In this study, two Schiff bases namely (E,E)-N,N’-biphenyl-4-4’diylbis[1-(furan-2-yl)methanimine] (BEFu) and3-[(Z)-N(4’-aminobiphenyl-4yl)ethanimidoyl]-2-hydroy-6-methyl-4H-pyran-4-one (BEDh) have been synthesized and characterized using UV-visible, FTIR, and NMR techniques. The corrosion inhibition study of BEFu and BEDh was investigated for mild steel corrosion in 1M hydrochloric acid medium using weight loss method, potentiodynamic polarization, EIS techniques, and Density Functional Theory (DFT). The results showed that the inhibition efficiency increasing with concentration and revealing a mixed-type inhibitor of predominantly anodic type. To explain the inhibition abilities of those molecules adsorbed on the mild steel surface, quantum chemical calculations have been performed using DFT. The HOMO and LUMO energies were calculated to determine the global reactivity indexes. The experimental and theoretical results were in good agreement.
{"title":"SYNTHESIS, CHARACTERIZATION, CORROSION INHIBITION OF MILD STEEL BY TWO SCHIFF BASES IN HCL AND DENSITY FUNCTIONAL THEORY STUDIES","authors":"A. Madani, L. Sibous, E. Bentouhami","doi":"10.4314/JFAS.V13I2.13","DOIUrl":"https://doi.org/10.4314/JFAS.V13I2.13","url":null,"abstract":"In this study, two Schiff bases namely (E,E)-N,N’-biphenyl-4-4’diylbis[1-(furan-2-yl)methanimine] (BEFu) and3-[(Z)-N(4’-aminobiphenyl-4yl)ethanimidoyl]-2-hydroy-6-methyl-4H-pyran-4-one (BEDh) have been synthesized and characterized using UV-visible, FTIR, and NMR techniques. The corrosion inhibition study of BEFu and BEDh was investigated for mild steel corrosion in 1M hydrochloric acid medium using weight loss method, potentiodynamic polarization, EIS techniques, and Density Functional Theory (DFT). The results showed that the inhibition efficiency increasing with concentration and revealing a mixed-type inhibitor of predominantly anodic type. To explain the inhibition abilities of those molecules adsorbed on the mild steel surface, quantum chemical calculations have been performed using DFT. The HOMO and LUMO energies were calculated to determine the global reactivity indexes. The experimental and theoretical results were in good agreement.","PeriodicalId":15885,"journal":{"name":"Journal of Fundamental and Applied Sciences","volume":"13 1","pages":"864-891"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41334543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There is a growing concern about energy use in Algeria. With rapid building development programs and improvements of the living conditions, building sector is will continue to be a major energy end-user. Main energy needs in buildings are due to heating and/or cooling, depending on local climatic conditions and type of building. In this paper. The primary aim was to analyze in two aspects – heating load, and cooling load of individual house energy consumption in the major climatic zones in Algeria. The individual house used heating and cooling solar system. The system performance was simulated using TRNsys program. This solar heating and cooling system incorporates between 89 m2 and 170 m2 of flat plate double glazed solar collectors provide solar energy contribution during both the heating and the cooling seasons; between 13.28 kW and 25.11 KW single effect, water– lithium bromide (H2O/LiBr) absorption chiller, for space cooling and heating, this system is the smallest solar heating and cooling system in the world.
{"title":"NUMERICAL ANALYSIS OF AN INTEGRATED SOLAR COOLING AND HEATING SYSTEM IN INDIVIDUAL HOUSE IN DIFFERENT ALGERIAN CLIMATES","authors":"O. Halloufi, A. Kaabi, M. Chougui","doi":"10.4314/JFAS.V13I2.12","DOIUrl":"https://doi.org/10.4314/JFAS.V13I2.12","url":null,"abstract":"There is a growing concern about energy use in Algeria. With rapid building development programs and improvements of the living conditions, building sector is will continue to be a major energy end-user. Main energy needs in buildings are due to heating and/or cooling, depending on local climatic conditions and type of building. In this paper. The primary aim was to analyze in two aspects – heating load, and cooling load of individual house energy consumption in the major climatic zones in Algeria. The individual house used heating and cooling solar system. The system performance was simulated using TRNsys program. This solar heating and cooling system incorporates between 89 m2 and 170 m2 of flat plate double glazed solar collectors provide solar energy contribution during both the heating and the cooling seasons; between 13.28 kW and 25.11 KW single effect, water– lithium bromide (H2O/LiBr) absorption chiller, for space cooling and heating, this system is the smallest solar heating and cooling system in the world.","PeriodicalId":15885,"journal":{"name":"Journal of Fundamental and Applied Sciences","volume":"13 1","pages":"845-863"},"PeriodicalIF":0.0,"publicationDate":"2021-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41949435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of this work is the use of Amberlite IRN 150 resin in the removal of Cr(III) and Cr(VI) from tanning and chrome plating waste waters respectively. Removal experiments were carried out in batch. Kenitics and equilibrium studies were undertaken using various models. The obtained results show that the increase in pH implies an increase of Cr(III) removal in tanning water and a decrease of Cr(VI) removal in chrome plating water. In the two cases, the exchange kinetics is well described by the second order model. The removal of the two ions by IRN150 is not limited by intraparticular diffusion. The Freundlich isotherm is more suitable for describing Cr(III) removal in tanning water. However, in chrome plating water, Cr(VI) removal is better described by the Langmuir isotherm.
{"title":"Cr(III) and Cr(VI) REMOVAL FROM WASTE WATER BY AMBERLITE IRN150","authors":"N. Bounab, C. Boukhalfa","doi":"10.4314/JFAS.V13I2.9","DOIUrl":"https://doi.org/10.4314/JFAS.V13I2.9","url":null,"abstract":"The aim of this work is the use of Amberlite IRN 150 resin in the removal of Cr(III) and Cr(VI) from tanning and chrome plating waste waters respectively. Removal experiments were carried out in batch. Kenitics and equilibrium studies were undertaken using various models. The obtained results show that the increase in pH implies an increase of Cr(III) removal in tanning water and a decrease of Cr(VI) removal in chrome plating water. In the two cases, the exchange kinetics is well described by the second order model. The removal of the two ions by IRN150 is not limited by intraparticular diffusion. The Freundlich isotherm is more suitable for describing Cr(III) removal in tanning water. However, in chrome plating water, Cr(VI) removal is better described by the Langmuir isotherm.","PeriodicalId":15885,"journal":{"name":"Journal of Fundamental and Applied Sciences","volume":"13 1","pages":"784-796"},"PeriodicalIF":0.0,"publicationDate":"2021-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45452298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In Algeria, pulses are rain crops and are drought-prone during their breeding period, resulting in a loss of yield. To this end, four varieties of lentil are tested for their drought tolerance through bio-stress indicators in a field trial during the 2016/2017 crop year. Plants are grown under rained and irrigated conditions (irrigation + rainfall), from the "flowering" stage to the "filling of grains" stage. The results indicated that drought stress significantly decreased the relative water content (13.4%), leaf surfaces (32.21%), and grain yield of all genotypes tested (58.37%). The chemical composition of lentil seeds showed a reduction in starch content (4.41%) and an increase in protein content (32.21%). Potassium ions and Sodium ions were present at the highest and lowest concentrations (747.91ppm- 4.5ppm) in rainfall conditions, respectively, while Ca++, PO4-, and Mg++ concentrations were not affected by drought. In conclusion, the emphasis on bio-indicators of water stress tolerance at the reproductive period is of great importance in minimizing grain yield losses and the quality of seeds.
{"title":"CHARACTERIZATION OF SOME MORPHO-PHYSIOLOGICAL RESPONSES, SEED CHEMICAL COMPOSITION AND GRAIN YIELD IN LENTIL VARIETIES ( Lens culinaris Medik culinaris) UNDER IRRIGATED AND RAINFED CONDITIONS","authors":"F. Tahir, A. Hassani, W. Rezzoug","doi":"10.4314/JFAS.V13I2.10","DOIUrl":"https://doi.org/10.4314/JFAS.V13I2.10","url":null,"abstract":"In Algeria, pulses are rain crops and are drought-prone during their breeding period, resulting in a loss of yield. To this end, four varieties of lentil are tested for their drought tolerance through bio-stress indicators in a field trial during the 2016/2017 crop year. Plants are grown under rained and irrigated conditions (irrigation + rainfall), from the \"flowering\" stage to the \"filling of grains\" stage. The results indicated that drought stress significantly decreased the relative water content (13.4%), leaf surfaces (32.21%), and grain yield of all genotypes tested (58.37%). The chemical composition of lentil seeds showed a reduction in starch content (4.41%) and an increase in protein content (32.21%). Potassium ions and Sodium ions were present at the highest and lowest concentrations (747.91ppm- 4.5ppm) in rainfall conditions, respectively, while Ca++, PO4-, and Mg++ concentrations were not affected by drought. In conclusion, the emphasis on bio-indicators of water stress tolerance at the reproductive period is of great importance in minimizing grain yield losses and the quality of seeds.","PeriodicalId":15885,"journal":{"name":"Journal of Fundamental and Applied Sciences","volume":"13 1","pages":"797-815"},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42423656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this study an experimental design was employed to investigate the effects of different operating conditions on the removal of fluoride by electrocoagulation with aluminum electrodes. Box-Behnken design was then used for optimizing and modeling the electrocoagulation process and for evaluating the effects and interactions of variables: current density (i, A/m2), flow rate (Q, mL/min), and initial fluoride concentration (C0, mg/L). The proposed model fitted very well with the experimental data. R2 adjusted correlation coefficients (AdjR2: 0.98) for fluoride removal efficiency showed a high significance of the model. The model predicted for a maximum removal of fluoride (95.07%) at the optimum operating conditions (120 A/m2, 120 mL/min and 30 mg/L) after the EC process was 94.76% at the same optimum operating conditions.
{"title":"OPTIMISATION AND MODELING OF FLUORIDE REMOVAL BY ELECTROCOAGULATION IN A CONTINUOUS FLOW BIPOLAR REACTOR","authors":"T. Benderrah, M. Djedid, M. Naceur, M. Benalia","doi":"10.4314/JFAS.V13I2.8","DOIUrl":"https://doi.org/10.4314/JFAS.V13I2.8","url":null,"abstract":"In this study an experimental design was employed to investigate the effects of different operating conditions on the removal of fluoride by electrocoagulation with aluminum electrodes. Box-Behnken design was then used for optimizing and modeling the electrocoagulation process and for evaluating the effects and interactions of variables: current density (i, A/m2), flow rate (Q, mL/min), and initial fluoride concentration (C0, mg/L). The proposed model fitted very well with the experimental data. R2 adjusted correlation coefficients (AdjR2: 0.98) for fluoride removal efficiency showed a high significance of the model. The model predicted for a maximum removal of fluoride (95.07%) at the optimum operating conditions (120 A/m2, 120 mL/min and 30 mg/L) after the EC process was 94.76% at the same optimum operating conditions.","PeriodicalId":15885,"journal":{"name":"Journal of Fundamental and Applied Sciences","volume":"13 1","pages":"770-783"},"PeriodicalIF":0.0,"publicationDate":"2021-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45054015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Tiaret-Saida is a new high-speed railway under construction in northwestern Algeria. The main objective of this study is to map the shallow subsurface geological features and soil characterization. A geophysical tool comprising ground penetrating radar (GPR) has been applied for identifying the possible presence of cavities and fractures in the subsoil. GPR measurements were taken from a total of 24 profiles. The total length of the profiles was 240 m. The results of the GPR profiles obtained by two central frequencies 200 and 400 MHz indicate the existence of several anomalies that can be attributed to cavities and fractures in the bottom of several excavations, at depth ranging from 1 to 2.2 m. The interpreted results of GPR data were calibrated with the available lithological data from five boreholes drilled.
{"title":"APPLICATION OF GROUND PENETRATING RADAR (GPR) METHOD FOR THE CHARACTERIZATION OF SOIL NEAR TIARET (NORTH-WEST OF ALGERIA)","authors":"K. Hebbache, D. Boubaya","doi":"10.4314/JFAS.V13I2.6","DOIUrl":"https://doi.org/10.4314/JFAS.V13I2.6","url":null,"abstract":"The Tiaret-Saida is a new high-speed railway under construction in northwestern Algeria. The main objective of this study is to map the shallow subsurface geological features and soil characterization. A geophysical tool comprising ground penetrating radar (GPR) has been applied for identifying the possible presence of cavities and fractures in the subsoil. GPR measurements were taken from a total of 24 profiles. The total length of the profiles was 240 m. The results of the GPR profiles obtained by two central frequencies 200 and 400 MHz indicate the existence of several anomalies that can be attributed to cavities and fractures in the bottom of several excavations, at depth ranging from 1 to 2.2 m. The interpreted results of GPR data were calibrated with the available lithological data from five boreholes drilled.","PeriodicalId":15885,"journal":{"name":"Journal of Fundamental and Applied Sciences","volume":"13 1","pages":"724-739"},"PeriodicalIF":0.0,"publicationDate":"2021-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47363892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vegetation affects the urban microclimate in different ways, including shading, aspersing the humidity and controlling the wind velocity. In urban areas, microclimatic regulation depends on a number of features such as type and ratio of vegetation. This paper investigates the microclimatic regulation of palm trees in semi-arid environment during heat stress. El Nakhlette Street located in Guelma, Algeria has been selected to conduct the investigation, we measured air temperature, relative humidity and wind velocity during the hottest period of 2019.The study simulates four scenarios of El Nakhlette space in hot season with different ratio and type of vegetation using Envi-met model. The index PMV has been used to measure the heat stress levels. The findings show that palm trees as an evergreen type have the lesser microclimatic regulation and it is not the most suitable type to semi-arid environment.
{"title":"MICROCLIMATIC REGULATION OF PALM TREES IN SEMI-ARID ENVIRONMENT DURING HEAT STRESS","authors":"B. Sayad, D. Alkama","doi":"10.4314/JFAS.V13I2.4","DOIUrl":"https://doi.org/10.4314/JFAS.V13I2.4","url":null,"abstract":"Vegetation affects the urban microclimate in different ways, including shading, aspersing the humidity and controlling the wind velocity. In urban areas, microclimatic regulation depends on a number of features such as type and ratio of vegetation. This paper investigates the microclimatic regulation of palm trees in semi-arid environment during heat stress. El Nakhlette Street located in Guelma, Algeria has been selected to conduct the investigation, we measured air temperature, relative humidity and wind velocity during the hottest period of 2019.The study simulates four scenarios of El Nakhlette space in hot season with different ratio and type of vegetation using Envi-met model. The index PMV has been used to measure the heat stress levels. The findings show that palm trees as an evergreen type have the lesser microclimatic regulation and it is not the most suitable type to semi-arid environment.","PeriodicalId":15885,"journal":{"name":"Journal of Fundamental and Applied Sciences","volume":"13 1","pages":"694-707"},"PeriodicalIF":0.0,"publicationDate":"2021-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45043844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biometric systems are widely used in medium and low security applications. Verification systems based on the geometry of the hand utilize some geometrical characteristics of the hand including measurements of fingers, shape of the palm, etc. In this work, we have developed an unconstrained and contact-based hand geometry verification system, using a combination of length and width of fingers. New measurements at different points of fingers were introduced in this paper to improve the performance of the recognition of persons. A total of 135 hand images were enrolled in this study. The Euclidean distance was used as a similarity function for different values of threshold. The proposed method was compared to state-of-the-art approaches. The results obtained reveal the high performance of the proposed approach and outperformed the existing methods with an accuracy of Acc = 98.67%.
{"title":"BIOMETRIC VERIFICATION SYSTEM BASED ON HAND GEOMETRY","authors":"K. Harrar","doi":"10.4314/JFAS.V13I2.11","DOIUrl":"https://doi.org/10.4314/JFAS.V13I2.11","url":null,"abstract":"Biometric systems are widely used in medium and low security applications. Verification systems based on the geometry of the hand utilize some geometrical characteristics of the hand including measurements of fingers, shape of the palm, etc. In this work, we have developed an unconstrained and contact-based hand geometry verification system, using a combination of length and width of fingers. New measurements at different points of fingers were introduced in this paper to improve the performance of the recognition of persons. A total of 135 hand images were enrolled in this study. The Euclidean distance was used as a similarity function for different values of threshold. The proposed method was compared to state-of-the-art approaches. The results obtained reveal the high performance of the proposed approach and outperformed the existing methods with an accuracy of Acc = 98.67%.","PeriodicalId":15885,"journal":{"name":"Journal of Fundamental and Applied Sciences","volume":"13 1","pages":"816-844"},"PeriodicalIF":0.0,"publicationDate":"2021-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45113214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Onah, I. Ugwoke, U. J. Eze, H. C. Eze, S. Musa, S. Ndiana-Abasi, O. Okoli, I. E. Ekeh, A. Edet
The emergence of the deadly SARS-CoV-2, the etiologic agent of COVID-19 towards the end of the fourth quarter of 2019 has necessitated intensive research towards the development of drugs and vaccine that can combat the disease. Consequently, we conducted molecular docking of the e-Drug3D library using London dG and Affinity dG as scoring algorithms for common structural scaffolds in drug molecules with strong binding affinities towards SARS-CoV-2 Mpro. 15 drug molecules forming about 0.8% of the library bound strongly to the target protein, which gave rise to Two potential structural scaffolds: (4S,4aR,5aR,12aS)-4-(dimethylamino)-10,12,12a-trihydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide and the stilbenoid-like structure. These scaffolds could serve as potential starting points in the structure-based design of anti-SARS-CoV-2 drugs.
{"title":"SEARCH FOR STRUCTURAL SCAFFOLDS AGAINST SARS-COV-2 MPRO: AN IN SILICO STUDY","authors":"E. Onah, I. Ugwoke, U. J. Eze, H. C. Eze, S. Musa, S. Ndiana-Abasi, O. Okoli, I. E. Ekeh, A. Edet","doi":"10.4314/JFAS.V13I2.7","DOIUrl":"https://doi.org/10.4314/JFAS.V13I2.7","url":null,"abstract":"The emergence of the deadly SARS-CoV-2, the etiologic agent of COVID-19 towards the end of the fourth quarter of 2019 has necessitated intensive research towards the development of drugs and vaccine that can combat the disease. Consequently, we conducted molecular docking of the e-Drug3D library using London dG and Affinity dG as scoring algorithms for common structural scaffolds in drug molecules with strong binding affinities towards SARS-CoV-2 Mpro. 15 drug molecules forming about 0.8% of the library bound strongly to the target protein, which gave rise to Two potential structural scaffolds: (4S,4aR,5aR,12aS)-4-(dimethylamino)-10,12,12a-trihydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide and the stilbenoid-like structure. These scaffolds could serve as potential starting points in the structure-based design of anti-SARS-CoV-2 drugs.","PeriodicalId":15885,"journal":{"name":"Journal of Fundamental and Applied Sciences","volume":"13 1","pages":"740-769"},"PeriodicalIF":0.0,"publicationDate":"2021-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46391818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chromosomal fragments deletions are very harmful. They are almost lethal even in the presence of a normal homologue. Autosomal monosomies are incompatible with survival. However, micro-deletions are less fatal but they often produce clinical syndromes With characteristic phenotypes. Thus, a question rises: why does our organism not tolerate the lack of genetic material ? The present work, is a profound investigation on the molecular basis of the intolerance of our organism to the lack of genetic material. The subject under discussion has never been dealt with before. Up to now, no article had been published on this matter.
{"title":"MOLECULAR BASIS OF OUR ORGANISM’S INTOLERANCE TO LACK OF GENETIC MATERIAL","authors":"S. Boumendjel","doi":"10.4314/JFAS.V13I2.5","DOIUrl":"https://doi.org/10.4314/JFAS.V13I2.5","url":null,"abstract":"Chromosomal fragments deletions are very harmful. They are almost lethal even in the presence of a normal homologue. Autosomal monosomies are incompatible with survival. However, micro-deletions are less fatal but they often produce clinical syndromes With characteristic phenotypes. Thus, a question rises: why does our organism not tolerate the lack of genetic material ? The present work, is a profound investigation on the molecular basis of the intolerance of our organism to the lack of genetic material. The subject under discussion has never been dealt with before. Up to now, no article had been published on this matter.","PeriodicalId":15885,"journal":{"name":"Journal of Fundamental and Applied Sciences","volume":"13 1","pages":"708-723"},"PeriodicalIF":0.0,"publicationDate":"2021-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45388932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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