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Acute effect of dark chocolate intake before high-intensity resistance exercise on arterial stiffness in healthy young men 高强度抗阻运动前摄入黑巧克力对健康年轻男性动脉硬化的急性影响
IF 2.4 2区 医学 Q2 SPORT SCIENCES Pub Date : 2025-10-01 Epub Date: 2025-08-25 DOI: 10.1016/j.jesf.2025.08.005
Urara Hata , Yuto Hashimoto , Midori Natsume , Takanobu Okamoto

Aims

This study investigated the effect of dark chocolate (DC) intake before resistance exercise (RE) on arterial stiffness.

Methods

Twelve healthy adult males (age, 23.0 ± 1.0 years) performed DC or white chocolate (WC) intake trial on separate days in a randomized crossover trials. Participants consumed 50g of DC containing 1285 mg cocoa polyphenols or an isocaloric amount of WC 50g without polyphenols. All participants performed 5 sets of 5 repetitions using 80 % of the 1 repetition maximum (1RM) bench press and 5 sets of 10 repetitions using 70 % of the 1RM biceps curl. Brachial–ankle pulse wave velocity (baPWV), blood pressure, and heart rate were measured before chocolate intake (baseline); and before (at 60 min after chocolate intake), immediately after, and at 30 and 60 min after completing the RE.

Results

In both trials, there was a significant increase in baPWV immediately after the RE compared with baseline (baseline: DC 1103 ± 94 cm/s, WC 1108 ± 167 cm/s; immediately after RE: DC 1300 ± 187 cm/s, WC 1325 ± 178 cm/s; P < 0.05). In the DC intake trial, baPWV decreased to 1210 ± 180 cm/s at 30 min and 1155 ± 134 cm/s at 60 min after RE, compared to immediately after RE (P < 0.05). In contrast, in the WC intake trial baPWV was decreased to 1222 ± 176 cm/s at 60 min after RE compared to immediately after RE (P < 0.05).

Conclusion

These results suggest that in comparison with WC intake, DC intake before RE might quickly reduce post-exercise increased arterial stiffness. Clinical Trials Registry Number: UMIN000052616.
目的探讨抗阻运动(RE)前摄入黑巧克力(DC)对动脉硬化的影响。方法12名健康成年男性(年龄23.0±1.0岁)采用随机交叉试验,在不同的日子分别进行DC或白巧克力(WC)摄入试验。参与者摄入50g含有1285毫克可可多酚的DC或50g不含多酚的等量WC。所有参与者都进行了5组5次重复,使用80%的1次最大重复(1RM)卧推和5组10次重复,使用70%的1RM二头肌弯曲。在巧克力摄入前(基线)测量肱-踝脉搏波速度(baPWV)、血压和心率;结果在两项试验中,与基线(基线:DC为1103±94 cm/s, WC为1108±167 cm/s; RE后立即:DC为1300±187 cm/s, WC为1325±178 cm/s; P < 0.05)相比,RE后立即的baPWV显著增加。在直流吸入试验中,与直接吸入相比,吸入后30分钟和60分钟的baPWV分别降至1210±180 cm/s和1155±134 cm/s (P < 0.05)。相比之下,在进食WC试验中,与立即进食相比,进食后60分钟的baPWV降至1222±176 cm/s (P < 0.05)。结论与摄入WC相比,运动前摄入DC可迅速降低运动后增加的动脉僵硬度。临床试验注册号:UMIN000052616。
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引用次数: 0
Impact of aerobic exercise on immune components across healthy and diseased populations: A systematic review and meta-analysis of randomized controlled trials 有氧运动对健康和患病人群免疫成分的影响:随机对照试验的系统回顾和荟萃分析
IF 2.4 2区 医学 Q2 SPORT SCIENCES Pub Date : 2025-10-01 Epub Date: 2025-09-09 DOI: 10.1016/j.jesf.2025.09.002
Gengxin Dong , Xueying He , Jiya He , Dapeng Bao , Qi Gao , Junhong Zhou

Background

Aerobic exercise may improve immune component quantities in healthy and diseased populations, but its effects across different health conditions and immune systems remain unclear. This review examined its impact on immune components in both populations.

Methods

A search in June 2025 across four databases included randomized controlled studies on aerobic exercise's effects on immune components in adults. Data (M ± SD) were extracted and converted to standardized mean difference (SMD) using random-effect meta-analysis.

Results

Seventeen studies (502 participants) were included. The meta-analysis results showed long-term aerobic exercise increased T-cell counts in diseased individuals (p < 0.05) but not in healthy ones (p > 0.05). It significantly reduced IgA levels in healthy participants compared to non-exercising controls (p < 0.05), potentially counteracting natural temporal increases observed in sedentary populations, without affecting IgG, IgM, leukocytes, neutrophils, or monocytes in either group (p > 0.05). Single-pass exercise did not alter leukocytes, lymphocytes, CD3+, or NK cells in healthy participants (p > 0.05).

Conclusions

Long-term aerobic exercise primarily affects adaptive immune components, benefiting individuals with unstable immune conditions. Single-pass exercise has no effect on healthy populations, making long-term interventions more suitable for improving adaptive immunity in unstable immune states.

Systematic review registration

www.crd.york.ac.uk/PROSPERO/, identifier: CRD42024546696.
有氧运动可以提高健康和患病人群的免疫成分数量,但其对不同健康状况和免疫系统的影响尚不清楚。本综述研究了其对两种人群免疫成分的影响。方法于2025年6月在四个数据库中检索了有氧运动对成人免疫成分影响的随机对照研究。提取数据(M±SD),采用随机效应meta分析转换为标准化平均差(SMD)。结果纳入17项研究(502名受试者)。荟萃分析结果显示,长期有氧运动增加了患病个体的t细胞计数(p < 0.05),而没有增加健康个体的t细胞计数(p < 0.05)。与不运动的对照组相比,它显著降低了健康参与者的IgA水平(p < 0.05),潜在地抵消了久坐人群中观察到的自然时间增加,而不影响两组的IgG、IgM、白细胞、中性粒细胞或单核细胞(p < 0.05)。单次运动没有改变健康参与者的白细胞、淋巴细胞、CD3+或NK细胞(p > 0.05)。结论长期有氧运动主要影响适应性免疫成分,有利于免疫状态不稳定的个体。单次运动对健康人群没有影响,使得长期干预更适合于在不稳定的免疫状态下提高适应性免疫。系统综述注册www.crd.york.ac.uk/PROSPERO/,标识符:CRD42024546696。
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引用次数: 0
Compared to moderate-intensity continuous training, short-term high-intensity interval training demonstrates enhanced effects on metabolic flexibility in adult males with obesity 与中等强度的连续训练相比,短期高强度间歇训练对成年肥胖男性代谢灵活性的影响更大
IF 2.4 2区 医学 Q2 SPORT SCIENCES Pub Date : 2025-10-01 Epub Date: 2025-07-26 DOI: 10.1016/j.jesf.2025.07.005
Jia-Zheng Zhang , Xiao-Mei Liu , Shi-Qi Lu , Zhen-Bo Cao , Zheng Zhu

Background

The aim of this study was to assess the effects of short-term high-intensity interval training (HIIT) and moderate-intensity continuous aerobic training (MICT) with matched energy expenditure on metabolic flexibility and other metabolic parameters in adult male individuals with obesity.

Methods

Twenty male individuals with obesity (age: 21.4 ± 1.5 years; body mass index: 31.0 ± 3.6 kg/m2) were enrolled in this crossover design study. Participants were randomly allocated to an intervention sequence of 1) 3 consecutive days of HIIT (30 min, 6 × 2.5 min bouts at 90 % Peak Oxygen Uptake (VO2peak), alternated with 2.5 min active recovery periods [25 % VO2peak]), or 2) three consecutive days of MICT (60 min at 50 % VO2peak), with a washout period of 1 week. Respiratory quotient (RQ), glucose, C-peptide, insulin, and non-esterified fatty acid (NEFA) levels were measured both during fasting and throughout a 180 min oral glucose tolerance test (OGTT), conducted before and after the intervention. The incremental area under the curve (iAUC) and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) were derived. ΔRQ was defined as the average RQ during the OGTT minus fasting RQ.

Results

Short-term exercise intervention significantly reduced HOMA-IR in male individuals with obesity (P < 0.001) and concurrently increased the Matsuda index (P = 0.001). Both exercise interventions led to a similar decrease in fasting RQ (P = 0.001), C-peptide, insulin, and HOMA-IR (P < 0.001). Additionally, they reduced the iAUC for glucose and insulin during the OGTT (P < 0.001). The ΔRQ and the RQ iAUC in the HIIT group were significantly higher than those in the MICT group, and different exercise intensities exhibited interactive effects within groups for RQ iAUC and ΔRQ (P = 0.013 and P = 0.012).

Conclusions

Two short-term exercise interventions similarly improved glucose tolerance, with HIIT demonstrating a more advantageous effect on metabolic flexibility than MICT in male individuals with obesity.

Trial registration

The trial was officially registered at www.chictr.org.cn (ChiCTR2300072884).
本研究的目的是评估短期高强度间歇训练(HIIT)和中等强度连续有氧训练(MICT)匹配能量消耗对成年男性肥胖个体代谢柔韧性和其他代谢参数的影响。方法男性肥胖患者20例(年龄:21.4±1.5岁;体重指数:31.0±3.6 kg/m2)的患者被纳入这项交叉设计研究。参与者被随机分配到1)连续3天的HIIT(30分钟,6 × 2.5分钟,90%峰值摄氧量),交替进行2.5分钟的活跃恢复期[25%峰值摄氧量]),或2)连续3天的MICT(60分钟,50%峰值摄氧量),洗脱期为1周。呼吸商(RQ)、葡萄糖、c肽、胰岛素和非酯化脂肪酸(NEFA)水平均在禁食期间和干预前后进行的180分钟口服葡萄糖耐量试验(OGTT)中测量。导出了胰岛素抵抗的增量曲线下面积(iAUC)和稳态模型评估(HOMA-IR)。ΔRQ定义为OGTT期间的平均RQ减去禁食RQ。结果短期运动干预可显著降低男性肥胖患者的HOMA-IR (P <;0.001),同时增加了Matsuda指数(P = 0.001)。两种运动干预均导致空腹RQ (P = 0.001)、c肽、胰岛素和HOMA-IR (P <;0.001)。此外,他们还降低了OGTT期间葡萄糖和胰岛素的iAUC (P <;0.001)。HIIT组的ΔRQ和RQ iAUC均显著高于MICT组,组内不同运动强度对RQ iAUC和ΔRQ有交互作用(P = 0.013和P = 0.012)。结论:两种短期运动干预同样改善了葡萄糖耐量,在男性肥胖患者中,HIIT比MICT对代谢灵活性的影响更有利。试验注册该试验已在www.chictr.org.cn (ChiCTR2300072884)上正式注册。
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引用次数: 0
Impact of acute and chronic cycling exercise on microvascular reactivity of the upper and lower extremity muscles in young healthy females 急性和慢性自行车运动对年轻健康女性上肢和下肢肌肉微血管反应性的影响
IF 2.4 2区 医学 Q2 SPORT SCIENCES Pub Date : 2025-10-01 Epub Date: 2025-06-18 DOI: 10.1016/j.jesf.2025.06.004
Xuanyao Liu, Bin Leng, Haizhen Huang, Yadan He, Chuan Zhang

Background

Few studies have evaluated the impact of exercise on specific skeletal muscle microvascular function, despite its importance. This study aimed to assess the acute and chronic effects of cycling exercise on microvascular reactivity in the upper and lower extremities of young healthy females.

Methods

Eighteen young healthy females performed an acute bout of cycling exercise on a cycle ergometer at 75 % of their maximal heart rate for 30 min, both before and after cycling training three times a week for eight weeks. For each bout of acute exercise, microvascular function in the biceps brachii (BB) and vastus lateralis (VL) muscles was assessed using near-infrared spectroscopy coupled with the post-occlusive reactive hyperemia technique, measured pre-exercise and at 20-, 40-, and 60-min post-exercise. Body composition was assessed using dual-energy X-ray absorptiometry before and after training.

Results

Total body fat mass, abdominal fat mass and leg fat mass were significantly reduced by training. Before training, cycling exercise acutely improved microvascular reactivity in BB but not in VL. Eight weeks of cycling training significantly improved resting microvascular reactivity in BB but not in VL. Training had no impact on post-exercise microvascular reactivity at VL, but elicited improvement in BB.

Conclusions

Acute and chronic cycling exercise enhanced skeletal muscle microvascular responses in the upper extremity of young healthy females, but this effect was not observed in the lower extremity. Training enhanced post-exercise microvascular responses at upper extremity but not lower extremity.
尽管运动很重要,但很少有研究评估运动对特定骨骼肌微血管功能的影响。本研究旨在评估骑车运动对年轻健康女性上肢和下肢微血管反应性的急性和慢性影响。方法18名年轻健康女性在自行车计力器上以75%的最大心率进行30分钟的急性自行车运动,每周三次,持续8周。对于每一轮急性运动,使用近红外光谱结合闭塞后反应性充血技术评估肱二头肌(BB)和股外侧肌(VL)的微血管功能,并在运动前和运动后20、40和60分钟测量。在训练前后用双能x线吸收仪评估身体成分。结果训练后总体脂量、腹部脂肪量和腿部脂肪量均显著降低。在训练前,骑车运动能明显改善BB的微血管反应性,但对VL没有改善。8周的自行车训练显著改善了BB的静息微血管反应性,但没有改善VL。训练对运动后VL的微血管反应性没有影响,但引起BB的改善。结论急性和慢性自行车运动增强了年轻健康女性上肢骨骼肌微血管反应,但在下肢没有观察到这种作用。训练增强了运动后上肢的微血管反应,但对下肢没有作用。
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引用次数: 0
Effects of two different doses of HIFT on physical function, cognitive performance, and quality of life in older adults with mild cognitive impairment: A randomized controlled trial 两种不同剂量的HIFT对轻度认知障碍老年人身体功能、认知表现和生活质量的影响:一项随机对照试验
IF 2.4 2区 医学 Q2 SPORT SCIENCES Pub Date : 2025-10-01 Epub Date: 2025-10-04 DOI: 10.1016/j.jesf.2025.10.004
Diego Fernando Afanador-Restrepo , Yulieth Rivas-Campo , Carlos Mario Basto-Cardona , David Alejandro Gonzalez-Bustamante , Agustin Aibar-Almazan , Yolanda Castellote-Caballero , Fidel Hita-Contreras , Eduardo Guzmán-Muñoz , Yeny Concha-Cisternas
Background/Objective: Mild cognitive impairment (MCI) compromises physical and mental function in older adults and increases the risk of dementia. High-Intensity Functional Training (HIFT) is a promising intervention, but the optimal dose-response for improving cognitive and physical outcomes in this population remains unclear.

Methods

A randomized controlled trial was conducted with 224 older adults (≥65 years) allocated to three groups: high-dose HIFT (4 sessions of 60 min/week), low-dose HIFT (2 sessions of 45 min/week), and control (non-exercise activities). The intervention lasted 12 weeks. Primary outcomes included cognitive function (MAAS, MoCA, TMT A/B, VFAT, DSST), physical fitness (Senior Fitness Test, Tinetti), and quality of life (SF-36, PSQI). A repeated-measures ANOVA was used to examine the time × group interaction.

Results

Significant time × group interactions were observed for MAAS (F = 20.50; p < 0.001; η2G = 0.005), MoCA (F = 17.40; p < 0.001; η2G = 0.034), TMT A (F = 38.60; p < 0.001; η2G = 0.098), and VFAT (F = 109.00; p < 0.001; η2G = 0.101), with greater improvements in both HIFT groups compared to control. For quality of life, significant interactions were found across all SF-36 dimensions, notably in Vitality (F = 76.20; p < 0.001; η2G = 0.095) and Emotional Role (F = 23.00; p < 0.001; η2G = 0.032). Physical fitness also improved, with significant effects in the 6-Minute Walk Test (F = 29.80; p < 0.001; η2G = 0.108) and 8-Foot Up-and-Go (F = 81.00; p < 0.001; η2G = 0.191).

Conclusion

Both high- and low-dose HIFT programs improved cognitive, physical, and quality-of-life outcomes in older adults with MCI. The low-dose intervention achieved similar effects to the high-dose protocol, offering a time-efficient and scalable approach for implementation in clinical and community settings.
背景/目的:轻度认知障碍(MCI)损害老年人的身心功能,并增加痴呆的风险。高强度功能训练(High-Intensity Functional Training, HIFT)是一种很有前景的干预手段,但在这一人群中,改善认知和身体状况的最佳剂量反应尚不清楚。方法对224名年龄≥65岁的老年人进行随机对照试验,将其分为3组:高剂量HIFT组(4次60分钟/周)、低剂量HIFT组(2次45分钟/周)和对照组(无运动活动)。干预持续12周。主要指标包括认知功能(MAAS、MoCA、TMT A/B、VFAT、DSST)、体能(Senior fitness Test、Tinetti)和生活质量(SF-36、PSQI)。采用重复测量方差分析来检验时间×组相互作用。结果MAAS (F = 20.50; p < 0.001; η2G = 0.005)、MoCA (F = 17.40; p < 0.001; η2G = 0.034)、TMT A (F = 38.60; p < 0.001; η2G = 0.098)和VFAT (F = 109.00; p < 0.001; η2G = 0.101)的时间组间相互作用显著,HIFT组与对照组相比均有较大改善。对于生活质量,在SF-36的所有维度中都发现了显著的相互作用,特别是在活力(F = 76.20; p < 0.001; η2G = 0.095)和情感角色(F = 23.00; p < 0.001; η2G = 0.032)。身体素质也得到了改善,在6分钟步行测试(F = 29.80; p < 0.001; η2G = 0.108)和8英尺上下行走测试(F = 81.00; p < 0.001; η2G = 0.191)中效果显著。结论:高剂量和低剂量HIFT方案均可改善老年MCI患者的认知、身体和生活质量。低剂量干预取得了与高剂量方案相似的效果,为在临床和社区环境中实施提供了一种具有时间效率和可扩展的方法。
{"title":"Effects of two different doses of HIFT on physical function, cognitive performance, and quality of life in older adults with mild cognitive impairment: A randomized controlled trial","authors":"Diego Fernando Afanador-Restrepo ,&nbsp;Yulieth Rivas-Campo ,&nbsp;Carlos Mario Basto-Cardona ,&nbsp;David Alejandro Gonzalez-Bustamante ,&nbsp;Agustin Aibar-Almazan ,&nbsp;Yolanda Castellote-Caballero ,&nbsp;Fidel Hita-Contreras ,&nbsp;Eduardo Guzmán-Muñoz ,&nbsp;Yeny Concha-Cisternas","doi":"10.1016/j.jesf.2025.10.004","DOIUrl":"10.1016/j.jesf.2025.10.004","url":null,"abstract":"<div><div>Background/Objective: Mild cognitive impairment (MCI) compromises physical and mental function in older adults and increases the risk of dementia. High-Intensity Functional Training (HIFT) is a promising intervention, but the optimal dose-response for improving cognitive and physical outcomes in this population remains unclear.</div></div><div><h3>Methods</h3><div>A randomized controlled trial was conducted with 224 older adults (≥65 years) allocated to three groups: high-dose HIFT (4 sessions of 60 min/week), low-dose HIFT (2 sessions of 45 min/week), and control (non-exercise activities). The intervention lasted 12 weeks. Primary outcomes included cognitive function (MAAS, MoCA, TMT A/B, VFAT, DSST), physical fitness (Senior Fitness Test, Tinetti), and quality of life (SF-36, PSQI). A repeated-measures ANOVA was used to examine the time × group interaction.</div></div><div><h3>Results</h3><div>Significant time × group interactions were observed for MAAS (F = 20.50; p &lt; 0.001; η<sup>2</sup>G = 0.005), MoCA (F = 17.40; p &lt; 0.001; η<sup>2</sup>G = 0.034), TMT A (F = 38.60; p &lt; 0.001; η<sup>2</sup>G = 0.098), and VFAT (F = 109.00; p &lt; 0.001; η<sup>2</sup>G = 0.101), with greater improvements in both HIFT groups compared to control. For quality of life, significant interactions were found across all SF-36 dimensions, notably in Vitality (F = 76.20; p &lt; 0.001; η<sup>2</sup>G = 0.095) and Emotional Role (F = 23.00; p &lt; 0.001; η<sup>2</sup>G = 0.032). Physical fitness also improved, with significant effects in the 6-Minute Walk Test (F = 29.80; p &lt; 0.001; η<sup>2</sup>G = 0.108) and 8-Foot Up-and-Go (F = 81.00; p &lt; 0.001; η<sup>2</sup>G = 0.191).</div></div><div><h3>Conclusion</h3><div>Both high- and low-dose HIFT programs improved cognitive, physical, and quality-of-life outcomes in older adults with MCI. The low-dose intervention achieved similar effects to the high-dose protocol, offering a time-efficient and scalable approach for implementation in clinical and community settings.</div></div>","PeriodicalId":15793,"journal":{"name":"Journal of Exercise Science & Fitness","volume":"23 4","pages":"Pages 462-472"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145319908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing the effects of 25-minute electrical muscle stimulation vs. 90-minute full-body resistance training on body composition and strength: A 20-week intervention 比较25分钟肌肉电刺激与90分钟全身阻力训练对身体成分和力量的影响:为期20周的干预
IF 2.4 2区 医学 Q2 SPORT SCIENCES Pub Date : 2025-10-01 Epub Date: 2025-07-16 DOI: 10.1016/j.jesf.2025.07.002
Süleyman Ulupınar , Uğur Arı , Necip Fazıl Kishalı , İzzet İnce , Salih Çabuk , Cebrail Gençoğlu , Serhat Özbay

Objectives

Electromyostimulation (EMS) and traditional resistance training (TradRT) are widely used methods for improving muscle strength and body composition. However, comparative studies employing a multi-week longitudinal design remain limited. This study aimed to investigate the effects of 20 weeks of EMS vs. TradRT on body composition and strength performance in physically active adults.

Methods

Forty-six participants were randomly assigned to either the EMS group (n = 22) or the TradRT group (n = 24). The EMS group performed twice-weekly, 25-min whole-body EMS sessions, while the TradRT group completed twice-weekly, 90-min full-body resistance training sessions.

Results

Assessments of body weight, body mass index (BMI), fat percentage, and maximal strength were conducted at baseline, 10 weeks, and 20 weeks. A significant time effect was observed for all variables (p < 0.001), indicating improvements in both groups. However, group × time interactions revealed distinct adaptation patterns. The TradRT group exhibited greater reductions in body fat percentage and superior strength gains in bench press, leg press, shoulder press, and triceps pushdown, and abdominal strength. Conversely, the EMS group showed greater reductions in body weight and BMI. No significant interaction effect was observed for biceps curl strength. Both EMS and TradRT were effective in improving strength and body composition, but TradRT led to greater strength development and fat reduction, while EMS was more effective for weight and BMI reduction.

Conclusions

These findings suggest that EMS may serve as a viable alternative for individuals unable to engage in high-load resistance training, whereas TradRT remains superior for maximizing strength and fat loss.
目的肌电刺激(EMS)和传统阻力训练(TradRT)是目前广泛应用的提高肌力和肌体成分的方法。然而,采用多周纵向设计的比较研究仍然有限。本研究旨在探讨20周的EMS与TradRT对体力活动成年人身体成分和力量表现的影响。方法46例患者随机分为EMS组(n = 22)和TradRT组(n = 24)。EMS组每周进行两次25分钟的全身EMS训练,而TradRT组每周进行两次90分钟的全身阻力训练。结果在基线、10周和20周进行体重、体重指数(BMI)、脂肪百分比和最大力量的评估。所有变量均观察到显著的时间效应(p <;0.001),表明两组患者均有改善。然而,组×时间相互作用显示出不同的适应模式。TradRT组表现出更大的体脂率降低,在卧推、腿推、肩推、三头肌俯卧撑和腹部力量方面的力量增加。相反,EMS组的体重和身体质量指数下降幅度更大。对肱二头肌弯曲强度没有观察到显著的相互作用效应。EMS和TradRT在改善力量和身体成分方面都有效,但TradRT在力量发展和脂肪减少方面更有效,而EMS在体重和BMI降低方面更有效。这些研究结果表明,EMS可能是无法进行高负荷阻力训练的个体的可行替代方案,而TradRT在最大限度地增强力量和减少脂肪方面仍然优越。
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引用次数: 0
Enhancing cognitive function through blood flow restriction: An effective resistance exercise modality for middle-aged women 通过限制血流增强认知功能:一种有效的中年妇女抗阻运动方式
IF 2.4 2区 医学 Q2 SPORT SCIENCES Pub Date : 2025-10-01 Epub Date: 2025-08-12 DOI: 10.1016/j.jesf.2025.08.002
Dohyeon Lee , Kyeongho Byun , Sewon Lee

Purpose

Cognitive decline progresses more rapidly in women than in men, with a higher prevalence of neurodegenerative diseases observed in females. Exercise has been shown to enhance cognitive function through the upregulation of neurotrophic factors such as brain-derived neurotrophic factor (BDNF), vascular endothelial growth factor (VEGF) and insulin-like growth factor-1 (IGF-1). However, high-load resistance exercise may not be suitable for all populations, particularly middle-aged women. Low-load resistance exercise with blood flow restriction (LLBFR) has emerged as an effective alternative. This study investigated the acute effects of LLBFR on neurotrophic factors and cognitive function in middle-aged women.

Methods

Fifteen healthy middle-aged women completed a randomized crossover trial involving four conditions: control (CON), low-load resistance exercise (LLRE), LLBFR, and moderate-load resistance exercise (MLRE). Cognitive function was assessed before and after each session using the color-word matching Stroop task (CWST). Blood samples were analyzed for serum levels of BDNF, VEGF, and IGF-1, and lactate concentrations were measured to evaluate metabolic responses.

Results

Only the LLBFR condition showed significant improvements in CWST reaction time (p = 0.002) with no changes in error rates, indicating enhanced cognitive performance. Serum BDNF and VEGF levels increased significantly following both LLBFR (p < 0.001, p = 0.014, respectively) and MLRE (p < 0.001, p = 0.004, respectively), whereas IGF-1 levels remained unchanged across conditions. Increases in lactate concentrations were positively correlated with changes in BDNF and VEGF (p < 0.001 for both), but not with IGF-1.

Conclusion

A single session of LLBFR improved cognitive function and upregulated neurotrophic factors, particularly BDNF and VEGF, in middle-aged women. These findings suggest that LLBFR may be an effective intervention for promoting cognitive health in this population.
目的:女性认知能力下降的进展比男性更快,女性神经退行性疾病的患病率更高。运动已被证明可以通过上调脑源性神经营养因子(BDNF)、血管内皮生长因子(VEGF)和胰岛素样生长因子-1 (IGF-1)等神经营养因子来增强认知功能。然而,高负荷阻力运动可能并不适合所有人群,尤其是中年女性。低负荷阻力运动与血流限制(LLBFR)已成为一种有效的替代方案。本研究探讨了LLBFR对中年妇女神经营养因子和认知功能的急性影响。方法15名健康中年妇女完成了一项随机交叉试验,包括4种条件:对照组(CON)、低负荷阻力运动(LLRE)、低负荷阻力运动(llfr)和中负荷阻力运动(MLRE)。认知功能在每次会话前后使用色词匹配Stroop任务(CWST)进行评估。分析血液样本的血清BDNF、VEGF和IGF-1水平,并测量乳酸浓度以评估代谢反应。结果只有LLBFR组在CWST反应时间上有显著改善(p = 0.002),而错误率没有变化,表明认知能力有所提高。在LLBFR (p < 0.001, p = 0.014)和MLRE (p < 0.001, p = 0.004)后,血清BDNF和VEGF水平均显著升高,而IGF-1水平在各条件下保持不变。乳酸浓度的增加与BDNF和VEGF的变化呈正相关(两者p <; 0.001),但与IGF-1无关。结论:单次LLBFR可改善中年妇女的认知功能,上调神经营养因子,特别是BDNF和VEGF。这些发现表明,LLBFR可能是促进这一人群认知健康的有效干预措施。
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引用次数: 0
Impact of training volume settings between unilateral training and bilateral training on athletic performance: A systematic review and meta-analysis 单侧训练和双侧训练之间的训练量设置对运动成绩的影响:系统回顾和荟萃分析
IF 2.4 2区 医学 Q2 SPORT SCIENCES Pub Date : 2025-10-01 Epub Date: 2025-06-12 DOI: 10.1016/j.jesf.2025.06.003
Meiling Tao , George P. Nassis , Yuou Song , Mingyue Yin , Chenwen Zhu , Mengde Lyu , Zhili Chen , Yuming Zhong , Chris Bishop , Yongming Li
<div><h3>Background</h3><div>The unilateral/bilateral dimension refers to whether an action is performed by one side of the body alone or involves both sides simultaneously. Unilateral training (UT) and bilateral training (BT) have been shown to enhance athletic performance. However, there are differences in training volume settings between unilateral and bilateral training, making it essential to understand their characteristics for optimizing training protocols and improving competitive level.</div></div><div><h3>Objective</h3><div>This systematic review aimed to: 1) explore the effects of training volume settings between unilateral training and bilateral training on improvements in athletic performance (muscle strength, jump performance, sprint time, and change of direction time), and 2) investigate the moderating effects on testing metrics, training frequency, and training protocol on athletic performance.</div></div><div><h3>Methods</h3><div>Searches were conducted in PubMed, Medline, Cochrane Library, EBSCOhost, and Web of Science (Core Collection) on June 5, 2024, and updated on April 17, 2025. Included studies were randomized controlled trials that investigated the effects of UT versus BT on athletic performance in athlete. Pooled effects for each outcome were summarized using Standardized Mean Difference [Hedges' g (g)] through a three-level meta-analysis model, and subgroup analyses were used to explore moderators. The certainty of evidence was assessed using the GRADE approach.</div></div><div><h3>Results</h3><div>A total of nine high-quality randomized controlled trials were included, involving 225 athletes. The results showed that there was no significant difference in improving athletic performance whether the training volume of UT and BT was the same (g = 0.20 [-1.56, 1.15], I<sup>2</sup>-2 = 77.8 %; I<sup>2</sup>-3 = 0.0 %, low GRADE) or when the UT volume was twice that of BT (−0.04 [-0.14, 0.06], I<sup>2</sup>-2 = 93.8 %; I<sup>2</sup>-3 = 0.0 %, moderate GRADE). When the training volumes of UT and BT were the same, the impact on athletic performance was not significantly moderated by test items, training frequency, or training protocols. Neither unilateral test metrics (g = −0.84) nor bilateral test metrics (g = −0.90) showed significant improvement. There was no significant difference between training twice a week (g = −0.16) and training three times a week (g = −0.19). Similarly, there was no significant difference between conducting plyometric training (g = −0.16) and another instance of plyometric training (g = −0.19). When the UT volume was twice that of BT, it might be significantly moderated by test items, but training frequency and training protocols were likely not significant moderators. Unilateral test metrics (g = −0.39) and bilateral test metrics (g = 0.64) both showed significant improvements. There was still no significant difference between training twice a week (g = −0.14) and training three times a week (g = 0
单侧/双侧维度指的是一个动作是由身体的一侧单独完成还是同时涉及到两侧。单侧训练(UT)和双侧训练(BT)已被证明可以提高运动成绩。然而,单侧训练和双侧训练在训练量设置上存在差异,了解它们的特点对于优化训练方案和提高竞技水平至关重要。目的:探讨单侧训练和双侧训练的训练量设置对运动员运动成绩(肌肉力量、跳跃成绩、冲刺时间和转向时间)的影响;研究测试指标、训练频率和训练方案对运动员运动成绩的调节作用。方法于2024年6月5日在PubMed、Medline、Cochrane Library、EBSCOhost和Web of Science (Core Collection)中进行检索,并于2025年4月17日更新。纳入的研究是随机对照试验,研究UT与BT对运动员运动成绩的影响。通过三水平荟萃分析模型,使用标准化平均差异[Hedges' g (g)]总结每个结果的合并效应,并使用亚组分析来探索调节因子。使用GRADE方法评估证据的确定性。结果共纳入9项高质量随机对照试验,涉及225名运动员。结果表明,无论训练量是否相同,UT和BT对运动成绩的提高均无显著差异(g = 0.20 [-1.56, 1.15], I2-2 = 77.8%;I2-3 = 0.0%,低分级)或当UT体积为BT的两倍时(- 0.04 [-0.14,0.06],I2-2 = 93.8%;I2-3 = 0.0%,中等等级)。当UT和BT的训练量相同时,测试项目、训练频率或训练方案对运动成绩的影响没有显著调节。单侧测试指标(g = - 0.84)和双侧测试指标(g = - 0.90)均未显示显著改善。每周训练两次(g = - 0.16)和每周训练三次(g = - 0.19)之间无显著差异。同样,在进行增强式训练(g = - 0.16)和另一次增强式训练(g = - 0.19)之间也没有显著差异。当UT量是BT量的两倍时,测试项目可能会显著调节UT量,但训练频率和训练方案可能不会显著调节UT量。单侧测试指标(g = - 0.39)和双侧测试指标(g = 0.64)均显示出显著改善。每周训练两次(g = - 0.14)与每周训练三次(g = 0.13)之间仍无显著差异。此外,在进行增强训练(g = - 0.01)和另一次增强训练(g = - 0.21)之间没有显著差异。结论单侧训练和双侧训练之间的训练量设置对运动员的运动成绩没有显著影响。测试指标可能是重要的调节因素,而训练频率和训练协议可能不是重要的调节因素。普洛斯彼罗registrationCRD42024545511。
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引用次数: 0
The proportion of moderate-to-vigorous-intensity physical activity to total volume of physical activity correlates with decreased risk of possible sarcopenia: A prospective cohort study 一项前瞻性队列研究:中等至高强度体力活动占体力活动总量的比例与可能的肌肉减少症风险降低相关
IF 2.4 2区 医学 Q2 SPORT SCIENCES Pub Date : 2025-10-01 Epub Date: 2025-11-04 DOI: 10.1016/j.jesf.2025.11.003
Xiuguo Ge , Xiaoxiang Shen , Xiaoguang Zhao

Objectives

Physical activity (PA) intensity is a critical factor in managing chronic diseases. However, a significant gap remains regarding how the relative proportion of moderate-to-vigorous PA (MVPA) within total PA volume specifically influences sarcopenia risk, particularly as evidenced by longitudinal data. This study therefore specifically aimed to investigate the longitudinal association between the MVPA fraction and the incidence of possible sarcopenia (PS).

Methods

We conducted a prospective cohort study of 4,215 middle-aged and older individuals from the first wave in 2011 and the third wave in 2015 of the China Health and Retirement Longitudinal Study. We used a Chinese version of the International Physical Activity Questionnaire to assess PA. Muscle strength and physical performance were used to determine PS in accordance with the Asian Working Group for Sarcopenia 2019. The association between the proportion of MVPA to total PA volume and the risk of PS was tested using robust Poisson regression analysis.

Results

In comparison to no activity, the 0%, 1%–33%, 34%–66%, and 67%–100% of MVPA were linked to 11% (aRR = 0.89, 95 % CI = 0.74, 1.08), 26% (aRR = 0.74, 95 % CI = 0.57, 0.96), 20% (aRR = 0.80, 95 % CI = 0.66, 0.98), and 33% (aRR = 0.67, 95 % CI = 0.56, 0.83) decreases in the risk of PS, respectively. Subgroup analyses by sex and age revealed that the inverse association between MVPA proportion and PS risk remained significant specifically among women and older adults. A sensitivity analysis confirmed the inverse association between MVPA proportion and PS risk.

Conclusions

The study findings suggest that middle-aged and older adults with a greater proportion of MVPA to total volume of PA may have a decreased risk of PS, and the correlation is affected by age and sex.
目的体育活动(PA)强度是治疗慢性疾病的关键因素。然而,关于中度至剧烈PA (MVPA)在总PA容积中的相对比例如何具体影响肌肉减少症风险,特别是纵向数据所证明的,仍然存在重大差距。因此,本研究专门旨在调查MVPA分数与可能的肌肉减少症(PS)发生率之间的纵向关联。方法对2011年第一波和2015年第三波中国健康与退休纵向研究的4215名中老年个体进行前瞻性队列研究。我们使用中文版的国际体育活动问卷来评估PA。根据2019年亚洲肌肉减少症工作组的规定,使用肌肉力量和身体表现来确定PS。MVPA占总PA容积的比例与PS风险之间的关系采用稳健泊松回归分析进行检验。结果与不活动组相比,MVPA组0%、1% ~ 33%、34% ~ 66%和67% ~ 100%分别使PS风险降低11% (aRR = 0.89, 95% CI = 0.74, 1.08)、26% (aRR = 0.74, 95% CI = 0.57, 0.96)、20% (aRR = 0.80, 95% CI = 0.66, 0.98)和33% (aRR = 0.67, 95% CI = 0.56, 0.83)。性别和年龄的亚组分析显示,MVPA比例与PS风险之间的负相关仍然显著,特别是在女性和老年人中。敏感性分析证实MVPA比例与PS风险呈负相关。结论中老年人MVPA占PA总量的比例越大,患PS的风险越低,且相关性受年龄和性别的影响。
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引用次数: 0
Relationship between cardiorespiratory fitness and arterial health in young-, and middle-age women: A mediation effect of body composition 中青年女性心肺健康与动脉健康的关系:身体成分的中介作用
IF 2.4 2区 医学 Q2 SPORT SCIENCES Pub Date : 2025-10-01 Epub Date: 2025-07-16 DOI: 10.1016/j.jesf.2025.07.004
Jitanan Laosiripisan , Napasakorn Chuensiri , Prin Ongkeaw , Thanonwat Sriputsayathanoth , Sawitree Poonpetpradab , Pornpicha Narmgate
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引用次数: 0
期刊
Journal of Exercise Science & Fitness
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