The health problem of pregnant women is a public health problem that needs to get major attention because it has an impact on the quality of life and future generations. Then examine the data/information empirically and theoretically. The sample units in this study were the skills of cadres in increasing the Immunity of Pregnant Women with the independent variables namely knowledge and attitudes. The sampling technique in this study was total sampling, then a sample of 85 cadres was obtained in the two puskesmas. The data collected is primary data, obtained from questionnaires filled out by health cadres, based on the data that has been obtained, then processing and analyzing the data is carried out according to the research objectives, and presented in tabular form accompanied by narrative as an explanation of the table. The research results obtained were that there was a significant relationship between the knowledge of cadres and the skills of cadres in carrying out health promotion to increase the immunity of pregnant women (P value 0.032 < 0.05). There is a significant relationship between the knowledge of pregnant women's immunity and the skills of cadres (P value = 0.025 < 0.05), there is a significant relationship between the attitudes of cadres and the skills of cadres in health promotion to increase the immunity of pregnant women (P value = 0.004 < 0.05). The most significant factors for the skills of cadres in carrying out health promotion to increase the immunity of pregnant women.