary: Ethanol overconsumption remains an unresolved problem, with the incidence of ACM projected to persist in the future, especially among patients with alcohol use disorder (AUD). Efforts for prevention, early detection, and effective treatment of ACM need to be established. A primary focus should be on treating AUD because it is the most effective way to halt the progression of the disease. Further research should focus on both asymptomatic and symptomatic patients with AUD to better define clinical manifestations, diagnostic approaches, and the most effective treatments for ACM.
导言和目的:乙醇仍是全球最常消费的药物之一,也是60多种疾病的高危因素,其中包括酒精性心肌病,这是一种因长期过量饮酒而导致的特殊心肌疾病。本综述旨在收集现有数据并进行总结,以便更好地了解该疾病,帮助选择患有该疾病的患者以实施适当的治疗,并提出未来可能的发展方向,因为预计该疾病的发病率在未来仍将持续。 知识现状简介: 酒精性心肌病(ACM)的特征是左心室扩张、质量增加和射血分数降低,从而导致终末期心力衰竭。它是由于乙醇对心肌细胞的直接毒性扰乱了许多不同的代谢途径。其结果是心脏收缩和舒张功能下降。ACM 的发病取决于遗传、性别、饮食因素和乙醇摄入量等因素。治疗的目标是完全戒酒,但减少乙醇摄入量也可能有益。患者应接受全面的心力衰竭药物治疗。小结:乙醇摄入过量仍是一个尚未解决的问题,预计 ACM 的发病率在未来仍将持续,尤其是在酒精使用障碍(AUD)患者中。需要努力预防、早期发现和有效治疗 ACM。首要重点应放在治疗 AUD 上,因为这是阻止病情发展的最有效方法。进一步的研究应侧重于无症状和有症状的 AUD 患者,以更好地确定 ACM 的临床表现、诊断方法和最有效的治疗方法。
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引用次数: 0
Significance of the Gut-Brain Axis in the Development of Overweight and Obesity 肠道-大脑轴在超重和肥胖症发展过程中的意义
Pub Date : 2024-05-17 DOI: 10.12775/jehs.2024.70.49434
Martyna Kuśmierska, Jakub Kuśmierski, Izabela Janik, Anna Martyka, Przemysław Ujma
Introduction: The global obesity crisis results from inactive lifestyles and poor diets, increasing the risk of metabolic disorders. Emerging research links obesity with gut microbiome changes influenced by factors like age, genetics, and diet. Gut-brain communication via neural, endocrine, and inflammatory pathways, influenced by microbial compounds, affects nervous system function.Materials and Methods of Research: A thorough literature review was performed using PubMed and Google Scholar, employing keywords related to the gut-brain axis and obesity.Results: Obesity shifts gut microbiota composition due to factors like childbirth method, diet, antibiotics, and environment. This imbalance impacts metabolism, appetite, and insulin sensitivity. Gut microbes influence the brain, regulating energy balance and inflammation. Dysregulated tryptophan metabolism leads to insulin resistance. Gut-brain communication via the vagal nerve affects nutrient metabolism. Hormones like insulin and leptin, along with microbial metabolites, affect lipid metabolism and appetite. Gut microbiota abundance correlates with leptin signaling, and changes in ghrelin levels relate to microbiota composition. Microbial presence affects food cravings. Inflammation in obesity is linked to gut microbiota changes, mediated by bile acids and microbial metabolites. Interventions like probiotics and fecal microbiota transplantation offer potential for managing obesity. Emerging therapies like peptide D3 hold promise but require further study.Conclusion: The microbiome-gut-brain axis is vital in obesity, affecting metabolism, inflammation, and appetite. Utilizing interventions such as dietary adjustments and probiotics targeting gut-brain signaling shows promise in managing obesity. Personalized approaches are crucial due to microbiome complexity. Further research is needed to develop effective therapies for the obesity epidemic.
引言不活跃的生活方式和不良的饮食习惯导致全球肥胖危机,增加了代谢紊乱的风险。新的研究将肥胖与受年龄、遗传和饮食等因素影响的肠道微生物组变化联系起来。肠道与大脑之间通过神经、内分泌和炎症途径进行的交流受到微生物化合物的影响,从而影响神经系统的功能:使用 PubMed 和 Google Scholar 进行了全面的文献综述,并使用了与肠道-大脑轴和肥胖相关的关键词:肥胖会改变肠道微生物群的组成,这是由分娩方式、饮食、抗生素和环境等因素造成的。这种失衡会影响新陈代谢、食欲和胰岛素敏感性。肠道微生物影响大脑,调节能量平衡和炎症。色氨酸代谢失调会导致胰岛素抵抗。肠道通过迷走神经与大脑沟通,影响营养代谢。胰岛素和瘦素等激素以及微生物代谢产物会影响脂质代谢和食欲。肠道微生物群的丰度与瘦素信号相关,胃泌素水平的变化与微生物群的组成有关。微生物的存在会影响对食物的渴望。肥胖症的炎症与肠道微生物群的变化有关,由胆汁酸和微生物代谢产物介导。益生菌和粪便微生物群移植等干预措施为控制肥胖提供了可能。多肽 D3 等新兴疗法前景广阔,但还需要进一步研究:微生物组-肠-脑轴对肥胖至关重要,会影响新陈代谢、炎症和食欲。利用饮食调整和益生菌等针对肠脑信号转导的干预措施有望控制肥胖。由于微生物组的复杂性,个性化方法至关重要。要开发出治疗肥胖症的有效疗法,还需要进一步的研究。
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引用次数: 0
Biological treatment options for severe asthma in Poland 波兰重症哮喘的生物治疗方案
Pub Date : 2024-05-17 DOI: 10.12775/jehs.2024.70.51135
Maciej Superson, Klaudia Wilk-Trytko, Katarzyna Szmyt, Sylwia Samojedny, Katarzyna Szymańska, Kamil Walczak, Julia Krasnoborska, Julia Zarębska
Intruduction and purpose: Patients with severe asthma account for approximately 3% to 10% of all asthma patients. They have higher hospital utilization rates and treatment costs than patients with non-severe asthma. Previously, treatment options for these patients were limited due to unacceptable side effects. However, the advent of biologic therapies has provided promising targeted therapy for these patients. State of knowledge: Biologic therapies target inflammatory modulators that play a key role in the pathogenesis of asthma, particularly in patients with high T2 cells. These therapies have shown promising results in reducing asthma symptoms, improving lung function, decreasing the use of oral corticosteroids, and enhancing patients' quality of life. Conclusions: This article reviews the mechanism of action, efficacy, and indications of currently approved biologic drugs available in Poland, as well as potential therapeutic targets for the future.
导入和目的:重症哮喘患者约占所有哮喘患者的 3%至 10%。与非重度哮喘患者相比,他们的住院率和治疗费用都更高。以前,由于无法接受的副作用,这些患者的治疗选择有限。然而,生物疗法的出现为这些患者提供了前景广阔的靶向治疗。知识现状:生物疗法针对的是在哮喘发病机制中起关键作用的炎症调节因子,尤其是对高 T2 细胞患者。这些疗法在减轻哮喘症状、改善肺功能、减少口服皮质类固醇的使用以及提高患者生活质量方面取得了良好的效果。结论:本文回顾了波兰目前批准的生物药物的作用机制、疗效和适应症,以及未来潜在的治疗目标。
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引用次数: 0
Classification, Symptoms, Treatment and Preventive Strategies of Diabetes. A guide to the basic 糖尿病的分类、症状、治疗和预防策略。糖尿病基本知识指南
Pub Date : 2024-05-17 DOI: 10.12775/jehs.2024.70.50192
Magda Madoń, Patrycja Proszowska, Daria Sieniawska, Adrianna Orzeł, Aleksandra Pich-Czekierda, Zuzanna Kotowicz, Julia Sieniawska
Introduction Diabetes is a chronic metabolic disorder characterized by impaired insulin secretion and action. Risk factors for diabetes include age, obesity, low physical activity, hypertension, lipid disorders, and genetic predisposition. Symptoms of diabetes typically include frequent urination, weight loss, excessive thirst, weakness, fatigue, susceptibility to fungal infections and recurrent boils. Diabetes is a prevalent and significant societal concern, often causing anxiety, uncertainty and a sense of danger upon diagnosis. Aim of the study The aim of the study is to provide a comprehensive analysis of diabetes, including its classification, characteristic symptoms, the most frequently occurring diabetes-related complications, and preventive strategies. Through a detailed discussion of these issues, our goal is to increase public awareness of diabetes and provide readers with comprehensive knowledge about this disease. Material and method This article presents the current state of knowledge about diabetes. A literature review was conducted using the PubMed, Google Scholar and Web of Science databases, utilizing keywords such as "diabetes", "diabetes mellitus", "diabetes complications". Results The number of people with diabetes has continued to rise. Scientists predict that in a few decades, this number could reach more than half a billion globally. Many individuals may not realize that they are at risk for this civilization disease, often due to unhealthy lifestyle choices such as smoking, obesity, and lack of physical activity. Early initiation of treatment is crucial in preventing serious complications. Despite living with diabetes for years, some patients still report insufficient knowledge about their condition. Therefore, educating patients about the nature of the disease and its treatment is essential for improving their quality of life.
导言 糖尿病是一种慢性代谢性疾病,其特点是胰岛素分泌和作用受损。糖尿病的危险因素包括年龄、肥胖、体力活动少、高血压、血脂紊乱和遗传易感性。糖尿病的症状通常包括尿频、体重减轻、过度口渴、虚弱、疲劳、易受真菌感染和反复长疖子。糖尿病是一个普遍存在的重大社会问题,一旦确诊,往往会引起焦虑、不确定感和危险感。研究目的 本研究旨在全面分析糖尿病,包括其分类、特征性症状、最常发生的糖尿病相关并发症以及预防策略。通过对这些问题的详细讨论,我们的目标是提高公众对糖尿病的认识,为读者提供有关该疾病的全面知识。材料和方法 本文介绍了糖尿病的知识现状。我们利用 PubMed、Google Scholar 和 Web of Science 数据库,使用 "糖尿病"、"糖尿病"、"糖尿病并发症 "等关键词进行了文献综述。结果 糖尿病患者人数持续上升。科学家预测,几十年后,全球糖尿病患者人数将超过 5 亿。许多人可能没有意识到自己有患这种文明病的风险,这往往是由于选择了不健康的生活方式,如吸烟、肥胖和缺乏体育锻炼。及早开始治疗对于预防严重并发症至关重要。尽管已患糖尿病多年,但一些患者仍表示对自己的病情缺乏足够的了解。因此,让患者了解疾病的性质和治疗方法对于提高他们的生活质量至关重要。
{"title":"Classification, Symptoms, Treatment and Preventive Strategies of Diabetes. A guide to the basic","authors":"Magda Madoń, Patrycja Proszowska, Daria Sieniawska, Adrianna Orzeł, Aleksandra Pich-Czekierda, Zuzanna Kotowicz, Julia Sieniawska","doi":"10.12775/jehs.2024.70.50192","DOIUrl":"https://doi.org/10.12775/jehs.2024.70.50192","url":null,"abstract":"Introduction \u0000Diabetes is a chronic metabolic disorder characterized by impaired insulin secretion and action. Risk factors for diabetes include age, obesity, low physical activity, hypertension, lipid disorders, and genetic predisposition. Symptoms of diabetes typically include frequent urination, weight loss, excessive thirst, weakness, fatigue, susceptibility to fungal infections and recurrent boils. Diabetes is a prevalent and significant societal concern, often causing anxiety, uncertainty and a sense of danger upon diagnosis. \u0000Aim of the study \u0000The aim of the study is to provide a comprehensive analysis of diabetes, including its classification, characteristic symptoms, the most frequently occurring diabetes-related complications, and preventive strategies. Through a detailed discussion of these issues, our goal is to increase public awareness of diabetes and provide readers with comprehensive knowledge about this disease. \u0000Material and method \u0000This article presents the current state of knowledge about diabetes. A literature review was conducted using the PubMed, Google Scholar and Web of Science databases, utilizing keywords such as \"diabetes\", \"diabetes mellitus\", \"diabetes complications\". \u0000Results \u0000The number of people with diabetes has continued to rise. Scientists predict that in a few decades, this number could reach more than half a billion globally. Many individuals may not realize that they are at risk for this civilization disease, often due to unhealthy lifestyle choices such as smoking, obesity, and lack of physical activity. Early initiation of treatment is crucial in preventing serious complications. Despite living with diabetes for years, some patients still report insufficient knowledge about their condition. Therefore, educating patients about the nature of the disease and its treatment is essential for improving their quality of life.","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"116 49","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141126722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
I'm sick? I don't train!" – Relation between training during upper respiratory infection and myocarditis 我生病了?我不训练!"- 上呼吸道感染期间的训练与心肌炎的关系
Pub Date : 2024-05-17 DOI: 10.12775/jehs.2024.70.49033
Michał Żuchowski, Dominika Mańdziuk, Patrycja Niewinna, Przemysław Zaroda, Paweł Dąda, Paweł Pawlik, Wojciech Kołodziej, Klaudia Kołodziej, Jakub Wawrzkowicz, Monika Korga
IntrocudtionMyocarditis is one of the leading causes of sudden cardiac deaths among athletes. One of the factors increasing the risk of this disease is engaging in sports training during an infection. Many athletes, regardless of their level of advancement, are not aware of the risks associated with training during an infection, and those who are aware often ignore them and continue training. Purpose Assessment of behaviors and awareness among runners in Poland regarding the risk of developing myocarditis as a result of training during respiratory tract infections. Material and method In December 2023, a voluntary and anonymous online survey was conducted among a group of 399 adult runners from Poland. The survey included 13 questions, consisting of 11 single-choice questions and 2 multiple-choice questions. Results The percentage of individuals who do not associate training during an infection with an increased risk of myocarditis amounts to as much as 44.4% (n=177), while a staggering 86.7% (n=346) of respondents declare that they undertake training during respiratory infections. Conslusion After analyzing the survey, it's evident that while the Polish running community recognizes the risks of training during infections, many still exercise despite symptoms. Although most understand that intense training and early return to sports can harm health, awareness of myocarditis risks from exertion during infection is lacking. Despite protocols for post-illness return to sports, there's a need for campaigns to educate the running community on infection-related training risks.  
导言心肌炎是导致运动员心脏性猝死的主要原因之一。增加这种疾病风险的因素之一是在感染期间进行体育训练。许多运动员,无论水平高低,都没有意识到在感染期间进行训练所带来的风险,而那些意识到风险的运动员往往会忽视这些风险并继续训练。目的 评估波兰长跑运动员对在呼吸道感染期间训练导致心肌炎风险的行为和认识。材料和方法 2023 年 12 月,我们对来自波兰的 399 名成年跑步者进行了自愿和匿名的在线调查。调查包括 13 个问题,包括 11 个单选题和 2 个多选题。结果 不认为在感染期间进行训练会增加患心肌炎风险的受访者比例高达 44.4%(n=177),而有 86.7%(n=346)的受访者声称他们在呼吸道感染期间进行训练。结论 对调查进行分析后发现,尽管波兰跑步爱好者认识到在感染期间进行训练的风险,但许多人仍然不顾症状进行锻炼。虽然大多数人都了解高强度训练和过早恢复运动会损害健康,但对感染期间因劳累引发心肌炎的风险却缺乏认识。尽管制定了病后恢复运动的规程,但仍有必要开展宣传活动,让跑步爱好者了解与感染相关的训练风险。
{"title":"I'm sick? I don't train!\" – Relation between training during upper respiratory infection and myocarditis","authors":"Michał Żuchowski, Dominika Mańdziuk, Patrycja Niewinna, Przemysław Zaroda, Paweł Dąda, Paweł Pawlik, Wojciech Kołodziej, Klaudia Kołodziej, Jakub Wawrzkowicz, Monika Korga","doi":"10.12775/jehs.2024.70.49033","DOIUrl":"https://doi.org/10.12775/jehs.2024.70.49033","url":null,"abstract":"IntrocudtionMyocarditis is one of the leading causes of sudden cardiac deaths among athletes. One of the factors increasing the risk of this disease is engaging in sports training during an infection. Many athletes, regardless of their level of advancement, are not aware of the risks associated with training during an infection, and those who are aware often ignore them and continue training. \u0000Purpose \u0000Assessment of behaviors and awareness among runners in Poland regarding the risk of developing myocarditis as a result of training during respiratory tract infections. \u0000Material and method \u0000In December 2023, a voluntary and anonymous online survey was conducted among a group of 399 adult runners from Poland. The survey included 13 questions, consisting of 11 single-choice questions and 2 multiple-choice questions. \u0000Results \u0000The percentage of individuals who do not associate training during an infection with an increased risk of myocarditis amounts to as much as 44.4% (n=177), while a staggering 86.7% (n=346) of respondents declare that they undertake training during respiratory infections. \u0000Conslusion \u0000After analyzing the survey, it's evident that while the Polish running community recognizes the risks of training during infections, many still exercise despite symptoms. Although most understand that intense training and early return to sports can harm health, awareness of myocarditis risks from exertion during infection is lacking. Despite protocols for post-illness return to sports, there's a need for campaigns to educate the running community on infection-related training risks. \u0000 ","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140962767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cervical cancer - is there anything to worry about? Research on knowledge and awareness of cervical cancer among Poles 宫颈癌--有什么值得担心的吗?关于波兰人对宫颈癌的了解和认识的研究
Pub Date : 2024-05-16 DOI: 10.12775/jehs.2024.69.48460
Dominika Mańdziuk, Klaudia Kołodziej, Michał Żuchowski, Patrycja Niewinna, Przemysław Zaroda, Paweł Dąda, Paweł Pawlik, Wojciech Kołodziej, Jakub Wawrzkowicz, Monika Korga
Cervical cancer poses a global health challenge, being one of the most common cancers of the reproductive organs and a leading cause of morbidity and mortality worldwide. The disease, resulting from infection with the human papillomavirus (HPV), tends to develop in advanced stages, significantly complicating effective treatment. Despite advancements in medicine, diagnostics, and therapy, cervical cancer remains a serious public health threat. Periodic surveillance through screening has significantly reduced the incidence of cervical cancer; however, in Poland, there is a notable gap between potentially available preventive measures and their actual utilization by the population. It has been observed that only around 20% of Polish women participate in screening programs, contributing to Poland having one of the highest rates of incidence and mortality from this type of cancer in Europe. This leads to the conclusion that cervical cancer constitutes an unresolved oncological and epidemiological problem in Poland. In the context of these challenges, a crucial aspect is understanding the level of public knowledge about cervical cancer, its risk factors, and available preventive measures. This study focuses on evaluating the societal knowledge regarding the risk factors of cervical cancer, identifying existing gaps, and suggesting potential areas for educational interventions.
宫颈癌是生殖器官最常见的癌症之一,也是全球发病率和死亡率的主要原因,对全球健康构成挑战。这种由人类乳头瘤病毒(HPV)感染引起的疾病往往发展到晚期,大大增加了有效治疗的难度。尽管在医学、诊断和治疗方面取得了进步,但宫颈癌仍然是一个严重的公共卫生威胁。通过筛查进行定期监测已大大降低了宫颈癌的发病率;然而,在波兰,潜在的预防措施与人们的实际利用率之间存在着明显的差距。据观察,只有约 20% 的波兰妇女参加了筛查计划,这导致波兰成为欧洲此类癌症发病率和死亡率最高的国家之一。由此得出的结论是,宫颈癌在波兰是一个尚未解决的肿瘤学和流行病学问题。面对这些挑战,一个至关重要的方面是了解公众对宫颈癌、其风险因素和现有预防措施的了解程度。本研究的重点是评估社会对宫颈癌风险因素的了解程度,找出现有差距,并提出教育干预的潜在领域。
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引用次数: 0
Modern Approaches and Future Perspectives on Breast and Ovarian Cancer Prevention Strategies in BRCA1 and BRCA2 Mutation Carriers: A Literature Overview BRCA1 和 BRCA2 基因突变携带者乳腺癌和卵巢癌预防策略的现代方法和未来展望:文献综述
Pub Date : 2024-05-16 DOI: 10.12775/jehs.2024.69.49454
Sandra Sarnacka, Jakub Kordialik, Julia Koćwin, Paula Bieganek, Bartosz Sadłowski, Stanisław Łukaszewicz, Piotr Pawłowski, Julia Rybak, Michał Tokarski, Angelika Banasiak
Individuals with BRCA1 and BRCA2 mutations face significantly heightened likelihood of developing breast and ovarian cancers.  Besides some lifestyle recommendations, like maintaining physical activity, healthy BMI, possibly early parenthood and breastfeeding, the management of BRCA1/2 mutation carriers includes gene mutation early-detection, screening, risk-reducing surgeries, and chemoprevention. Various prevention strategies exist, all aimed at monitoring patients and mitigating the cancer risks. However, even with the existence of national and international guidelines to direct prevention efforts, there is no ideal protocol that would be universally applicable for all individuals with mutated BRCA gene. This article aims to delve into the currently available surveillance and preventive strategies and explore the potential future avenues for early detection and risk reduction in BRCA mutation carriers.
BRCA1 和 BRCA2 基因突变携带者罹患乳腺癌和卵巢癌的几率大大增加。 除了一些生活方式建议(如保持体育锻炼、健康的体重指数、可能的早育和母乳喂养)外,对 BRCA1/2 基因突变携带者的管理还包括基因突变的早期检测、筛查、降低风险的手术和化学预防。目前已有各种预防策略,其目的都是监测患者并降低癌症风险。然而,即使存在指导预防工作的国家和国际指南,也没有一个理想的方案能普遍适用于所有 BRCA 基因突变的个体。本文旨在深入探讨目前可用的监测和预防策略,并探索未来早期检测和降低 BRCA 基因突变携带者风险的潜在途径。
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引用次数: 0
Diagnostic and therapeutic process of respiratory disorders during sleep 睡眠呼吸障碍的诊断和治疗过程
Pub Date : 2024-05-16 DOI: 10.12775/jehs.2024.68.50188
Karolina Maliszewska, Izabela Oleksak, Iwona Welian-Polus, Karolina Gendek, Wiktoria Wilanowska, Kamila Babkiewicz-Jahn, Justyna Matuszewska
Introduction and purpose Sleep apnea is a disturbance of sleep that affects about 10% of adult population and is not easily detected due to unspecific symptoms. The aim of this literature review is to present, respectively, obstructive sleep apnea and central sleep apnea symptoms and integrate the available data in the literature regarding the pathogenesis and treatment methods. Materials and methods A review of literature was performed using PubMed and Google Scholar database. The search criteria included keywords such as sleep apnea, obstructive sleep apnea treatment, central sleep apnea treatment. State of knowledge Sleep disturbances that involve breathing can be categorized as obstructive sleep apnea (OSA) and central sleep apnea. First one is associated with the obstruction of the upper airways and the second one – with malfunctioning breathing generator in the pontomedullary breathing pacemaker. Symptoms are unspecific which makes diagnostic process difficult. However, the right diagnosis and treatment may prevent patients from developing many cardiovascular diseases. Treatment options for OSA include: CPAP, reducing body weight, changing sleep position, braces and surgeries; for CSA: CPAP and acetazolamide. Conclusions OSA and CSA need to be further investigated in order to find more precise ways of diagnosis and treatment, as these diseases remain underreported. It is worth noting, that these conditions predispose to serious diseases, e.g. stroke. Therefore, developing new treatment techniques would beneficial for the health of population.
导言和目的 睡眠呼吸暂停是一种睡眠障碍,约影响 10%的成年人,由于症状不明确,不易被发现。本文献综述旨在分别介绍阻塞性睡眠呼吸暂停和中枢性睡眠呼吸暂停的症状,并整合有关发病机制和治疗方法的现有文献数据。材料和方法 使用 PubMed 和谷歌学术数据库进行文献综述。搜索标准包括睡眠呼吸暂停、阻塞性睡眠呼吸暂停治疗、中枢性睡眠呼吸暂停治疗等关键词。知识现状 涉及呼吸的睡眠障碍可分为阻塞性睡眠呼吸暂停(OSA)和中枢性睡眠呼吸暂停。前者与上呼吸道阻塞有关,后者则与髓质呼吸起搏器的呼吸发生器功能失常有关。症状没有特异性,因此诊断过程比较困难。然而,正确的诊断和治疗可以防止患者患上多种心血管疾病。治疗 OSA 的方法包括CPAP、减轻体重、改变睡眠姿势、支具和手术;对于 CSA:CPAP 和乙酰唑胺。结论 OSA 和 CSA 需要进一步研究,以便找到更精确的诊断和治疗方法,因为这些疾病的报告率仍然很低。值得注意的是,这些疾病容易引发中风等严重疾病。因此,开发新的治疗技术将有益于人们的健康。
{"title":"Diagnostic and therapeutic process of respiratory disorders during sleep","authors":"Karolina Maliszewska, Izabela Oleksak, Iwona Welian-Polus, Karolina Gendek, Wiktoria Wilanowska, Kamila Babkiewicz-Jahn, Justyna Matuszewska","doi":"10.12775/jehs.2024.68.50188","DOIUrl":"https://doi.org/10.12775/jehs.2024.68.50188","url":null,"abstract":"Introduction and purpose \u0000Sleep apnea is a disturbance of sleep that affects about 10% of adult population and is not easily detected due to unspecific symptoms. The aim of this literature review is to present, respectively, obstructive sleep apnea and central sleep apnea symptoms and integrate the available data in the literature regarding the pathogenesis and treatment methods. \u0000Materials and methods \u0000A review of literature was performed using PubMed and Google Scholar database. The search criteria included keywords such as sleep apnea, obstructive sleep apnea treatment, central sleep apnea treatment. \u0000State of knowledge \u0000Sleep disturbances that involve breathing can be categorized as obstructive sleep apnea (OSA) and central sleep apnea. First one is associated with the obstruction of the upper airways and the second one – with malfunctioning breathing generator in the pontomedullary breathing pacemaker. Symptoms are unspecific which makes diagnostic process difficult. However, the right diagnosis and treatment may prevent patients from developing many cardiovascular diseases. Treatment options for OSA include: CPAP, reducing body weight, changing sleep position, braces and surgeries; for CSA: CPAP and acetazolamide. \u0000Conclusions \u0000OSA and CSA need to be further investigated in order to find more precise ways of diagnosis and treatment, as these diseases remain underreported. It is worth noting, that these conditions predispose to serious diseases, e.g. stroke. Therefore, developing new treatment techniques would beneficial for the health of population.","PeriodicalId":15567,"journal":{"name":"Journal of Education, Health and Sport","volume":"31 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140966490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Education, Health and Sport
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