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The prevalence and risk factors of suicidal behavior among people who use drugs and alcohol: A comprehensive systematic review. 吸毒和酗酒人群自杀行为的流行程度和危险因素:一项全面的系统综述。
IF 1.2 4区 医学 Q4 SUBSTANCE ABUSE Pub Date : 2026-01-13 DOI: 10.1080/15332640.2026.2613732
Yamunaa Sai Mohana Rao, Jasmin Jalil, Mohammad Farris Iman Leong Bin Abdullah

There are various studies which investigated the prevalence and risk of suicide among people who use substance. However, there is lack of a systematic review to intensively summarize and analyze the findings of these studies in order to deduce important clinical implications. Hence, this systematic review aimed to explore the prevalence, risk and protective factors of suicidal behavior among people who use drugs and alcohol. A comprehensive search for research articles from 1980 to 2025 was carried out through major databases, data extraction and assessment of quality of the selected research articles were performed by two authors. A total of 26 articles were selected for review. The prevalence of suicidal ideation among substance and alcohol users ranged from 9.9 to 50.7%, while the prevalence of suicidal attempt ranged from 2.7 to 47%. The common risk factors of suicidal behavior among people who use drugs and alcohol were history of dysphoric-mixed or depressive disorders, younger age (<30 years old or 30-39 years), increase number of drug use, polydrug use or concurrent use of more than one substance, history of personality disorders or traits, history of previous or repeated suicidal attempts, and female gender. Those with risk factors of suicidal behavior must be thoroughly monitored, and effective psychosocial intervention for managing the modifiable risk factors must be implemented.

有各种各样的研究调查了吸毒人群中自杀的流行程度和风险。然而,缺乏系统的综述来深入总结和分析这些研究的发现,以推断重要的临床意义。因此,本系统综述旨在探讨吸毒和酗酒人群自杀行为的患病率、风险和保护因素。通过主要数据库对1980 - 2025年的研究文章进行了全面检索,由两位作者对所选研究文章进行了数据提取和质量评估。共选择26篇文章进行综述。药物和酒精使用者中自杀意念的流行率为9.9%至50.7%,而自杀企图的流行率为2.7%至47%。在使用药物和酒精的人群中,自杀行为的常见危险因素是有躁郁症或抑郁症病史、年龄较小(
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引用次数: 0
Pathways from racial/ethnic discrimination experience to cannabis use intentions: a longitudinal study of the mediating roles of perceived accessibility and harm among preteens. 从种族/民族歧视经验到大麻使用意图的途径:对青少年感知可及性和伤害中介作用的纵向研究。
IF 1.2 4区 医学 Q4 SUBSTANCE ABUSE Pub Date : 2026-01-13 DOI: 10.1080/15332640.2025.2612339
Tzung-Shiang Ou, Su-Wei Wong, Meng Yang, Hsien-Chang Lin

This study aimed to explore potential mediation pathways between racial/ethnic discrimination experience and cannabis use intention through perceived cannabis accessibility and then perceived harm. Preteens (N = 2,690, ages 9-13) from the Adolescent Brain Cognitive Development Study (Release 4.0) were included. Structural equation modeling was conducted. Experiencing racial/ethnic discrimination was associated with higher cannabis use intention (β = 0.068, p < 0.05). Preteens who experienced racial/ethnic discrimination were more likely to perceive cannabis as more accessible (β = 0.134, p < 0.05), resulting in lower perceived harm (β=-0.123, p < 0.001), which subsequently increased cannabis use intention (β=-0.085, p < 0.001). These results emphasize the need for interventions to address discrimination-related trauma in preteens.

本研究旨在通过感知大麻可及性,进而感知伤害,探索种族/民族歧视经历与大麻使用意图之间的潜在中介途径。纳入青少年大脑认知发展研究(Release 4.0)的青春期前儿童(N = 2690,年龄9-13岁)。进行了结构方程建模。经历过种族/民族歧视与更高的大麻使用意愿相关(β = 0.068, p β= 0.134, p β=-0.123, p β=-0.085, p β=-0.085)
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引用次数: 0
A new integrated intervention model in Iran: How it affects homeless mothers with substance use disorder and their children? 伊朗的一种新的综合干预模式:它如何影响有物质使用障碍的无家可归的母亲及其子女?
IF 1.2 4区 医学 Q4 SUBSTANCE ABUSE Pub Date : 2026-01-12 DOI: 10.1080/15332640.2025.2611346
Marzyieh Hamzehzadeh, Amir Moghanibashi-Mansourieh, Faezeh Atefi, Monire Balochi, Mohammad Jafarian, Abbas Deilamizade

Introduction: The number of women with substance use disorder has been growing in Iran. The study aims investigation of a new integrated intervention for women and mothers in Tehran, Iran.

Method: This research employed an explanatory sequential mixed-methods design within a three-year cohort survey, investigated the effectiveness of an integrated intervention model on treatment retention and quality of life of mothers and pregnant women with substance use disorder. The data were collected through pre-post-test using questionnaires, focus group discussions guided by semi-structured interviews, and rapid multi-purpose urine test. The tools used are a ten-panel urine drug test and a 26-item WHOQOL-BREF. For the qualitative phase, these focus group discussions were carried out. 53 Participants met the inclusion criteria and entered the research.

Results: The findings show 60.4% of clients retained in treatment. While the overall quality of life did not show a statistically significant increase (p = 0.622, d = 0.13), significant improvements were observed in specific subsets of quality of life: Physical Health (MD = 9.811, 95% CI = [0.374, 19.247], p = 0.042, d = 0.59), Social Relations (MD = 9.729, 95% CI = [0.721, 18.737], p = 0.035, d = 0.61) and environmental (MD = 12.216, 95% CI = [2.688, 21.745], p = 0.013, d = 0.72). Two main themes of 'treatment aspects' and 'social aspects' in the model were identified as the main factors affecting the effectiveness of the treatment classified under different types of social support.

Conclusion: This study demonstrates that a comprehensive integrated intervention model effectively addresses the complex and specific needs of women in recovery. The treatment and social support components of this approach emerged as pivotal components, playing a critical role in meeting these multidimensional needs.

在伊朗,有物质使用障碍的妇女人数一直在增长。这项研究旨在调查伊朗德黑兰妇女和母亲的一种新的综合干预措施。方法:本研究采用解释性序贯混合方法设计,在一项为期三年的队列调查中,研究了一种综合干预模型对物质使用障碍母亲和孕妇治疗保留和生活质量的有效性。通过问卷调查法、半结构化访谈指导下的焦点小组讨论法和快速多用途尿检法收集数据。所使用的工具是10项尿检和26项WHOQOL-BREF。在定性阶段,进行了这些焦点小组讨论。53名符合纳入标准的参与者进入研究。结果:60.4%的患者坚持治疗。虽然总体生活质量没有统计学意义上的显著提高(p = 0.622, d = 0.13),但在生活质量的特定亚组中有显著改善:身体健康(MD = 9.811, 95% CI = [0.374, 19.247], p = 0.042, d = 0.59)、社会关系(MD = 9.729, 95% CI = [0.721, 18.737], p = 0.035, d = 0.61)和环境(MD = 12.216, 95% CI = [2.688, 21.745], p = 0.013, d = 0.72)。模型中的“治疗方面”和“社会方面”两个主题被确定为影响治疗有效性的主要因素,分为不同类型的社会支持。结论:本研究表明,综合干预模式能有效解决妇女康复过程中复杂而特殊的需求。这种方法的治疗和社会支持部分成为关键部分,在满足这些多方面需求方面发挥着关键作用。
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引用次数: 0
Adverse childhood experiences and spiritual well-being: Serial mediation through meaning-based coping and substance misuse. 不良童年经历与精神健康:透过意义因应与物质滥用的系列中介作用。
IF 1.2 4区 医学 Q4 SUBSTANCE ABUSE Pub Date : 2026-01-09 DOI: 10.1080/15332640.2025.2611125
Saide Umut Zeybek Çaktı, Hacer Yıldırım Kurtuluş

Adverse childhood experiences (ACE) can profoundly affect individuals' psychological functioning and internal meaning systems in later life. In this interaction, the individual's coping style and tendency toward harmful habits may play a decisive role. This study examined the association between adverse childhood experiences and spiritual well-being and tested the serial mediating roles of meaning-based coping and substance misuse in this association. The study sample consisted of a total of 501 volunteer participants, including 247 women (49.3%) and 254 men (50.7%). Participants' ages ranged from 18 to 47 years (M = 22.46 years, SD = 4.51). The study employed a cross-sectional descriptive design based on structural equation modeling. In addition to structural equation modeling, bootstrapping analysis was also performed. The results of the study indicate that the relationship between ACEs and spiritual well-being is serially mediated by meaning-based coping and substance misuse (β = -0.076, 95% CI = -0.125, -0.033; p < .05). The findings provide a deeper understanding of the relationship between ACEs and spiritual well-being and are discussed in light of possible explanations and limitations.

童年不良经历会对个体日后的心理功能和内在意义系统产生深远的影响。在这种相互作用中,个体的应对方式和不良习惯倾向可能起决定性作用。本研究考察了童年不良经历与精神幸福感的关系,并检验了意义型应对和物质滥用在这一关系中的系列中介作用。研究样本由501名志愿者组成,其中247名女性(49.3%)和254名男性(50.7%)。参与者年龄从18岁到47岁不等(M = 22.46岁,SD = 4.51)。本研究采用基于结构方程模型的横断面描述性设计。除结构方程建模外,还进行了自举分析。研究结果表明,基于意义的应对和药物滥用在ace与精神幸福感的关系中起着连续中介作用(β = -0.076, 95% CI = -0.125, -0.033; p < 0.05)。研究结果为ace与精神健康之间的关系提供了更深入的理解,并根据可能的解释和局限性进行了讨论。
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引用次数: 0
Investigating the landscape of cognitive enhancers use among future physicians: Findings from a developing Middle Eastern country. 调查未来医生使用认知增强剂的情况:来自中东一个发展中国家的发现。
IF 1.2 4区 医学 Q4 SUBSTANCE ABUSE Pub Date : 2026-01-04 DOI: 10.1080/15332640.2025.2611432
Ahmad T Qatawneh, Fatima Ryalat, Hana Erekat, Baker Shiha, Hadeel Abuatiyeh, Ali Almahrook, Saif Aldeen AlRyalat

Cognitive enhancers (CE) are substances frequently used to enhance cognitive capabilities, especially in demanding environments, such as medical schools. Accordingly, this study aimed to investigate students' knowledge, attitudes toward, and usage of CEs. Data was collected from 350 medical students through an online questionnaire. Around (22.3%) of participants were found to be users of prescription pills as CEs, with beta-blockers and nasal decongestants being the most frequently abused substances (16.3%). Lifetime usage of prescription pills as CEs was associated with usage of natural supplements (p < 0.05, OR: 2.01), tobacco smoking (p < 0.05, OR: 2.79) and low concentration rating (p < 0.05, OR: 0.66). The majority (66.9%) first heard about CEs from the internet or their family and friends. While around (38%) considered using CEs to improve their attention and concentration, around (35.1%) refused to due to concerns regarding their safety. Our study has shown that Jordanian medical students use cognitive enhancers in their various forms, including psychostimulant drugs. However, given their unproven efficacy, safety and possible ethical and public health implications of their usage, concerns arise as these students will become medical practitioners and in charge of drug prescriptions. Accordingly, this should prompt policymakers to implement educational initiatives to spread awareness.

认知增强剂(CE)是经常用于增强认知能力的物质,特别是在苛刻的环境中,如医学院。因此,本研究旨在调查学生对消费语言的认知、态度和使用情况。通过在线问卷调查收集了350名医学生的数据。大约(22.3%)的参与者被发现使用处方药作为ce, β受体阻滞剂和鼻减充血剂是最常被滥用的物质(16.3%)。终生使用处方药作为ce与使用天然补充剂相关(p pp
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引用次数: 0
Contexts of drinking and cannabis use by Whites and Hispanics in California. 加州白人和西班牙裔的饮酒和大麻使用情况。
IF 1.2 4区 医学 Q4 SUBSTANCE ABUSE Pub Date : 2026-01-02 DOI: 10.1080/15332640.2025.2576728
Raul Caetano, M J Paschall, Patrice A C Vaeth, Zoe Kaplan

This study examines the contexts in which alcohol and cannabis are used among White and Hispanic co-users in 40 selected cities in California. Data were obtained from a household sample of 1,069 adults aged 21 to 49, collected via an online standardized questionnaire. Alcohol and cannabis use occurred mostly in two primary settings: at home alone or with family and at home with friends. Controlled analyses identified distinct correlates associated with each consumption context. However, race/ethnicity and co-use status (concurrent vs. simultaneous use) did not have statistically significant effects in any drinking or cannabis use setting. While context related differences between White and Hispanic co-users of alcohol and cannabis were minimal, it would be premature to assume that policies to regulate context use, especially public access contexts, would be equally effective across both groups. Although their epidemiological profiles appear similar, tailored intervention strategies-differing in content, format, delivery, and implementation-may be necessary to maximize effectiveness.

本研究调查了加州40个选定城市中白人和西班牙裔共同使用者使用酒精和大麻的情况。数据来自1069名年龄在21岁至49岁之间的成年人的家庭样本,通过在线标准化问卷收集。酒精和大麻的使用主要发生在两种情况下:独自在家或与家人在一起,以及与朋友在一起。对照分析确定了与每个消费环境相关的不同相关性。然而,种族/民族和共同使用状态(同时使用与同时使用)在任何饮酒或大麻使用环境中都没有统计学上的显著影响。虽然白人和西班牙裔酒精和大麻共同使用者之间与环境有关的差异很小,但假设管制环境使用的政策,特别是公共获取环境的政策,对两个群体同样有效,还为时过早。尽管他们的流行病学概况似乎相似,但可能需要量身定制的干预策略——在内容、形式、交付和实施方面有所不同——以实现效果最大化。
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引用次数: 0
Prevalence and determinants of alcohol use Disorder among Kachin adults: A cross-sectional study of behavioral, psychosocial and marketing influences. 克钦成年人酒精使用障碍的患病率和决定因素:行为、社会心理和市场影响的横断面研究
IF 1.2 4区 医学 Q4 SUBSTANCE ABUSE Pub Date : 2026-01-02 DOI: 10.1080/15332640.2025.2611119
L Kum Ja, Kaung Myat Soe, Wor Mi Thi, Kyaw Min Htike, Roshan Kumar Mahato

Alcohol Use Disorder (AUD) is a significant global public health issue, contributing to high rates of morbidity, mortality and socio-economic disruption. In Myanmar particularly in border regions like Kachin State, AUD prevalence and its associated determinants remain poorly understood. This study aimed to estimate the prevalence of AUD among adult males in Kachin State and to identify behavioral, psychosocial and marketing-related risk factors. A cross-sectional study was conducted in three purposively selected townships of Kachin State. A total of 428 adult males (≥18 years) were selected using multistage random sampling. Data were collected using a structured questionnaire incorporating the Alcohol Use Disorder Identification Test (AUDIT) and defined as an AUDIT score ≥8. Descriptive statistics and multiple logistic regression analyses were performed. The prevalence of Alcohol Use Disorder was 39.95% (95% CI: 35.40-44.68). Key factors associated with AUD were ease of access to alcohol (AOR: 4.44, 95% CI: 2.51-7.85), early initiation before age 18 (AOR: 2.33, 95% CI: 1.23-4.40), smoking while drinking (AOR: 1.90, 95% CI: 1.19-3.03), drink-driving history (AOR: 1.67, 95% CI: 1.04-2.71), reporting alcohol-related health issues (AOR: 2.63, 95% CI: 1.63-4.25) and depression (AOR: 1.52, 95% CI: 1.14-2.03). Alcohol Use Disorder remains a pressing public health concern with multiple behavioral, psychosocial and environmental determinants. The strong associations with early initiation, risk behaviors, poor mental health and low awareness of harm indicate the need for early prevention, mental health support and public education. Interventions should also address alcohol accessibility and regulate marketing to mitigate the growing burden of AUD.

酒精使用障碍(AUD)是一个重大的全球公共卫生问题,导致高发病率、高死亡率和社会经济混乱。在缅甸,特别是在克钦邦等边境地区,人们对澳元患病率及其相关决定因素仍然知之甚少。本研究旨在估计克钦邦成年男性的AUD患病率,并确定行为、社会心理和市场相关的风险因素。在克钦邦有目的选择的三个乡镇进行了横断面研究。采用多阶段随机抽样方法,选取年龄≥18岁的成年男性428人。数据收集采用包含酒精使用障碍识别测试(AUDIT)的结构化问卷,并定义为AUDIT得分≥8。进行描述性统计和多元逻辑回归分析。酒精使用障碍患病率为39.95% (95% CI: 35.40-44.68)。与AUD相关的关键因素是容易接触酒精(AOR: 4.44, 95% CI: 2.51-7.85)、18岁前早期接触酒精(AOR: 2.33, 95% CI: 1.23-4.40)、饮酒时吸烟(AOR: 1.90, 95% CI: 1.19-3.03)、酒驾史(AOR: 1.67, 95% CI: 1.04-2.71)、报告与酒精相关的健康问题(AOR: 2.63, 95% CI: 1.63-4.25)和抑郁症(AOR: 1.52, 95% CI: 1.14-2.03)。酒精使用障碍仍然是一个紧迫的公共卫生问题,涉及多种行为、社会心理和环境决定因素。与早期开始、危险行为、心理健康状况不佳和对危害认识不足的强烈关联表明,需要进行早期预防、心理健康支持和公共教育。干预措施还应解决酒精可及性和规范营销,以减轻澳大利亚日益增长的负担。
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引用次数: 0
Family history of substance problems among African Americans: Associations with drug use, drug use disorder, and prescription drug misuse. 非裔美国人的药物问题家族史:药物使用、药物使用障碍和处方药滥用的关联。
IF 1.2 4区 医学 Q4 SUBSTANCE ABUSE Pub Date : 2026-01-01 Epub Date: 2024-03-26 DOI: 10.1080/15332640.2024.2331108
Rebecca Mahrs-Gould, Nancy Jallo, Dace Svikis, Suzanne Ameringer, Jo Robins, R K Elswick

A family history of substance problems is a well-known risk factor for substance use and use disorders; however, much of this research has been conducted in studies with predominantly White subjects. The aim of this study was to examine the associations between family history density of substance problems and drug use, risk for drug use disorder, and prescription drug misuse in a sample of African American adults. Results indicate that family history density of substance problems increased the risk for all drug outcomes in the full sample. However, when subgroup analyses by gender were conducted, family history was not a risk factor among men for prescription drug misuse.

众所周知,有药物问题的家族史是导致药物使用和使用障碍的一个风险因素;然而,这方面的大部分研究都是针对以白人为主的受试者进行的。本研究旨在研究非裔美国成年人样本中,药物问题家族史密度与药物使用、药物使用障碍风险和处方药滥用之间的关联。结果表明,在全部样本中,药物问题家族史密度增加了所有药物结果的风险。然而,在按性别进行分组分析时,家庭病史并不是男性滥用处方药的风险因素。
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引用次数: 0
"They either leave you or they get involved in it": Familial factors influencing drug use amongst Appalachian people. "他们要么离开你,要么卷入其中":影响阿巴拉契亚人吸毒的家庭因素。
IF 1.2 4区 医学 Q4 SUBSTANCE ABUSE Pub Date : 2026-01-01 Epub Date: 2024-02-22 DOI: 10.1080/15332640.2024.2316650
Cara L Sedney, Patricia Dekeseredy, Parker Anderson, Treah Haggerty

West Virginia, the only state entirely in Appalachia, is considered the epicenter of the opioid crisis. Children raised in families affected by opioid use disorder can develop their own substance use disorder later in life. The continuing opioid crisis coupled with social and health disparities suggest families in West Virginia are vulnerable to generational cycles of substance misuse. This qualitative study uses content analysis to present emergent themes discerned from participant interviews on the opioid epidemic and impacts of a restrictive opioid prescribing law in West Virginia. Participants in this study described how using opioids has impacted their lives, their family, and community. They recognized drug use was embedded along familial groups and influenced by significant others such as partners or peers. Parents described how children were a strong motivator for recovery and how they felt remorse for exposing their children to their drug use. This study highlights the importance of community engagement, parental support, and early identification of vulnerable young people to lessen the intergenerational continuance of substance use.

西弗吉尼亚州是唯一一个完全位于阿巴拉契亚地区的州,被认为是阿片类药物危机的中心。在受阿片类药物使用障碍影响的家庭中长大的孩子,日后也可能患上药物使用障碍。持续的阿片类药物危机加上社会和健康差异,表明西弗吉尼亚州的家庭很容易陷入药物滥用的世代循环。本定性研究采用内容分析法,介绍了从参与者访谈中发现的关于阿片类药物流行和西弗吉尼亚州阿片类药物限制性处方法影响的新主题。本研究的参与者描述了阿片类药物的使用如何影响了他们的生活、家庭和社区。他们认识到,吸毒与家庭关系密切,并受到伴侣或同龄人等重要他人的影响。家长们描述了子女如何成为他们康复的强大动力,以及他们如何为让子女接触到自己的吸毒行为而感到懊悔。这项研究强调了社区参与、父母支持以及及早识别易受影响的年轻人对减少药物使用代际延续的重要性。
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引用次数: 0
Technical and relational process in MI sessions with a sample of Hispanic/Latinx adults who engage in heavy drinking: A latent growth mediation model. 以酗酒的西班牙裔/拉美裔成年人为样本,研究多元智能课程中的技术和关系过程:潜在增长调解模型。
IF 1.2 4区 医学 Q4 SUBSTANCE ABUSE Pub Date : 2026-01-01 Epub Date: 2024-01-09 DOI: 10.1080/15332640.2024.2301718
Molly Magill, Victor Figuereo, David G Zelaya, Kristina Jackson, Suzanne M Colby, Christina S Lee

The current study tests the Motivational Interviewing (MI) technical and relational hypotheses in a sample of Hispanic/Latinx adults (N = 276) who engage in heavy alcohol consumption. MI causal theory hypothesizes that therapist use of MI consistent skills (i.e., technical hypothesis) and embodiment of the MI Spirit (i.e., relational hypothesis) will elicit client change talk, which is a putative mechanism of positive client outcome after the session. We tested these associations in a rigorous parallel process latent growth curve mediation modeling framework. The data are from a completed randomized clinical trial of a culturally-adapted (CAMI) versus un-adapted MI targeting hazardous alcohol use and consequences. Results. The unconditional growth models for the mediator (i.e., proportion of change talk relative to sustain talk) and two study outcomes (i.e., percent of heavy drinking days; alcohol-related consequences) showed a linear effect over a 12-month period with a slower rate of growth at later timepoints. Contrary to expectations, the latent growth mediation models did not show relationships between MI-consistent skills (i.e., technical predictor) or latent MI Spirit (i.e., relational indicator) and the slope factor for proportion change talk. The slope factor for proportion change talk was also not associated with the slope factors for percent heavy drinking and consequences over follow-up. Conclusions. In this novel population for MI process analysis, the technical and relational hypotheses were not supported. Studies that are exploratory may be needed to further investigate the causal model in populations that are not often represented in MI process research.

本研究以大量饮酒的西班牙裔/拉美裔成年人(N = 276)为样本,测试了动机访谈(MI)的技术假设和关系假设。动机访谈因果理论假设,治疗师使用动机访谈的一致技能(即技术假设)和动机访谈精神的体现(即关系假设)将引起客户的改变谈话,而这是客户在访谈后取得积极结果的一种假定机制。我们在一个严格的平行过程潜在增长曲线中介模型框架中测试了这些关联。数据来源于一项已完成的随机临床试验,该试验是针对危险饮酒及其后果的文化适应型(CAMI)与非适应型多元智能的对比。研究结果介导因素(即相对于持续谈话的改变谈话比例)和两个研究结果(即大量饮酒天数百分比;与酒精相关的后果)的无条件增长模型显示,在 12 个月的时间里,两者呈线性关系,而在较晚的时间点,两者的增长速度较慢。与预期相反,潜在增长中介模型并没有显示出多元智能一致性技能(即技术预测因子)或潜在多元智能精神(即关系指标)与比例变化谈话斜率因子之间的关系。比例变化谈话的斜率因子也与随访期间大量饮酒百分比和后果的斜率因子无关。结论。在这一新的多元智能过程分析人群中,技术假设和关系假设没有得到支持。可能需要进行探索性研究,以便在多元智能过程研究中不常见的人群中进一步研究因果模型。
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引用次数: 0
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Journal of Ethnicity in Substance Abuse
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