Sizwe Ngcobo, B. Silwana, Kanyisa Maqhashu, M. Matoetoe
This study assesses the physical and electrochemical changes of bimetallic Ag-Au nanoparticle-functionalized bentonite nanoclay. Nanoclay was studied to deduce a better sensing material/film. A chemical co-reduction method was used to synthesize bimetallic Ag-Au c nanoparticles, which were used to prepare a Ag-Au/PGV bentonite composite. Bimetallic Ag-AuNPs and their nanoclay composite were optically characterized using the scanning electron microscope, ultraviolet visible spectroscopy, X-ray diffraction, and Fourier transform infrared, whilst cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used to ascertain their electrochemical activity and properties. The results of surface morphological inspection showed an average size of 10 nm, in agreement with XRD. The bimetallic Ag-AuNPs UV/Vis characteristic wavelengths of 414 nm and 516 nm confirmed the presence of Ag and Au metals, respectively. XRD exhibited diffraction planes related to 2θ values of Ag and Au metals, whilst FTIR indicated mainly COO- functional groups from the citrate capping of bimetallic Ag-Au NPs. CV and DPV showed that bentonite nanoclay is largely insulated by silicates but exhibited a small electroactivity of Fe. The electroactivity of Ag-Au/PGV bentonite exhibited peak potentials due to Ag/Ag+ and Au/Au3+ redox couples at 0.19 V/−0.20 V and 1.37 V/0.42, respectively. The Ag-Au/PGV bentonite nanocomposite exhibited the highest surface concentration of 3.25 × 10−2 cm2, a diffusion coefficient of 2.36 × −11 cm2/s, and an electron transfer rate constant (Ks) of 1.99 × 10−4 cm2. The outcome of these results indicated that the Ag-Au/PGV bentonite nanocomposite was more electroactive than PGV. Therefore, this study accentuates Ag-Au/PGV bentonite nanocomposite as a novel and promising platform for electrochemical sensing with higher sensitivity and efficiency than other sensing materials.
{"title":"Bentonite Nanoclay Optoelectrochemical Property Improvement through Bimetallic Silver and Gold Nanoparticles","authors":"Sizwe Ngcobo, B. Silwana, Kanyisa Maqhashu, M. Matoetoe","doi":"10.1155/2022/3693938","DOIUrl":"https://doi.org/10.1155/2022/3693938","url":null,"abstract":"This study assesses the physical and electrochemical changes of bimetallic Ag-Au nanoparticle-functionalized bentonite nanoclay. Nanoclay was studied to deduce a better sensing material/film. A chemical co-reduction method was used to synthesize bimetallic Ag-Au c nanoparticles, which were used to prepare a Ag-Au/PGV bentonite composite. Bimetallic Ag-AuNPs and their nanoclay composite were optically characterized using the scanning electron microscope, ultraviolet visible spectroscopy, X-ray diffraction, and Fourier transform infrared, whilst cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used to ascertain their electrochemical activity and properties. The results of surface morphological inspection showed an average size of 10 nm, in agreement with XRD. The bimetallic Ag-AuNPs UV/Vis characteristic wavelengths of 414 nm and 516 nm confirmed the presence of Ag and Au metals, respectively. XRD exhibited diffraction planes related to 2θ values of Ag and Au metals, whilst FTIR indicated mainly COO- functional groups from the citrate capping of bimetallic Ag-Au NPs. CV and DPV showed that bentonite nanoclay is largely insulated by silicates but exhibited a small electroactivity of Fe. The electroactivity of Ag-Au/PGV bentonite exhibited peak potentials due to Ag/Ag+ and Au/Au3+ redox couples at 0.19 V/−0.20 V and 1.37 V/0.42, respectively. The Ag-Au/PGV bentonite nanocomposite exhibited the highest surface concentration of 3.25 × 10−2 cm2, a diffusion coefficient of 2.36 × −11 cm2/s, and an electron transfer rate constant (Ks) of 1.99 × 10−4 cm2. The outcome of these results indicated that the Ag-Au/PGV bentonite nanocomposite was more electroactive than PGV. Therefore, this study accentuates Ag-Au/PGV bentonite nanocomposite as a novel and promising platform for electrochemical sensing with higher sensitivity and efficiency than other sensing materials.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86259490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shyam Sundar Gandi, S. Gandi, S. Parne, Motilal Lakavat, Nageswara Rao Lakkimsetty, G. Gedda
The hydrothermal treatment was used to create a natural hierarchical bio-inspired carbon and nitrogen-doped C/N/TiO2 hybrid composite. It is the goal of this work to investigate the photocatalytic activity of bio-inspired C/N/TiO2 hybrid composite. Techniques such as X-ray powder diffraction, scanning electron microscopy, UV-Vis absorption spectroscopy, FTIR, Raman, and photoluminescence spectroscopy were used to explore the structural, morphological, and photocatalysis characteristics of the bio-inspired C/N/TiO2 hybrid composite. By doping carbon and nitrogen, TiO2 nanotubes were able to improve the photocatalyst properties of the C/N/TiO2 hybrid composite, decrease the energy band gap (∼2.55 eV), and result in increased electron transfer efficiency when compared to pure TiO2. The photocatalytic degradation of pollutants (rhodamine B (RhB)) is made possible by the use of a bio-inspired C/N/TiO2 hybrid composite that has high interconnectivity and an easily accessible surface.
{"title":"Bio-Inspired C/N/TiO2 Hybrid Composite Heterostructure: Enhanced Photocatalytic Activity under Visible Light","authors":"Shyam Sundar Gandi, S. Gandi, S. Parne, Motilal Lakavat, Nageswara Rao Lakkimsetty, G. Gedda","doi":"10.1155/2022/5816063","DOIUrl":"https://doi.org/10.1155/2022/5816063","url":null,"abstract":"The hydrothermal treatment was used to create a natural hierarchical bio-inspired carbon and nitrogen-doped C/N/TiO2 hybrid composite. It is the goal of this work to investigate the photocatalytic activity of bio-inspired C/N/TiO2 hybrid composite. Techniques such as X-ray powder diffraction, scanning electron microscopy, UV-Vis absorption spectroscopy, FTIR, Raman, and photoluminescence spectroscopy were used to explore the structural, morphological, and photocatalysis characteristics of the bio-inspired C/N/TiO2 hybrid composite. By doping carbon and nitrogen, TiO2 nanotubes were able to improve the photocatalyst properties of the C/N/TiO2 hybrid composite, decrease the energy band gap (∼2.55 eV), and result in increased electron transfer efficiency when compared to pure TiO2. The photocatalytic degradation of pollutants (rhodamine B (RhB)) is made possible by the use of a bio-inspired C/N/TiO2 hybrid composite that has high interconnectivity and an easily accessible surface.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80064865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Mohamed, E. Fawzy, R. Shehab, M. Abdel-Salam, Rawheya A. Salah El Din, Hesham M. Abd El Fatah
A green, eco-friendly approach to biosynthesizing silver nanoparticles has been reported for marine macroalga (Cystoseira myrica) extract as a reducing agent. Different pH and temperature impact the green synthesis of silver nanoparticles suggesting that the synthesis depends greatly on pH and temperature. The structure and characters of synthesized nanoparticles were confirmed using HR-TEM, DLS, XRD, and FTIR. Cytotoxicity was indicated using provided cell lines of breast carcinoma cells (MCF-7) and human hepatocellular carcinoma cells (HepG2). Shape of silver nanoparticles at pH 9 and 75°C for 30 min was found to be suitable for the biosynthesis process and the AgNPs exhibited a characteristic absorption peak at 434 nm. High Resolution Electron Microscope Transmission reported polydisperse and spherical shapes ranging from 8 to 15 nm. High attractive and repulsive forces between each nanoparticle were recorded with an average zeta-potential value of approximately −29.3 mV. The X-ray diffraction study revealed the crystalline structure of silver nanoparticles. FTIR has shown the bioreduction of silver ions to silver nanoparticles through biomolecules found in algal extract. Silver nanoparticles have been found to have anticancer activity. The cytotoxicity assay was studied against MCF-7 and HepG2 at various concentrations (100, 50, 25, 12.5, 6.25, 3.125, 1.56, 0.78, 0.39, 0.2, and 0.1 μg/mL). By increasing the concentration of AgNPs from 0.1 to 100 μg/mL, the maximum percentage of viability against MCF-7 and HepG2 cell line decreased from 94.55 ± 7.55 to 19.879 ± 0.503 and from 78.56 ± 11.36 to 25.81 ± 2.66 after time exposure, respectively.
{"title":"Production, Characterization, and Cytotoxicity Effects of Silver Nanoparticles from Brown Alga (Cystoseira myrica)","authors":"R. Mohamed, E. Fawzy, R. Shehab, M. Abdel-Salam, Rawheya A. Salah El Din, Hesham M. Abd El Fatah","doi":"10.1155/2022/6469090","DOIUrl":"https://doi.org/10.1155/2022/6469090","url":null,"abstract":"A green, eco-friendly approach to biosynthesizing silver nanoparticles has been reported for marine macroalga (Cystoseira myrica) extract as a reducing agent. Different pH and temperature impact the green synthesis of silver nanoparticles suggesting that the synthesis depends greatly on pH and temperature. The structure and characters of synthesized nanoparticles were confirmed using HR-TEM, DLS, XRD, and FTIR. Cytotoxicity was indicated using provided cell lines of breast carcinoma cells (MCF-7) and human hepatocellular carcinoma cells (HepG2). Shape of silver nanoparticles at pH 9 and 75°C for 30 min was found to be suitable for the biosynthesis process and the AgNPs exhibited a characteristic absorption peak at 434 nm. High Resolution Electron Microscope Transmission reported polydisperse and spherical shapes ranging from 8 to 15 nm. High attractive and repulsive forces between each nanoparticle were recorded with an average zeta-potential value of approximately −29.3 mV. The X-ray diffraction study revealed the crystalline structure of silver nanoparticles. FTIR has shown the bioreduction of silver ions to silver nanoparticles through biomolecules found in algal extract. Silver nanoparticles have been found to have anticancer activity. The cytotoxicity assay was studied against MCF-7 and HepG2 at various concentrations (100, 50, 25, 12.5, 6.25, 3.125, 1.56, 0.78, 0.39, 0.2, and 0.1 μg/mL). By increasing the concentration of AgNPs from 0.1 to 100 μg/mL, the maximum percentage of viability against MCF-7 and HepG2 cell line decreased from 94.55 ± 7.55 to 19.879 ± 0.503 and from 78.56 ± 11.36 to 25.81 ± 2.66 after time exposure, respectively.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81391700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sareh Bagheri-Josheghani, B. Bakhshi, Shahin Najar-Peerayeh
Nowadays, nanovaccine is considered as an evolving method in the field of vaccination to induce immunity in the human body against various diseases, including bacterial or viral diseases as well as virulent tumors. Nanovaccines are more efficient than traditional vaccines since they could potentially induce both humoral and cellular immune reactions. Various studies have shown that nanoparticles with multiple compounds have been designed as delivery systems or as adjuvants for vaccines. Nanoparticles could function as a drug delivery tool, as an adjuvant to promote antigen processing, and as an immune modulator to induce immune responses. These nanoparticles generate immune responses through activating immune cells as well as through the production of antibody responses. Design engineering of nanoparticles (NPs) used to produce nanovaccines to induce immunity in the human body needs comprehensive information about the ways they interact with the component of immune system. Challenges remain due to the lack of sufficient and comprehensive information about the nanoparticles' mode of action. Several studies have described the interactions between various classes of nanoparticles and the immune system in the field of prevention of bacterial infections. The results of some studies conducted in recent years on the interaction between nanoparticles and biosystems have considerably affected the methods used to design nanoparticles for medical applications. In this review, NPs’ characteristics influencing their interplay with the immune system were discussed in vivo. The information obtained could lead to the development of strategies for rationalizing the design of nanovaccines in order to achieve optimum induction of immune response.
{"title":"The Influence of Nanoparticle on Vaccine Responses against Bacterial Infection","authors":"Sareh Bagheri-Josheghani, B. Bakhshi, Shahin Najar-Peerayeh","doi":"10.1155/2022/6856982","DOIUrl":"https://doi.org/10.1155/2022/6856982","url":null,"abstract":"Nowadays, nanovaccine is considered as an evolving method in the field of vaccination to induce immunity in the human body against various diseases, including bacterial or viral diseases as well as virulent tumors. Nanovaccines are more efficient than traditional vaccines since they could potentially induce both humoral and cellular immune reactions. Various studies have shown that nanoparticles with multiple compounds have been designed as delivery systems or as adjuvants for vaccines. Nanoparticles could function as a drug delivery tool, as an adjuvant to promote antigen processing, and as an immune modulator to induce immune responses. These nanoparticles generate immune responses through activating immune cells as well as through the production of antibody responses. Design engineering of nanoparticles (NPs) used to produce nanovaccines to induce immunity in the human body needs comprehensive information about the ways they interact with the component of immune system. Challenges remain due to the lack of sufficient and comprehensive information about the nanoparticles' mode of action. Several studies have described the interactions between various classes of nanoparticles and the immune system in the field of prevention of bacterial infections. The results of some studies conducted in recent years on the interaction between nanoparticles and biosystems have considerably affected the methods used to design nanoparticles for medical applications. In this review, NPs’ characteristics influencing their interplay with the immune system were discussed in vivo. The information obtained could lead to the development of strategies for rationalizing the design of nanovaccines in order to achieve optimum induction of immune response.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74326662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Cortés-Camargo, Angélica Jiménez-Rosales, P. E. Acuña-Avila
Ustilago maydis (UM) is a fungus that grows naturally on Zea mays; it reduces the corn yields, and thus, it represents huge economic loss; however, it can be used as an exotic food, and in the present work, it is successfully used as a reducing and stabilizing agent for the preparation of silver nanoparticles (Ag NPs) due to its content of amino acids and biosurfactants. The effects of the concentration of UM aqueous extract, pH, and sunlight on the particle size, surface plasmon resonance, stability, and morphology of Ag NPs obtained by green synthesis were evaluated. A green reduction was observed only in presence of UM, and colloidal Ag NPs were obtained with or without the presence of sunlight; nevertheless, continuous sunlight exposure greatly increased the reaction rate. Ag NPs tend to increase in size from 153 nm to 1400 nm at a higher pH and a greater amount of UM, and also, UM tends to stabilize the Ag NPs preventing their agglomeration according to measurement of zeta potential (−10.75 ± 0.84 mV) and SEM observation; furthermore, surface plasmon resonances were more intense between 400 and 480 nm of wavelength adding greater amount of UM. This study concludes that UM not only reduces AgNO3 but also acts as stabilizer of Ag NPs.
{"title":"Green Synthesis of Ag NPs Using Ustilago maydis as Reducing and Stabilizing Agent","authors":"S. Cortés-Camargo, Angélica Jiménez-Rosales, P. E. Acuña-Avila","doi":"10.1155/2022/2494882","DOIUrl":"https://doi.org/10.1155/2022/2494882","url":null,"abstract":"Ustilago maydis (UM) is a fungus that grows naturally on Zea mays; it reduces the corn yields, and thus, it represents huge economic loss; however, it can be used as an exotic food, and in the present work, it is successfully used as a reducing and stabilizing agent for the preparation of silver nanoparticles (Ag NPs) due to its content of amino acids and biosurfactants. The effects of the concentration of UM aqueous extract, pH, and sunlight on the particle size, surface plasmon resonance, stability, and morphology of Ag NPs obtained by green synthesis were evaluated. A green reduction was observed only in presence of UM, and colloidal Ag NPs were obtained with or without the presence of sunlight; nevertheless, continuous sunlight exposure greatly increased the reaction rate. Ag NPs tend to increase in size from 153 nm to 1400 nm at a higher pH and a greater amount of UM, and also, UM tends to stabilize the Ag NPs preventing their agglomeration according to measurement of zeta potential (−10.75 ± 0.84 mV) and SEM observation; furthermore, surface plasmon resonances were more intense between 400 and 480 nm of wavelength adding greater amount of UM. This study concludes that UM not only reduces AgNO3 but also acts as stabilizer of Ag NPs.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72580365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hybrid nanofluids developed with the fusion or suspension of two or more different nanoparticles in a mixture as a novel heat transfer fluid are currently of interest to researchers due to their proven better measured thermal conductivities. Several reviewed articles exist on the thermal conductivity of hybrid nanofluids, a vital property for which the heat transfer rate is directly dependent. This review aims to understand the current developments in hybrid nanofluids and their applications. An extensive literature survey was carried out of heuristic-based articles published in the last 15 years. The review reiterates topical research on the preparation methods and ways to improve the stability of readied fluid, thermophysical properties of mixture nanofluids, and some empirical correlations developed for estimating thermal conductivity. Hybrid nanofluid studies on heat transfer performance in automobile radiator cooling systems were also obtained and discussed. The review’s significant findings include the following: (1) hybrid nanofluids produce a noticeable thermal conductivity enhancement and a relatively higher heat transfer coefficient than mono nanofluids and regular liquids. Furthermore, through the uniform dispersion and stable suspension of nanoparticles in the host liquids, the maximum possible thermal augmentation can be obtained at the lowest possible concentrations (by <0.1% by volume). (2) An automobile radiator’s overall heat transfer accomplishment can thus be boosted by using a mixture of nanofluids as conventional coolants. Up-to-date literature results on the thermal conductivity enhancement of mixture fluids are also presented in this study. Nonetheless, some of the barriers and challenges acknowledged in this work must be addressed for its complete deployment in modern applications.
{"title":"A Perspective Review on Thermal Conductivity of Hybrid Nanofluids and Their Application in Automobile Radiator Cooling","authors":"W. E. Ukueje, F. Abam, A. Obi","doi":"10.1155/2022/2187932","DOIUrl":"https://doi.org/10.1155/2022/2187932","url":null,"abstract":"Hybrid nanofluids developed with the fusion or suspension of two or more different nanoparticles in a mixture as a novel heat transfer fluid are currently of interest to researchers due to their proven better measured thermal conductivities. Several reviewed articles exist on the thermal conductivity of hybrid nanofluids, a vital property for which the heat transfer rate is directly dependent. This review aims to understand the current developments in hybrid nanofluids and their applications. An extensive literature survey was carried out of heuristic-based articles published in the last 15 years. The review reiterates topical research on the preparation methods and ways to improve the stability of readied fluid, thermophysical properties of mixture nanofluids, and some empirical correlations developed for estimating thermal conductivity. Hybrid nanofluid studies on heat transfer performance in automobile radiator cooling systems were also obtained and discussed. The review’s significant findings include the following: (1) hybrid nanofluids produce a noticeable thermal conductivity enhancement and a relatively higher heat transfer coefficient than mono nanofluids and regular liquids. Furthermore, through the uniform dispersion and stable suspension of nanoparticles in the host liquids, the maximum possible thermal augmentation can be obtained at the lowest possible concentrations (by <0.1% by volume). (2) An automobile radiator’s overall heat transfer accomplishment can thus be boosted by using a mixture of nanofluids as conventional coolants. Up-to-date literature results on the thermal conductivity enhancement of mixture fluids are also presented in this study. Nonetheless, some of the barriers and challenges acknowledged in this work must be addressed for its complete deployment in modern applications.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2022-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90676234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Nguyen, Tinh Ngoc Tran, A. C. Ha, Phu Dai Huynh
Biopolymer of natural origin as chitosan has been studied and applied widely in practice. In the pharmaceutical field, especially, chitosan nanoparticles have been researched for a variety of drug delivery systems. There are many factors influencing the success of the chitosan nanoparticle delivery system. Therein, the specific parameters to the physicochemical nature of chitosan greatly determine the efficiency of its drugs carrier. The degree of deacetylation (DD) of chitosan is one of those parameters. In this study, the influence of DD on chitosan properties was clarified to facilitate the preparation of nanoparticles by the electrospraying method. DD can affect the solubility, crystallinity, and surface tension of chitosan, but it cannot strongly impact the viscosity of chitosan solution as much as the molecular weight (Mv). From these results, M3 chitosan, owning a high DD of 86.70%, and crystalline index of 44%, was dissolved in acetic acid for the collection of electrosprayed nanoparticles. The M3 solution having low viscosity of under 50 mm2/s displayed the easy adjustment of the stable Taylor-cone droplet at the nozzle tip. Particularly, the M3 chitosan solution with a concentration of 1.5 wt.% in acetic acid of 90 wt.% concentration operated at the working condition of 12 kV voltage, a distance between the two electrodes of 10 cm created spherical particles with an average diameter of 338 nm, narrow size distribution. These chitosan nanoparticles can obtain the initial requirement for application as injectable drugs carrier.
{"title":"Impact of Deacetylation Degree on Properties of Chitosan for Formation of Electrosprayed Nanoparticles","authors":"H. Nguyen, Tinh Ngoc Tran, A. C. Ha, Phu Dai Huynh","doi":"10.1155/2022/2288892","DOIUrl":"https://doi.org/10.1155/2022/2288892","url":null,"abstract":"Biopolymer of natural origin as chitosan has been studied and applied widely in practice. In the pharmaceutical field, especially, chitosan nanoparticles have been researched for a variety of drug delivery systems. There are many factors influencing the success of the chitosan nanoparticle delivery system. Therein, the specific parameters to the physicochemical nature of chitosan greatly determine the efficiency of its drugs carrier. The degree of deacetylation (DD) of chitosan is one of those parameters. In this study, the influence of DD on chitosan properties was clarified to facilitate the preparation of nanoparticles by the electrospraying method. DD can affect the solubility, crystallinity, and surface tension of chitosan, but it cannot strongly impact the viscosity of chitosan solution as much as the molecular weight (Mv). From these results, M3 chitosan, owning a high DD of 86.70%, and crystalline index of 44%, was dissolved in acetic acid for the collection of electrosprayed nanoparticles. The M3 solution having low viscosity of under 50 mm2/s displayed the easy adjustment of the stable Taylor-cone droplet at the nozzle tip. Particularly, the M3 chitosan solution with a concentration of 1.5 wt.% in acetic acid of 90 wt.% concentration operated at the working condition of 12 kV voltage, a distance between the two electrodes of 10 cm created spherical particles with an average diameter of 338 nm, narrow size distribution. These chitosan nanoparticles can obtain the initial requirement for application as injectable drugs carrier.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2022-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78791188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Owida, Jamal I. Al-Nabulsi, Nidal M. Turab, Nawal Louzi
The global outbreak of coronavirus disease has sent an ominous message to the field of innovative and advanced technology research and development (COVID-19). To accomplish this, convectional technology and recent discoveries can be combined, or new research directions can be opened up using nanotechnology. Nanotechnology can be used to prevent, diagnose, and treat SARS-CoV-2 infection. As the pandemic spreads, a thorough examination of nanomaterials' role in pandemic response is highly desirable. According to this comprehensive review article, nanotechnology can be used to prevent, diagnose, and treat COVID-19. This research will be extremely useful during the COVID-19 outbreak in terms of developing rules for designing nanostructure materials to combat the outbreak.
{"title":"Nanotechnology Role Development for COVID-19 Pandemic Management","authors":"H. Owida, Jamal I. Al-Nabulsi, Nidal M. Turab, Nawal Louzi","doi":"10.1155/2022/1872933","DOIUrl":"https://doi.org/10.1155/2022/1872933","url":null,"abstract":"The global outbreak of coronavirus disease has sent an ominous message to the field of innovative and advanced technology research and development (COVID-19). To accomplish this, convectional technology and recent discoveries can be combined, or new research directions can be opened up using nanotechnology. Nanotechnology can be used to prevent, diagnose, and treat SARS-CoV-2 infection. As the pandemic spreads, a thorough examination of nanomaterials' role in pandemic response is highly desirable. According to this comprehensive review article, nanotechnology can be used to prevent, diagnose, and treat COVID-19. This research will be extremely useful during the COVID-19 outbreak in terms of developing rules for designing nanostructure materials to combat the outbreak.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84237423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. T. Tran, H. V. Tran, H. Cao, T. H. Tran, C. D. Huynh
Electrochemical DNA sensors based on nanocomposite materials of polyaniline nanowires (PANi NWs) have been published in the literature. However, it is interesting that there are very few research studies related to the development of electrochemical DNA sensors based on PANi NWs individually. In this study, PANi NWs were synthesized site-specifically on a Pt microelectrode with only 0.785 mm2 area using an electropolymerization procedure. The electrosynthesis allows direct deposition of PANi NWs onto the Pt microelectrode in a rapid and cost-effective way. The good properties of PANi NWs including uniform size, uniform distribution throughout the Pt working electrode, and H2SO4 doping which improved the conductivity of the PANi material were obtained. Especially, the electrochemically effective surface area of the PANi NW-based Pt microelectrode determined in this work is nearly 19 times larger than that of the Pt working electrode. The PANi NW layer with large electrochemically effective surface area and high biocompatibility is consistent with the application in electrochemical DNA sensors. The fabricated DNA sensors show advantages such as simple fabrication, direct detection, high sensitivity (with the detection limit of 2.48 × 10−14 M), good specificity, and low sample volume requirement. This study also contributes to confirm the role of PANi NWs in DNA probe immobilization as well as in electrochemical signal transmission in the development of electrochemical DNA sensors.
{"title":"Electrochemically Effective Surface Area of a Polyaniline Nanowire-Based Platinum Microelectrode and Development of an Electrochemical DNA Sensor","authors":"L. T. Tran, H. V. Tran, H. Cao, T. H. Tran, C. D. Huynh","doi":"10.1155/2022/8947080","DOIUrl":"https://doi.org/10.1155/2022/8947080","url":null,"abstract":"Electrochemical DNA sensors based on nanocomposite materials of polyaniline nanowires (PANi NWs) have been published in the literature. However, it is interesting that there are very few research studies related to the development of electrochemical DNA sensors based on PANi NWs individually. In this study, PANi NWs were synthesized site-specifically on a Pt microelectrode with only 0.785 mm2 area using an electropolymerization procedure. The electrosynthesis allows direct deposition of PANi NWs onto the Pt microelectrode in a rapid and cost-effective way. The good properties of PANi NWs including uniform size, uniform distribution throughout the Pt working electrode, and H2SO4 doping which improved the conductivity of the PANi material were obtained. Especially, the electrochemically effective surface area of the PANi NW-based Pt microelectrode determined in this work is nearly 19 times larger than that of the Pt working electrode. The PANi NW layer with large electrochemically effective surface area and high biocompatibility is consistent with the application in electrochemical DNA sensors. The fabricated DNA sensors show advantages such as simple fabrication, direct detection, high sensitivity (with the detection limit of 2.48 × 10−14 M), good specificity, and low sample volume requirement. This study also contributes to confirm the role of PANi NWs in DNA probe immobilization as well as in electrochemical signal transmission in the development of electrochemical DNA sensors.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2022-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89538919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Olawale, O. Oladimeji, M. Ariatti, Moganavelli Singh
The last few decades have seen an overwhelming increase in the amount of research carried out on the use of inorganic nanoparticles. More fascinating is the tremendous progress made in the use of chalcogen and chalcogenide nanoparticles in cancer theranostics. These nanomaterials, which were initially synthesized through chemical methods, have now been efficiently produced using different plant materials. The paradigm shift towards the biogenic route of nanoparticle synthesis stems from its superior advantages of biosafety, eco-friendliness, and simplicity, among others. Despite a large number of reviews available on inorganic nanoparticle synthesis through green chemistry, there is currently a dearth of information on the green synthesis of chalcogens and chalcogenides for cancer research. Nanoformulations involving chalcogens such as sulfur, selenium, and tellurium and their respective chalcogenides have recently emerged as promising tools in cancer therapeutics and diagnosis. Similar to other inorganic nanoparticles, chalcogens and chalcogenides have been synthesized using plant extracts and their purified biomolecules. In this review, we provide an up-to-date discussion of the recent progress that has been made in the plant-mediated synthesis of chalcogens and chalcogenides with a special focus on their application in cancer theranostics.
{"title":"Emerging Roles of Green-Synthesized Chalcogen and Chalcogenide Nanoparticles in Cancer Theranostics","authors":"F. Olawale, O. Oladimeji, M. Ariatti, Moganavelli Singh","doi":"10.1155/2022/6176610","DOIUrl":"https://doi.org/10.1155/2022/6176610","url":null,"abstract":"The last few decades have seen an overwhelming increase in the amount of research carried out on the use of inorganic nanoparticles. More fascinating is the tremendous progress made in the use of chalcogen and chalcogenide nanoparticles in cancer theranostics. These nanomaterials, which were initially synthesized through chemical methods, have now been efficiently produced using different plant materials. The paradigm shift towards the biogenic route of nanoparticle synthesis stems from its superior advantages of biosafety, eco-friendliness, and simplicity, among others. Despite a large number of reviews available on inorganic nanoparticle synthesis through green chemistry, there is currently a dearth of information on the green synthesis of chalcogens and chalcogenides for cancer research. Nanoformulations involving chalcogens such as sulfur, selenium, and tellurium and their respective chalcogenides have recently emerged as promising tools in cancer therapeutics and diagnosis. Similar to other inorganic nanoparticles, chalcogens and chalcogenides have been synthesized using plant extracts and their purified biomolecules. In this review, we provide an up-to-date discussion of the recent progress that has been made in the plant-mediated synthesis of chalcogens and chalcogenides with a special focus on their application in cancer theranostics.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2022-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90470696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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